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ARS Pharmaceuticals, Inc. (SPRY)

USD7.22 -0.39 (-5.10%)
US NASDAQ Healthcare Biotechnology
Address 3525 Del Mar Heights Road 92130
San Diego, CA, US
CEO Richard E. Lowenthal
IPO 2020-12-04
CIK 1671858 ISIN US82835W1080

Explore sections of this company profile

Also trades on NASDAQ Global Market · SBTX (USD) NASDAQ Global Market · SPRY (USD)
Description

ARS Pharmaceuticals, Inc. specializes in creating ARS-1, an innovative intranasal epinephrine spray utilizing advanced absorption technology. This product serves as a crucial intervention for individuals and their households who are susceptible to life-threatening allergic reactions caused by food, pharmaceuticals, or insect stings. Among its offerings is Neffy, a low-dose version of its intranasal epinephrine nasal spray. Established in 2015, the firm operates out of San Diego, California.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
USD7.22 -0.39 (-5.10%)
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Volume Profile
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Liquidity & share structure
Average Volume
2M
Beta
0.83
Float Shares
62.62M
Free Float %
63.1%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
-6.49% -15.53% -9.23% -20.84% +1.43% -36.27% -47.93% -10.43% -73.94% -70.30% -70.30%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
vs.
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Analyst Consensus (10 ratings, all time) Hold
Price Targets & DCF
Current price
7.22
Low 25.00 +246.2%
Consensus 25.50 +253.1%
Median 25.50 +253.1%
High 26.00 +260.0%
Ratings Trend (MoM) 100% Bullish
Rating 2026-05 Change
Strong Buy 0 0
Buy 7 0
Hold 0 0
Sell 0 0
Strong Sell 0 0
Price Target Summary
Period # Analysts Avg Target
Last Month
Last Quarter 2
25.50
+253.1%
Last Year 4
28.25
+291.2%
All Time 9
23.89
+230.8%
Quality scores
Altman Z-Score
-0.89
Distress
Piotroski F-Score
3 / 9
Average
MOAT Score
0 / 10
No MOAT
Composite Rating
D+
Overall Score
1 / 5
Low
DCF Score
1 / 5
Low
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
1 / 5
Low
P/E Score
1 / 5
Low
P/Book Score
1 / 5
Low
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
    -5.5% Q1'26: +184.5% (vs Q1'25)
  • EPS growth Biotechnology: +29.7%
    -2,327.9% Q1'26: -74.3% (vs Q1'25)
  • FCF margin FCF growth · Biotechnology: +16.2%
    -238.4% Q1'26: -198.2% (vs Q1'25)
  • EBIT margin Biotechnology: +0.0%
    -212.9% Q1'26: -265.2% (vs Q1'25)
  • ROIC Biotechnology: -16.1%
    Q1'26: +565.4% (vs Q1'25)
  • Share dilution Biotechnology: -3.4%
    -3.7% Q1'26: +1.3% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    -0.54× Q1'26: -0.40× (vs Q1'25)
Valuation Multiples From To
Price Forecast (3Y) From To
Model
Adjust
P/E
Theoretical Return — If Invested Today

* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.

DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (0.80) × ERP
WACC = 88% × Ke + 12% × Kd (4.3%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Current price: 7.22
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2022
actual
Dec 2023
actual
Dec 2024
actual
Dec 2025
actual
Dec 2026
4 Rev. Ana.
4 EPS Ana.
Dec 2027
4 Rev. Ana.
4 EPS Ana.
Dec 2028
4 Rev. Ana.
4 EPS Ana.
Dec 2029
3 Rev. Ana.
2 EPS Ana.
Dec 2030
3 Rev. Ana.
2 EPS Ana.
Revenue
1.32M
est: 1.27M (+3.8%)
30.0K
est: 500.0K (-94.0%)
89.15M
est: 8.48M (+951.3%)
84.28M
est: 81.73M (+3.1%)
149.16M
136.94M – 162.56M
+82.5% YoY
274.26M
245.58M – 292.47M
+83.9% YoY
452.99M
447.82M – 458.16M
+65.2% YoY
610.57M
536.11M – 668.56M
+34.8% YoY
677.00M
594.44M – 741.31M
+10.9% YoY
EBITDA
-35.20M
est: -776.1K (-4,434.9%)
-67.45M
est: -403.4K (-16,620.9%)
-3.00M
est: -6.84M (+56.1%)
-178.08M
est: -65.94M (-170.1%)
-120.33M
-131.14M – -110.48M
-82.5% YoY
-221.26M
-235.95M – -198.12M
-83.9% YoY
-365.44M
-369.62M – -361.27M
-65.2% YoY
-492.57M
-539.36M – -432.50M
-34.8% YoY
-546.16M
-598.04M – -479.56M
-10.9% YoY
EBIT
-35.52M
est: -776.4K (-4,474.2%)
-67.52M
est: -403.5K (-16,635.3%)
-3.08M
est: -6.84M (+54.9%)
-179.45M
est: -65.95M (-172.1%)
-120.36M
-131.17M – -110.50M
-82.5% YoY
-221.30M
-236.00M – -198.17M
-83.9% YoY
-365.52M
-369.70M – -361.35M
-65.2% YoY
-492.68M
-539.47M – -432.59M
-34.8% YoY
-546.28M
-598.17M – -479.66M
-10.9% YoY
Net Income
-34.68M
est: -102.18M (+66.1%)
-54.37M
est: -44.84M (-21.2%)
8.00M
est: -48.02M (+116.7%)
-171.30M
est: -166.46M (-2.9%)
-176.22M
-202.99M – -124.11M
-5.9% YoY
-93.63M
-111.87M – -39.16M
+46.9% YoY
16.28M
-84.31M – 84.31M
+117.4% YoY
97.58M
82.11M – 109.63M
+499.5% YoY
122.22M
102.85M – 137.31M
+25.3% YoY
SGA
18.66M
est: 403.65M (-95.4%)
47.28M
est: 159.39M (-70.3%)
est: 2.70B (-100.0%)
230.12M
est: 26.05B (-99.1%)
47.55B
43.65B – 51.82B
+82.5% YoY
87.43B
78.29B – 93.23B
+83.9% YoY
144.40B
142.75B – 146.05B
+65.2% YoY
194.64B
170.90B – 213.12B
+34.8% YoY
215.81B
189.49B – 236.31B
+10.9% YoY
EPS
-0.87
est: -0.94 (+7.5%)
-0.57
est: -0.47 (-22.4%)
0.08
est: -0.66 (+112.5%)
-1.74
est: -1.72 (-1.3%)
-1.72
-2.06 – -1.26
+0.0% YoY
-0.91
-1.14 – -0.40
+47.1% YoY
0.14
-0.86 – 0.86
+115.4% YoY
0.99
0.83 – 1.11
+609.9% YoY
1.24
1.04 – 1.39
+25.3% YoY
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-15 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-14 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-13 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-12 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-11 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-08 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-07 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-06 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-05 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-04 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-01 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-30 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-29 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-28 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-27 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-24 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-23 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-22 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-21 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-20 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-17 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-16 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
-175.22M
OE per share TTM
-1.77
Owner's Yield
-23.75%
Maintenance CapEx ratio
Maint CapEx / Avg PPE
5.3%

Ownership Overview

Ownership breakdown
At a glance
Institutional holders
128
Total invested
289.19M
Insider transactions (90d)
0
Beneficial owners (>5%)
4
Beneficial owners (>5%)
# Reporting person Amount owned % of class Sole voting Shared voting Sole dispositive Shared dispositive Type Citizenship Filing date SEC filing
1 Peter Kolchinsky 6.76M 7.07% 6.76M 10.00 HC, IN or Place of Organization.        United States 2023-08-31
2 RA Capital Management, L.P. 6.76M 7.07% 6.76M 10.00 IA, PN Delaware 2023-08-31
3 Rajeev Shah 6.76M 7.07% 6.76M 10.00 HC, IN States 2023-08-31
4 RA Capital Healthcare Fund, L.P. 5.86M 6.13% 5.86M 10.00 HC, IN States 2023-08-31

Institutional Activity (13F)

Institutional ownership trend From To
13F snapshot — 2026 Q1
Investors holding
128
-67 vs prev Q
New positions
24
Closed positions
88
Increased
62
Reduced
35
Put/Call ratio
0.00
Calls held
29.7K
Puts held
Top institutional holders
# Investor Shares / Δ Mkt value / Δ Own% / Δ Weight% / Δ Avg px / Perf. Hold / Status
1 RA CAPITAL MANAGEMENT, L.P. 10.86M +— (+0.0%) 126.53M +17.4M (+15.9%) 10.99% -0.050 pp 1.30% -0.049 pp USD5.83 +99.8% 13 qtrs
2 ORBIMED ADVISORS LLC 8.29M +— (+0.0%) 96.56M +13.3M (+15.9%) 8.39% -0.038 pp 1.98% +0.016 pp USD44.04 -73.5% 21 qtrs
3 DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C) 7.50M +— (+0.0%) 87.42M +12.0M (+15.9%) 7.59% -0.034 pp 1.12% -0.035 pp USD8.53 +36.6% 13 qtrs
4 RUBRIC CAPITAL MANAGEMENT LP 6.20M +1.7M (+37.8%) 72.23M +27.0M (+59.7%) 6.27% +1.700 pp 0.86% +0.354 pp USD11.23 +3.7% 4 qtrs
5 BLACKROCK, INC. 5.09M +254.0K (+5.3%) 59.24M +10.7M (+22.0%) 5.15% +0.235 pp 0.00% +0.000 pp USD13.83 -15.8% 6 qtrs
6 SR ONE CAPITAL MANAGEMENT, LP 4.01M +— (+0.0%) 46.75M +6.4M (+15.9%) 4.06% -0.018 pp 6.62% +0.785 pp USD8.02 +45.3% 13 qtrs
7 ABRDN PLC 3.56M +459.0K (+14.8%) 41.43M +10.3M (+33.1%) 3.60% +0.450 pp 0.06% +0.015 pp USD12.01 -3.0% 4 qtrs
8 VANGUARD GROUP INC 3.51M +8.9K (+0.3%) 40.88M +5.7M (+16.2%) 3.55% -0.007 pp 0.00% +0.000 pp USD13.09 -11.0% 21 qtrs
9 STATE STREET CORP 3.22M +328.3K (+11.3%) 37.55M +8.5M (+29.1%) 3.26% +0.319 pp 0.00% +0.000 pp USD10.50 +11.0% 20 qtrs
10 MILLENNIUM MANAGEMENT LLC 3.17M +3.2M (+100.0%) 36.91M +36.9M (+100.0%) 3.21% +3.207 pp 0.02% +0.016 pp USD11.65 +0.0% 6 qtrs
11 FRANKLIN RESOURCES INC 2.54M +145.1K (+6.1%) 29.63M +5.5M (+22.9%) 2.57% +0.136 pp 0.01% +0.001 pp USD5.70 +104.4% 10 qtrs
12 UBS GROUP AG 2.21M +1.6M (+235.0%) 25.76M +19.1M (+288.4%) 2.24% +1.567 pp 0.00% +0.003 pp USD12.00 -2.9% 9 qtrs
13 TYRO CAPITAL MANAGEMENT LLC 1.99M +2.0M (+100.0%) 23.24M +23.2M (+100.0%) 2.02% +2.019 pp 4.16% +4.159 pp USD11.65 +0.0% 1 qtrs NEW
14 CITADEL ADVISORS LLC 1.95M +368.4K (+23.2%) 22.77M +6.8M (+42.8%) 1.98% +0.366 pp 0.00% +0.001 pp USD14.52 -19.8% 21 qtrs
15 CASDIN CAPITAL, LLC 1.60M +— (+0.0%) 18.64M +2.6M (+15.9%) 1.62% -0.007 pp 1.16% -0.183 pp USD10.05 +15.9% 2 qtrs
16 GEODE CAPITAL MANAGEMENT, LLC 1.55M +47.3K (+3.1%) 18.09M +3.0M (+19.6%) 1.57% +0.041 pp 0.00% +0.000 pp USD10.80 +7.9% 21 qtrs
17 SOUTHPOINT CAPITAL ADVISORS LP 1.50M +— (+0.0%) 17.48M +2.4M (+15.9%) 1.52% -0.007 pp 0.41% +0.011 pp USD17.45 -33.2% 3 qtrs
18 JANNEY MONTGOMERY SCOTT LLC 1.29M +74.8K (+6.2%) 15.00M +2.8M (+23.1%) 1.30% +0.070 pp 0.03% +0.006 pp USD11.86 -1.8% 21 qtrs
19 BAMCO INC /NY/ 1.27M +— (+0.0%) 14.78M +2.0M (+15.9%) 1.28% -0.006 pp 0.04% +0.006 pp USD10.28 +13.3% 3 qtrs
20 GOLDMAN SACHS GROUP INC 812.0K -513.7K (-38.7%) 9.46M -3.9M (-29.0%) 0.82% -0.526 pp 0.00% -0.001 pp USD13.71 -15.0% 18 qtrs
21 FIL LTD 810.1K +810.1K (+100.0%) 9.44M +9.4M (+100.0%) 0.82% +0.820 pp 0.01% +0.007 pp USD11.65 +0.0% 1 qtrs NEW
22 LEVIN CAPITAL STRATEGIES, L.P. 747.5K -16.8K (-2.2%) 8.71M +1.0M (+13.4%) 0.76% -0.021 pp 0.75% +0.057 pp USD10.86 +7.3% 13 qtrs
23 NEXTECH INVEST, LTD. 660.7K +— (+0.0%) 7.70M +1.1M (+15.9%) 0.67% -0.003 pp 0.74% -0.267 pp USD12.58 -7.4% 4 qtrs
24 BANK OF MONTREAL /CAN/ 643.4K +643.4K (+100.0%) 7.50M +7.5M (+100.0%) 0.65% +0.651 pp 0.00% +0.003 pp USD11.65 +0.0% 1 qtrs NEW
25 CENTERBOOK PARTNERS LP 568.4K +56.0K (+10.9%) 6.62M +1.5M (+28.6%) 0.58% +0.054 pp 0.32% +0.069 pp USD10.21 +14.1% 2 qtrs
26 RAYMOND JAMES FINANCIAL INC 566.1K -190.3K (-25.2%) 6.59M -1.0M (-13.2%) 0.57% -0.196 pp 0.00% 0.000 pp USD10.71 +8.8% 5 qtrs
27 GENERAL AMERICAN INVESTORS CO INC 560.0K +560.0K (+100.0%) 6.52M +6.5M (+100.0%) 0.57% +0.567 pp 0.37% +0.368 pp USD11.65 +0.0% 1 qtrs NEW
28 THIRD POINT LLC 556.2K +556.2K (+100.0%) 6.48M +6.5M (+100.0%) 0.56% +0.563 pp 0.09% +0.089 pp USD11.65 +0.0% 1 qtrs NEW
29 MORGAN STANLEY 552.4K -148.1K (-21.1%) 6.44M -604.1K (-8.6%) 0.56% -0.153 pp 0.00% +0.000 pp USD11.65 +0.0% 21 qtrs
30 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 550.9K +30.2K (+5.8%) 6.42M +1.2M (+22.6%) 0.56% +0.028 pp 0.00% +0.000 pp USD7.15 +62.9% 20 qtrs
31 NORTHERN TRUST CORP 521.0K -10.5K (-2.0%) 6.07M +728.2K (+13.6%) 0.53% -0.013 pp 0.00% +0.000 pp USD11.74 -0.8% 20 qtrs
32 BANK OF AMERICA CORP /DE/ 482.1K +210.1K (+77.2%) 5.62M +2.9M (+105.4%) 0.49% +0.211 pp 0.00% +0.000 pp USD11.15 +4.5% 20 qtrs
33 AMERICAN CENTURY COMPANIES INC 455.8K +455.8K (+100.0%) 5.31M +5.3M (+100.0%) 0.46% +0.461 pp 0.00% +0.003 pp USD11.65 +0.0% 12 qtrs
34 ALYESKA INVESTMENT GROUP, L.P. 418.9K +28.8K (+7.4%) 4.88M +959.6K (+24.5%) 0.42% +0.027 pp 0.01% +0.002 pp USD10.78 +8.1% 6 qtrs
35 JPMORGAN CHASE & CO 417.1K +382.0K (+1,089.7%) 4.86M +4.5M (+1,279.1%) 0.42% +0.387 pp 0.00% +0.000 pp USD11.33 +2.8% 20 qtrs
36 FMR LLC 399.0K -343.5K (-46.3%) 4.65M -2.8M (-37.7%) 0.40% -0.351 pp 0.00% 0.000 pp USD27.21 -57.2% 21 qtrs
37 LISANTI CAPITAL GROWTH, LLC 396.5K +185.3K (+87.8%) 4.62M +2.5M (+117.6%) 0.40% +0.187 pp 1.09% +0.575 pp USD13.54 -14.0% 4 qtrs
38 ADAR1 CAPITAL MANAGEMENT, LLC 369.6K +310.3K (+524.0%) 4.31M +3.7M (+623.3%) 0.37% +0.314 pp 0.32% +0.260 pp USD11.39 +2.3% 2 qtrs
39 EMPIRE LIFE INVESTMENTS INC. 352.6K -3.1K (-0.9%) 4.11M +533.2K (+14.9%) 0.36% -0.005 pp 0.23% +0.022 pp USD10.05 +15.9% 2 qtrs
40 INVESTMENT MANAGEMENT ASSOCIATES INC /ADV 311.5K +311.5K (+100.0%) 3.63M +3.6M (+100.0%) 0.32% +0.315 pp 1.00% +1.001 pp USD11.65 +0.0% 1 qtrs NEW
41 UBS ASSET MANAGEMENT AMERICAS INC 304.4K -30.7K (-9.2%) 3.55M +178.5K (+5.3%) 0.31% -0.033 pp 0.00% +0.000 pp USD13.78 -15.5% 10 qtrs
42 295.9K +295.9K (+100.0%) 3.45M +3.4M (+100.0%) 0.30% +0.299 pp 2.40% +2.405 pp USD11.65 +0.0% 1 qtrs NEW
43 EVERSEPT PARTNERS, LP 251.6K -724.9K (-74.2%) 2.93M -6.9M (-70.1%) 0.25% -0.738 pp 0.15% -0.529 pp USD10.05 +15.9% 2 qtrs
44 SUSQUEHANNA INTERNATIONAL GROUP, LLP 226.8K -33.5K (-12.9%) 2.64M +26.2K (+1.0%) 0.23% -0.035 pp 0.00% +0.000 pp USD10.90 +6.9% 15 qtrs
45 STEWARD PARTNERS INVESTMENT ADVISORY, LLC 216.3K +69.6K (+47.4%) 2.52M +1.0M (+70.9%) 0.22% +0.070 pp 0.01% +0.005 pp USD13.93 -16.4% 12 qtrs
46 ROYCE & ASSOCIATES LP 207.1K +207.1K (+100.0%) 2.41M +2.4M (+100.0%) 0.21% +0.210 pp 0.02% +0.025 pp USD11.65 +0.0% 12 qtrs
47 FAS WEALTH PARTNERS, INC. 202.4K +1.8K (+0.9%) 2.36M +341.8K (+17.0%) 0.20% +0.001 pp 0.15% +0.016 pp USD10.36 +12.5% 11 qtrs
48 BOOTHBAY FUND MANAGEMENT, LLC 201.5K +201.5K (+100.0%) 2.35M +2.3M (+100.0%) 0.20% +0.204 pp 0.04% +0.035 pp USD11.65 +0.0% 3 qtrs
49 BARCLAYS PLC 196.4K +84.7K (+75.9%) 2.29M +668.8K (+41.3%) 0.20% +0.085 pp 0.00% +0.000 pp USD14.20 -18.0% 16 qtrs
50 DAFNA CAPITAL MANAGEMENT LLC 190.1K +49.6K (+35.3%) 2.21M +802.2K (+56.8%) 0.19% +0.050 pp 0.51% +0.166 pp USD10.47 +11.3% 9 qtrs
51 K2 PRINCIPAL FUND, L.P. 181.1K +117.9K (+186.6%) 2.11M +1.5M (+232.2%) 0.18% +0.119 pp 0.17% +0.118 pp USD11.09 +5.0% 12 qtrs
52 DIMENSIONAL FUND ADVISORS LP 176.1K -2.0K (-1.1%) 2.05M +261.4K (+14.6%) 0.18% -0.003 pp 0.00% +0.000 pp USD5.46 +113.4% 15 qtrs
53 WEXFORD CAPITAL LP 165.3K -2.9K (-1.7%) 1.93M +235.1K (+13.9%) 0.17% -0.004 pp 0.37% +0.129 pp USD13.15 -11.4% 6 qtrs
54 BANK OF NEW YORK MELLON CORP 163.0K +8.4K (+5.4%) 1.90M +345.2K (+22.2%) 0.17% +0.008 pp 0.00% +0.000 pp USD8.91 +30.8% 13 qtrs
55 QUINN OPPORTUNITY PARTNERS LLC 155.0K +30.0K (+24.0%) 1.81M +549.5K (+43.7%) 0.16% +0.030 pp 0.08% -0.013 pp USD11.09 +5.0% 4 qtrs
56 WOODLINE PARTNERS LP 150.9K +— (+0.0%) 1.76M +241.5K (+15.9%) 0.15% -0.001 pp 0.01% 0.000 pp USD11.87 -1.9% 21 qtrs
57 TREXQUANT INVESTMENT LP 150.1K -481.6K (-76.2%) 1.75M -4.6M (-72.5%) 0.15% -0.490 pp 0.02% -0.050 pp USD10.05 +15.9% 8 qtrs
58 NUVEEN, LLC 149.6K +— (+0.0%) 1.74M +239.4K (+15.9%) 0.15% -0.001 pp 0.00% +0.000 pp USD12.40 -6.0% 4 qtrs
59 KNIGHTS OF COLUMBUS ASSET ADVISORS LLC 130.7K -3.7K (-2.8%) 1.52M +171.5K (+12.7%) 0.13% -0.004 pp 0.09% +0.009 pp USD12.23 -4.7% 4 qtrs
60 RAFFERTY ASSET MANAGEMENT, LLC 115.6K -6.8K (-5.6%) 1.35M +116.1K (+9.4%) 0.12% -0.008 pp 0.00% +0.001 pp USD10.31 +13.0% 8 qtrs
61 PRINCIPAL FINANCIAL GROUP INC 112.8K +35.9K (+46.7%) 1.31M +541.0K (+70.0%) 0.11% +0.036 pp 0.00% +0.000 pp USD14.20 -18.0% 3 qtrs
62 LEGATO CAPITAL MANAGEMENT LLC 109.1K +69.7K (+176.8%) 1.27M +874.9K (+220.9%) 0.11% +0.070 pp 0.11% +0.066 pp USD12.26 -5.0% 6 qtrs
63 SWISS NATIONAL BANK 107.2K +22.9K (+27.2%) 1.25M +401.7K (+47.4%) 0.11% +0.023 pp 0.00% +0.000 pp USD9.33 +24.9% 11 qtrs
64 SIT INVESTMENT ASSOCIATES INC 92.9K +18.4K (+24.6%) 1.08M +333.0K (+44.5%) 0.09% +0.018 pp 0.02% +0.006 pp USD13.58 -14.2% 3 qtrs
65 CAMBRIDGE INVESTMENT RESEARCH ADVISORS, INC. 87.2K +— (+0.0%) 1.02M +139.0K (+15.9%) 0.09% 0.000 pp 0.00% +0.000 pp USD14.50 -19.7% 6 qtrs
66 VALLEY FORGE INVESTMENT CONSULTANTS INC ADV 83.2K +— (+0.0%) 969.6K +133.2K (+15.9%) 0.08% 0.000 pp 0.28% +0.037 pp USD14.50 -19.7% 6 qtrs
67 ALPS ADVISORS INC 81.2K +31.6K (+63.6%) 945.6K +447.1K (+89.7%) 0.08% +0.032 pp 0.01% +0.003 pp USD15.19 -23.3% 3 qtrs
68 MARSHALL WACE, LLP 79.2K -118.1K (-59.9%) 922.8K -1.1M (-53.5%) 0.08% -0.120 pp 0.00% -0.001 pp USD10.69 +9.0% 6 qtrs
69 SG AMERICAS SECURITIES, LLC 76.2K +66.1K (+654.1%) 888.0K +786.0K (+770.6%) 0.08% +0.067 pp 0.00% +0.001 pp USD11.27 +3.4% 8 qtrs
70 ASSUREDPARTNERS INVESTMENT ADVISORS, LLC 75.8K +18.0K (+31.1%) 882.8K +302.1K (+52.0%) 0.08% +0.018 pp 0.13% +0.002 pp USD11.68 -0.3% 5 qtrs
71 SEI INVESTMENTS CO 74.8K +26.7K (+55.5%) 871.5K +388.0K (+80.2%) 0.08% +0.027 pp 0.00% +0.000 pp USD10.94 +6.5% 5 qtrs
72 WELLS FARGO & COMPANY/MN 74.3K +414.0 (+0.6%) 865.1K +123.0K (+16.6%) 0.08% +0.000 pp 0.00% +0.000 pp USD11.17 +4.3% 20 qtrs
73 RHUMBLINE ADVISERS 73.3K -7.9K (-9.7%) 853.9K +37.8K (+4.6%) 0.07% -0.008 pp 0.00% +0.000 pp USD9.29 +25.4% 11 qtrs
74 HRT FINANCIAL LP 68.6K +68.6K (+100.0%) 799.0K +799.0K (+100.0%) 0.07% +0.070 pp 0.00% +0.003 pp USD11.65 +0.0% 1 qtrs NEW
75 ALLIANCEBERNSTEIN L.P. 60.1K -2.6M (-97.7%) 700.4K -25.9M (-97.4%) 0.06% -2.625 pp 0.00% -0.008 pp USD10.48 +11.2% 11 qtrs
76 LEGAL & GENERAL GROUP PLC 58.4K +3.1K (+5.7%) 680.0K +124.8K (+22.5%) 0.06% +0.003 pp 0.00% +0.000 pp USD10.93 +6.6% 12 qtrs
77 MATISSE CAPITAL 55.6K -2.2K (-3.9%) 647.3K +66.5K (+11.4%) 0.06% -0.003 pp 0.29% +0.027 pp USD12.62 -7.7% 4 qtrs
78 AMERICAN ASSETS INC 55.0K +— (+0.0%) 640.8K +88.0K (+15.9%) 0.06% 0.000 pp 0.20% +0.026 pp USD10.05 +15.9% 2 qtrs
79 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 54.1K +9.7K (+21.9%) 630.2K +184.1K (+41.3%) 0.05% +0.010 pp 0.00% +0.000 pp USD8.55 +36.3% 11 qtrs
80 COASTAL BRIDGE ADVISORS, LLC 53.8K -37.8K (-41.3%) 627.1K -294.2K (-31.9%) 0.05% -0.039 pp 0.05% -0.023 pp USD14.59 -20.2% 4 qtrs
81 QUANTINNO CAPITAL MANAGEMENT LP 53.1K +12.6K (+31.2%) 618.8K +212.0K (+52.1%) 0.05% +0.013 pp 0.00% +0.000 pp USD10.43 +11.7% 2 qtrs
82 PERMANENT CAPITAL MANAGEMENT, LP 52.3K -1.0K (-1.9%) 609.4K +73.3K (+13.7%) 0.05% -0.001 pp 0.12% +0.019 pp USD10.05 +15.9% 2 qtrs
83 SCHULHOFF & CO INC 51.2K +7.7K (+17.6%) 595.9K +158.7K (+36.3%) 0.05% +0.008 pp 0.25% +0.064 pp USD12.73 -8.5% 4 qtrs
84 DEUTSCHE BANK AG\ 48.7K +6.8K (+16.2%) 567.7K +146.1K (+34.6%) 0.05% +0.007 pp 0.00% +0.000 pp USD9.70 +20.1% 9 qtrs
85 LOS ANGELES CAPITAL MANAGEMENT LLC 65.7K +65.7K (+100.0%) 566.7K +566.7K (+100.0%) 0.07% +0.067 pp 0.00% +0.002 pp USD11.65 +0.0% 1 qtrs NEW
86 PROFUND ADVISORS LLC 42.8K +16.5K (+62.6%) 498.7K +234.1K (+88.5%) 0.04% +0.017 pp 0.02% +0.007 pp USD10.84 +7.5% 8 qtrs
87 FOX RUN MANAGEMENT, L.L.C. 38.6K +38.6K (+100.0%) 449.5K +449.5K (+100.0%) 0.04% +0.039 pp 0.07% +0.069 pp USD11.65 +0.0% 1 qtrs NEW
88 INVESCO LTD. 37.2K -2.9K (-7.2%) 433.7K +30.6K (+7.6%) 0.04% -0.003 pp 0.00% +0.000 pp USD15.67 -25.7% 13 qtrs
89 XTX TOPCO LTD 37.2K -106.4K (-74.1%) 433.4K -1.0M (-70.0%) 0.04% -0.108 pp 0.01% -0.064 pp USD10.36 +12.5% 6 qtrs
90 AQUATIC CAPITAL MANAGEMENT LLC 36.0K -69.7K (-65.9%) 419.8K -643.0K (-60.5%) 0.04% -0.071 pp 0.01% -0.008 pp USD13.46 -13.4% 3 qtrs
91 METLIFE INVESTMENT MANAGEMENT, LLC 34.3K +— (+0.0%) 400.0K +54.9K (+15.9%) 0.03% 0.000 pp 0.00% +0.000 pp USD8.27 +40.9% 11 qtrs
92 VOYA INVESTMENT MANAGEMENT LLC 34.1K -80.7K (-70.3%) 397.6K -756.7K (-65.6%) 0.03% -0.082 pp 0.00% -0.001 pp USD15.25 -23.6% 7 qtrs
93 MIRAE ASSET GLOBAL ETFS HOLDINGS LTD. 34.1K +438.0 (+1.3%) 397.2K +61.0K (+18.1%) 0.03% +0.000 pp 0.00% +0.000 pp USD11.54 +1.0% 7 qtrs
94 PRICE T ROWE ASSOCIATES INC /MD/ 33.8K +— (+0.0%) 394.0K +54.0K (+15.9%) 0.03% 0.000 pp 0.00% +0.000 pp USD13.93 -16.4% 7 qtrs
95 DIKER MANAGEMENT LLC 33.5K -10.0K (-23.0%) 390.4K -46.9K (-10.7%) 0.03% -0.010 pp 0.30% -0.051 pp USD14.67 -20.6% 4 qtrs
96 QUEST PARTNERS LLC 33.0K -12.8K (-28.0%) 384.1K -76.4K (-16.6%) 0.03% -0.013 pp 0.02% -0.009 pp USD11.84 -1.6% 5 qtrs
97 MANUFACTURERS LIFE INSURANCE COMPANY, THE 32.1K -415.0 (-1.3%) 373.5K +47.1K (+14.4%) 0.03% -0.001 pp 0.00% +0.000 pp USD12.54 -7.1% 7 qtrs
98 PRIVATE ADVISOR GROUP, LLC 31.5K +10.9K (+52.9%) 366.5K +159.7K (+77.2%) 0.03% +0.011 pp 0.00% +0.001 pp USD10.60 +9.9% 2 qtrs
Ownership breakdown by holder

ETF Ownership

Top ETFs holding this stock Held by 79 ETFs in our universe
# ETF Weight Est. AUM exposure TER
1 Global X - S&P Biotech ETF CURE.AX 0.17% 60.6K 0.45%
2 State Street SPDR S&P Biotech ETF XBI 0.17% 18.21M 0.35%
3 Invesco NASDAQ Biotech UCITS ETF SBIO.L 0.05% 251.1K 0.40%
4 Invesco Nasdaq Biotechnology ETF IBBQ 0.05% 40.5K 0.19%
5 iShares Nasdaq US Biotechnology UCITS ETF BTEC.L 0.05% 584.6K 0.35%
6 iShares Nasdaq US Biotechnology UCITS ETF BTEE.L 0.05% 39.1K 0.35%
7 iShares U.S. Small-Cap Equity Factor ETF SMLF 0.04% 1.63M 0.15%
8 iShares Biotechnology ETF IBB 0.04% 3.58M 0.44%
9 Pacer WealthShield ETF PWS 0.03% 8.4K 0.60%
10 ProShares Ultra Nasdaq Biotechnology BIB 0.03% 26.4K 1.19%

Insider Activity

Insider Activity — Latest Quarter
Ratio by transactions
0.29
Bearish
Ratio by volume
0.09
Bearish
Buys
2
Sells
7
Shares acquired
51.8K
Shares disposed
590.0K
Cash buys
Cash sales
3.00
Net activity
-538,208
Insider buys vs sells (history) From To
Recent insider transactions From To
Date Person Role Transaction A/D Security Shares Price Value Owned after D/I Filing
2026-01-02 Tanimoto Sarina Officer / 10% Owner A-Award A Stock Option (right to buy) 875,000 11.49 10.05M 875,000 I
2026-01-02 Scott Kathleen D. Officer A-Award A Stock option (right to buy) 240,000 11.49 2.76M 240,000 D
2026-01-02 Lowenthal Richard E Director / Officer / 10% Owner A-Award A Stock option (right to buy) 875,000 11.49 10.05M 875,000 D
2026-01-02 Karas Eric Officer A-Award A Stock option (right to buy) 240,000 11.49 2.76M 240,000 D
2026-01-02 Fitzpatrick Alexander A Officer A-Award A Stock option (right to buy) 240,000 11.49 2.76M 240,000 D
2026-01-02 Dorsey Brian Officer A-Award A Stock option (right to buy) 240,000 11.49 2.76M 240,000 D
2026-01-02 Chakma Justin Officer A-Award A Stock option (right to buy) 240,000 11.49 2.76M 240,000 D
2025-11-13 Dorsey Brian Officer M-Exempt A Common Stock 21,828 0.64 14.0K 32,617 D
2025-11-12 Shah Pratik Director G-Gift D Common Stock 100,000 0.00 4,474,554 I
2025-11-12 Chakma Justin Officer S-Sale D Common Stock 136,380 8.86 1.21M 0 D
2025-08-21 Scott Kathleen D. Officer M-Exempt D Stock Option (Right to Buy) 12,500 1.50 18.8K 739,830 D
2025-08-21 Lowenthal Richard E Director / Officer / 10% Owner S-Sale D Common Stock 50,000 14.49 724.3K 1,196,494 I
2025-08-20 Tanimoto Sarina Officer / 10% Owner S-Sale D Common Stock 37,656 14.09 530.6K 1,247,447 I
2025-08-19 Tanimoto Sarina Officer / 10% Owner S-Sale D Common Stock 12,344 14.03 173.1K 1,285,103 I
2025-07-01 Karas Eric Officer S-Sale D Common Stock 15,000 16.99 254.9K 10,315 D
2025-06-27 Flynn James E 10% Owner S-Sale D Class A Common Stock 370,074 18.46 6.83M 4,887,254 I
2025-06-25 Thompson Peter A. Director A-Award A Stock Option (right to buy) 30,000 17.26 517.8K 30,000 D
2025-06-25 Shawver Laura Director A-Award A Stock Option (right to buy) 30,000 17.26 517.8K 30,000 D
2025-06-25 Shah Pratik Director A-Award A Stock Option (right to buy) 30,000 17.26 517.8K 30,000 D
2025-06-25 SCHNEIDER PHILLIP M Director A-Award A Stock Option (right to buy) 30,000 17.26 517.8K 30,000 D
2025-06-25 SAUNDERS BRENT L Director A-Award A Stock Option (right to buy) 30,000 17.26 517.8K 30,000 D
2025-06-25 RA CAPITAL MANAGEMENT, L.P. Director / 10% Owner A-Award A Stock Option (Right to Buy) 30,000 17.26 517.8K 30,000 I
2025-06-25 Kelly Michael Director A-Award A Stock Option (right to buy) 30,000 17.26 517.8K 30,000 D
2025-06-25 Islam Saqib Director A-Award A Stock Option (right to buy) 30,000 17.26 517.8K 30,000 D
2025-06-25 Dadoo Rajeev Director A-Award A Stock Option (right to buy) 30,000 17.26 517.8K 30,000 D
2025-06-18 Karas Eric Officer M-Exempt D Stock Option (Right to Buy) 15,000 1.50 22.5K 559,588 D
2025-05-20 Scott Kathleen D. Officer M-Exempt A Common Stock 50,000 1.50 75.0K 57,424 D
2025-05-20 SAUNDERS BRENT L Director S-Sale D Common Stock 120,000 14.25 1.71M 0 D
2025-05-20 Fitzpatrick Alexander A Officer M-Exempt A Common Stock 100,000 5.58 558.0K 192,582 D
2025-04-07 Shawver Laura Director M-Exempt D Stock Option (Right to Buy) 27,493 4.85 133.3K 24,062 D
2025-03-20 Karas Eric Officer M-Exempt A Common Stock 10,000 1.50 15.0K 17,696 D
2025-03-06 Shawver Laura Director M-Exempt A Common Stock 49,600 4.85 240.6K 259,946 D
2025-03-05 Shawver Laura Director M-Exempt A Common Stock 400 4.85 1.9K 210,746 D
2025-02-03 Shawver Laura Director M-Exempt A Common Stock 40,936 4.85 198.5K 260,346 D
2025-01-06 Shawver Laura Director S-Sale D Common Stock 50,000 11.10 555.1K 210,346 D
2025-01-02 Tanimoto Sarina Officer / 10% Owner A-Award A Stock Option (right to buy) 767,600 10.71 8.22M 767,600 I
2025-01-02 Scott Kathleen D. Officer A-Award A Stock option (right to buy) 176,700 10.71 1.89M 176,700 D
2025-01-02 Lowenthal Richard E Director / Officer / 10% Owner A-Award A Stock option (right to buy) 767,600 10.71 8.22M 767,600 D
2025-01-02 Karas Eric Officer A-Award A Stock option (right to buy) 152,300 10.71 1.63M 152,300 D
2025-01-02 Fitzpatrick Alexander A Officer A-Award A Stock option (right to buy) 152,300 10.71 1.63M 152,300 D
2025-01-02 Dorsey Brian Officer A-Award A Stock option (right to buy) 261,900 10.71 2.80M 261,900 D
2025-01-02 Chakma Justin Officer A-Award A Stock option (right to buy) 274,100 10.71 2.94M 274,100 D
2024-12-17 Tanimoto Sarina Officer / 10% Owner S-Sale D Common Stock 50,000 11.67 583.6K 1,297,447 I
2024-12-17 Lowenthal Richard E Director / Officer / 10% Owner S-Sale D Common Stock 50,000 11.67 583.6K 1,297,447 I
2024-12-13 Chakma Justin Officer M-Exempt A Common Stock 27,272 1.44 39.3K 163,652 D
2024-12-12 Dorsey Brian Officer S-Sale D Common Stock 25,000 12.30 307.4K 6,024 D
2024-12-12 Chakma Justin Officer M-Exempt A Common Stock 117,333 0.84 98.6K 253,713 D
2024-12-11 Dorsey Brian Officer S-Sale D Common Stock 15,000 12.43 186.4K 6,024 D
2024-12-10 Tanimoto Sarina Officer / 10% Owner S-Sale D Common Stock 50,000 13.17 658.3K 1,246,494 I
2024-12-10 Lowenthal Richard E Director / Officer / 10% Owner S-Sale D Common Stock 50,000 13.17 658.3K 1,246,494 I
2024-12-10 Chakma Justin Officer M-Exempt A Common Stock 50,000 0.84 42.0K 186,380 D
2024-12-06 Tanimoto Sarina Officer / 10% Owner M-Exempt A Common Stock 11,876 8.42 100.0K 3,433,512 D
2024-12-06 Lowenthal Richard E Director / Officer / 10% Owner M-Exempt D Stock Option (right to buy) 13,789 1.44 19.9K 20,684 I
2024-12-06 Chakma Justin Officer M-Exempt A Common Stock 50,000 0.84 42.0K 186,380 D
2024-12-05 Chakma Justin Officer M-Exempt A Common Stock 49,640 0.84 41.7K 186,020 D
2024-12-04 Shawver Laura Director M-Exempt A Common Stock 14,772 3.15 46.5K 225,118 D
2024-12-04 Karas Eric Officer M-Exempt D Stock Option (Right to Buy) 6,283 1.50 9.4K 584,588 D
2024-12-04 Chakma Justin Officer S-Sale D Common Stock 45,000 13.95 627.9K 136,380 D
2024-12-03 Shawver Laura Director M-Exempt D Stock Option (Right to Buy) 62,378 3.15 196.5K 73,836 D
2024-12-03 Chakma Justin Officer M-Exempt D Stock Option (Right to Buy) 3,260 0.84 2.7K 0 D
2024-12-02 Shawver Laura Director S-Sale D Common Stock 96,343 13.55 1.31M 211,247 D
2024-12-02 Karas Eric Officer M-Exempt A Common Stock 3,717 1.50 5.6K 9,410 D
2024-12-02 Chakma Justin Officer M-Exempt D Stock Option (Right to Buy) 45,000 0.84 37.8K 3,260 D
2024-11-27 Chakma Justin Officer S-Sale D Common Stock 25,000 14.39 359.8K 136,380 D
2024-11-26 Chakma Justin Officer S-Sale D Common Stock 42,186 14.05 592.6K 161,380 D
2024-11-25 Chakma Justin Officer S-Sale D Common Stock 32,814 14.00 459.4K 203,566 D
2024-11-19 Tanimoto Sarina Officer / 10% Owner S-Sale D Common Stock 50,000 13.95 697.5K 1,347,447 I
2024-11-19 Lowenthal Richard E Director / Officer / 10% Owner S-Sale D Common Stock 50,000 13.95 697.5K 1,347,447 I
2024-11-12 Tanimoto Sarina Officer / 10% Owner S-Sale D Common Stock 4,876 17.64 86.0K 1,248,499 I
2024-11-12 Lowenthal Richard E Director / Officer / 10% Owner S-Sale D Common Stock 4,876 17.64 86.0K 1,248,499 I
2024-11-12 Flynn James E 10% Owner S-Sale D Class A Common Stock 9,554 17.77 169.8K 5,257,329 I
2024-11-11 Flynn James E 10% Owner S-Sale D Class A Common Stock 40,596 17.45 708.4K 5,498,368 I
2024-10-16 Scott Kathleen D. Officer M-Exempt D Stock Option (Right to Buy) 12,500 1.50 18.8K 802,330 D
2024-10-15 Tanimoto Sarina Officer / 10% Owner S-Sale D Common Stock 50,000 14.88 743.8K 1,298,499 I
2024-10-15 Lowenthal Richard E Director / Officer / 10% Owner S-Sale D Common Stock 50,000 14.88 743.8K 1,298,499 I
2024-10-08 Tanimoto Sarina Officer / 10% Owner S-Sale D Common Stock 50,000 13.83 691.4K 1,348,499 I
2024-10-08 Lowenthal Richard E Director / Officer / 10% Owner S-Sale D Common Stock 50,000 13.83 691.4K 1,348,499 I
2024-09-18 Karas Eric Officer M-Exempt D Stock Option (Right to Buy) 10,000 1.50 15.0K 594,588
2024-09-17 Tanimoto Sarina Officer / 10% Owner S-Sale D Common Stock 50,000 12.93 646.7K 1,398,499
2024-09-17 Lowenthal Richard E Director / Officer / 10% Owner S-Sale D Common Stock 50,000 12.93 646.7K 1,398,499
2024-09-10 Tanimoto Sarina Officer / 10% Owner S-Sale D Common Stock 50,000 11.50 574.9K 1,448,499
2024-09-10 Lowenthal Richard E Director / Officer / 10% Owner S-Sale D Common Stock 50,000 11.50 574.9K 1,448,499
2024-08-26 Thompson Peter A. Director S-Sale D Common Stock 83,695 13.00 1.09M 0
2024-08-26 ORBIMED ADVISORS LLC Director S-Sale D Common Stock 83,695 13.00 1.09M 0
2024-08-23 Thompson Peter A. Director S-Sale D Common Stock 69,500 13.03 905.6K 83,695
2024-08-23 ORBIMED ADVISORS LLC Director S-Sale D Common Stock 69,500 13.03 905.6K 83,695
2024-08-22 Thompson Peter A. Director S-Sale D Common Stock 391,482 12.94 5.07M 153,195
2024-08-22 ORBIMED ADVISORS LLC Director S-Sale D Common Stock 391,482 12.94 5.07M 153,195
2024-08-21 Thompson Peter A. Director S-Sale D Common Stock 13,300 14.61 194.3K 544,677
2024-08-21 ORBIMED ADVISORS LLC Director S-Sale D Common Stock 394,400 13.52 5.33M 557,977
2024-08-20 Tanimoto Sarina Officer / 10% Owner S-Sale D Common Stock 36,216 14.76 534.5K 1,512,283
2024-08-20 Scott Kathleen D. Officer S-Sale D Common Stock 12,500 16.00 200.0K 13,199
2024-08-20 Lowenthal Richard E Director / Officer / 10% Owner S-Sale D Common Stock 11,523 15.62 180.0K 1,500,760
2024-08-20 Dorsey Brian Officer S-Sale D Common Stock 50,000 15.00 750.0K 6,024
2024-08-19 Karas Eric Officer M-Exempt D Stock Option (Right to Buy) 10,000 1.50 15.0K 604,588
2024-08-13 Tanimoto Sarina Officer / 10% Owner S-Sale D Common Stock 35,401 12.76 451.9K 1,446,494
2024-08-13 Lowenthal Richard E Director / Officer / 10% Owner S-Sale D Common Stock 35,401 12.76 451.9K 1,446,494
2024-08-13 Dorsey Brian Officer S-Sale D Common Stock 30,000 13.00 390.0K 6,024
2024-07-16 Tanimoto Sarina Officer / 10% Owner S-Sale D Common Stock 50,000 11.40 570.1K 1,547,447
2024-07-16 Lowenthal Richard E Director / Officer / 10% Owner S-Sale D Common Stock 50,000 11.40 570.1K 1,547,447
2024-07-09 Tanimoto Sarina Officer / 10% Owner S-Sale D Common Stock 50,000 9.62 480.8K 1,648,499
2024-07-09 Lowenthal Richard E Director / Officer / 10% Owner S-Sale D Common Stock 50,000 9.62 480.8K 1,648,499
2024-06-20 Thompson Peter A. Director A-Award A Stock Option (right to buy) 40,000 7.73 309.2K 40,000
2024-06-20 Shawver Laura Director A-Award A Stock Option (right to buy) 40,000 7.73 309.2K 40,000
2024-06-20 Shah Pratik Director A-Award A Stock Option (right to buy) 40,000 7.73 309.2K 40,000
2024-06-20 SCHNEIDER PHILLIP M Director A-Award A Stock Option (right to buy) 40,000 7.73 309.2K 40,000
2024-06-20 SAUNDERS BRENT L Director A-Award A Stock Option (right to buy) 40,000 7.73 309.2K 40,000
2024-06-20 RA CAPITAL MANAGEMENT, L.P. Director / 10% Owner A-Award A Stock Option (Right to Buy) 40,000 7.73 309.2K 40,000
2024-06-20 Kelly Michael Director A-Award A Stock Option (right to buy) 40,000 7.73 309.2K 40,000
2024-06-20 Islam Saqib Director A-Award A Stock Option (right to buy) 40,000 7.73 309.2K 40,000
2024-06-20 Dadoo Rajeev Director A-Award A Stock Option (right to buy) 40,000 7.73 309.2K 40,000
2024-06-13 Shah Pratik Director G-Gift D Common Stock 200,000 0.00 1,132,900
2024-06-12 Tanimoto Sarina Officer / 10% Owner S-Sale D Common Stock 47,834 9.15 437.5K 1,546,494
2024-06-12 Lowenthal Richard E Director / Officer / 10% Owner S-Sale D Common Stock 47,834 9.15 437.5K 1,546,494
2024-06-11 Tanimoto Sarina Officer / 10% Owner S-Sale D Common Stock 1,972 9.00 17.8K 1,746,527
2024-06-11 Lowenthal Richard E Director / Officer / 10% Owner S-Sale D Common Stock 2,166 9.00 19.5K 1,594,328
2024-06-07 Shah Pratik Director / 10% Owner G-Gift D Common Stock 1,332,950 0.00 4,824,554
2024-06-04 Shah Pratik Director / 10% Owner J-Other D Common Stock 2,665,800 0.00 7,490,404
2024-05-16 Tanimoto Sarina Officer / 10% Owner S-Sale D Common Stock 44,746 9.06 405.3K 1,597,447
2024-05-16 Lowenthal Richard E Director / Officer / 10% Owner S-Sale D Common Stock 44,746 9.06 405.3K 1,597,447
2024-05-15 Tanimoto Sarina Officer / 10% Owner S-Sale D Common Stock 2,381 9.05 21.6K 1,642,193
2024-05-15 Lowenthal Richard E Director / Officer / 10% Owner S-Sale D Common Stock 2,381 9.05 21.6K 1,642,193
2024-05-14 Tanimoto Sarina Officer / 10% Owner S-Sale D Common Stock 2,884 9.01 26.0K 1,795,615
2024-05-14 Lowenthal Richard E Director / Officer / 10% Owner S-Sale D Common Stock 2,873 9.01 25.9K 1,644,574
2024-05-07 Tanimoto Sarina Officer / 10% Owner S-Sale D Common Stock 50,000 9.34 467.2K 1,798,499
2024-05-07 Lowenthal Richard E Director / Officer / 10% Owner S-Sale D Common Stock 50,000 9.34 467.2K 1,798,499
2024-04-23 Tanimoto Sarina Officer / 10% Owner M-Exempt D Stock Option (right to buy) 48,260 1.44 69.5K 34,473
2024-04-23 Lowenthal Richard E Director / Officer / 10% Owner M-Exempt A Common Stock 48,260 1.44 69.5K 3,407,847
2024-04-19 Tanimoto Sarina Officer / 10% Owner M-Exempt A Common Stock 69,444 1.44 100.0K 4,315,313
2024-04-19 Lowenthal Richard E Director / Officer / 10% Owner M-Exempt A Common Stock 69,444 1.44 100.0K 4,315,313
2024-04-16 Tanimoto Sarina Officer / 10% Owner S-Sale D Common Stock 50,000 9.28 464.0K 1,647,447
2024-04-16 Lowenthal Richard E Director / Officer / 10% Owner S-Sale D Common Stock 50,000 9.28 464.0K 1,647,447
2024-04-09 Tanimoto Sarina Officer / 10% Owner S-Sale D Common Stock 50,000 9.28 463.9K 1,898,499
2024-04-09 Lowenthal Richard E Director / Officer / 10% Owner S-Sale D Common Stock 50,000 9.28 463.9K 1,898,499
2024-03-27 RA CAPITAL MANAGEMENT, L.P. Director / 10% Owner P-Purchase A Common Stock 505,954 9.79 4.95M 9,958,073
2024-03-26 RA CAPITAL MANAGEMENT, L.P. Director / 10% Owner P-Purchase A Common Stock 457,745 9.55 4.37M 9,452,119
2024-03-25 Tanimoto Sarina Officer / 10% Owner S-Sale D Common Stock 47,635 9.12 434.6K 1,697,447
2024-03-25 RA CAPITAL MANAGEMENT, L.P. Director / 10% Owner P-Purchase A Common Stock 437,600 9.06 3.96M 8,994,374
2024-03-25 Lowenthal Richard E Director / Officer / 10% Owner S-Sale D Common Stock 47,632 9.12 434.6K 1,948,499
2024-03-22 Tanimoto Sarina Officer / 10% Owner S-Sale D Common Stock 1,326 9.01 12.0K 1,996,131
2024-03-22 Lowenthal Richard E Director / Officer / 10% Owner S-Sale D Common Stock 1,017 9.03 9.2K 1,745,082
2024-03-21 Tanimoto Sarina Officer / 10% Owner S-Sale D Common Stock 100 9.00 900.00 1,997,457
2024-03-21 Lowenthal Richard E Director / Officer / 10% Owner S-Sale D Common Stock 100 9.00 900.00 1,997,457
2024-03-19 Tanimoto Sarina Officer / 10% Owner S-Sale D Common Stock 942 9.04 8.5K 1,997,557
2024-03-19 Lowenthal Richard E Director / Officer / 10% Owner S-Sale D Common Stock 942 9.04 8.5K 1,997,557
2024-03-15 Tanimoto Sarina Officer / 10% Owner S-Sale D Common Stock 48,295 9.14 441.5K 1,696,494
2024-03-15 Lowenthal Richard E Director / Officer / 10% Owner S-Sale D Common Stock 48,295 9.14 441.5K 1,696,494
2024-03-14 Tanimoto Sarina Officer / 10% Owner S-Sale D Common Stock 205 9.00 1.8K 1,744,789
2024-03-14 Lowenthal Richard E Director / Officer / 10% Owner S-Sale D Common Stock 205 9.00 1.8K 1,744,789
2024-03-13 Tanimoto Sarina Officer / 10% Owner S-Sale D Common Stock 1,300 9.00 11.7K 2,047,199
2024-03-13 Lowenthal Richard E Director / Officer / 10% Owner S-Sale D Common Stock 1,500 9.00 13.5K 1,744,994
2024-02-29 Tanimoto Sarina Officer / 10% Owner S-Sale D Common Stock 1,982 9.01 17.9K 2,048,499
2024-02-29 Lowenthal Richard E Director / Officer / 10% Owner S-Sale D Common Stock 1,982 9.01 17.9K 2,048,499
2024-02-28 Tanimoto Sarina Officer / 10% Owner S-Sale D Common Stock 24,303 9.02 219.2K 1,748,447
2024-02-28 Lowenthal Richard E Director / Officer / 10% Owner S-Sale D Common Stock 25,456 9.02 229.6K 1,747,294
2024-02-26 Tanimoto Sarina Officer / 10% Owner S-Sale D Common Stock 100 9.01 901.00 1,772,750
2024-02-26 Lowenthal Richard E Director / Officer / 10% Owner S-Sale D Common Stock 100 9.01 901.00 1,772,750
2024-01-02 Tanimoto Sarina Officer / 10% Owner A-Award A Stock option (right to buy) 300,000 5.58 1.67M 300,000
2024-01-02 Scott Kathleen D. Officer A-Award A Stock option (right to buy) 200,000 5.58 1.12M 200,000
2024-01-02 Lowenthal Richard E Director / Officer / 10% Owner A-Award A Stock option (right to buy) 300,000 5.58 1.67M 300,000
2024-01-02 Karas Eric Officer A-Award A Stock option (right to buy) 200,000 5.58 1.12M 200,000
2024-01-02 Fitzpatrick Alexander A Officer A-Award A Stock option (right to buy) 300,000 5.58 1.67M 300,000
2024-01-02 Dorsey Brian Officer A-Award A Stock option (right to buy) 350,000 5.58 1.95M 350,000
2024-01-02 Chakma Justin Officer A-Award A Stock option (right to buy) 350,000 5.58 1.95M 350,000
2023-09-29 Fitzpatrick Alexander A Officer P-Purchase A Common Stock 46,258 3.78 175.0K 89,227
2023-09-28 Fitzpatrick Alexander A Officer P-Purchase A Common Stock 40,000 3.62 145.0K 42,969
2023-09-21 RA CAPITAL MANAGEMENT, L.P. Director P-Purchase A Common Stock 2,508,691 2.97 7.45M 8,365,465
2023-09-01 Shawver Laura Director M-Exempt A Common Stock 97,003 1.27 123.2K 310,346
2023-08-29 Thompson Peter A. Director P-Purchase A Common Stock 500,000 6.20 3.10M 8,019,187
2023-08-29 RA CAPITAL MANAGEMENT, L.P. Director P-Purchase A Common Stock 3,750,000 6.20 23.25M 5,856,774
2023-08-29 ORBIMED ADVISORS LLC Director P-Purchase A Common Stock 500,000 6.20 3.10M 8,019,187
2023-08-04 Shawver Laura Director M-Exempt A Common Stock 18,897 1.27 24.0K 229,243
2023-08-03 Shawver Laura Director M-Exempt A Common Stock 26,107 1.27 33.2K 236,453
2023-08-02 Shawver Laura Director M-Exempt A Common Stock 36,281 1.27 46.1K 246,627
2023-08-01 Shawver Laura Director S-Sale D Common Stock 18,715 7.19 134.6K 210,346
2023-07-07 Shawver Laura Director M-Exempt D Stock Option (Right to Buy) 8,858 1.27 11.2K 102,997
2023-07-06 Shawver Laura Director M-Exempt D Stock Option (Right to Buy) 33,510 1.27 42.6K 111,855
2023-07-05 Shawver Laura Director M-Exempt D Stock Option (Right to Buy) 31,112 1.27 39.5K 145,365
2023-07-03 Shawver Laura Director M-Exempt D Stock Option (Right to Buy) 26,520 1.27 33.7K 176,477
2023-06-27 Thompson Peter A. Director / 10% Owner A-Award A Stock Option (right to buy) 40,000 6.50 260.0K 40,000
2023-06-27 Shawver Laura Director A-Award A Stock Option (right to buy) 40,000 6.50 260.0K 40,000
2023-06-27 Shah Pratik Director / 10% Owner A-Award A Stock Option (right to buy) 40,000 6.50 260.0K 40,000
2023-06-27 SCHNEIDER PHILLIP M Director A-Award A Stock Option (right to buy) 40,000 6.50 260.0K 40,000
2023-06-27 SAUNDERS BRENT L Director A-Award A Stock Option (right to buy) 40,000 6.50 260.0K 40,000
2023-06-27 RA CAPITAL MANAGEMENT, L.P. Director A-Award A Stock Option (Right to Buy) 40,000 6.50 260.0K 40,000
2023-06-27 Kelly Michael Director A-Award A Stock Option (right to buy) 40,000 6.50 260.0K 40,000
2023-06-27 Islam Saqib Director A-Award A Stock Option (right to buy) 40,000 6.50 260.0K 40,000
2023-06-27 Dadoo Rajeev Director A-Award A Stock Option (right to buy) 40,000 6.50 260.0K 40,000
2023-06-02 Shawver Laura Director M-Exempt A Common Stock 26,941 1.27 34.2K 237,287
2023-06-01 Shawver Laura Director M-Exempt A Common Stock 73,059 1.27 92.8K 283,405
2023-05-17 Tanimoto Sarina Officer / 10% Owner G-Gift A Common Stock 1,050,000 0.00 1,050,000
2023-05-17 Lowenthal Richard E Director / Officer / 10% Owner G-Gift D Common Stock 1,050,000 0.00 4,126,822
2023-05-09 Shawver Laura Director M-Exempt D Stock Option (Right to Buy) 42,900 1.27 54.5K 302,997
2023-05-08 Shawver Laura Director M-Exempt A Common Stock 57,100 1.27 72.5K 267,446
2023-01-03 Tanimoto Sarina Officer A-Award A Stock option (right to buy) 350,000 0.00 350,000
2023-01-03 Scott Kathleen D. Officer A-Award A Stock option (right to buy) 50,000 0.00 50,000
2023-01-03 Lowenthal Richard E Officer A-Award A Stock option (right to buy) 350,000 0.00 350,000
2023-01-03 Karas Eric Officer A-Award A Stock option (right to buy) 50,000 0.00 50,000
2023-01-03 Fitzpatrick Alexander A Officer A-Award A Stock option (right to buy) 700,000 0.00 700,000
2023-01-03 Dorsey Brian Officer A-Award A Stock option (right to buy) 145,000 0.00 145,000

Executive team

Top executives
EBIT / Employee
-11.6K
Shares Outstanding
99.30M

Executive compensation

Executive compensation (annual)
# Year Executive Salary Bonus Stock award Option award Incentive Other Total % Stock-
based
Filing
1 2025 Richard Lowenthal, M.S., MSEL President and Chief Executive Officer 700.0K 6.18M 315.0K 2.47M 9.66M 63.96%
2 2025 Sarina Tanimoto, M.D., M.B.A. Chief Medical Officer 540.0K 2.11M 178.2K 2.47M 5.29M 39.83%
3 2025 Justin Chakma Chief Business Officer 497.0K 2.21M 164.0K 21.7K 2.89M 76.36%
4 2024 Richard Lowenthal, M.S., MSEL President and Chief Executive Officer 651.0K 3.84M 507.8K 2.17M 7.17M 53.55%
5 2024 Sarina Tanimoto, M.D., M.B.A. Chief Medical Officer 501.7K 1.31M 260.9K 2.17M 4.25M 30.84%
CEO compensation breakdown

Proxy statements

Proxy statements (DEF 14A)
Filing date Form type Filing
2026-04-29 DEFA14A
2026-04-29 DEF 14A
2025-04-29 DEFA14A
2025-04-29 DEF 14A

Recent SEC filings

Recent SEC filings
Filing date Form type Filing
2026-05-15 SC 13G/A
2026-05-15 8-K
2026-05-15 10-Q
2026-05-13 8-K
2026-04-29 DEFA14A
2026-04-29 DEF 14A
2026-04-29 ARS
2026-04-27 SC 13G/A
2026-03-31 SC 13G/A
2026-03-24 SC 13G

Executive team

NameTitleCompensationGender
Richard Lowenthal MSMSEL Co-Founder, President, Chief Executive Officer & Director 3M male
Sarina Tanimoto Co-Founder & Chief Medical Officer 3M
Brian T. Dorsey Chief Operations Officer 707.0K male
Justin Chakma Chief Business Officer 682.7K male
Alexander A. Fitzpatrick Chief Legal Officer & Secretary 677.1K male
Eric Karas Chief Commercial Officer 618.6K male
Kathleen D. Scott Chief Financial Officer female
Lynda Harris Vice President of Human Resources female
Robert Bell Co-Founder & Chief Science Officer
Daniel Relovsky Senior Vice President of Marketing male
ESG Rating
B
BIOTECHNOLOGY
Rank: 364 out of 712
2026
E (Environmental)
58.2 / 56.3
Company / Sector avg.
S (Social)
65.4 / 62.4
Company / Sector avg.
G (Governance)
60.4 / 60.9
Company / Sector avg.
ESG Total
61.4 / 59.9
Company / Sector avg.
ESG Score History BIOTECHNOLOGY
Benchmark vs Sector
Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend history

Earnings history

Earnings reports

Stock splits