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Hua Medicine (Shanghai) Ltd. (2552.HK)

HKD2.81 +0.12 (+4.46%)
CN HKSE Healthcare Drug Manufacturers - Specialty & Generic
Address Building A
Shanghai, CN
CEO Li Chen
IPO 2018-09-14
ISIN KYG4644K1022

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Also trades on Hong Kong Stock Exchange · 2552.HK (HKD) Other OTC · HUMDF (USD)
Description

Hua Medicine (Shanghai) Ltd., a biopharmaceutical enterprise established in 2011 and headquartered in Beijing, China, specializes in the clinical development of novel therapeutic solutions, with a primary focus on addressing diabetes within the Chinese market. Its lead asset, Dorzagliatin (also known as HMS5552), is an orally administered medication designed for Type 2 Diabetes. The company is also advancing various combination therapies involving Dorzagliatin for T2D, including pairings with Metformin, Sitagliptin, and Empagliflozin, all of which are currently undergoing Phase I clinical trials. Furthermore, Hua Medicine explores the potential of Dorzagliatin in combination with Pioglitazone for Non-alcoholic steatohepatitis (NASH), with GLP-1 for Alzheimer's disease, and for applications in late-stage Type 2 Diabetes and Type 1 Diabetes. Beyond its diabetes pipeline, the company is developing mGLUR5 as a potential treatment for levodopa-induced dyskinesia in Parkinson's disease patients.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
HKD2.81 +0.12 (+4.46%)
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Volume Profile
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Liquidity & share structure
Average Volume
3M
Beta
0.80
Float Shares
601.49M
Free Float %
60.4%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
-3.31% -12.33% -21.49% -14.61% -22.19% -14.61% -3.66% +24.06% -46.87% -68.24% -68.24%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
vs.
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Price Targets & DCF
Current price
2.81
Ratings Trend (MoM) 100% Bullish
Rating 2026-05 Change
Strong Buy 0 0
Buy 2 +1
Hold 0 0
Sell 0 0
Strong Sell 0 0
Quality scores
Altman Z-Score
-1.68
Distress
Piotroski F-Score
4 / 9
Average
MOAT Score
1 / 10
No MOAT
Composite Rating
A-
Overall Score
4 / 5
High
DCF Score
3 / 5
Medium
ROE Score
5 / 5
High
ROA Score
5 / 5
High
D/E Score
2 / 5
Medium
P/E Score
3 / 5
Medium
P/Book Score
2 / 5
Medium
Operational MOAT
✗ Below peers
  • Revenue growth Drug Manufacturers - Specialty & Generic: +6.8%
    +87.7% Q4'25: +4,214.5% (vs Q4'23)
  • EPS growth Drug Manufacturers - Specialty & Generic: +16.5%
    +528.0% Q4'25: +41.6% (vs Q4'23)
  • FCF margin FCF growth · Drug Manufacturers - Specialty & Generic: +32.3%
    -17.3% Q4'25: +10.8% (vs Q4'23)
  • EBIT margin Drug Manufacturers - Specialty & Generic: +13.0%
    -29.4% Q4'25: -28.9% (vs Q4'23)
  • ROIC Drug Manufacturers - Specialty & Generic: +6.5%
    -65.4% Q4'25: -145.0% (vs Q4'23)
  • Share dilution Drug Manufacturers - Specialty & Generic: +0.0%
    +2.3% Q4'25: +7.8% (vs Q4'23)
  • Debt / EBITDA Net debt/EBITDA · Drug Manufacturers - Specialty & Generic: -0.10×
    -2.76× Q4'25: -1.20× (vs Q4'23)
Valuation Multiples From To
Price Forecast (3Y) From To
Model
Adjust
P/E
Theoretical Return — If Invested Today

* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.

DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (0.84) × ERP
WACC = 88% × Ke + 12% × Kd (4.1%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Current price: 2.81
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2022
actual
Dec 2023
actual
Dec 2024
actual
Dec 2025
actual
Dec 2026
1 Rev. Ana.
1 EPS Ana.
Dec 2027
2 Rev. Ana.
2 EPS Ana.
Dec 2028
1 Rev. Ana.
1 EPS Ana.
Dec 2029
1 Rev. Ana.
Revenue
17.60M
est: 505.39M (-96.5%)
76.61M
est: 117.10M (-34.6%)
255.89M
est: 315.12M (-18.8%)
480.18M
est: 479.21M (+0.2%)
913.85M
911.23M – 916.46M
+90.7% YoY
1.37B
1.36B – 1.37B
+49.6% YoY
1.82B
1.82B – 1.83B
+33.3% YoY
2.20B
2.20B – 2.21B
+21.0% YoY
EBITDA
-168.06M
est: -303.24M (+44.6%)
-167.09M
est: -70.26M (-137.8%)
-345.36M
est: -140.42M (-145.9%)
-109.50M
est: -213.54M (+48.7%)
-407.22M
-408.39M – -406.05M
-90.7% YoY
-609.25M
-612.17M – -606.34M
-49.6% YoY
-811.98M
-814.30M – -809.65M
-33.3% YoY
-982.55M
-985.36M – -979.74M
-21.0% YoY
EBIT
-199.84M
est: -303.24M (+34.1%)
-203.33M
est: -70.26M (-189.4%)
-360.31M
est: -144.57M (-149.2%)
-141.13M
est: -219.85M (+35.8%)
-419.26M
-420.46M – -418.06M
-90.7% YoY
-627.27M
-630.27M – -624.26M
-49.6% YoY
-835.98M
-838.37M – -833.59M
-33.3% YoY
-1.01B
-1.01B – -1.01B
-21.0% YoY
Net Income
-203.77M
est: -303.54M (+32.9%)
-211.23M
est: -142.19M (-48.6%)
-250.14M
est: -165.48M (-51.2%)
1.08B
est: 815.52M (+32.2%)
13.07M
13.03M – 13.12M
-98.4% YoY
154.24M
108.87M – 199.60M
+1,079.7% YoY
372.09M
370.70M – 373.47M
+141.2% YoY
— – —
-100.0% YoY
SGA
145.28M
est: 2.95B (-95.1%)
203.90M
est: 682.47M (-70.1%)
269.94M
est: 853.30M (-68.4%)
272.67M
est: 1.30B (-79.0%)
2.47B
2.47B – 2.48B
+90.7% YoY
3.70B
3.68B – 3.72B
+49.6% YoY
4.93B
4.92B – 4.95B
+33.3% YoY
5.97B
5.95B – 5.99B
+21.0% YoY
EPS
-0.21
est: -0.31 (+32.1%)
-0.22
est: -0.14 (-51.8%)
-0.25
est: -0.16 (-51.7%)
1.09
est: 0.81 (+34.2%)
0.01
0.01 – 0.01
-98.4% YoY
0.15
0.11 – 0.20
+1,079.7% YoY
0.37
0.37 – 0.37
+141.2% YoY
— – —
-100.0% YoY
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-29 A- 4/5 3/5 5/5 5/5 2/5 3/5 2/5
2026-05-28 A- 4/5 3/5 5/5 5/5 2/5 3/5 2/5
2026-05-27 A- 4/5 3/5 5/5 5/5 2/5 3/5 2/5
2026-05-26 A- 4/5 3/5 5/5 5/5 2/5 3/5 2/5
2026-05-22 A- 4/5 3/5 5/5 5/5 2/5 3/5 2/5
2026-05-21 A- 4/5 3/5 5/5 5/5 2/5 3/5 2/5
2026-05-20 A- 4/5 3/5 5/5 5/5 2/5 3/5 2/5
2026-05-19 A- 4/5 3/5 5/5 5/5 2/5 3/5 2/5
2026-05-18 A- 4/5 3/5 5/5 5/5 2/5 3/5 2/5
2026-05-15 A- 4/5 3/5 5/5 5/5 2/5 3/5 2/5
2026-05-14 A- 4/5 3/5 5/5 5/5 2/5 3/5 2/5
2026-05-13 A- 4/5 3/5 5/5 5/5 2/5 3/5 2/5
2026-05-12 A- 4/5 3/5 5/5 5/5 2/5 3/5 2/5
2026-05-11 A- 4/5 3/5 5/5 5/5 2/5 3/5 2/5
2026-05-08 A 4/5 3/5 5/5 5/5 2/5 4/5 3/5
2026-05-07 A 4/5 3/5 5/5 5/5 2/5 4/5 3/5
2026-05-06 A 4/5 3/5 5/5 5/5 2/5 4/5 3/5
2026-05-05 A 4/5 3/5 5/5 5/5 2/5 4/5 3/5
2026-05-04 A 4/5 3/5 5/5 5/5 2/5 4/5 3/5
2026-04-30 A- 4/5 3/5 5/5 5/5 2/5 4/5 2/5
2026-04-29 A- 4/5 3/5 5/5 5/5 2/5 4/5 2/5
2026-04-28 A- 4/5 3/5 5/5 5/5 2/5 4/5 2/5
2026-04-27 A- 4/5 3/5 5/5 5/5 1/5 4/5 2/5
2026-04-24 A- 4/5 3/5 5/5 5/5 1/5 4/5 2/5
2026-04-23 A- 4/5 3/5 5/5 5/5 1/5 4/5 2/5
2026-04-22 A- 4/5 3/5 5/5 5/5 1/5 4/5 2/5
2026-04-21 A- 4/5 3/5 5/5 5/5 1/5 3/5 3/5
2026-04-20 A- 4/5 3/5 5/5 5/5 1/5 3/5 3/5
2026-04-17 A- 4/5 3/5 5/5 5/5 1/5 3/5 3/5
2026-04-16 A- 4/5 3/5 5/5 5/5 1/5 3/5 3/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
383.95M
OE per share TTM
0.37
Owner's Yield
13.82%
Maintenance CapEx ratio
Maint CapEx / Avg PPE
102.0%

Ownership Overview

Ownership breakdown

Ownership breakdown not available.

At a glance
Institutional holders
Total invested
Insider transactions (90d)
0
Beneficial owners (>5%)
0
Beneficial owners (>5%)

No beneficial ownership filings recorded.

Institutional Activity (13F)

Institutional ownership trend

Institutional history not available.

Top institutional holders

Top holders not available.

ETF Ownership

Top ETFs holding this stock Held by 9 ETFs in our universe
# ETF Weight Est. AUM exposure TER
1 State Street SPDR S&P Emerging Markets Small Cap ETF EWX 0.01% 105.7K 0.65%
2 Avantis Emerging Markets Equity UCITS ETF USD Acc AVEM.L 0.01% 21.9K 0.35%
3 Avantis Emerging Markets Value ETF AVES 0.01% 114.9K 0.36%
4 State Street SPDR S&P China ETF GXC 0.01% 33.0K 0.59%
5 State Street SPDR Portfolio Emerging Markets ETF SPEM 0.00% 676.5K 0.07%
6 Dimensional World ex U.S. Core Equity 2 ETF DFAX 0.00% 57.2K 0.28%
7 Dimensional - Emerging Core Equity Market ETF DFAE 0.00% 45.8K 0.29%
8 Dimensional - Emerging Markets Core Equity 2 ETF DFEM 0.00% 22.7K 0.39%
9 Avantis Emerging Markets Equity ETF AVEM 0.00% 42.8K 0.33%

Insider Activity

Insider Activity — Latest Quarter

No insider activity available.

Insider buys vs sells (history)

Insider history not available.

Recent insider transactions

No recent insider transactions.

Executive team

Top executives
EBIT / Employee
-840.1K
Shares Outstanding
996.52M

Executive compensation

Executive compensation (annual)

Executive compensation not available.

CEO compensation breakdown

No CEO compensation history available.

Proxy statements

Proxy statements (DEF 14A)

No proxy statements available for this company yet.

Recent SEC filings

Recent SEC filings

No SEC filings available for this company yet.

Executive team

NameTitleCompensationGender
Li Chen Founder, Chief Executive Officer & Executive Director 12M
Chien Cheng Lin Executive Vice President, Chief Strategy Officer & Executive Director 7M male
Yi Zhang Senior Vice President of Pharma Development, Chief Medical Officer – China and Executive Director 5M
Fuxing Tang Chief Technology Officer, Vice President of Chemical Manufacturing Control Department and Head of R&D in USA
Wing Yan Yuen FCIS Company Secretary female
Ying Xie Vice President of Quality Assurance Division & Chief Quality Officer male
Au-Yeung Nelly Company Secretary female
Yu Lu Vice President of Sales & Marketing male
Changhong Li Chief Scientific Officer
Chengde Wang Head of IR male
ESG Score History

No data available for this company.

Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend history

Earnings history

Earnings reports

Stock splits