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Kyowa Kirin Co., Ltd. (4151.T)

JPY2,667.50 +37.50 (+1.43%)
JP JPX Healthcare Drug Manufacturers - General
Address Otemachi Financial City Grand Cube 100-0004
Tokyo, JP
CEO Abdul Hafeez Mullick
IPO 2000-01-04
ISIN JP3256000005

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Also trades on Other OTC · KYKOF (USD) Tokyo Stock Exchange · 4151.T (JPY)
Description

Operating globally, Kyowa Kirin Co., Ltd. is a pharmaceutical company focused on the discovery, development, manufacturing, and marketing of innovative medical therapies. The company's core areas of expertise span oncology, nephrology, central nervous system disorders, and immunology. Its extensive product portfolio includes established medications such as ABSTRAL, a sublingual fentanyl formulation for managing breakthrough pain in cancer patients; ALLELOCK, an antihistamine for various allergic conditions; and CONIEL, a calcium channel blocker prescribed for hypertension and angina. Kyowa Kirin also provides a range of advanced biological and specialized treatments. These encompass Crysvita, a recombinant human monoclonal IgG1 antibody targeting fibroblast growth factor 23, and blood-related therapies like ESPO (human erythropoietin), NESP (an erythropoiesis stimulating agent), and GRAN (a human colony-stimulating factor). Further products in its lineup address diverse medical needs: G-LASTA/Peglasta/Neulasta for chemotherapy-induced febrile neutropenia; LEUNASE for acute lymphoblastic leukemia; LUMICEF, a biological treatment for moderate to severe plaque psoriasis; Moventig, a mu-opioid receptor antagonist for opioid-induced constipation; Nouriast/Nourianz, an adenosine receptor antagonist for Parkinson's disease; and ORKEDIA, an oral calcimimetics agent. Other significant offerings are PecFent, a nasally administered spray; POTELIGEO, a humanized monoclonal antibody targeting CC chemokine receptor 4; REGPARA for secondary hyperparathyroidism; Romiplate/Nplate, a recombinant protein promoting platelet production; and SANCUSO for managing nausea and vomiting. Beyond its current offerings, Kyowa Kirin is actively involved in pipeline development, notably through a strategic collaboration with Amgen Inc. for the joint development and commercialization of KHK4083. This Phase 3-ready, fully human anti-OX40 monoclonal antibody is being developed to treat atopic dermatitis. Established in Tokyo, Japan, in 1949, the company changed its name from Kyowa Hakko Kirin Co., Ltd. to Kyowa Kirin Co., Ltd. in June 2019. It operates as a subsidiary of Kirin Holdings Company, Limited.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
JPY2,667.50 +37.50 (+1.43%)
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Volume Profile
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Liquidity & share structure
Average Volume
1M
Beta
0.11
Float Shares
229.42M
Free Float %
43.8%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
-2.22% -2.85% -9.14% -9.26% -5.03% -7.26% +8.95% -11.62% -28.15% +17.28% +227.00%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Price Targets & DCF
Current price
2,667.50
DCF (Unlevered) 8,502.74 +218.8%
DCF (Levered) 6,746.94 +152.9%

DCF figures are point estimates: small changes in growth or discount-rate assumptions move them materially. Read them as a reference, not a precise target.

Ratings Trend (MoM) 18% Bullish
Rating 2026-05 Change
Strong Buy 0 0
Buy 2 0
Hold 3 0
Sell 3 0
Strong Sell 3 0
Quality scores
Altman Z-Score
5.89
Safe zone
Piotroski F-Score
5 / 9
Average
MOAT Score
6 / 10
Developing
Composite Rating
A
Overall Score
4 / 5
High
DCF Score
5 / 5
High
ROE Score
3 / 5
Medium
ROA Score
5 / 5
High
D/E Score
3 / 5
Medium
P/E Score
3 / 5
Medium
P/Book Score
4 / 5
High
Operational MOAT
✗ Below peers
  • Revenue growth Drug Manufacturers - General: +6.6%
    +0.3% Q1'26: +13.1% (vs Q1'25)
  • EPS growth Drug Manufacturers - General: +18.2%
    +13.3% Q1'26: +95.2% (vs Q1'25)
  • FCF margin FCF growth · Drug Manufacturers - General: +36.0%
    +11.6% Q1'26: +37.2% (vs Q1'25)
  • EBIT margin Drug Manufacturers - General: +19.4%
    +20.6% Q1'26: +14.5% (vs Q1'25)
  • ROIC Drug Manufacturers - General: +10.2%
    +11.2% Q1'26: +9.0% (vs Q1'25)
  • Share dilution Drug Manufacturers - General: +0.0%
    -1.2% Q1'26: 0.0% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Drug Manufacturers - General: -0.29×
    0.20× Q1'26: 0.22× (vs Q1'25)
Valuation Multiples From To
Price Forecast (3Y) From To
Model
Adjust
P/E
Theoretical Return — If Invested Today

* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.

DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (0.10) × ERP
WACC = 98% × Ke + 2% × Kd (5.9%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Intrinsic value (base): 8,502.06 Current price: 2,667.50
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2015
actual
Dec 2016
actual
Dec 2017
actual
Dec 2018
actual
Dec 2019
actual
Dec 2020
actual
Dec 2021
actual
Dec 2022
actual
Dec 2023
actual
Dec 2024
actual
Dec 2025
actual
Dec 2026
10 Rev. Ana.
11 EPS Ana.
Dec 2027
11 Rev. Ana.
11 EPS Ana.
Dec 2028
10 Rev. Ana.
10 EPS Ana.
Dec 2029
5 Rev. Ana.
4 EPS Ana.
Dec 2030
5 Rev. Ana.
4 EPS Ana.
Revenue
364.32B
est: 362.72B (+0.4%)
347.96B
est: 346.89B (+0.3%)
353.38B
est: 348.20B (+1.5%)
271.51B
est: 341.16B (-20.4%)
305.82B
est: 305.44B (+0.1%)
318.35B
est: 319.02B (-0.2%)
352.25B
est: 350.56B (+0.5%)
398.37B
est: 396.53B (+0.5%)
442.23B
est: 476.00B (-7.1%)
495.56B
est: 490.91B (+0.9%)
496.83B
est: 483.78B (+2.7%)
522.18B
510.15B – 530.52B
+7.9% YoY
538.76B
524.05B – 551.91B
+3.2% YoY
546.25B
544.04B – 548.46B
+1.4% YoY
590.11B
575.24B – 602.06B
+8.0% YoY
581.00B
566.37B – 592.77B
-1.5% YoY
EBITDA
80.32B
est: 82.09B (-2.1%)
75.25B
est: 78.50B (-4.1%)
84.24B
est: 78.80B (+6.9%)
66.65B
est: 77.21B (-13.7%)
72.15B
est: 69.12B (+4.4%)
75.89B
est: 72.20B (+5.1%)
80.61B
est: 79.33B (+1.6%)
100.85B
est: 89.74B (+12.4%)
116.94B
est: 132.59B (-11.8%)
116.65B
est: 136.74B (-14.7%)
128.42B
est: 134.75B (-4.7%)
145.45B
142.10B – 147.77B
+7.9% YoY
150.07B
145.97B – 153.73B
+3.2% YoY
152.15B
151.54B – 152.77B
+1.4% YoY
164.37B
160.23B – 167.70B
+8.0% YoY
161.83B
157.76B – 165.11B
-1.5% YoY
EBIT
43.77B
est: 62.95B (-30.5%)
51.47B
est: 60.21B (-14.5%)
62.21B
est: 60.43B (+2.9%)
50.40B
est: 59.21B (-14.9%)
53.35B
est: 53.01B (+0.6%)
55.42B
est: 55.37B (+0.1%)
61.11B
est: 60.84B (+0.4%)
82.38B
est: 68.82B (+19.7%)
95.84B
est: 107.93B (-11.2%)
91.87B
est: 111.31B (-17.5%)
102.28B
est: 109.69B (-6.8%)
118.40B
115.67B – 120.29B
+7.9% YoY
122.16B
118.82B – 125.14B
+3.2% YoY
123.85B
123.35B – 124.35B
+1.4% YoY
133.80B
130.43B – 136.51B
+8.0% YoY
131.73B
128.41B – 134.40B
-1.5% YoY
Net Income
29.77B
est: 27.06B (+10.0%)
30.45B
est: 19.22B (+58.4%)
42.90B
est: 21.96B (+95.3%)
54.41B
est: 51.49B (+5.7%)
23.25B
est: 64.56B (-64.0%)
47.03B
est: 47.24B (-0.4%)
52.35B
est: 49.97B (+4.8%)
53.57B
est: 58.32B (-8.1%)
81.19B
est: 97.32B (-16.6%)
59.87B
est: 68.12B (-12.1%)
67.04B
est: 54.77B (+22.4%)
77.01B
66.88B – 96.19B
+40.6% YoY
84.14B
65.16B – 96.84B
+9.3% YoY
82.89B
70.25B – 92.41B
-1.5% YoY
86.84B
84.00B – 89.13B
+4.8% YoY
74.24B
71.81B – 76.20B
-14.5% YoY
SGA
105.70B
est: 135.92B (-22.2%)
100.24B
est: 129.98B (-22.9%)
104.61B
est: 130.47B (-19.8%)
110.28B
est: 127.84B (-13.7%)
106.25B
est: 114.45B (-7.2%)
116.53B
est: 119.54B (-2.5%)
135.11B
est: 131.36B (+2.9%)
166.19B
est: 148.58B (+11.8%)
163.08B
est: 170.56B (-4.4%)
155.81B
est: 175.90B (-11.4%)
152.90B
est: 173.35B (-11.8%)
187.11B
182.80B – 190.10B
+7.9% YoY
193.05B
187.78B – 197.76B
+3.2% YoY
195.73B
194.94B – 196.53B
+1.4% YoY
211.45B
206.12B – 215.73B
+8.0% YoY
208.19B
202.94B – 212.40B
-1.5% YoY
EPS
54.40
est: 51.10 (+6.4%)
55.64
est: 36.30 (+53.3%)
78.38
est: 41.47 (+89.0%)
99.40
est: 97.23 (+2.2%)
43.16
est: 121.91 (-64.6%)
87.56
est: 89.20 (-1.8%)
97.43
est: 94.36 (+3.2%)
99.68
est: 110.13 (-9.5%)
151.03
est: 181.65 (-16.9%)
113.06
est: 130.55 (-13.4%)
128.07
est: 104.97 (+22.0%)
154.99
127.76 – 183.76
+47.7% YoY
161.20
124.49 – 184.99
+4.0% YoY
157.18
134.20 – 176.53
-2.5% YoY
165.90
160.47 – 170.27
+5.6% YoY
141.83
137.19 – 145.57
-14.5% YoY
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-08 A 4/5 5/5 3/5 5/5 3/5 3/5 4/5
2026-05-07 A 4/5 5/5 3/5 4/5 3/5 3/5 4/5
2026-05-01 A 4/5 5/5 3/5 5/5 3/5 3/5 4/5
2026-04-30 A 4/5 5/5 3/5 5/5 3/5 3/5 4/5
2026-04-28 A 4/5 5/5 3/5 5/5 3/5 3/5 4/5
2026-04-27 A 4/5 5/5 3/5 5/5 2/5 3/5 4/5
2026-04-24 A 4/5 5/5 3/5 5/5 2/5 3/5 4/5
2026-04-23 A 4/5 5/5 3/5 5/5 2/5 3/5 4/5
2026-04-22 A 4/5 5/5 3/5 5/5 2/5 3/5 4/5
2026-04-21 A 4/5 5/5 3/5 5/5 2/5 3/5 4/5
2026-04-20 A 4/5 5/5 3/5 5/5 2/5 3/5 4/5
2026-04-17 A 4/5 5/5 3/5 5/5 2/5 3/5 4/5
2026-04-16 A 4/5 5/5 3/5 5/5 2/5 3/5 4/5
2026-04-15 A 4/5 5/5 3/5 5/5 2/5 3/5 4/5
2026-04-14 A 4/5 5/5 3/5 5/5 2/5 3/5 4/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
111.53B
OE per share TTM
213.07
Owner's Yield
9.16%
Maintenance CapEx ratio
75.02%
Maint CapEx / Avg PPE
23.7%

Ownership Overview

Ownership breakdown

Ownership breakdown not available.

At a glance
Institutional holders
Total invested
Insider transactions (90d)
0
Beneficial owners (>5%)
0
Beneficial owners (>5%)

No beneficial ownership filings recorded.

Institutional Activity (13F)

Institutional ownership trend

Institutional history not available.

Top institutional holders

Top holders not available.

Insider Activity

Insider Activity — Latest Quarter

No insider activity available.

Insider buys vs sells (history)

Insider history not available.

Recent insider transactions

No recent insider transactions.

Executive team

Top executives
EBIT / Employee
18.04M
Shares Outstanding
523.49M

Executive compensation

Executive compensation (annual)

Executive compensation not available.

CEO compensation breakdown

No CEO compensation history available.

Proxy statements

Proxy statements (DEF 14A)

No proxy statements available for this company yet.

Recent SEC filings

Recent SEC filings

No SEC filings available for this company yet.

Executive team

NameTitleCompensationGender
Masashi Miyamoto Chairman & Chief Executive Officer 157M male
Abdul Hafeez Mullick President, Chief Executive Officer & Representative Director 157M
Hiroki Nakamura Global Corporate Communications Head
Hiroshi Sonekawa Managing Executive Officer, Vice President and Head of Sales & Marketing Division
Katsuyoshi Tsukii Executive Officer, VP & Head of Development Division
Kazuki Nemoto Head of Global Legal
Koichi Nagano Executive Officer and Head of Tokyo Branch - Sales & Marketing Division
Koji Igarashi Chief Financial Officer male
Masahiro Hara Global Procurement Head male
Motohiko Kawaguchi Chief Financial Officer & Managing Executive Officer male
Naohiko Kubo Global Finance Head & Accounting Manager
Nathan Hawes Global Operational & Digital Transformation Head
ESG Score History

No data available for this company.

Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend yield history

Dividend history

Earnings history

Earnings reports

Stock splits