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Astellas Pharma Inc. (4503.T)

JPY2,142.50 +21.50 (+1.01%)
JP JPX Healthcare Drug Manufacturers - General
Address 2-5-1, Nihonbashi-Honcho 103-8411
Tokyo, JP
CEO Naoki Okamura
IPO 2000-01-04
ISIN JP3942400007

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Also trades on Other OTC · ALPMF (USD) Other OTC · ALPMY (USD) Tokyo Stock Exchange · 4503.T (JPY)
Description

Astellas Pharma Inc., a venerable Japanese pharmaceutical enterprise established in 1923 and headquartered in Tokyo, operates globally in the research, development, manufacturing, and commercialization of a diverse range of medications. Its extensive product lineup addresses critical health needs, including various oncology treatments such as XTANDI for prostate cancer, XOSPATA, an FLT3 inhibitor for specific relapsed or refractory acute myeloid leukemia, and PADCEV for advanced urothelial cancer. For urological conditions, Astellas offers Betanis/Myrbetriq/BETMIGA to manage symptoms of overactive bladder, mirabegron for neurogenic detrusor overactivity in children, and Vesicare for OAB. Other notable pharmaceuticals include Eligard for prostate cancer, Harnal/Omnic for benign prostatic hyperplasia, Evrenzo for anemia associated with chronic kidney disease, and the immunosuppressants Prograf/Advagraf/Graceptor/ASTAGRAF, vital for preventing organ transplant rejection. The company also markets Funguard/MYCAMINE, an antifungal agent. Astellas actively fosters innovation through numerous strategic collaborations and partnerships. These include clinical trial agreements with pharmaceutical giants like Merck & Co., Inc. and CytomX Therapeutics, Inc. Demonstrating a broader approach to health, they collaborate with BANDAI NAMCO Entertainment Inc. on developing a smartphone exercise support application. In the realm of scientific discovery, Astellas maintains a research alliance with Harvard University for joint therapeutic and technological advancements. Further research initiatives involve Actinium Pharmaceuticals, Inc. to advance targeted radiotherapies leveraging their Antibody Warhead Enabling platform, an agreement with Zenith Epigenetics Ltd. to evaluate ZEN-3694, and a collaboration with Cytokinetics, Incorporated. A significant strategic alliance and license agreement exist with Minovia Therapeutics Ltd. to research, develop, and commercialize cell therapies for mitochondrial dysfunction.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
JPY2,142.50 +21.50 (+1.01%)
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Volume Profile
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Liquidity & share structure
Average Volume
6M
Beta
0.07
Float Shares
1.79B
Free Float %
100.0%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
+7.49% +0.79% +2.28% -12.24% +15.95% +7.18% +59.76% +0.84% +27.01% +52.86% +246.96%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
vs.
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Price Targets & DCF
Current price
2,142.50
DCF (Unlevered) 13,173.30 +514.9%
DCF (Levered) 11,253.27 +425.2%

DCF figures are point estimates: small changes in growth or discount-rate assumptions move them materially. Read them as a reference, not a precise target.

Ratings Trend (MoM) 29% Bullish
Rating 2026-05 Change
Strong Buy 0 0
Buy 4 0
Hold 9 0
Sell 0 0
Strong Sell 1 0
Quality scores
Altman Z-Score
2.83
Grey zone
Piotroski F-Score
7 / 9
Strong
MOAT Score
7 / 10
Strong MOAT
Composite Rating
A
Overall Score
4 / 5
High
DCF Score
5 / 5
High
ROE Score
5 / 5
High
ROA Score
5 / 5
High
D/E Score
2 / 5
Medium
P/E Score
2 / 5
Medium
P/Book Score
3 / 5
Medium
Operational MOAT
✗ Below peers
  • Revenue growth Drug Manufacturers - General: +6.6%
    +11.9% Q1'26: +17.1% (vs Q1'25)
  • EPS growth Drug Manufacturers - General: +18.2%
    +474.4% Q1'26: -42.2% (vs Q1'25)
  • FCF margin FCF growth · Drug Manufacturers - General: +36.0%
    +22.7% Q1'26: +35.0% (vs Q1'25)
  • EBIT margin Drug Manufacturers - General: +19.4%
    +19.6% Q1'26: +14.5% (vs Q1'25)
  • ROIC Drug Manufacturers - General: +10.2%
    +15.4% Q1'26: +13.4% (vs Q1'25)
  • Share dilution Drug Manufacturers - General: +0.0%
    +0.0% Q1'26: +0.7% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Drug Manufacturers - General: -0.29×
    0.92× Q1'26: 1.10× (vs Q1'25)
Valuation Multiples From To
Price Forecast (3Y) From To
Model
Adjust
P/E
Theoretical Return — If Invested Today

* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.

DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (0.08) × ERP
WACC = 88% × Ke + 12% × Kd (4.1%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Intrinsic value (base): 13,173.30 Current price: 2,142.50
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Mar 2015
actual
Mar 2016
actual
Mar 2017
actual
Mar 2018
actual
Mar 2019
actual
Mar 2020
actual
Mar 2021
actual
Mar 2022
actual
Mar 2023
actual
Mar 2024
actual
Mar 2025
actual
Mar 2026
13 Rev. Ana.
12 EPS Ana.
Mar 2027
13 Rev. Ana.
11 EPS Ana.
Mar 2028
12 Rev. Ana.
11 EPS Ana.
Mar 2029
11 Rev. Ana.
9 EPS Ana.
Mar 2030
7 Rev. Ana.
3 EPS Ana.
Mar 2031
7 Rev. Ana.
4 EPS Ana.
Revenue
1.25T
est: 1.24T (+0.6%)
1.37T
est: 1.39T (-1.3%)
1.31T
est: 1.32T (-1.0%)
1.30T
est: 1.30T (-0.2%)
1.31T
est: 1.30T (+0.3%)
1.30T
est: 1.27T (+2.2%)
1.25T
est: 1.26T (-0.8%)
1.30T
est: 1.32T (-1.6%)
1.52T
est: 1.51T (+0.7%)
1.60T
est: 1.70T (-5.8%)
1.91T
est: 1.90T (+0.4%)
2.13T
2.09T – 2.20T
+11.6% YoY
2.24T
2.20T – 2.35T
+5.6% YoY
2.08T
1.97T – 2.23T
-7.4% YoY
1.84T
1.84T – 1.85T
-11.2% YoY
1.71T
1.65T – 1.81T
-7.4% YoY
1.77T
1.71T – 1.88T
+3.9% YoY
EBITDA
292.35B
est: 191.49B (+52.7%)
338.69B
est: 214.60B (+57.8%)
337.61B
est: 204.50B (+65.1%)
336.68B
est: 201.14B (+67.4%)
345.87B
est: 201.04B (+72.0%)
333.88B
est: 196.58B (+69.8%)
323.58B
est: 194.44B (+66.4%)
297.83B
est: 203.42B (+46.4%)
337.39B
est: 232.73B (+45.0%)
282.45B
est: 393.85B (-28.3%)
462.67B
est: 440.84B (+5.0%)
491.93B
483.28B – 509.45B
+11.6% YoY
519.37B
509.61B – 543.03B
+5.6% YoY
480.87B
456.88B – 515.68B
-7.4% YoY
426.97B
426.87B – 427.07B
-11.2% YoY
395.42B
382.09B – 418.53B
-7.4% YoY
410.74B
396.89B – 434.74B
+3.9% YoY
EBIT
226.87B
est: 94.29B (+140.6%)
269.50B
est: 105.67B (+155.0%)
273.81B
est: 100.70B (+171.9%)
271.82B
est: 99.04B (+174.4%)
282.42B
est: 98.99B (+185.3%)
267.48B
est: 96.80B (+176.3%)
250.93B
est: 95.74B (+162.1%)
218.15B
est: 100.17B (+117.8%)
231.65B
est: 114.60B (+102.1%)
124.61B
est: 249.33B (-50.0%)
263.54B
est: 279.08B (-5.6%)
311.42B
305.94B – 322.50B
+11.6% YoY
328.79B
322.61B – 343.77B
+5.6% YoY
304.42B
289.23B – 326.45B
-7.4% YoY
270.29B
270.23B – 270.36B
-11.2% YoY
250.32B
241.88B – 264.95B
-7.4% YoY
260.02B
251.25B – 275.21B
+3.9% YoY
Net Income
135.86B
est: 120.77B (+12.5%)
193.69B
est: 149.20B (+29.8%)
218.70B
est: 176.44B (+23.9%)
164.68B
est: 159.22B (+3.4%)
222.27B
est: 204.77B (+8.5%)
195.41B
est: 205.32B (-4.8%)
120.59B
est: 168.84B (-28.6%)
124.09B
est: 168.12B (-26.2%)
98.71B
est: 151.84B (-35.0%)
17.05B
est: 21.52B (-20.8%)
50.75B
est: 18.40B (+175.8%)
291.54B
230.46B – 406.32B
+1,484.4% YoY
347.06B
278.74B – 445.18B
+19.0% YoY
326.31B
224.99B – 481.88B
-6.0% YoY
247.52B
122.97B – 433.43B
-24.1% YoY
222.07B
212.34B – 238.94B
-10.3% YoY
228.23B
218.23B – 245.57B
+2.8% YoY
SGA
452.52B
est: 531.99B (-14.9%)
500.36B
est: 596.19B (-16.1%)
470.78B
est: 568.14B (-17.1%)
478.33B
est: 558.79B (-14.4%)
490.26B
est: 558.53B (-12.2%)
499.30B
est: 546.14B (-8.6%)
504.32B
est: 540.19B (-6.6%)
548.84B
est: 565.15B (-2.9%)
630.27B
est: 646.56B (-2.5%)
740.11B
est: 729.38B (+1.5%)
843.03B
est: 816.40B (+3.3%)
911.02B
895.00B – 943.45B
+11.6% YoY
961.83B
943.76B – 1.01T
+5.6% YoY
890.54B
846.10B – 955.00B
-7.4% YoY
790.72B
790.53B – 790.90B
-11.2% YoY
732.29B
707.60B – 775.08B
-7.4% YoY
760.65B
735.01B – 805.10B
+3.9% YoY
EPS
61.50
est: 67.20 (-8.5%)
89.75
est: 83.02 (+8.1%)
103.69
est: 98.18 (+5.6%)
81.11
est: 88.60 (-8.4%)
115.05
est: 113.94 (+1.0%)
104.15
est: 114.25 (-8.8%)
64.93
est: 93.95 (-30.9%)
67.08
est: 93.55 (-28.3%)
54.24
est: 84.49 (-35.8%)
9.50
est: 12.01 (-20.9%)
28.35
est: 10.08 (+181.3%)
157.09
128.24 – 226.10
+1,458.9% YoY
183.78
155.10 – 247.72
+17.0% YoY
183.44
125.20 – 268.14
-0.2% YoY
140.07
68.42 – 241.18
-23.6% YoY
123.57
118.15 – 132.96
-11.8% YoY
127.00
121.43 – 136.65
+2.8% YoY
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-29 A 4/5 5/5 5/5 5/5 2/5 2/5 3/5
2026-05-28 A 4/5 5/5 5/5 5/5 2/5 2/5 3/5
2026-05-27 A- 4/5 5/5 4/5 5/5 2/5 2/5 3/5
2026-05-26 A- 4/5 5/5 4/5 5/5 2/5 2/5 3/5
2026-05-25 A 4/5 5/5 5/5 5/5 2/5 2/5 3/5
2026-05-22 A- 4/5 5/5 4/5 5/5 2/5 2/5 3/5
2026-05-21 A 4/5 5/5 5/5 5/5 2/5 2/5 3/5
2026-05-20 A 4/5 5/5 5/5 5/5 2/5 2/5 3/5
2026-05-19 A 4/5 5/5 5/5 5/5 2/5 2/5 3/5
2026-05-18 A 4/5 5/5 5/5 5/5 2/5 2/5 3/5
2026-05-15 A 4/5 5/5 5/5 5/5 2/5 3/5 3/5
2026-05-14 A 4/5 5/5 5/5 5/5 2/5 3/5 3/5
2026-05-13 A 4/5 5/5 4/5 5/5 2/5 3/5 3/5
2026-05-12 A 4/5 5/5 4/5 5/5 2/5 3/5 3/5
2026-05-11 A 4/5 5/5 4/5 5/5 2/5 3/5 3/5
2026-05-08 A 4/5 5/5 4/5 5/5 2/5 3/5 3/5
2026-05-07 A 4/5 5/5 4/5 5/5 2/5 3/5 3/5
2026-05-01 A 4/5 5/5 4/5 5/5 2/5 3/5 3/5
2026-04-30 A 4/5 5/5 4/5 5/5 2/5 3/5 3/5
2026-04-28 A 4/5 5/5 4/5 5/5 2/5 3/5 3/5
2026-04-27 A 4/5 5/5 5/5 5/5 1/5 3/5 3/5
2026-04-24 A- 4/5 5/5 4/5 5/5 1/5 3/5 3/5
2026-04-23 A- 4/5 5/5 4/5 5/5 1/5 3/5 3/5
2026-04-22 A- 4/5 4/5 4/5 5/5 1/5 3/5 3/5
2026-04-21 A- 4/5 4/5 4/5 5/5 1/5 3/5 3/5
2026-04-20 A- 4/5 4/5 4/5 5/5 1/5 3/5 3/5
2026-04-17 A- 4/5 4/5 4/5 5/5 1/5 3/5 3/5
2026-04-16 A- 4/5 4/5 4/5 5/5 1/5 3/5 3/5
2026-04-15 A- 4/5 4/5 4/5 5/5 1/5 3/5 3/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
551.15B
OE per share TTM
306.34
Owner's Yield
13.44%
Maintenance CapEx ratio
4.20%
Maint CapEx / Avg PPE
18.8%

Ownership Overview

Ownership breakdown

Ownership breakdown not available.

At a glance
Institutional holders
Total invested
Insider transactions (90d)
0
Beneficial owners (>5%)
0
Beneficial owners (>5%)

No beneficial ownership filings recorded.

Institutional Activity (13F)

Institutional ownership trend

Institutional history not available.

Top institutional holders

Top holders not available.

Insider Activity

Insider Activity — Latest Quarter

No insider activity available.

Insider buys vs sells (history)

Insider history not available.

Recent insider transactions

No recent insider transactions.

Executive team

Top executives
EBIT / Employee
28.45M
Shares Outstanding
1.79B

Executive compensation

Executive compensation (annual)

Executive compensation not available.

CEO compensation breakdown

No CEO compensation history available.

Proxy statements

Proxy statements (DEF 14A)

No proxy statements available for this company yet.

Recent SEC filings

Recent SEC filings

No SEC filings available for this company yet.

Executive team

NameTitleCompensationGender
Naoki Okamura President, Chief Executive Officer & Director 428M male
Katsuyoshi Sugita Executive Vice President, Chief People Officer & Representative Director 185M male
Leticia Delgado-Herrera Vice President and Rx+ M&D Head female
Nobuaki Tanaka President of Japan Commercial & Senior Corporate Executive male
Nobue Yasuda General Manager of Finance & Accounting Department
Nobuko Kato Chief Communications & Investor Relations Officer female
Tatjana Dragovic General Counsel, Chief Ethics & Compliance Officer female
Atsushi Kitamura Senior Executive Officer & Chief Financial Officer male
Yoshitsugu Shitaka Chief Scientific Officer & Senior Managing Executive Officer male
Jun Kono Senior Executive Officer & Head of Japan Commercial
ESG Score History

No data available for this company.

Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend yield history

Dividend history

Earnings history

Earnings reports

Stock splits