Invesco Biotechnology & Genome ETF (PBE)
About this ETF
The Invesco Biotechnology & Genome ETF (PBE) seeks to replicate the performance of the Dynamic Biotech & Genome Intellidex Index. This fund typically allocates a minimum of 90% of its total assets to the securities comprising the underlying index. The Index is constructed to achieve capital appreciation by thoroughly evaluating companies based on several investment criteria, including their price momentum, earnings growth, overall quality, management decisions, and valuation. It consists of 30 U.S.-based companies within the biotechnology and genome sectors. These companies are primarily involved in the research, development, manufacture, and distribution of various biotechnological products, services, and processes, or they are businesses that stand to gain significantly from scientific and technological breakthroughs in biotechnology and genetic engineering. Both the…
Price
Top 10 holdings
| Vertex Pharmaceuticals Inc VRTX | 4.97% |
| Amgen Inc AMGN | 4.83% |
| Royalty Pharma PLC RPRX | 4.68% |
| Regeneron Pharmaceuticals Inc REGN | 4.68% |
| Biogen Inc BIIB | 4.61% |
| Alnylam Pharmaceuticals Inc ALNY | 4.52% |
| Gilead Sciences Inc GILD | 4.34% |
| United Therapeutics Corp UTHR | 4.22% |
| Bio-Techne Corp TECH | 3.62% |
| Vericel Corp VCEL | 3.27% |
Sector mix
Price chart
Returns
| 1 month | +8.62% |
| 3 months | +14.87% |
| 6 months | +7.53% |
| Year to date | +10.24% |
| 1 year | +34.54% |
| 3 years (ann.) | +14.68% |
| 5 years (ann.) | +3.23% |
| 10 years (ann.) | +9.37% |
Risk profile
| Volatility (1y, ann.) | 19.06% |
| Sharpe (1y) | 1.65 |
| Sharpe (3y) | 0.78 |
| Sortino (1y) | 3.06 |
| Max drawdown (1y) | -11.82% |
| Max drawdown (5y) | -34.71% |
| Max drawdown (full) | -45.69% |
| Beta vs S&P 500 (1y) | 0.66 |
| Correlation vs S&P 500 (1y) | 0.43 |
Technical outlook as of 2026-07-13
The Monte Carlo cone is drawn on the price chart above (Forecast overlay); RSI, MACD and the rest of the oscillators live in its indicator panels.
Full holdings
| Constituent | ISIN | Market value | Weight |
|---|---|---|---|
| Loading… | |||
Sector breakdown
Geographic exposure
Cost vs. peers
Comparison universe: 6,948 funds of the same asset class.
Cost impact calculator
Dividend history
Distributing share class Income is paid out to shareholders.
| Ex-date | Payment | Amount |
|---|---|---|
| 2026-06-22 | 2026-06-26 | USD 0.8106 |
| 2026-03-23 | 2026-03-27 | USD 0.0824 |
| 2025-12-22 | 2025-12-26 | USD 0.4197 |
| 2025-09-22 | 2025-09-26 | USD 0.2341 |
| 2025-06-23 | 2025-06-27 | USD 0.1305 |
| 2025-03-24 | 2025-03-28 | USD 0.0341 |
| 2024-06-24 | 2024-06-28 | USD 0.0082 |
| 2024-03-18 | 2024-03-22 | USD 0.0242 |
| 2023-06-20 | 2023-06-23 | USD 0.0141 |
| 2020-03-23 | 2020-03-31 | USD 0.0290 |
| 2018-09-24 | 2018-09-28 | USD 0.0021 |
| 2017-06-16 | 2017-06-30 | USD 0.2153 |
| 2017-03-17 | 2017-03-31 | USD 0.0555 |
| 2016-12-16 | 2016-12-30 | USD 0.1208 |
| 2016-09-16 | 2016-09-30 | USD 0.0283 |
| 2015-12-18 | 2015-12-31 | USD 0.3082 |
| 2015-09-18 | 2015-09-30 | USD 0.1366 |
| 2015-06-19 | 2015-06-30 | USD 0.1227 |
| 2014-09-19 | 2014-09-30 | USD 0.0429 |
| 2014-06-20 | 2014-06-30 | USD 0.2340 |
| 2009-12-18 | 2009-12-31 | USD 0.0755 |
ESG profile
Benchmark: average of 4,066 funds of the same asset class with derived ESG data.
Similar ETFs
| Fund | TER | AUM (USD) | Yield (TTM) | Return 1y | Sharpe 1y |
|---|---|---|---|---|---|
| Vanguard Total Stock Market ETF VTI | 0.03% | 2.30T | 1.05% | +19.93% | 1.48 |
| Vanguard S&P 500 ETF VOO | 0.03% | 1.70T | 1.07% | +19.68% | 1.49 |
| iShares Core S&P 500 ETF IVV | 0.03% | 894.38B | 1.09% | +19.68% | 1.49 |
| State Street SPDR S&P 500 ETF SPY | 0.09% | 789.23B | 1.00% | +19.71% | 1.49 |
| SPDR S&P 500 ETF Trust 1557.T | 0.09% | 789.09B | 0.49% | +37.54% | 2.26 |
| State Street SPDR S&P 500 ETF SPY.AX | 0.09% | 788.13B | 1.00% | +11.84% | 1.13 |
| Vanguard Total International Stock ETF VXUS | 0.05% | 652.30B | 2.61% | +20.58% | 1.21 |
| Invesco QQQ Trust, Series 1 QQQ | 0.18% | 481.14B | 0.43% | +28.14% | 1.43 |
| Vanguard Growth ETF VUG | 0.03% | 393.80B | 0.39% | +16.85% | 0.99 |
| Vanguard FTSE Developed Markets ETF VEA | 0.03% | 317.30B | 2.60% | +21.64% | 1.23 |
Cheaper alternatives
No fund of the class reaches 60% portfolio overlap — showing the cheapest funds of the class instead.
| Fund | TER | AUM (USD) | Overlap |
|---|---|---|---|
| Invesco QQQ Trust, Series 1 QQQ | 0.18% | 481.14B | 2.6% |
| Vanguard Small-Cap ETF VB | 0.03% | 182.70B | 1.8% |
| Vanguard Value ETF VTV | 0.03% | 245.00B | 1.7% |
| Vanguard Total Stock Market ETF VTI | 0.03% | 2.30T | 1.0% |
| State Street SPDR Portfolio S&P 500 ETF SPYM | 0.02% | 159.32B | 0.9% |

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