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Oruka Therapeutics, Inc. (ORKA)
USD84.56
-2.23 (-2.57%)
US NASDAQ Healthcare Biotechnology
Address
221 Crescent Street Building 23, Suite 105
Menlo Park, MA, US
Menlo Park, MA, US
CEO
Lawrence Otto Klein
Website
orukatx.com
IPO
1997-08-08
CIK 907654 ISIN US6876041087
Also trades on
NASDAQ Capital Market · ABIO (USD)
NASDAQ Global Market · ORKA (USD)
Description
Oruka Therapeutics, Inc. functions as a biotechnology firm primarily dedicated to creating groundbreaking monoclonal antibody therapies. These treatments are designed to address Psoriasis (PsO) along with various other inflammatory and immunological (I&I) conditions. Its current development portfolio includes ORKA-001 and ORKA-002. The company's main operations are based in Menlo Park, CA.
Market Cap & Enterprise Value
Merger & Acquisition History
No mergers or acquisitions recorded for this company.
Technical Outlook
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Signal Summary
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| Indicator | 1D | 1W | 2W | 3W | 1M |
|---|
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
USD84.56
-2.23 (-2.57%)
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Volume Profile
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Liquidity & share structure
Average Volume
2M
Beta
-0.40
Float Shares
26.48M
Free Float %
70.7%
Price Performance
| 1D | 5D | 1M | 3M | 6M | YTD | 1Y | 3Y | 5Y | 10Y | Max |
|---|---|---|---|---|---|---|---|---|---|---|
| -3.08% | -4.83% | -10.14% | +89.50% | +119.38% | +104.32% | +500.68% | +144.59% | +57.34% | -91.42% | -100.00% |
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From
To
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Annual Monthly Returns
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Daily Returns Distribution
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Revenue flow
Revenue by geography
Revenue by segment
From
To
Revenue composition
From
To
By product
By geography
Financial Statements
Select metrics from the tables below to build your comparison.
Income Statement
Balance Sheet
Cash Flow Statement
Key Metrics
Financial Ratios
Employees
Financial Growth (CAGR)
Market Data
Analyst Consensus (9 ratings, all time)
Buy
Price Targets & DCF
Current price
84.56
Low
75.00
-11.3%
Consensus
136.38
+61.3%
Median
135.50
+60.2%
High
200.00
+136.5%
DCF (Unlevered)
0.90
-98.9%
DCF (Levered)
0.99
-98.8%
DCF figures are point estimates: small changes in growth or discount-rate assumptions move them materially. Read them as a reference, not a precise target.
Ratings Trend (MoM)
100% Bullish
| Rating | 2026-05 | Change |
|---|---|---|
| Strong Buy | 2 | 0 |
| Buy | 11 | 0 |
| Hold | 0 | 0 |
| Sell | 0 | 0 |
| Strong Sell | 0 | 0 |
Price Target Summary
| Period | # Analysts | Avg Target |
|---|---|---|
| Last Month | 7 |
145.14
+71.6%
|
| Last Quarter | 9 |
130.44
+54.3%
|
| Last Year | 15 |
99.47
+17.6%
|
| All Time | 18 |
88.44
+4.6%
|
Quality scores
Altman Z-Score
77.82
Safe zone
Piotroski F-Score
1 / 9
Weak
MOAT Score
3 / 10
No MOAT
Composite Rating
C
Overall Score
2 / 5
Medium
DCF Score
2 / 5
Medium
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
4 / 5
High
P/E Score
1 / 5
Low
P/Book Score
1 / 5
Low
Operational MOAT
✗ Below peers
-
Revenue growth Biotechnology: +1.6%—
-
EPS growth Biotechnology: +29.7%+53.7% ★ Q1'26: -16.0% (vs Q1'25)
-
FCF margin FCF growth · Biotechnology: +16.2%—
-
EBIT margin Biotechnology: +0.0%—
-
ROIC Biotechnology: -16.1%-89.2% Q1'26: -146.2% (vs Q1'25)
-
Share dilution Biotechnology: -3.4%+171.7% Q1'26: +32.4% (vs Q1'25)
-
Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×-0.02× Q1'26: -0.01× (vs Q1'25)
Valuation Multiples
From
To
Price Forecast (3Y)
From
To
Theoretical Return — If Invested Today
* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.
Consensus Estimates
| Metric |
Dec 2024 actual |
Dec 2025 actual |
Dec 2026 8 EPS Ana. |
Dec 2027 8 EPS Ana. |
Dec 2028 7 EPS Ana. |
Dec 2029 2 EPS Ana. |
Dec 2030 3 Rev. Ana. 5 EPS Ana. |
|---|---|---|---|---|---|---|---|
| Revenue |
—
|
—
|
—
— – —
|
—
— – —
|
—
— – —
|
—
— – —
|
75.58M
75.58M – 75.58M
|
| EBITDA |
-82.23M
|
-121.97M
|
—
— – —
|
—
— – —
|
—
— – —
|
—
— – —
|
—
— – —
|
| EBIT |
-82.26M
|
-122.05M
|
—
— – —
|
—
— – —
|
—
— – —
|
—
— – —
|
—
— – —
|
| Net Income |
-83.72M
est: -77.43M (-8.1%)
|
-105.43M
est: -94.19M (-11.9%)
|
-102.50M
-120.19M – -84.81M
-8.8% YoY
|
-119.29M
-134.72M – -103.87M
-16.4% YoY
|
-177.91M
-269.46M – -86.35M
-49.1% YoY
|
-194.47M
-194.47M – -194.47M
-9.3% YoY
|
-216.97M
-216.97M – -216.97M
-11.6% YoY
|
| SGA |
13.04M
|
21.33M
|
—
— – —
|
—
— – —
|
—
— – —
|
—
— – —
|
—
— – —
|
| EPS |
-4.99
est: -3.41 (-46.4%)
|
-2.31
est: -2.20 (-4.8%)
|
-2.14
-2.63 – -1.86
+3.0% YoY
|
-2.53
-2.95 – -2.28
-18.2% YoY
|
-3.38
-5.91 – -1.89
-34.0% YoY
|
-4.26
-4.26 – -4.26
-26.0% YoY
|
-4.76
-4.76 – -4.76
-11.6% YoY
|
Recent Grade Changes (3M)
| Date | Firm | Previous | New Grade | Action |
|---|---|---|---|---|
| 2026-05-14 | BTIG | Buy | Buy | Maintain |
| 2026-04-29 | HC Wainwright & Co. | Buy | Buy | Maintain |
| 2026-04-28 | UBS | Buy | Buy | Maintain |
| 2026-04-27 | BTIG | Buy | Buy | Maintain |
| 2026-04-15 | Wedbush | Outperform | Outperform | Maintain |
Historical Ratings (3M)
| Date | Rating | Overall | DCF | ROE | ROA | D/E | P/E | P/B |
|---|---|---|---|---|---|---|---|---|
| 2026-05-15 | C | 2/5 | 2/5 | 1/5 | 1/5 | 4/5 | 1/5 | 1/5 |
| 2026-05-14 | C | 2/5 | 2/5 | 1/5 | 1/5 | 4/5 | 1/5 | 2/5 |
| 2026-05-13 | C | 2/5 | 2/5 | 1/5 | 1/5 | 4/5 | 1/5 | 2/5 |
| 2026-05-12 | C | 2/5 | 2/5 | 1/5 | 1/5 | 4/5 | 1/5 | 2/5 |
| 2026-05-11 | C | 2/5 | 2/5 | 1/5 | 1/5 | 4/5 | 1/5 | 2/5 |
| 2026-05-08 | C | 2/5 | 2/5 | 1/5 | 1/5 | 4/5 | 1/5 | 2/5 |
| 2026-05-07 | C | 2/5 | 2/5 | 1/5 | 1/5 | 4/5 | 1/5 | 2/5 |
| 2026-05-06 | C | 2/5 | 2/5 | 1/5 | 1/5 | 4/5 | 1/5 | 2/5 |
| 2026-05-05 | C | 2/5 | 2/5 | 1/5 | 1/5 | 3/5 | 1/5 | 2/5 |
| 2026-05-04 | C | 2/5 | 2/5 | 1/5 | 1/5 | 3/5 | 1/5 | 2/5 |
| 2026-05-01 | C | 2/5 | 2/5 | 1/5 | 1/5 | 3/5 | 1/5 | 2/5 |
| 2026-04-30 | C | 2/5 | 2/5 | 1/5 | 1/5 | 3/5 | 1/5 | 2/5 |
| 2026-04-29 | C | 2/5 | 2/5 | 1/5 | 1/5 | 3/5 | 1/5 | 2/5 |
| 2026-04-28 | C | 2/5 | 2/5 | 1/5 | 1/5 | 3/5 | 1/5 | 2/5 |
| 2026-04-27 | C | 2/5 | 2/5 | 1/5 | 1/5 | 3/5 | 1/5 | 2/5 |
| 2026-04-24 | C | 2/5 | 2/5 | 1/5 | 1/5 | 3/5 | 1/5 | 2/5 |
| 2026-04-23 | C- | 1/5 | 2/5 | 1/5 | 1/5 | 2/5 | 1/5 | 2/5 |
| 2026-04-22 | C- | 1/5 | 2/5 | 1/5 | 1/5 | 2/5 | 1/5 | 2/5 |
| 2026-04-21 | C | 2/5 | 3/5 | 1/5 | 1/5 | 2/5 | 1/5 | 2/5 |
| 2026-04-20 | C | 2/5 | 3/5 | 1/5 | 1/5 | 2/5 | 1/5 | 2/5 |
| 2026-04-17 | C | 2/5 | 3/5 | 1/5 | 1/5 | 2/5 | 1/5 | 2/5 |
| 2026-04-16 | C | 2/5 | 3/5 | 1/5 | 1/5 | 2/5 | 1/5 | 2/5 |
| 2026-04-15 | C | 2/5 | 3/5 | 1/5 | 1/5 | 2/5 | 1/5 | 2/5 |
Owner Earnings
Owner's Earnings (history)
Owner's Earnings history not available.
Owner alignment
Owner's Earnings TTM
—
OE per share TTM
—
Owner's Yield
—
Maintenance CapEx ratio
—
Maint CapEx / Avg PPE
—
Ownership Overview
Ownership breakdown
At a glance
Institutional holders
182
Total invested
2.57B
Insider transactions (90d)
2
Beneficial owners (>5%)
0
Beneficial owners (>5%)
No beneficial ownership filings recorded.
Institutional Activity (13F)
Institutional ownership trend
From
To
13F snapshot — 2026 Q1
Investors holding
182
+38 vs prev Q
New positions
63
Closed positions
26
Increased
125
Reduced
30
Put/Call ratio
2.13
Calls held
40.4K
Puts held
86.0K
Top institutional holders
| # | Investor | Shares / Δ | Mkt value / Δ | Own% / Δ | Weight% / Δ | Avg px / Perf. | Hold / Status |
|---|---|---|---|---|---|---|---|
| 1 | — | 118.5K +118.5K (+100.0%) | 3.59B +3.6B (+100.0%) | 0.27% +0.269 pp | 3.55% +3.553 pp | USD30.31 +0.0% | 1 qtrs NEW |
| 2 | FMR LLC | 7.26M +3.8K (+0.1%) | 220.09M +80.5M (+57.7%) | 16.48% -0.707 pp | 0.01% +0.004 pp | USD22.54 +34.5% | 6 qtrs — |
| 3 | VR ADVISER, LLC | 4.15M +— (+0.0%) | 125.74M +46.0M (+57.6%) | 9.41% -0.409 pp | 6.21% +1.721 pp | USD21.30 +42.3% | 6 qtrs — |
| 4 | FAIRMOUNT FUNDS MANAGEMENT LLC | 3.71M +— (+0.0%) | 112.31M +41.1M (+57.6%) | 8.41% -0.365 pp | 8.55% +2.137 pp | USD23.81 +27.3% | 6 qtrs — |
| 5 | BLACKROCK, INC. | 3.54M +1.3M (+60.6%) | 107.28M +64.9M (+153.1%) | 8.03% +2.812 pp | 0.00% +0.001 pp | USD20.66 +46.7% | 6 qtrs — |
| 6 | VIKING GLOBAL INVESTORS LP | 2.67M +— (+0.0%) | 80.83M +29.5M (+57.6%) | 6.05% -0.263 pp | 0.21% +0.081 pp | USD19.23 +57.6% | 2 qtrs — |
| 7 | VANGUARD GROUP INC | 2.45M +676.9K (+38.1%) | 74.37M +40.2M (+117.7%) | 5.57% +1.361 pp | 0.00% +0.001 pp | USD21.80 +39.0% | 6 qtrs — |
| 8 | DEEP TRACK CAPITAL, LP | 2.16M -493.3K (-18.6%) | 65.52M +14.5M (+28.3%) | 4.91% -1.381 pp | 1.17% -0.257 pp | USD16.94 +78.9% | 6 qtrs — |
| 9 | RTW INVESTMENTS, LP | 2.06M +112.5K (+5.8%) | 62.38M +25.0M (+66.7%) | 4.67% +0.064 pp | 0.62% +0.164 pp | USD24.59 +23.3% | 6 qtrs — |
| 10 | COMMODORE CAPITAL LP | 1.75M +— (+0.0%) | 53.14M +19.4M (+57.6%) | 3.98% -0.173 pp | 3.54% +1.891 pp | USD23.36 +29.8% | 6 qtrs — |
| 11 | PARADIGM BIOCAPITAL ADVISORS LP | 1.71M +1.7M (+100.0%) | 51.84M +51.8M (+100.0%) | 3.88% +3.881 pp | 1.32% +1.323 pp | USD30.31 +0.0% | 1 qtrs NEW |
| 12 | PERCEPTIVE ADVISORS LLC | 1.48M +208.5K (+16.4%) | 44.75M +20.4M (+83.5%) | 3.35% +0.348 pp | 0.80% +0.094 pp | USD20.79 +45.8% | 2 qtrs — |
| 13 | STATE STREET CORP | 1.38M +731.8K (+112.2%) | 41.94M +29.4M (+234.5%) | 3.14% +1.596 pp | 0.00% +0.001 pp | USD23.03 +31.6% | 5 qtrs — |
| 14 | AVORO CAPITAL ADVISORS LLC | 1.33M +— (+0.0%) | 40.41M +14.8M (+57.6%) | 3.03% -0.131 pp | 0.39% +0.057 pp | USD19.23 +57.6% | 2 qtrs — |
| 15 | BLACKSTONE INC. | 1.17M +315.0K (+37.0%) | 35.32M +19.0M (+116.0%) | 2.64% +0.631 pp | 0.14% +0.074 pp | USD17.78 +70.5% | 5 qtrs — |
| 16 | POLAR CAPITAL HOLDINGS PLC | 978.3K -54.0K (-5.2%) | 29.65M +9.8M (+49.4%) | 2.22% -0.224 pp | 0.11% +0.019 pp | USD15.27 +98.5% | 5 qtrs — |
| 17 | GEODE CAPITAL MANAGEMENT, LLC | 942.5K +252.5K (+36.6%) | 28.57M +15.3M (+115.3%) | 2.14% +0.505 pp | 0.00% +0.001 pp | USD19.29 +57.1% | 6 qtrs — |
| 18 | FRANKLIN RESOURCES INC | 938.4K -127.4K (-12.0%) | 28.44M +7.9M (+38.8%) | 2.13% -0.394 pp | 0.01% +0.002 pp | USD20.60 +47.1% | 6 qtrs — |
| 19 | AFFINITY ASSET ADVISORS, LLC | 802.3K -156.8K (-16.4%) | 24.32M +5.9M (+31.8%) | 1.82% -0.450 pp | 1.39% -0.221 pp | USD19.02 +59.4% | 6 qtrs — |
| 20 | MERCER GLOBAL ADVISORS INC /ADV | 745.3K -107.1K (-12.6%) | 22.59M +6.2M (+37.8%) | 1.69% -0.327 pp | 0.03% +0.007 pp | USD11.21 +170.4% | 3 qtrs — |
| 21 | CITADEL ADVISORS LLC | 726.1K +409.2K (+129.1%) | 22.01M +15.9M (+261.2%) | 1.65% +0.897 pp | 0.00% +0.002 pp | USD25.47 +19.0% | 2 qtrs — |
| 22 | AVIDITY PARTNERS MANAGEMENT LP | 660.4K +— (+0.0%) | 20.02M +7.3M (+57.6%) | 1.50% -0.065 pp | 5.77% +2.884 pp | USD22.05 +37.5% | 6 qtrs — |
| 23 | PRICE T ROWE ASSOCIATES INC /MD/ | 649.3K +22.5K (+3.6%) | 19.68M +7.6M (+63.3%) | 1.47% -0.011 pp | 0.00% +0.001 pp | USD20.40 +48.6% | 6 qtrs — |
| 24 | POINT72 ASSET MANAGEMENT, L.P. | 600.0K -437.0K (-42.1%) | 18.19M -1.8M (-8.8%) | 1.36% -1.094 pp | 0.02% -0.013 pp | USD20.91 +45.0% | 6 qtrs — |
| 25 | WOODLINE PARTNERS LP | 574.6K +223.0 (+0.0%) | 17.41M +6.4M (+57.7%) | 1.30% -0.056 pp | 0.07% +0.016 pp | USD22.82 +32.8% | 6 qtrs — |
| 26 | CORMORANT ASSET MANAGEMENT, LP | 533.3K +— (+0.0%) | 16.17M +5.9M (+57.6%) | 1.21% -0.053 pp | 0.75% +0.040 pp | USD19.23 +57.6% | 2 qtrs — |
| 27 | SYNERGY ASSET MANAGEMENT, LLC | 458.9K +458.9K (+100.0%) | 13.91M +13.9M (+100.0%) | 1.04% +1.042 pp | 1.45% +1.447 pp | USD30.31 +0.0% | 1 qtrs NEW |
| 28 | SR ONE CAPITAL MANAGEMENT, LP | 430.3K +— (+0.0%) | 13.04M +4.8M (+57.6%) | 0.98% -0.042 pp | 1.85% +0.650 pp | USD23.86 +27.0% | 6 qtrs — |
| 29 | CANDRIAM S.C.A. | 400.5K +33.5K (+9.1%) | 12.14M +5.1M (+72.0%) | 0.91% +0.040 pp | 0.06% +0.024 pp | USD17.54 +72.8% | 4 qtrs — |
| 30 | CABLE CAR CAPITAL LLC | 400.0K -100.0K (-20.0%) | 12.12M +2.5M (+26.1%) | 0.91% -0.276 pp | 0.40% -3.718 pp | USD18.42 +64.5% | 6 qtrs — |
| 31 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 329.5K +82.6K (+33.4%) | 9.99M +5.2M (+110.3%) | 0.75% +0.163 pp | 0.00% +0.001 pp | USD20.35 +48.9% | 5 qtrs — |
| 32 | NORTHERN TRUST CORP | 280.9K +61.2K (+27.9%) | 8.51M +4.3M (+101.5%) | 0.64% +0.117 pp | 0.00% +0.001 pp | USD17.09 +77.4% | 5 qtrs — |
| 33 | UBS GROUP AG | 271.0K +184.5K (+213.1%) | 8.21M +6.5M (+393.5%) | 0.62% +0.410 pp | 0.00% +0.001 pp | USD24.78 +22.3% | 5 qtrs — |
| 34 | SOLEUS CAPITAL MANAGEMENT, L.P. | 190.0K +190.0K (+100.0%) | 5.76M +5.8M (+100.0%) | 0.43% +0.431 pp | 0.21% +0.212 pp | USD30.31 +0.0% | 1 qtrs NEW |
| 35 | GREAT POINT PARTNERS LLC | 183.3K +— (+0.0%) | 5.56M +2.0M (+57.6%) | 0.42% -0.018 pp | 1.80% +0.348 pp | USD19.23 +57.6% | 2 qtrs — |
| 36 | BARCLAYS PLC | 173.3K +78.0K (+81.8%) | 5.25M +3.4M (+186.6%) | 0.39% +0.168 pp | 0.00% +0.001 pp | USD23.51 +28.9% | 5 qtrs — |
| 37 | INVESCO LTD. | 143.1K +126.8K (+777.1%) | 4.34M +4.0M (+1,282.4%) | 0.32% +0.286 pp | 0.00% +0.001 pp | USD28.19 +7.5% | 3 qtrs — |
| 38 | BANK OF AMERICA CORP /DE/ | 139.3K +60.3K (+76.3%) | 4.22M +2.7M (+177.9%) | 0.32% +0.129 pp | 0.00% +0.000 pp | USD22.92 +32.2% | 6 qtrs — |
| 39 | LONGAEVA PARTNERS L.P. | 128.1K +128.1K (+100.0%) | 3.88M +3.9M (+100.0%) | 0.29% +0.291 pp | 0.33% +0.326 pp | USD30.31 +0.0% | 1 qtrs NEW |
| 40 | MOODY ALDRICH PARTNERS LLC | 126.8K +126.8K (+100.0%) | 3.84M +3.8M (+100.0%) | 0.29% +0.288 pp | 0.72% +0.717 pp | USD30.31 +0.0% | 1 qtrs NEW |
| 41 | MORGAN STANLEY | 122.2K -12.6K (-9.4%) | 3.70M +1.1M (+42.8%) | 0.28% -0.042 pp | 0.00% +0.000 pp | USD17.94 +69.0% | 6 qtrs — |
| 42 | DEUTSCHE BANK AG\ | 119.3K +97.2K (+439.5%) | 3.62M +3.2M (+750.3%) | 0.27% +0.218 pp | 0.00% +0.001 pp | USD26.95 +12.5% | 3 qtrs — |
| 43 | SIO CAPITAL MANAGEMENT, LLC | 118.1K +118.1K (+100.0%) | 3.58M +3.6M (+100.0%) | 0.27% +0.268 pp | 0.56% +0.563 pp | USD30.31 +0.0% | 1 qtrs NEW |
| 44 | BANK OF NEW YORK MELLON CORP | 114.2K +43.5K (+61.6%) | 3.46M +2.1M (+154.8%) | 0.26% +0.092 pp | 0.00% +0.000 pp | USD18.99 +59.6% | 3 qtrs — |
| 45 | ALYESKA INVESTMENT GROUP, L.P. | 100.0K +100.0K (+100.0%) | 3.03M +3.0M (+100.0%) | 0.23% +0.227 pp | 0.01% +0.009 pp | USD30.31 +0.0% | 1 qtrs NEW |
| 46 | GOLDMAN SACHS GROUP INC | 93.0K +73.2K (+370.3%) | 2.82M +2.4M (+641.2%) | 0.21% +0.164 pp | 0.00% +0.000 pp | USD26.05 +16.4% | 4 qtrs — |
| 47 | NUVEEN, LLC | 86.3K +51.0K (+144.5%) | 2.62M +1.9M (+285.4%) | 0.20% +0.112 pp | 0.00% +0.001 pp | USD22.50 +34.7% | 3 qtrs — |
| 48 | BRAIDWELL LP | 84.8K -1.3M (-93.9%) | 2.57M -24.0M (-90.3%) | 0.19% -3.081 pp | 0.08% -0.707 pp | USD18.60 +63.0% | 6 qtrs — |
| 49 | WELLINGTON MANAGEMENT GROUP LLP | 84.7K -6.4K (-7.0%) | 2.57M +816.0K (+46.6%) | 0.19% -0.023 pp | 0.00% +0.000 pp | USD19.23 +57.6% | 6 qtrs — |
| 50 | SECURE ASSET MANAGEMENT, LLC | 81.7K +81.7K (+100.0%) | 2.48M +2.5M (+100.0%) | 0.19% +0.185 pp | 0.39% +0.387 pp | USD30.31 +0.0% | 1 qtrs NEW |
| 51 | TD ASSET MANAGEMENT INC | 79.9K +34.0K (+74.2%) | 2.42M +1.5M (+174.5%) | 0.18% +0.073 pp | 0.00% +0.001 pp | USD26.98 +12.3% | 6 qtrs — |
| 52 | D. E. SHAW & CO., INC. | 76.4K -19.0K (-19.9%) | 2.32M +481.3K (+26.2%) | 0.17% -0.053 pp | 0.00% +0.000 pp | USD13.54 +123.9% | 3 qtrs — |
| 53 | ABRDN PLC | 75.7K +— (+0.0%) | 2.29M +838.5K (+57.6%) | 0.17% -0.008 pp | 0.00% +0.001 pp | USD11.21 +170.4% | 3 qtrs — |
| 54 | B GROUP, INC. | 75.0K +— (+0.0%) | 2.27M +831.0K (+57.6%) | 0.17% -0.007 pp | 1.68% +0.618 pp | USD12.91 +134.8% | 5 qtrs — |
| 55 | PALO ALTO INVESTORS LP | 60.0K +— (+0.0%) | 1.82M +1.0M (+129.8%) | 0.14% -0.006 pp | 0.25% +0.107 pp | USD19.23 +57.6% | 2 qtrs — |
| 56 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 61.4K +9.5K (+18.2%) | 1.80M +802.6K (+80.4%) | 0.14% +0.016 pp | 0.00% +0.001 pp | USD23.16 +30.9% | 6 qtrs — |
| 57 | MILLENNIUM MANAGEMENT LLC | 58.7K +58.7K (+100.0%) | 1.78M +1.8M (+100.0%) | 0.13% +0.133 pp | 0.00% +0.001 pp | USD30.31 +0.0% | 5 qtrs — |
| 58 | AMERICAN CENTURY COMPANIES INC | 57.1K +23.0K (+67.3%) | 1.73M +1.1M (+163.8%) | 0.13% +0.049 pp | 0.00% +0.001 pp | USD23.69 +27.9% | 2 qtrs — |
| 59 | KENNEDY CAPITAL MANAGEMENT LLC | 48.7K +420.0 (+0.9%) | 1.48M +547.5K (+59.0%) | 0.11% -0.004 pp | 0.03% +0.011 pp | USD18.76 +61.6% | 5 qtrs — |
| 60 | WELLS FARGO & COMPANY/MN | 43.3K +22.4K (+107.4%) | 1.31M +910.2K (+226.9%) | 0.10% +0.049 pp | 0.00% +0.000 pp | USD21.73 +39.5% | 3 qtrs — |
| 61 | SWISS NATIONAL BANK | 43.0K +43.0K (+100.0%) | 1.30M +1.3M (+100.0%) | 0.10% +0.098 pp | 0.00% +0.001 pp | USD30.31 +0.0% | 1 qtrs NEW |
| 62 | VOYA INVESTMENT MANAGEMENT LLC | 42.5K +42.5K (+100.0%) | 1.29M +1.3M (+100.0%) | 0.10% +0.097 pp | 0.00% +0.001 pp | USD30.31 +0.0% | 1 qtrs NEW |
| 63 | RHUMBLINE ADVISERS | 41.0K +10.7K (+35.2%) | 1.24M +660.0K (+113.2%) | 0.09% +0.021 pp | 0.00% +0.001 pp | USD16.53 +83.4% | 3 qtrs — |
| 64 | ALPS ADVISORS INC | 39.8K +39.8K (+100.0%) | 1.20M +1.2M (+100.0%) | 0.09% +0.090 pp | 0.01% +0.007 pp | USD30.31 +0.0% | 1 qtrs NEW |
| 65 | RAFFERTY ASSET MANAGEMENT, LLC | 38.5K +25.7K (+201.0%) | 1.17M +920.6K (+374.4%) | 0.09% +0.057 pp | 0.00% +0.003 pp | USD26.63 +13.8% | 2 qtrs — |
| 66 | ALLIANCEBERNSTEIN L.P. | 37.8K +37.8K (+100.0%) | 1.15M +1.1M (+100.0%) | 0.09% +0.086 pp | 0.00% +0.000 pp | USD30.31 +0.0% | 1 qtrs NEW |
| 67 | VERITION FUND MANAGEMENT LLC | 35.7K +35.7K (+100.0%) | 1.08M +1.1M (+100.0%) | 0.08% +0.081 pp | 0.00% +0.004 pp | USD30.31 +0.0% | 1 qtrs NEW |
| 68 | FINANCIAL ENHANCEMENT GROUP LLC | 31.3K -1.5K (-4.6%) | 1.08M +336.2K (+45.3%) | 0.07% -0.007 pp | 0.14% +0.041 pp | USD19.23 +57.6% | 2 qtrs — |
| 69 | TWO SIGMA INVESTMENTS, LP | 28.6K +— (+0.0%) | 865.8K +316.5K (+57.6%) | 0.06% -0.003 pp | 0.00% +0.000 pp | USD10.57 +186.8% | 4 qtrs — |
| 70 | SCHRODER INVESTMENT MANAGEMENT GROUP | 29.2K +— (+0.0%) | 849.8K +286.9K (+51.0%) | 0.07% -0.003 pp | 0.00% +0.000 pp | USD19.23 +57.6% | 2 qtrs — |
| 71 | SQUAREPOINT OPS LLC | 27.7K +27.7K (+100.0%) | 838.7K +838.7K (+100.0%) | 0.06% +0.063 pp | 0.00% +0.001 pp | USD30.31 +0.0% | 1 qtrs NEW |
| 72 | VOLEON CAPITAL MANAGEMENT LP | 23.5K +23.5K (+100.0%) | 713.7K +713.7K (+100.0%) | 0.05% +0.053 pp | 0.02% +0.015 pp | USD30.31 +0.0% | 1 qtrs NEW |
| 73 | STATE OF WISCONSIN INVESTMENT BOARD | 23.0K +23.0K (+100.0%) | 696.2K +696.2K (+100.0%) | 0.05% +0.052 pp | 0.00% +0.002 pp | USD30.31 +0.0% | 1 qtrs NEW |
| 74 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 21.7K +20.0K (+1,175.5%) | 656.5K +623.8K (+1,910.4%) | 0.05% +0.045 pp | 0.00% +0.001 pp | USD28.81 +5.2% | 3 qtrs — |
| 75 | METLIFE INVESTMENT MANAGEMENT, LLC | 21.4K +4.8K (+29.4%) | 647.5K +329.9K (+103.9%) | 0.05% +0.009 pp | 0.00% +0.002 pp | USD15.55 +94.9% | 3 qtrs — |
| 76 | ADAR1 CAPITAL MANAGEMENT, LLC | 20.8K +— (+0.0%) | 631.7K +230.9K (+57.6%) | 0.05% -0.002 pp | 0.05% +0.009 pp | USD10.33 +193.4% | 6 qtrs — |
| 77 | JPMORGAN CHASE & CO | 20.4K +5.9K (+41.0%) | 618.8K +340.4K (+122.3%) | 0.05% +0.012 pp | 0.00% +0.000 pp | USD17.63 +71.9% | 5 qtrs — |
| 78 | MIRAE ASSET GLOBAL ETFS HOLDINGS LTD. | 20.2K +7.0K (+53.3%) | 608.1K +355.4K (+140.6%) | 0.05% +0.015 pp | 0.00% +0.001 pp | USD17.85 +69.8% | 3 qtrs — |
| 79 | HUDSON BAY CAPITAL MANAGEMENT LP | 20.0K +20.0K (+100.0%) | 606.2K +606.2K (+100.0%) | 0.05% +0.045 pp | 0.00% +0.002 pp | USD30.31 +0.0% | 1 qtrs NEW |
| 80 | GLENMEDE TRUST CO NA | 19.5K +19.5K (+100.0%) | 590.6K +590.6K (+100.0%) | 0.04% +0.044 pp | 0.00% +0.003 pp | USD30.31 +0.0% | 1 qtrs NEW |
| 81 | LEGAL & GENERAL GROUP PLC | 18.7K +16.3K (+656.7%) | 568.1K +520.5K (+1,092.7%) | 0.04% +0.037 pp | 0.00% +0.000 pp | USD27.79 +9.1% | 3 qtrs — |
| 82 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 17.2K +4.3K (+33.3%) | 521.3K +273.3K (+110.2%) | 0.04% +0.009 pp | 0.00% +0.000 pp | USD22.00 +37.8% | 2 qtrs — |
| 83 | BROOKWOOD INVESTMENT GROUP LLC | 16.6K +16.6K (+100.0%) | 502.2K +502.2K (+100.0%) | 0.04% +0.038 pp | 0.06% +0.060 pp | USD30.31 +0.0% | 1 qtrs NEW |
| 84 | EMPIRICAL FINANCIAL SERVICES, LLC D.B.A. EMPIRICAL WEALTH MANAGEMENT | 15.4K +— (+0.0%) | 467.0K +170.7K (+57.6%) | 0.04% -0.002 pp | 0.01% +0.002 pp | USD19.23 +57.6% | 2 qtrs — |
| 85 | ENVESTNET ASSET MANAGEMENT INC | 15.2K +15.2K (+100.0%) | 462.1K +462.1K (+100.0%) | 0.03% +0.035 pp | 0.00% +0.000 pp | USD30.31 +0.0% | 1 qtrs NEW |
| 86 | QUEST PARTNERS LLC | 14.9K +4.1K (+38.5%) | 451.6K +244.7K (+118.3%) | 0.03% +0.008 pp | 0.03% +0.012 pp | USD15.83 +91.5% | 4 qtrs — |
| 87 | INTECH INVESTMENT MANAGEMENT LLC | 14.8K +2.3K (+18.4%) | 449.0K +208.5K (+86.7%) | 0.03% +0.004 pp | 0.00% +0.002 pp | USD14.18 +113.8% | 3 qtrs — |
| 88 | PROFUND ADVISORS LLC | 14.6K +14.6K (+100.0%) | 443.2K +443.2K (+100.0%) | 0.03% +0.033 pp | 0.01% +0.014 pp | USD30.31 +0.0% | 1 qtrs NEW |
| 89 | UBS ASSET MANAGEMENT AMERICAS INC | 14.2K +14.2K (+100.0%) | 431.7K +431.7K (+100.0%) | 0.03% +0.032 pp | 0.00% +0.000 pp | USD30.31 +0.0% | 1 qtrs NEW |
| 90 | RESOLUTE CAPITAL ASSET PARTNERS LLC | 12.5K -62.5K (-83.3%) | 378.9K -1.1M (-73.7%) | 0.03% -0.149 pp | 0.18% -0.571 pp | USD19.23 +57.6% | 2 qtrs — |
| 91 | JANUS HENDERSON GROUP PLC | 12.1K +12.1K (+100.0%) | 366.8K +366.8K (+100.0%) | 0.03% +0.028 pp | 0.00% +0.000 pp | USD30.31 +0.0% | 1 qtrs NEW |
| 92 | ALPHACENTRIC ADVISORS LLC | 10.9K +10.9K (+100.0%) | 329.8K +329.8K (+100.0%) | 0.02% +0.025 pp | 0.33% +0.329 pp | USD30.31 +0.0% | 1 qtrs NEW |
| 93 | ALTFEST L J & CO INC | 10.9K -2.4K (-18.4%) | 329.1K +73.4K (+28.7%) | 0.02% -0.007 pp | 0.04% +0.008 pp | USD19.23 +57.6% | 2 qtrs — |
| 94 | ALLIANZ ASSET MANAGEMENT GMBH | 10.3K +10.3K (+100.0%) | 312.2K +312.2K (+100.0%) | 0.02% +0.023 pp | 0.00% +0.000 pp | USD30.31 +0.0% | 1 qtrs NEW |
| 95 | POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY | 10.2K +2.8K (+38.7%) | 309.4K +167.9K (+118.6%) | 0.02% +0.006 pp | 0.00% +0.001 pp | USD17.52 +73.0% | 3 qtrs — |
| 96 | CITIGROUP INC | 9.8K +6.5K (+191.5%) | 297.9K +233.1K (+359.5%) | 0.02% +0.014 pp | 0.00% +0.000 pp | USD24.48 +23.8% | 6 qtrs — |
| 97 | SEI INVESTMENTS CO | 9.7K +9.7K (+100.0%) | 293.3K +293.3K (+100.0%) | 0.02% +0.022 pp | 0.00% +0.000 pp | USD30.31 +0.0% | 1 qtrs NEW |
| 98 | BREVAN HOWARD CAPITAL MANAGEMENT LP | 9.4K +9.4K (+100.0%) | 285.4K +285.4K (+100.0%) | 0.02% +0.021 pp | 0.00% +0.003 pp | USD30.31 +0.0% | 1 qtrs NEW |
Ownership breakdown by holder
Insider Activity
Insider Activity — Latest Quarter
Ratio by transactions
0.29
Bearish
Ratio by volume
0.50
Neutral
Buys
5
Sells
17
Shares acquired
19.0K
Shares disposed
38.0K
Cash buys
—
Cash sales
12.00
Net activity
-19,000
Insider buys vs sells (history)
From
To
Recent insider transactions
From
To
| Date | Person | Role | Transaction | A/D | Security | Shares | Price | Value | Owned after | D/I | Filing |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026-05-15 | Goncalves Joana | Officer | M-Exempt | D | Employee Stock Option (right to buy) | 3,500 | 6.84 | 23.9K | 207,563 | D | ↗ |
| 2026-05-01 | Sandler Laura Lee | Officer | S-Sale | D | Common Stock | 300 | 65.10 | 19.5K | 237,684 | D | ↗ |
| 2026-04-15 | Goncalves Joana | Officer | M-Exempt | D | Employee Stock Option (right to buy) | 3,500 | 6.84 | 23.9K | 211,063 | D | ↗ |
| 2026-03-16 | Sandler Laura Lee | Officer | S-Sale | D | Common Stock | 600 | 41.30 | 24.8K | 236,984 | D | ↗ |
| 2026-03-16 | Quinlan Paul T | Officer | S-Sale | D | Common Stock | 733 | 41.30 | 30.3K | 31,767 | D | ↗ |
| 2026-03-16 | Klein Lawrence Otto | Director / Officer | S-Sale | D | Common Stock | 1,729 | 41.30 | 71.4K | 927,309 | D | ↗ |
| 2026-03-16 | Goncalves Joana | Officer | M-Exempt | A | Common Stock | 3,500 | 7.80 | 27.3K | 41,018 | D | ↗ |
| 2026-03-16 | Agarwal Arjun | Officer | S-Sale | D | Common Stock | 395 | 41.30 | 16.3K | 18,863 | D | ↗ |
| 2026-03-02 | Sandler Laura Lee | Officer | M-Exempt | A | Common Stock | 5,000 | 7.80 | 39.0K | 242,584 | D | ↗ |
| 2026-02-17 | Goncalves Joana | Officer | M-Exempt | A | Common Stock | 3,500 | 7.80 | 27.3K | 41,018 | D | ↗ |
| 2026-01-23 | Sandler Laura Lee | Officer | A-Award | A | Employee Stock Option (right to buy) | 130,000 | 34.39 | 4.47M | 130,000 | D | ↗ |
| 2026-01-23 | Quinlan Paul T | Officer | A-Award | A | Common Stock | 32,500 | 0.00 | — | 32,500 | D | ↗ |
| 2026-01-23 | Klein Lawrence Otto | Director / Officer | A-Award | A | Employee Stock Option (right to buy) | 306,700 | 34.39 | 10.55M | 306,700 | D | ↗ |
| 2026-01-23 | Goncalves Joana | Officer | A-Award | A | Common Stock | 32,500 | 0.00 | — | 34,018 | D | ↗ |
| 2026-01-23 | Dambkowski Carl | Director | J-Other | A | Common Stock | 116,483 | 0.00 | — | 116,483 | D | ↗ |
| 2026-01-23 | Agarwal Arjun | Officer | A-Award | A | Common Stock | 17,500 | 0.00 | — | 19,258 | D | ↗ |
| 2026-01-15 | Goncalves Joana | Officer | S-Sale | D | Common Stock | 4,381 | 31.56 | 138.3K | 4,137 | D | ↗ |
| 2026-01-02 | Sandler Laura Lee | Officer | M-Exempt | A | Common Stock | 5,000 | 7.80 | 39.0K | 218,084 | D | ↗ |
| 2025-12-19 | Goncalves Joana | Officer | M-Exempt | D | Employee Stock Option (right to buy) | 3,500 | 6.84 | 23.9K | 225,063 | D | ↗ |
| 2025-12-11 | Martin Christopher Nathan | Director | A-Award | A | Stock Option (right to buy) | 35,000 | 30.21 | 1.06M | 35,000 | D | ↗ |
| 2025-09-17 | Fairmount Funds Management LLC | Director / 10% Owner | A-Award | A | Common Stock | 333,340 | 15.00 | 5.00M | 1,131,954 | I | ↗ |
| 2025-07-01 | Sandler Laura Lee | Officer | A-Award | A | Employee Stock Option (right to buy) | 25,000 | 11.80 | 295.0K | 25,000 | D | ↗ |
| 2025-06-02 | Turtle Cameron | Director | A-Award | A | Stock Option (right to buy) | 17,500 | 11.77 | 206.0K | 17,500 | D | ↗ |
| 2025-06-02 | Kulkarni Samarth | Director | A-Award | A | Stock Option (right to buy) | 17,500 | 11.77 | 206.0K | 17,500 | D | ↗ |
| 2025-06-02 | Fairmount Funds Management LLC | Director / 10% Owner | A-Award | A | Stock Option (Right to Buy) | 17,500 | 11.77 | 206.0K | 17,500 | I | ↗ |
| 2025-06-02 | Dambkowski Carl | Director | A-Award | A | Stock Option (right to buy) | 17,500 | 11.77 | 206.0K | 17,500 | D | ↗ |
| 2025-06-02 | BALL KRISTINE M | Director | A-Award | A | Stock Option (right to buy) | 17,500 | 11.77 | 206.0K | 17,500 | D | ↗ |
| 2025-02-14 | Venrock Healthcare Capital Partners III, L.P. | 10% Owner | P-Purchase | A | Common Stock | 88,794 | 11.44 | 1.02M | 4,148,428 | I | ↗ |
| 2025-02-13 | Venrock Healthcare Capital Partners III, L.P. | 10% Owner | P-Purchase | A | Common Stock | 14,950 | 11.63 | 173.9K | 4,059,634 | I | ↗ |
| 2025-02-12 | Venrock Healthcare Capital Partners III, L.P. | 10% Owner | P-Purchase | A | Common Stock | 8,971 | 11.86 | 106.4K | 4,044,684 | I | ↗ |
| 2025-02-11 | Venrock Healthcare Capital Partners III, L.P. | 10% Owner | P-Purchase | A | Common Stock | 9,593 | 10.95 | 105.0K | 4,035,713 | I | ↗ |
| 2025-02-10 | Venrock Healthcare Capital Partners III, L.P. | 10% Owner | — | — | Pre-Funded Warrants (Right to Buy) | 300,000 | 0.00 | 300.00 | 0 | I | ↗ |
| 2025-01-22 | Quinlan Paul T | Officer | A-Award | A | Employee Stock Option (right to buy) | 162,500 | 12.50 | 2.03M | 162,500 | D | ↗ |
| 2025-01-22 | Klein Lawrence Otto | Director / Officer | A-Award | A | Employee Stock Option (right to buy) | 230,000 | 12.50 | 2.88M | 230,000 | D | ↗ |
| 2025-01-22 | Goncalves Joana | Officer | A-Award | A | Employee Stock Option (right to buy) | 162,500 | 12.50 | 2.03M | 162,500 | D | ↗ |
| 2025-01-22 | Agarwal Arjun | Officer | A-Award | A | Employee Stock Option (right to buy) | 120,000 | 12.50 | 1.50M | 120,000 | D | ↗ |
| 2024-11-19 | Fairmount Funds Management LLC | Director / 10% Owner | M-Exempt | A | Common Stock | 160,000 | 0.00 | 160.00 | 798,614 | I | ↗ |
| 2024-09-11 | Fairmount Funds Management LLC | Director / 10% Owner | A-Award | A | Common Stock | 275,000 | 23.00 | 6.33M | 638,614 | — | ↗ |
| 2024-08-29 | Turtle Cameron | Director | — | D | Warrant (Right to Buy) | 9,048 | 7.80 | 70.6K | 0 | — | ↗ |
| 2024-08-29 | Quinlan Paul T | Officer | — | D | Warrant (Right to Buy) | 99,996 | 7.80 | 780.0K | 0 | — | ↗ |
| 2024-08-29 | Kulkarni Samarth | Director | — | D | Stock Option (Right to Buy) | 57,140 | 5.16 | 294.8K | 0 | — | ↗ |
| 2024-08-29 | Klein Lawrence Otto | Director / Officer | — | D | Common Stock | 0 | 0.00 | — | 852,338 | — | ↗ |
| 2024-08-29 | Goncalves Joana | Officer | — | D | Warrant (Right to Buy) | 199,992 | 7.80 | 1.56M | 0 | — | ↗ |
| 2024-08-29 | Fairmount Funds Management LLC | Director / 10% Owner | — | I | Pre-funded Warrant | 5,297,664 | 0.00 | 5.3K | 0 | — | ↗ |
| 2024-08-29 | Dambkowski Carl | Director | — | D | Warrant (Right to Buy) | 22,856 | 7.80 | 178.3K | 0 | — | ↗ |
| 2024-08-29 | BALL KRISTINE M | Director | — | D | Stock Option (Right to Buy) | 71,426 | 6.84 | 488.6K | 0 | — | ↗ |
| 2024-08-29 | Agarwal Arjun | Officer | — | D | Stock Option (Right to Buy) | 128,566 | 5.16 | 663.4K | 0 | — | ↗ |
Executive team
Top executives
Shares Outstanding
37.45M
Executive compensation
Executive compensation (annual)
Executive compensation not available.
CEO compensation breakdown
No CEO compensation history available.
Proxy statements
Proxy statements (DEF 14A)
No proxy statements available for this company yet.
Recent SEC filings
Recent SEC filings
No SEC filings available for this company yet.
Executive team
| Name | Title | Compensation | Gender |
|---|---|---|---|
| Lawrence Otto Klein | President, Chief Executive Officer & Director | 1M | — |
| Paul T. Quinlan | General Counsel & Secretary | 731.0K | male |
| Joana Goncalves | Chief Medical Officer | 731.0K | — |
| Laura Sandler | Chief Operating Officer | — | female |
| Alan Lada | VP of IR & Capital Markets | — | male |
| Rajiv Panwar | Senior VP and Head of Chemistry, Manufacturing & Controls | — | — |
| Arjun Agarwal | Senior Vice President of Finance & Treasurer | — | male |
| Christopher Finch | Senior VP and Head of Business Development & Strategy | — | male |
ESG Score History
No data available for this company.
Senate Trading Activity
No Senate trading activity found for this company.
House Trading Activity
No House trading activity found for this company.
Market share among peers
Peer comparison — filtered group (TTM)
Your opinion
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Community Opinion for ORKA
Short-term intention
Target Price Distribution
These are community opinions and do not constitute buy or sell advice to act on. The results shown are based on aggregated opinions and are not an investment recommendation, nor do they intend to influence any investment decision.
