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Nippon Shinyaku Co., Ltd. (4516.T)

JPY4,013.00 -40.00 (-0.99%)
JP JPX Healthcare Drug Manufacturers - Specialty & Generic
Address 14, Nishinosho-Monguchi-cho 601-8550
Kyoto, JP
CEO Toru Nakai
IPO 2001-01-01
ISIN JP3717600005

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Also trades on Other OTC · NPNKF (USD) Other OTC · NPPNY (USD) Tokyo Stock Exchange · 4516.T (JPY)
Description

Nippon Shinyaku Co., Ltd., an enterprise established in Kyoto, Japan, in 1911, engages globally in the production and distribution of pharmaceutical products and functional foods. Its reach extends across Japan, Switzerland, and various international markets, with operations structured into two core divisions: Pharmaceuticals and Functional Food. The Pharmaceutical division concentrates on a wide array of therapeutic areas, encompassing conditions affecting the urinary system, inflammatory and allergic responses, hematologic malignancies, cardiovascular and metabolic disorders, gastrointestinal issues, and other diverse diseases. Its extensive product catalog features notable treatments such as Zalutia, designed for urinary difficulties arising from benign prostatic hypertrophy; Eviprostat, also for prostatic hypertrophy; Bladderon for frequent urination; and Estracyt, targeting prostate cancer. For erectile dysfunction, it provides Cialis. In hematology and oncology, the company's portfolio includes Vidaza for myelodysplastic syndrome; Cylocide and CylocideN for solid tumors, acute leukemia, and malignant lymphoma; Gazyva, a humanized anti-CD20 monoclonal antibody; Defiterio for sinusoidal obstruction syndrome; and Trisenox and Amnolake for relapsed and refractory acute promyelocytic leukemia. Nippon Shinyaku also offers Uptravi, Adcirca, and Opsumit for the management of pulmonary arterial hypertension, alongside VILTEPSO for muscular dystrophy. Other specialized medications include Lunabel LD and Lunabel ULD for dysmenorrhea; Erizas, a dry powder inhaler for allergic rhinitis; Azunol Gargle liquid, an azulene-based gargling solution; Isobide for oral osmotic diuresis and Meniere's disease; Cephadol for vertigo; Livostin for allergic rhinitis and conjunctivitis; Regtect, aimed at maintaining alcohol abstinence; and Onetram and Tramal for the treatment of cancer and chronic pain. Furthermore, the company actively conducts research, development, and marketing efforts in the fields of gynecology, otorhinolaryngology, and orthopedics. The Functional Food segment broadens the company's offerings, supplying various health-focused ingredients, food preservatives, protein preparations, dietary supplements, and a selection of spices and condiments.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
JPY4,013.00 -40.00 (-0.99%)
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Volume Profile
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Liquidity & share structure
Average Volume
235.2K
Beta
-0.33
Float Shares
47.19M
Free Float %
70.0%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
+0.00% +1.25% -17.14% -15.03% +19.69% -23.76% +23.83% -33.56% -41.65% -22.16% +346.93%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
vs.
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Price Targets & DCF
Current price
4,013.00
DCF (Unlevered) 17,396.94 +333.5%
DCF (Levered) 19,382.78 +383.0%

DCF figures are point estimates: small changes in growth or discount-rate assumptions move them materially. Read them as a reference, not a precise target.

Ratings Trend (MoM) 50% Bullish
Rating 2026-05 Change
Strong Buy 2 0
Buy 2 0
Hold 3 +1
Sell 1 0
Strong Sell 0 0
Quality scores
Altman Z-Score
5.44
Safe zone
Piotroski F-Score
4 / 9
Average
MOAT Score
7 / 10
Strong MOAT
Composite Rating
A+
Overall Score
5 / 5
High
DCF Score
5 / 5
High
ROE Score
4 / 5
High
ROA Score
5 / 5
High
D/E Score
4 / 5
High
P/E Score
3 / 5
Medium
P/Book Score
4 / 5
High
Operational MOAT
✗ Below peers
  • Revenue growth Drug Manufacturers - Specialty & Generic: +6.8%
    +6.6% Q1'26: +12.1% (vs Q1'25)
  • EPS growth Drug Manufacturers - Specialty & Generic: +16.5%
    -8.7% Q1'26: -3.6% (vs Q1'25)
  • FCF margin FCF growth · Drug Manufacturers - Specialty & Generic: +32.3%
    +14.7% Q1'26: +33.4% (vs Q1'25)
  • EBIT margin Drug Manufacturers - Specialty & Generic: +13.0%
    +19.3% Q1'26: +6.1% (vs Q1'25)
  • ROIC Drug Manufacturers - Specialty & Generic: +6.5%
    +12.4% Q1'26: +4.9% (vs Q1'25)
  • Share dilution Drug Manufacturers - Specialty & Generic: +0.0%
    +0.0% Q1'26: +0.3% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Drug Manufacturers - Specialty & Generic: -0.10×
    0.06× Q1'26: 0.15× (vs Q1'25)
Valuation Multiples From To
Price Forecast (3Y) From To
Model
Adjust
P/E
Theoretical Return — If Invested Today

* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.

DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (-0.07) × ERP
WACC = 99% × Ke + 1% × Kd (6.5%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Intrinsic value (base): 15,255.66 Current price: 4,013.00
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Mar 2015
actual
Mar 2016
actual
Mar 2017
actual
Mar 2018
actual
Mar 2019
actual
Mar 2020
actual
Mar 2021
actual
Mar 2022
actual
Mar 2023
actual
Mar 2024
actual
Mar 2025
actual
Mar 2026
7 Rev. Ana.
7 EPS Ana.
Mar 2027
5 Rev. Ana.
2 EPS Ana.
Mar 2028
7 Rev. Ana.
7 EPS Ana.
Mar 2029
4 Rev. Ana.
4 EPS Ana.
Mar 2030
3 Rev. Ana.
2 EPS Ana.
Revenue
79.99B
est: 81.00B (-1.2%)
84.21B
est: 85.90B (-2.0%)
98.78B
est: 99.28B (-0.5%)
101.45B
est: 103.10B (-1.6%)
114.72B
est: 112.47B (+2.0%)
116.64B
est: 117.99B (-1.1%)
121.89B
est: 123.15B (-1.0%)
137.55B
est: 137.91B (-0.3%)
144.18B
est: 142.02B (+1.5%)
148.26B
est: 150.37B (-1.4%)
160.23B
est: 159.54B (+0.4%)
169.63B
168.33B – 170.70B
+6.3% YoY
185.95B
180.19B – 195.13B
+9.6% YoY
182.35B
167.53B – 205.45B
-1.9% YoY
207.24B
206.72B – 207.76B
+13.6% YoY
294.00B
277.62B – 319.68B
+41.9% YoY
EBITDA
11.23B
est: 20.99B (-46.5%)
11.00B
est: 22.26B (-50.6%)
17.93B
est: 25.73B (-30.3%)
19.85B
est: 26.72B (-25.7%)
24.06B
est: 29.15B (-17.4%)
25.14B
est: 30.58B (-17.8%)
30.54B
est: 31.92B (-4.3%)
32.89B
est: 35.74B (-8.0%)
34.29B
est: 36.81B (-6.8%)
36.41B
est: 36.74B (-0.9%)
42.78B
est: 38.98B (+9.7%)
41.45B
41.13B – 41.71B
+6.3% YoY
45.44B
44.03B – 47.68B
+9.6% YoY
44.56B
40.94B – 50.20B
-1.9% YoY
50.64B
50.51B – 50.77B
+13.6% YoY
71.84B
67.84B – 78.11B
+41.9% YoY
EBIT
8.56B
est: 18.14B (-52.8%)
8.55B
est: 19.24B (-55.6%)
15.28B
est: 22.24B (-31.3%)
17.08B
est: 23.09B (-26.0%)
20.65B
est: 25.19B (-18.1%)
21.67B
est: 26.43B (-18.0%)
26.14B
est: 27.59B (-5.3%)
28.30B
est: 30.89B (-8.4%)
29.25B
est: 31.81B (-8.1%)
31.39B
est: 31.37B (+0.0%)
36.76B
est: 33.29B (+10.4%)
35.39B
35.12B – 35.61B
+6.3% YoY
38.80B
37.59B – 40.71B
+9.6% YoY
38.05B
34.95B – 42.86B
-1.9% YoY
43.24B
43.13B – 43.35B
+13.6% YoY
61.34B
57.92B – 66.70B
+41.9% YoY
Net Income
5.88B
est: 6.18B (-4.7%)
6.34B
est: 6.10B (+4.0%)
11.75B
est: 11.52B (+2.0%)
12.95B
est: 13.75B (-5.8%)
16.30B
est: 15.52B (+5.0%)
16.87B
est: 17.04B (-1.0%)
19.54B
est: 20.24B (-3.5%)
24.99B
est: 23.11B (+8.1%)
22.81B
est: 23.31B (-2.1%)
25.85B
est: 27.37B (-5.5%)
32.56B
est: 30.55B (+6.6%)
27.66B
26.53B – 29.64B
-9.5% YoY
25.66B
25.28B – 26.03B
-7.2% YoY
15.81B
9.51B – 20.65B
-38.4% YoY
16.68B
15.84B – 26.29B
+5.5% YoY
41.10B
38.12B – 45.76B
+146.5% YoY
SGA
20.92B
est: 18.94B (+10.4%)
21.56B
est: 20.09B (+7.3%)
23.37B
est: 23.21B (+0.7%)
23.76B
est: 24.11B (-1.4%)
26.07B
est: 26.30B (-0.9%)
27.47B
est: 27.59B (-0.4%)
28.84B
est: 28.80B (+0.2%)
34.82B
est: 32.25B (+8.0%)
33.87B
est: 33.21B (+2.0%)
33.96B
est: 36.18B (-6.2%)
36.99B
est: 38.39B (-3.6%)
40.82B
40.50B – 41.07B
+6.3% YoY
44.74B
43.36B – 46.95B
+9.6% YoY
43.88B
40.31B – 49.43B
-1.9% YoY
49.87B
49.74B – 49.99B
+13.6% YoY
70.74B
66.80B – 76.92B
+41.9% YoY
EPS
87.26
est: 91.66 (-4.8%)
94.10
est: 90.50 (+4.0%)
174.42
est: 170.98 (+2.0%)
192.31
est: 204.07 (-5.8%)
242.03
est: 230.43 (+5.0%)
250.41
est: 252.93 (-1.0%)
290.11
est: 300.47 (-3.4%)
370.97
est: 343.08 (+8.1%)
338.70
est: 369.22 (-8.3%)
383.82
est: 406.31 (-5.5%)
483.40
est: 470.34 (+2.8%)
409.45
393.67 – 439.81
-12.9% YoY
380.74
375.17 – 386.30
-7.0% YoY
234.82
141.16 – 306.35
-38.3% YoY
286.50
235.08 – 390.03
+22.0% YoY
609.80
565.63 – 679.04
+112.8% YoY
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-15 A+ 5/5 5/5 4/5 5/5 4/5 3/5 4/5
2026-05-14 A+ 5/5 5/5 4/5 5/5 4/5 3/5 4/5
2026-05-13 A+ 5/5 5/5 4/5 5/5 4/5 3/5 4/5
2026-05-12 A+ 5/5 5/5 4/5 5/5 4/5 3/5 4/5
2026-05-11 A+ 5/5 5/5 4/5 5/5 4/5 3/5 4/5
2026-05-08 A+ 4/5 5/5 4/5 5/5 3/5 3/5 4/5
2026-05-07 A+ 4/5 5/5 4/5 5/5 3/5 3/5 4/5
2026-05-01 A+ 4/5 5/5 4/5 5/5 3/5 3/5 4/5
2026-04-30 A+ 4/5 5/5 4/5 5/5 3/5 3/5 4/5
2026-04-28 A+ 4/5 5/5 4/5 5/5 3/5 3/5 4/5
2026-04-27 A+ 4/5 5/5 4/5 5/5 3/5 3/5 4/5
2026-04-24 A+ 4/5 5/5 4/5 5/5 3/5 3/5 4/5
2026-04-23 A 4/5 5/5 3/5 5/5 2/5 3/5 4/5
2026-04-22 A 4/5 5/5 3/5 5/5 2/5 3/5 4/5
2026-04-21 A 4/5 5/5 3/5 5/5 2/5 3/5 4/5
2026-04-20 A 4/5 5/5 3/5 5/5 2/5 3/5 4/5
2026-04-17 A 4/5 5/5 3/5 5/5 2/5 3/5 4/5
2026-04-16 A 4/5 5/5 3/5 5/5 2/5 3/5 4/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
30.24B
OE per share TTM
448.68
Owner's Yield
10.59%
Maintenance CapEx ratio
5.82%
Maint CapEx / Avg PPE
22.8%

Ownership Overview

Ownership breakdown

Ownership breakdown not available.

At a glance
Institutional holders
Total invested
Insider transactions (90d)
0
Beneficial owners (>5%)
0
Beneficial owners (>5%)

No beneficial ownership filings recorded.

Institutional Activity (13F)

Institutional ownership trend

Institutional history not available.

Top institutional holders

Top holders not available.

ETF Ownership

Top ETFs holding this stock Held by 110 ETFs in our universe
# ETF Weight Est. AUM exposure TER
1 WisdomTree Japan SmallCap Dividend Fund DFJ 0.25% 958.1K 0.58%
2 Vident International Equity Strategy ETF VIDI 0.14% 558.2K 0.61%
3 iShares MSCI Japan Small Cap UCITS ETF IDJP.L 0.10% 575.1K 0.58%
4 iShares MSCI Japan Small-Cap ETF SCJ 0.09% 243.3K 0.50%
5 Vanguard Global Value Equity Active ETF VVLU.AX 0.09% 825.6K 0.28%
6 Vanguard Global Value Factor ETF VVL.TO 0.08% 468.6K 0.38%
7 WisdomTree Dynamic International SmallCap Equity ETF DDLS 0.08% 348.1K 0.48%
8 Schwab Fundamental International Small Company Index ETF FNDC 0.08% 2.39M 0.39%
9 WisdomTree International SmallCap Dividend Fund DLS 0.07% 714.6K 0.58%
10 Dimensional - International Small Cap Value ETF DISV 0.07% 3.16M 0.42%

Insider Activity

Insider Activity — Latest Quarter

No insider activity available.

Insider buys vs sells (history)

Insider history not available.

Recent insider transactions

No recent insider transactions.

Executive team

Top executives
EBIT / Employee
14.93M
Shares Outstanding
67.40M

Executive compensation

Executive compensation (annual)

Executive compensation not available.

CEO compensation breakdown

No CEO compensation history available.

Proxy statements

Proxy statements (DEF 14A)

No proxy statements available for this company yet.

Recent SEC filings

Recent SEC filings

No SEC filings available for this company yet.

Executive team

NameTitleCompensationGender
Hayato Wada Corporate Officer & Department Manager of Kansai Business Office
Hideyuki Fujii Accounting & Finance Department Manager male
Hitomi Kimura Director of Resource Procurement, Production & Assurance & Director female
Hitoshi Ishizawa GM of Functional Food Division & Director male
Katsumi Noda Corporate Officer & Department Manager of Tokyo Business Office
Kazuyuki Iwata Director of Sales and Marketing & Director
Kazuyuki Yamate Corporate Officer & Head of Digital Transformation Div.
Keiichi Kuwano GM of Research & Development and Director
Manabu Beppu Corporate Officer and Head of R & D Planning and Administration Div.
Masaya Toda Head of Licensing & Alliance Division and Corporate Officer
Takanori Edamitsu Head of Business Management & Sustainability and Director male
Takashi Takaya GM of Personnel, General Affairs, Risk Mgmt, Compliance & Digital Trans and Director male
ESG Score History

No data available for this company.

Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend yield history

Dividend history

Earnings history

Earnings reports

Stock splits