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Alnylam Pharmaceuticals, Inc. (ALNY)

USD288.06 -10.70 (-3.58%)
US NASDAQ NASDAQ 100 Healthcare Biotechnology
Address 675 West Kendall Street 2142
Cambridge, MA, US
CEO Yvonne L. Greenstreet
IPO 2004-06-01
CIK 1178670 ISIN US02043Q1076

Explore sections of this company profile

Also trades on Deutsche Börse · DUL.DE (EUR) London Stock Exchange · 0HD2.L (USD) NASDAQ Global Select · ALNY (USD)
Description

Alnylam Pharmaceuticals, Inc. is a biopharmaceutical company primarily dedicated to the discovery, development, and commercialization of innovative therapeutic solutions leveraging ribonucleic acid interference (RNAi) technology. Its robust pipeline of RNAi-based treatments addresses a range of critical therapeutic areas, including inherited genetic disorders, cardio-metabolic conditions, hepatic infectious diseases, and central nervous system (CNS) and ocular disorders. Currently, Alnylam offers several approved therapies: ONPATTRO (patisiran) for adults suffering from polyneuropathy associated with hereditary transthyretin-mediated amyloidosis; GIVLAARI for adult patients with acute hepatic porphyria (AHP); and OXLUMO (lumasiran) for primary hyperoxaluria type 1 (PH1). Beyond its commercial portfolio, the company maintains an active development pipeline. Key investigational therapies include givosiran, aimed at adolescent patients with AHP; patisiran, being explored for transthyretin amyloidosis (ATTR) with cardiomyopathy; cemdisiran for complement-mediated disorders; ALN-AAT02 for AAT deficiency-associated liver disease; ALN-HBV02 for chronic hepatitis B virus infection; Zilebesiran for hypertension; and ALN-HSD for non-alcoholic steatohepatitis (NASH). Additionally, other candidates such as Fitusiran for hemophilia and bleeding disorders, Inclisiran for hypercholesterolemia, an expanded indication for lumasiran for advanced PH1 and recurrent kidney stones, and vutrisiran for ATTR amyloidosis (currently in Phase 3 clinical trials) are also progressing. Alnylam also engages in strategic alliances with other pharmaceutical leaders. Notable collaborations include those with Regeneron Pharmaceuticals, Inc., focused on discovering and developing RNAi therapeutics for ocular and CNS targets, and with Sanofi Genzyme for broader RNAi therapeutic development and commercialization efforts. Further licensing and partnership agreements are in place with entities such as Novartis AG, Vir Biotechnology, Inc., Dicerna Pharmaceuticals, Inc., Ionis Pharmaceuticals, Inc., and PeptiDream, Inc. Established in 2002, Alnylam Pharmaceuticals maintains its corporate headquarters in Cambridge, Massachusetts.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Index membership

IndexAddedRemovedStatus
NASDAQ 100 2025-12-22 Active
Technical Outlook
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Indicator 1D1W2W3W1M
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Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
USD288.06 -10.70 (-3.58%)
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Volume Profile
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Liquidity & share structure
Average Volume
1M
Beta
0.27
Float Shares
132.51M
Free Float %
99.3%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
+2.52% -2.83% -9.34% -5.33% -35.50% -26.56% +8.08% +42.20% +118.98% +457.63% +4,759.07%
Rolling Volatility
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Relative Strength
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Monthly Returns Heatmap
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Daily Returns Distribution
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

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By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Analyst Consensus (52 ratings, all time) Buy
Price Targets & DCF
Current price
288.06
Low 351.00 +21.8%
Consensus 445.67 +54.7%
Median 445.50 +54.7%
High 530.00 +84.0%
Ratings Trend (MoM) 71% Bullish
Rating 2026-05 Change
Strong Buy 6 0
Buy 14 0
Hold 8 0
Sell 0 0
Strong Sell 0 0
Price Target Summary
Period # Analysts Avg Target
Last Month 2
408.50
+41.8%
Last Quarter 7
418.00
+45.1%
Last Year 30
460.47
+59.9%
All Time 69
344.72
+19.7%
Quality scores
Altman Z-Score
5.73
Safe zone
Piotroski F-Score
7 / 9
Strong
MOAT Score
3 / 10
No MOAT
Composite Rating
B
Overall Score
3 / 5
Medium
DCF Score
4 / 5
High
ROE Score
5 / 5
High
ROA Score
5 / 5
High
D/E Score
1 / 5
Low
P/E Score
1 / 5
Low
P/Book Score
1 / 5
Low
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
    +65.2% Q1'26: +96.4% (vs Q1'25)
  • EPS growth Biotechnology: +29.7%
    +206.9% Q1'26: +443.2% (vs Q1'25)
  • FCF margin FCF growth · Biotechnology: +16.2%
    -5.5% Q1'26: +4.2% (vs Q1'25)
  • EBIT margin Biotechnology: +0.0%
    +13.5% Q1'26: +13.1% (vs Q1'25)
  • ROIC Biotechnology: -16.1%
    Q1'26: -92.2% (vs Q1'25)
  • Share dilution Biotechnology: -3.4%
    +5.5% Q1'26: +6.6% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    2.29× Q1'26: 2.09× (vs Q1'25)
Valuation Multiples From To
Price Forecast (3Y) From To
Model
Adjust
P/E
Theoretical Return — If Invested Today

* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.

DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (0.30) × ERP
WACC = 97% × Ke + 3% × Kd (19.8%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Current price: 288.06
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2011
actual
Dec 2012
actual
Dec 2013
actual
Dec 2014
actual
Dec 2015
actual
Dec 2016
actual
Dec 2017
actual
Dec 2018
actual
Dec 2019
actual
Dec 2020
actual
Dec 2021
actual
Dec 2022
actual
Dec 2023
actual
Dec 2024
actual
Dec 2025
actual
Dec 2026
19 Rev. Ana.
15 EPS Ana.
Dec 2027
19 Rev. Ana.
14 EPS Ana.
Dec 2028
18 Rev. Ana.
16 EPS Ana.
Dec 2029
11 Rev. Ana.
14 EPS Ana.
Dec 2030
9 Rev. Ana.
14 EPS Ana.
Revenue
82.76M
est: 82.30M (+0.6%)
66.73M
est: 85.61M (-22.1%)
47.17M
est: 61.15M (-22.9%)
50.56M
est: 81.77M (-38.2%)
41.10M
est: 43.50M (-5.5%)
47.16M
est: 42.48M (+11.0%)
89.91M
est: 70.82M (+27.0%)
74.91M
est: 70.69M (+6.0%)
219.75M
est: 222.13M (-1.1%)
492.85M
est: 475.26M (+3.7%)
844.29M
est: 820.81M (+2.9%)
1.04B
est: 1.01B (+2.4%)
1.83B
est: 2.34B (-22.0%)
2.25B
est: 2.24B (+0.2%)
3.71B
est: 3.75B (-1.0%)
5.62B
5.50B – 6.07B
+49.7% YoY
7.38B
6.72B – 9.08B
+31.4% YoY
8.80B
8.80B – 8.80B
+19.3% YoY
10.16B
9.45B – 11.86B
+15.4% YoY
11.74B
10.93B – 13.71B
+15.6% YoY
EBITDA
-49.69M
est: -50.54M (+1.7%)
-51.71M
est: -139.33M (+62.9%)
-82.71M
est: -76.80M (-7.7%)
-172.29M
est: -478.85M (+64.0%)
-276.96M
est: -253.54M (-9.2%)
-409.46M
est: -387.83M (-5.6%)
-488.19M
est: -450.44M (-8.4%)
-754.24M
est: -729.10M (-3.4%)
-868.08M
est: -822.45M (-5.5%)
-736.33M
est: -659.42M (-11.7%)
-661.56M
est: -724.59M (+8.7%)
-926.56M
est: -775.24M (-19.5%)
-258.24M
est: -819.35M (+68.5%)
-178.85M
est: -783.79M (+77.2%)
557.24M
est: -1.31B (+142.5%)
-1.96B
-2.12B – -1.92B
-49.7% YoY
-2.58B
-3.17B – -2.35B
-31.4% YoY
-3.08B
-3.08B – -3.08B
-19.3% YoY
-3.55B
-4.14B – -3.30B
-15.4% YoY
-4.10B
-4.79B – -3.82B
-15.6% YoY
EBIT
-57.65M
est: -52.73M (-9.3%)
-63.57M
est: -169.98M (+62.6%)
-92.94M
est: -88.19M (-5.4%)
-184.21M
est: -498.22M (+63.0%)
-296.01M
est: -276.97M (-6.9%)
-424.59M
est: -416.30M (-2.0%)
-500.09M
est: -471.56M (-6.1%)
-760.67M
est: -789.56M (+3.7%)
-885.25M
est: -929.27M (+4.7%)
-771.10M
est: -772.07M (+0.1%)
-709.12M
est: -608.72M (-16.5%)
-971.03M
est: -565.12M (-71.8%)
-312.30M
est: -898.58M (+65.2%)
-235.52M
est: -859.57M (+72.6%)
501.58M
est: -1.44B (+134.9%)
-2.15B
-2.33B – -2.11B
-49.7% YoY
-2.83B
-3.48B – -2.57B
-31.4% YoY
-3.37B
-3.37B – -3.37B
-19.3% YoY
-3.89B
-4.55B – -3.62B
-15.4% YoY
-4.50B
-5.26B – -4.19B
-15.6% YoY
Net Income
-57.65M
est: -55.52M (-3.8%)
-106.01M
est: -132.74M (+20.1%)
-89.23M
est: -83.91M (-6.3%)
-360.40M
est: -439.32M (+18.0%)
-290.07M
est: -271.35M (-6.9%)
-410.11M
est: -402.69M (-1.8%)
-490.87M
est: -463.06M (-6.0%)
-761.50M
est: -735.72M (-3.5%)
-886.12M
est: -878.28M (-0.9%)
-858.28M
est: -777.85M (-10.3%)
-852.82M
est: -723.17M (-17.9%)
-1.13B
est: -770.44M (-46.8%)
-440.24M
est: -72.94M (-503.6%)
-278.16M
est: -319.09M (+12.8%)
313.75M
est: 308.23M (+1.8%)
1.03B
851.81M – 1.13B
+232.8% YoY
1.52B
1.16B – 1.62B
+47.9% YoY
1.98B
1.15B – 2.64B
+30.7% YoY
2.13B
1.94B – 2.59B
+7.3% YoY
2.62B
2.38B – 3.19B
+22.9% YoY
SGA
38.28M
est: 36.95M (+3.6%)
44.61M
est: 45.20M (-1.3%)
27.15M
est: 27.37M (-0.8%)
44.53M
est: 52.55M (-15.3%)
60.61M
est: 30.81M (+96.7%)
89.35M
est: 30.08M (+197.0%)
199.37M
est: 50.15M (+297.5%)
382.36M
est: 50.06M (+663.8%)
479.01M
est: 157.31M (+204.5%)
588.42M
est: 336.58M (+74.8%)
620.64M
est: 527.46M (+17.7%)
770.66M
est: 513.33M (+50.1%)
795.65M
est: 1.25B (-36.5%)
975.53M
est: 1.20B (-18.6%)
1.21B
est: 2.01B (-39.6%)
3.00B
2.94B – 3.25B
+49.7% YoY
3.95B
3.59B – 4.86B
+31.4% YoY
4.71B
4.70B – 4.71B
+19.3% YoY
5.43B
5.05B – 6.34B
+15.4% YoY
6.28B
5.84B – 7.33B
+15.6% YoY
EPS
-1.36
est: -1.31 (-3.8%)
-2.11
est: -3.00 (+29.7%)
-1.45
est: -1.48 (+1.7%)
-4.85
est: -2.72 (-78.6%)
-3.45
est: -3.34 (-3.4%)
-4.79
est: -4.88 (+1.8%)
-5.42
est: -5.29 (-2.5%)
-7.57
est: -7.65 (+1.0%)
-8.11
est: -7.90 (-2.7%)
-7.46
est: -7.20 (-3.6%)
-7.20
est: -6.44 (-11.7%)
-9.30
est: -8.95 (-3.9%)
-3.52
est: -0.58 (-507.7%)
-2.18
est: -2.06 (-5.8%)
2.39
est: 2.46 (-3.0%)
7.39
6.32 – 8.40
+200.0% YoY
10.65
8.59 – 12.05
+44.0% YoY
13.30
8.55 – 19.61
+25.0% YoY
15.81
14.38 – 19.25
+18.8% YoY
19.43
17.68 – 23.67
+22.9% YoY
Recent Grade Changes (3M)
Date Firm Previous New Grade Action
2026-05-05 HC Wainwright & Co. Buy Buy Maintain
2026-05-01 RBC Capital Outperform Outperform Maintain
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-11 B 3/5 4/5 5/5 5/5 1/5 1/5 1/5
2026-05-08 B 3/5 3/5 5/5 5/5 1/5 1/5 1/5
2026-05-07 B 3/5 3/5 5/5 5/5 1/5 1/5 1/5
2026-05-06 B 3/5 3/5 5/5 5/5 1/5 1/5 1/5
2026-05-05 B 3/5 3/5 5/5 5/5 1/5 1/5 1/5
2026-05-04 B 3/5 3/5 5/5 5/5 1/5 1/5 1/5
2026-05-01 B 3/5 3/5 5/5 5/5 1/5 1/5 1/5
2026-04-30 B 3/5 3/5 5/5 5/5 1/5 1/5 1/5
2026-04-29 B 3/5 3/5 5/5 5/5 1/5 1/5 1/5
2026-04-28 B 3/5 3/5 5/5 5/5 1/5 1/5 1/5
2026-04-27 B 3/5 3/5 5/5 5/5 1/5 1/5 1/5
2026-04-24 B 3/5 3/5 5/5 5/5 1/5 1/5 1/5
2026-04-23 B 3/5 3/5 5/5 5/5 1/5 1/5 1/5
2026-04-22 B 3/5 3/5 5/5 5/5 1/5 1/5 1/5
2026-04-21 B 3/5 3/5 5/5 5/5 1/5 1/5 1/5
2026-04-20 B 3/5 3/5 5/5 5/5 1/5 1/5 1/5
2026-04-17 B 3/5 4/5 5/5 5/5 1/5 1/5 1/5
2026-04-16 B 3/5 4/5 5/5 5/5 1/5 1/5 1/5
2026-04-15 B 3/5 3/5 5/5 5/5 1/5 1/5 1/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
1.57B
OE per share TTM
11.49
Owner's Yield
4.14%
Maintenance CapEx ratio
122.07%
Maint CapEx / Avg PPE
47.7%

Ownership Overview

Ownership breakdown
At a glance
Institutional holders
178
Total invested
643.65M
Insider transactions (90d)
0
Beneficial owners (>5%)
16
Beneficial owners (>5%)
# Reporting person Amount owned % of class Sole voting Shared voting Sole dispositive Shared dispositive Type Citizenship Filing date SEC filing
1 Abigail P. Johnson 16.72M 15.00% 16.72M IN Delaware 2020-02-07
2 FMR LLC 16.72M 15.00% 4.54M 16.72M HC Delaware 2020-02-07
3 The Vanguard Group - 23-1945930 10.70M 8.95% 114.6K 10.44M 260.9K IA Pennsylvania 2022-02-09
4 Baillie Gifford & Co (Scottish partnership) 10.62M 11.00% IA SCOTLAND UK 2022-01-18
5 Wellington Group Holdings LLP 10.06M 8.66% 9.75M HC Delaware 2021-02-03
6 Wellington Investment Advisors Holdings LLP 10.06M 8.66% 9.75M HC Delaware 2021-02-03
7 Wellington Management Company LLP 9.65M 8.31% 9.61M IA Delaware 2021-02-03
8 2 9.20M 10.70% 8.79M 9.20M IA California USA 2017-02-14
9 OF 4 PAGES 8.23M 8.30% 7.83M 8.23M IA California USA 2018-02-09
10 (1) BlackRock, Inc. 7.67M 6.40% 6.93M 7.67M HC Delaware 2022-02-03
11 Wellington Management Group LLP 6.84M 5.72% 6.58M 6.84M HC Massachusetts 2022-02-04
12 52-0556948 6.54M 5.40% 1.89M 6.54M IA Maryland 2022-02-14
13 PAGE 2 OF 4 PAGES 4.69M 4.60% 4.48M 4.69M IA California USA 2019-02-14
14 0 % 0.00% CO The Republic of France 2019-05-03
15 10. 0.00% CO Delaware 2017-08-09
16 VANGUARD SPECIALIZED FUNDS - VANGUARD HEALTH CARE FUND - 23-2439149 0.00% IV Delaware 2020-02-12

Institutional Activity (13F)

Institutional ownership trend From To
13F snapshot — 2026 Q1
Investors holding
178
-709 vs prev Q
New positions
26
Closed positions
696
Increased
93
Reduced
49
Put/Call ratio
0.00
Calls held
Puts held
37.9K
Top institutional holders
# Investor Shares / Δ Mkt value / Δ Own% / Δ Weight% / Δ Avg px / Perf. Hold / Status
1 MACQUARIE MANAGEMENT HOLDINGS, INC. 311.8K +311.8K (+100.0%) 123.97B +124.0B (+100.0%) 0.24% +0.238 pp 0.19% +0.187 pp USD397.65 +0.0% 1 qtrs NEW
2 CAPITAL WORLD INVESTORS 16.30M -132.5K (-0.8%) 6.48B -1.0B (-13.5%) 12.40% -0.272 pp 0.88% -0.142 pp USD196.17 +102.7% 50 qtrs
3 FMR LLC 15.90M -865.5K (-5.2%) 6.32B -1.3B (-17.3%) 12.03% -0.905 pp 0.32% -0.075 pp USD168.20 +136.4% 70 qtrs
4 VANGUARD GROUP INC 13.55M -11.5K (-0.1%) 5.39B -796.1M (-12.9%) 10.35% -0.115 pp 0.08% -0.015 pp USD113.95 +249.0% 84 qtrs
5 BLACKROCK, INC. 10.40M +497.3K (+5.0%) 4.14B -380.1M (-8.4%) 7.94% +0.302 pp 0.07% -0.009 pp USD282.29 +40.9% 6 qtrs
6 CAPITAL RESEARCH GLOBAL INVESTORS 6.78M -443.1K (-6.1%) 2.70B -597.6M (-18.1%) 5.16% -0.412 pp 0.50% -0.120 pp USD234.64 +69.5% 13 qtrs
7 JPMORGAN CHASE & CO 4.72M +176.2K (+3.9%) 1.88B -195.1M (-9.4%) 3.59% +0.087 pp 0.12% -0.006 pp USD336.55 +18.2% 51 qtrs
8 STATE STREET CORP 3.23M +147.5K (+4.8%) 1.28B -121.2M (-8.6%) 2.46% +0.089 pp 0.04% -0.006 pp USD124.90 +218.4% 51 qtrs
9 GEODE CAPITAL MANAGEMENT, LLC 2.65M +151.5K (+6.1%) 1.06B -79.5M (-7.0%) 2.02% +0.096 pp 0.07% -0.007 pp USD167.43 +137.5% 78 qtrs
10 BAILLIE GIFFORD & CO 2.60M -188.4K (-6.8%) 1.03B -237.7M (-18.7%) 1.98% -0.172 pp 0.86% -0.083 pp USD97.48 +307.9% 51 qtrs
11 NORGES BANK 2.25M +2.3M (+100.0%) 895.82M +895.8M (+100.0%) 1.71% +1.714 pp 0.10% +0.096 pp USD397.65 +0.0% 1 qtrs NEW
12 INVESCO LTD. 2.17M +684.0K (+46.2%) 861.25M +185.5M (+27.5%) 1.65% +0.511 pp 0.13% +0.026 pp USD326.06 +22.0% 57 qtrs
13 DODGE & COX 1.96M -356.8K (-15.4%) 781.15M -277.3M (-26.2%) 1.49% -0.304 pp 0.42% -0.150 pp USD82.64 +381.2% 39 qtrs
14 T. ROWE PRICE INVESTMENT MANAGEMENT, INC. 1.75M -420.3K (-19.3%) 697.34M -294.0M (-29.7%) 1.33% -0.350 pp 0.44% -0.166 pp USD212.25 +87.3% 14 qtrs
15 PRICE T ROWE ASSOCIATES INC /MD/ 1.70M -97.5K (-5.4%) 677.13M -143.8M (-17.5%) 1.30% -0.089 pp 0.07% -0.015 pp USD131.17 +203.2% 75 qtrs
16 WELLINGTON MANAGEMENT GROUP LLP 1.63M -197.4K (-10.8%) 647.74M -185.1M (-22.2%) 1.23% -0.177 pp 0.11% -0.032 pp USD106.32 +274.0% 50 qtrs
17 ORBIS ALLAN GRAY LTD 1.62M -332.7K (-17.1%) 643.48M -246.2M (-27.7%) 1.22% -0.281 pp 2.70% -1.122 pp USD271.75 +46.3% 7 qtrs
18 AMERICAN CENTURY COMPANIES INC 1.49M -156.3K (-9.5%) 590.58M -157.9M (-21.1%) 1.12% -0.143 pp 0.30% -0.084 pp USD181.73 +118.8% 31 qtrs
19 TWO SIGMA ADVISERS, LP 1.13M +240.1K (+26.9%) 450.36M +43.4M (+10.7%) 0.86% +0.176 pp 0.88% +0.061 pp USD393.72 +1.0% 17 qtrs
20 ARROWSTREET CAPITAL, LIMITED PARTNERSHIP 1.13M -228.4K (-16.9%) 448.22M -169.9M (-27.5%) 0.85% -0.193 pp 0.26% -0.127 pp USD439.57 -9.5% 4 qtrs
21 MORGAN STANLEY 970.2K +244.1K (+33.6%) 385.78M +54.7M (+16.5%) 0.74% +0.181 pp 0.02% +0.003 pp USD248.87 +59.8% 51 qtrs
22 LEGAL & GENERAL GROUP PLC 961.5K +73.7K (+8.3%) 382.34M -22.5M (-5.6%) 0.73% +0.047 pp 0.08% -0.006 pp USD169.28 +134.9% 44 qtrs
23 AQR CAPITAL MANAGEMENT LLC 920.0K +176.0K (+23.6%) 365.82M +29.8M (+8.9%) 0.70% +0.122 pp 0.19% -0.024 pp USD399.64 -0.5% 17 qtrs
24 NORTHERN TRUST CORP 857.7K +24.6K (+3.0%) 341.08M -38.8M (-10.2%) 0.65% +0.006 pp 0.04% -0.005 pp USD138.98 +186.1% 51 qtrs
25 UBS GROUP AG 825.8K +337.6K (+69.2%) 328.40M +105.8M (+47.5%) 0.63% +0.254 pp 0.05% +0.018 pp USD320.45 +24.1% 45 qtrs
26 FRANKLIN RESOURCES INC 787.6K +73.6K (+10.3%) 313.20M -12.4M (-3.8%) 0.60% +0.049 pp 0.08% -0.004 pp USD286.65 +38.7% 28 qtrs
27 QUBE RESEARCH & TECHNOLOGIES LTD 774.7K -36.6K (-4.5%) 308.05M -61.9M (-16.7%) 0.59% -0.040 pp 0.31% -0.069 pp USD456.00 -12.8% 10 qtrs
28 DEUTSCHE BANK AG\ 712.0K +105.7K (+17.4%) 283.12M +6.6M (+2.4%) 0.54% +0.074 pp 0.09% 0.000 pp USD225.64 +76.2% 50 qtrs
29 BANK OF AMERICA CORP /DE/ 685.2K -813.3K (-54.3%) 272.46M -410.9M (-60.1%) 0.52% -0.633 pp 0.02% -0.027 pp USD283.57 +40.2% 52 qtrs
30 UBS ASSET MANAGEMENT AMERICAS INC 652.4K -56.2K (-7.9%) 259.41M -63.7M (-19.7%) 0.50% -0.050 pp 0.05% -0.015 pp USD160.16 +148.3% 56 qtrs
31 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 647.8K +29.1K (+4.7%) 257.61M -24.5M (-8.7%) 0.49% +0.016 pp 0.04% -0.005 pp USD178.03 +123.4% 72 qtrs
32 FEDERATED HERMES, INC. 628.1K +78.0K (+14.2%) 249.75M -1.1M (-0.4%) 0.48% +0.054 pp 0.42% -0.026 pp USD342.32 +16.2% 13 qtrs
33 TWO SIGMA INVESTMENTS, LP 616.1K +20.2K (+3.4%) 245.00M -26.7M (-9.8%) 0.47% +0.011 pp 0.35% -0.059 pp USD355.16 +12.0% 16 qtrs
34 AMUNDI 608.9K +224.6K (+58.5%) 242.12M +68.4M (+39.4%) 0.46% +0.168 pp 0.07% +0.010 pp USD257.49 +54.4% 19 qtrs
35 CLEARBRIDGE INVESTMENTS, LLC 597.0K -25.4K (-4.1%) 237.40M -46.4M (-16.4%) 0.45% -0.026 pp 0.19% -0.024 pp USD339.03 +17.3% 4 qtrs
36 ROYAL BANK OF CANADA 591.5K +154.7K (+35.4%) 235.21M +36.0M (+18.1%) 0.45% +0.115 pp 0.04% +0.006 pp USD273.47 +45.4% 51 qtrs
37 NUVEEN, LLC 565.8K -22.0K (-3.7%) 224.99M -43.1M (-16.1%) 0.43% -0.021 pp 0.06% -0.012 pp USD270.02 +47.3% 4 qtrs
38 MARSHALL WACE, LLP 549.9K +41.6K (+8.2%) 218.68M -13.1M (-5.7%) 0.42% +0.028 pp 0.20% -0.036 pp USD358.74 +10.8% 6 qtrs
39 SUSQUEHANNA INTERNATIONAL GROUP, LLP 523.9K -277.3K (-34.6%) 208.33M -157.0M (-43.0%) 0.40% -0.218 pp 0.02% -0.018 pp USD390.41 +1.9% 51 qtrs
40 BANK OF NEW YORK MELLON CORP 504.1K +84.4K (+20.1%) 200.47M +9.0M (+4.7%) 0.38% +0.060 pp 0.04% -0.002 pp USD177.80 +123.7% 66 qtrs
41 198.8K +198.8K (+100.0%) 198.83M +198.8M (+100.0%) 0.15% +0.152 pp 0.12% +0.115 pp USD397.65 +0.0% 1 qtrs NEW
42 MASSACHUSETTS FINANCIAL SERVICES CO /MA/ 495.3K +138.8K (+38.9%) 196.96M +34.4M (+21.1%) 0.38% +0.102 pp 0.06% +0.013 pp USD439.65 -9.6% 2 qtrs
43 LOOMIS SAYLES & CO L P 488.9K -11.8K (-2.4%) 194.41M -33.9M (-14.8%) 0.37% -0.014 pp 0.23% -0.037 pp USD177.57 +123.9% 19 qtrs
44 BELLEVUE GROUP AG 445.9K -621.0 (-0.1%) 177.31M -26.3M (-12.9%) 0.34% -0.004 pp 3.36% -0.871 pp USD81.93 +385.4% 40 qtrs
45 D. E. SHAW & CO., INC. 444.5K +245.1K (+122.9%) 176.75M +85.8M (+94.4%) 0.34% +0.182 pp 0.10% +0.046 pp USD368.00 +8.1% 56 qtrs
46 1832 ASSET MANAGEMENT L.P. 440.1K -19.2K (-4.2%) 175.02M -34.4M (-16.4%) 0.33% -0.021 pp 0.13% -0.032 pp USD375.25 +6.0% 4 qtrs
47 JACOBS LEVY EQUITY MANAGEMENT, INC 401.4K -9.0K (-2.2%) 159.61M -27.5M (-14.7%) 0.30% -0.013 pp 0.62% -0.127 pp USD447.99 -11.2% 4 qtrs
48 BNP PARIBAS ARBITRAGE, SNC 389.4K +236.4K (+154.5%) 154.86M +85.1M (+121.9%) 0.30% +0.179 pp 0.07% +0.033 pp USD363.44 +9.4% 51 qtrs
49 RAYMOND JAMES FINANCIAL INC 388.7K +11.4K (+3.0%) 154.43M -17.6M (-10.2%) 0.29% +0.003 pp 0.05% -0.007 pp USD301.08 +32.1% 5 qtrs
50 GOLDMAN SACHS GROUP INC 375.3K -163.0K (-30.3%) 149.25M -96.2M (-39.2%) 0.29% -0.130 pp 0.02% -0.012 pp USD233.54 +70.3% 73 qtrs
51 WELLS FARGO & COMPANY/MN 370.0K +350.0K (+1,750.0%) 147.13M +138.0M (+1,513.3%) 0.28% +0.267 pp 0.03% +0.025 pp USD388.87 +2.3% 5 qtrs
52 SWISS NATIONAL BANK 359.2K -16.6K (-4.4%) 142.84M -28.5M (-16.6%) 0.27% -0.017 pp 0.09% -0.014 pp USD131.73 +201.9% 51 qtrs
53 SQUAREPOINT OPS LLC 351.0K +205.4K (+141.1%) 139.56M +73.2M (+110.3%) 0.27% +0.155 pp 0.15% +0.082 pp USD420.17 -5.4% 16 qtrs
54 KBC GROUP NV 348.2K +74.8K (+27.4%) 138.46M +13.8M (+11.1%) 0.26% +0.054 pp 0.32% +0.017 pp USD365.44 +8.8% 43 qtrs
55 WORLDQUANT MILLENNIUM ADVISORS LLC 343.4K +122.8K (+55.7%) 136.57M +36.0M (+35.7%) 0.26% +0.092 pp 0.53% +0.095 pp USD360.57 +10.3% 14 qtrs
56 SUMITOMO MITSUI TRUST HOLDINGS, INC. 327.8K +13.3K (+4.2%) 130.33M -13.1M (-9.1%) 0.25% +0.007 pp 0.08% -0.006 pp USD152.25 +161.2% 33 qtrs
57 GILDER GAGNON HOWE & CO LLC 319.3K -10.0K (-3.0%) 126.97M -23.2M (-15.4%) 0.24% -0.010 pp 1.34% -0.190 pp USD52.19 +661.9% 51 qtrs
58 PICTET ASSET MANAGEMENT HOLDING SA 316.1K -71.5K (-18.4%) 125.78M -50.2M (-28.5%) 0.24% -0.058 pp 0.12% -0.048 pp USD186.41 +113.3% 10 qtrs
59 JANE STREET GROUP, LLC 311.3K -647.5K (-67.5%) 123.78M -313.4M (-71.7%) 0.24% -0.503 pp 0.02% -0.048 pp USD449.45 -11.5% 37 qtrs
60 DIMENSIONAL FUND ADVISORS LP 301.9K +59.9K (+24.8%) 120.03M +9.7M (+8.8%) 0.23% +0.043 pp 0.03% +0.002 pp USD196.43 +102.4% 51 qtrs
61 ORBIMED ADVISORS LLC 288.8K -12.8K (-4.2%) 114.84M -22.7M (-16.5%) 0.22% -0.012 pp 2.35% -0.888 pp USD240.13 +65.6% 9 qtrs
62 ALLSPRING GLOBAL INVESTMENTS HOLDINGS, LLC 278.7K -32.1K (-10.3%) 111.51M -31.7M (-22.1%) 0.21% -0.027 pp 0.18% -0.049 pp USD277.44 +43.3% 17 qtrs
63 JENNISON ASSOCIATES LLC 277.8K -27.1K (-8.9%) 110.45M -28.6M (-20.5%) 0.21% -0.024 pp 0.07% -0.015 pp USD250.79 +58.6% 5 qtrs
64 LOS ANGELES CAPITAL MANAGEMENT LLC 240.1K +80.7K (+50.6%) 107.92M +35.2M (+48.5%) 0.18% +0.060 pp 0.37% +0.121 pp USD385.38 +3.2% 14 qtrs
65 CONGRESS ASSET MANAGEMENT CO /MA 269.2K +150.4K (+126.6%) 107.06M +52.9M (+97.6%) 0.21% +0.114 pp 0.75% +0.393 pp USD423.40 -6.1% 2 qtrs
66 TD ASSET MANAGEMENT INC 269.1K -43.4K (-13.9%) 107.01M -35.5M (-24.9%) 0.20% -0.036 pp 0.09% -0.030 pp USD156.33 +154.4% 51 qtrs
67 CANADA PENSION PLAN INVESTMENT BOARD 258.7K +122.4K (+89.8%) 102.88M +40.7M (+65.5%) 0.20% +0.092 pp 0.07% +0.025 pp USD394.37 +0.8% 44 qtrs
68 FIRST TRUST ADVISORS LP 257.0K +46.6K (+22.1%) 102.18M +6.2M (+6.5%) 0.19% +0.032 pp 0.07% +0.003 pp USD253.04 +57.1% 45 qtrs
69 ROYAL LONDON ASSET MANAGEMENT LTD 253.1K -4.2K (-1.6%) 100.63M -16.7M (-14.2%) 0.19% -0.006 pp 0.21% -0.041 pp USD176.17 +125.7% 31 qtrs
70 POLAR CAPITAL HOLDINGS PLC 240.6K -10.9K (-4.3%) 95.68M -19.0M (-16.6%) 0.18% -0.010 pp 0.37% -0.182 pp USD223.92 +77.6% 21 qtrs
71 CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM 237.0K +7.4K (+3.2%) 94.25M -10.5M (-10.0%) 0.18% +0.003 pp 0.05% -0.009 pp USD169.26 +134.9% 58 qtrs
72 CANDRIAM S.C.A. 224.3K +11.9K (+5.6%) 89.21M -7.7M (-7.9%) 0.17% +0.006 pp 0.44% -0.063 pp USD165.71 +140.0% 45 qtrs
73 BARCLAYS PLC 222.6K +117.4K (+111.6%) 88.50M +59.6M (+205.9%) 0.17% +0.089 pp 0.02% +0.014 pp USD300.78 +32.2% 51 qtrs
74 VICTORY CAPITAL MANAGEMENT INC 220.9K +40.5K (+22.5%) 87.83M +5.6M (+6.8%) 0.17% +0.028 pp 0.05% +0.002 pp USD324.55 +22.5% 26 qtrs
75 FENGHE FUND MANAGEMENT PTE. LTD. 218.7K +218.7K (+100.0%) 86.97M +87.0M (+100.0%) 0.17% +0.166 pp 4.90% +4.896 pp USD397.65 +0.0% 1 qtrs NEW
76 PROSHARE ADVISORS LLC 211.1K +206.4K (+4,457.9%) 83.93M +81.8M (+3,874.7%) 0.16% +0.157 pp 0.15% +0.144 pp USD392.35 +1.4% 54 qtrs
77 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 201.8K -2.0K (-1.0%) 80.25M -12.7M (-13.6%) 0.15% -0.005 pp 0.08% -0.015 pp USD95.49 +316.4% 52 qtrs
78 CIBC PRIVATE WEALTH GROUP, LLC 200.4K -13.8K (-6.4%) 79.70M -18.0M (-18.4%) 0.15% -0.013 pp 0.13% -0.033 pp USD183.01 +117.3% 20 qtrs
79 HUDSON BAY CAPITAL MANAGEMENT LP 200.0K +200.0K (+100.0%) 79.53M +79.5M (+100.0%) 0.15% +0.153 pp 0.26% +0.262 pp USD397.65 +0.0% 1 qtrs NEW
80 VOYA INVESTMENT MANAGEMENT LLC 198.6K -174.7K (-46.8%) 78.98M -91.3M (-53.6%) 0.15% -0.137 pp 0.08% -0.092 pp USD355.34 +11.9% 51 qtrs
81 RHUMBLINE ADVISERS 195.3K -1.2K (-0.6%) 77.65M -12.0M (-13.3%) 0.15% -0.003 pp 0.06% -0.009 pp USD149.61 +165.8% 51 qtrs
82 KOREA INVESTMENT CORP 189.8K -7.1K (-3.6%) 75.46M -14.3M (-16.0%) 0.14% -0.008 pp 0.15% -0.036 pp USD325.25 +22.3% 24 qtrs
83 AMERIPRISE FINANCIAL INC 181.1K -44.7K (-19.8%) 72.03M -31.0M (-30.1%) 0.14% -0.037 pp 0.02% -0.007 pp USD284.62 +39.7% 34 qtrs
84 CITIGROUP INC 172.6K +111.7K (+183.5%) 68.62M +40.9M (+147.2%) 0.13% +0.084 pp 0.03% +0.018 pp USD350.06 +13.6% 61 qtrs
85 NATIONAL PENSION SERVICE 168.1K -9.1K (-5.1%) 66.86M -14.0M (-17.3%) 0.13% -0.009 pp 0.05% -0.013 pp USD170.09 +133.8% 23 qtrs
86 RUSSELL INVESTMENTS GROUP, LTD. 165.7K -30.2K (-15.4%) 65.90M -23.3M (-26.1%) 0.13% -0.026 pp 0.07% -0.030 pp USD344.23 +15.5% 37 qtrs
87 VOLORIDGE INVESTMENT MANAGEMENT, LLC 160.6K -196.2K (-55.0%) 63.85M -98.9M (-60.8%) 0.12% -0.153 pp 0.22% -0.322 pp USD452.00 -12.0% 7 qtrs
88 SCS CAPITAL MANAGEMENT LLC 149.6K -1.1K (-0.7%) 59.49M -9.2M (-13.4%) 0.11% -0.002 pp 0.63% -0.118 pp USD270.02 +47.3% 4 qtrs
89 ROBECO INSTITUTIONAL ASSET MANAGEMENT B.V. 144.7K +31.6K (+28.0%) 57.55M +6.0M (+11.6%) 0.11% +0.023 pp 0.08% +0.007 pp USD295.78 +34.4% 24 qtrs
90 MAN GROUP PLC 144.2K +72.5K (+101.2%) 57.35M +24.7M (+75.5%) 0.11% +0.054 pp 0.10% +0.041 pp USD411.30 -3.3% 18 qtrs
91 683 CAPITAL MANAGEMENT, LLC 141.1K +5.4K (+4.0%) 56.11M -5.8M (-9.3%) 0.11% +0.003 pp 2.44% -0.792 pp USD290.92 +36.7% 10 qtrs
92 MITSUBISHI UFJ KOKUSAI ASSET MANAGEMENT CO., LTD. 138.8K +18.0K (+14.9%) 55.54M +462.7K (+0.8%) 0.11% +0.012 pp 0.04% -0.002 pp USD240.09 +65.6% 43 qtrs
93 JANUS HENDERSON GROUP PLC 136.4K +570.0 (+0.4%) 54.25M -7.7M (-12.4%) 0.10% -0.002 pp 0.02% -0.004 pp USD194.95 +104.0% 43 qtrs
94 HANDELSBANKEN FONDER AB 136.2K -19.2K (-12.3%) 54.15M -16.7M (-23.6%) 0.10% -0.016 pp 0.16% -0.061 pp USD256.33 +55.1% 23 qtrs
95 ABRDN PLC 132.8K -24.6K (-15.6%) 52.83M -18.9M (-26.3%) 0.10% -0.020 pp 0.08% -0.032 pp USD199.37 +99.5% 31 qtrs
96 UNIVERSAL- BETEILIGUNGS- UND SERVICEGESELLSCHAFT MBH 124.6K +14.1K (+12.7%) 49.40M -1.0M (-2.0%) 0.09% +0.010 pp 0.08% -0.004 pp USD253.66 +56.8% 5 qtrs
Ownership breakdown by holder

Insider Activity

Insider Activity — Latest Quarter
Ratio by transactions
0.13
Bearish
Ratio by volume
3.00
Bullish
Buys
29
Sells
232
Shares acquired
300.3K
Shares disposed
83.7K
Cash buys
Cash sales
228.00
Net activity
+216,611
Insider buys vs sells (history) From To
Recent insider transactions From To
Date Person Role Transaction A/D Security Shares Price Value Owned after D/I Filing
2026-04-06 McLaughlin Melissa Officer S-Sale D Common Stock 56 320.14 17.9K 11,673 D
2026-04-02 McLaughlin Melissa Officer S-Sale D Common Stock 265 316.61 83.9K 13,088 D
2026-03-25 McLaughlin Melissa Officer Common Stock 0 0.00 13,353 D
2026-03-05 Garg Pushkal Officer S-Sale D Common Stock 654 322.33 210.8K 20,443 D
2026-03-05 Fitzgerald Kevin Joseph Officer S-Sale D Common Stock 153 326.24 49.9K 20,569 D
2026-03-04 Tanguler Tolga Officer S-Sale D Common Stock 208 325.67 67.7K 34,297 D
2026-03-04 Poulton Jeffrey V. Officer S-Sale D Common Stock 223 325.67 72.6K 61,805 D
2026-03-04 Greenstreet Yvonne Director / Officer S-Sale D Common Stock 129 320.01 41.3K 98,364 D
2026-03-04 Garg Pushkal Officer S-Sale D Common Stock 106 319.03 33.8K 23,300 D
2026-03-04 Fitzgerald Kevin Joseph Officer S-Sale D Common Stock 57 325.67 18.6K 21,227 D
2026-03-03 Garg Pushkal Officer S-Sale D Common Stock 640 320.48 205.1K 23,869 D
2026-03-03 Fitzgerald Kevin Joseph Officer S-Sale D Common Stock 359 321.58 115.4K 21,860 D
2026-03-02 Tanguler Tolga Officer S-Sale D Common Stock 100 328.71 32.9K 36,988 D
2026-03-02 SUPRAN BRYAN Officer A-Award A Stock Option (right to buy) 3,381 325.07 1.10M 3,381 D
2026-03-02 Poulton Jeffrey V. Officer S-Sale D Common Stock 234 329.71 77.2K 64,567 D
2026-03-02 Greenstreet Yvonne Director / Officer S-Sale D Common Stock 1,669 326.81 545.4K 102,078 D
2026-03-02 Garg Pushkal Officer S-Sale D Common Stock 50 323.62 16.2K 26,848 D
2026-03-02 Fitzgerald Kevin Joseph Officer S-Sale D Common Stock 94 331.93 31.2K 23,549 D
2026-02-27 Tanguler Tolga Officer M-Exempt D Restricted Stock Units 1,666 0.00 0 D
2026-02-27 Poulton Jeffrey V. Officer M-Exempt A Common Stock 1,908 0.00 61,710 D
2026-02-27 Greenstreet Yvonne Director / Officer M-Exempt D Restricted Stock Units 5,921 0.00 0 D
2026-02-27 Garg Pushkal Officer M-Exempt A Common Stock 1,908 0.00 26,756 D
2026-02-23 Fitzgerald Kevin Joseph Officer A-Award A Common Stock 158 0.00 21,422 D
2026-02-17 Fitzgerald Kevin Joseph Officer S-Sale D Common Stock 2,041 331.96 677.5K 21,264 D
2026-02-13 Tanguler Tolga Officer S-Sale D Common Stock 1,959 310.08 607.4K 31,769 D
2026-02-13 Poulton Jeffrey V. Officer S-Sale D Common Stock 2,242 310.08 695.2K 59,802 D
2026-02-13 Greenstreet Yvonne Director / Officer S-Sale D Common Stock 6,958 310.08 2.16M 85,662 D
2026-02-13 Garg Pushkal Officer S-Sale D Common Stock 2,242 310.08 695.2K 24,848 D
2026-02-13 Fitzgerald Kevin Joseph Officer S-Sale D Common Stock 1,959 310.08 607.4K 23,305 D
2026-02-12 Tanguler Tolga Officer A-Award A Common Stock 4,000 0.00 33,728 D
2026-02-12 Poulton Jeffrey V. Officer A-Award A Common Stock 4,579 0.00 62,044 D
2026-02-12 Greenstreet Yvonne Director / Officer A-Award A Common Stock 14,209 0.00 92,620 D
2026-02-12 Garg Pushkal Officer A-Award A Common Stock 4,579 0.00 27,090 D
2026-02-12 Fitzgerald Kevin Joseph Officer A-Award A Common Stock 4,000 0.00 25,264 D
2026-01-13 Fitzgerald Kevin Joseph Officer S-Sale D Common Stock 122 374.33 45.7K 21,264 D
2026-01-12 Tanguler Tolga Officer S-Sale D Common Stock 220 365.56 80.4K 30,020 D
2026-01-12 Poulton Jeffrey V. Officer S-Sale D Common Stock 27 377.82 10.2K 57,465 D
2026-01-12 Greenstreet Yvonne Director / Officer S-Sale D Common Stock 537 359.14 192.9K 85,287 D
2026-01-12 Garg Pushkal Officer S-Sale D Common Stock 15 377.82 5.7K 22,511 D
2026-01-12 Fitzgerald Kevin Joseph Officer S-Sale D Common Stock 39 353.95 13.8K 25,025 D
2026-01-11 Tanguler Tolga Officer A-Award A Common Stock 3,800 0.00 31,238 D
2026-01-11 Poulton Jeffrey V. Officer A-Award A Common Stock 6,193 0.00 60,245 D
2026-01-11 Greenstreet Yvonne Director / Officer A-Award A Common Stock 19,003 0.00 87,988 D
2026-01-11 Garg Pushkal Officer A-Award A Common Stock 3,800 0.00 24,021 D
2026-01-11 Fitzgerald Kevin Joseph Officer A-Award A Common Stock 3,800 0.00 25,064 D
2026-01-05 Arbuckle Stuart A Director A-Award A Stock Option (right to buy) 3,279 397.83 1.30M 3,279 D
2025-11-26 Greenstreet Yvonne Director / Officer M-Exempt D Stock Option (right to buy) 839 119.13 100.0K 0 D
2025-11-17 Fitzgerald Kevin Joseph Officer S-Sale D Common Stock 262 457.39 119.8K 24,005 D
2025-11-13 Greenstreet Yvonne Director / Officer S-Sale D Common Stock 1,599 452.85 724.1K 66,746 D
2025-11-12 Greenstreet Yvonne Director / Officer S-Sale D Common Stock 430 458.42 197.1K 65,409 D
2025-10-03 Garg Pushkal Officer S-Sale D Common Stock 215 454.37 97.7K 20,221 D
2025-10-02 Tanguler Tolga Officer S-Sale D Common Stock 157 453.77 71.2K 27,661 D
2025-10-02 Poulton Jeffrey V. Officer S-Sale D Common Stock 150 446.53 67.0K 57,723 D
2025-10-02 Greenstreet Yvonne Director / Officer S-Sale D Common Stock 548 448.77 245.9K 73,264 D
2025-10-02 Garg Pushkal Officer S-Sale D Common Stock 249 449.79 112.0K 25,580 D
2025-10-02 Fitzgerald Kevin Joseph Officer S-Sale D Common Stock 150 448.77 67.3K 27,379 D
2025-10-01 Tanguler Tolga Officer A-Award A Common Stock 2,851 0.00 28,843 D
2025-10-01 SUPRAN BRYAN Officer A-Award A Common Stock 13,026 0.00 13,026 D
2025-10-01 Poulton Jeffrey V. Officer A-Award A Common Stock 4,644 0.00 57,873 D
2025-10-01 Greenstreet Yvonne Director / Officer A-Award A Common Stock 3,860 0.00 60,081 D
2025-10-01 Garg Pushkal Officer A-Award A Common Stock 3,108 0.00 23,329 D
2025-10-01 Fitzgerald Kevin Joseph Officer A-Award A Common Stock 2,102 0.00 24,821 D
2025-09-15 SUPRAN BRYAN Officer 0 0.00 0
2025-09-09 Reitan Colleen F Director S-Sale D Common Stock 222 471.25 104.6K 8,403 D
2025-08-29 Tanguler Tolga Officer S-Sale D Common Stock 266 451.52 120.1K 26,136 D
2025-08-19 Garg Pushkal Officer S-Sale D Common Stock 276 455.41 125.7K 21,400 D
2025-08-18 Tanguler Tolga Officer S-Sale D Common Stock 90 449.92 40.5K 30,733 D
2025-08-18 Poulton Jeffrey V. Officer S-Sale D Common Stock 886 454.04 402.3K 50,532 D
2025-08-18 Greenstreet Yvonne Director / Officer S-Sale D Common Stock 60 455.82 27.3K 56,221 D
2025-08-18 Garg Pushkal Officer S-Sale D Common Stock 39 447.98 17.5K 23,033 D
2025-08-18 Fitzgerald Kevin Joseph Officer S-Sale D Common Stock 543 454.04 246.5K 22,972 D
2025-08-18 BONNEY MICHAEL W Director M-Exempt D Stock Option (right to buy) 11,250 70.20 789.8K 0 D
2025-08-15 Tanguler Tolga Officer A-Award A Common Stock 2,851 0.00 30,862 D
2025-08-15 Poulton Jeffrey V. Officer A-Award A Common Stock 4,644 0.00 52,395 D
2025-08-15 Greenstreet Yvonne Director / Officer A-Award A Common Stock 14,252 0.00 63,200 D
2025-08-15 Garg Pushkal Officer A-Award A Common Stock 2,851 0.00 23,072 D
2025-08-15 Fitzgerald Kevin Joseph Officer A-Award A Common Stock 2,851 0.00 24,115 D
2025-08-14 Ausiello Dennis A Director M-Exempt A Common Stock 9,000 72.01 648.1K 9,911 D
2025-07-01 Fitzgerald Kevin Joseph Officer A-Award A Common Stock 7,763 0.00 21,264 D
2025-06-02 Greenstreet Yvonne Director / Officer S-Sale D Common Stock 19,297 306.00 5.90M 48,948 D
2025-05-30 Greenstreet Yvonne Director / Officer S-Sale D Common Stock 25,469 304.00 7.74M 55,119 D
2025-05-16 Greenstreet Yvonne Director / Officer G-Gift D Common Stock 8,376 0.00 48,948 D
2025-05-15 BONNEY MICHAEL W Director S-Sale D Common Stock 1,263 277.16 350.1K 22,994 D
2025-05-08 Sigal Charles Elliott Director A-Award A Stock Option (right to buy) 1,558 258.35 402.5K 1,558 D
2025-05-08 SCHULMAN AMY W Director A-Award A Stock Option (right to buy) 1,558 258.35 402.5K 1,558 D
2025-05-08 Reitan Colleen F Director A-Award A Stock Option (right to buy) 1,558 258.35 402.5K 1,558 D
2025-05-08 PYOTT DAVID E I Director A-Award A Stock Option (right to buy) 1,558 258.35 402.5K 1,558 D
2025-05-08 KELLOGG PETER N Director A-Award A Common Stock 775 0.00 775 D
2025-05-08 HAMBURG MARGARET A Director A-Award A Stock Option (right to buy) 1,558 258.35 402.5K 1,558 D
2025-05-08 Bertozzi Carolyn R Director A-Award A Common Stock 775 0.00 775 D
2025-05-08 BRANDICOURT OLIVIER Director A-Award A Common Stock 775 0.00 775 D
2025-05-08 BONNEY MICHAEL W Director A-Award A Stock Option (right to buy) 1,558 258.35 402.5K 1,558 D
2025-05-08 Ausiello Dennis A Director A-Award A Stock Option (right to buy) 1,558 258.35 402.5K 1,558 D
2025-05-02 Greenstreet Yvonne Director / Officer G-Gift D Common Stock 41,311 0.00 57,324 D
2025-04-16 Reitan Colleen F Director S-Sale D Common Stock 36 232.86 8.4K 0 D
2025-03-24 PYOTT DAVID E I Director S-Sale D Common Stock 7,440 299.00 2.22M 136 D
2025-03-24 Garg Pushkal Officer M-Exempt A Common Stock 5,445 42.22 229.9K 25,666 D
2025-03-21 Garg Pushkal Officer S-Sale D Common Stock 4,321 285.00 1.23M 20,221 D
2025-03-13 SCHULMAN AMY W Director M-Exempt D Stock Option (right to buy) 2,750 131.21 360.8K 0 D
2025-03-04 Garg Pushkal Officer S-Sale D Common Stock 147 239.25 35.2K 25,203 D
2025-03-04 Fitzgerald Kevin Joseph Officer S-Sale D Common Stock 121 239.24 28.9K 14,224 D
2025-03-03 Tanguler Tolga Officer S-Sale D Common Stock 29 246.18 7.1K 28,014 D
2025-03-03 Poulton Jeffrey V. Officer A-Award A Common Stock 15,117 0.00 49,015 D
2025-03-03 Hesslein Robert W. Officer A-Award A Stock Option (right to buy) 1,529 243.53 372.4K 1,529 D
2025-03-03 Greenstreet Yvonne Director / Officer S-Sale D Common Stock 4 248.36 993.44 98,635 D
2025-03-03 Garg Pushkal Officer S-Sale D Common Stock 1 248.36 248.36 26,323 D
2025-03-03 Fitzgerald Kevin Joseph Officer S-Sale D Common Stock 487 243.94 118.8K 14,564 D
2025-02-28 Tanguler Tolga Officer S-Sale D Common Stock 23 239.18 5.5K 14,785 D
2025-02-28 Poulton Jeffrey V. Officer S-Sale D Common Stock 35 239.18 8.4K 34,583 D
2025-02-28 Greenstreet Yvonne Director / Officer S-Sale D Common Stock 440 243.23 107.0K 84,761 D
2025-02-28 Garg Pushkal Officer S-Sale D Common Stock 91 240.32 21.9K 13,674 D
2025-02-28 Fitzgerald Kevin Joseph Officer S-Sale D Common Stock 37 244.11 9.0K 12,385 D
2025-02-27 Tanguler Tolga Officer M-Exempt A Common Stock 1,667 0.00 14,858 D
2025-02-27 Poulton Jeffrey V. Officer M-Exempt D Restricted Stock Units 1,908 0.00 1,908 D
2025-02-27 Greenstreet Yvonne Director / Officer M-Exempt A Common Stock 5,921 0.00 87,447 D
2025-02-27 Garg Pushkal Officer M-Exempt D Restricted Stock Units 1,908 0.00 1,908 D
2025-02-18 Garg Pushkal Officer S-Sale D Common Stock 862 250.11 215.6K 12,675 D
2025-02-18 Fitzgerald Kevin Joseph Officer S-Sale D Common Stock 1,086 250.21 271.7K 13,235 D
2025-02-14 Poulton Jeffrey V. Officer S-Sale D Common Stock 37 261.45 9.7K 32,823 D
2025-02-14 Greenstreet Yvonne Director / Officer S-Sale D Common Stock 271 252.50 68.4K 82,468 D
2025-02-14 Garg Pushkal Officer S-Sale D Common Stock 32 264.87 8.5K 13,537 D
2025-02-14 Fitzgerald Kevin Joseph Officer S-Sale D Common Stock 47 255.56 12.0K 14,518 D
2025-02-13 Poulton Jeffrey V. Officer A-Award A Common Stock 3,109 0.00 33,753 D
2025-02-13 Greenstreet Yvonne Director / Officer A-Award A Common Stock 3,859 0.00 82,739 D
2025-02-13 Garg Pushkal Officer A-Award A Common Stock 3,109 0.00 15,098 D
2025-02-13 Fitzgerald Kevin Joseph Officer A-Award A Common Stock 2,103 0.00 14,984 D
2025-01-27 Garg Pushkal Officer M-Exempt A Common Stock 25,000 88.95 2.22M 64,581 D
2025-01-23 SHARP PHILLIP A Director M-Exempt A Common Stock 11,250 131.21 1.48M 11,250 D
2024-12-12 Garg Pushkal Officer S-Sale D Common Stock 426 250.08 106.5K 16,724 D
2024-11-27 Fitzgerald Kevin Joseph Officer S-Sale D Common Stock 110 254.48 28.0K 12,881 D
2024-11-26 Tanguler Tolga Officer S-Sale D Common Stock 84 252.27 21.2K 13,191 D
2024-11-26 Poulton Jeffrey V. Officer S-Sale D Common Stock 945 251.42 237.6K 30,741 D
2024-11-26 Greenstreet Yvonne Director / Officer S-Sale D Common Stock 93 247.77 23.0K 84,006 D
2024-11-26 Garg Pushkal Officer S-Sale D Common Stock 246 249.60 61.4K 18,863 D
2024-11-26 Fitzgerald Kevin Joseph Officer S-Sale D Common Stock 318 250.68 79.7K 15,322 D
2024-11-25 Tanguler Tolga Officer A-Award A Common Stock 3,000 0.00 14,660 D
2024-11-25 Poulton Jeffrey V. Officer A-Award A Common Stock 3,434 0.00 32,326 D
2024-11-25 Greenstreet Yvonne Director / Officer A-Award A Common Stock 10,658 0.00 84,099 D
2024-11-25 Garg Pushkal Officer A-Award A Common Stock 3,434 0.00 19,139 D
2024-11-25 Fitzgerald Kevin Joseph Officer A-Award A Common Stock 3,000 0.00 15,881 D
2024-10-17 Reitan Colleen F Director P-Purchase A Common Stock 4 302.67 1.2K 36 D
2024-10-08 Garg Pushkal Officer A-Award A Common Stock 96 0.00 15,705 D
2024-10-01 Hesslein Robert W. Officer A-Award A Common Stock 7,245 0.00 7,245 D
2024-09-30 Hesslein Robert W. Officer 0 0.00 0
2024-08-29 Reitan Colleen F Director P-Purchase A Common Stock 32 286.00 9.2K 32 D
2024-08-20 Greenstreet Yvonne Director / Officer M-Exempt A Common Stock 15,000 85.00 1.28M 88,441
2024-08-12 Fitzgerald Kevin Joseph Officer S-Sale D Common Stock 5,736 271.32 1.56M 18,087
2024-08-06 Ausiello Dennis A Director M-Exempt A Common Stock 9,000 105.26 947.3K 20,386
2024-08-01 Greenstreet Yvonne Director / Officer S-Sale D Common Stock 15,148 270.00 4.09M 73,441
2024-07-11 Greenstreet Yvonne Director / Officer S-Sale D Common Stock 7,093 261.00 1.85M 73,441
2024-06-25 Tanguler Tolga Officer S-Sale D Common Stock 129 228.30 29.5K 13,012
2024-06-25 SCHULMAN AMY W Director M-Exempt A Common Stock 8,500 131.21 1.12M 16,936
2024-06-25 Poulton Jeffrey V. Officer S-Sale D Common Stock 59 221.71 13.1K 30,438
2024-06-25 Greenstreet Yvonne Director / Officer S-Sale D Common Stock 957 234.66 224.6K 81,397
2024-06-25 Garg Pushkal Officer S-Sale D Common Stock 242 234.66 56.8K 15,828
2024-06-25 Fitzgerald Kevin Joseph Officer S-Sale D Common Stock 26 226.82 5.9K 15,286
2024-06-24 Tanguler Tolga Officer A-Award A Common Stock 3,278 0.00 13,265
2024-06-24 Poulton Jeffrey V. Officer A-Award A Common Stock 3,278 0.00 30,497
2024-06-24 PYOTT DAVID E I Director M-Exempt D Stock Option (right to buy) 17,560 88.95 1.56M 7,440
2024-06-24 Greenstreet Yvonne Director / Officer A-Award A Common Stock 16,953 0.00 88,835
2024-06-24 Garg Pushkal Officer A-Award A Common Stock 4,295 0.00 17,712
2024-06-24 Fitzgerald Kevin Joseph Officer A-Award A Common Stock 2,498 0.00 15,379
2024-05-29 SCHULMAN AMY W Director S-Sale D Common Stock 11,516 148.93 1.72M 8,499
2024-05-16 Sigal Charles Elliott Director A-Award A Stock Option (right to buy) 5,228 151.22 790.6K 5,228
2024-05-16 SHARP PHILLIP A Director A-Award A Stock Option (right to buy) 5,228 151.22 790.6K 5,228
2024-05-16 SCHULMAN AMY W Director A-Award A Stock Option (right to buy) 5,228 151.22 790.6K 5,228
2024-05-16 Reitan Colleen F Director A-Award A Stock Option (right to buy) 5,228 151.22 790.6K 5,228
2024-05-16 PYOTT DAVID E I Director A-Award A Stock Option (right to buy) 5,228 151.22 790.6K 5,228
2024-05-16 KELLOGG PETER N Director A-Award A Stock Option (right to buy) 5,228 151.22 790.6K 5,228
2024-05-16 HAMBURG MARGARET A Director A-Award A Stock Option (right to buy) 5,228 151.22 790.6K 5,228
2024-05-16 Bertozzi Carolyn R Director A-Award A Stock Option (right to buy) 5,228 151.22 790.6K 5,228
2024-05-16 BRANDICOURT OLIVIER Director A-Award A Stock Option (right to buy) 5,228 151.22 790.6K 5,228
2024-05-16 BONNEY MICHAEL W Director A-Award A Stock Option (right to buy) 5,228 151.22 790.6K 5,228
2024-05-16 Ausiello Dennis A Director A-Award A Stock Option (right to buy) 5,228 151.22 790.6K 5,228
2024-03-20 Fitzgerald Kevin Joseph Officer D Stock Option (right to buy) 14,580 118.05 1.72M 0
2024-03-01 Tanguler Tolga Officer A-Award A Common Stock 4,751 0.00 9,987
2024-03-01 Poulton Jeffrey V. Officer A-Award A Stock Option (right to buy) 15,118 152.61 2.31M 15,118
2024-03-01 Greenstreet Yvonne Director / Officer A-Award A Stock Option (right to buy) 46,394 152.61 7.08M 46,394
2024-03-01 Garg Pushkal Officer A-Award A Stock Option (right to buy) 9,279 152.61 1.42M 9,279
2024-02-29 SHARP PHILLIP A Director S-Sale D Common Stock 915 152.40 139.4K 2,523
2024-02-28 Tanguler Tolga Officer S-Sale D Common Stock 216 154.54 33.4K 5,521
2024-02-28 Poulton Jeffrey V. Officer S-Sale D Common Stock 1 158.09 158.09 19,478
2024-02-28 Greenstreet Yvonne Director / Officer S-Sale D Common Stock 588 156.38 92.0K 48,220
2024-02-28 Garg Pushkal Officer S-Sale D Common Stock 17 157.30 2.7K 8,667
2024-02-28 Franchini Indrani Lall Officer S-Sale D Common Stock 142 154.54 21.9K 4,320
2024-02-27 Tanguler Tolga Officer M-Exempt A Common Stock 1,667 0.00 5,737
2024-02-27 Poulton Jeffrey V. Officer M-Exempt D Restricted Stock Units 1,908 0.00 3,816
2024-02-27 Greenstreet Yvonne Director / Officer M-Exempt A Common Stock 5,921 0.00 51,060
2024-02-27 Garg Pushkal Officer M-Exempt D Restricted Stock Units 1,908 0.00 3,816
2024-02-27 Franchini Indrani Lall Officer M-Exempt D Restricted Stock Units 878 0.00 1,754
2024-02-16 Tanguler Tolga Officer S-Sale D Common Stock 121 149.03 18.0K 4,070
2024-02-16 Poulton Jeffrey V. Officer S-Sale D Common Stock 518 148.24 76.8K 18,264
2024-02-16 Greenstreet Yvonne Director / Officer S-Sale D Common Stock 840 149.03 125.2K 45,139
2024-02-16 Garg Pushkal Officer S-Sale D Common Stock 156 149.03 23.2K 7,332
2024-02-15 Tanguler Tolga Officer A-Award A Common Stock 3,278 0.00 5,079
2024-02-15 Poulton Jeffrey V. Officer A-Award A Common Stock 3,278 0.00 19,151
2024-02-15 Greenstreet Yvonne Director / Officer A-Award A Common Stock 16,953 0.00 52,169
2024-02-15 Garg Pushkal Officer A-Award A Common Stock 4,295 0.00 8,640
2024-02-02 Franchini Indrani Lall Officer S-Sale D Common Stock 269 172.38 46.4K 3,584
2024-02-01 Franchini Indrani Lall Officer M-Exempt D Restricted Stock Units 5,175 0.00 5,175

Executive team

Top executives
EBIT / Employee
224.9K
Shares Outstanding
133.43M

Executive compensation

Executive compensation (annual)
# Year Executive Salary Bonus Stock award Option award Incentive Other Total % Stock-
based
Filing
1 2025 Yvonne L. Greenstreet, M.D. Chief Executive Officer (principal executive officer) 1.40M 5.51M 4.36M 3.56M 25.0K 14.87M 66.43%
2 2025 Jeffrey V. Poulton Executive Vice President, Chief Financial Officer (principal financial officer) 724.4K 3.99M 1.18M 950.3K 22.4K 6.86M 75.27%
3 2025 Bryan A. Supran Executive Vice President, Chief Legal Officer and Secretary 190.4K 350.0K 6.00M 214.8K 90.7K 6.85M 87.64%
4 2025 Pushkal Garg, M.D. Executive Vice President, Chief Research and Development Officer 767.9K 3.69M 940.1K 1.07M 22.4K 6.49M 71.30%
5 2025 Tolga Tanguler Executive Vice President, Chief Commercial Officer 698.0K 3.69M 940.1K 783.2K 20.1K 6.13M 75.50%
6 2024 Yvonne L. Greenstreet, M.D. Chief Executive Officer (principal executive officer) 1.25M 3.63M 3.61M 2.98M 24.8K 11.49M 62.99%
7 2024 Jeffrey V. Poulton Executive Vice President, Chief Financial Officer (principal financial officer) 687.4K 1.18M 1.18M 724.2K 22.2K 3.79M 62.20%
8 2024 Pushkal Garg, M.D. Executive Vice President, Chief Research and Development Officer 682.1K 775.2K 722.9K 716.9K 22.2K 2.92M 51.32%
9 2024 Pushkal Garg, M.D. Executive Vice President, Chief Medical Officer 682.1K 775.2K 722.9K 716.9K 22.2K 2.92M 51.32%
10 2024 Tolga Tanguler Executive Vice President, Chief Commercial Officer 627.4K 725.0K 722.9K 659.4K 19.9K 2.75M 52.56%
11 2024 Kevin J. Fitzgerald, Ph.D. Executive Vice President, Chief Scientific Officer 586.6K 725.0K 722.9K 616.6K 22.2K 2.67M 54.16%
12 2023 Yvonne L. Greenstreet, MBChB, MBA Chief Executive Officer (principal executive officer) 975.8K 3.38M 3.37M 1.16M 20.7K 8.90M 75.81%
13 2023 Yvonne L. Greenstreet, M.D. Chief Executive Officer (principal executive officer) 975.8K 3.38M 3.37M 1.16M 20.7K 8.90M 75.81%
14 2023 Akshay K. Vaishnaw, M.D., Ph.D. Former President 647.8K 1.10M 1.10M 450.5K 20.7K 3.32M 66.27%
15 2023 Pushkal Garg, M.D. Executive Vice President, Chief Medical Officer 656.9K 1.09M 1.09M 382.9K 18.1K 3.23M 67.26%
16 2023 Pushkal Garg, M.D. Executive Vice President, Chief Research and Development Officer 656.9K 1.09M 1.09M 382.9K 18.1K 3.23M 67.26%
17 2023 Jeffrey V. Poulton Executive Vice President, Chief Financial Officer (principal financial officer) 651.9K 1.09M 1.09M 381.2K 18.1K 3.22M 67.40%
18 2023 Tolga Tanguler Executive Vice President, Chief Commercial Officer 603.2K 950.1K 948.4K 352.3K 15.8K 2.87M 66.15%
19 2023 Kevin J. Fitzgerald, Ph.D. Executive Vice President, Chief Scientific Officer 539.6K 950.1K 948.4K 329.2K 18.0K 2.79M 68.16%
20 2023 Indrani L. Franchini, J.D. Executive Vice President, Chief Legal Officer 594.3K 500.1K 499.2K 344.8K 31.6K 1.97M 50.73%
21 2022 Indrani L. Franchini, J.D. Executive Vice President, Chief Legal Officer and Secretary 535.4K 2.25M 2.25M 333.5K 41.3K 5.41M 83.17%
22 2022 Indrani L. Franchini, J.D. Executive Vice President, Chief Legal Officer 535.4K 2.25M 2.25M 333.5K 41.3K 5.41M 83.17%
23 2022 Yvonne L. Greenstreet, MBChB, MBA Chief Executive Officer (principal executive officer) 850.0K 2.50M 977.5K 262.5K 4.59M 54.45%
24 2022 Yvonne L. Greenstreet, M.D. Chief Executive Officer (principal executive officer) 850.0K 2.50M 977.5K 262.5K 4.59M 54.45%
25 2022 Akshay K. Vaishnaw, M.D., Ph.D. Former President 725.0K 2.35M 500.3K 17.5K 3.59M 65.40%
26 2022 Akshay K. Vaishnaw, M.D., Ph.D. President 725.0K 2.35M 500.3K 17.5K 3.59M 65.40%
27 2022 Pushkal P. Garg, M.D. Chief Medical Officer and Executive Vice President, Development Medical Affairs 625.0K 1.90M 359.4K 17.1K 2.90M 65.47%
28 2022 Pushkal Garg, M.D. Executive Vice President, Chief Medical Officer 625.0K 1.90M 359.4K 17.1K 2.90M 65.47%
29 2022 Kevin J. Fitzgerald, Ph.D. Executive Vice President, Chief Scientific Officer 493.7K 1.60M 330.6K 17.1K 2.45M 65.60%
30 2022 Jeffrey V. Poulton Executive Vice President, Chief Financial Officer (principal financial officer) 604.5K 1.45M 350.8K 17.1K 2.42M 59.85%
31 2022 Tolga Tanguler Executive Vice President, Chief Commercial Officer 564.8K 1.45M 326.4K 11.6K 2.35M 61.62%
32 2021 John M. Maraganore, Ph.D. Former Chief Executive Officer (principal executive officer) 948.5K 7.86M 1.10M 271.1K 10.18M 77.25%
33 2021 Yvonne L. Greenstreet, MBChB, MBA President and Chief Operating Officer 619.1K 7.34M 429.1K 186.0K 8.58M 85.61%
34 2021 Yvonne L. Greenstreet, MBChB, MBA Chief Executive Officer (principal executive officer) 619.1K 7.34M 429.1K 186.0K 8.58M 85.61%
35 2021 Tolga Tanguler Executive Vice President, Chief Commercial Officer 547.9K 1.50M 4.50M 316.3K 11.7K 6.88M 87.26%
36 2021 Akshay K. Vaishnaw, M.D., Ph.D. President, Research and Development 632.2K 4.34M 438.2K 14.9K 5.43M 80.00%
37 2021 Akshay K. Vaishnaw, M.D., Ph.D. Former President 632.2K 4.34M 438.2K 14.9K 5.43M 80.00%
38 2021 Akshay K. Vaishnaw, M.D., Ph.D. President 632.2K 4.34M 438.2K 14.9K 5.43M 80.00%
39 2021 Pushkal Garg, M.D. Executive Vice President, Chief Medical Officer 568.9K 3.08M 380.2K 14.2K 4.05M 76.20%
40 2021 Pushkal P. Garg, M.D. Chief Medical Officer and Executive Vice President, Development Medical Affairs 568.9K 3.08M 380.2K 14.2K 4.05M 76.20%
41 2021 Jeffrey V. Poulton Executive Vice President, Chief Financial Officer (principal financial officer) 569.2K 1.88M 330.6K 14.2K 2.80M 67.33%
42 2020 Barry E. Greene Former President 484.0K 457.6K 8.31M 376.4K 717.3K 10.35M 84.75%
43 2020 John M. Maraganore, Ph.D. Former Chief Executive Officer (principal executive officer) 946.2K 5.75M 1.11M 15.7K 7.82M 73.50%
44 2020 John M. Maraganore, Ph.D. Chief Executive Officer (principal executive officer) 946.2K 5.75M 1.11M 15.7K 7.82M 73.50%
45 2020 Yvonne L. Greenstreet, MBChB, MBA President and Chief Operating Officer 621.5K 1.80M 434.7K 178.9K 3.03M 59.29%
46 2020 Yvonne L. Greenstreet, MBChB, MBA Chief Executive Officer (principal executive officer) 621.5K 1.80M 434.7K 178.9K 3.03M 59.29%
47 2020 Akshay K. Vaishnaw, M.D., Ph.D. President 634.6K 1.80M 443.9K 14.9K 2.89M 62.20%
48 2020 Akshay K. Vaishnaw, M.D., Ph.D. President, Research and Development 634.6K 1.80M 443.9K 14.9K 2.89M 62.20%
49 2020 Pushkal P. Garg, M.D. Chief Medical Officer and Executive Vice President, Development Medical Affairs 553.2K 1.70M 321.4K 14.2K 2.59M 65.65%
50 2020 Jeffrey V. Poulton Executive Vice President, Chief Financial Officer (principal financial officer) 556.8K 1.60M 322.6K 14.6K 2.49M 64.14%
51 2020 Laurie B. Keating Executive Vice President, Chief Legal Officer and Secretary 544.6K 1.60M 265.0K 25.6K 2.43M 65.69%
52 2019 John M. Maraganore, Ph.D. Chief Executive Officer (principal executive officer) 845.0K 1.20M 4.33M 913.8K 27.8K 7.32M 75.59%
53 2019 John M. Maraganore, Ph.D. Former Chief Executive Officer (principal executive officer) 845.0K 1.20M 4.33M 913.8K 27.8K 7.32M 75.59%
54 2019 Jeffrey V. Poulton Executive Vice President, Chief Financial Officer (principal financial officer) 254.8K 5.48M 136.7K 6.3K 5.88M 93.23%
55 2019 Manmeet S. Soni Former Senior Vice President, Chief Financial Officer (former principal financial officer) 314.4K 283.4K 2.02M 694.5K 3.31M 69.51%
56 2019 Yvonne L. Greenstreet, MBChB, MBA Chief Operating Officer 571.4K 460.4K 1.65M 370.9K 192.9K 3.25M 65.07%
57 2019 Yvonne L. Greenstreet, MBChB, MBA President and Chief Operating Officer 571.4K 460.4K 1.65M 370.9K 192.9K 3.25M 65.07%
58 2019 Barry E. Greene Former President 596.8K 460.4K 1.65M 385.3K 21.4K 3.12M 67.82%
59 2019 Barry E. Greene President 596.8K 460.4K 1.65M 385.3K 21.4K 3.12M 67.82%
60 2019 Akshay K. Vaishnaw, M.D., Ph.D. President, Research and Development 586.5K 460.4K 1.65M 378.7K 20.9K 3.10M 68.20%
61 2019 Laurie B. Keating Executive Vice President, Chief Legal Officer and Secretary 490.4K 354.1K 1.27M 268.8K 35.7K 2.42M 67.18%
62 2018 John M. Maraganore, Ph.D. Chief Executive Officer (principal executive officer) 800.0K 3.78M 480.0K 27.0K 5.09M 74.32%
63 2018 Barry E. Greene President 580.0K 2.16M 232.0K 21.1K 2.99M 72.18%
64 2018 Barry E. Greene Former President 580.0K 2.16M 232.0K 21.1K 2.99M 72.18%
65 2018 Yvonne L. Greenstreet, MBChB, MBA President and Chief Operating Officer 540.0K 1.80M 216.0K 125.7K 2.68M 67.13%
66 2018 Yvonne L. Greenstreet, MBChB, MBA Chief Operating Officer 540.0K 1.80M 216.0K 125.7K 2.68M 67.13%
67 2018 Akshay K. Vaishnaw, M.D., Ph.D. President, Research and Development 570.0K 1.80M 228.0K 20.6K 2.62M 68.75%
68 2018 Laurie B. Keating Executive Vice President, Chief Legal Officer and Secretary 446.7K 990.6K 144.0K 32.7K 1.61M 61.37%
69 2018 Manmeet S. Soni Senior Vice President, Chief Financial Officer (principal financial officer) 500.0K 50.0K 643.9K 160.0K 9.8K 1.36M 47.22%
70 2018 Manmeet S. Soni Former Senior Vice President, Chief Financial Officer (former principal financial officer) 500.0K 50.0K 643.9K 160.0K 9.8K 1.36M 47.22%
71 2017 Manmeet S. Soni Former Senior Vice President, Chief Financial Officer (former principal financial officer) 318.5K 100.0K 3.85M 165.6K 44.2K 4.48M 85.98%
72 2017 Manmeet S. Soni Senior Vice President, Chief Financial Officer (principal financial officer) 318.5K 100.0K 3.85M 165.6K 44.2K 4.48M 85.98%
73 2017 John M. Maraganore, Ph.D. Chief Executive Officer (principal executive officer) 753.5K 636.7K 27.1K 1.42M 0.00%
74 2017 Yvonne L. Greenstreet, MBChB, MBA Executive Vice President, Chief Operating Officer 504.2K 327.7K 152.7K 984.7K 0.00%
75 2017 Yvonne L. Greenstreet, MBChB, MBA Chief Operating Officer 504.2K 327.7K 152.7K 984.7K 0.00%
76 2017 Barry E. Greene President 562.8K 365.8K 15.5K 944.1K 0.00%
77 2017 Akshay K. Vaishnaw, M.D., Ph.D. President, Research and Development 542.1K 352.4K 20.7K 915.2K 0.00%
78 2017 Michael P. Mason Vice President of Finance and Treasurer (former principal financial officer) 318.3K 124.1K 8.9K 451.4K 0.00%
79 2017 David-Alexandre C. Gros, M.D. Former Senior Vice President, Chief Business Officer (former principal financial officer) 8.3K 8.5K 16.9K 0.00%
80 2016 Yvonne L. Greenstreet, MBChB Executive Vice President, Chief Operating Officer 144.2K 100.0K 5.65M 56.0K 40.4K 5.99M 94.31%
81 2016 Yvonne L. Greenstreet, MBChB, MBA Chief Operating Officer 144.2K 100.0K 5.65M 56.0K 40.4K 5.99M 94.31%
82 2016 Yvonne L. Greenstreet, MBChB, MBA Executive Vice President, Chief Operating Officer 144.2K 100.0K 5.65M 56.0K 40.4K 5.99M 94.31%
83 2016 John M. Maraganore, Ph.D. Chief Executive Officer (principal executive officer) 731.6K 621.0K 380.4K 11.9K 1.74M 35.59%
84 2016 Akshay K. Vaishnaw, M.D., Ph.D. President, Research and Development 526.4K 787.8K 210.5K 10.1K 1.53M 51.33%
85 2016 Akshay K. Vaishnaw, M.D., Ph.D. E xecutive Vice President, Research and Development 526.4K 787.8K 210.5K 10.1K 1.53M 51.33%
86 2016 Barry E. Greene President 546.4K 621.0K 218.6K 10.2K 1.40M 44.48%
87 2016 David-Alexandre C. Gros, M.D. Former Senior Vice President, Chief Business Officer (former principal financial officer) 432.3K 100.0K 621.0K 138.3K 1.6K 1.29M 48.02%
88 2016 Michael P. Mason Vice President of Finance and Treasurer (former principal financial officer) 309.1K 318.3K 137.9K 74.2K 6.7K 846.1K 53.91%
89 2016 Michael P. Mason Vice President of Finance and Treasurer (principal financial officer) 309.1K 318.3K 137.9K 74.2K 6.7K 846.1K 53.91%
90 2015 David-Alexandre C. Gros, M.D. Senior Vice President, Chief Business Officer 241.1K 200.0K 9.63M 95.8K 508.00 10.17M 94.71%
91 2015 David-Alexandre C. Gros, M.D. Former Senior Vice President, Chief Business Officer (former principal financial officer) 241.1K 200.0K 9.63M 95.8K 508.00 10.17M 94.71%
92 2015 John M. Maraganore, Ph.D. Chief Executive Officer (principal executive officer) 710.3K 7.12M 419.8K 7.6K 8.26M 86.23%
93 2015 Barry E. Greene President 530.5K 4.47M 261.2K 7.9K 5.26M 84.81%
94 2015 Barry E. Greene President and Chief Operating Officer 530.5K 4.47M 261.2K 7.9K 5.26M 84.81%
95 2015 Akshay K. Vaishnaw, M.D., Ph.D. Executive Vice President, Research and Development and Chief Medical Officer 500.1K 3.32M 251.7K 7.6K 4.08M 81.37%
96 2015 Akshay K. Vaishnaw, M.D., Ph.D. President, Research and Development 500.1K 3.32M 251.7K 7.6K 4.08M 81.37%
97 2015 Akshay K. Vaishnaw, M.D., Ph.D. E xecutive Vice President, Research and Development 500.1K 3.32M 251.7K 7.6K 4.08M 81.37%
98 2015 Michael P. Mason Vice President of Finance and Treasurer (principal financial officer) 300.0K 1.21M 88.7K 6.3K 1.61M 75.41%
99 2015 Michael P. Mason Vice President of Finance and Treasurer (former principal financial officer) 300.0K 1.21M 88.7K 6.3K 1.61M 75.41%
100 2014 Laurie B. Keating Senior Vice President, General Counsel and Secretary 110.8K 100.0K 5.04M 57.0K 1.7K 5.31M 94.92%
101 2014 John M. Maraganore, Ph.D. Chief Executive Officer (principal executive officer) 689.6K 444.0K 7.6K 1.14M 0.00%
102 2014 Barry E. Greene President 515.0K 276.0K 8.0K 799.0K 0.00%
103 2014 Barry E. Greene President and Chief Operating Officer 515.0K 276.0K 8.0K 799.0K 0.00%
104 2014 Akshay K. Vaishnaw, M.D., Ph.D. Executive Vice President, Research and Development and Chief Medical Officer 463.5K 249.0K 7.6K 720.1K 0.00%
105 2014 Akshay K. Vaishnaw, M.D., Ph.D. E xecutive Vice President, Research and Development 463.5K 249.0K 7.6K 720.1K 0.00%
106 2014 Michael P. Mason Vice President of Finance and Treasurer (principal financial officer) 257.2K 82.0K 6.2K 345.4K 0.00%
107 2013 John M. Maraganore, Ph.D. Chief Executive Officer (principal executive officer) 669.5K 5.13M 431.8K 7.6K 6.24M 82.22%
108 2013 Barry E. Greene President and Chief Operating Officer 500.0K 3.21M 268.8K 7.7K 3.98M 80.51%
109 2013 Akshay K. Vaishnaw, M.D., Ph.D. Executive Vice President, Research and Development and Chief Medical Officer 450.0K 1.05M 241.9K 7.6K 1.75M 59.98%
110 2013 Akshay K. Vaishnaw, M.D., Ph.D. Executive Vice President and Chief Medical Officer 450.0K 1.05M 241.9K 7.6K 1.75M 59.98%
111 2013 Laurence E. Reid, Ph.D. Senior Vice President and Chief Business Officer 375.0K 25.0K 645.2K 161.3K 7.2K 1.21M 53.16%
112 2013 Michael P. Mason Vice President of Finance and Treasurer (principal financial officer) 252.1K 161.3K 81.3K 6.1K 500.9K 32.20%
113 2012 John M. Maraganore, Ph.D. Chief Executive Officer (principal executive officer) 669.5K 1.42M 313.3K 8.8K 2.42M 58.96%
114 2012 Barry E. Greene President and Chief Operating Officer 475.0K 949.6K 195.0K 20.7K 1.64M 57.89%
115 2012 Akshay K. Vaishnaw, M.D., Ph.D. Executive Vice President, Research and Development and Chief Medical Officer 423.3K 132.2K 474.8K 175.5K 6.4K 1.21M 50.07%
116 2012 Akshay K. Vaishnaw, M.D., Ph.D. Executive Vice President and Chief Medical Officer 423.3K 132.2K 474.8K 175.5K 6.4K 1.21M 50.07%
117 2012 Laurence E. Reid, Ph.D. Senior Vice President and Chief Business Officer 338.7K 25.0K 112.9K 379.8K 105.7K 5.9K 967.9K 50.91%
118 2012 Michael P. Mason Vice President of Finance and Treasurer (principal financial officer) 247.2K 82.4K 95.0K 57.8K 6.2K 488.6K 36.30%
119 2011 John M. Maraganore, Ph.D. Chief Executive Officer (principal executive officer) 595.1K 561.3K 229.9K 11.9K 1.40M 40.15%
120 2011 Akshay K. Vaishnaw, M.D., Ph.D. Executive Vice President and Chief Medical Officer 373.9K 637.8K 105.1K 6.5K 1.12M 56.78%
121 2011 Barry E. Greene President and Chief Operating Officer 436.8K 374.2K 128.7K 12.7K 952.5K 39.29%
122 2011 Laurence E. Reid, Ph.D. Senior Vice President and Chief Business Officer 328.8K 25.0K 149.7K 64.8K 5.9K 574.2K 26.07%
123 2011 Michael P. Mason Vice President of Finance and Treasurer (principal financial officer) 238.1K 202.7K 43.7K 6.2K 490.6K 41.31%
124 2005 John M. Maraganore, Ph.D. President and Chief Executive Officer 370.0K 370.0K 0.00%
125 2005 Vincent J. Miles, Ph.D. Senior Vice President, Business Development 241.9K 84.4K 326.3K 0.00%
126 2005 Barry E. Greene Chief Operating Officer 265.2K 15.0K 280.2K 0.00%
127 2004 John M. Maraganore, Ph.D. President and Chief Executive Officer 370.0K 370.0K 0.00%
128 2004 Thomas R. Ulich, M.D. Former Senior Vice President, Research 183.0K 130.7K 313.7K 0.00%
129 2004 Vincent J. Miles, Ph.D. Senior Vice President, Business Development 237.1K 44.5K 281.6K 0.00%
130 2004 Vincent J. Miles, Ph.D. Senior Vice President, Business 237.1K 44.5K 281.6K 0.00%
131 2004 Barry E. Greene Chief Operating Officer and Treasurer 260.0K 260.0K 0.00%
132 2004 Barry E. Greene Chief Operating Officer 260.0K 260.0K 0.00%
133 2004 John G. Conley Former Chief Financial Officer and Vice 21.7K 130.0K 151.7K 0.00%
134 2003 John M. Maraganore, Ph.D. President and Chief Executive Officer 369.4K 110.0K 479.4K 0.00%
135 2003 John G. Conley Former Chief Financial Officer and Vice 259.5K 55.3K 314.7K 0.00%
136 2003 Thomas R. Ulich, M.D. Former Senior Vice President, Research 157.4K 46.1K 43.5K 247.0K 0.00%
137 2003 Vincent J. Miles, Ph.D. Senior Vice President, Business Development 107.7K 45.0K 152.7K 0.00%
138 2003 Vincent J. Miles, Ph.D. Senior Vice President, Business 107.7K 45.0K 152.7K 0.00%
139 2003 Barry E. Greene Chief Operating Officer 53.3K 58.8K 112.1K 0.00%
140 2003 Barry E. Greene Chief Operating Officer and Treasurer 53.3K 58.8K 112.1K 0.00%
CEO compensation breakdown

Proxy statements

Proxy statements (DEF 14A)
Filing date Form type Filing
2026-04-06 DEFA14A
2026-04-06 DEF 14A
2025-04-04 DEFA14A
2025-03-24 DEFA14A
2025-03-24 DEF 14A

Recent SEC filings

Recent SEC filings
Filing date Form type Filing
2026-05-06 SC 13G/A
2026-04-30 8-K
2026-04-30 10-Q
2026-04-29 SC 13G
2026-04-07 4
2026-04-07 3
2026-04-06 DEFA14A
2026-04-06 DEF 14A
2026-04-06 ARS
2026-03-26 SC 13G/A

Executive team

NameTitleCompensationGender
Yvonne L. Greenstreet Chief Executive Officer & Director 5M
Pushkal Garg Executive VP & Chief Research & Development Officer 2M
Jeffrey V. Poulton Chief Financial Officer & Executive Vice President 2M male
Tolga Tanguler Executive Vice President & Chief Commercial Officer 2M male
Kevin Joseph Fitzgerald Executive Vice President, Chief Scientific Officer and Head of Early Research & Early Development 1M
Bryan Andrew Supran Chief Legal Officer 845.9K male
Phillip A. Sharp Co-Founder, Member of the Scientific Advisory Board 52.9K
Piyush Sharma Chief Ethics & Compliance Officer male
Muthiah Manoharan Senior Vice President of Innovation Chemistry & Distinguished Scientist and Member of Scientific Advisory Board
Timothy J. Maines Chief Technical Operations & Quality Officer male
Melissa McLaughlin Chief Human Resources Officer female
Christine Regan Akinc Chief Corporate Communications Officer female
ESG Rating
B
BIOTECHNOLOGY
2014
E (Environmental)
60.9 / 56.3
Company / Sector avg.
S (Social)
64.4 / 62.4
Company / Sector avg.
G (Governance)
61.4 / 60.9
Company / Sector avg.
ESG Total
62.2 / 59.9
Company / Sector avg.
ESG Score History BIOTECHNOLOGY
Benchmark vs Sector
Political Trading Activity (25M)
Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity
Transaction Date Disclosed Representative District Owner Type Amount Link
2025-05-12 2025-06-23 Jefferson Shreve IN06 Sale $15,001 - $50,000
2024-01-29 2024-02-15 Josh Gottheimer NJ05 Joint Sale (Full) $1,001 - $15,000
2024-01-11 2024-02-15 Josh Gottheimer NJ05 Joint Purchase $1,001 - $15,000
2023-12-11 2024-01-07 Josh Gottheimer NJ05 Joint Sale $1,001 - $15,000
2023-03-06 2023-04-17 Daniel Goldman NY10 Purchase $15,001 - $50,000
2023-02-10 2023-03-08 Ro Khanna CA17 Spouse Sale $1,001 - $15,000
2023-01-31 2023-02-24 Daniel Goldman NY10 Sale $15,001 - $50,000
2022-12-06 2023-01-03 Ro Khanna CA17 Spouse Purchase $1,001 - $15,000
2022-09-28 2022-10-16 Josh Gottheimer NJ05 Joint Purchase $1,001 - $15,000
2020-11-13 2020-12-09 Josh Gottheimer NJ05 Joint Sale (Full) $1,001 - $15,000
2020-04-06 2020-05-13 Josh Gottheimer NJ05 Joint Purchase $1,001 - $15,000
2018-10-18 2018-11-16 Josh Gottheimer NJ05 Joint Sale (Full) $1,001 - $15,000
2018-06-01 2018-10-02 Josh Gottheimer NJ05 Purchase $1,001 - $15,000
Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend history

Earnings history

Earnings reports

Stock splits