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Summit Therapeutics Inc. (SMMT)

USD15.20 -0.28 (-1.78%)
US NASDAQ Healthcare Biotechnology
Address One Broadway 2142
Cambridge, MA, US
CEO Robert W. Duggan
IPO 2015-03-05
CIK 1599298 ISIN US86627T1088

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Description

Summit Therapeutics Inc. is a biopharmaceutical firm dedicated to discovering, developing, and commercializing therapeutic solutions, primarily targeting infectious diseases across the United States and Latin America. The company's clinical development pipeline is heavily concentrated on therapies for Clostridioides difficile infection (CDI). Its flagship product candidate, ridinilazole, is an orally administered small molecule antibiotic currently advancing through Phase III clinical trials as a treatment for CDI. Beyond its lead asset, Summit Therapeutics is also progressing SMT-738, designed to combat multidrug-resistant infections, notably carbapenem-resistant Enterobacteriaceae (CRE). Additionally, its DDS-04 series represents a potential therapeutic avenue for various infections caused by the Enterobacteriaceae family of bacteria. Established in 2003, the company maintains its headquarters in Cambridge, Massachusetts.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
USD15.20 -0.28 (-1.78%)
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Volume Profile
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Liquidity & share structure
Average Volume
5M
Beta
-1.26
Float Shares
107.26M
Free Float %
13.8%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
+1.55% +5.75% -3.66% +29.53% +0.64% +8.35% -24.98% +1,001.74% +246.44% +130.82% +85.97%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
vs.
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Analyst Consensus (21 ratings, all time) Buy
Price Targets & DCF
Current price
15.20
Low 16.00 +5.3%
Consensus 19.00 +25.0%
Median 18.00 +18.5%
High 23.00 +51.4%
DCF (Unlevered) 0.25 -98.4%
DCF (Levered) 0.28 -98.2%

DCF figures are point estimates: small changes in growth or discount-rate assumptions move them materially. Read them as a reference, not a precise target.

Ratings Trend (MoM) 71% Bullish
Rating 2026-05 Change
Strong Buy 1 0
Buy 11 0
Hold 4 0
Sell 0 0
Strong Sell 1 0
Price Target Summary
Period # Analysts Avg Target
Last Month 2
19.50
+28.3%
Last Quarter 3
23.00
+51.4%
Last Year 9
24.11
+58.7%
All Time 20
28.70
+88.9%
Quality scores
Altman Z-Score
72.79
Safe zone
Piotroski F-Score
1 / 9
Weak
MOAT Score
3 / 10
No MOAT
Composite Rating
C-
Overall Score
1 / 5
Low
DCF Score
2 / 5
Medium
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
3 / 5
Medium
P/E Score
1 / 5
Low
P/Book Score
1 / 5
Low
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
  • EPS growth Biotechnology: +29.7%
    -476.0% Q1'26: -244.3% (vs Q1'25)
  • FCF margin FCF growth · Biotechnology: +16.2%
  • EBIT margin Biotechnology: +0.0%
  • ROIC Biotechnology: -16.1%
    Q1'26: +3,142.9% (vs Q1'25)
  • Share dilution Biotechnology: -3.4%
    +4.1% Q1'26: +5.1% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    -0.01× Q1'26: -0.02× (vs Q1'25)
Valuation Multiples From To
Price Forecast (3Y) From To
Model
Adjust
P/E
Theoretical Return — If Invested Today

* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.

DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (-1.26) × ERP
WACC = 100% × Ke + 0% × Kd (4.1%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Intrinsic value (base): 0.25 Current price: 15.20
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2014
actual
Dec 2015
actual
Dec 2016
actual
Dec 2017
actual
Dec 2018
actual
Dec 2019
actual
Dec 2019
actual
Dec 2020
actual
Dec 2021
actual
Dec 2023
actual
Dec 2024
actual
Dec 2025
actual
Dec 2026
9 Rev. Ana.
8 EPS Ana.
Dec 2027
10 Rev. Ana.
8 EPS Ana.
Dec 2028
12 Rev. Ana.
6 EPS Ana.
Dec 2029
11 Rev. Ana.
4 EPS Ana.
Dec 2030
6 Rev. Ana.
2 EPS Ana.
Revenue
1.84M
est: 2.82M (-34.5%)
1.89M
est: 2.10M (-10.2%)
1.28M
est: 1.96M (-34.7%)
2.38M
est: 35.88M (-93.4%)
14.17M
est: 73.68M (-80.8%)
57.09M
est: 19.43M (+193.9%)
611.9K
est: 19.43M (-96.9%)
628.9K
est: 19.16M (-96.7%)
1.34M
est: 1.60M (-16.4%)
est: 966.0K (-100.0%)
est: 12.31M (-100.0%)
est: 42.76M (-100.0%)
7.25M
2.59M – 14.01M
-83.0% YoY
100.64M
63.05M – 138.46M
+1,287.9% YoY
931.98M
895.58M – 968.38M
+826.1% YoY
2.44B
1.49B – 3.44B
+162.1% YoY
4.35B
2.65B – 6.13B
+78.0% YoY
EBITDA
-6.68M
est: -563.4K (-1,086.1%)
-12.20M
est: -420.4K (-2,801.7%)
-20.30M
est: -392.2K (-5,075.4%)
-24.80M
est: -7.18M (-245.6%)
-26.34M
est: -14.74M (-78.7%)
11.66M
est: -3.89M (+400.0%)
-21.56M
est: -3.89M (-455.0%)
-37.13M
est: -3.83M (-869.3%)
-62.74M
est: -320.0K (-19,505.0%)
-69.45M
est: -193.2K (-35,847.9%)
-168.46M
est: 2.46M (-6,942.2%)
-1.08B
est: 8.55M (-12,722.7%)
1.45M
518.9K – 2.80M
-83.0% YoY
20.13M
12.61M – 27.69M
+1,287.9% YoY
186.40M
179.12M – 193.68M
+826.1% YoY
488.58M
298.22M – 688.50M
+162.1% YoY
869.59M
530.77M – 1.23B
+78.0% YoY
EBIT
-6.71M
est: -563.4K (-1,090.7%)
-12.23M
est: -420.4K (-2,809.5%)
-20.35M
est: -392.2K (-5,087.7%)
-24.85M
est: -7.18M (-246.4%)
-26.74M
est: -14.74M (-81.5%)
9.70M
est: -3.89M (+349.7%)
-22.62M
est: -3.89M (-482.3%)
-38.27M
est: -3.83M (-898.9%)
-63.73M
est: -320.0K (-19,816.3%)
-69.61M
est: -193.2K (-35,928.3%)
-168.53M
est: 2.46M (-6,945.1%)
-1.08B
est: 8.55M (-12,724.4%)
1.45M
518.9K – 2.80M
-83.0% YoY
20.13M
12.61M – 27.69M
+1,287.9% YoY
186.40M
179.12M – 193.68M
+826.1% YoY
488.58M
298.22M – 688.50M
+162.1% YoY
869.59M
530.77M – 1.23B
+78.0% YoY
Net Income
-6.09M
est: -1.66B (+99.6%)
-11.38M
est: -1.55B (+99.3%)
-20.14M
est: -1.59B (+98.7%)
-21.37M
est: -150.71M (+85.8%)
-20.16M
est: 351.47M (-105.7%)
10.87M
est: -245.43M (+104.4%)
-23.99M
est: -245.43M (+90.2%)
-38.53M
est: -574.83M (+93.3%)
-65.52M
est: -689.80M (+90.5%)
-482.37M
est: -431.13M (-11.9%)
-176.77M
est: -283.79M (+37.7%)
-1.08B
est: -738.96M (-46.1%)
-917.42M
-1.00B – -727.03M
-24.1% YoY
-897.50M
-1.02B – -754.26M
+2.2% YoY
-49.79M
-3.34B – 6.14B
+94.5% YoY
554.13M
273.45M – 848.88M
+1,212.8% YoY
1.56B
769.92M – 2.39B
+181.6% YoY
SGA
1.94M
est: 42.44M (-95.4%)
3.70M
est: 31.67M (-88.3%)
4.77M
est: 29.54M (-83.9%)
8.28M
est: 540.48M (-98.5%)
11.94M
est: 1.11B (-98.9%)
17.01M
est: 292.65M (-94.2%)
9.29M
est: 292.65M (-96.8%)
14.06M
est: 288.59M (-95.1%)
17.46M
est: 24.10M (-27.6%)
23.74M
est: 14.55M (+63.1%)
48.35M
est: 132.91M (-63.6%)
556.70M
est: 461.64M (+20.6%)
78.29M
28.01M – 151.26M
-83.0% YoY
1.09B
680.73M – 1.49B
+1,287.9% YoY
10.06B
9.67B – 10.46B
+826.1% YoY
26.38B
16.10B – 37.17B
+162.1% YoY
46.95B
28.65B – 66.15B
+78.0% YoY
EPS
-0.30
est: -2.31 (+87.0%)
-0.29
est: -2.15 (+86.5%)
-0.34
est: -2.21 (+84.6%)
-0.35
est: -0.21 (-66.9%)
-0.31
est: 0.49 (-163.4%)
0.11
est: -0.34 (+132.2%)
-0.73
est: -0.34 (-113.7%)
-0.55
est: -0.80 (+31.3%)
-0.71
est: -0.96 (+26.0%)
-0.78
est: -0.60 (-30.0%)
-0.25
est: -0.38 (+34.1%)
-1.44
est: -1.11 (-29.3%)
-1.10
-1.34 – -0.97
+0.8% YoY
-1.12
-1.36 – -1.01
-1.4% YoY
-0.29
-4.47 – 8.21
+74.5% YoY
0.74
0.37 – 1.14
+359.8% YoY
2.09
1.03 – 3.20
+181.6% YoY
Recent Grade Changes (3M)
Date Firm Previous New Grade Action
2026-05-04 HC Wainwright & Co. Buy Buy Maintain
2026-05-01 Piper Sandler Neutral Neutral Maintain
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-11 C- 1/5 2/5 1/5 1/5 3/5 1/5 1/5
2026-05-08 C- 1/5 2/5 1/5 1/5 3/5 1/5 1/5
2026-05-07 C- 1/5 2/5 1/5 1/5 3/5 1/5 1/5
2026-05-06 C- 1/5 2/5 1/5 1/5 3/5 1/5 1/5
2026-05-05 C- 1/5 2/5 1/5 1/5 3/5 1/5 1/5
2026-05-04 C- 1/5 2/5 1/5 1/5 3/5 1/5 1/5
2026-05-01 C- 1/5 2/5 1/5 1/5 3/5 1/5 1/5
2026-04-30 C- 1/5 2/5 1/5 1/5 3/5 1/5 1/5
2026-04-29 C- 1/5 2/5 1/5 1/5 3/5 1/5 1/5
2026-04-28 C- 1/5 2/5 1/5 1/5 3/5 1/5 1/5
2026-04-27 C- 1/5 2/5 1/5 1/5 2/5 1/5 1/5
2026-04-24 C- 1/5 2/5 1/5 1/5 2/5 1/5 1/5
2026-04-23 C- 1/5 3/5 1/5 1/5 2/5 1/5 1/5
2026-04-22 C- 1/5 3/5 1/5 1/5 2/5 1/5 1/5
2026-04-21 C- 1/5 3/5 1/5 1/5 2/5 1/5 1/5
2026-04-20 C- 1/5 3/5 1/5 1/5 2/5 1/5 1/5
2026-04-17 C- 1/5 3/5 1/5 1/5 2/5 1/5 1/5
2026-04-16 C- 1/5 3/5 1/5 1/5 2/5 1/5 1/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
-384.05M
OE per share TTM
-0.51
Owner's Yield
-2.65%
Maintenance CapEx ratio
Maint CapEx / Avg PPE
1,153.0%

Ownership Overview

Ownership breakdown
At a glance
Institutional holders
62
Total invested
104.57M
Insider transactions (90d)
0
Beneficial owners (>5%)
9
Beneficial owners (>5%)
# Reporting person Amount owned % of class Sole voting Shared voting Sole dispositive Shared dispositive Type Citizenship Filing date SEC filing
1 ROBERT W. DUGGAN 46.21M 64.89% 46.21M 10.00 IN 2020-09-28
2 Polar Capital Holdings Plc 5.80M 7.05% 5.80M HC United Kingdom 2021-02-16
3 Polar Capital LLP 5.80M 7.05% 5.80M IA United Kingdom 2021-02-16
4 MAHKAM ZANGANEH 5.33M 7.80% 489.8K 4.84M IN 2020-09-28
5 Point72 Asset Management, L.P. 3.86M 6.60% 3.86M PN Delaware 2015-03-11
6 Point72 Capital Advisors, Inc. 3.86M 6.60% 3.86M CO Delaware 2015-03-11
7 Steven A. Cohen 3.86M 6.60% 3.86M IN Delaware 2015-03-11
8 MAHKAM ZANGANEH REVOCABLE TRUST 2.42M 3.58% 2.42M OO 2020-09-28
9 SHAUN ZANGANEH IRREVOCABLE TRUST 2.42M 3.58% 2.42M OO 2020-09-28

Institutional Activity (13F)

Institutional ownership trend From To
13F snapshot — 2026 Q1
Investors holding
62
-160 vs prev Q
New positions
16
Closed positions
166
Increased
37
Reduced
12
Put/Call ratio
0.00
Calls held
Puts held
Top institutional holders
# Investor Shares / Δ Mkt value / Δ Own% / Δ Weight% / Δ Avg px / Perf. Hold / Status
1 BAKER BROS. ADVISORS LP 36.39M +2.7M (+7.9%) 636.48M -60.2M (-8.6%) 4.90% +0.354 pp 3.73% -1.308 pp USD12.64 +38.4% 7 qtrs
2 FMR LLC 13.36M +4.4M (+49.8%) 233.68M +49.4M (+26.8%) 1.80% +0.596 pp 0.01% +0.002 pp USD10.79 +62.1% 11 qtrs
3 VANGUARD GROUP INC 11.18M -202.5K (-1.8%) 195.49M -39.6M (-16.9%) 1.50% -0.029 pp 0.00% -0.001 pp USD11.08 +57.9% 21 qtrs
4 PRICE T ROWE ASSOCIATES INC /MD/ 9.37M +4.8M (+106.5%) 163.91M +70.1M (+74.8%) 1.26% +0.649 pp 0.02% +0.008 pp USD17.46 +0.2% 11 qtrs
5 BLACKROCK, INC. 9.36M +2.0M (+27.1%) 163.74M +11.6M (+7.6%) 1.26% +0.268 pp 0.00% +0.000 pp USD20.77 -15.8% 6 qtrs
6 STATE STREET CORP 6.64M +274.4K (+4.3%) 116.07M -15.4M (-11.7%) 0.89% +0.036 pp 0.00% -0.001 pp USD13.47 +29.8% 13 qtrs
7 GEODE CAPITAL MANAGEMENT, LLC 3.15M +14.7K (+0.5%) 55.06M -9.7M (-14.9%) 0.42% +0.002 pp 0.00% -0.001 pp USD5.20 +236.3% 22 qtrs
8 SUSQUEHANNA INTERNATIONAL GROUP, LLP 1.80M +411.0K (+29.5%) 31.53M +2.8M (+9.7%) 0.24% +0.055 pp 0.00% +0.000 pp USD19.37 -9.7% 13 qtrs
9 POLYMER CAPITAL MANAGEMENT (HK) LTD 1.42M +603.9K (+73.9%) 24.86M +8.0M (+47.2%) 0.19% +0.081 pp 3.54% +1.208 pp USD18.96 -7.8% 5 qtrs
10 PICTET ASSET MANAGEMENT HOLDING SA 1.38M -220.4K (-13.7%) 24.38M -9.1M (-27.2%) 0.19% -0.030 pp 0.02% -0.009 pp USD16.00 +9.3% 8 qtrs
11 NORGES BANK 1.37M +1.4M (+100.0%) 24.03M +24.0M (+100.0%) 0.18% +0.185 pp 0.00% +0.003 pp USD17.49 +0.0% 1 qtrs NEW
12 APEIRON CAPITAL LTD 1.31M -1.7K (-0.1%) 22.90M -4.2M (-15.5%) 0.18% 0.000 pp 26.48% +13.611 pp USD21.23 -17.6% 3 qtrs
13 TD ASSET MANAGEMENT INC 1.21M +667.7K (+124.2%) 21.08M +10.0M (+89.8%) 0.16% +0.090 pp 0.02% +0.008 pp USD17.36 +0.7% 7 qtrs
14 ABRDN PLC 927.2K -212.4K (-18.6%) 16.22M -7.3M (-31.1%) 0.12% -0.029 pp 0.03% -0.012 pp USD21.42 -18.3% 6 qtrs
15 MORGAN STANLEY 926.6K -1.0M (-51.9%) 16.21M -23.6M (-59.3%) 0.12% -0.135 pp 0.00% -0.001 pp USD18.16 -3.7% 22 qtrs
16 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 892.6K +16.2K (+1.9%) 15.61M -2.5M (-13.8%) 0.12% +0.002 pp 0.00% -0.001 pp USD9.52 +83.7% 13 qtrs
17 UBS GROUP AG 870.7K -408.1K (-31.9%) 15.23M -11.2M (-42.4%) 0.12% -0.055 pp 0.00% -0.002 pp USD18.43 -5.1% 22 qtrs
18 SQUAREPOINT OPS LLC 715.4K +605.6K (+551.4%) 12.51M +10.2M (+451.5%) 0.10% +0.081 pp 0.01% +0.011 pp USD18.07 -3.2% 8 qtrs
19 ROCK SPRINGS CAPITAL MANAGEMENT LP 710.0K +— (+0.0%) 12.42M -2.3M (-15.3%) 0.10% 0.000 pp 0.64% -0.220 pp USD21.85 -20.0% 6 qtrs
20 TWO SIGMA INVESTMENTS, LP 578.2K +553.2K (+2,210.2%) 10.11M +9.6M (+1,855.7%) 0.08% +0.074 pp 0.01% +0.014 pp USD17.63 -0.8% 2 qtrs
21 NOMURA HOLDINGS INC 542.2K -506.7K (-48.3%) 9.48M -12.2M (-56.2%) 0.07% -0.068 pp 0.01% -0.021 pp USD20.69 -15.5% 3 qtrs
22 CANDRIAM S.C.A. 540.7K +26.9K (+5.2%) 9.46M -1.2M (-10.9%) 0.07% +0.004 pp 0.05% -0.009 pp USD21.68 -19.3% 6 qtrs
23 NORTHERN TRUST CORP 528.5K -17.8K (-3.3%) 9.24M -2.0M (-18.1%) 0.07% -0.003 pp 0.00% 0.000 pp USD3.22 +443.2% 19 qtrs
24 GOLDMAN SACHS GROUP INC 485.6K -12.0K (-2.4%) 8.49M -1.8M (-17.4%) 0.07% -0.002 pp 0.00% 0.000 pp USD14.66 +19.3% 21 qtrs
25 BANK OF AMERICA CORP /DE/ 477.4K -179.9K (-27.4%) 8.35M -5.2M (-38.5%) 0.06% -0.024 pp 0.00% 0.000 pp USD13.14 +33.1% 22 qtrs
26 MILLENNIUM MANAGEMENT LLC 469.0K +348.5K (+289.2%) 8.20M +5.7M (+229.5%) 0.06% +0.047 pp 0.00% +0.002 pp USD16.09 +8.7% 7 qtrs
27 INVESCO LTD. 461.3K +35.2K (+8.3%) 8.07M -734.6K (-8.3%) 0.06% +0.005 pp 0.00% 0.000 pp USD15.78 +10.8% 12 qtrs
28 MANUFACTURERS LIFE INSURANCE COMPANY, THE 441.0K +141.4K (+47.2%) 7.71M +1.5M (+24.6%) 0.06% +0.019 pp 0.01% +0.001 pp USD15.35 +13.9% 11 qtrs
29 LMR PARTNERS LLP 424.4K +15.3K (+3.7%) 7.42M -1.0M (-12.2%) 0.06% +0.002 pp 0.01% -0.023 pp USD19.09 -8.4% 7 qtrs
30 TUDOR INVESTMENT CORP ET AL 423.1K +75.8K (+21.8%) 7.40M +225.7K (+3.1%) 0.06% +0.010 pp 0.01% +0.001 pp USD20.09 -12.9% 2 qtrs
31 CITADEL ADVISORS LLC 417.5K -308.9K (-42.5%) 7.30M -7.7M (-51.3%) 0.06% -0.042 pp 0.00% -0.001 pp USD20.18 -13.3% 9 qtrs
32 D. E. SHAW & CO., INC. 415.3K +284.7K (+217.9%) 7.26M +4.6M (+169.1%) 0.06% +0.038 pp 0.00% +0.003 pp USD18.66 -6.3% 7 qtrs
33 DIMENSIONAL FUND ADVISORS LP 376.6K +2.0K (+0.5%) 6.59M -1.2M (-14.9%) 0.05% +0.000 pp 0.00% 0.000 pp USD19.47 -10.2% 6 qtrs
34 QVT FINANCIAL LP 360.5K +— (+0.0%) 6.31M -1.1M (-15.3%) 0.05% 0.000 pp 0.54% +0.015 pp USD8.14 +114.9% 7 qtrs
35 SCULPTOR CAPITAL LP 356.9K +23.4K (+7.0%) 6.24M -647.9K (-9.4%) 0.05% +0.003 pp 0.06% -0.017 pp USD20.45 -14.5% 2 qtrs
36 AQR CAPITAL MANAGEMENT LLC 357.9K +170.4K (+90.9%) 6.19M +2.3M (+59.9%) 0.05% +0.023 pp 0.00% +0.001 pp USD18.48 -5.4% 7 qtrs
37 BANK OF NEW YORK MELLON CORP 353.8K -13.4K (-3.6%) 6.19M -1.4M (-18.4%) 0.05% -0.002 pp 0.00% 0.000 pp USD7.71 +126.8% 13 qtrs
38 AFFINITY ASSET ADVISORS, LLC 350.0K +— (+0.0%) 6.12M -1.1M (-15.3%) 0.05% 0.000 pp 0.35% -0.281 pp USD20.66 -15.3% 2 qtrs
39 BARCLAYS PLC 338.4K +88.3K (+35.3%) 5.92M +440.9K (+8.0%) 0.05% +0.012 pp 0.00% +0.000 pp USD11.27 +55.2% 16 qtrs
40 SKANDINAVISKA ENSKILDA BANKEN AB (PUBL) 338.4K +— (+0.0%) 5.91M -1.1M (-15.4%) 0.05% +0.000 pp 0.02% -0.004 pp USD20.25 -13.6% 5 qtrs
41 READYSTATE ASSET MANAGEMENT LP 306.2K +306.2K (+100.0%) 5.36M +5.4M (+100.0%) 0.04% +0.041 pp 0.22% +0.217 pp USD17.49 +0.0% 3 qtrs
42 RAFFERTY ASSET MANAGEMENT, LLC 287.8K -51.4K (-15.1%) 5.03M -2.0M (-28.2%) 0.04% -0.007 pp 0.02% -0.005 pp USD16.19 +8.0% 8 qtrs
43 JANE STREET GROUP, LLC 280.0K -129.7K (-31.7%) 4.90M -3.6M (-42.1%) 0.04% -0.018 pp 0.00% -0.001 pp USD21.15 -17.3% 6 qtrs
44 SCHRODER INVESTMENT MANAGEMENT GROUP 251.4K +8.8K (+3.6%) 4.40M -737.0K (-14.4%) 0.03% +0.001 pp 0.00% -0.001 pp USD19.76 -11.5% 4 qtrs
45 CAPTION MANAGEMENT, LLC 240.0K +34.5K (+16.8%) 4.20M -48.0K (-1.1%) 0.03% +0.005 pp 0.03% -0.004 pp USD20.54 -14.8% 4 qtrs
46 DEUTSCHE BANK AG\ 237.8K -32.1K (-11.9%) 4.16M -1.4M (-25.4%) 0.03% -0.004 pp 0.00% -0.001 pp USD19.28 -9.3% 11 qtrs
47 NUVEEN, LLC 232.6K +— (+0.0%) 4.07M -737.5K (-15.3%) 0.03% +0.000 pp 0.00% 0.000 pp USD19.60 -10.8% 4 qtrs
48 VERITION FUND MANAGEMENT LLC 229.0K +63.4K (+38.3%) 4.01M +583.7K (+17.1%) 0.03% +0.009 pp 0.02% +0.002 pp USD20.23 -13.5% 6 qtrs
49 WOODLINE PARTNERS LP 214.5K +— (+0.0%) 3.75M -680.0K (-15.3%) 0.03% +0.000 pp 0.01% -0.006 pp USD21.19 -17.5% 3 qtrs
50 GRIFFIN ASSET MANAGEMENT, INC. 195.5K +55.3K (+39.4%) 3.42M +521.9K (+18.0%) 0.03% +0.007 pp 0.37% +0.044 pp USD19.54 -10.5% 6 qtrs
51 WELLS FARGO & COMPANY/MN 130.9K -62.0K (-32.1%) 2.29M -1.7M (-42.6%) 0.02% -0.008 pp 0.00% 0.000 pp USD17.78 -1.6% 22 qtrs
52 CITIGROUP INC 129.9K -29.9K (-18.7%) 2.27M -1.0M (-31.2%) 0.02% -0.004 pp 0.00% -0.001 pp USD16.81 +4.0% 22 qtrs
53 RHUMBLINE ADVISERS 121.3K -1.6K (-1.3%) 2.12M -417.3K (-16.4%) 0.02% 0.000 pp 0.00% 0.000 pp USD4.09 +327.6% 11 qtrs
54 CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD. 121.3K -8.9K (-6.8%) 2.12M -568.5K (-21.1%) 0.02% -0.001 pp 0.16% -0.059 pp USD11.59 +50.9% 14 qtrs
55 CAPITAL FUND MANAGEMENT S.A. 113.4K +39.2K (+52.9%) 1.98M +451.2K (+29.5%) 0.02% +0.005 pp 0.01% +0.002 pp USD19.56 -10.6% 2 qtrs
56 CERITY PARTNERS LLC 112.9K -1.8K (-1.6%) 1.97M -394.6K (-16.7%) 0.02% 0.000 pp 0.00% -0.001 pp USD21.40 -18.3% 6 qtrs
57 VOYA INVESTMENT MANAGEMENT LLC 112.4K -90.2K (-44.5%) 1.97M -2.2M (-53.0%) 0.02% -0.012 pp 0.00% -0.002 pp USD7.30 +139.6% 11 qtrs
58 PROFUND ADVISORS LLC 103.8K +33.8K (+48.4%) 1.81M +370.0K (+25.6%) 0.01% +0.005 pp 0.06% +0.008 pp USD16.56 +5.6% 8 qtrs
59 CENTIVA CAPITAL, LP 100.0K -111.2K (-52.7%) 1.75M -2.6M (-59.9%) 0.01% -0.015 pp 0.01% -0.027 pp USD21.25 -17.7% 3 qtrs
60 JEFFERIES FINANCIAL GROUP INC. 100.0K +85.0K (+566.7%) 1.75M +1.4M (+464.4%) 0.01% +0.011 pp 0.01% +0.008 pp USD17.97 -2.7% 2 qtrs
61 ILLINOIS MUNICIPAL RETIREMENT FUND 99.4K +30.7K (+44.7%) 1.74M +319.1K (+22.5%) 0.01% +0.004 pp 0.02% +0.004 pp USD19.87 -12.0% 3 qtrs
62 HSBC HOLDINGS PLC 98.8K +98.8K (+100.0%) 1.72M +1.7M (+100.0%) 0.01% +0.013 pp 0.00% +0.001 pp USD17.49 +0.0% 1 qtrs NEW
63 NEOS INVESTMENT MANAGEMENT LLC 97.2K +16.9K (+21.1%) 1.70M +41.7K (+2.5%) 0.01% +0.002 pp 0.01% -0.003 pp USD18.82 -7.1% 5 qtrs
64 STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 96.0K +— (+0.0%) 1.68M -304.3K (-15.3%) 0.01% +0.000 pp 0.00% -0.001 pp USD16.82 +4.0% 11 qtrs
65 TEMA ETFS LLC 95.8K +15.5K (+19.3%) 1.68M +16.6K (+1.0%) 0.01% +0.002 pp 0.13% -0.008 pp USD18.84 -7.2% 5 qtrs
66 BANK OF MONTREAL /CAN/ 95.4K -2.6K (-2.7%) 1.67M -357.0K (-17.6%) 0.01% 0.000 pp 0.00% 0.000 pp USD20.48 -14.6% 9 qtrs
67 STATE OF WISCONSIN INVESTMENT BOARD 92.9K +1.0K (+1.1%) 1.62M -272.8K (-14.4%) 0.01% +0.000 pp 0.00% -0.001 pp USD20.62 -15.2% 11 qtrs
68 ADAR1 CAPITAL MANAGEMENT, LLC 91.9K -11.1K (-10.8%) 1.61M -520.6K (-24.5%) 0.01% -0.002 pp 0.12% -0.082 pp USD20.73 -15.6% 3 qtrs
69 COLONY GROUP, LLC 88.4K +29.0 (+0.0%) 1.55M -279.6K (-15.3%) 0.01% +0.000 pp 0.00% -0.001 pp USD21.86 -20.0% 6 qtrs
70 DARK FOREST CAPITAL MANAGEMENT LP 87.1K -25.1K (-22.4%) 1.52M -795.2K (-34.3%) 0.01% -0.003 pp 0.07% +0.000 pp USD20.66 -15.3% 4 qtrs
71 AXQ CAPITAL, LP 81.5K +64.1K (+366.7%) 1.43M +1.1M (+295.1%) 0.01% +0.009 pp 0.32% +0.183 pp USD18.17 -3.7% 2 qtrs
72 UBS ASSET MANAGEMENT AMERICAS INC 79.6K +37.0 (+0.0%) 1.39M -251.7K (-15.3%) 0.01% +0.000 pp 0.00% 0.000 pp USD21.28 -17.8% 3 qtrs
73 SECTORAL ASSET MANAGEMENT INC 79.6K +5.6K (+7.5%) 1.39M -137.6K (-9.0%) 0.01% +0.001 pp 1.12% +0.172 pp USD14.74 +18.7% 12 qtrs
74 POLIANTA LTD 74.7K +— (+0.0%) 1.31M -237.0K (-15.4%) 0.01% +0.000 pp 0.17% -0.465 pp USD19.55 -10.5% 4 qtrs
75 MARINER, LLC 73.5K -6.1K (-7.6%) 1.29M -358.5K (-21.8%) 0.01% -0.001 pp 0.00% -0.001 pp USD20.75 -15.7% 3 qtrs
76 JPMORGAN CHASE & CO 67.4K -69.2K (-50.7%) 1.18M -1.6M (-58.2%) 0.01% -0.009 pp 0.00% 0.000 pp USD15.17 +15.3% 22 qtrs
77 DNB ASSET MANAGEMENT AS 61.1K +30.1K (+97.5%) 1.07M +429.1K (+67.2%) 0.01% +0.004 pp 0.00% +0.001 pp USD19.30 -9.4% 6 qtrs
78 AQUATIC CAPITAL MANAGEMENT LLC 59.9K +59.9K (+100.0%) 1.05M +1.0M (+100.0%) 0.01% +0.008 pp 0.03% +0.030 pp USD17.49 +0.0% 1 qtrs NEW
79 ASSENAGON ASSET MANAGEMENT S.A. 59.6K +59.6K (+100.0%) 1.04M +1.0M (+100.0%) 0.01% +0.008 pp 0.00% +0.001 pp USD17.49 +0.0% 1 qtrs NEW
80 WEALTH MANAGEMENT PARTNERS, LLC 59.4K -15.1K (-20.3%) 1.04M -501.2K (-32.5%) 0.01% -0.002 pp 0.30% -0.193 pp USD13.60 +28.6% 9 qtrs
81 FARTHER FINANCE ADVISORS, LLC 57.3K +2.0K (+3.7%) 1.00M -139.3K (-12.2%) 0.01% +0.000 pp 0.01% -0.007 pp USD20.55 -14.9% 2 qtrs
82 AMERIPRISE FINANCIAL INC 54.0K +500.0 (+0.9%) 944.7K -160.9K (-14.6%) 0.01% +0.000 pp 0.00% +0.000 pp USD19.33 -9.5% 5 qtrs
83 NEW YORK STATE COMMON RETIREMENT FUND 53.8K -210.5K (-79.7%) 940.6K -4.5M (-82.8%) 0.01% -0.028 pp 0.00% -0.006 pp USD19.44 -10.0% 11 qtrs
84 POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY 52.6K +114.0 (+0.2%) 920.3K -164.4K (-15.2%) 0.01% +0.000 pp 0.01% -0.001 pp USD19.88 -12.0% 5 qtrs
85 BALYASNY ASSET MANAGEMENT L.P. 50.3K -144.6K (-74.2%) 879.7K -3.1M (-78.1%) 0.01% -0.020 pp 0.00% -0.004 pp USD20.66 -15.3% 7 qtrs
86 GUGGENHEIM CAPITAL LLC 49.8K +8.8K (+21.5%) 871.0K +24.0K (+2.8%) 0.01% +0.001 pp 0.01% +0.000 pp USD18.16 -3.7% 5 qtrs
87 TREASURER OF THE STATE OF NORTH CAROLINA 48.9K -3.6K (-6.8%) 856.0K -229.0K (-21.1%) 0.01% -0.001 pp 0.00% -0.001 pp USD21.28 -17.8% 3 qtrs
88 WORLDQUANT MILLENNIUM ADVISORS LLC 41.7K +41.7K (+100.0%) 729.9K +729.9K (+100.0%) 0.01% +0.006 pp 0.00% +0.003 pp USD17.49 +0.0% 1 qtrs NEW
89 BEACON POINTE ADVISORS, LLC 39.6K +3.9K (+10.9%) 692.8K -45.3K (-6.1%) 0.01% +0.001 pp 0.00% -0.001 pp USD20.35 -14.1% 2 qtrs
90 MIRAE ASSET GLOBAL INVESTMENTS CO., LTD. 38.0K +7.4K (+24.2%) 664.5K +32.5K (+5.1%) 0.01% +0.001 pp 0.00% 0.000 pp USD10.54 +65.9% 12 qtrs
91 LEVIN CAPITAL STRATEGIES, L.P. 37.7K +1.0K (+2.7%) 659.0K -98.8K (-13.0%) 0.01% +0.000 pp 0.06% -0.012 pp USD6.43 +172.0% 20 qtrs
92 HANDELSBANKEN FONDER AB 37.6K +3.4K (+9.9%) 658.0K -49.0K (-6.9%) 0.01% +0.001 pp 0.00% 0.000 pp USD12.41 +40.9% 7 qtrs
Ownership breakdown by holder

ETF Ownership

Top ETFs holding this stock Held by 96 ETFs in our universe
# ETF Weight Est. AUM exposure TER
1 BMO Equal Weight US Health Care Hedged to CAD Index ETF ZUH.TO 1.17% 1.47M 0.39%
2 Global X - S&P Biotech ETF CURE.AX 1.05% 378.4K 0.45%
3 State Street SPDR S&P Biotech ETF XBI 1.05% 113.97M 0.35%
4 Tema Oncology ETF CANC 0.96% 1.37M 0.75%
5 iShares Nasdaq US Biotechnology UCITS ETF BTEC.L 0.82% 8.97M 0.35%
6 iShares Nasdaq US Biotechnology UCITS ETF BTEE.L 0.82% 600.5K 0.35%
7 Invesco Nasdaq Biotechnology ETF IBBQ 0.82% 610.4K 0.19%
8 Invesco NASDAQ Biotech UCITS ETF SBIO.L 0.82% 3.77M 0.40%
9 Virtus Biotech Clinical Trials ETF BBC 0.67% 385.7K 0.65%
10 ProShares Ultra Nasdaq Biotechnology BIB 0.46% 396.1K 1.19%

Insider Activity

Insider Activity — Latest Quarter
Ratio by transactions
0.00
Bearish
Buys
9
Sells
0
Shares acquired
29.16M
Shares disposed
Cash buys
3.00
Cash sales
Net activity
+29,162,212
Insider buys vs sells (history) From To
Recent insider transactions From To
Date Person Role Transaction A/D Security Shares Price Value Owned after D/I Filing
2026-01-08 Anand Bhaskar Officer A-Award A Stock Option (right to buy) 30,000 18.83 564.9K 30,000 D
2026-01-02 Zanganeh Mahkam Director / Officer / 10% Owner A-Award A Stock Option (right to buy) 11,232 17.52 196.8K 11,232 I
2026-01-02 Xia Yu Director A-Award A Stock Option (right to buy) 35,000 17.52 613.2K 35,000 D
2026-01-02 Ronaghi Mostafa Director A-Award A Stock Option (right to buy) 35,000 17.52 613.2K 35,000 D
2026-01-02 Huber Jeff Director A-Award A Stock Option (right to buy) 35,000 17.52 613.2K 35,000 D
2026-01-02 DUGGAN ROBERT W Director / Officer / 10% Owner A-Award A Stock Option (right to buy) 11,232 17.52 196.8K 11,232 D
2026-01-02 Clark Kenneth A Director A-Award A Stock Option (right to buy) 17,796 17.52 311.8K 17,796 D
2026-01-02 Cesano Alessandra Director A-Award A Stock Option (right to buy) 35,000 17.52 613.2K 35,000 D
2026-01-02 Booth Robert F. Director A-Award A Stock Option (right to buy) 35,000 17.52 613.2K 35,000 D
2025-10-21 Zanganeh Mahkam Director / Officer / 10% Owner P-Purchase A Common Stock 26,680 18.74 500.0K 76,680 I
2025-10-21 Xia Yu Director P-Purchase A Common Stock 533,617 18.74 10.00M 32,057,147 I
2025-10-21 Soni Manmeet Singh Director / Officer A-Award A Common Stock 53,361 18.74 1,000.0K 3,073,603 D
2025-10-21 DUGGAN ROBERT W Director / Officer / 10% Owner A-Award A Common Stock 266,808 18.74 5.00M 25,724,474 I
2025-10-21 Anand Bhaskar Officer A-Award A Common Stock 26,680 18.74 500.0K 159,751 D
2025-09-18 Anand Bhaskar Officer A-Award A Stock Option (right to buy) 50,000 19.23 961.5K 50,000 D
2025-09-11 Zanganeh Mahkam Director / Officer / 10% Owner P-Purchase A Common Stock 5,000 18.07 90.4K 556,093,090 I
2025-09-11 DUGGAN ROBERT W Director / Officer / 10% Owner P-Purchase A Common Stock 5,000 18.07 90.4K 556,093,090 D
2025-09-10 Zanganeh Mahkam Director / Officer / 10% Owner P-Purchase A Common Stock 333,394 17.68 5.89M 556,088,090 I
2025-09-10 DUGGAN ROBERT W Director / Officer / 10% Owner P-Purchase A Common Stock 333,394 17.68 5.89M 556,088,090 D
2025-05-30 Zanganeh Mahkam Director / Officer / 10% Owner M-Exempt D Stock Option (right to buy) 74,545 2.64 196.8K 0 I
2025-05-30 DUGGAN ROBERT W Director / Officer / 10% Owner M-Exempt A Common Stock 74,545 2.64 196.8K 555,754,696 D
2025-04-29 Zanganeh Mahkam Director / Officer / 10% Owner A-Award A Stock Option (right to buy) 1,040,000 1.06 1.10M 1,040,000 D
2025-04-29 Soni Manmeet Singh Director / Officer A-Award A Stock Option (right to buy) 11,200,000 1.68 18.82M 11,200,000 D
2025-04-29 DUGGAN ROBERT W Director / Officer / 10% Owner A-Award A Stock Option (right to buy) 1,040,000 1.06 1.10M 1,040,000 I
2025-04-29 Anand Bhaskar Officer A-Award A Stock Option (right to buy) 75,000 17.85 1.34M 75,000 D
2025-04-08 Zanganeh Mahkam Director / Officer / 10% Owner X-InTheMoney A Common Stock 3,985,055 1.58 6.30M 555,680,151 I
2025-04-08 DUGGAN ROBERT W Director / Officer / 10% Owner X-InTheMoney A Common Stock 3,985,055 1.58 6.30M 555,680,151 D
2025-01-12 Anand Bhaskar Officer A-Award A Stock Option (right to buy) 75,000 17.85 1.34M 75,000 D
2025-01-02 Zanganeh Mahkam Director / Officer / 10% Owner A-Award A Stock Option (right to buy) 10,724 18.35 196.8K 10,724 I
2025-01-02 Xia Yu Director A-Award A Stock Option (right to buy) 5,438 18.35 99.8K 5,438 D
2025-01-02 Ronaghi Mostafa Director A-Award A Stock Option (right to buy) 35,000 18.35 642.3K 35,000 D
2025-01-02 Huber Jeff Director A-Award A Stock Option (right to buy) 35,000 18.35 642.3K 35,000 D
2025-01-02 DUGGAN ROBERT W Director / Officer / 10% Owner A-Award A Stock Option (right to buy) 10,724 18.35 196.8K 10,724 D
2025-01-02 Clark Kenneth A Director A-Award A Stock Option (right to buy) 16,991 18.35 311.8K 16,991 D
2025-01-02 Cesano Alessandra Director A-Award A Stock Option (right to buy) 35,000 18.35 642.3K 35,000 D
2025-01-02 Booth Robert F. Director A-Award A Stock Option (right to buy) 35,000 18.35 642.3K 35,000 D
2024-10-11 Clark Kenneth A Director A-Award A Stock Option (right to buy) 200,000 19.95 3.99M 200,000 D
2024-10-03 Zanganeh Mahkam Director / Officer X-InTheMoney A Common Stock 315,681 1.58 498.8K 10,199,776 I
2024-09-11 Zanganeh Mahkam Director / Officer A-Award A Common Stock 44,052 22.70 1,000.0K 24,967,852
2024-09-11 Soni Manmeet Singh Director / Officer A-Award A Common Stock 44,052 22.70 1,000.0K 3,020,242
2024-09-11 Huber Jeff Director A-Award A Common Stock 44,052 22.70 1,000.0K 44,052
2024-09-11 DUGGAN ROBERT W Director / Officer / 10% Owner A-Award A Common Stock 3,325,991 22.70 75.50M 551,695,096
2024-09-11 Anand Bhaskar Officer A-Award A Common Stock 22,026 22.70 500.0K 131,426
2024-08-23 Zanganeh Mahkam Director / Officer A-Award A Performance Stock Option (right to buy) 2,397,640 1.68 4.03M 2,397,640
2024-08-23 Soni Manmeet Singh Director / Officer A-Award A Performance Stock Option (right to buy) 2,800,000 1.68 4.70M 2,800,000
2024-06-27 Huber Jeff Director A-Award A Stock Option (right to buy) 17,883 7.87 140.7K 217,883
2024-04-11 Ronaghi Mostafa Director A-Award A Stock Option (right to buy) 25,315 4.03 102.0K 225,315
2024-04-02 Soni Manmeet Singh Director / Officer A-Award A Stock Option (right to buy) 1,100,000 3.85 4.24M 1,100,000
2024-04-02 Anand Bhaskar Officer A-Award A Stock Option (right to buy) 600,000 3.85 2.31M 600,000
2024-03-27 Zanganeh Mahkam Director / Officer P-Purchase A Common Stock 20,000 3.71 74.2K 50,000
2024-03-26 Zanganeh Mahkam Director / Officer P-Purchase A Common Stock 30,000 3.75 112.5K 30,000
2024-03-26 Dhingra Ankur Officer P-Purchase A Common Stock 100,000 3.75 375.0K 354,958
2024-01-02 Xia Yu Director A-Award A Stock Option (right to buy) 200,000 2.64 528.0K 235,000
2024-01-02 Mahatme Ujwala Director A-Award A Stock Option (right to buy) 35,000 2.64 92.4K 35,000
2024-01-02 DUGGAN ROBERT W Director / Officer / 10% Owner A-Award A Stock Option (right to buy) 74,545 2.64 196.8K 74,545
2024-01-02 Clark Kenneth A Director A-Award A Stock Option (right to buy) 70,492 2.64 186.1K 105,492
2024-01-02 Cesano Alessandra Director A-Award A Stock Option (right to buy) 35,000 2.64 92.4K 35,000
2024-01-02 Booth Robert F. Director A-Award A Stock Option (right to buy) 35,000 2.64 92.4K 35,000
2023-12-31 Xia Yu Director 0 0.00 0
2023-12-13 Dhingra Ankur Officer P-Purchase A Common Stock 700 2.15 1.5K 235,258
2023-12-12 Zanganeh Mahkam Director / Officer P-Purchase A Common Stock 5,000 2.07 10.4K 494,814
2023-12-11 Zanganeh Mahkam Director / Officer X-InTheMoney D Warrant (right to buy) 489,814 1.44 705.3K 0
2023-10-13 Zanganeh Mahkam Director / Officer A-Award A Stock Option (right to buy) 11,988,198 1.68 20.14M 11,988,198
2023-10-13 Soni Manmeet Singh Director / Officer A-Award A Stock Option (right to buy) 14,000,000 1.68 23.52M 14,000,000
2023-03-08 Zanganeh Mahkam Director / Officer P-Purchase A Common Stock 804,672 1.05 844.9K 1,178,529
2023-03-07 Dhingra Ankur Officer P-Purchase A Common Stock 196,362 1.05 206.2K 234,558
2023-03-06 DUGGAN ROBERT W Director / Officer P-Purchase A Common Stock 376,489,880 1.05 395.31M 552,354,161
2023-01-17 Xia Yu 0
2023-01-03 Soni Manmeet Singh Director A-Award A Stock Option (right to buy) 35,000 0.00 35,000
2023-01-03 Mahatme Ujwala Director A-Award A Stock Option (right to buy) 35,000 0.00 35,000
2023-01-03 Clark Kenneth A Director A-Award A Stock Option (right to buy) 35,000 0.00 35,000
2023-01-03 Cesano Alessandra Director A-Award A Stock Option (right to buy) 35,000 0.00 35,000
2023-01-03 Booth Robert F. Director A-Award A Stock Option (right to buy) 35,000 0.00 35,000
2022-12-06 Zanganeh Mahkam Officer J-Other A Common Stock 373,857 0.00 10,930,849
2022-12-06 DUGGAN ROBERT W Officer J-Other A Common Stock 9,346,434 0.00 171,879,226
2022-11-15 Cesano Alessandra Director A-Award A Stock Option (right to buy) 4,166 0.00 204,166
2022-09-28 Booth Robert F. Director 0 0.00 0
2022-08-16 Zanganeh Maky Officer P-Purchase A Common Stock 1,030,925 0.97 1,000.0K 3,135,466
2022-08-16 Dhingra Ankur Officer P-Purchase A Common Stock 11,557 0.97 11.2K 38,057
2022-08-16 DUGGAN ROBERT W Officer P-Purchase A Common Stock 94,849,203 0.97 92.00M 162,532,792
2022-06-01 Maranian Jeffrey R Officer D Stock Option (right to buy) 20,000 6.61 132.2K 0
2022-05-31 Dhingra Ankur Officer D Common Stock 0 0.00 26,500
2022-05-23 DUGGAN ROBERT W Officer J-Other A Common Stock 21,135 0.00 67,683,589
2022-04-25 Gayko Urte Director A-Award A Stock Option (right to buy) 400,000 0.00 400,000
2022-01-03 Soni Manmeet Singh Director A-Award A Stock Option (right to buy) 82,446 2.82 232.5K 107,446
2022-01-03 Mahatme Ujwala Director A-Award A Stock Option (right to buy) 47,872 2.82 135.0K 72,872
2022-01-03 Gayko Urte Director A-Award A Stock Option (right to buy) 42,553 2.82 120.0K 67,553
2022-01-03 Clark Kenneth A Director A-Award A Stock Option (right to buy) 58,510 2.82 165.0K 83,510
2021-12-15 Zanganeh Maky Director / Officer A-Award A Stock Option (right to buy) 15,000 4.75 71.3K 15,000
2021-12-15 Maranian Jeffrey R Officer A-Award A Stock Option (right to buy) 15,000 4.75 71.3K 15,000
2021-11-22 Maranian Jeffrey R Officer D Stock Option (right to buy) 112,500 4.40 495.0K 0
2021-11-11 Maranian Jeffrey R Officer A-Award A Stock Option (right to buy) 50,000 5.28 264.0K 50,000
2021-11-03 Gayko Urte Director A-Award A Stock Option (right to buy) 4,041 5.54 22.4K 204,041
2021-10-07 Clark Kenneth A Director A-Award A Stock Option (right to buy) 6,250 5.03 31.4K 206,250
2021-05-12 Zanganeh Maky Director / Officer P-Purchase A Common Stock 389,077 5.24 2.04M 2,643,319
2021-05-12 DUGGAN ROBERT W Director / Officer / 10% Owner P-Purchase A Common Stock 11,365,921 5.24 59.56M 67,662,454
2021-02-28 Wang Luhua Director A-Award A Stock Option (right to buy) 21,096 6.77 142.8K 91,096
2021-02-26 Wang Luhua Director A-Award A Stock Option (right to buy) 70,000 6.77 473.9K 70,000
2021-02-19 Soni Manmeet Singh Director A-Award A Stock Option (right to buy) 25,000 7.33 183.3K 252,273
2021-02-19 Mahatme Ujwala Director A-Award A Stock Option (right to buy) 25,000 7.33 183.3K 238,340
2021-02-19 Erdtmann Rainer M Director A-Award A Stock Option (right to buy) 25,000 7.33 183.3K 252,273
2021-02-19 Donaldson Michael Paul Officer D-Return D Stock Option (right to buy) 5,110 3.52 18.0K 594,890
2020-11-30 Powell David Jonathan Officer S-Sale D Common Stock 13,713 4.44 60.9K 0
2020-11-27 Powell David Jonathan Officer M-Exempt A Common Stock 16,616 1.92 31.9K 16,616
2020-11-25 Powell David Jonathan Officer M-Exempt A Common Stock 12,070 1.92 23.2K 12,070
2020-11-24 Powell David Jonathan Officer S-Sale D Common Stock 11,374 4.21 47.9K 0
2020-11-23 Powell David Jonathan Officer S-Sale D Common Stock 6,987 4.40 30.7K 0
2020-11-22 Zanganeh Maky Director / Officer A-Award A Stock Option (right to buy) 2,400,000 4.40 10.56M 3,724,499
2020-11-11 Zanganeh Maky Director I Common Stock 0 0.00 2,254,242
2020-11-06 DUGGAN ROBERT W Director / Officer / 10% Owner P-Purchase A Common Stock 14,071,856 3.34 47.00M 56,296,533
2020-10-04 Graham Camilla Officer A-Award A Stock Option (right to buy) 400,000 3.34 1.34M 400,000
2020-10-02 DUGGAN ROBERT W Director / Officer / 10% Owner A-Award A Common Stock 9,730,539 3.34 32.50M 9,730,539
2020-09-18 Stefanov Ventzislav Director / Officer D Common Stock 0 0.00 14,900
2020-09-18 Soni Manmeet Singh Director D Stock Option (right to buy) 200,000 1.37 274.0K 0
2020-09-18 Powell David Jonathan Officer D Stock Option (right to buy) 84,686 1.92 162.6K 0
2020-09-18 Houbiers Jos Officer D Stock Option (right to buy) 20,000 3.17 63.4K 0
2020-09-18 Erdtmann Rainer M Director D Stock Option (right to buy) 27,273 3.30 90.0K 0
2020-09-18 Donaldson Michael Paul Officer D Stock Option (right to buy) 600,000 3.52 2.11M 0
2020-09-18 DUGGAN ROBERT W Director / Officer / 10% Owner D Common Stock 0 0.00 42,224,677
2020-06-30 Zanganeh Maky Director D Warrant (right to buy) 489,815 1.44 705.3K 0
2020-06-24 Zanganeh Maky Director I Warrant (right to buy) 315,681 1.58 498.8K 0
2020-06-24 DUGGAN ROBERT W Director / Officer / 10% Owner D Warrant (right to buy) 3,985,055 1.58 6.30M 0

Executive team

Top executives
Shares Outstanding
775.37M

Executive compensation

Executive compensation (annual)
# Year Executive Salary Bonus Stock award Option award Incentive Other Total % Stock-
based
Filing
1 2025 Manmeet Soni, Chief Operating Officer, Chief Financial Officer and Director 616.5K 388.4K 248.10M 21.0K 249.13M 99.59%
2 2025 Mahkam Zanganeh, Co-Chief Executive Officer, President and Director 616.5K 388.4K 245.02M 21.0K 246.05M 99.58%
3 2025 Robert W. Duggan, Co-Chief Executive Officer and Chairman 172.4K 172.4K 0.00%
4 2024 Manmeet Soni, Chief Operating Officer, Chief Financial Officer and Director 600.0K 640.0K 3.51M 21.0K 4.77M 73.58%
5 2024 Mahkam Zanganeh, Co-Chief Executive Officer, President and Director 600.0K 540.0K 21.0K 1.16M 0.00%
6 2024 Ankur Dhingra, Former Chief Financial Officer 144.2K 91.3K 20.8K 256.3K 0.00%
7 2024 Robert W. Duggan, Co-Chief Executive Officer and Chairman 158.6K 158.6K 0.00%
8 2023 Manmeet Soni, Chief Operating Officer and Chief Financial Officer 100.0K 23.38M 131.7K 23.61M 99.02%
9 2023 Manmeet Soni, Chief Operating Officer, Chief Financial Officer and Director 100.0K 23.38M 131.7K 23.61M 99.02%
10 2023 Mahkam Zanganeh, Co-Chief Executive Officer, President and Director 600.0K 19.91M 57.8K 20.56M 96.80%
11 2023 Mahkam Zanganeh, Director, Chief Executive Officer, and President 600.0K 19.91M 57.8K 20.56M 96.80%
12 2023 Ankur Dhingra, Former Chief Financial Officer 500.0K 91.3K 30.0K 621.3K 0.00%
13 2022 Ankur Dhingra, Chief Financial Officer 264.2K 381.9K 694.5K 22.2K 1.36M 50.96%
14 2022 Ankur Dhingra, Former Chief Financial Officer 264.2K 381.9K 694.5K 22.2K 1.36M 50.96%
15 2022 Mahkam Zanganeh, Director, co-Chief Executive Officer, and President 450.0K 452.5K 307.2K 32.3K 1.24M 24.73%
16 2022 Mahkam Zanganeh, Co-Chief Executive Officer, President and Director 450.0K 452.5K 307.2K 32.3K 1.24M 24.73%
17 2022 Mahkam Zanganeh, Director, Chief Executive Officer, and President 450.0K 452.5K 307.2K 32.3K 1.24M 24.73%
18 2021 Mahkam Zanganeh, Director and Chief Operations Officer 450.0K 182.3K 8.99M 19.2K 9.64M 93.24%
19 2021 Mahkam Zanganeh, Director, co-Chief Executive Officer, and President 450.0K 182.3K 8.99M 19.2K 9.64M 93.24%
20 2021 Mahkam Zanganeh, Director, Chief Executive Officer, and President 450.0K 182.3K 8.99M 19.2K 9.64M 93.24%
21 2021 David Powell, Former Chief Scientific Officer 288.5K 1.24M 75.8K 1.61M 77.33%
22 2021 Jeffrey Maranian, Principal Accounting Officer 289.6K 707.1K 47.5K 1.04M 67.72%
23 2020 Michael Donaldson, Chief Financial Officer 206.7K 79.9K 665.2K 9.6K 961.4K 69.19%
24 2020 Ventzislav Stefanov, Former Executive Vice President, President of Discuva and Director 290.7K 277.5K 106.6K 674.8K 41.12%
25 2020 Glyn Edwards, Former Chief Executive Officer and Director 137.9K 3.2K 480.7K 621.8K 0.00%
26 2020 Mahkam Zanganeh, Director and Chief Operations Officer 49.6K 476.3K 1.4K 527.3K 90.33%
27 2020 Mahkam Zanganeh, Director, co-Chief Executive Officer, and President 49.6K 476.3K 1.4K 527.3K 90.33%
28 2020 Mahkam Zanganeh, Director and Chief Operating Officer 49.6K 476.3K 1.4K 527.3K 90.33%
29 2020 David Powell, Former Chief Scientific Officer 266.9K 46.8K 87.4K 401.1K 0.00%
30 2019 Glyn Edwards, Former Chief Executive Officer and Director 378.1K 2.6K 459.3K 31.9K 871.9K 52.68%
CEO compensation breakdown

Proxy statements

Proxy statements (DEF 14A)
Filing date Form type Filing
2026-04-17 DEFA14A
2026-04-17 DEF 14A
2026-04-06 PRE 14A
2025-04-29 DEF 14A
2024-06-13 DEFA14A

Recent SEC filings

Recent SEC filings
Filing date Form type Filing
2026-04-30 8-K
2026-04-30 10-Q
2026-04-17 DEFA14A
2026-04-17 DEF 14A
2026-04-17 ARS
2026-04-06 PRE 14A
2026-02-23 S-8
2026-02-23 8-K
2026-02-23 10-K
2026-01-29 8-K

Executive team

NameTitleCompensationGender
Mahkam Zanganeh Co-CEO, President & Director 1M
Manmeet Singh Soni Chief Operating Officer, Chief Financial Officer & Director 1M male
Robert W. Duggan Co-CEO & Executive Chairman 172.4K male
Fong Clow Chief Biometrics Officer
Kay Elizabeth Davies Co-Founder, Chairman of Scientific Advisory Board and Scientific Advisor
Laura Q. Chow Senior Vice President of Clinical Development
Nathan LiaBraaten Senior Director of Investor Relations male
Robert LaCaze Chief Commercial Officer male
Urte Gayko Chief Regulatory, Quality & Pharmacovigilance Officer
Allen S. Yang Head of R&D Strategy
Wang Clow Fong Chief Biometrics Officer
Bhaskar Anand Chief Accounting Officer male
ESG Rating
B
BIOTECHNOLOGY
2026
E (Environmental)
63.2 / 56.3
Company / Sector avg.
S (Social)
71.1 / 62.4
Company / Sector avg.
G (Governance)
68.5 / 60.9
Company / Sector avg.
ESG Total
67.6 / 59.9
Company / Sector avg.
ESG Score History BIOTECHNOLOGY
Benchmark vs Sector
Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend history

Earnings history

Earnings reports

Stock splits