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Tyra Biosciences, Inc. (TYRA)

USD31.93 -0.95 (-2.89%)
US NASDAQ Healthcare Biotechnology
Address 2656 State Street 92008
Carlsbad, CA, US
CEO Todd Harris
Website tyra.bio
IPO 2021-09-15
CIK 1863127 ISIN US90240B1061

Explore sections of this company profile

Description

Tyra Biosciences, Inc. is a preclinical biopharmaceutical company focused on innovating treatments to tackle tumor resistance and enhance patient outcomes in oncology. Its flagship product candidate, TYRA-300, is a highly selective inhibitor of fibroblast growth factor receptor (FGFR)3, specifically engineered for the treatment of muscle-invasive bladder cancer. Beyond this, the company is advancing a pipeline of programs addressing other critical conditions, including FGFR2-related intrahepatic cholangiocarcinoma, FGFR3-associated achondroplasia, REarranged during transfection (RET) kinase aberrations, and various FGFR4-driven cancers. Tyra also leverages its proprietary SNAP platform, designed to accelerate structural drug design through an iterative molecular 'snapshot' approach. Founded in 2018, Tyra Biosciences maintains its headquarters in Carlsbad, California.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
USD31.93 -0.95 (-2.89%)
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Volume Profile
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Liquidity & share structure
Average Volume
990.7K
Beta
0.75
Float Shares
39.56M
Free Float %
73.7%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
+3.79% +9.83% +1.60% +29.30% +132.14% +37.66% +262.63% +174.58% +39.19% +39.19% +39.19%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
vs.
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Analyst Consensus (7 ratings, all time) Buy
Price Targets & DCF
Current price
31.93
Low 42.00 +31.5%
Consensus 50.50 +58.2%
Median 51.50 +61.3%
High 59.00 +84.8%
DCF (Unlevered) 1.18 -96.3%
DCF (Levered) 1.20 -96.2%

DCF figures are point estimates: small changes in growth or discount-rate assumptions move them materially. Read them as a reference, not a precise target.

Ratings Trend (MoM) 100% Bullish
Rating 2026-05 Change
Strong Buy 2 0
Buy 11 0
Hold 0 0
Sell 0 0
Strong Sell 0 0
Price Target Summary
Period # Analysts Avg Target
Last Month 1
54.00
+69.1%
Last Quarter 2
49.50
+55.0%
Last Year 8
47.00
+47.2%
All Time 15
37.87
+18.6%
Quality scores
Altman Z-Score
44.58
Safe zone
Piotroski F-Score
1 / 9
Weak
MOAT Score
3 / 10
No MOAT
Composite Rating
C-
Overall Score
1 / 5
Low
DCF Score
2 / 5
Medium
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
3 / 5
Medium
P/E Score
1 / 5
Low
P/Book Score
1 / 5
Low
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
  • EPS growth Biotechnology: +29.7%
    -33.1% Q1'26: -36.2% (vs Q1'25)
  • FCF margin FCF growth · Biotechnology: +16.2%
  • EBIT margin Biotechnology: +0.0%
  • ROIC Biotechnology: -16.1%
    -1,335.1% Q1'26: +0.0% (vs Q1'25)
  • Share dilution Biotechnology: -3.4%
    +4.2% Q1'26: +4.1% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    -0.05× Q1'26: -0.03× (vs Q1'25)
Valuation Multiples From To
DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (0.79) × ERP
WACC = 100% × Ke + 0% × Kd (4.1%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Intrinsic value (base): 1.18 Current price: 31.93
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2024
actual
Dec 2025
actual
Dec 2026
7 Rev. Ana.
11 EPS Ana.
Dec 2027
9 Rev. Ana.
8 EPS Ana.
Dec 2028
9 Rev. Ana.
9 EPS Ana.
Dec 2029
4 Rev. Ana.
3 EPS Ana.
Dec 2030
4 Rev. Ana.
3 EPS Ana.
Revenue
687.4K
687.4K – 687.4K
1.06M
1.06M – 1.06M
+53.9% YoY
10.37M
10.37M – 10.37M
+880.7% YoY
46.69M
46.69M – 46.69M
+350.0% YoY
235.58M
235.58M – 235.58M
+404.6% YoY
EBITDA
-103.66M
-119.40M
— – —
— – —
— – —
— – —
— – —
EBIT
-104.18M
-119.95M
— – —
— – —
— – —
— – —
— – —
Net Income
-86.48M
est: -89.21M (+3.1%)
-119.95M
est: -119.95M (+0.0%)
-152.43M
-156.58M – -120.67M
-27.1% YoY
-149.99M
-179.75M – -120.23M
+1.6% YoY
-203.17M
-203.93M – -66.40M
-35.5% YoY
-158.99M
-158.99M – -158.99M
+21.7% YoY
-58.39M
-58.39M – -58.39M
+63.3% YoY
SGA
24.10M
29.83M
— – —
— – —
— – —
— – —
— – —
EPS
-1.51
est: -1.55 (+2.8%)
-2.01
est: -1.98 (-1.6%)
-2.39
-2.63 – -2.02
-20.8% YoY
-2.65
-3.02 – -2.02
-10.9% YoY
-2.83
-3.42 – -1.11
-6.6% YoY
-2.67
-2.67 – -2.67
+5.6% YoY
-0.98
-0.98 – -0.98
+63.3% YoY
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-13 C- 1/5 2/5 1/5 1/5 3/5 1/5 1/5
2026-05-12 C- 1/5 2/5 1/5 1/5 3/5 1/5 1/5
2026-05-11 C- 1/5 2/5 1/5 1/5 3/5 1/5 1/5
2026-05-08 C- 1/5 2/5 1/5 1/5 3/5 1/5 1/5
2026-05-07 C- 1/5 2/5 1/5 1/5 3/5 1/5 1/5
2026-05-06 C- 1/5 2/5 1/5 1/5 3/5 1/5 1/5
2026-05-05 C- 1/5 2/5 1/5 1/5 3/5 1/5 1/5
2026-05-04 C- 1/5 2/5 1/5 1/5 3/5 1/5 1/5
2026-05-01 C- 1/5 2/5 1/5 1/5 3/5 1/5 1/5
2026-04-30 C- 1/5 2/5 1/5 1/5 3/5 1/5 1/5
2026-04-29 C- 1/5 2/5 1/5 1/5 3/5 1/5 1/5
2026-04-28 C- 1/5 2/5 1/5 1/5 3/5 1/5 1/5
2026-04-27 C- 1/5 2/5 1/5 1/5 3/5 1/5 1/5
2026-04-24 C- 1/5 3/5 1/5 1/5 2/5 1/5 1/5
2026-04-23 C- 1/5 3/5 1/5 1/5 2/5 1/5 1/5
2026-04-22 C- 1/5 3/5 1/5 1/5 2/5 1/5 1/5
2026-04-21 C- 1/5 3/5 1/5 1/5 2/5 1/5 1/5
2026-04-20 C- 1/5 3/5 1/5 1/5 2/5 1/5 1/5
2026-04-17 C- 1/5 3/5 1/5 1/5 2/5 1/5 1/5
2026-04-16 C- 1/5 3/5 1/5 1/5 2/5 1/5 1/5

Owner Earnings

Owner's Earnings (history)

Owner's Earnings history not available.

Owner alignment
Owner's Earnings TTM
OE per share TTM
Owner's Yield
Maintenance CapEx ratio
Maint CapEx / Avg PPE

Ownership Overview

Ownership breakdown
At a glance
Institutional holders
56
Total invested
289.20M
Insider transactions (90d)
5
Beneficial owners (>5%)
30
Beneficial owners (>5%)
# Reporting person Amount owned % of class Sole voting Shared voting Sole dispositive Shared dispositive Type Citizenship Filing date SEC filing
1 Peter Kolchinsky 7.24M 17.00% 7.24M 11.00 HC, IN 2021-09-27
2 RA Capital Management, L.P. 7.24M 17.00% 7.24M 11.00 IA, PN 2021-09-27
3 Boxer Asset Management Inc. 6.32M 15.10% 6.32M 6.32M CO 2022-06-16
4 Boxer Capital, LLC 6.32M 15.10% 6.32M 6.32M OO 2022-06-16
5 Joe Lewis 6.32M 15.10% 6.32M 6.32M IN 2022-06-16
6 RA Capital Healthcare Fund, L.P. 5.30M 12.50% 5.30M 10.00 PN Delaware 2021-09-27
7 Alta Partners NextGen Fund II Management, LLC 4.08M 9.60% 4.08M 10.00 OO Delaware 2021-09-27
8 Alta Partners NextGen Fund II, L.P. 4.08M 9.60% 4.08M 10.00 PN Delaware 2021-09-27
9 Peter Hudson 4.08M 9.60% 4.08M 10.00 IN United States of America 2021-09-27
10 Canaan Partners XI LLC 3.94M 9.50% 3.94M 3.94M OO 2022-02-08
11 Canaan XI L.P. 3.94M 9.50% 3.94M 3.94M PN 2022-02-08
12 Abigail P. Johnson 3.47M 8.41% 3.47M IN United States of America 2022-02-09
13 FMR LLC 3.47M 8.41% 199.9K 3.47M HC Delaware 2022-02-09
14 2. 2.52M 5.90% 2.52M IN Luxembourg 2021-09-27
15 BVF Inc. 2.47M 5.90% 2.47M CO Delaware 2022-03-24
16 BVF Partners L.P. 2.47M 5.90% 2.47M IA, PN Delaware 2022-03-24
17 Mark N. Lampert 2.47M 5.90% 2.47M IN Delaware 2022-03-24
18 BVF GP HOLDINGS LLC 2.32M 5.60% 2.32M OO Delaware 2022-03-24
19 BVF I GP LLC 1.35M 3.20% 1.35M OO Delaware 2022-03-24
20 Biotechnology Value Fund, L.P. 1.35M 3.20% 1.35M PN Delaware 2022-03-24
21 BVF II GP LLC 971.3K 2.30% 971.3K OO Delaware 2022-03-24
22 Biotechnology Value Fund II, L.P. 971.3K 2.30% 971.3K PN Delaware 2022-03-24
23 TCG Crossover Management, LLC 937.5K 2.20% 937.5K 937.5K IA Delaware, United States 2021-09-29
24 Canaan 2020+ Co-Investment L.P. — Series 7 473.4K 1.10% 473.4K 473.4K PN 2022-02-08
25 Canaan Partners 2020+ Co-Investment LLC 473.4K 1.10% 473.4K 473.4K OO 2022-02-08
26 Aaron I. Davis 288.1K 0.70% 288.1K 288.1K IN 2022-06-16
27 MVA Investors, LLC 288.1K 0.70% 288.1K 288.1K OO 2022-06-16
28 BVF Partners OS Ltd. 129.3K 1.00% 129.3K CO Delaware 2022-03-24
29 Biotechnology Value Trading Fund OS LP 129.3K 1.00% 129.3K PN Delaware 2022-03-24
30 Siddarth Subramony 1.2K 0.00% 1.2K 1.2K IN 2022-06-16

Institutional Activity (13F)

Institutional ownership trend From To
13F snapshot — 2026 Q1
Investors holding
56
-77 vs prev Q
New positions
19
Closed positions
96
Increased
36
Reduced
9
Put/Call ratio
0.00
Calls held
Puts held
Top institutional holders
# Investor Shares / Δ Mkt value / Δ Own% / Δ Weight% / Δ Avg px / Perf. Hold / Status
1 RA CAPITAL MANAGEMENT, L.P. 12.20M +— (+0.0%) 320.70M +150.0M (+87.9%) 20.44% -0.041 pp 3.29% +1.183 pp USD16.31 +61.2% 18 qtrs
2 NEXTECH INVEST, LTD. 4.06M +— (+0.0%) 106.63M +49.9M (+87.9%) 6.80% -0.014 pp 10.31% +1.671 pp USD9.30 +182.7% 4 qtrs
3 ALTA PARTNERS MANAGEMENT COMPANY, L.P. 3.82M -256.9K (-6.3%) 100.52M +43.4M (+76.1%) 6.41% -0.444 pp 97.03% +1.885 pp USD13.90 +89.1% 5 qtrs
4 COMMODORE CAPITAL LP 3.38M +— (+0.0%) 88.73M +41.5M (+87.9%) 5.66% -0.011 pp 5.91% +3.601 pp USD9.85 +166.9% 4 qtrs
5 CANAAN PARTNERS XI LLC 3.37M -233.8K (-6.5%) 88.71M +38.2M (+75.7%) 5.65% -0.404 pp 64.85% +15.775 pp USD14.07 +86.9% 17 qtrs
6 JANUS HENDERSON GROUP PLC 2.94M +60.6K (+2.1%) 77.08M +36.9M (+91.6%) 4.92% +0.092 pp 0.03% +0.016 pp USD15.93 +65.0% 6 qtrs
7 TCG CROSSOVER MANAGEMENT, LLC 2.90M +— (+0.0%) 76.19M +35.6M (+87.9%) 4.86% -0.010 pp 2.52% +0.527 pp USD10.10 +160.3% 17 qtrs
8 VESTAL POINT CAPITAL, LP 2.43M +— (+0.0%) 63.75M +29.8M (+87.9%) 4.06% -0.008 pp 2.17% +0.636 pp USD10.88 +141.6% 5 qtrs
9 BVF INC/IL 2.13M -1.5M (-41.7%) 55.94M +4.9M (+9.5%) 3.57% -2.563 pp 1.88% -0.187 pp USD16.22 +62.1% 18 qtrs
10 BLACKROCK, INC. 2.09M +216.9K (+11.6%) 54.85M +28.7M (+109.7%) 3.50% +0.357 pp 0.00% +0.001 pp USD21.59 +21.8% 6 qtrs
11 FARALLON CAPITAL MANAGEMENT LLC 2.07M +923.0K (+80.7%) 54.34M +38.3M (+239.6%) 3.46% +1.543 pp 0.26% +0.191 pp USD19.12 +37.5% 5 qtrs
12 VANGUARD GROUP INC 1.57M +52.6K (+3.5%) 41.35M +20.1M (+94.4%) 2.64% +0.083 pp 0.00% +0.000 pp USD14.54 +80.8% 17 qtrs
13 KYNAM CAPITAL MANAGEMENT, LP 1.56M -765.5K (-32.9%) 41.13M +8.5M (+26.2%) 2.62% -1.291 pp 2.63% +0.200 pp USD10.55 +149.2% 9 qtrs
14 5AM VENTURE MANAGEMENT, LLC 1.03M +90.0K (+9.6%) 27.06M +13.9M (+105.9%) 1.73% +0.148 pp 8.51% +3.694 pp USD16.04 +63.9% 10 qtrs
15 CALIGAN PARTNERS LP 944.3K +247.4K (+35.5%) 24.82M +15.1M (+154.6%) 1.58% +0.412 pp 2.04% +0.767 pp USD16.32 +61.1% 4 qtrs
16 POINT72 ASSET MANAGEMENT, L.P. 874.2K +592.2K (+210.0%) 22.98M +19.0M (+482.5%) 1.47% +0.991 pp 0.03% +0.019 pp USD21.24 +23.8% 5 qtrs
17 BALYASNY ASSET MANAGEMENT L.P. 818.3K -28.3K (-3.3%) 21.51M +9.7M (+81.6%) 1.37% -0.050 pp 0.03% +0.012 pp USD10.87 +141.9% 6 qtrs
18 STATE STREET CORP 749.5K +321.0K (+74.9%) 19.70M +13.7M (+228.7%) 1.26% +0.537 pp 0.00% +0.001 pp USD19.55 +34.5% 17 qtrs
19 MARSHALL WACE, LLP 711.9K +109.9K (+18.3%) 18.72M +10.3M (+122.2%) 1.19% +0.182 pp 0.02% +0.009 pp USD13.70 +91.9% 9 qtrs
20 GEODE CAPITAL MANAGEMENT, LLC 657.8K +60.3K (+10.1%) 17.30M +8.9M (+106.9%) 1.10% +0.099 pp 0.00% +0.001 pp USD15.39 +70.8% 17 qtrs
21 SIO CAPITAL MANAGEMENT, LLC 526.0K +11.1K (+2.1%) 13.83M +6.6M (+92.0%) 0.88% +0.017 pp 2.18% +0.352 pp USD12.00 +119.1% 8 qtrs
22 BOONE CAPITAL MANAGEMENT LLC 398.5K +398.5K (+100.0%) 10.48M +10.5M (+100.0%) 0.67% +0.668 pp 3.29% +3.288 pp USD26.29 +0.0% 1 qtrs NEW
23 EVERSEPT PARTNERS, LP 278.6K +5.9K (+2.1%) 7.32M +3.5M (+92.0%) 0.47% +0.009 pp 0.37% +0.106 pp USD14.25 +84.5% 2 qtrs
24 BOOTHBAY FUND MANAGEMENT, LLC 221.2K +34.5K (+18.5%) 5.81M +3.2M (+122.7%) 0.37% +0.057 pp 0.09% +0.049 pp USD15.91 +65.2% 2 qtrs
25 LOGOS GLOBAL MANAGEMENT LP 210.0K +210.0K (+100.0%) 5.52M +5.5M (+100.0%) 0.35% +0.352 pp 0.33% +0.334 pp USD26.29 +0.0% 1 qtrs NEW
26 NORTHERN TRUST CORP 201.0K -7.5K (-3.6%) 5.28M +2.4M (+81.1%) 0.34% -0.013 pp 0.00% +0.000 pp USD16.84 +56.1% 17 qtrs
27 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 199.4K -2.2K (-1.1%) 5.24M +2.4M (+85.9%) 0.33% -0.004 pp 0.00% +0.000 pp USD14.31 +83.7% 17 qtrs
28 GOLDMAN SACHS GROUP INC 182.4K +82.2K (+82.1%) 4.79M +3.4M (+242.2%) 0.31% +0.138 pp 0.00% +0.000 pp USD19.64 +33.9% 8 qtrs
29 RAYMOND JAMES FINANCIAL INC 170.0K +43.7K (+34.5%) 4.47M +2.7M (+152.8%) 0.29% +0.073 pp 0.00% +0.001 pp USD16.89 +55.7% 5 qtrs
30 BNP PARIBAS ASSET MANAGEMENT HOLDING S.A. 129.8K +129.8K (+100.0%) 3.41M +3.4M (+100.0%) 0.22% +0.218 pp 0.00% +0.004 pp USD26.29 +0.0% 1 qtrs NEW
31 JACOBS LEVY EQUITY MANAGEMENT, INC 129.8K -121.8K (-48.4%) 3.41M -108.1K (-3.1%) 0.22% -0.205 pp 0.01% -0.001 pp USD12.21 +115.3% 5 qtrs
32 INVESCO LTD. 129.4K +113.9K (+734.5%) 3.40M +3.2M (+1,468.2%) 0.22% +0.191 pp 0.00% +0.001 pp USD24.82 +5.9% 2 qtrs
33 SOLEUS CAPITAL MANAGEMENT, L.P. 125.0K +125.0K (+100.0%) 3.29M +3.3M (+100.0%) 0.21% +0.210 pp 0.12% +0.121 pp USD26.29 +0.0% 1 qtrs NEW
34 BNP PARIBAS ARBITRAGE, SNC 120.3K -8.6K (-6.7%) 3.16M +1.4M (+75.4%) 0.20% -0.015 pp 0.00% +0.001 pp USD10.65 +146.9% 5 qtrs
35 MORGAN STANLEY 118.9K -203.2K (-63.1%) 3.13M -1.4M (-30.6%) 0.20% -0.342 pp 0.00% 0.000 pp USD10.61 +147.8% 17 qtrs
36 MILLENNIUM MANAGEMENT LLC 114.4K -29.6K (-20.6%) 3.01M +992.5K (+49.3%) 0.19% -0.050 pp 0.00% +0.000 pp USD13.11 +100.5% 6 qtrs
37 TWO SIGMA INVESTMENTS, LP 107.0K -92.4K (-46.3%) 2.81M +23.5K (+0.8%) 0.18% -0.156 pp 0.00% 0.000 pp USD13.34 +97.1% 8 qtrs
38 WELLINGTON MANAGEMENT GROUP LLP 104.3K +21.4K (+25.9%) 2.74M +1.6M (+136.5%) 0.17% +0.036 pp 0.00% +0.000 pp USD16.73 +57.1% 18 qtrs
39 DIMENSIONAL FUND ADVISORS LP 95.6K +56.0K (+141.0%) 2.51M +2.0M (+353.0%) 0.16% +0.094 pp 0.00% +0.000 pp USD21.72 +21.0% 11 qtrs
40 INVESTMENT COUNSEL CO OF NEVADA 85.0K +— (+0.0%) 2.24M +1.0M (+87.9%) 0.14% 0.000 pp 4.80% +2.380 pp USD13.90 +89.1% 5 qtrs
41 OPPENHEIMER & CO INC 84.7K +2.5K (+3.0%) 2.23M +1.1M (+93.6%) 0.14% +0.004 pp 0.03% +0.018 pp USD17.40 +51.1% 8 qtrs
42 79.6K +79.6K (+100.0%) 2.09M +2.1M (+100.0%) 0.13% +0.133 pp 1.59% +1.591 pp USD26.29 +0.0% 1 qtrs NEW
43 BARCLAYS PLC 76.3K +38.7K (+102.8%) 2.01M +1.1M (+126.8%) 0.13% +0.065 pp 0.00% +0.000 pp USD21.48 +22.4% 16 qtrs
44 JPMORGAN CHASE & CO 71.2K -3.1K (-4.1%) 1.87M +832.7K (+80.2%) 0.12% -0.005 pp 0.00% +0.000 pp USD14.30 +83.8% 17 qtrs
45 BANK OF NEW YORK MELLON CORP 60.9K +3.7K (+6.5%) 1.60M +801.4K (+100.2%) 0.10% +0.006 pp 0.00% +0.000 pp USD13.17 +99.6% 17 qtrs
46 TWO SIGMA ADVISERS, LP 58.9K -54.3K (-48.0%) 1.55M -35.2K (-2.2%) 0.10% -0.091 pp 0.00% 0.000 pp USD10.97 +139.7% 5 qtrs
47 UBS GROUP AG 58.9K -288.0 (-0.5%) 1.55M +719.9K (+87.0%) 0.10% -0.001 pp 0.00% +0.000 pp USD14.64 +79.6% 17 qtrs
48 SUPERSTRING CAPITAL MANAGEMENT LP 58.7K +58.7K (+100.0%) 1.54M +1.5M (+100.0%) 0.10% +0.098 pp 0.83% +0.826 pp USD26.29 +0.0% 1 qtrs NEW
49 SUSQUEHANNA INTERNATIONAL GROUP, LLP 55.1K +55.1K (+100.0%) 1.45M +1.4M (+100.0%) 0.09% +0.092 pp 0.00% +0.000 pp USD26.29 +0.0% 4 qtrs
50 AMERIPRISE FINANCIAL INC 54.6K -32.5K (-37.3%) 1.44M +217.5K (+17.8%) 0.09% -0.055 pp 0.00% +0.000 pp USD9.90 +165.6% 3 qtrs
51 SQUAREPOINT OPS LLC 54.4K +42.2K (+345.6%) 1.43M +1.3M (+737.3%) 0.09% +0.071 pp 0.00% +0.001 pp USD22.54 +16.6% 5 qtrs
52 SUSQUEHANNA PORTFOLIO STRATEGIES, LLC 48.6K +— (+0.0%) 1.28M +598.3K (+87.9%) 0.08% 0.000 pp 0.02% +0.009 pp USD9.57 +174.7% 3 qtrs
53 NUVEEN, LLC 47.3K -33.1K (-41.1%) 1.24M +119.4K (+10.6%) 0.08% -0.056 pp 0.00% +0.000 pp USD9.40 +179.7% 4 qtrs
54 ALGERT GLOBAL LLC 46.9K +46.9K (+100.0%) 1.23M +1.2M (+100.0%) 0.08% +0.079 pp 0.02% +0.019 pp USD26.29 +0.0% 1 qtrs NEW
55 AMERICAN CENTURY COMPANIES INC 46.2K +7.8K (+20.3%) 1.22M +677.9K (+126.2%) 0.08% +0.013 pp 0.00% +0.000 pp USD16.88 +55.7% 9 qtrs
56 Y-INTERCEPT (HONG KONG) LTD 45.9K +45.9K (+100.0%) 1.21M +1.2M (+100.0%) 0.08% +0.077 pp 0.03% +0.027 pp USD26.29 +0.0% 1 qtrs NEW
57 ALPS ADVISORS INC 43.8K +19.1K (+77.4%) 1.15M +806.7K (+233.4%) 0.07% +0.032 pp 0.01% +0.005 pp USD16.87 +55.8% 3 qtrs
58 EXODUSPOINT CAPITAL MANAGEMENT, LP 42.8K +42.8K (+100.0%) 1.12M +1.1M (+100.0%) 0.07% +0.072 pp 0.01% +0.009 pp USD26.29 +0.0% 4 qtrs
59 PDT PARTNERS, LLC 42.3K -1.0K (-2.4%) 1.11M +505.7K (+83.5%) 0.07% -0.002 pp 0.07% +0.034 pp USD9.57 +174.7% 8 qtrs
60 STATE OF WISCONSIN INVESTMENT BOARD 39.0K +9.4K (+31.6%) 1.03M +611.1K (+147.3%) 0.07% +0.016 pp 0.00% +0.001 pp USD17.19 +52.9% 7 qtrs
61 RHUMBLINE ADVISERS 38.8K -1.8K (-4.5%) 1.02M +451.3K (+79.4%) 0.07% -0.003 pp 0.00% +0.000 pp USD10.83 +142.8% 16 qtrs
62 BANK OF AMERICA CORP /DE/ 38.3K -96.0K (-71.5%) 1.01M -872.0K (-46.4%) 0.06% -0.161 pp 0.00% 0.000 pp USD10.51 +150.1% 18 qtrs
63 HIGHVISTA STRATEGIES LLC 35.1K -30.7K (-46.7%) 922.4K +1.7K (+0.2%) 0.06% -0.052 pp 0.24% +0.012 pp USD14.71 +78.7% 7 qtrs
64 ALLIANCEBERNSTEIN L.P. 32.0K -1.3K (-3.8%) 841.0K +375.7K (+80.7%) 0.05% -0.002 pp 0.00% +0.000 pp USD13.37 +96.6% 7 qtrs
65 XTX TOPCO LTD 30.4K -3.3K (-9.8%) 799.6K +328.1K (+69.6%) 0.05% -0.006 pp 0.02% -0.004 pp USD9.57 +174.7% 3 qtrs
66 VOYA INVESTMENT MANAGEMENT LLC 29.9K +29.9K (+100.0%) 785.7K +785.7K (+100.0%) 0.05% +0.050 pp 0.00% +0.001 pp USD26.29 +0.0% 1 qtrs NEW
67 WELLS FARGO & COMPANY/MN 29.0K +10.6K (+57.3%) 763.7K +505.3K (+195.6%) 0.05% +0.018 pp 0.00% +0.000 pp USD18.06 +45.6% 12 qtrs
68 CANADA PENSION PLAN INVESTMENT BOARD 28.9K +28.9K (+100.0%) 759.8K +759.8K (+100.0%) 0.05% +0.048 pp 0.00% +0.001 pp USD26.29 +0.0% 1 qtrs NEW
69 FISHER ASSET MANAGEMENT, LLC 28.8K +28.8K (+100.0%) 757.2K +757.2K (+100.0%) 0.05% +0.048 pp 0.00% +0.000 pp USD26.29 +0.0% 1 qtrs NEW
70 AQR CAPITAL MANAGEMENT LLC 28.6K +562.0 (+2.0%) 752.7K +360.0K (+91.7%) 0.05% +0.001 pp 0.00% +0.000 pp USD9.90 +165.6% 3 qtrs
71 AUOUR INVESTMENTS LLC 21.0K +— (+0.0%) 552.6K +258.5K (+87.9%) 0.04% 0.000 pp 0.18% +0.080 pp USD17.03 +54.4% 11 qtrs
72 CREATIVE PLANNING 19.6K +19.6K (+100.0%) 515.4K +515.4K (+100.0%) 0.03% +0.033 pp 0.00% +0.000 pp USD26.29 +0.0% 1 qtrs NEW
73 VICTORY CAPITAL MANAGEMENT INC 18.8K +— (+0.0%) 494.0K +231.1K (+87.9%) 0.03% 0.000 pp 0.00% +0.000 pp USD14.64 +79.6% 12 qtrs
74 PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO 18.5K -6.4K (-25.7%) 487.5K +138.3K (+39.6%) 0.03% -0.011 pp 0.00% +0.000 pp USD10.71 +145.5% 3 qtrs
75 DEUTSCHE BANK AG\ 16.4K +894.0 (+5.8%) 430.6K +213.9K (+98.8%) 0.03% +0.001 pp 0.00% +0.000 pp USD16.58 +58.6% 17 qtrs
76 RAFFERTY ASSET MANAGEMENT, LLC 15.5K +15.5K (+100.0%) 406.3K +406.3K (+100.0%) 0.03% +0.026 pp 0.00% +0.001 pp USD26.29 +0.0% 1 qtrs NEW
77 METLIFE INVESTMENT MANAGEMENT, LLC 15.4K +725.0 (+5.0%) 403.7K +199.0K (+97.2%) 0.03% +0.001 pp 0.00% +0.001 pp USD15.88 +65.6% 12 qtrs
78 PRICE T ROWE ASSOCIATES INC /MD/ 14.4K +1.6K (+12.7%) 380.0K +200.0K (+111.1%) 0.02% +0.003 pp 0.00% +0.000 pp USD11.70 +124.7% 3 qtrs
79 RUSSELL INVESTMENTS GROUP, LTD. 13.0K +255.0 (+2.0%) 341.7K +163.4K (+91.7%) 0.02% +0.000 pp 0.00% +0.000 pp USD14.16 +85.7% 11 qtrs
80 FRANKLIN RESOURCES INC 13.0K +13.0K (+100.0%) 341.0K +341.0K (+100.0%) 0.02% +0.022 pp 0.00% +0.000 pp USD26.29 +0.0% 1 qtrs NEW
81 MIRAE ASSET GLOBAL ETFS HOLDINGS LTD. 12.9K +1.6K (+14.1%) 338.6K +180.3K (+113.9%) 0.02% +0.003 pp 0.00% +0.000 pp USD19.30 +36.2% 7 qtrs
82 FMR LLC 12.6K +34.0 (+0.3%) 330.3K +155.0K (+88.4%) 0.02% +0.000 pp 0.00% +0.000 pp USD15.99 +64.4% 18 qtrs
83 CITADEL ADVISORS LLC 12.5K -11.0K (-46.8%) 328.6K -140.0 (0.0%) 0.02% -0.019 pp 0.00% +0.000 pp USD13.99 +87.9% 8 qtrs
84 VIRTUS INVESTMENT ADVISERS, INC. 11.8K +741.0 (+6.7%) 309.1K +155.0K (+100.6%) 0.02% +0.001 pp 0.08% +0.040 pp USD11.13 +136.2% 4 qtrs
85 BANK OF NOVA SCOTIA 11.1K +11.1K (+100.0%) 291.8K +291.8K (+100.0%) 0.02% +0.019 pp 0.00% +0.000 pp USD26.29 +0.0% 1 qtrs NEW
86 BAKER BROS. ADVISORS LP 10.6K +— (+0.0%) 278.9K +130.5K (+87.9%) 0.02% +0.000 pp 0.00% +0.001 pp USD13.85 +89.8% 9 qtrs
87 INTECH INVESTMENT MANAGEMENT LLC 9.8K -1.6K (-14.0%) 257.7K +98.2K (+61.5%) 0.02% -0.003 pp 0.00% +0.001 pp USD9.39 +180.0% 4 qtrs
88 CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD. 8.7K -645.0 (-6.9%) 228.6K +97.9K (+74.9%) 0.01% -0.001 pp 0.02% +0.007 pp USD13.68 +92.2% 5 qtrs
89 MANUFACTURERS LIFE INSURANCE COMPANY, THE 8.4K +8.4K (+100.0%) 219.7K +219.7K (+100.0%) 0.01% +0.014 pp 0.00% +0.000 pp USD26.29 +0.0% 1 qtrs NEW
90 NEW YORK STATE COMMON RETIREMENT FUND 7.4K +— (+0.0%) 195.2K +91.3K (+87.9%) 0.01% +0.000 pp 0.00% +0.000 pp USD16.11 +63.2% 16 qtrs
91 POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY 6.4K +— (+0.0%) 169.3K +79.2K (+87.9%) 0.01% +0.000 pp 0.00% +0.001 pp USD13.92 +88.9% 5 qtrs
92 CITIGROUP INC 3.8K +2.1K (+123.6%) 100.3K +76.5K (+320.2%) 0.01% +0.004 pp 0.00% +0.000 pp USD23.62 +11.3% 18 qtrs
93 BELLEVUE GROUP AG 3.1K +3.1K (+100.0%) 82.6K +82.6K (+100.0%) 0.01% +0.005 pp 0.00% +0.002 pp USD26.29 +0.0% 1 qtrs NEW
94 CAITONG INTERNATIONAL ASSET MANAGEMENT CO., LTD 3.0K +3.0K (+100.0%) 78.8K +78.8K (+100.0%) 0.01% +0.005 pp 0.02% +0.019 pp USD26.29 +0.0% 4 qtrs
95 MIRAE ASSET GLOBAL INVESTMENTS CO., LTD. 2.6K +534.0 (+25.9%) 68.2K +39.4K (+136.6%) 0.00% +0.001 pp 0.00% +0.000 pp USD15.83 +66.1% 5 qtrs
Ownership breakdown by holder

ETF Ownership

Top ETFs holding this stock Held by 94 ETFs in our universe
# ETF Weight Est. AUM exposure TER
1 Tema Oncology ETF CANC 1.04% 1.48M 0.75%
2 ALPS Medical Breakthroughs ETF SBIO 1.00% 2.12M 0.50%
3 Virtus Biotech Clinical Trials ETF BBC 0.75% 429.9K 0.65%
4 Global X - S&P Biotech ETF CURE.AX 0.42% 152.2K 0.45%
5 State Street SPDR S&P Biotech ETF XBI 0.42% 45.72M 0.35%
6 VictoryShares US Small Mid Cap Value Momentum ETF USVM 0.20% 3.44M 0.29%
7 Vanguard U.S. Momentum Factor ETF VFMO 0.16% 2.78M 0.13%
8 Invesco NASDAQ Biotech UCITS ETF SBIO.L 0.13% 619.8K 0.40%
9 Invesco Nasdaq Biotechnology ETF IBBQ 0.13% 100.0K 0.19%
10 iShares Nasdaq US Biotechnology UCITS ETF BTEE.L 0.13% 98.1K 0.35%

Insider Activity

Insider Activity — Latest Quarter
Ratio by transactions
0.00
Bearish
Buys
11
Sells
0
Shares acquired
687.0K
Shares disposed
Cash buys
Cash sales
Net activity
+687,041
Insider buys vs sells (history) From To
Recent insider transactions From To
Date Person Role Transaction A/D Security Shares Price Value Owned after D/I Filing
2026-05-05 Warner Douglas J Officer A-Award A Stock Option (Right to Buy) 85,000 33.93 2.88M 85,000 D
2026-05-05 Rueb Yuliya Officer A-Award A Common Stock 8,333 0.00 43,354 D
2026-05-05 Harris Todd Director / Officer A-Award A Common Stock 79,000 0.00 1,437,631 D
2026-05-05 Fuhrman Alan Officer A-Award A Stock Option (Right to Buy) 67,000 33.93 2.27M 67,000 D
2026-05-05 Ashar Bhavesh Officer A-Award A Stock Option (Right to Buy) 50,295 33.93 1.71M 50,295 D
2026-04-16 Dable Habib J Director No securities are beneficially owned. 0 0.00 0 D
2026-04-01 Rueb Yuliya Officer Stock Option (Right to Buy) 9,034 6.50 58.7K 0 D
2026-03-26 KAPLAN GILLA Director M-Exempt D Common Stock 53,172 2.25 119.6K 81,403 D
2026-03-25 KAPLAN GILLA Director M-Exempt D Stock Option (Right to Buy) 14,295 2.25 32.2K 53,172 D
2026-03-13 Harris Todd Director / Officer A-Award A Common Stock 1,463 9.13 13.4K 1,358,631 D
2026-03-13 Fuhrman Alan Officer A-Award A Common Stock 1,376 9.13 12.6K 16,164 D
2026-02-12 Bensen Daniel Officer S-Sale D Common Stock 2,128 31.50 67.0K 152,853 D
2026-01-12 Bensen Daniel Officer S-Sale D Common Stock 6,983 28.44 198.6K 155,998 D
2025-12-19 MORE ROBERT J Director S-Sale D Common Stock 10,000 25.00 250.0K 3,823,425 I
2025-12-12 Bensen Daniel Officer S-Sale D Common Stock 8,000 22.64 181.2K 162,981 D
2025-12-01 Ashar Bhavesh Officer A-Award A Stock Option (Right to Buy) 300,000 20.81 6.24M 300,000 D
2025-11-21 MORE ROBERT J Director S-Sale D Common Stock 246,871 20.25 5.00M 3,833,425 I
2025-11-19 Bensen Daniel Officer S-Sale D Common Stock 49,956 16.32 815.3K 170,981 D
2025-11-18 Bensen Daniel Officer S-Sale D Common Stock 75,633 16.07 1.22M 220,937 D
2025-11-17 Bensen Daniel Officer S-Sale D Common Stock 18,572 16.11 299.2K 298,070 D
2025-11-14 Bensen Daniel Officer S-Sale D Common Stock 110,228 16.02 1.77M 316,642 D
2025-11-13 Bensen Daniel Officer S-Sale D Common Stock 1,111 16.00 17.8K 426,870 D
2025-09-15 Fuhrman Alan Officer A-Award A Common Stock 701 9.13 6.4K 14,788 D
2025-08-07 Warner Douglas J Officer A-Award A Stock Option (Right to Buy) 200,000 10.75 2.15M 200,000 D
2025-08-07 Harris Todd Director / Officer A-Award A Stock Option (Right to Buy) 570,000 10.75 6.13M 570,000 D
2025-08-07 Fuhrman Alan Officer A-Award A Stock Option (Right to Buy) 170,000 10.75 1.83M 170,000 D
2025-08-07 Bensen Daniel Officer A-Award A Stock Option (Right to Buy) 170,000 10.75 1.83M 170,000 D
2025-06-18 KAPLAN GILLA Director S-Sale D Common Stock 9,568 9.78 93.6K 28,231 D
2025-06-17 KAPLAN GILLA Director S-Sale D Common Stock 10 10.35 103.50 37,799 D
2025-06-16 RA CAPITAL MANAGEMENT, L.P. Director / 10% Owner P-Purchase A Common Stock 11,813 10.13 119.7K 10,259,291 I
2025-06-16 KAPLAN GILLA Director S-Sale D Common Stock 6,814 10.38 70.7K 37,809 D
2025-06-13 RA CAPITAL MANAGEMENT, L.P. Director / 10% Owner P-Purchase A Common Stock 120,167 10.20 1.23M 10,247,478 I
2025-06-13 KAPLAN GILLA Director S-Sale D Common Stock 15,000 10.31 154.6K 44,623 D
2025-06-12 RA CAPITAL MANAGEMENT, L.P. Director / 10% Owner P-Purchase A Common Stock 31,307 10.20 319.3K 10,127,311 I
2025-06-12 KAPLAN GILLA Director S-Sale D Common Stock 30,000 10.31 309.3K 59,623 D
2025-06-09 RA CAPITAL MANAGEMENT, L.P. Director / 10% Owner P-Purchase A Common Stock 186,850 10.19 1.90M 10,096,004 I
2025-06-05 RA CAPITAL MANAGEMENT, L.P. Director / 10% Owner P-Purchase A Common Stock 213,334 10.04 2.14M 9,909,154 I
2025-06-04 RA CAPITAL MANAGEMENT, L.P. Director / 10% Owner P-Purchase A Common Stock 997,864 9.63 9.61M 9,695,820 I
2025-05-29 Verjee Rehan Director A-Award A Stock Option (Right to Buy) 22,200 9.25 205.4K 22,200 D
2025-05-29 Simson Jake Director A-Award A Stock Option (Right to Buy) 22,200 9.25 205.4K 22,200 D
2025-05-29 Rothenberg Stephen Michael Director A-Award A Stock Option (Right to Buy) 22,200 9.25 205.4K 22,200 D
2025-05-29 RA CAPITAL MANAGEMENT, L.P. Director / 10% Owner A-Award A Stock Option (Right to Buy) 22,200 9.25 205.4K 22,200 I
2025-05-29 Moran Susan Director A-Award A Stock Option (Right to Buy) 22,200 9.25 205.4K 22,200 D
2025-05-29 MORE ROBERT J Director A-Award A Stock Option (Right to Buy) 22,200 9.25 205.4K 22,200 D
2025-05-29 KAPLAN GILLA Director A-Award A Stock Option (Right to Buy) 22,200 9.25 205.4K 22,200 D
2025-03-14 Harris Todd Director / Officer A-Award A Common Stock 1,241 9.78 12.1K 1,357,168 D
2025-03-14 Fuhrman Alan Officer A-Award A Common Stock 1,238 9.78 12.1K 14,087 D
2025-02-05 Kjellson Nina S Director S-Sale D Common Stock 1,890 13.76 26.0K 3,700,705 I
2025-01-29 Gulfo Adele M. Director A-Award A Common Stock (Right to Buy) 37,200 14.65 545.0K 37,200 D
2025-01-23 Kjellson Nina S Director S-Sale D Common Stock 4,825 16.26 78.5K 3,702,595 I
2025-01-21 Kjellson Nina S Director S-Sale D Common Stock 3,993 16.36 65.3K 3,707,420 I
2025-01-17 Kjellson Nina S Director S-Sale D Common Stock 12,808 16.40 210.1K 3,711,413 I
2025-01-16 Kjellson Nina S Director S-Sale D Common Stock 6,944 16.29 113.1K 3,724,221 I
2024-11-25 Kjellson Nina S Director S-Sale D Common Stock 4,706 16.84 79.2K 3,731,165 I
2024-11-08 RA CAPITAL MANAGEMENT, L.P. Director / 10% Owner P-Purchase A Common Stock 1,220,681 16.25 19.84M 8,697,956 I
2024-11-07 Kjellson Nina S Director S-Sale D Common Stock 19,720 17.32 341.5K 3,735,871 I
2024-11-06 Kjellson Nina S Director S-Sale D Common Stock 46,856 17.18 804.8K 3,755,591 I
2024-11-05 Kjellson Nina S Director S-Sale D Common Stock 9,367 16.77 157.1K 3,802,447 I
2024-11-04 Kjellson Nina S Director S-Sale D Common Stock 960 17.01 16.3K 3,811,814 I
2024-11-01 Kjellson Nina S Director S-Sale D Commmon Stock 604 17.16 10.4K 3,812,774 I
2024-10-31 Kjellson Nina S Director S-Sale D Common Stock 89,390 16.46 1.47M 3,837,316 I
2024-10-30 Kjellson Nina S Director S-Sale D Common Stock 1,189 16.17 19.2K 472,207 I
2024-10-30 Fuhrman Alan Officer P-Purchase A Common Stock 9,500 16.00 152.0K 12,849 D
2024-10-21 Harris Todd Director / Officer S-Sale D Common Stock 5,896 27.32 161.1K 1,369,115 D
2024-10-18 RA CAPITAL MANAGEMENT, L.P. Director / 10% Owner J-Other A Pre-Funded Warrants (Right to Buy) 2,358,457 0.00 2.4K 1,000,000 I
2024-10-18 Harris Todd Director / Officer S-Sale D Common Stock 43,636 27.01 1.18M 1,375,011 D
2024-10-18 Boxer Capital Management, LLC Other D-Return D Common Stock 2,000,000 0.00 4,448,359 I
2024-10-17 Harris Todd Director / Officer S-Sale D Common Stock 200 26.37 5.3K 1,418,647 D
2024-10-16 Harris Todd Director / Officer S-Sale D Common Stock 4,900 25.22 123.6K 1,462,438 D
2024-10-15 Harris Todd Director / Officer S-Sale D Common Stock 10,035 24.31 244.0K 1,467,338 D
2024-10-10 Boxer Capital Management, LLC Other Warrant (right to purchase) 705,280 13.01 9.17M 0 I
2024-09-30 Harris Todd Director / Officer S-Sale D Common Stock 500 24.00 12.0K 1,477,373 D
2024-09-25 Harris Todd Director / Officer S-Sale D Common Stock 600 24.01 14.4K 1,477,873 D
2024-09-24 Harris Todd Director / Officer S-Sale D Common Stock 1,055 24.02 25.3K 1,478,473 D
2024-09-23 Harris Todd Director / Officer S-Sale D Common Stock 10,092 24.13 243.5K 1,479,528 D
2024-09-20 Harris Todd Director / Officer S-Sale D Common Stock 7,109 24.19 172.0K 1,489,620 D
2024-09-19 Harris Todd Director / Officer S-Sale D Common Stock 5,671 24.30 137.8K 1,496,756 D
2024-09-18 Harris Todd Director / Officer S-Sale D Common Stock 3,500 24.00 84.0K 1,502,427 D
2024-09-13 Harris Todd Director / Officer A-Award A Common Stock 1,350 6.58 8.9K 1,505,927
2024-09-13 Fuhrman Alan Officer A-Award A Common Stock 954 12.48 11.9K 3,349
2024-09-09 Warner Douglas J Officer A-Award A Stock Option (Right to Buy) 260,000 21.51 5.59M 260,000
2024-08-14 Harris Todd Director / Officer A-Award A Stock Option (Right to Buy) 390,000 21.57 8.41M 390,000
2024-08-14 Fuhrman Alan Officer A-Award A Stock Option (Right to Buy) 115,000 21.57 2.48M 115,000
2024-08-14 Bensen Daniel Officer A-Award A Stock Option (Right to Buy) 115,000 21.57 2.48M 115,000
2024-06-13 KAPLAN GILLA Director M-Exempt A Common Stock 61,392 0.61 37.4K 89,623
2024-06-10 Bensen Daniel Officer S-Sale D Common Stock 3,502 20.00 70.0K 427,981
2024-06-07 Bensen Daniel Officer S-Sale D Common Stock 200 20.00 4.0K 431,483
2024-05-29 Verjee Rehan Director A-Award A Stock Option (Right to Buy) 18,600 15.94 296.5K 18,600
2024-05-29 Subramony Siddarth Director / 10% Owner A-Award A Stock Option (Right to Buy) 18,600 15.94 296.5K 18,600
2024-05-29 Simson Jake Director A-Award A Stock Option (Right to Buy) 18,600 15.94 296.5K 18,600
2024-05-29 RA CAPITAL MANAGEMENT, L.P. Director / 10% Owner A-Award A Stock Option (right to buy) 18,600 15.94 296.5K 18,600
2024-05-29 MORE ROBERT J Director A-Award A Stock Option (Right to Buy) 18,600 15.94 296.5K 18,600
2024-05-29 Kjellson Nina S Director A-Award A Stock Option (Right to Buy) 18,600 15.94 296.5K 18,600
2024-05-29 KAPLAN GILLA Director A-Award A Stock Option (Right to Buy) 18,600 15.94 296.5K 18,600
2024-05-07 Rothenberg Stephen Michael Director A-Award A Common Stock (Right to Buy) 37,200 17.94 667.4K 37,200
2024-05-07 Moran Susan Director A-Award A Common Stock (Right to Buy) 37,200 17.94 667.4K 37,200
2024-03-15 Tada Hiroomi Officer A-Award A Common Stock 1,968 6.58 12.9K 86,435
2024-03-15 Harris Todd Director / Officer A-Award A Common Stock 1,880 6.58 12.4K 1,504,577
2024-03-15 Fuhrman Alan Officer A-Award A Common Stock 932 12.48 11.6K 2,395
2024-03-11 Bensen Daniel Officer S-Sale D Common Stock 200 20.00 4.0K 431,683
2024-03-07 Bensen Daniel Officer S-Sale D Common Stock 68 20.00 1.4K 431,883
2024-03-06 Bensen Daniel Officer S-Sale D Common Stock 1,733 20.09 34.8K 431,951
2024-03-05 Bensen Daniel Officer S-Sale D Common Stock 1,189 20.02 23.8K 433,684
2024-03-04 Bensen Daniel Officer S-Sale D Common Stock 5,063 20.08 101.7K 434,873
2024-03-01 Bensen Daniel Officer S-Sale D Common Stock 2,900 20.04 58.1K 439,936
2024-02-29 Bensen Daniel Officer S-Sale D Common Stock 2,050 20.00 41.0K 442,836
2024-02-28 Bensen Daniel Officer S-Sale D Common Stock 5,849 20.13 117.7K 444,886
2024-02-27 Bensen Daniel Officer S-Sale D Common Stock 745 20.00 14.9K 450,735
2024-02-12 Bensen Daniel Officer S-Sale D Common Stock 1,501 20.00 30.0K 451,480
2024-02-07 Bensen Daniel Officer S-Sale D Common Stock 9,587 18.09 173.5K 452,981
2024-02-06 RA CAPITAL MANAGEMENT, L.P. Director / 10% Owner A-Award A Common Stock 3,180,155 13.01 41.37M 8,477,275
2024-02-06 Boxer Capital, LLC Other A-Award A Warrant (right to purchase) 705,280 0.00 705.28 705,280
2024-02-06 Bensen Daniel Officer S-Sale D Common Stock 15,413 18.09 278.8K 462,568
2024-02-05 Harris Todd Director / Officer S-Sale D Common Stock 13,817 16.97 234.4K 1,502,697
2024-02-02 Harris Todd Director / Officer S-Sale D Common Stock 7,187 17.04 122.5K 1,516,514
2024-02-02 Bensen Daniel Officer M-Exempt D Stock Option (Right to Buy) 25,393 0.61 15.5K 108,110
2023-09-15 Tada Hiroomi Officer A-Award A Common Stock 1,337 6.58 8.8K 84,467
2023-09-15 Harris Todd Director / Officer A-Award A Common Stock 1,421 6.58 9.3K 1,602,697
2023-09-15 Fuhrman Alan Officer A-Award A Common Stock 1,463 12.50 18.3K 1,463
2023-07-28 Tada Hiroomi Officer A-Award A Stock Option (Right to Buy) 115,000 14.35 1.65M 115,000
2023-07-28 Harris Todd Director / Officer A-Award A Stock Option (Right to Buy) 330,000 14.35 4.74M 330,000
2023-07-28 Fuhrman Alan Officer A-Award A Stock Option (Right to Buy) 62,685 14.35 899.5K 62,685
2023-07-28 Bensen Daniel Officer A-Award A Stock Option (Right to Buy) 110,000 14.35 1.58M 110,000
2023-07-21 Bensen Daniel Officer M-Exempt A Common Stock 3,900 0.61 2.4K 531,881
2023-07-19 Bensen Daniel Officer M-Exempt D Stock Option (Right to Buy) 207 0.61 126.27 137,403
2023-07-17 Bensen Daniel Officer S-Sale D Common Stock 1,900 16.03 30.5K 527,981
2023-07-13 Bensen Daniel Officer M-Exempt A Common Stock 500 0.61 305.00 528,481
2023-07-12 Bensen Daniel Officer M-Exempt A Common Stock 201 0.61 122.61 528,182
2023-07-11 Bensen Daniel Officer M-Exempt D Stock Option (Right to Buy) 201 0.61 122.61 140,010
2023-07-10 Bensen Daniel Officer M-Exempt D Stock Option (Right to Buy) 1,202 0.61 733.22 140,711
2023-07-03 Bensen Daniel Officer M-Exempt A Common Stock 4,265 0.61 2.6K 532,246
2023-06-30 Bensen Daniel Officer M-Exempt A Common Stock 18,819 0.61 11.5K 546,800
2023-06-29 Bensen Daniel Officer M-Exempt A Common Stock 17,281 0.61 10.5K 545,262
2023-06-28 Bensen Daniel Officer M-Exempt A Common Stock 13,524 0.61 8.2K 541,505
2023-06-27 Bensen Daniel Officer M-Exempt A Common Stock 16,028 0.61 9.8K 544,009
2023-06-26 Bensen Daniel Officer S-Sale D Common Stock 10,862 16.49 179.1K 534,351
2023-06-23 Harris Todd Director / Officer S-Sale D Common Stock 6,481 17.51 113.5K 1,601,276
2023-06-22 Harris Todd Director / Officer S-Sale D Common Stock 500 17.39 8.7K 1,621,988
2023-06-21 Harris Todd Director / Officer S-Sale D Common Stock 4,629 16.12 74.6K 1,640,593
2023-06-20 Harris Todd Director / Officer S-Sale D Common Stock 1,300 16.53 21.5K 1,645,222
2023-06-16 Harris Todd Director / Officer S-Sale D Common Stock 3,316 16.49 54.7K 1,697,960
2023-06-15 Harris Todd Director / Officer S-Sale D Common Stock 12,773 16.13 206.0K 1,701,276
2023-06-15 Bensen Daniel Officer M-Exempt A Common Stock 12,592 0.61 7.7K 540,573
2023-06-14 Bensen Daniel Officer M-Exempt D Stock Option (Right to Buy) 120 0.61 73.20 241,654
2023-06-13 Harris Todd Director / Officer M-Exempt D Stock Option (Right to Buy) 7,927 2.25 17.8K 389,610
2023-06-13 Bensen Daniel Officer M-Exempt D Stock Option (Right to Buy) 5,628 0.61 3.4K 241,774
2023-05-31 Verjee Rehan Director A-Award A Stock Option (Right to Buy) 14,500 14.47 209.8K 14,500
2023-05-31 Subramony Siddarth Director / 10% Owner A-Award A Stock Option (Right to Buy) 14,500 14.47 209.8K 14,500
2023-05-31 Simson Jake Director A-Award A Stock Option (Right to Buy) 14,500 14.47 209.8K 14,500
2023-05-31 RA CAPITAL MANAGEMENT, L.P. Director / 10% Owner A-Award A Stock Option (Right to Buy) 14,500 14.47 209.8K 14,500
2023-05-31 MORE ROBERT J Director A-Award A Stock Option (Right to Buy) 14,500 14.47 209.8K 14,500
2023-05-31 Kjellson Nina S Director A-Award A Stock Option (Right to Buy) 14,500 14.47 209.8K 14,500
2023-05-31 KAPLAN GILLA Director A-Award A Stock Option (Right to Buy) 14,500 14.47 209.8K 14,500
2023-05-31 CHEN ISAN Director A-Award A Stock Option (Right to Buy) 14,500 14.47 209.8K 14,500
2023-04-03 Harris Todd Director / Officer M-Exempt D Stock Option (Right to Buy) 2,000 2.25 4.5K 397,537
2023-04-03 Bensen Daniel Officer M-Exempt D Stock Option (Right to Buy) 2,000 0.61 1.2K 229,421
2023-03-31 Harris Todd Director / Officer M-Exempt D Stock Option (Right to Buy) 500 2.25 1.1K 399,537
2023-03-31 Bensen Daniel Officer M-Exempt A Common Stock 400 0.61 244.00 528,381
2023-03-30 Harris Todd Director / Officer M-Exempt A Common Stock 2,407 2.25 5.4K 1,703,683
2023-03-30 Bensen Daniel Officer S-Sale D Common Stock 2,000 16.01 32.0K 527,981
2023-03-29 Harris Todd Director / Officer M-Exempt A Common Stock 1,420 2.25 3.2K 1,702,696
2023-03-29 Bensen Daniel Officer M-Exempt D Stock Option (Right to Buy) 2,187 0.61 1.3K 233,821
2023-03-28 Harris Todd Director / Officer M-Exempt D Stock Option (Right to Buy) 2,779 2.25 6.3K 403,864
2023-03-28 Bensen Daniel Officer M-Exempt A Common Stock 3,346 0.61 2.0K 531,327
2023-03-27 Harris Todd Director / Officer M-Exempt D Stock Option (Right to Buy) 2,963 2.25 6.7K 406,643
2023-03-27 Bensen Daniel Officer M-Exempt A Common Stock 8,048 0.61 4.9K 536,029
2023-03-24 Harris Todd Director / Officer M-Exempt A Common Stock 170 2.25 382.50 1,701,446
2023-03-23 Harris Todd Director / Officer S-Sale D Common Stock 2,800 16.00 44.8K 1,701,276
2023-03-23 Bensen Daniel Officer M-Exempt D Stock Option (Right to Buy) 4,827 0.61 2.9K 247,402
2023-03-22 Harris Todd Director / Officer M-Exempt D Stock Option (Right to Buy) 4,043 2.25 9.1K 412,576
2023-03-22 Bensen Daniel Officer M-Exempt A Common Stock 3,800 0.61 2.3K 531,781
2023-03-21 Harris Todd Director / Officer M-Exempt D Stock Option (Right to Buy) 12,393 2.25 27.9K 416,619
2023-03-21 Bensen Daniel Officer M-Exempt A Common Stock 14,100 0.61 8.6K 542,081
2023-03-15 Tada Hiroomi Officer A-Award A Common Stock 1,893 6.58 12.5K 83,130
2023-03-15 Harris Todd Director / Officer A-Award A Common Stock 1,808 6.58 11.9K 1,701,276
2023-02-21 Patel Piyush R. Officer G-Gift D Common Stock 8,442 0.00 73,794
2023-02-10 MVA Investors, LLC 10% Owner S-Sale D Common Stock 65,568 13.40 878.6K 22,527
2023-02-09 MVA Investors, LLC 10% Owner S-Sale D Common Stock 200,000 13.10 2.62M 88,095
2023-01-01 Fuhrman Alan Officer A-Award A Stock Option (Right to Buy) 32,800 0.00 32,800
2022-10-12 Patel Piyush R. Officer G-Gift D Common Stock 56,276 0.00 82,236
2022-09-15 van den Boom Esther Officer A-Award A Common Stock 1,452 7.66 11.1K 121,897
2022-09-15 Tada Hiroomi Officer A-Award A Common Stock 612 7.66 4.7K 81,237
2022-09-15 Patel Piyush R. Officer A-Award A Common Stock 1,040 7.66 8.0K 138,512
2022-09-15 Hudkins Robert L. Officer A-Award A Common Stock 1,040 7.66 8.0K 273,576
2022-09-06 van den Boom Esther Officer A-Award A Stock Option (Right to Buy) 105,000 0.00 105,000
2022-09-06 Tada Hiroomi Officer A-Award A Common Stock 2,703 8.53 23.0K 80,625
2022-09-06 Swanson Ronald V. Officer A-Award A Common Stock 3,125 8.53 26.6K 273,254
2022-09-06 Patel Piyush R. Officer A-Award A Stock Option (Right to Buy) 30,924 0.00 30,924
2022-09-06 Hudkins Robert L. Officer A-Award A Common Stock 2,408 8.53 20.5K 272,536
2022-09-06 Harris Todd Officer A-Award A Common Stock 3,125 8.53 26.6K 1,699,468
2022-09-06 Bensen Daniel Officer A-Award A Stock Option (Right to Buy) 249,532 0.00 249,532
2022-06-13 Verjee Rehan Director A-Award A Stock Option (Right to Buy) 14,500 0.00 14,500
2022-06-13 Subramony Siddarth Director A-Award A Stock Option (Right to Buy) 14,500 0.00 14,500
2022-06-13 Simson Jake Director A-Award A Stock Option (Right to Buy) 14,500 0.00 14,500
2022-06-13 Shah Rajeev M. Director A-Award A Stock Option (Right to Buy) 14,500 0.00 14,500
2022-06-13 RA CAPITAL MANAGEMENT, L.P. Director / 10% Owner A-Award A Stock Option (Right to Buy) 14,500 5.38 78.0K 14,500
2022-06-13 MORE ROBERT J Director A-Award A Stock Option (Right to Buy) 14,500 0.00 14,500
2022-06-13 Kjellson Nina S Director A-Award A Stock Option (Right to Buy) 14,500 0.00 14,500
2022-06-13 KAPLAN GILLA Director A-Award A Stock Option (Right to Buy) 14,500 0.00 14,500
2022-06-13 CHEN ISAN Director A-Award A Stock Option (Right to Buy) 14,500 5.38 78.0K 14,500

Executive team

Top executives
Shares Outstanding
53.71M

Executive compensation

Executive compensation (annual)
# Year Executive Salary Bonus Stock award Option award Incentive Other Total % Stock-
based
Filing
1 2025 Todd Harris, Ph.D. Chief Executive Officer 658.0K 4.57M 325.7K 15.3K 5.57M 82.06%
2 2025 Bhavesh Ashar Chief Operating Officer 45.8K 4.64M 1.0K 4.69M 99.00%
3 2025 Douglas Warner, M.D. Chief Medical Officer 551.2K 1.61M 198.4K 15.1K 2.37M 67.77%
4 2024 Todd Harris, Ph.D. Chief Executive Officer 632.7K 6.50M 433.4K 950.00 7.57M 85.90%
5 2024 Douglas Warner, M.D. Chief Medical Officer 165.6K 4.47M 90.5K 313.00 4.73M 94.57%
6 2024 Daniel Bensen Chief Operating Officer 475.9K 1.92M 260.8K 950.00 2.66M 72.22%
7 2023 Todd Harris, Ph.D. Chief Executive Officer 608.4K 3.56M 456.3K 950.00 4.63M 76.96%
8 2023 Alan Fuhrman Chief Financial Officer 457.6K 2.77M 274.6K 30.9K 3.53M 78.39%
9 2023 Hiroomi Tada, M.D., Ph.D. Chief Medical Officer 509.6K 1.60M 305.8K 950.00 2.41M 66.16%
10 2023 Daniel Bensen Chief Operating Officer 457.6K 1.19M 274.6K 950.00 1.92M 61.82%
11 2022 Ali Fawaz General Counsel 275.0K 2.13M 193.6K 23.1K 2.62M 81.27%
12 2022 Daniel Bensen Chief Operating Officer 436.3K 1.80M 193.6K 950.00 2.43M 74.04%
13 2022 Todd Harris, Ph.D. Chief Executive Officer 580.6K 1.38M 321.8K 950.00 2.29M 60.51%
14 2022 Hiroomi Tada, M.D., Ph.D. Chief Medical Officer 486.3K 563.9K 215.6K 950.00 1.27M 44.52%
15 2021 Todd Harris, Ph.D. Chief Executive Officer 442.8K 5.76M 168.9K 986.00 6.38M 90.39%
16 2021 Ronald V. Swanson, Ph.D. Chief Scientific Officer 432.3K 1.99M 103.0K 921.00 2.53M 78.79%
17 2021 Hiroomi Tada, M.D., Ph.D. Chief Medical Officer 403.8K 1.99M 114.7K 1.1K 2.51M 79.31%
18 2021 Daniel Bensen Chief Operating Officer 355.1K 1.99M 103.0K 1.0K 2.45M 81.27%
19 2020 Todd Harris, Ph.D. Chief Executive Officer 350.2K 677.5K 210.1K 1.0K 1.24M 54.69%
20 2020 Ronald V. Swanson, Ph.D. Chief Scientific Officer 246.8K 128.3K 111.0K 900.00 487.0K 26.34%
CEO compensation breakdown

Proxy statements

Proxy statements (DEF 14A)
Filing date Form type Filing
2026-04-17 DEFA14A
2026-04-17 DEF 14A
2025-04-18 DEFA14A
2025-04-18 DEF 14A

Recent SEC filings

Recent SEC filings
Filing date Form type Filing
2026-05-13 8-K
2026-05-13 10-Q
2026-05-12 SC 13G/A
2026-05-07 4
2026-05-07 4
2026-05-07 4
2026-05-07 4
2026-05-07 4
2026-04-24 SC 13G/A
2026-04-20 4

Executive team

NameTitleCompensationGender
Todd Harris Co-Founder, CEO, President & Director 999.0K
Douglas Warner Chief Medical Officer 764.7K
Alan Fuhrman Chief Financial Officer 763.1K male
Daniel Bensen Co-Founder & Chief Discovery Officer 737.6K male
Ali D. Fawaz General Counsel & Secretary 629.2K male
Bhavesh Ashar Chief Operating Officer 551.0K male
Ronald V. Swanson Chief Scientific Officer 536.2K
Liz Pagano Chief Human Resources Officer
Ralph William Charlton Senior Vice President of Clinical Development
Erik Goluboff Senior Vice President of Clinical Development male
Sarah Honig Senior Vice President of Corporate Development & Strategy female
Robert L. Hudkins Chief Technology Officer
ESG Rating
B
BIOTECHNOLOGY
Rank: 393 out of 662
2026
E (Environmental)
59.7 / 56.3
Company / Sector avg.
S (Social)
74.9 / 62.4
Company / Sector avg.
G (Governance)
72.3 / 60.9
Company / Sector avg.
ESG Total
69.0 / 59.9
Company / Sector avg.
ESG Score History BIOTECHNOLOGY
Benchmark vs Sector
Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend history

Earnings history

Earnings reports

Stock splits