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Panacea Life Sciences Holdings, Inc. (PLSH)

USD0.10 +0.00 (+0.00%)
US OTC Healthcare Drug Manufacturers - Specialty & Generic
Address 5910 South University Boulevard 80121
Greenwood Village, CO, US
CEO Leslie A. Buttorff
IPO 2022-04-04
CIK 1552189 ISIN US69810P1093

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Description

Panacea Life Sciences Holdings, Inc. operates as an integrated research and production firm, specializing in cannabinoid and nutraceutical products across the entire supply chain, from sourcing to final sale. Its core mission is to develop and deliver natural, pharmaceutical-grade alternatives for both human and pet consumption. The company's diverse product range encompasses items such as softgels, edible gummies, liquid tinctures, sublingual tablets, and a variety of cosmetic and topical applications. In addition to these offerings, the company is involved in the personal protective equipment (PPE) market, importing and distributing hand sanitizers and masks. Panacea Life Sciences also provides white-label and contract manufacturing services to other cannabinoid companies, sells raw materials, and manages tolling arrangements. Established in 2008, the company is headquartered in Greenwood Village, Colorado.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
USD0.10 +0.00 (+0.00%)
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Volume Profile
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Liquidity & share structure
Average Volume
23.8K
Beta
2.68
Float Shares
10.13M
Free Float %
47.7%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
+5.49% +1.69% -25.56% -33.26% -50.00% -40.00% -40.00% -93.48% -95.71% -95.71% -95.71%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
vs.
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Price Targets & DCF
Current price
0.10
DCF (Unlevered) 0.03 -74.5%

DCF figures are point estimates: small changes in growth or discount-rate assumptions move them materially. Read them as a reference, not a precise target.

Quality scores
Altman Z-Score
-25.46
Distress
Piotroski F-Score
3 / 9
Average
MOAT Score
1 / 10
No MOAT
Composite Rating
C+
Overall Score
2 / 5
Medium
DCF Score
1 / 5
Low
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
3 / 5
Medium
P/E Score
1 / 5
Low
P/Book Score
5 / 5
High
Operational MOAT
✗ Below peers
  • Revenue growth Drug Manufacturers - Specialty & Generic: +6.8%
    -77.8% Q1'26: -80.1% (vs Q1'25)
  • EPS growth Drug Manufacturers - Specialty & Generic: +16.5%
    +77.9% Q1'26: -29,850.0% (vs Q1'25)
  • FCF margin FCF growth · Drug Manufacturers - Specialty & Generic: +32.3%
    -612.9% Q1'26: -85.5% (vs Q1'25)
  • EBIT margin Drug Manufacturers - Specialty & Generic: +13.0%
    -192.6% Q1'26: -126.1% (vs Q1'25)
  • ROIC Drug Manufacturers - Specialty & Generic: +6.5%
    -31.6% Q1'26: -11.0% (vs Q1'25)
  • Share dilution Drug Manufacturers - Specialty & Generic: +0.0%
    +222.7% Q1'26: +195.3% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Drug Manufacturers - Specialty & Generic: -0.10×
    11.81× Q1'26: -1.02× (vs Q1'25)
Valuation Multiples From To
Price Forecast (3Y) From To
Model
Adjust
P/E
Theoretical Return — If Invested Today

* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.

DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (2.64) × ERP
WACC = 89% × Ke + 11% × Kd (449.7%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Intrinsic value (base): 0.03 Current price: 0.10
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2019
actual
Dec 2020
actual
Dec 2025
actual
Dec 2026
1 Rev. Ana.
1 EPS Ana.
Dec 2027
1 Rev. Ana.
1 EPS Ana.
Dec 2028
1 Rev. Ana.
1 EPS Ana.
Revenue
345.7K
est: 1.90M (-81.8%)
9.02M
est: 7.60M (+18.7%)
910.5K
est: 910.5K (+0.0%)
956.0K
956.0K – 956.0K
+5.0% YoY
1.90M
1.90M – 1.90M
+98.7% YoY
7.60M
7.60M – 7.60M
+300.0% YoY
EBITDA
-8.65M
est: -981.9K (-780.7%)
-2.03M
est: -3.93M (+48.4%)
18.2K
est: -425.9K (+104.3%)
-447.2K
-447.2K – -447.2K
-5.0% YoY
-888.8K
-888.8K – -888.8K
-98.7% YoY
-3.56M
-3.56M – -3.56M
-300.0% YoY
EBIT
-9.54M
est: -1.18M (-707.2%)
-3.72M
est: -4.73M (+21.3%)
-1.75M
est: -673.4K (-160.4%)
-707.0K
-707.0K – -707.0K
-5.0% YoY
-1.41M
-1.41M – -1.41M
-98.7% YoY
-5.62M
-5.62M – -5.62M
-300.0% YoY
Net Income
-9.48M
est: -371.50M (+97.4%)
-6.99M
est: -165.11M (+95.8%)
-416.7K
est: -1.47B (+100.0%)
-1.33B
-1.33B – -1.33B
+9.1% YoY
-1.20B
-1.20B – -1.20B
+10.0% YoY
-532.89M
-532.89M – -532.89M
+55.6% YoY
SGA
8.95M
est: 1.39M (+545.0%)
2.81M
est: 5.55M (-49.4%)
533.8K
est: 715.1K (-25.4%)
750.8K
750.8K – 750.8K
+5.0% YoY
1.49M
1.49M – 1.49M
+98.7% YoY
5.97M
5.97M – 5.97M
+300.0% YoY
EPS
-7.83
est: -20.16 (+61.2%)
-0.41
est: -8.96 (+95.4%)
-0.01
est: -24.64 (+100.0%)
-22.40
-22.40 – -22.40
+9.1% YoY
-20.16
-20.16 – -20.16
+10.0% YoY
-8.96
-8.96 – -8.96
+55.6% YoY
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-11 C+ 2/5 1/5 1/5 1/5 3/5 1/5 5/5
2026-05-06 C+ 2/5 1/5 1/5 1/5 3/5 1/5 5/5
2026-05-04 C+ 2/5 1/5 1/5 1/5 3/5 1/5 5/5
2026-04-30 C+ 2/5 1/5 1/5 1/5 3/5 1/5 5/5
2026-04-28 C 2/5 1/5 1/5 1/5 2/5 1/5 5/5
2026-04-27 C 2/5 1/5 1/5 1/5 2/5 1/5 5/5
2026-04-24 C 2/5 1/5 1/5 1/5 2/5 1/5 5/5
2026-04-23 C 2/5 1/5 1/5 1/5 2/5 1/5 5/5
2026-04-22 C 2/5 1/5 1/5 1/5 2/5 1/5 5/5
2026-04-21 C 2/5 1/5 1/5 1/5 2/5 1/5 5/5
2026-04-20 C 2/5 1/5 1/5 1/5 2/5 1/5 5/5
2026-04-17 C 2/5 1/5 1/5 1/5 2/5 1/5 5/5
2026-04-16 C 2/5 1/5 1/5 1/5 2/5 1/5 5/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
-9.04M
OE per share TTM
-0.23
Owner's Yield
-534.39%
Maintenance CapEx ratio
Maint CapEx / Avg PPE
281.0%

Ownership Overview

Ownership breakdown

Ownership breakdown not available.

At a glance
Institutional holders
Total invested
Insider transactions (90d)
0
Beneficial owners (>5%)
10
Beneficial owners (>5%)
# Reporting person Amount owned % of class Sole voting Shared voting Sole dispositive Shared dispositive Type Citizenship Filing date SEC filing
1 22nd Century Group, Inc. 91.02M 15.20% 91.02M CO Nevada 2021-07-09
2 Ceed2Med, LLC 67.09M 57.36% 67.09M 67.09M 10.00 CO 6.  Citizenship or Place of Organization 2019-01-22
3 Paradox Capital Partners, LLC 13.73M 9.99% 13.00M 726.9K 13.00M 726.9K PN 2021-02-08
4 Vladislav (Bobby) Yampolsky 7.64M 22.20% 7.64M 7.64M 10.00 OO or Place of Organization 2019-07-29
5 Real Estate Company, LLC 7.30M 47.00% 7.30M 7.30M CO Colorado 2023-06-23
6 Buttorff 1.54M 9.90% 1.54M 1.54M IN Colorado 2023-06-23
7 Harvey Kesner 326.8K 0.40% 326.8K 326.8K 11.00 IN 2021-02-08
8 Harvey & Renee Kesner JTWROS 250.0K 0.31% 250.0K 250.0K 11.00 IN 2021-02-08
9 Darwin Capital Investments, LLC 150.0K 0.18% 150.0K 150.0K 11.00 PN 2021-02-08
10 Renee Kesner 134.00 0.00% 134.00 134.00 11.00 IN 2021-02-08

Institutional Activity (13F)

Institutional ownership trend

Institutional history not available.

Top institutional holders

Top holders not available.

ETF Ownership

Top ETFs holding this stock

This company is not held by any ETF in our universe.

Insider Activity

Insider Activity — Latest Quarter
Ratio by transactions
0.00
Bearish
Buys
1
Sells
0
Shares acquired
20.0K
Shares disposed
Cash buys
1.00
Cash sales
Net activity
+20,000
Insider buys vs sells (history) From To
Recent insider transactions From To
Date Person Role Transaction A/D Security Shares Price Value Owned after D/I Filing
2023-09-18 Buttorff Leslie Director / Officer / 10% Owner P-Purchase A Common Stock 20,000 0.24 4.7K 1,533,949
2023-06-09 Buttorff Leslie Director / Officer / 10% Owner P-Purchase A Common Stock 3,000 0.43 1.3K 1,513,949
2023-06-02 Buttorff Leslie Director / Officer / 10% Owner A-Award A Common Stock 760,000 0.50 380.0K 1,510,949
2023-05-23 Buttorff Leslie Director / Officer / 10% Owner P-Purchase A Common Stock 500 0.50 249.00 751,449
2023-05-19 Buttorff Leslie Director / Officer / 10% Owner P-Purchase A Common Stock 1,500 0.52 780.00 750,949
2023-05-09 Buttorff Leslie Director / Officer / 10% Owner P-Purchase A Common Stock 2,300 0.38 867.10 741,949
2023-05-08 Buttorff Leslie Director / Officer / 10% Owner P-Purchase A Common Stock 1,500 0.43 645.00 739,649
2023-05-05 Buttorff Leslie Director / Officer / 10% Owner P-Purchase A Common Stock 11,500 0.49 5.6K 738,149
2023-04-26 Buttorff Leslie Director / Officer / 10% Owner P-Purchase A Common Stock 5,500 0.40 2.2K 726,649
2023-04-25 Buttorff Leslie Director / Officer / 10% Owner P-Purchase A Common Stock 3,500 0.38 1.3K 721,149
2023-04-05 Buttorff Leslie Director / Officer / 10% Owner P-Purchase A Common Stock 2,500 0.33 825.00 716,649
2023-04-04 Buttorff Leslie Director / Officer / 10% Owner P-Purchase A Common Stock 3,200 0.35 1.1K 714,149
2023-04-03 Buttorff Leslie Director / Officer / 10% Owner P-Purchase A Common Stock 1,000 0.36 360.00 710,949
2023-02-27 Buttorff Leslie Director / Officer / 10% Owner P-Purchase A Common Stock 1,000 0.19 190.00 709,949
2023-02-26 Buttorff Leslie Director / Officer / 10% Owner P-Purchase A Common Stock 1,000 0.19 190.00 706,949
2022-12-31 Buttorff Leslie Officer I Common Stock 0 0.00 4,047,054
2022-08-26 Buttorff Leslie Officer P-Purchase A Common Stock 11,500 0.14 1.6K 657,449
2022-08-11 Wert Lawrence Director P-Purchase A Common Stock 5,000 0.13 640.00 1,317,868
2022-08-03 Buttorff Leslie Officer P-Purchase A Common Stock 2,600 0.10 260.00 639,349
2022-07-08 Buttorff Leslie Officer P-Purchase A Common Stock 2,100 0.40 835.59 627,149
2022-04-04 Buttorff Leslie Officer P-Purchase A Common Stock 1,404 0.60 842.40 618,399
2021-12-31 Buttorff Leslie Director / Officer / 10% Owner I Series C Preferred Stock 0 0.00 1,000,000
2021-10-17 Nerger Janice Director D Common Stock 0 0.00 1,987,828
2021-06-30 Wert Lawrence Director A-Award A Stock Options (Right to Buy) 28,000,000 0.10 2.80M 28,000,000
2021-06-30 Buttorff Leslie Director / Officer / 10% Owner A-Award A Series D Preferred Stock 10,000 0.00 10,000
2021-06-30 Berman Nathan Joel Officer A-Award A Common Stock 496,957 0.00 496,957
2021-06-30 22nd Century Group, Inc. 10% Owner D Common Stock 0 0.00 91,016,026
2021-05-04 Kesner Harvey J 10% Owner I Common Stock 0 0.00 117,059
2021-03-01 Wert Lawrence Director A-Award A Common Stock 3,500,000 0.00 8,620,297
2021-01-22 Alberttis Alvaro Daniel Director / Officer A-Award A Options to purchase common stock 2,500,000 0.03 62.5K 2,500,000
2020-02-18 Du Chesne Derek Officer D Options to purchase common stock 1,000,000 0.50 500.0K 0
2020-02-01 Puzder Ken Director / Officer A-Award A Common Stock 250,000 0.00 500,000
2020-02-01 Johnson Andrew L. Officer A-Award A Common Stock 250,000 0.00 1,106,250
2020-01-16 Alberttis Alvaro Daniel Director D Common stock 0 0.00 238,096
2019-12-11 Ceed2Med LLC Director / 10% Owner J-Other D Common Stock, Par Value $0.0001 per Share 1,200,000 0.00 6,435,691
2019-11-20 Thompson Jeffrey M Director A-Award A Common Stock 100,000 0.00 100,000
2019-11-20 Price John C Director A-Award A Common Stock 100,000 0.00 100,000
2019-11-20 ESVAL KEVIN JAMES Director A-Award A Common Stock 100,000 0.00 100,250
2019-09-13 Yampolsky Vladislav Director / 10% Owner A-Award A Common Stock 1,000,000 0.00 1,000,000
2019-09-13 Aloi Emiliano Angel Officer A-Award A Common Stock 1,000,000 0.00 1,000,000
2019-06-24 Yampolsky Vladislav Director / 10% Owner I Common Stock 0 0.00 7,635,690
2019-06-24 Schwartz Steven A Director D Common Stock 0 0.00 125,000
2019-06-06 Ceed2Med LLC 10% Owner D-Return D Common Stock 750,000 0.30 225.0K 7,635,690
2019-03-12 Johnson Andrew L. Officer D Options to purchase common stock 750,000 0.32 240.0K 0
2019-02-11 Price John C Director D Options to purchase common stock 250,000 0.20 50.0K 0
2019-02-11 GILBERT JONATHAN Director / Officer D Options to purchase common stock 1,000,000 0.01 10.0K 0
2019-01-15 Johnson Andrew L. Officer D Options to purchase common stock 31,250 0.96 30.0K 0
2019-01-11 Thompson Jeffrey M Director D Options to purchase common stock 2,000,000 0.03 50.0K 0
2019-01-11 Puzder Ken Director D Options to purchase common stock 2,000,000 0.03 50.0K 0
2019-01-11 ESVAL KEVIN JAMES Director I Series B-2 Preferred Stock 168,000 0.00 0
2019-01-09 Yampolsky Vladislav Director / 10% Owner D Option (Right to Purchase) 250,000 0.32 80.0K 0
2019-01-09 Aloi Emiliano Angel Officer D Options to purchase common stock 250,000 0.32 80.0K 0
2019-01-08 Ceed2Med LLC 0 0.00 0
2018-09-12 Ryan Timothy John Director / Officer / 10% Owner D-Return D Series D Preferred Stock (the 16 0.00 16
2018-09-04 Young Philip J Director / Officer A-Award A Stock Options (Right to Buy) 225,000 0.09 20.0K 225,000
2018-09-04 Wendt Kelley A Officer A-Award A Stock Options (Right to Buy) 225,000 0.09 20.0K 225,000
2018-09-04 Ryan Timothy John Director / Officer / 10% Owner A-Award A Stock Options (Right to Buy) 225,000 0.09 20.0K 225,000
2018-09-04 Erickson James R. Officer A-Award A Stock Options (Right to Buy) 1,000,000 0.09 89.0K 1,000,000
2018-07-05 Ryan Timothy John Director / Officer A-Award A Series D Preferred Stock (the "Series D") 16 0.00 27
2018-03-28 Young Philip J Officer A-Award A Series D Preferred Stock (the "Series D") 11 0.00 11
2018-03-28 Wendt Kelley A Officer A-Award A Series D Preferred Stock (the "Series D") 12 0.00 12
2018-03-28 Ryan Timothy John Director / Officer A-Award A Series D Preferred Stock (the "Series D") 11 0.00 11
2018-03-28 Erickson James R. Officer A-Award A Series D Preferred Stock (the "Series D") 6 0.00 6
2017-08-18 Young Philip J Director / Officer D Common Stock 0 0.00 8,520,000
2017-08-18 Wendt Kelley A Officer D Series B-1 Preferred Stock 600,000 0.00 0
2017-08-18 Ryan Timothy John Director / Officer I Common Stock 0 0.00 300,000
2017-08-18 Erickson James R. Officer D Common Stock 0 0.00 1,600,000
2017-08-18 Dimitrov Krassen Director I Common Stock 0 0.00 3,600,000

Executive team

Top executives
EBIT / Employee
-43.8K
Shares Outstanding
21.22M

Executive compensation

Executive compensation (annual)

Executive compensation not available.

CEO compensation breakdown

No CEO compensation history available.

Proxy statements

Proxy statements (DEF 14A)

No proxy statements available for this company yet.

Recent SEC filings

Recent SEC filings
Filing date Form type Filing
2025-05-09 SEC STAFF ACTION
2024-07-16 15-12G
2024-06-11 1-A
2024-05-16 8-K
2024-05-07 8-K
2024-05-06 10-Q
2024-04-01 10-K
2024-03-07 8-K
2024-02-05 8-K
2023-12-08 8-K/A

Executive team

NameTitleCompensationGender
Leslie A. Buttorff Chairman, Chief Executive Officer & Chief Financial Officer female
Nathan Joel Berman Secretary & Principal Accounting Officer male
ESG Rating
B
DRUG MANUFACTURERS - SPECIALTY & GENERIC
2024
E (Environmental)
75.8 / 66.0
Company / Sector avg.
S (Social)
68.8 / 70.0
Company / Sector avg.
G (Governance)
67.3 / 66.6
Company / Sector avg.
ESG Total
70.6 / 67.5
Company / Sector avg.
ESG Score History DRUG MANUFACTURERS - SPECIALTY & GENERIC
Benchmark vs Sector
Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend history

Earnings history

Earnings reports

Stock splits