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Inhibikase Therapeutics, Inc. (IKT)

USD2.08 +0.02 (+0.97%)
US NASDAQ Healthcare Medical - Pharmaceuticals
Address 1000 N. West Street 19801
Wilmington, DE, US
CEO Mark T. Iwicki
IPO 2020-12-23
CIK 1750149 ISIN US45719W2052

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Description

Inhibikase Therapeutics, Inc. operates as a clinical-stage pharmaceutical company that develops therapeutics to modify the course of cardiopulmonary diseases, with a primary focus on pulmonary arterial hypertension (PAH), a progressive, life-threatening disease characterized by pulmonary vascular remodeling and elevated pulmonary vascular resistance. It offers IKT-001, a novel oral prodrug of imatinib mesylate designed for the treatment of pulmonary arterial hypertension (PAH) was designed to improve areas of the molecule that might play a role in the gastrointestinal side effects associated with imatinib, while maintaining systemic exposure and efficacy through oral administration. The company has completed non-human primate safety studies and a bioequivalence clinical study in healthy volunteers, establishing dose equivalence with imatinib. IKT-001 is currently being evaluated in a global, adaptive Phase 3 clinical trial (IMPROVE-PAH), with endpoints including pulmonary vascular resistance and 6-minute walk distance. Inhibikase Therapeutics, Inc. entered into a collaborative research and development agreement with Sphaera Pharma Pte. Ltd., which was subsequently assigned to Pivot Holding LLC, for prodrug technology development and maintains an exclusive license for IKT-001. The company was founded in 2008 and is headquartered in Wilmington, Delaware.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
USD2.08 +0.02 (+0.97%)
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Volume Profile
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Liquidity & share structure
Average Volume
838.6K
Beta
0.97
Float Shares
41.65M
Free Float %
58.7%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
-5.42% -4.48% +12.94% +17.07% +18.52% -6.34% -12.33% -47.83% -94.01% -96.77% -96.77%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
vs.
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Analyst Consensus (2 ratings, all time) Hold
Price Targets & DCF
Current price
2.08
Low 4.00 +92.3%
Consensus 4.00 +92.3%
Median 4.00 +92.3%
High 4.00 +92.3%
DCF (Unlevered) 1.41 -32.4%
DCF (Levered) 1.42 -31.9%

DCF figures are point estimates: small changes in growth or discount-rate assumptions move them materially. Read them as a reference, not a precise target.

Ratings Trend (MoM) 100% Bullish
Rating 2026-05 Change
Strong Buy 1 0
Buy 6 -1
Hold 0 0
Sell 0 0
Strong Sell 0 0
Price Target Summary
Period # Analysts Avg Target
Last Month
Last Quarter
Last Year 1
4.00
+92.3%
All Time 3
5.67
+172.6%
Quality scores
Altman Z-Score
13.16
Safe zone
Piotroski F-Score
2 / 9
Weak
MOAT Score
1 / 10
No MOAT
Composite Rating
C
Overall Score
2 / 5
Medium
DCF Score
4 / 5
High
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
1 / 5
Low
P/E Score
1 / 5
Low
P/Book Score
3 / 5
Medium
Operational MOAT
✗ Below peers
  • Revenue growth Medical - Pharmaceuticals: +7.8%
  • EPS growth Medical - Pharmaceuticals: +20.2%
    +57.8% Q1'26: +33.3% (vs Q1'25)
  • FCF margin FCF growth · Medical - Pharmaceuticals: +43.3%
  • EBIT margin Medical - Pharmaceuticals: +6.8%
  • ROIC Medical - Pharmaceuticals: +6.1%
    Q1'26: +0.0% (vs Q1'25)
  • Share dilution Medical - Pharmaceuticals: +0.0%
    +41.7% Q1'26: +92.4% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Medical - Pharmaceuticals: 0.21×
    0.00× Q1'26: 0.00× (vs Q1'25)
Valuation Multiples From To
Price Forecast (3Y) From To
Model
Adjust
P/E
Theoretical Return — If Invested Today

* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.

DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (0.96) × ERP
WACC = 100% × Ke + 0% × Kd (4.1%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Intrinsic value (base): 1.41 Current price: 2.08
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2021
actual
Dec 2022
actual
Dec 2023
actual
Dec 2024
actual
Dec 2025
actual
Dec 2026
5 Rev. Ana.
3 EPS Ana.
Dec 2027
5 Rev. Ana.
3 EPS Ana.
Dec 2028
3 Rev. Ana.
3 EPS Ana.
Dec 2029
2 Rev. Ana.
1 EPS Ana.
Dec 2030
1 Rev. Ana.
1 EPS Ana.
Revenue
3.10M
est: 3.40M (-8.8%)
123.4K
est: 100.0K (+23.4%)
260.5K
est: 79.6K (+227.4%)
375.0K
362.5K – 387.5K
500.0K
500.0K – 500.0K
+33.3% YoY
36.74M
36.74M – 36.74M
+7,247.4% YoY
164.94M
164.94M – 164.94M
+349.0% YoY
290.67M
290.67M – 290.67M
+76.2% YoY
EBITDA
est: -680.0K (+100.0%)
-18.05M
est: -20.0K (-90,141.7%)
-19.91M
-27.49M
-45.89M
— – —
— – —
— – —
— – —
— – —
EBIT
-14.77M
est: -2.04M (-623.8%)
-18.05M
est: -60.0K (-29,990.3%)
-20.09M
est: -15.9K (-126,147.7%)
-27.52M
-45.95M
-75.0K
-77.5K – -72.5K
-100.0K
-100.0K – -100.0K
-33.3% YoY
-7.35M
-7.35M – -7.35M
-7,247.5% YoY
-32.99M
-32.99M – -32.99M
-349.0% YoY
-58.13M
-58.13M – -58.13M
-76.2% YoY
Net Income
-14.79M
est: -324.62M (+95.4%)
-18.05M
est: -307.97M (+94.1%)
-19.03M
est: -308.34M (+93.8%)
-27.52M
est: -62.33M (+55.9%)
-48.26M
est: -48.26M (+0.0%)
-45.70M
-54.24M – -37.17M
+5.3% YoY
-46.71M
-56.82M – -36.59M
-2.2% YoY
-36.11M
-44.67M – -27.56M
+22.7% YoY
11.31M
11.31M – 11.31M
+131.3% YoY
59.48M
59.48M – 59.48M
+426.1% YoY
SGA
est: 52.46M (-100.0%)
6.21M
est: 1.54M (+302.5%)
6.73M
est: 1.24M (+441.3%)
11.38M
23.56M
5.86M
5.67M – 6.06M
7.82M
7.82M – 7.82M
+33.3% YoY
574.22M
574.22M – 574.22M
+7,247.4% YoY
2.58B
2.58B – 2.58B
+349.0% YoY
4.54B
4.54B – 4.54B
+76.2% YoY
EPS
-4.88
est: -4.68 (-4.3%)
-4.26
est: -4.44 (+4.1%)
-3.57
est: -3.14 (-13.8%)
-1.16
est: -0.90 (-28.4%)
-0.49
est: -0.50 (+1.9%)
-0.47
-0.55 – -0.38
+5.9% YoY
-0.48
-0.58 – -0.37
-2.1% YoY
-0.39
-0.45 – -0.28
+19.4% YoY
0.12
0.12 – 0.12
+129.7% YoY
0.61
0.61 – 0.61
+426.1% YoY
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-12 C 2/5 4/5 1/5 1/5 1/5 1/5 3/5
2026-05-11 C 2/5 3/5 1/5 1/5 1/5 1/5 4/5
2026-05-08 C 2/5 3/5 1/5 1/5 1/5 1/5 4/5
2026-05-07 C 2/5 3/5 1/5 1/5 1/5 1/5 4/5
2026-05-06 C 2/5 3/5 1/5 1/5 1/5 1/5 4/5
2026-05-05 C 2/5 3/5 1/5 1/5 1/5 1/5 4/5
2026-05-04 C 2/5 3/5 1/5 1/5 1/5 1/5 4/5
2026-05-01 C 2/5 3/5 1/5 1/5 1/5 1/5 4/5
2026-04-30 C 2/5 3/5 1/5 1/5 1/5 1/5 4/5
2026-04-29 C 2/5 3/5 1/5 1/5 1/5 1/5 4/5
2026-04-28 C 2/5 3/5 1/5 1/5 1/5 1/5 4/5
2026-04-27 C+ 2/5 4/5 1/5 1/5 1/5 1/5 4/5
2026-04-24 C+ 2/5 4/5 1/5 1/5 1/5 1/5 4/5
2026-04-23 C+ 2/5 4/5 1/5 1/5 1/5 1/5 4/5
2026-04-22 C+ 2/5 4/5 1/5 1/5 1/5 1/5 4/5
2026-04-21 C+ 2/5 4/5 1/5 1/5 1/5 1/5 4/5
2026-04-20 C+ 2/5 4/5 1/5 1/5 1/5 1/5 4/5
2026-04-17 C+ 2/5 4/5 1/5 1/5 1/5 1/5 4/5
2026-04-16 C+ 2/5 4/5 1/5 1/5 1/5 1/5 4/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
-35.74M
OE per share TTM
-0.33
Owner's Yield
-10.80%
Maintenance CapEx ratio
Maint CapEx / Avg PPE
19.0%

Ownership Overview

Ownership breakdown
At a glance
Institutional holders
28
Total invested
33.73M
Insider transactions (90d)
0
Beneficial owners (>5%)
26
Beneficial owners (>5%)
# Reporting person Amount owned % of class Sole voting Shared voting Sole dispositive Shared dispositive Type Citizenship Filing date SEC filing
1 Frank M. Sands 10.95M 16.30% 10.95M IN Cayman Islands 2024-10-25
2 Sands Capital Life Sciences Pulse Fund II, L.P. 10.95M 16.30% 10.95M 10.95M PN Cayman Islands 2024-10-25
3 Sands Capital Ventures, LLC 10.95M 16.30% 10.95M 10.95M OO Cayman Islands 2024-10-25
4 Soleus PE GP III, LLC 7.23M 9.99% 7.23M 7.23M OO Delaware 2024-10-28
5 Soleus Private Equity Fund III, L.P. 7.23M 9.99% 7.23M 7.23M PN Delaware 2024-10-28
6 Soleus Private Equity GP III, LLC 7.23M 9.99% 7.23M 7.23M OO Delaware 2024-10-28
7 Soleus Capital Group, LLC 6.98M 9.99% 6.98M 6.98M OO Delaware 2024-10-28
8 Soleus Capital Master Fund, L.P. 6.98M 9.99% 6.98M 6.98M FI Delaware 2024-10-28
9 Soleus Capital, LLC 6.98M 9.99% 6.98M 6.98M OO Delaware 2024-10-28
10 Capital LP 6.81M 9.99% 6.81M 6.81M IA Delaware, USA 2024-10-17
11 Capital Master LP 6.81M 9.99% 6.81M 6.81M OO Delaware, USA 2024-10-17
12 Joseph Edelman 6.80M 9.99% 6.80M 6.80M IN Delaware 2024-10-22
13 Perceptive Advisors LLC 6.80M 9.99% 6.80M 6.80M IA Delaware 2024-10-22
14 Perceptive Life Sciences Master Fund, Ltd. 6.80M 9.99% 6.80M 6.80M CO Delaware 2024-10-22
15 Guy Levy 6.76M 9.99% 6.76M 6.76M IN Delaware 2024-10-28
16 Soleus Capital Management, L.P. 6.76M 9.99% 6.76M 6.76M PN Delaware 2024-10-28
17 Fairmount Funds Management LLC 6.62M 9.90% 6.62M IA Delaware 2024-10-17
18 Fairmount Healthcare Fund II L.P. 6.62M 9.90% 6.62M PN Delaware 2024-10-17
19 Peter Harwin 6.62M 9.90% 6.62M HC, IN Delaware 2024-10-17
20 Tomas Kiselak 6.62M 9.90% 6.62M HC, IN Delaware 2024-10-17
21 Holdings LLC 5.84M 8.69% 5.84M 5.84M OO DELAWARE 2024-10-28
22 LLC 5.84M 8.69% 5.84M 5.84M OO DELAWARE 2024-10-28
23 Armistice Capital, LLC 758.9K 9.99% 758.9K IA, OO Delaware 2024-11-14
24 Steven Boyd 758.9K 9.99% 758.9K HC, IN Delaware 2024-11-14
25 Point72 Asset Management, L.P. 625.0K 8.40% 625.0K PN Delaware 2024-10-10
26 Steven A. Cohen 625.0K 8.40% 625.0K IN Delaware 2024-10-10

Institutional Activity (13F)

Institutional ownership trend From To
13F snapshot — 2026 Q1
Investors holding
28
-45 vs prev Q
New positions
14
Closed positions
59
Increased
22
Reduced
2
Put/Call ratio
0.00
Calls held
Puts held
Top institutional holders
# Investor Shares / Δ Mkt value / Δ Own% / Δ Weight% / Δ Avg px / Perf. Hold / Status
1 SANDS CAPITAL VENTURES, LLC 13.02M +2.1M (+18.9%) 26.69M +8.9M (+50.5%) 14.46% +2.292 pp 5.15% +1.261 pp USD3.06 -33.0% 5 qtrs
2 SOLEUS CAPITAL MANAGEMENT, L.P. 10.88M +4.6M (+71.9%) 22.29M +12.0M (+117.6%) 12.08% +5.050 pp 0.82% +0.307 pp USD2.75 -25.5% 5 qtrs
3 FAIRMOUNT FUNDS MANAGEMENT LLC 8.63M +2.5M (+40.8%) 17.68M +7.8M (+78.2%) 9.58% +2.773 pp 1.35% +0.453 pp USD2.90 -29.3% 5 qtrs
4 ADAR1 CAPITAL MANAGEMENT, LLC 8.06M +2.8M (+53.7%) 16.53M +8.0M (+94.5%) 8.95% +3.125 pp 1.21% +0.416 pp USD2.80 -26.8% 5 qtrs
5 BLACKSTONE INC. 5.94M +3.3M (+125.1%) 12.17M +7.9M (+184.8%) 6.59% +3.663 pp 0.05% +0.031 pp USD2.46 -16.7% 5 qtrs
6 SIREN, L.L.C. 5.85M +5.9M (+100.0%) 11.99M +12.0M (+100.0%) 6.50% +6.496 pp 0.36% +0.358 pp USD2.05 +0.0% 1 qtrs NEW
7 PERCEPTIVE ADVISORS LLC 5.42M +— (+0.0%) 11.11M +2.3M (+26.5%) 6.02% -0.003 pp 0.20% -0.056 pp USD3.25 -36.9% 5 qtrs
8 COMMODORE CAPITAL LP 5.40M +— (+0.0%) 11.06M +2.3M (+26.5%) 5.99% -0.003 pp 0.74% +0.310 pp USD3.24 -36.7% 5 qtrs
9 VANGUARD GROUP INC 4.56M +1.3M (+39.3%) 9.35M +4.0M (+76.2%) 5.06% +1.426 pp 0.00% +0.000 pp USD2.78 -26.3% 11 qtrs
10 NANTAHALA CAPITAL MANAGEMENT, LLC 3.93M +1.7M (+79.4%) 8.06M +4.5M (+127.0%) 4.36% +1.930 pp 0.27% +0.143 pp USD2.72 -24.6% 5 qtrs
11 SATURN V CAPITAL MANAGEMENT LLC 3.86M +3.9M (+100.0%) 7.91M +7.9M (+100.0%) 4.28% +4.283 pp 1.45% +1.451 pp USD2.05 +0.0% 1 qtrs NEW
12 BLACKROCK, INC. 3.31M +230.4K (+7.5%) 6.78M +1.8M (+36.0%) 3.67% +0.254 pp 0.00% +0.000 pp USD2.06 -0.5% 5 qtrs
13 STONEPINE CAPITAL MANAGEMENT, LLC 2.35M +1.6M (+219.5%) 4.81M +3.6M (+304.3%) 2.61% +1.791 pp 3.51% +2.546 pp USD2.42 -15.3% 5 qtrs
14 INTEGRAL HEALTH ASSET MANAGEMENT, LLC 1.75M +1.8M (+100.0%) 3.59M +3.6M (+100.0%) 1.94% +1.943 pp 0.18% +0.178 pp USD2.05 +0.0% 1 qtrs NEW
15 AMERIPRISE FINANCIAL INC 1.38M +1.4M (+100.0%) 2.82M +2.8M (+100.0%) 1.53% +1.529 pp 0.00% +0.001 pp USD2.05 +0.0% 1 qtrs NEW
16 CITADEL ADVISORS LLC 1.24M +1.2M (+1,635.2%) 2.55M +2.4M (+2,095.8%) 1.38% +1.301 pp 0.00% +0.000 pp USD2.03 +1.0% 2 qtrs
17 GEODE CAPITAL MANAGEMENT, LLC 1.13M +15.7K (+1.4%) 2.31M +510.5K (+28.3%) 1.25% +0.017 pp 0.00% +0.000 pp USD2.23 -8.1% 11 qtrs
18 EXOME ASSET MANAGEMENT LLC 600.0K +600.0K (+100.0%) 1.23M +1.2M (+100.0%) 0.67% +0.666 pp 0.59% +0.588 pp USD2.05 +0.0% 1 qtrs NEW
19 STATE STREET CORP 554.8K +47.1K (+9.3%) 1.14M +314.9K (+38.3%) 0.62% +0.052 pp 0.00% +0.000 pp USD1.96 +4.6% 11 qtrs
20 533.6K +533.6K (+100.0%) 1.09M +1.1M (+100.0%) 0.59% +0.593 pp 0.83% +0.832 pp USD2.05 +0.0% 1 qtrs NEW
21 NORTHERN TRUST CORP 322.7K -51.6K (-13.8%) 661.6K +55.2K (+9.1%) 0.36% -0.058 pp 0.00% +0.000 pp USD2.16 -5.1% 5 qtrs
22 MILLENNIUM MANAGEMENT LLC 169.9K +169.9K (+100.0%) 348.2K +348.2K (+100.0%) 0.19% +0.189 pp 0.00% +0.000 pp USD2.05 +0.0% 1 qtrs NEW
23 BLAIR WILLIAM & CO/IL 153.0K +— (+0.0%) 313.6K +65.8K (+26.5%) 0.17% 0.000 pp 0.00% +0.000 pp USD1.78 +15.2% 11 qtrs
24 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 152.3K +— (+0.0%) 312.2K +65.5K (+26.5%) 0.17% 0.000 pp 0.00% +0.000 pp USD1.95 +5.1% 3 qtrs
25 BANK OF NEW YORK MELLON CORP 137.5K -1.2K (-0.9%) 281.8K +57.2K (+25.5%) 0.15% -0.001 pp 0.00% +0.000 pp USD1.94 +5.7% 3 qtrs
26 JANE STREET GROUP, LLC 116.0K +116.0K (+100.0%) 237.8K +237.8K (+100.0%) 0.13% +0.129 pp 0.00% +0.000 pp USD2.05 +0.0% 1 qtrs NEW
27 BARCLAYS PLC 94.8K +9.2K (+10.8%) 194.3K +55.7K (+40.2%) 0.11% +0.010 pp 0.00% +0.000 pp USD2.85 -28.1% 5 qtrs
28 UBS GROUP AG 94.5K -41.7K (-30.6%) 193.8K -27.0K (-12.2%) 0.11% -0.046 pp 0.00% +0.000 pp USD1.91 +7.3% 10 qtrs
29 PERSISTENT ASSET PARTNERS LTD 93.4K +93.4K (+100.0%) 191.5K +191.5K (+100.0%) 0.10% +0.104 pp 0.09% +0.086 pp USD2.05 +0.0% 1 qtrs NEW
30 GOLDMAN SACHS GROUP INC 85.3K +74.5K (+694.3%) 174.8K +157.4K (+905.1%) 0.09% +0.083 pp 0.00% +0.000 pp USD2.00 +2.5% 5 qtrs
31 MORGAN STANLEY 79.7K +23.7K (+42.2%) 163.3K +72.6K (+80.0%) 0.09% +0.026 pp 0.00% +0.000 pp USD2.05 +0.0% 11 qtrs
32 NUVEEN, LLC 78.7K +— (+0.0%) 161.3K +33.8K (+26.5%) 0.09% +0.000 pp 0.00% +0.000 pp USD1.95 +5.1% 3 qtrs
33 WELLS FARGO & COMPANY/MN 67.8K +22.1K (+48.3%) 139.1K +64.9K (+87.6%) 0.08% +0.025 pp 0.00% +0.000 pp USD1.95 +5.1% 11 qtrs
34 FMR LLC 57.4K -48.4K (-45.8%) 117.6K -53.7K (-31.4%) 0.06% -0.054 pp 0.00% +0.000 pp USD1.95 +5.1% 3 qtrs
35 DEUTSCHE BANK AG\ 54.9K -25.6K (-31.8%) 112.6K -17.8K (-13.7%) 0.06% -0.029 pp 0.00% +0.000 pp USD1.62 +26.5% 2 qtrs
36 NEW YORK STATE COMMON RETIREMENT FUND 47.9K +— (+0.0%) 98.2K +20.6K (+26.5%) 0.05% +0.000 pp 0.00% +0.000 pp USD1.95 +5.1% 3 qtrs
37 RHUMBLINE ADVISERS 47.2K -10.4K (-18.1%) 96.7K +3.5K (+3.7%) 0.05% -0.012 pp 0.00% +0.000 pp USD1.95 +5.1% 3 qtrs
38 BANK OF AMERICA CORP /DE/ 46.4K +29.3K (+171.4%) 95.1K +67.4K (+243.4%) 0.05% +0.033 pp 0.00% +0.000 pp USD2.14 -4.2% 9 qtrs
39 INVESCO LTD. 32.3K -772.0 (-2.3%) 66.1K +12.6K (+23.6%) 0.04% -0.001 pp 0.00% +0.000 pp USD1.93 +6.2% 3 qtrs
40 PRICE T ROWE ASSOCIATES INC /MD/ 30.6K +— (+0.0%) 63.0K +13.0K (+26.0%) 0.03% +0.000 pp 0.00% +0.000 pp USD1.95 +5.1% 3 qtrs
41 MIRAE ASSET GLOBAL ETFS HOLDINGS LTD. 28.9K +912.0 (+3.3%) 59.2K +13.9K (+30.7%) 0.03% +0.001 pp 0.00% +0.000 pp USD1.95 +5.1% 3 qtrs
42 CAXTON CORP 28.5K +12.1K (+73.6%) 58.3K +31.8K (+119.6%) 0.03% +0.013 pp 1.36% +1.247 pp USD2.74 -25.2% 5 qtrs
43 INTECH INVESTMENT MANAGEMENT LLC 26.9K -5.0K (-15.8%) 55.1K +3.4K (+6.6%) 0.03% -0.006 pp 0.00% +0.000 pp USD1.94 +5.7% 3 qtrs
44 JPMORGAN CHASE & CO 24.8K -25.1K (-50.2%) 50.9K -30.0K (-37.0%) 0.03% -0.028 pp 0.00% +0.000 pp USD1.81 +13.3% 3 qtrs
45 VIRTU FINANCIAL LLC 22.9K +9.4K (+70.1%) 47.0K +25.0K (+113.6%) 0.03% +0.011 pp 0.00% +0.001 pp USD1.80 +13.9% 2 qtrs
46 SUSQUEHANNA INTERNATIONAL GROUP, LLP 21.5K -24.1K (-52.8%) 44.1K -29.7K (-40.3%) 0.02% -0.027 pp 0.00% +0.000 pp USD2.19 -6.4% 4 qtrs
47 XTX TOPCO LTD 20.3K +20.3K (+100.0%) 41.6K +41.6K (+100.0%) 0.02% +0.023 pp 0.00% +0.001 pp USD2.05 +0.0% 1 qtrs NEW
48 POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY 17.6K +— (+0.0%) 36.2K +7.6K (+26.5%) 0.02% +0.000 pp 0.00% +0.000 pp USD1.95 +5.1% 3 qtrs
49 SCIENTECH RESEARCH LLC 16.0K +16.0K (+100.0%) 32.8K +32.8K (+100.0%) 0.02% +0.018 pp 0.02% +0.021 pp USD2.05 +0.0% 1 qtrs NEW
50 VOYA INVESTMENT MANAGEMENT LLC 13.1K +— (+0.0%) 26.9K +5.7K (+26.5%) 0.01% +0.000 pp 0.00% +0.000 pp USD1.95 +5.1% 3 qtrs
51 BNP PARIBAS ARBITRAGE, SNC 12.9K -2.7K (-17.6%) 26.4K +1.1K (+4.3%) 0.01% -0.003 pp 0.00% +0.000 pp USD1.81 +13.3% 3 qtrs
52 SANCTUARY ADVISORS, LLC 12.5K +12.5K (+100.0%) 25.7K +25.7K (+100.0%) 0.01% +0.014 pp 0.00% +0.000 pp USD2.05 +0.0% 1 qtrs NEW
53 VICTORY CAPITAL MANAGEMENT INC 11.4K +11.4K (+100.0%) 23.4K +23.4K (+100.0%) 0.01% +0.013 pp 0.00% +0.000 pp USD2.05 +0.0% 1 qtrs NEW
54 PROSHARE ADVISORS LLC 11.0K +705.0 (+6.8%) 22.6K +5.9K (+35.2%) 0.01% +0.001 pp 0.00% +0.000 pp USD1.96 +4.6% 3 qtrs
55 RUSSELL INVESTMENTS GROUP, LTD. 10.8K +3.1K (+40.4%) 22.2K +9.7K (+77.7%) 0.01% +0.004 pp 0.00% +0.000 pp USD1.74 +17.8% 2 qtrs
56 BUCKINGHAM STRATEGIC PARTNERS 10.7K +11.0 (+0.1%) 22.0K +4.6K (+26.7%) 0.01% +0.000 pp 0.00% +0.000 pp USD1.95 +5.1% 3 qtrs
57 HRT FINANCIAL LP 10.6K +10.6K (+100.0%) 21.0K +21.0K (+100.0%) 0.01% +0.012 pp 0.00% +0.000 pp USD2.05 +0.0% 1 qtrs NEW
58 ROYAL BANK OF CANADA 6.7K +6.0K (+903.5%) 14.0K +13.0K (+1,300.0%) 0.01% +0.007 pp 0.00% +0.000 pp USD2.04 +0.5% 3 qtrs
59 TOWER RESEARCH CAPITAL LLC (TRC) 6.5K -537.0 (-7.6%) 13.3K +1.9K (+16.9%) 0.01% -0.001 pp 0.00% +0.000 pp USD1.62 +26.5% 3 qtrs
60 AMERITAS INVESTMENT PARTNERS, INC. 6.2K +— (+0.0%) 12.7K +2.7K (+26.5%) 0.01% +0.000 pp 0.00% +0.000 pp USD1.95 +5.1% 3 qtrs
61 LEGAL & GENERAL GROUP PLC 5.5K +— (+0.0%) 11.3K +2.4K (+26.9%) 0.01% +0.000 pp 0.00% +0.000 pp USD1.95 +5.1% 3 qtrs
62 PINNACLE WEALTH PLANNING SERVICES, INC. 5.4K +5.4K (+100.0%) 11.1K +11.1K (+100.0%) 0.01% +0.006 pp 0.00% +0.001 pp USD2.05 +0.0% 1 qtrs NEW
63 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 3.7K -61.0 (-1.6%) 7.6K +1.5K (+24.5%) 0.00% 0.000 pp 0.00% +0.000 pp USD1.95 +5.1% 3 qtrs
64 CITIGROUP INC 3.3K +2.4K (+264.3%) 6.7K +5.3K (+361.1%) 0.00% +0.003 pp 0.00% +0.000 pp USD2.38 -13.9% 5 qtrs
65 STERLING CAPITAL MANAGEMENT LLC 3.2K -607.0 (-15.9%) 6.6K +401.0 (+6.5%) 0.00% -0.001 pp 0.00% +0.000 pp USD1.75 +17.1% 3 qtrs
66 AMALGAMATED BANK 1.9K -165.0 (-8.0%) 4.0K +1.0K (+33.3%) 0.00% 0.000 pp 0.00% +0.000 pp USD1.95 +5.1% 3 qtrs
67 PNC FINANCIAL SERVICES GROUP, INC. 101.00 +11.0 (+12.2%) 207.00 +61.0 (+41.8%) 0.00% +0.000 pp 0.00% +0.000 pp USD1.65 +24.2% 2 qtrs
68 EVERSOURCE WEALTH ADVISORS, LLC 4.00 +4.0 (+100.0%) 8.00 +8.0 (+100.0%) 0.00% +0.000 pp 0.00% +0.000 pp USD2.00 +2.5% 1 qtrs NEW
69 ALLWORTH FINANCIAL LP 1.00 +1.0 (+100.0%) 3.00 +3.0 (+100.0%) 0.00% +0.000 pp 0.00% +0.000 pp USD2.00 +2.5% 1 qtrs NEW
70 SRS CAPITAL ADVISORS, INC. -86.0 (-100.0%) -139.0 (-100.0%) 0.00% 0.000 pp 0.00% +0.000 pp USD 2 qtrs SOLD
Ownership breakdown by holder

ETF Ownership

Top ETFs holding this stock Held by 40 ETFs in our universe
# ETF Weight Est. AUM exposure TER
1 ALPS Medical Breakthroughs ETF SBIO 0.14% 294.1K 0.50%
2 iShares Micro-Cap ETF IWC 0.06% 829.7K 0.60%
3 iShares Russell 2000 Value ETF IWN 0.02% 2.23M 0.24%
4 Vanguard Russell 2000 Value ETF VTWV 0.01% 130.0K 0.06%
5 Xtrackers Russell 2000 UCITS ETF 1C XRSU.L 0.01% 227.5K 0.30%
6 Global X - Russell 2000 ETF RSSL 0.01% 115.8K 0.08%
7 Invesco Russell 2000 UCITS ETF RTYS.L 0.01% 25.1K 0.25%
8 iShares Russell 2000 BuyWrite ETF IWMW 0.01% 4.3K 0.39%
9 iShares Russell 2000 ETF IWM 0.01% 6.26M 0.19%
10 iShares U.S. Small Cap Index ETF (CAD-Hedged) XSU.TO 0.01% 40.8K 0.36%

Insider Activity

Insider Activity — Latest Quarter
Ratio by transactions
0.00
Bearish
Buys
3
Sells
0
Shares acquired
6.87M
Shares disposed
Cash buys
Cash sales
Net activity
+6,869,142
Insider buys vs sells (history) From To
Recent insider transactions From To
Date Person Role Transaction A/D Security Shares Price Value Owned after D/I Filing
2026-02-21 Munshi Amit Director D-Return D Common Stock 19,089 0.00 38,176 D
2026-02-21 Cabell Christopher Officer D-Return D Common Stock 338,282 0.00 676,564 D
2026-02-21 Aurentz Vincent Director D-Return D Common Stock 255,299 0.00 510,596 D
2026-01-05 McIntyre David Officer A-Award A Stock Option (Right to Buy) 986,319 2.01 1.98M 986,319 D
2026-01-05 Iwicki Mark T Director / Officer A-Award A Stock Option (Right to Buy) 4,982,706 2.01 10.02M 4,982,706 D
2026-01-05 Cabell Christopher Officer A-Award A Stock Option (Right to Buy) 900,117 2.01 1.81M 900,117 D
2025-11-21 Sands Capital Life Sciences Pulse Fund II, L.P. 10% Owner P-Purchase A Common Stock 2,068,965 1.45 3.00M 13,018,965 D
2025-06-30 Munshi Amit Director A-Award A Stock Option (Right to Buy) 108,176 1.95 210.9K 108,176 D
2025-06-30 Kush Arvind Director A-Award A Stock Option (Right to Buy) 108,176 1.95 210.9K 108,176 D
2025-06-30 Canner David Director A-Award A Stock Option (Right to Buy) 108,176 1.95 210.9K 108,176 D
2025-06-30 Bellini Roberto Director A-Award A Stock Option (Right to Buy) 108,176 1.95 210.9K 108,176 D
2025-06-30 BERMAN DENNIS N Director A-Award A Stock Option (Right to Buy) 108,176 1.95 210.9K 108,176 D
2025-06-30 Aurentz Vincent Director A-Award A Stock Option (Right to Buy) 108,176 1.95 210.9K 108,176 D
2025-06-06 Sands Capital Life Sciences Pulse Fund II, L.P. 10% Owner Common Stock 0 0.00 10,950,000 D
2025-04-14 McIntyre David Officer Common Stock 0 0.00 10,285 D
2025-02-21 Munshi Amit Director A-Award A Common Stock 57,265 0.00 57,265 D
2025-02-21 Iwicki Mark T Director / Officer A-Award A Stock Option (Right to Buy) 602,346 2.23 1.34M 602,346 D
2025-02-21 Cabell Christopher Officer A-Award A Stock Option (Right to Buy) 1,100,705 2.23 2.45M 1,100,705 D
2025-02-21 Aurentz Vincent Director A-Award A Stock Option (Right to Buy) 134,427 2.23 299.8K 134,427 D
2025-02-17 Iwicki Mark T Director / Officer A-Award A Stock Option (Right to Buy) 1,794,291 2.35 4.22M 1,794,291 D
2025-02-14 Munshi Amit Director A-Award A Stock Option (Right to Buy) 56,600 2.35 133.0K 56,600 D
2025-02-14 Kush Arvind Director A-Award A Stock Option (Right to Buy) 56,600 2.35 133.0K 56,600 D
2025-02-14 Iwicki Mark T Director / Officer A-Award A Stock Option (Right to Buy) 4,373,857 2.35 10.28M 4,373,857 D
2025-02-14 Freeman Roy Lester Director A-Award A Stock Option (Right to Buy) 22,640 2.35 53.2K 22,640 D
2025-02-14 Canner David Director A-Award A Stock Option (Right to Buy) 22,640 2.35 53.2K 22,640 D
2025-02-14 Bellini Roberto Director A-Award A Stock Option (Right to Buy) 73,580 2.35 172.9K 73,580 D
2025-02-14 BERMAN DENNIS N Director A-Award A Stock Option (Right to Buy) 39,620 2.35 93.1K 39,620 D
2025-01-21 Werner Milton H. Director / Officer A-Award A Stock Option (Right to Buy) 3,643 1.26 4.6K 3,643 D
2025-01-21 Lees-Rolfe Garth Officer A-Award A Stock Option (Right to Buy) 5,834 1.26 7.4K 5,834 D
2025-01-21 Freeman Roy Lester Director A-Award A Stock Option (Right to Buy) 1,138 1.26 1.4K 1,138 D
2025-01-21 BERMAN DENNIS N Director D-Return D Stock Option (Right to Buy) 6,667 3.61 24.1K 0 I
2025-01-03 Werner Milton H. Director / Officer A-Award A Stock Option (Right to Buy) 5,315,056 1.26 6.70M 5,315,056 D
2025-01-03 Lees-Rolfe Garth Officer A-Award A Stock Option (Right to Buy) 470,861 1.26 593.3K 470,861 D
2025-01-03 Freeman Roy Lester Director A-Award A Stock Option (Right to Buy) 344,452 1.26 434.0K 344,452 D
2025-01-03 BERMAN DENNIS N Director A-Award A Stock Option (Right to Buy) 344,452 1.26 434.0K 344,452 D
2024-10-21 Sands Capital Life Sciences Pulse Fund II, L.P. 10% Owner Common Stock 0 0.00 10,950,000 D
2024-10-21 Munshi Amit Director P-Purchase A Common Stock 365,000 1.37 500.1K 365,000 I
2024-10-21 Kush Arvind 0 0.00 0
2024-10-21 Canner David 0 0.00 0
2024-10-21 Bellini Roberto 0 0.00 0
2024-07-16 GRINT PAUL C Director A-Award A Stock Option (right to buy) 30,000 1.54 46.2K 30,000
2024-07-16 Freeman Roy Lester Director A-Award A Stock Option (right to buy) 30,000 1.54 46.2K 30,000
2024-07-16 Dion Gisele Director A-Award A Stock Option (right to buy) 30,000 1.54 46.2K 30,000
2024-07-16 BERMAN DENNIS N Director A-Award A Stock Option (right to buy) 30,000 1.54 46.2K 30,000
2024-04-01 Werner Milton H. Director / Officer / 10% Owner A-Award A Stock Option (right to buy) 45,000 2.16 97.2K 45,000
2024-04-01 Lees-Rolfe Garth Officer A-Award A Stock Option (right to buy) 90,000 2.16 194.4K 90,000
2023-06-30 GRINT PAUL C Director A-Award A Stock Option (right to buy) 6,667 3.61 24.1K 6,667
2023-06-30 Freeman Roy Lester Director A-Award A Stock Option (right to buy) 6,667 3.61 24.1K 6,667
2023-06-30 Dion Gisele Director A-Award A Stock Option (right to buy) 6,667 3.61 24.1K 6,667
2023-06-30 BERMAN DENNIS N Director A-Award A Stock Option (right to buy) 6,667 3.61 24.1K 6,667
2023-03-01 Werner Milton H. Director / Officer / 10% Owner A-Award A Stock Option (right to buy) 210,000 0.74 155.4K 210,000
2023-03-01 FRATTAROLI JOSEPH Officer A-Award A Stock Option (right to buy) 90,000 0.74 66.6K 90,000
2022-09-01 Dion Gisele Director A-Award A Stock Option (right to buy) 60,000 0.00 60,000
2022-08-16 Werner Milton H. Officer P-Purchase A Common Stock 5,000 0.80 4.0K 5,335,433
2022-06-24 O'Farrell Elizabeth G. Director A-Award A Stock Option (right to buy) 40,000 0.00 40,000
2022-06-24 GRINT PAUL C Director A-Award A Stock Option (right to buy) 40,000 0.81 32.4K 40,000
2022-06-24 Freeman Roy Lester Director A-Award A Stock Option (right to buy) 40,000 0.00 40,000
2022-06-24 BERMAN DENNIS N Director A-Award A Stock Option (right to buy) 40,000 0.00 40,000
2022-05-27 Werner Milton H. Officer P-Purchase A Common Stock 5,000 0.98 4.9K 5,330,433
2022-05-20 Werner Milton H. Officer P-Purchase A Common Stock 10,000 0.60 6.0K 5,325,433
2022-05-19 FRATTAROLI JOSEPH Officer P-Purchase A Common Stock 3,948 0.64 2.5K 48,091
2022-03-07 Werner Milton H. Officer A-Award A Stock Option (right to buy) 125,000 0.00 125,000
2022-03-07 FRATTAROLI JOSEPH Officer A-Award A Stock Option (right to buy) 62,500 0.00 62,500
2022-01-03 Werner Milton H. Director / Officer / 10% Owner M-Exempt A Common Stock 21,853 2.02 44.1K 5,315,433
2021-11-17 Werner Milton H. Director / Officer / 10% Owner P-Purchase A Common Stock 1,334 1.94 2.6K 23,589
2021-08-25 FRATTAROLI JOSEPH Officer I Warrant (right to buy) 150,000 5.90 885.0K 0
2021-08-17 Werner Milton H. Director / Officer / 10% Owner M-Exempt A Common Stock 21,853 2.02 44.1K 5,293,580
2021-06-25 O'Farrell Elizabeth G. Director A-Award A Stock Option (right to buy) 22,677 2.92 66.2K 22,677
2021-06-25 GRINT PAUL C Director A-Award A Stock Option (right to buy) 22,677 2.92 66.2K 22,677
2021-06-25 Freeman Roy Lester Director A-Award A Stock Option (right to buy) 22,677 2.92 66.2K 22,677
2021-06-25 BERMAN DENNIS N Director A-Award A Stock Option (right to buy) 22,677 2.92 66.2K 22,677
2021-05-14 Werner Milton H. Director / Officer / 10% Owner M-Exempt A Common Stock 43,707 0.38 16.6K 5,288,645
2020-12-28 FRATTAROLI JOSEPH Officer C-Conversion D Convertible Note 0 10.00 0
2020-12-22 Werner Milton H. Director / Officer / 10% Owner D Common Stock 0 0.00 5,244,938
2020-12-22 O'Farrell Elizabeth G. Director D Stock Option (right to buy) 43,707 5.57 243.4K 0
2020-12-22 GRINT PAUL C Director D Stock Option (right to buy) 43,707 5.57 243.4K 0
2020-12-22 Freeman Roy Lester Director D Stock Option (right to buy) 43,707 5.57 243.4K 0
2020-12-22 FRATTAROLI JOSEPH Officer I Convertible Note 0 0.00 0
2020-12-22 BERMAN DENNIS N Director I Stock Option (right to buy) 43,707 5.57 243.4K 0
2011-06-15 Kalman Daniel 10% Owner D Stock Option (right to buy) 1,748,312 0.38 664.4K 0
2011-06-01 Werner Milton H. Director / Officer / 10% Owner D Stock Option (right to buy) 43,707 0.38 16.6K 0

Executive team

Top executives
Shares Outstanding
71.00M

Executive compensation

Executive compensation (annual)
# Year Executive Salary Bonus Stock award Option award Incentive Other Total % Stock-
based
Filing
1 2025 Mark Iwicki Chief Executive Officer and Director 624.2K 29.43M 532.5K 30.59M 96.22%
2 2025 Chris Cabell, M.D. President and Head of Research and Development 429.2K 6.76M 281.3K 7.48M 90.50%
3 2025 David McIntyre Chief Financial Officer 347.2K 4.90M 272.8K 5.52M 88.77%
4 2025 Milton H. Werner, Ph.D. Former President and Chief Executive Officer 729.0K 40.4K 31.5K 2.1K 803.1K 5.04%
5 2024 Milton H. Werner, Ph.D. Former President and Chief Executive Officer 523.0K 7.17M 267.8K 15.8K 7.98M 89.89%
6 2024 Garth Lees-Rolfe Former Chief Financial Officer 307.0K 799.7K 103.5K 1.21M 66.08%
7 2024 Joseph Frattaroli, CPA Former Chief Financial Officer 354.9K 15.5K 370.4K 4.19%
8 2023 Milton H. Werner, Ph.D. Former President and Chief Executive Officer 510.0K 113.5K 170.9K 17.1K 811.4K 13.98%
9 2023 Milton H. Werner, Ph.D. President and Chief Executive Officer 510.0K 113.5K 170.9K 17.1K 811.4K 13.98%
10 2023 Joseph Frattaroli, C.P.A. Former Chief Financial Officer 408.3K 48.6K 123.0K 580.0K 8.39%
11 2023 Joseph Frattaroli, CPA Former Chief Financial Officer 408.3K 48.6K 123.0K 580.0K 8.39%
12 2022 Milton H. Werner, Ph.D. President and Chief Executive Officer 500.8K 85.9K 140.3K 17.1K 744.1K 11.54%
13 2022 Joseph Frattaroli, C.P.A. Former Chief Financial Officer 395.8K 42.9K 136.0K 574.8K 7.47%
14 2022 Joseph Frattaroli, C.P.A. Chief Financial Officer 395.8K 42.9K 136.0K 574.8K 7.47%
15 2021 Milton H. Werner, Ph.D. President and Chief Executive Officer 455.0K 138.5K 17.1K 610.7K 0.00%
16 2021 Joseph Frattaroli, C.P.A. Chief Financial Officer 375.0K 112.5K 487.5K 0.00%
17 2020 Joseph Frattaroli, C.P.A. Chief Financial Officer 300.0K 1.34M 1.64M 81.73%
18 2020 Milton H. Werner, Ph.D. President and Chief Executive Officer 292.8K 653.4K 14.5K 960.7K 68.01%
19 2019 Milton H. Werner, Ph.D. President and Chief Executive Officer 292.8K 77.3K 14.5K 384.6K 20.09%
20 2019 Joseph Frattaroli, C.P.A. Chief Financial Officer 300.0K 300.0K 0.00%
CEO compensation breakdown

Proxy statements

Proxy statements (DEF 14A)
Filing date Form type Filing
2026-04-30 DEFA14A
2026-04-30 DEF 14A
2026-04-20 PRE 14A
2025-06-12 DEFA14A
2025-05-12 DEFA14A
2025-05-12 DEF 14A
2025-05-02 PRE 14A

Recent SEC filings

Recent SEC filings
Filing date Form type Filing
2026-05-12 8-K
2026-05-12 10-Q
2026-04-30 DEFA14A
2026-04-30 DEF 14A
2026-04-30 ARS
2026-04-20 PRE 14A
2026-04-07 8-K
2026-03-26 S-8
2026-03-26 8-K
2026-03-26 10-K

Executive team

NameTitleCompensationGender
Mark T. Iwicki Chief Executive Officer & Director 1M male
Christopher H. Cabell FACC President, Head of Research & Development and Chief Medical Officer 782.1K
David John McIntyre Chief Financial Officer 668.3K male
Timothy J. Pigot Chief Commercial & Strategy Officer male
Jeffrey J. Kagy Chief Human Resources Officer male
Chadwick J. Orevillo Executive Vice President & Head of Development Operations male
John Adams Chief Scientific Officer
ESG Rating
B
BIOTECHNOLOGY
Rank: 183 out of 710
2026
E (Environmental)
72.4 / 56.3
Company / Sector avg.
S (Social)
70.2 / 62.4
Company / Sector avg.
G (Governance)
72.2 / 60.9
Company / Sector avg.
ESG Total
71.6 / 59.9
Company / Sector avg.
ESG Score History BIOTECHNOLOGY
Benchmark vs Sector
Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend history

Earnings history

Earnings reports

Stock splits