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Eton Pharmaceuticals, Inc. (ETON)

USD38.12 +0.61 (+1.61%)
US NASDAQ Healthcare Drug Manufacturers - Specialty & Generic
Address 21925 W. Field Parkway 60010-7278
Deer Park, IL, US
CEO Sean E. Brynjelsen
IPO 2018-11-14
CIK 1710340 ISIN US29772L1089

Explore sections of this company profile

Description

Eton Pharmaceuticals, Inc., a pharmaceutical company, focuses on developing and commercializing treatments for rare diseases. Its commercial rare disease products include Increlex for the treatment of severe primary igf-1 deficiency; Alkindi Sprinkle for adrenal insufficiency; Khindivi for adrenocortical insufficiency; Galzin for Wilson disease; PKU Golike for phenylketonuria; Carglumic Acid for N-acetylglutamate synthase deficiency; Betaine Anhydrous for homocystinuria; and Nitisinone for tyrosinemia type 1. The company is also developing various product candidates, which are in late-stage development, including ET-600 for diabetes insipidus; Amglidia for neonatal diabetes mellitus; ET-700 for Wilson disease; ET-800 for adrenal insufficiency; and ZENEO hydrocortisone autoinjector for adrenal crisis. Eton Pharmaceuticals, Inc. was incorporated in 2017 and is based in Deer Park, Illinois.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
USD38.12 +0.61 (+1.61%)
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Volume Profile
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Liquidity & share structure
Average Volume
410.7K
Beta
0.89
Float Shares
23.21M
Free Float %
84.8%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
-2.79% -3.14% +10.47% +75.51% +76.86% +77.17% +75.00% +746.33% +263.15% +379.36% +379.36%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
vs.
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Analyst Consensus (6 ratings, all time) Buy
Price Targets & DCF
Current price
38.12
Low 15.00 -60.6%
Consensus 25.00 -34.4%
Median 25.00 -34.4%
High 35.00 -8.2%
DCF (Levered) 3.11 -91.8%

DCF figures are point estimates: small changes in growth or discount-rate assumptions move them materially. Read them as a reference, not a precise target.

Ratings Trend (MoM) 100% Bullish
Rating 2026-05 Change
Strong Buy 0 0
Buy 3 0
Hold 0 0
Sell 0 0
Strong Sell 0 0
Price Target Summary
Period # Analysts Avg Target
Last Month
Last Quarter
Last Year 1
35.00
-8.2%
All Time 5
15.60
-59.1%
Quality scores
Altman Z-Score
6.83
Safe zone
Piotroski F-Score
4 / 9
Average
MOAT Score
2 / 10
No MOAT
Composite Rating
C-
Overall Score
1 / 5
Low
DCF Score
3 / 5
Medium
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
2 / 5
Medium
P/E Score
1 / 5
Low
P/Book Score
1 / 5
Low
Operational MOAT
✗ Below peers
  • Revenue growth Drug Manufacturers - Specialty & Generic: +6.8%
    +104.9% Q1'26: +40.4% (vs Q1'25)
  • EPS growth Drug Manufacturers - Specialty & Generic: +16.5%
    -13.3% Q1'26: +185.5% (vs Q1'25)
  • FCF margin FCF growth · Drug Manufacturers - Specialty & Generic: +32.3%
    -2.4% Q1'26: +30.2% (vs Q1'25)
  • EBIT margin Drug Manufacturers - Specialty & Generic: +13.0%
    +0.1% Q1'26: +0.0% (vs Q1'25)
  • ROIC Drug Manufacturers - Specialty & Generic: +6.5%
    +0.2% Q1'26: +0.0% (vs Q1'25)
  • Share dilution Drug Manufacturers - Specialty & Generic: +0.0%
    +3.9% Q1'26: +17.3% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Drug Manufacturers - Specialty & Generic: -0.10×
    7.54× Q1'26: 1.27× (vs Q1'25)
Valuation Multiples From To
Price Forecast (3Y) From To
Model
Adjust
P/E
Theoretical Return — If Invested Today

* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.

DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (0.82) × ERP
WACC = 96% × Ke + 4% × Kd (15.4%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Current price: 38.12
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2019
actual
Dec 2020
actual
Dec 2021
actual
Dec 2022
actual
Dec 2023
actual
Dec 2024
actual
Dec 2025
actual
Dec 2026
2 Rev. Ana.
2 EPS Ana.
Dec 2027
2 Rev. Ana.
2 EPS Ana.
Dec 2028
3 Rev. Ana.
3 EPS Ana.
Dec 2029
2 Rev. Ana.
1 EPS Ana.
Dec 2030
1 Rev. Ana.
1 EPS Ana.
Revenue
959.0K
est: 1.17M (-18.1%)
39.0K
est: 1.16M (-96.6%)
21.83M
est: 23.30M (-6.3%)
21.25M
est: 21.80M (-2.5%)
31.64M
est: 31.38M (+0.8%)
39.01M
est: 37.91M (+2.9%)
79.95M
est: 79.27M (+0.9%)
108.36M
108.27M – 108.44M
+36.7% YoY
172.10M
163.72M – 180.47M
+58.8% YoY
230.54M
229.75M – 231.33M
+34.0% YoY
319.11M
306.74M – 331.08M
+38.4% YoY
405.98M
390.24M – 421.21M
+27.2% YoY
EBITDA
-18.15M
est: -327.4K (-5,444.2%)
-26.46M
est: -324.8K (-8,045.8%)
-1.03M
est: -6.52M (+84.2%)
-6.49M
est: -6.10M (-6.3%)
-291.0K
est: -2.18M (+86.7%)
-1.45M
est: -2.63M (+44.9%)
4.12M
est: -5.51M (+174.7%)
-7.53M
-7.54M – -7.52M
-36.7% YoY
-11.96M
-12.54M – -11.38M
-58.8% YoY
-16.02M
-16.07M – -15.96M
-34.0% YoY
-22.17M
-23.01M – -21.31M
-38.4% YoY
-28.21M
-29.27M – -27.12M
-27.2% YoY
EBIT
-18.60M
est: -365.5K (-4,989.6%)
-27.11M
est: -362.6K (-7,377.7%)
-1.50M
est: -7.28M (+79.5%)
-8.26M
est: -6.81M (-21.3%)
-1.19M
est: -3.52M (+66.1%)
-2.60M
est: -4.25M (+38.9%)
72.0K
est: -8.89M (+100.8%)
-12.15M
-12.16M – -12.14M
-36.7% YoY
-19.29M
-20.23M – -18.35M
-58.8% YoY
-25.84M
-25.93M – -25.76M
-34.0% YoY
-35.77M
-37.11M – -34.39M
-38.4% YoY
-45.51M
-47.22M – -43.75M
-27.2% YoY
Net Income
-18.32M
est: -29.69M (+38.3%)
-27.97M
est: -33.02M (+15.3%)
-1.96M
est: -2.07M (+5.6%)
-9.02M
est: -9.87M (+8.6%)
-936.0K
est: -6.69M (+86.0%)
-3.82M
est: -4.13M (+7.4%)
-4.60M
est: 9.96M (-146.2%)
26.13M
16.44M – 28.76M
+162.5% YoY
54.09M
41.82M – 57.29M
+107.0% YoY
78.88M
60.09M – 91.80M
+45.8% YoY
117.32M
111.41M – 123.04M
+48.7% YoY
157.82M
149.87M – 165.51M
+34.5% YoY
SGA
7.55M
est: 77.22M (-90.2%)
12.76M
est: 76.60M (-83.3%)
14.47M
est: 1.54B (-99.1%)
18.58M
est: 1.44B (-98.7%)
18.93M
est: 19.87M (-4.7%)
22.75M
est: 24.01M (-5.2%)
35.82M
est: 50.20M (-28.7%)
68.63M
68.57M – 68.68M
+36.7% YoY
108.99M
103.69M – 114.30M
+58.8% YoY
146.01M
145.51M – 146.51M
+34.0% YoY
202.10M
194.27M – 209.69M
+38.4% YoY
257.12M
247.16M – 266.77M
+27.2% YoY
EPS
-1.02
est: -1.15 (+11.0%)
-1.33
est: -1.28 (-4.3%)
-0.08
est: -0.08 (+3.0%)
-0.36
est: -0.38 (+5.3%)
-0.04
est: -0.26 (+85.9%)
-0.15
est: -0.13 (-18.4%)
-0.17
est: 0.37 (-145.9%)
0.85
0.61 – 1.07
+128.4% YoY
1.85
1.55 – 2.13
+118.5% YoY
2.75
2.23 – 3.41
+48.9% YoY
4.36
4.14 – 4.57
+58.5% YoY
5.87
5.57 – 6.15
+34.5% YoY
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-14 C- 1/5 3/5 1/5 1/5 2/5 1/5 1/5
2026-05-13 C- 1/5 3/5 1/5 1/5 2/5 1/5 1/5
2026-05-12 C- 1/5 3/5 1/5 1/5 2/5 1/5 1/5
2026-05-11 C- 1/5 3/5 1/5 1/5 2/5 1/5 1/5
2026-05-08 C- 1/5 3/5 1/5 1/5 2/5 1/5 1/5
2026-05-07 C- 1/5 3/5 1/5 1/5 2/5 1/5 1/5
2026-05-06 C- 1/5 3/5 1/5 1/5 2/5 1/5 1/5
2026-05-05 C- 1/5 2/5 1/5 1/5 2/5 1/5 1/5
2026-05-04 C- 1/5 3/5 1/5 1/5 2/5 1/5 1/5
2026-05-01 C- 1/5 3/5 1/5 1/5 1/5 1/5 1/5
2026-04-30 C- 1/5 3/5 1/5 1/5 1/5 1/5 1/5
2026-04-29 C- 1/5 3/5 1/5 1/5 1/5 1/5 1/5
2026-04-28 C- 1/5 3/5 1/5 1/5 1/5 1/5 1/5
2026-04-27 C- 1/5 3/5 1/5 1/5 1/5 1/5 1/5
2026-04-24 C- 1/5 3/5 1/5 1/5 1/5 1/5 1/5
2026-04-23 C- 1/5 3/5 1/5 1/5 1/5 1/5 1/5
2026-04-22 C- 1/5 3/5 1/5 1/5 1/5 1/5 1/5
2026-04-21 C- 1/5 3/5 1/5 1/5 1/5 1/5 1/5
2026-04-20 C- 1/5 3/5 1/5 1/5 1/5 1/5 1/5
2026-04-17 C- 1/5 3/5 1/5 1/5 1/5 1/5 1/5
2026-04-16 C- 1/5 3/5 1/5 1/5 1/5 1/5 1/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
5.65M
OE per share TTM
0.17
Owner's Yield
0.69%
Maintenance CapEx ratio
3.84%
Maint CapEx / Avg PPE
1.9%

Ownership Overview

Ownership breakdown
At a glance
Institutional holders
52
Total invested
88.27M
Insider transactions (90d)
1
Beneficial owners (>5%)
17
Beneficial owners (>5%)
# Reporting person Amount owned % of class Sole voting Shared voting Sole dispositive Shared dispositive Type Citizenship Filing date SEC filing
1 Private Capital Management, LLC (46-3167283) 3.63M 10.34% 2.08M 1.55M 2.08M 1.55M IA Delaware 2024-01-09
2 Imprimis Pharmaceuticals, Inc. 3.50M 20.70% 3.50M 3.50M CO State of Delaware 2018-11-23
3 20-5648796 2.39M 9.69% 13.00 2.39M CO Massachusetts 2022-01-24
4 The Vanguard Group - 23-1945930 1.81M 5.15% 54.8K 1.73M 79.6K IA Pennsylvania 2024-02-13
5 EcoR1 Capital, LLC 1.40M 11.00% 1.40M IA, OO Delaware 2024-12-09
6 Oleg Nodelman 1.40M 11.00% 1.40M HC, IN Delaware 2024-12-09
7 Brynjelsen 1.37M 7.60% 1.37M 1.37M IN United States of America 2020-02-04
8 EcoR1 Capital Fund Qualified, L.P. 1.32M 11.00% PN Delaware 2024-12-09
9 13-3127734 1.20M 4.46% 1.12M 1.20M HC Delaware 2022-02-10
10 26-0385758 1.20M 4.46% 1.12M 1.20M IA Delaware 2022-02-10
11 Peter A. Appel 1.08M 4.48% 1.08M 1.08M IN United States 2021-02-16
12 Marathon Asset Management, L.P. 833.3K 4.50% 833.3K 833.3K IA Delaware United States 2017-02-14
13 BARCLAYS GLOBAL INVESTORS, NA. 771.1K 6.66% 1.08M 1.08M BK Massachusetts 2018-09-07
14 Ophir Global Opportunities Fund 768.9K 2.80% 768.9K 768.9K OO Australia 2024-10-08
15 Kevin R. Hanson 200.0K 0.05% 5.00 IN Massachusetts 2021-06-17
16 1 9.00 11.00% 881.7K 881.7K IN Massachusetts 2019-05-24
17 Opaleye Management Inc. 9.00 11.00% 881.7K 881.7K CO Massachusetts 2019-05-24

Institutional Activity (13F)

Institutional ownership trend From To
13F snapshot — 2026 Q1
Investors holding
52
-52 vs prev Q
New positions
12
Closed positions
64
Increased
27
Reduced
15
Put/Call ratio
0.83
Calls held
20.8K
Puts held
17.3K
Top institutional holders
# Investor Shares / Δ Mkt value / Δ Own% / Δ Weight% / Δ Avg px / Perf. Hold / Status
1 OPALEYE MANAGEMENT INC. 2.86M +— (+0.0%) 48.36M -13.8M (-22.2%) 10.63% +0.000 pp 6.38% -2.406 pp USD5.51 +206.9% 29 qtrs
2 ECOR1 CAPITAL, LLC 2.03M +— (+0.0%) 34.34M -9.8M (-22.2%) 7.55% +0.000 pp 1.56% -0.560 pp USD11.30 +49.6% 6 qtrs
3 BLACKROCK, INC. 1.74M +34.5K (+2.0%) 29.40M -7.6M (-20.6%) 6.47% +0.129 pp 0.00% 0.000 pp USD13.66 +23.8% 6 qtrs
4 VANGUARD GROUP INC 1.35M +4.6K (+0.3%) 22.81M -6.4M (-21.9%) 5.01% +0.017 pp 0.00% 0.000 pp USD8.48 +99.4% 28 qtrs
5 NANTAHALA CAPITAL MANAGEMENT, LLC 1.18M +— (+0.0%) 19.89M -5.7M (-22.2%) 4.37% +0.000 pp 0.66% -0.230 pp USD5.01 +237.5% 7 qtrs
6 GEODE CAPITAL MANAGEMENT, LLC 565.1K -9.0K (-1.6%) 9.56M -2.9M (-23.4%) 2.10% -0.033 pp 0.00% 0.000 pp USD10.39 +62.8% 23 qtrs
7 STATE STREET CORP 501.9K +63.5K (+14.5%) 8.49M -1.0M (-10.9%) 1.87% +0.236 pp 0.00% +0.000 pp USD14.91 +13.4% 23 qtrs
8 MORGAN STANLEY 493.9K -92.1K (-15.7%) 8.35M -4.4M (-34.4%) 1.84% -0.343 pp 0.00% 0.000 pp USD14.91 +13.4% 29 qtrs
9 WESTSIDE INVESTMENT MANAGEMENT, INC. 470.9K -1.6K (-0.3%) 7.96M -2.3M (-22.4%) 1.75% -0.006 pp 1.27% -0.367 pp USD3.62 +367.1% 24 qtrs
10 OBERWEIS ASSET MANAGEMENT INC/ 431.3K +238.9K (+124.2%) 7.29M +3.1M (+74.5%) 1.60% +0.889 pp 0.27% +0.107 pp USD19.06 -11.3% 2 qtrs
11 THOMPSON SIEGEL & WALMSLEY LLC 408.5K -10.0K (-2.4%) 6.91M -2.2M (-24.0%) 1.52% -0.037 pp 0.12% -0.031 pp USD11.72 +44.3% 7 qtrs
12 BNP PARIBAS ARBITRAGE, SNC 277.5K +47.7K (+20.7%) 4.69M -301.5K (-6.0%) 1.03% +0.177 pp 0.00% -0.001 pp USD18.35 -7.8% 23 qtrs
13 NORTHERN TRUST CORP 231.8K -13.2K (-5.4%) 3.92M -1.4M (-26.4%) 0.86% -0.049 pp 0.00% 0.000 pp USD12.15 +39.2% 26 qtrs
14 CANNELL CAPITAL LLC 216.9K -238.5K (-52.4%) 3.67M -6.2M (-62.9%) 0.81% -0.887 pp 1.78% +0.270 pp USD14.43 +17.2% 5 qtrs
15 RENAISSANCE TECHNOLOGIES LLC 205.7K -118.9K (-36.6%) 3.48M -3.6M (-50.7%) 0.76% -0.442 pp 0.01% -0.004 pp USD11.57 +46.2% 12 qtrs
16 GOLDMAN SACHS GROUP INC 196.3K +6.1K (+3.2%) 3.32M -813.5K (-19.7%) 0.73% +0.023 pp 0.00% 0.000 pp USD16.84 +0.4% 10 qtrs
17 DIAMETRIC CAPITAL, LP 193.2K +93.8K (+94.5%) 3.27M +1.1M (+51.4%) 0.72% +0.349 pp 0.88% +0.075 pp USD15.97 +5.9% 4 qtrs
18 JPMORGAN CHASE & CO 185.4K -166.0K (-47.2%) 3.14M -4.5M (-58.9%) 0.69% -0.617 pp 0.00% 0.000 pp USD16.19 +4.4% 8 qtrs
19 LUMBARD & KELLNER, LLC 174.9K -1.4K (-0.8%) 2.96M -872.7K (-22.8%) 0.65% -0.005 pp 1.04% -0.373 pp USD21.73 -22.2% 2 qtrs
20 ARISTIDES CAPITAL LLC 161.4K -6.2K (-3.7%) 2.73M -911.8K (-25.0%) 0.60% -0.023 pp 0.48% -0.042 pp USD5.11 +230.9% 7 qtrs
21 BANK OF NEW YORK MELLON CORP 127.7K -1.5K (-1.1%) 2.16M -647.7K (-23.1%) 0.47% -0.006 pp 0.00% 0.000 pp USD9.16 +84.6% 23 qtrs
22 UBS GROUP AG 126.7K -93.7K (-42.5%) 2.14M -2.6M (-55.3%) 0.47% -0.348 pp 0.00% 0.000 pp USD13.58 +24.5% 28 qtrs
23 JEFFERIES FINANCIAL GROUP INC. 118.3K +29.9K (+33.8%) 2.00M +78.7K (+4.1%) 0.44% +0.111 pp 0.01% +0.001 pp USD20.51 -17.6% 5 qtrs
24 BANK OF AMERICA CORP /DE/ 104.8K +30.1K (+40.4%) 1.77M +149.8K (+9.2%) 0.39% +0.112 pp 0.00% +0.000 pp USD17.58 -3.8% 9 qtrs
25 WOODLINE PARTNERS LP 95.5K +95.5K (+100.0%) 1.61M +1.6M (+100.0%) 0.36% +0.355 pp 0.01% +0.006 pp USD16.91 +0.0% 1 qtrs NEW
26 BRIDGEWAY CAPITAL MANAGEMENT, LLC 84.0K -25.0K (-22.9%) 1.42M -948.2K (-40.0%) 0.31% -0.093 pp 0.03% -0.021 pp USD4.87 +247.2% 20 qtrs
27 WELLINGTON MANAGEMENT GROUP LLP 81.2K -7.0K (-8.0%) 1.37M -543.9K (-28.4%) 0.30% -0.026 pp 0.00% 0.000 pp USD18.89 -10.5% 4 qtrs
28 MILLENNIUM MANAGEMENT LLC 79.3K +63.5K (+400.1%) 1.34M +996.8K (+289.2%) 0.30% +0.236 pp 0.00% +0.000 pp USD17.87 -5.4% 5 qtrs
29 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 77.2K -62.0 (-0.1%) 1.31M -373.5K (-22.2%) 0.29% 0.000 pp 0.00% 0.000 pp USD12.27 +37.8% 15 qtrs
30 TWO SIGMA INVESTMENTS, LP 76.6K -209.8K (-73.3%) 1.30M -4.9M (-79.2%) 0.28% -0.780 pp 0.00% -0.007 pp USD15.86 +6.6% 10 qtrs
31 CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD. 76.6K -67.2K (-46.7%) 1.30M -1.8M (-58.6%) 0.28% -0.250 pp 0.00% -0.006 pp USD10.98 +54.0% 10 qtrs
32 CITADEL ADVISORS LLC 74.1K +74.1K (+100.0%) 1.25M +1.3M (+100.0%) 0.28% +0.276 pp 0.00% +0.000 pp USD16.91 +0.0% 1 qtrs NEW
33 SUSQUEHANNA INTERNATIONAL GROUP, LLP 62.4K -30.3K (-32.7%) 1.06M -959.2K (-47.6%) 0.23% -0.113 pp 0.00% 0.000 pp USD14.25 +18.7% 10 qtrs
34 NUVEEN, LLC 58.9K +— (+0.0%) 996.3K -284.0K (-22.2%) 0.22% +0.000 pp 0.00% 0.000 pp USD14.25 +18.7% 3 qtrs
35 JANE STREET GROUP, LLC 58.1K -12.9K (-18.2%) 981.7K -559.9K (-36.3%) 0.22% -0.048 pp 0.00% 0.000 pp USD21.73 -22.2% 13 qtrs
36 BARCLAYS PLC 51.4K +14.6K (+39.8%) 870.0K +70.2K (+8.8%) 0.19% +0.054 pp 0.00% +0.000 pp USD14.36 +17.8% 5 qtrs
37 RUSSELL INVESTMENTS GROUP, LTD. 49.7K -5.2K (-9.4%) 840.3K -351.9K (-29.5%) 0.18% -0.019 pp 0.00% 0.000 pp USD19.26 -12.2% 3 qtrs
38 PRELUDE CAPITAL MANAGEMENT, LLC 45.3K +3.5K (+8.2%) 766.4K -143.5K (-15.8%) 0.17% +0.013 pp 0.06% -0.015 pp USD13.32 +27.0% 5 qtrs
39 ANCHOR CAPITAL ADVISORS LLC 40.7K +3.9K (+10.6%) 687.7K -111.5K (-14.0%) 0.15% +0.015 pp 0.02% -0.003 pp USD13.93 +21.4% 5 qtrs
40 XTX TOPCO LTD 32.5K +8.1K (+33.3%) 550.0K +19.8K (+3.7%) 0.12% +0.030 pp 0.01% -0.013 pp USD20.53 -17.6% 10 qtrs
41 BLAIR WILLIAM & CO/IL 32.4K +— (+0.0%) 547.9K -156.2K (-22.2%) 0.12% +0.000 pp 0.00% 0.000 pp USD6.10 +177.2% 19 qtrs
42 RHUMBLINE ADVISERS 30.4K -5.7K (-15.7%) 514.7K -270.3K (-34.4%) 0.11% -0.021 pp 0.00% 0.000 pp USD14.25 +18.7% 3 qtrs
43 WELLS FARGO & COMPANY/MN 28.3K +11.6K (+69.3%) 478.4K +115.3K (+31.8%) 0.11% +0.043 pp 0.00% +0.000 pp USD16.10 +5.0% 5 qtrs
44 STATE OF WISCONSIN INVESTMENT BOARD 24.6K +24.6K (+100.0%) 416.2K +416.2K (+100.0%) 0.09% +0.092 pp 0.00% +0.001 pp USD16.91 +0.0% 1 qtrs NEW
45 AQUATIC CAPITAL MANAGEMENT LLC 22.8K -13.5K (-37.2%) 385.6K -403.9K (-51.2%) 0.08% -0.050 pp 0.01% -0.004 pp USD14.35 +17.8% 3 qtrs
46 ESSEX INVESTMENT MANAGEMENT CO LLC 20.2K +— (+0.0%) 341.3K -97.3K (-22.2%) 0.08% +0.000 pp 0.05% -0.015 pp USD3.76 +349.7% 11 qtrs
47 INVESCO LTD. 19.7K +6.2K (+46.1%) 333.0K +40.1K (+13.7%) 0.07% +0.023 pp 0.00% +0.000 pp USD15.09 +12.1% 3 qtrs
48 JUNCTURE WEALTH STRATEGIES, LLC 19.0K +2.0K (+12.0%) 321.2K -47.5K (-12.9%) 0.07% +0.008 pp 0.11% -0.018 pp USD21.22 -20.3% 2 qtrs
49 BRIDGE CITY CAPITAL, LLC 18.6K +1.9K (+11.6%) 314.5K -47.8K (-13.2%) 0.07% +0.007 pp 0.09% -0.004 pp USD21.23 -20.3% 2 qtrs
50 DEUTSCHE BANK AG\ 18.2K +850.0 (+4.9%) 308.6K -69.5K (-18.4%) 0.07% +0.003 pp 0.00% +0.000 pp USD14.37 +17.7% 3 qtrs
51 CHICAGO TRUST CO NA 16.7K +— (+0.0%) 282.4K -80.5K (-22.2%) 0.06% +0.000 pp 0.04% -0.007 pp USD5.04 +235.5% 18 qtrs
52 LOS ANGELES CAPITAL MANAGEMENT LLC 14.6K +14.6K (+100.0%) 267.0K +267.0K (+100.0%) 0.05% +0.054 pp 0.00% +0.001 pp USD16.91 +0.0% 1 qtrs NEW
53 VOLEON CAPITAL MANAGEMENT LP 15.6K +4.6K (+42.3%) 263.5K +25.5K (+10.7%) 0.06% +0.017 pp 0.01% 0.000 pp USD20.30 -16.7% 2 qtrs
54 METLIFE INVESTMENT MANAGEMENT, LLC 15.5K +— (+0.0%) 262.7K -74.9K (-22.2%) 0.06% +0.000 pp 0.00% 0.000 pp USD14.25 +18.7% 3 qtrs
55 PRICE T ROWE ASSOCIATES INC /MD/ 15.4K +1.8K (+13.6%) 260.0K -34.0K (-11.6%) 0.06% +0.007 pp 0.00% +0.000 pp USD14.90 +13.5% 3 qtrs
56 D. E. SHAW & CO., INC. 15.3K +15.3K (+100.0%) 259.2K +259.2K (+100.0%) 0.06% +0.057 pp 0.00% +0.000 pp USD16.91 +0.0% 1 qtrs NEW
57 PDT PARTNERS, LLC 14.9K +— (+0.0%) 251.8K -71.8K (-22.2%) 0.06% +0.000 pp 0.02% -0.004 pp USD12.98 +30.3% 4 qtrs
58 TWO SIGMA ADVISERS, LP 14.7K -154.2K (-91.3%) 248.6K -3.4M (-93.2%) 0.05% -0.573 pp 0.00% -0.007 pp USD16.96 -0.3% 5 qtrs
59 SQUAREPOINT OPS LLC 13.5K -46.2K (-77.4%) 228.0K -1.1M (-82.4%) 0.05% -0.172 pp 0.00% -0.001 pp USD13.37 +26.5% 4 qtrs
60 POINT72 ASSET MANAGEMENT, L.P. 12.9K +12.9K (+100.0%) 218.6K +218.6K (+100.0%) 0.05% +0.048 pp 0.00% +0.000 pp USD16.91 +0.0% 1 qtrs NEW
61 CANADA PENSION PLAN INVESTMENT BOARD 12.5K +12.5K (+100.0%) 211.4K +211.4K (+100.0%) 0.05% +0.047 pp 0.00% +0.000 pp USD16.91 +0.0% 1 qtrs NEW
62 INTECH INVESTMENT MANAGEMENT LLC 12.4K +1.2K (+11.1%) 210.0K -32.8K (-13.5%) 0.05% +0.005 pp 0.00% 0.000 pp USD14.52 +16.5% 3 qtrs
63 RAYMOND JAMES FINANCIAL INC 12.3K -74.8K (-85.9%) 207.1K -1.7M (-89.1%) 0.05% -0.278 pp 0.00% -0.001 pp USD13.19 +28.2% 5 qtrs
64 MIRAE ASSET GLOBAL ETFS HOLDINGS LTD. 11.9K -143.0 (-1.2%) 200.6K -60.3K (-23.1%) 0.04% -0.001 pp 0.00% 0.000 pp USD14.25 +18.7% 3 qtrs
65 QUANTUM PRIVATE WEALTH, LLC 11.5K +— (+0.0%) 194.5K -55.4K (-22.2%) 0.04% +0.000 pp 0.06% -0.016 pp USD2.62 +545.4% 15 qtrs
66 ENVESTNET ASSET MANAGEMENT INC 10.9K -433.0 (-3.8%) 185.1K -62.2K (-25.1%) 0.04% -0.002 pp 0.00% +0.000 pp USD13.55 +24.8% 5 qtrs
67 JUMP FINANCIAL, LLC 10.6K +10.6K (+100.0%) 178.4K +178.4K (+100.0%) 0.04% +0.039 pp 0.00% +0.002 pp USD16.91 +0.0% 1 qtrs NEW
68 MAN GROUP PLC 10.5K -2.2K (-17.2%) 177.1K -97.8K (-35.6%) 0.04% -0.008 pp 0.00% 0.000 pp USD13.05 +29.6% 4 qtrs
69 NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO 10.0K +— (+0.0%) 169.1K -48.2K (-22.2%) 0.04% +0.000 pp 0.00% +0.000 pp USD14.25 +18.7% 3 qtrs
70 QUANTBOT TECHNOLOGIES LP 9.4K -2.2K (-18.9%) 158.2K -92.4K (-36.9%) 0.03% -0.008 pp 0.01% -0.002 pp USD13.86 +22.0% 4 qtrs
71 STATE OF WYOMING 8.2K +2.7K (+50.0%) 138.0K +19.8K (+16.7%) 0.03% +0.010 pp 0.02% +0.002 pp USD14.29 +18.3% 4 qtrs
72 NEW YORK STATE COMMON RETIREMENT FUND 8.1K +— (+0.0%) 137.0K -39.0K (-22.2%) 0.03% +0.000 pp 0.00% +0.000 pp USD14.25 +18.7% 3 qtrs
73 POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY 7.2K +— (+0.0%) 121.9K -34.7K (-22.2%) 0.03% +0.000 pp 0.00% 0.000 pp USD15.36 +10.1% 3 qtrs
74 STATE OF ALASKA, DEPARTMENT OF REVENUE 6.9K +5.5K (+388.6%) 117.0K +87.0K (+290.0%) 0.03% +0.021 pp 0.00% +0.001 pp USD17.90 -5.5% 2 qtrs
75 SG AMERICAS SECURITIES, LLC 6.5K +6.5K (+100.0%) 109.0K +109.0K (+100.0%) 0.02% +0.024 pp 0.00% +0.000 pp USD16.91 +0.0% 1 qtrs NEW
76 CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD. 4.4K +4.4K (+100.0%) 73.9K +73.9K (+100.0%) 0.02% +0.016 pp 0.01% +0.006 pp USD16.91 +0.0% 1 qtrs NEW
77 QUEST PARTNERS LLC 4.1K -1.0 (0.0%) 70.2K -20.0K (-22.2%) 0.02% +0.000 pp 0.00% -0.002 pp USD13.37 +26.5% 4 qtrs
78 FMR LLC 3.1K -2.6K (-46.0%) 52.0K -71.7K (-58.0%) 0.01% -0.010 pp 0.00% +0.000 pp USD21.13 -20.0% 4 qtrs
79 TOWER RESEARCH CAPITAL LLC (TRC) 3.0K +2.0K (+208.3%) 50.6K +29.5K (+139.9%) 0.01% +0.008 pp 0.00% +0.001 pp USD15.75 +7.4% 23 qtrs
80 CAITONG INTERNATIONAL ASSET MANAGEMENT CO., LTD 2.9K +2.9K (+100.0%) 49.7K +49.7K (+100.0%) 0.01% +0.011 pp 0.01% +0.012 pp USD16.91 +0.0% 4 qtrs
81 LEGAL & GENERAL GROUP PLC 2.7K -121.0 (-4.2%) 46.2K -15.8K (-25.5%) 0.01% 0.000 pp 0.00% +0.000 pp USD14.25 +18.7% 3 qtrs
82 AMERITAS INVESTMENT PARTNERS, INC. 2.2K +— (+0.0%) 36.6K -10.4K (-22.2%) 0.01% +0.000 pp 0.00% 0.000 pp USD14.25 +18.7% 3 qtrs
83 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 1.6K -23.0 (-1.4%) 26.7K -8.1K (-23.3%) 0.01% 0.000 pp 0.00% +0.000 pp USD14.25 +18.7% 3 qtrs
84 CITIGROUP INC 1.5K +240.0 (+19.8%) 24.5K -1.8K (-6.8%) 0.01% +0.001 pp 0.00% +0.000 pp USD14.69 +15.1% 6 qtrs
85 MIRAE ASSET GLOBAL INVESTMENTS CO., LTD. 1.3K +1.3K (+100.0%) 22.0K +22.0K (+100.0%) 0.00% +0.005 pp 0.00% +0.000 pp USD16.91 +0.0% 1 qtrs NEW
86 TRUVESTMENTS CAPITAL LLC 1.2K +— (+0.0%) 20.0K -5.7K (-22.2%) 0.00% +0.000 pp 0.00% -0.001 pp USD6.00 +181.8% 12 qtrs
87 ROYAL BANK OF CANADA 1.0K -478.2K (-99.8%) 17.0K -10.4M (-99.8%) 0.00% -1.778 pp 0.00% -0.002 pp USD21.64 -21.9% 12 qtrs
88 AMALGAMATED BANK 805.00 -71.0 (-8.1%) 14.0K -5.0K (-26.3%) 0.00% 0.000 pp 0.00% +0.000 pp USD14.25 +18.7% 3 qtrs
89 GF FUND MANAGEMENT CO. LTD. 527.00 +527.0 (+100.0%) 8.9K +8.9K (+100.0%) 0.00% +0.002 pp 0.00% +0.000 pp USD16.91 +0.0% 1 qtrs NEW
90 GROUP ONE TRADING, L.P. 500.00 -262.0 (-34.4%) 8.5K -8.1K (-48.9%) 0.00% -0.001 pp 0.00% +0.000 pp USD21.73 -22.2% 6 qtrs
91 JONES FINANCIAL COMPANIES LLLP 221.00 +221.0 (+100.0%) 3.7K +3.7K (+100.0%) 0.00% +0.001 pp 0.00% +0.000 pp USD16.91 +0.0% 1 qtrs NEW
92 ADVISOR GROUP HOLDINGS, INC. 200.00 +— (+0.0%) 3.4K -964.0 (-22.2%) 0.00% +0.000 pp 0.00% +0.000 pp USD14.25 +18.7% 7 qtrs
93 STERLING CAPITAL MANAGEMENT LLC 167.00 +105.0 (+169.4%) 2.8K +1.5K (+109.7%) 0.00% +0.000 pp 0.00% +0.000 pp USD15.92 +6.2% 3 qtrs
94 VERMILLION & WHITE WEALTH MANAGEMENT GROUP, LLC 150.00 +— (+0.0%) 2.5K -723.0 (-22.2%) 0.00% +0.000 pp 0.00% -0.001 pp USD14.25 +18.7% 3 qtrs
95 FARTHER FINANCE ADVISORS, LLC 146.00 +146.0 (+100.0%) 2.5K +2.5K (+100.0%) 0.00% +0.001 pp 0.00% +0.000 pp USD16.90 +0.1% 1 qtrs NEW
96 DAIWA SECURITIES GROUP INC. 89.00 +89.0 (+100.0%) 2.0K +2.0K (+100.0%) 0.00% +0.000 pp 0.00% +0.000 pp USD16.90 +0.1% 1 qtrs NEW
97 US BANCORP \DE\ 54.00 +54.0 (+100.0%) 913.00 +913.0 (+100.0%) 0.00% +0.000 pp 0.00% +0.000 pp USD16.91 +0.0% 1 qtrs NEW
98 PNC FINANCIAL SERVICES GROUP, INC. 51.00 +34.0 (+200.0%) 862.00 +493.0 (+133.6%) 0.00% +0.000 pp 0.00% +0.000 pp USD18.49 -8.5% 2 qtrs
Ownership breakdown by holder

ETF Ownership

Top ETFs holding this stock Held by 68 ETFs in our universe
# ETF Weight Est. AUM exposure TER
1 State Street SPDR S&P Pharmaceuticals ETF XPH 1.28% 6.02M 0.35%
2 First Trust Active Factor Small Cap ETF AFSM 0.62% 697.7K 0.75%
3 Direxion Daily Pharmaceutical & Medical Bull 3X ETF PILL 0.27% 61.9K 1.22%
4 Invesco Russell 2000 Dynamic Multifactor ETF OMFS 0.23% 640.0K 0.39%
5 iShares Micro-Cap ETF IWC 0.22% 3.29M 0.60%
6 American Century Small Cap Growth Insights ETF ACSG 0.19% 48.8K 0.49%
7 Goldman Sachs ActiveBeta U.S. Small Cap Equity ETF GSSC 0.13% 1.32M 0.20%
8 iShares Nasdaq US Biotechnology UCITS ETF BTEE.L 0.07% 51.3K 0.35%
9 iShares Nasdaq US Biotechnology UCITS ETF BTEC.L 0.07% 766.1K 0.35%
10 Invesco NASDAQ Biotech UCITS ETF SBIO.L 0.07% 319.3K 0.40%

Insider Activity

Insider Activity — Latest Quarter
Ratio by transactions
1.00
Neutral
Ratio by volume
1.00
Neutral
Buys
2
Sells
2
Shares acquired
32.2K
Shares disposed
32.2K
Cash buys
Cash sales
Net activity
+0
Insider buys vs sells (history) From To
Recent insider transactions From To
Date Person Role Transaction A/D Security Shares Price Value Owned after D/I Filing
2026-04-21 RIEDEL NORBERT G Director M-Exempt A Common Stock 19,655 8.61 169.2K 67,155 D
2026-02-03 RIEDEL NORBERT G Director X-InTheMoney A Common Stock 30,000 4.42 132.6K 35,000 D
2026-01-14 Krempa David Officer F-InKind D Common Stock 1,942 15.62 30.3K 630,238 D
2026-01-14 Gruber James R. Officer F-InKind D Common Stock 2,293 15.47 35.5K 213,420 D
2026-01-12 RIEDEL NORBERT G Director A-Award A Employee Stock Option (Right to Buy) 12,196 15.47 188.7K 286,496 D
2026-01-12 MAIER PAUL V Director A-Award A Employee Stock Option (Right to Buy) 12,196 15.47 188.7K 286,496 D
2026-01-12 Krempa David Officer A-Award A Employee Stock Option (Right to Buy) 40,655 15.47 628.9K 670,893 D
2026-01-12 Gruber James R. Officer A-Award A Employee Stock Option (Right to Buy) 40,655 15.47 628.9K 254,075 D
2026-01-12 Erdogan-Trinkaus Ipek Officer A-Award A Employee Stock Option (Right to Buy) 40,655 15.47 628.9K 123,878 D
2026-01-12 CASAMENTO CHARLES J Director A-Award A Employee Stock Option (Right to Buy) 12,196 15.47 188.7K 295,171 D
2026-01-12 BRYNJELSEN SEAN Director / Officer / 10% Owner A-Award A Employee Stock Option (Right to Buy) 158,046 15.47 2.44M 3,047,312 D
2026-01-12 Adams Jennifer McKie Director A-Award A Employee Stock Option (Right to Buy) 12,196 15.47 188.7K 170,329 D
2026-01-01 BRYNJELSEN SEAN Director / Officer / 10% Owner F-InKind D Common Stock 5,015 15.39 77.2K 2,889,266 D
2025-12-12 Krempa David Officer F-InKind D Common Stock 6,264 17.00 106.5K 632,180 D
2025-12-12 Gruber James R. Officer F-InKind D Common Stock 4,542 16.99 77.2K 215,713 D
2025-12-12 Erdogan-Trinkaus Ipek Officer F-InKind D Common Stock 85 16.90 1.4K 2,403 D
2025-12-12 BRYNJELSEN SEAN Director / Officer / 10% Owner F-InKind D Common Stock 6,732 16.83 113.3K 2,894,281 D
2025-12-11 Krempa David Officer A-Award A Restricted Stock Units 5,300 0.00 638,468 D
2025-12-11 Gruber James R. Officer A-Award A Restricted Stock Units 5,502 0.00 210,255 D
2025-08-20 Gruber James R. Officer S-Sale D Common Stock 2,631 16.02 42.1K 204,753 D
2025-08-19 Gruber James R. Officer S-Sale D Common Stock 39,082 16.16 631.6K 205,299 D
2025-06-16 Krempa David Officer S-Sale D Common Stock 10,223 14.73 150.6K 612,646 D
2025-06-13 Krempa David Officer S-Sale D Common Stock 6,800 14.77 100.4K 622,869 D
2025-06-12 Krempa David Officer S-Sale D Common Stock 16,977 14.92 253.3K 629,669 D
2025-06-10 Opaleye Management Inc. 10% Owner P-Purchase A Common Stock, par value $0.001 per share 5,000 15.82 79.1K 2,770,000 I
2025-06-05 BRYNJELSEN SEAN Director / Officer / 10% Owner S-Sale D Common Stock 70,000 16.81 1.18M 2,873,513 D
2025-06-04 BRYNJELSEN SEAN Director / Officer / 10% Owner S-Sale D Common Stock 70,000 17.00 1.19M 2,943,513 D
2025-06-03 BRYNJELSEN SEAN Director / Officer / 10% Owner S-Sale D Common Stock 400 19.02 7.6K 3,013,513 D
2025-01-03 RIEDEL NORBERT G Director A-Award A Employee Stock Option (Right to Buy) 25,000 13.00 325.0K 25,000 D
2025-01-03 MAIER PAUL V Director A-Award A Employee Stock Option (Right to Buy) 25,000 13.00 325.0K 25,000 D
2025-01-03 Krempa David Officer A-Award A Restricted Stock Units 25,876 0.00 25,876 D
2025-01-03 Gruber James R. Officer A-Award A Restricted Stock Units 25,876 0.00 25,876 D
2025-01-03 CASAMENTO CHARLES J Director A-Award A Employee Stock Option (Right to Buy) 25,000 13.00 325.0K 25,000 D
2025-01-03 BRYNJELSEN SEAN Director / Officer A-Award A Restricted Stock Units 72,004 0.00 72,004 D
2025-01-03 Adams Jennifer McKie Director A-Award A Employee Stock Option (Right to Buy) 25,000 13.00 325.0K 25,000 D
2024-12-02 Erdogan-Trinkaus Ipek Officer Employee Stock Option (Right to Buy) 75,000 12.46 934.5K 0 D
2024-10-23 Opaleye Management Inc. 10% Owner P-Purchase A Common Stock, par value $0.001 per share 10,000 7.98 79.8K 2,770,000 I
2024-10-08 Opaleye Management Inc. 10% Owner P-Purchase A Common Stock, par value $0.001 per share 3,970 7.03 27.9K 82,070 I
2024-10-07 Opaleye Management Inc. 10% Owner P-Purchase A Common Stock, par value $0.001 per share 10,000 7.22 72.2K 2,730,000 I
2024-10-04 Opaleye Management Inc. 10% Owner P-Purchase A Common Stock, par value $0.001 per share 15,000 6.77 101.6K 2,720,000 I
2024-10-02 Krempa David Officer A-Award A Restricted Stock Units 42,088 0.00 861,374 D
2024-09-11 Opaleye Management Inc. 10% Owner P-Purchase A Common Stock, par value $0.001 per share 45,000 4.75 213.8K 2,705,000
2024-09-10 Opaleye Management Inc. 10% Owner P-Purchase A Common Stock, par value $0.001 per share 50,000 4.65 232.5K 2,660,000
2024-09-09 Opaleye Management Inc. 10% Owner I Common Stock, par value $0.001 per share 0 0.00 2,610,000
2024-02-13 RIEDEL NORBERT G Director A-Award A Stock Option (Right to buy) 30,000 4.42 132.6K 164,555
2024-02-13 MAIER PAUL V Director A-Award A Stock Option (Right to buy) 30,000 4.42 132.6K 164,555
2024-02-13 Krempa David Officer A-Award A Stock Option (Right to buy) 144,677 4.42 639.5K 813,430
2024-02-13 Gruber James R. Officer A-Award A Stock Option (Right to buy) 144,677 4.42 639.5K 374,763
2024-02-13 CASAMENTO CHARLES J Director A-Award A Stock Option (Right to buy) 30,000 4.42 132.6K 164,555
2024-02-13 BRYNJELSEN SEAN Director / Officer A-Award A Stock Option (Right to buy) 438,633 4.42 1.94M 2,473,014
2024-02-13 Adams Jennifer McKie Director A-Award A Stock Option (Right to buy) 30,000 4.42 132.6K 133,133
2023-03-03 RIEDEL NORBERT G Director A-Award A Stock Option (Right to buy) 25,000 3.47 86.8K 134,555
2023-03-03 MAIER PAUL V Director A-Award A Stock Option(Right to buy) 25,000 3.47 86.8K 134,555
2023-03-03 Gruber James R. Officer A-Award A Stock Option (right to buy) 100,086 3.47 347.3K 200,086
2023-03-03 CASAMENTO CHARLES J Director A-Award A Stock Option (Right to buy) 25,000 3.47 86.8K 134,555
2023-03-03 BRYNJELSEN SEAN Director / Officer A-Award A Stock Option (Right to buy) 350,381 3.47 1.22M 1,951,881
2023-03-03 Adams Jennifer McKie Director A-Award A Stock Option (Right to buy) 25,000 3.47 86.8K 103,133
2023-03-01 Krempa David Officer D Employee Stock Option (Right to buy) 158,270 3.78 598.3K 0
2022-09-22 BRYNJELSEN SEAN Director / Officer P-Purchase A Common Stock 10,000 2.10 21.0K 1,040,000
2022-07-12 Gruber James R. Officer A-Award A Restricted Stock Units 40,000 0.00 40,000
2022-07-12 BRYNJELSEN SEAN Officer A-Award A Restricted Stock Units 110,000 0.00 110,000
2022-04-11 Gruber James R. Officer D Employee Stock Options 100,000 3.81 381.0K 0
2022-02-07 Troutman William Wilson Officer A-Award A Stock Option (Right to buy) 15,000 3.78 56.7K 671,200
2022-02-07 RIEDEL NORBERT G Director A-Award A Stock Option (Right to buy) 50,000 3.78 189.0K 109,555
2022-02-07 MAIER PAUL V Director A-Award A Stock Option(Right to buy) 50,000 3.78 189.0K 109,555
2022-02-07 CASAMENTO CHARLES J Director A-Award A Stock Option (Right to buy) 50,000 3.78 189.0K 109,555
2022-02-07 BRYNJELSEN SEAN Director / Officer A-Award A Stock Option(Right to buy) 416,500 3.78 1.57M 1,601,500
2022-02-07 Adams Jennifer McKie Director A-Award A Stock Option (Right to buy) 50,000 3.78 189.0K 78,133
2021-11-17 Opaleye Management Inc. 10% Owner S-Sale D Common Stock, par value $0.001 per share 25,000 4.67 116.7K 2,375,000
2021-11-16 Opaleye Management Inc. 10% Owner S-Sale D Common Stock, par value $0.001 per share 938 4.86 4.6K 85,000
2021-11-15 Opaleye Management Inc. 10% Owner S-Sale D Common Stock, par value $0.001 per share 500 4.80 2.4K 85,938
2021-11-08 Opaleye Management Inc. 10% Owner S-Sale D Common Stock, par value $0.001 per share 50,000 6.10 305.1K 2,414,000
2021-11-05 Opaleye Management Inc. 10% Owner S-Sale D Common Stock, par value $0.001 per share 159,300 6.30 1.00M 2,464,000
2021-11-04 Opaleye Management Inc. 10% Owner S-Sale D Common Stock, par value $0.001 per share 81,700 6.44 525.9K 2,623,300
2021-11-03 Opaleye Management Inc. 10% Owner S-Sale D Common Stock, par value $0.001 per share 110,000 6.53 718.4K 2,705,000
2021-10-12 Opaleye Management Inc. 10% Owner S-Sale D Common Stock, par value $0.001 per share 82,500 5.06 417.2K 2,815,000
2021-10-11 Opaleye Management Inc. 10% Owner S-Sale D Common Stock, par value $0.001 per share 1,601 5.01 8.0K 112,807
2021-10-08 Opaleye Management Inc. 10% Owner S-Sale D Common Stock, par value $0.001 per share 41,000 5.00 205.0K 2,930,000
2021-08-20 Troutman William Wilson Officer P-Purchase A Common Stock 5,000 4.43 22.2K 23,027
2021-08-20 BRYNJELSEN SEAN Director / Officer P-Purchase A Common Stock 10,000 4.32 43.2K 1,030,000
2021-08-06 Opaleye Management Inc. 10% Owner S-Sale D Common Stock, par value $0.001 per share 330,000 5.84 1.93M 2,971,100
2021-08-05 Opaleye Management Inc. 10% Owner S-Sale D Common Stock, par value $0.001 per share 150,000 5.85 878.0K 3,301,100
2021-08-04 Opaleye Management Inc. 10% Owner S-Sale D Common Stock, par value $0.001 per share 100,000 5.75 575.1K 3,451,100
2021-06-15 Opaleye Management Inc. 10% Owner S-Sale D Common Stock, par value $0.001 per share 101,000 8.07 815.1K 3,551,100
2021-06-03 BRYNJELSEN SEAN Director / Officer P-Purchase A Common Stock 5,000 5.96 29.8K 1,030,000
2021-05-27 Opaleye Management Inc. 10% Owner S-Sale D Common Stock, par value $0.001 per share 121,400 8.49 1.03M 3,652,100
2021-05-26 Opaleye Management Inc. 10% Owner S-Sale D Common Stock, par value $0.001 per share 65,500 8.57 561.3K 3,773,500
2021-05-25 Opaleye Management Inc. 10% Owner S-Sale D Common Stock, par value $0.001 per share 46,000 8.53 392.4K 3,839,000
2021-05-03 Troutman William Wilson Officer A-Award A Stock Option(Right to buy) 125,000 8.61 1.08M 656,200
2021-05-03 RIEDEL NORBERT G Director A-Award A Stock Option (Right to buy) 19,655 8.61 169.2K 59,555
2021-05-03 MAIER PAUL V Director A-Award A Stock Option(Right to buy) 19,655 8.61 169.2K 59,555
2021-05-03 CASAMENTO CHARLES J Director A-Award A Stock Option (Right to buy) 19,655 8.61 169.2K 59,555
2021-05-03 BRYNJELSEN SEAN Director / Officer A-Award A Stock Option(Right to buy) 245,000 8.61 2.11M 1,185,000
2021-05-03 Adams Jennifer McKie Director A-Award A Stock Option (Right to buy) 28,133 8.61 242.2K 28,133
2021-04-12 HARROW HEALTH, INC. 10% Owner S-Sale D Common Stock 1,518,000 7.00 10.63M 1,982,000
2021-03-17 Adams Jennifer McKie Director 0 0.00 0
2020-12-31 CASAMENTO CHARLES J Director 0 0.00 0
2020-10-16 Opaleye Management Inc. 10% Owner P-Purchase A Common Stock, par value $0.001 per share 385,000 7.00 2.70M 3,885,000
2020-03-26 Opaleye Management Inc. 10% Owner I Common Stock, $0.001 par value 0 0.00 3,500,000
2020-03-12 Troutman William Wilson Officer A-Award A Stock Option (Right to buy) 186,200 3.58 666.6K 186,200
2020-03-12 RIEDEL NORBERT G Director A-Award A Stock Option (Right to buy) 27,400 3.58 98.1K 27,400
2020-03-12 MAIER PAUL V Director A-Award A Stock Option (Right to buy) 27,400 3.58 98.1K 27,400
2020-03-12 CASAMENTO CHARLES J Director A-Award A Stock Option (Right to buy) 27,400 3.58 98.1K 27,400
2020-03-12 BRYNJELSEN SEAN Director / Officer A-Award A Stock Option (Right to buy) 490,000 3.58 1.75M 490,000
2020-03-12 BAUM MARK L Director A-Award A Stock Option (Right to buy) 27,400 3.58 98.1K 27,400
2019-08-13 BRYNJELSEN SEAN Director / Officer P-Purchase A Common Stock 5,000 6.15 30.8K 1,025,000
2019-08-09 CASAMENTO CHARLES J Director P-Purchase A Common Stock 3,500 6.11 21.4K 71,920
2019-05-21 BRYNJELSEN SEAN Director / Officer P-Purchase A Common Stock 8,600 7.96 68.4K 1,020,000
2019-05-20 BRYNJELSEN SEAN Director / Officer P-Purchase A Common Stock 1,400 7.78 10.9K 1,011,400
2019-02-20 Troutman William Wilson Officer A-Award A Stock option (right to buy) 95,000 7.31 694.5K 95,000
2019-02-20 RIEDEL NORBERT G Director A-Award A Stock option (right to buy) 12,500 7.31 91.4K 12,500
2019-02-20 MAIER PAUL V Director A-Award A Stock option (right to buy) 12,500 7.31 91.4K 12,500
2019-02-20 CASAMENTO CHARLES J Director A-Award A Stock option (right to buy) 12,500 7.31 91.4K 12,500
2019-02-20 BRYNJELSEN SEAN Director / Officer A-Award A Stock option (right to buy) 250,000 7.31 1.83M 250,000
2019-02-20 BAUM MARK L Director A-Award A Stock option (right to buy) 12,500 7.31 91.4K 12,500
2018-11-15 Troutman William Wilson Officer P-Purchase A Common Stock 5,000 6.00 30.0K 5,000
2018-11-15 RIEDEL NORBERT G Director P-Purchase A Common Stock 5,000 6.00 30.0K 59,745
2018-11-15 MAIER PAUL V Director P-Purchase A Common Stock 5,000 6.00 30.0K 59,745
2018-11-15 CASAMENTO CHARLES J Director C-Conversion D Series A Convertible Preferred Stock 8,000 0.00 0
2018-11-15 BRYNJELSEN SEAN Director / Officer C-Conversion A Common Stock 24,940 0.00 24,940
2018-11-15 BAUM MARK L Director P-Purchase A Common Stock 10,000 6.00 60.0K 10,000
2018-11-09 Troutman William Wilson Officer D Stock Option (right to buy) 150,000 1.38 207.0K 0
2018-11-09 RIEDEL NORBERT G Director D Common Stock 0 0.00 54,745
2018-11-09 MAIER PAUL V Director D Restricted Stock Units 25,000 0.00 0
2018-11-09 Imprimis Pharmaceuticals, Inc. 10% Owner D Common Stock 0 0.00 3,500,000
2018-11-09 CASAMENTO CHARLES J Director D Restricted Stock Units 25,000 0.00 0
2018-11-09 BRYNJELSEN SEAN Director / Officer D Common Stock 0 0.00 1,000,000
2018-11-09 BAUM MARK L Director D Restricted Stock Units 25,000 0.00 0
2017-12-08 BRYNJELSEN SEAN Director / Officer I Series A Convertible Preferred Stock 23,000 0.00 0
2017-06-20 CASAMENTO CHARLES J Director D Series A Convertible Preferred Stock 8,000 0.00 0

Executive team

Top executives
EBIT / Employee
1.6K
Shares Outstanding
27.36M

Executive compensation

Executive compensation (annual)
# Year Executive Salary Bonus Stock award Option award Incentive Other Total % Stock-
based
Filing
1 2025 Sean E. Brynjelsen President and Chief Executive Officer 712.4K 936.1K 893.7K 354.8K 17.5K 2.91M 62.78%
2 2025 James R. Gruber Chief Financial Officer 460.5K 336.4K 321.2K 172.0K 108.1K 1.40M 47.03%
3 2025 David C. Krempa Chief Business Officer 460.5K 336.4K 321.2K 172.0K 104.7K 1.39M 47.15%
4 2025 Ipek Erdogan-Trinkaus Chief Commercial Officer 402.7K 150.4K 22.2K 575.3K 0.00%
5 2024 Sean E. Brynjelsen President and Chief Executive Officer 615.5K 1.30M 487.3K 13.8K 2.41M 53.70%
6 2024 David C. Krempa Chief Business Officer 397.8K 250.0K 427.2K 236.2K 13.8K 1.33M 51.11%
7 2024 James R. Gruber Chief Financial Officer 397.8K 427.2K 236.2K 13.8K 1.08M 39.74%
8 2024 Ipek Erdogan-Trinkaus Chief Commercial Officer 33.6K 100.0K 622.1K 19.8K 775.5K 93.12%
9 2023 Sean E. Brynjelsen President and Chief Executive Officer 591.9K 807.6K 334.4K 13.2K 1.75M 46.23%
10 2023 James R. Gruber Chief Financial Officer 379.2K 230.7K 162.1K 13.2K 785.1K 29.38%
11 2023 David C. Krempa Chief Business Officer 372.6K 171.2K 162.1K 12.2K 719.1K 23.81%
12 2022 Sean E. Brynjelsen President and Chief Executive Officer 569.5K 289.3K 962.1K 286.4K 12.2K 2.12M 59.04%
13 2022 David C. Krempa Chief Business Officer 307.9K 105.2K 382.9K 108.7K 12.2K 916.8K 53.23%
14 2022 James R. Gruber Chief Financial Officer 254.6K 105.2K 248.1K 101.1K 3.8K 712.8K 49.56%
15 2021 Sean E. Brynjelsen President and Chief Executive Officer 542.2K 1.40M 138.4K 11.6K 2.09M 66.92%
16 2021 W. Wilson Troutman Chief Financial Officer 337.5K 746.6K 69.0K 11.6K 1.16M 64.10%
17 2020 Sean E. Brynjelsen President and Chief Executive Officer 475.8K 1.31M 218.7K 11.4K 2.01M 64.90%
18 2020 W. Wilson Troutman Chief Financial Officer 277.1K 509.6K 108.0K 11.4K 906.1K 56.24%
19 2019 Sean E. Brynjelsen President and Chief Executive Officer 410.0K 1.34M 186.5K 11.2K 1.95M 68.78%
20 2019 W. Wilson Troutman Chief Financial Officer 242.7K 523.3K 87.5K 11.2K 864.6K 60.52%
21 2018 Sean E. Brynjelsen President and Chief Executive Officer 332.3K 150.6K 10.1K 493.0K 0.00%
22 2018 W. Wilson Troutman Chief Financial Officer 204.5K 82.4K 9.7K 296.6K 0.00%
23 2017 Sean E. Brynjelsen President and Chief Executive Officer 172.1K 210.0K 194.6K 77.4K 654.0K 61.86%
24 2017 W. Wilson Troutman Chief Financial Officer 92.8K 251.2K 36.8K 380.8K 65.96%
CEO compensation breakdown

Proxy statements

Proxy statements (DEF 14A)
Filing date Form type Filing
2026-04-24 DEF 14A
2025-04-25 DEF 14A
2024-04-26 DEF 14A

Recent SEC filings

Recent SEC filings
Filing date Form type Filing
2026-05-14 8-K
2026-05-14 10-Q
2026-04-27 8-K
2026-04-24 DEF 14A
2026-04-22 4
2026-04-16 8-K
2026-04-15 8-K
2026-03-26 SC 13G/A
2026-03-19 8-K
2026-03-19 10-K

Executive team

NameTitleCompensationGender
Sean E. Brynjelsen President, Chief Executive Officer & Director 1M male
James R. Gruber Chief Financial Officer, Treasurer & Secretary 740.5K male
David Krempa Chief Business Officer 737.2K male
Ipek Erdogan-Trinkaus Chief Commercial Officer 575.3K female
Danka Radosavljevic Executive Vice President of Operations
Judith Matthews Executive Vice President of Accounting & Finance female
Scott Grossenbach Senior Vice President of Sales Operations male
ESG Rating
B
BIOTECHNOLOGY
Rank: 294 out of 710
2026
E (Environmental)
49.6 / 56.3
Company / Sector avg.
S (Social)
61.6 / 62.4
Company / Sector avg.
G (Governance)
70.5 / 60.9
Company / Sector avg.
ESG Total
60.6 / 59.9
Company / Sector avg.
ESG Score History BIOTECHNOLOGY
Benchmark vs Sector
Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity
Transaction Date Disclosed Representative District Owner Type Amount Link
2022-10-11 2022-12-01 Thomas Suozzi NY03 Purchase $15,001 - $50,000
Market share among peers
Peer comparison — filtered group (TTM)
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Dividend history

Earnings history

Earnings reports

Stock splits