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State Street SPDR S&P Biotech ETF (XBI)
About this ETF
SPDR Series Trust - State Street SPDR S&P Biotech ETF is an exchange traded fund launched by State Street Global Advisors, Inc. The fund is managed by SSGA Funds Management, Inc. It invests in public equity markets of the United States. It invests in stocks of companies operating across health care, pharmaceuticals, biotechnology and life sciences sectors. The fund invests in growth and value stocks of companies across diversified market capitalization. It seeks to track the performance of the S&P Biotechnology Select Industry Index, by using representative sampling technique. SPDR Series Trust - State Street SPDR S&P Biotech ETF was formed on January 31, 2006 and is domiciled in the United States.
Price
Top 10 holdings
| APOGEE THERAPEUTICS INC APGE | 1.49% |
| KYMERA THERAPEUTICS INC KYMR | 1.41% |
| MODERNA INC MRNA | 1.37% |
| VIKING THERAPEUTICS INC VKTX | 1.29% |
| ERASCA INC ERAS | 1.28% |
| CG ONCOLOGY INC CGON | 1.26% |
| ORUKA THERAPEUTICS INC ORKA | 1.25% |
| PRAXIS PRECISION MEDICINES I PRAX | 1.25% |
| TWIST BIOSCIENCE CORP TWST | 1.23% |
| SPYRE THERAPEUTICS INC SYRE | 1.20% |
Sector mix
Price chart
Returns
| 1 month | +20.56% |
| 3 months | +20.01% |
| 6 months | +25.57% |
| Year to date | +27.40% |
| 1 year | +75.76% |
| 3 years (ann.) | +23.88% |
| 5 years (ann.) | +2.62% |
| 10 years (ann.) | +11.13% |
Risk profile
| Volatility (1y, ann.) | 26.69% |
| Sharpe (1y) | 2.25 |
| Sharpe (3y) | 0.92 |
| Sortino (1y) | 4.02 |
| Max drawdown (1y) | -9.72% |
| Max drawdown (5y) | -54.00% |
| Max drawdown (full) | -63.90% |
| Beta vs S&P 500 (1y) | 1.05 |
| Correlation vs S&P 500 (1y) | 0.49 |
Technical outlook as of 2026-07-13
The Monte Carlo cone is drawn on the price chart above (Forecast overlay); RSI, MACD and the rest of the oscillators live in its indicator panels.
Full holdings
| Constituent | ISIN | Market value | Weight |
|---|---|---|---|
| Loading… | |||
Sector breakdown
Geographic exposure
Cost vs. peers
Comparison universe: 6,948 funds of the same asset class.
Cost impact calculator
Dividend history
Distributing share class Income is paid out to shareholders.
| Ex-date | Payment | Amount |
|---|---|---|
| 2026-06-22 | 2026-06-24 | USD 0.1381 |
| 2025-12-22 | 2025-12-24 | USD 0.4066 |
| 2025-09-22 | 2025-09-24 | USD 0.0267 |
| 2025-06-23 | 2025-06-25 | USD 0.0073 |
| 2025-03-24 | 2025-03-26 | USD 0.0053 |
| 2024-12-23 | 2024-12-26 | USD 0.0027 |
| 2024-09-23 | 2024-09-25 | USD 0.0152 |
| 2024-06-24 | 2024-06-26 | USD 0.1148 |
| 2023-12-18 | 2023-12-21 | USD 0.0139 |
| 2023-06-20 | 2023-06-23 | USD 0.0026 |
| 2021-03-22 | 2021-03-25 | USD 0.0400 |
| 2020-12-21 | 2020-12-24 | USD 0.1760 |
| 2020-09-21 | 2020-09-24 | USD 0.0890 |
| 2020-06-22 | 2020-06-25 | USD 0.0168 |
| 2019-12-20 | 2019-12-26 | USD 0.0009 |
| 2019-09-20 | 2019-09-25 | USD 0.0032 |
| 2018-12-21 | 2018-12-27 | USD 0.0120 |
| 2018-09-21 | 2018-09-26 | USD 0.0730 |
| 2018-06-15 | 2018-06-20 | USD 0.0580 |
| 2018-03-16 | 2018-03-21 | USD 0.0590 |
| 2017-12-15 | 2017-12-26 | USD 0.0350 |
| 2017-09-15 | 2017-09-25 | USD 0.0370 |
| 2017-06-16 | 2017-06-26 | USD 0.1100 |
| 2017-03-17 | 2017-03-27 | USD 0.0200 |
| 2016-12-16 | 2016-12-27 | USD 0.0180 |
| 2016-09-16 | 2016-09-26 | USD 0.0310 |
| 2016-06-17 | 2016-06-27 | USD 0.0460 |
| 2016-03-18 | 2016-03-29 | USD 0.0580 |
| 2015-12-18 | 2015-12-29 | USD 0.1490 |
| 2015-09-18 | 2015-09-28 | USD 0.0500 |
| 2015-06-19 | 2015-06-29 | USD 0.1460 |
| 2015-03-20 | 2015-03-30 | USD 0.0817 |
| 2014-12-19 | 2014-12-30 | USD 0.1637 |
| 2014-09-19 | 2014-09-29 | USD 0.1877 |
| 2014-06-20 | 2014-06-30 | USD 0.2053 |
| 2014-03-21 | 2014-03-31 | USD 0.1110 |
| 2013-12-20 | 2013-12-31 | USD 0.0127 |
| 2013-09-20 | 2013-09-30 | USD 0.0291 |
| 2013-06-21 | 2013-07-01 | USD 0.0173 |
| 2013-03-15 | 2013-03-25 | USD 0.0147 |
Splits
| 2015-09-11 | 3:1 |
ESG profile
Benchmark: average of 4,066 funds of the same asset class with derived ESG data.
Similar ETFs
| Fund | TER | AUM (USD) | Yield (TTM) | Return 1y | Sharpe 1y |
|---|---|---|---|---|---|
| Vanguard Total Stock Market ETF VTI | 0.03% | 2.30T | 1.05% | +19.93% | 1.48 |
| Vanguard S&P 500 ETF VOO | 0.03% | 1.70T | 1.07% | +19.68% | 1.49 |
| iShares Core S&P 500 ETF IVV | 0.03% | 894.38B | 1.09% | +19.68% | 1.49 |
| State Street SPDR S&P 500 ETF SPY | 0.09% | 789.23B | 1.00% | +19.71% | 1.49 |
| SPDR S&P 500 ETF Trust 1557.T | 0.09% | 789.09B | 0.49% | +37.54% | 2.26 |
| State Street SPDR S&P 500 ETF SPY.AX | 0.09% | 788.13B | 1.00% | +11.84% | 1.13 |
| Vanguard Total International Stock ETF VXUS | 0.05% | 652.30B | 2.61% | +20.58% | 1.21 |
| Invesco QQQ Trust, Series 1 QQQ | 0.18% | 481.14B | 0.43% | +28.14% | 1.43 |
| Vanguard Growth ETF VUG | 0.03% | 393.80B | 0.39% | +16.85% | 0.99 |
| Vanguard FTSE Developed Markets ETF VEA | 0.03% | 317.30B | 2.60% | +21.64% | 1.23 |
Cheaper alternatives
No fund of the class reaches 60% portfolio overlap — showing the cheapest funds of the class instead.
| Fund | TER | AUM (USD) | Overlap |
|---|---|---|---|
| Vanguard Small-Cap ETF VB | 0.03% | 182.70B | 4.5% |
| Vanguard Value ETF VTV | 0.03% | 245.00B | 2.7% |
| Invesco QQQ Trust, Series 1 QQQ | 0.18% | 481.14B | 2.6% |
| Vanguard Total Stock Market ETF VTI | 0.03% | 2.30T | 2.0% |
| State Street SPDR Portfolio S&P 500 ETF SPYM | 0.02% | 159.32B | 1.6% |
