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Sagimet Biosciences Inc. (SGMT)

USD7.68 -0.07 (-0.92%)
US NASDAQ Healthcare Biotechnology
Address 155 Bovet Road 94402
San Mateo, CA, US
CEO David Happel
IPO 2023-07-14
CIK 1400118 ISIN US7867001049

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Description

Sagimet Biosciences Inc., a clinical-stage biopharmaceutical company, develops novel therapeutics called fatty acid synthase (FASN) inhibitors for the treatment of diseases that result from dysfunctional metabolic and fibrotic pathways in the United States. The company’s lead drug candidate is Denifanstat, an oral, once-daily pill and selective FASN inhibitor for the treatment of metabolic dysfunction-associated steatohepatitis, acne, and select forms of cancer. It also develops TVB-3567, a FASN inhibitor for the treatment of acne indication; and other oncology programs, such as solid tumor and glioblastoma. The company was formerly known as 3-V Biosciences, Inc. and changed its name to Sagimet Biosciences Inc. in August 2019. Sagimet Biosciences Inc. was incorporated in 2006 and is headquartered in San Mateo, California.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
USD7.68 -0.07 (-0.92%)
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Volume Profile
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Liquidity & share structure
Average Volume
2M
Beta
3.44
Float Shares
31.21M
Free Float %
95.8%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
+0.28% +1.67% -9.22% +27.67% +0.97% +23.14% +108.88% -54.29% -54.29% -54.29% -54.29%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
vs.
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Analyst Consensus (7 ratings, all time) Buy
Price Targets & DCF
Current price
7.68
Low 8.00 +4.1%
Consensus 8.00 +4.1%
Median 8.00 +4.1%
High 8.00 +4.1%
DCF (Unlevered) 1.05 -86.4%
DCF (Levered) 1.08 -85.9%

DCF figures are point estimates: small changes in growth or discount-rate assumptions move them materially. Read them as a reference, not a precise target.

Ratings Trend (MoM) 90% Bullish
Rating 2026-05 Change
Strong Buy 1 0
Buy 8 0
Hold 1 0
Sell 0 0
Strong Sell 0 0
Price Target Summary
Period # Analysts Avg Target
Last Month
Last Quarter
Last Year 1
8.00
+4.1%
All Time 2
7.00
-8.9%
Quality scores
Altman Z-Score
21.91
Safe zone
Piotroski F-Score
1 / 9
Weak
MOAT Score
2 / 10
No MOAT
Composite Rating
C+
Overall Score
2 / 5
Medium
DCF Score
3 / 5
Medium
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
4 / 5
High
P/E Score
1 / 5
Low
P/Book Score
3 / 5
Medium
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
  • EPS growth Biotechnology: +29.7%
    -9.0% Q1'26: +41.1% (vs Q1'25)
  • FCF margin FCF growth · Biotechnology: +16.2%
  • EBIT margin Biotechnology: +0.0%
  • ROIC Biotechnology: -16.1%
    Q1'26: +2,294.4% (vs Q1'25)
  • Share dilution Biotechnology: -3.4%
    +3.2% Q1'26: +1.1% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    0.00× Q1'26: 0.00× (vs Q1'25)
Valuation Multiples From To
DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (3.63) × ERP
WACC = 100% × Ke + 0% × Kd (4.1%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Intrinsic value (base): 1.05 Current price: 7.68
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2023
actual
Dec 2024
actual
Dec 2025
actual
Dec 2026
6 Rev. Ana.
7 EPS Ana.
Dec 2027
6 Rev. Ana.
7 EPS Ana.
Dec 2028
8 Rev. Ana.
8 EPS Ana.
Dec 2029
7 Rev. Ana.
6 EPS Ana.
Dec 2030
7 Rev. Ana.
6 EPS Ana.
Revenue
2.00M
est: 2.00M (+0.0%)
est: 1.00M (-100.0%)
111.1K
111.1K – 111.1K
-88.9% YoY
7.53M
7.53M – 7.53M
+6,673.9% YoY
23.87M
23.87M – 23.87M
+217.1% YoY
91.45M
91.45M – 91.45M
+283.1% YoY
252.46M
252.46M – 252.46M
+176.1% YoY
EBITDA
-30.74M
est: 1.20M (-2,661.7%)
-45.57M
-56.89M
est: 600.0K (-9,581.5%)
66.7K
66.7K – 66.7K
-88.9% YoY
4.52M
4.52M – 4.52M
+6,673.9% YoY
14.32M
14.32M – 14.32M
+217.1% YoY
54.87M
54.87M – 54.87M
+283.1% YoY
151.48M
151.48M – 151.48M
+176.1% YoY
EBIT
-30.74M
est: 1.20M (-2,661.7%)
-45.57M
-56.89M
est: 600.0K (-9,581.5%)
66.7K
66.7K – 66.7K
-88.9% YoY
4.52M
4.52M – 4.52M
+6,673.9% YoY
14.32M
14.32M – 14.32M
+217.1% YoY
54.87M
54.87M – 54.87M
+283.1% YoY
151.48M
151.48M – 151.48M
+176.1% YoY
Net Income
-27.88M
est: -51.09M (+45.4%)
-45.57M
est: -50.67M (+10.1%)
-51.04M
est: -53.67M (+4.9%)
-39.99M
-49.94M – -30.03M
+25.5% YoY
-39.25M
-53.67M – -24.83M
+1.8% YoY
-63.61M
-98.15M – -29.07M
-62.1% YoY
-31.81M
-31.81M – -31.81M
+50.0% YoY
11.86M
11.86M – 11.86M
+137.3% YoY
SGA
12.96M
est: 4.19M (+209.2%)
16.01M
17.84M
est: 2.10M (+750.8%)
232.9K
232.9K – 232.9K
-88.9% YoY
15.78M
15.78M – 15.78M
+6,673.9% YoY
50.04M
50.04M – 50.04M
+217.1% YoY
191.70M
191.70M – 191.70M
+283.1% YoY
529.23M
529.23M – 529.23M
+176.1% YoY
EPS
-1.53
est: -1.58 (+3.1%)
-1.45
est: -1.57 (+7.5%)
-1.58
est: -1.66 (+5.1%)
-1.20
-1.54 – -0.93
+27.9% YoY
-1.25
-1.66 – -0.77
-4.2% YoY
-1.63
-3.03 – -0.90
-30.1% YoY
-0.98
-0.98 – -0.98
+39.5% YoY
0.37
0.37 – 0.37
+137.3% YoY
Recent Grade Changes (3M)
Date Firm Previous New Grade Action
2026-05-19 Citizens Market Outperform Market Outperform Maintain
2026-05-04 Canaccord Genuity Buy Buy Maintain
2026-04-29 Guggenheim Buy Buy Maintain
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-28 C+ 2/5 3/5 1/5 1/5 4/5 1/5 3/5
2026-05-27 C+ 2/5 3/5 1/5 1/5 4/5 1/5 3/5
2026-05-26 C+ 2/5 3/5 1/5 1/5 4/5 1/5 3/5
2026-05-22 C+ 2/5 3/5 1/5 1/5 4/5 1/5 3/5
2026-05-21 C+ 2/5 3/5 1/5 1/5 4/5 1/5 3/5
2026-05-20 C+ 2/5 3/5 1/5 1/5 4/5 1/5 3/5
2026-05-19 C+ 2/5 3/5 1/5 1/5 4/5 1/5 3/5
2026-05-18 C+ 2/5 3/5 1/5 1/5 4/5 1/5 3/5
2026-05-15 C+ 2/5 3/5 1/5 1/5 4/5 1/5 3/5
2026-05-14 C+ 2/5 3/5 1/5 1/5 4/5 1/5 3/5
2026-05-13 B- 2/5 3/5 1/5 1/5 4/5 1/5 4/5
2026-05-12 B- 2/5 3/5 1/5 1/5 4/5 1/5 4/5
2026-05-11 C+ 2/5 3/5 1/5 1/5 4/5 1/5 3/5
2026-05-08 B- 2/5 3/5 1/5 1/5 4/5 1/5 4/5
2026-05-07 B- 2/5 3/5 1/5 1/5 4/5 1/5 4/5
2026-05-06 B- 2/5 3/5 1/5 1/5 4/5 1/5 4/5
2026-05-05 B- 2/5 3/5 1/5 1/5 4/5 1/5 4/5
2026-05-04 B- 2/5 3/5 1/5 1/5 4/5 1/5 4/5
2026-05-01 C+ 2/5 3/5 1/5 1/5 3/5 1/5 4/5
2026-04-30 C+ 2/5 3/5 1/5 1/5 3/5 1/5 4/5
2026-04-29 C+ 2/5 3/5 1/5 1/5 3/5 1/5 3/5
2026-04-28 C+ 2/5 3/5 1/5 1/5 3/5 1/5 3/5
2026-04-27 C+ 2/5 3/5 1/5 1/5 3/5 1/5 3/5
2026-04-24 C+ 2/5 3/5 1/5 1/5 3/5 1/5 3/5
2026-04-23 C+ 2/5 3/5 1/5 1/5 3/5 1/5 3/5
2026-04-22 C+ 2/5 3/5 1/5 1/5 3/5 1/5 3/5
2026-04-21 C 2/5 3/5 1/5 1/5 2/5 1/5 3/5
2026-04-20 C 2/5 3/5 1/5 1/5 2/5 1/5 3/5
2026-04-17 C 2/5 3/5 1/5 1/5 2/5 1/5 3/5
2026-04-16 C 2/5 3/5 1/5 1/5 2/5 1/5 3/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
-39.72M
OE per share TTM
-1.23
Owner's Yield
-16.74%
Maintenance CapEx ratio
Maint CapEx / Avg PPE
64.7%

Ownership Overview

Ownership breakdown
At a glance
Institutional holders
92
Total invested
69.76M
Insider transactions (90d)
1
Beneficial owners (>5%)
1
Beneficial owners (>5%)
# Reporting person Amount owned % of class Sole voting Shared voting Sole dispositive Shared dispositive Type Citizenship Filing date SEC filing
1 Blue Owl Capital Holdings LP 1.67M 5.46% 1.67M 1.67M PN Delaware 2024-11-14

Institutional Activity (13F)

Institutional ownership trend From To
13F snapshot — 2026 Q1
Investors holding
92
-2 vs prev Q
New positions
17
Closed positions
17
Increased
50
Reduced
17
Put/Call ratio
0.65
Calls held
252.0K
Puts held
163.1K
Top institutional holders
# Investor Shares / Δ Mkt value / Δ Own% / Δ Weight% / Δ Avg px / Perf. Hold / Status
1 DUMAC, INC. 71.2K +71.2K (+100.0%) 421.46M +421.5M (+100.0%) 0.22% +0.219 pp 0.06% +0.065 pp USD5.92 +0.0% 1 qtrs NEW
2 VANGUARD GROUP INC 1.26M +56.3K (+4.7%) 7.46M -797.6K (-9.7%) 3.88% +0.142 pp 0.00% +0.000 pp USD5.88 +0.7% 10 qtrs
3 BLUE OWL CAPITAL HOLDINGS LP 1.24M -84.5K (-6.4%) 7.36M -1.7M (-19.2%) 3.83% -0.295 pp 0.55% -2.278 pp USD5.26 +12.5% 9 qtrs
4 AFFINITY ASSET ADVISORS, LLC 1.15M +798.2K (+228.1%) 6.80M +4.4M (+183.1%) 3.54% +2.450 pp 0.39% +0.178 pp USD6.21 -4.7% 2 qtrs
5 WOODLINE PARTNERS LP 1.00M -500.4K (-33.3%) 5.93M -4.4M (-42.5%) 3.08% -1.580 pp 0.02% -0.026 pp USD7.62 -22.3% 3 qtrs
6 BAKER BROS. ADVISORS LP 953.0K +— (+0.0%) 5.64M -895.8K (-13.7%) 2.94% -0.025 pp 0.03% -0.014 pp USD7.31 -19.0% 10 qtrs
7 BLACKROCK, INC. 814.0K +201.2K (+32.8%) 4.82M +615.4K (+14.6%) 2.51% +0.604 pp 0.00% +0.000 pp USD4.23 +40.0% 6 qtrs
8 MARSHALL WACE, LLP 780.4K +780.4K (+100.0%) 4.62M +4.6M (+100.0%) 2.40% +2.404 pp 0.00% +0.004 pp USD5.92 +0.0% 1 qtrs NEW
9 HHLR ADVISORS, LTD. 724.8K +— (+0.0%) 4.29M -681.3K (-13.7%) 2.23% -0.019 pp 0.14% +0.017 pp USD8.80 -32.7% 10 qtrs
10 SIREN, L.L.C. 724.8K +— (+0.0%) 4.29M -681.3K (-13.7%) 2.23% -0.019 pp 0.13% -0.067 pp USD2.77 +113.7% 6 qtrs
11 MILLENNIUM MANAGEMENT LLC 586.9K -189.4K (-24.4%) 3.47M -1.9M (-34.8%) 1.81% -0.604 pp 0.00% -0.001 pp USD6.65 -11.0% 10 qtrs
12 D. E. SHAW & CO., INC. 485.5K -215.7K (-30.8%) 2.87M -1.9M (-40.3%) 1.50% -0.683 pp 0.00% -0.001 pp USD7.02 -15.7% 3 qtrs
13 RENAISSANCE TECHNOLOGIES LLC 342.5K +181.1K (+112.2%) 2.03M +920.4K (+83.1%) 1.06% +0.554 pp 0.00% +0.002 pp USD6.43 -7.9% 9 qtrs
14 HUDSON BAY CAPITAL MANAGEMENT LP 304.5K +304.5K (+100.0%) 1.80M +1.8M (+100.0%) 0.94% +0.938 pp 0.01% +0.006 pp USD5.92 +0.0% 1 qtrs NEW
15 BRIDGEWAY CAPITAL MANAGEMENT, LLC 299.6K +— (+0.0%) 1.77M -281.7K (-13.7%) 0.92% -0.008 pp 0.04% -0.007 pp USD6.52 -9.2% 9 qtrs
16 GEODE CAPITAL MANAGEMENT, LLC 295.9K +12.6K (+4.5%) 1.75M -191.5K (-9.9%) 0.91% +0.032 pp 0.00% +0.000 pp USD5.09 +16.3% 10 qtrs
17 RAYMOND JAMES FINANCIAL INC 286.3K +8.0K (+2.9%) 1.69M -214.2K (-11.2%) 0.88% +0.018 pp 0.00% 0.000 pp USD3.51 +68.7% 4 qtrs
18 PALE FIRE CAPITAL SE 221.9K +221.9K (+100.0%) 1.31M +1.3M (+100.0%) 0.68% +0.683 pp 0.09% +0.088 pp USD5.92 +0.0% 1 qtrs NEW
19 UBS GROUP AG 201.8K -105.0K (-34.2%) 1.19M -910.0K (-43.2%) 0.62% -0.331 pp 0.00% 0.000 pp USD4.59 +29.0% 10 qtrs
20 POINT72 ASSET MANAGEMENT, L.P. 175.8K +175.8K (+100.0%) 1.04M +1.0M (+100.0%) 0.54% +0.542 pp 0.00% +0.001 pp USD5.92 +0.0% 1 qtrs NEW
21 VERITION FUND MANAGEMENT LLC 154.7K +154.7K (+100.0%) 915.6K +915.6K (+100.0%) 0.48% +0.476 pp 0.00% +0.004 pp USD5.92 +0.0% 1 qtrs NEW
22 FNY INVESTMENT ADVISERS, LLC 142.9K +32.2K (+29.1%) 845.0K +86.0K (+11.3%) 0.44% +0.096 pp 0.24% -0.006 pp USD4.61 +28.4% 8 qtrs
23 DIMENSIONAL FUND ADVISORS LP 136.0K +110.7K (+437.0%) 805.3K +631.5K (+363.3%) 0.42% +0.340 pp 0.00% +0.000 pp USD5.66 +4.6% 5 qtrs
24 683 CAPITAL MANAGEMENT, LLC 126.3K +126.3K (+100.0%) 748.0K +748.0K (+100.0%) 0.39% +0.389 pp 0.03% +0.033 pp USD5.92 +0.0% 1 qtrs NEW
25 GOLDMAN SACHS GROUP INC 125.9K +110.8K (+729.0%) 745.6K +641.4K (+615.4%) 0.39% +0.341 pp 0.00% +0.000 pp USD5.62 +5.3% 10 qtrs
26 STATE STREET CORP 117.4K +6.9K (+6.2%) 694.9K -63.0K (-8.3%) 0.36% +0.018 pp 0.00% +0.000 pp USD5.16 +14.7% 10 qtrs
27 QUBE RESEARCH & TECHNOLOGIES LTD 111.3K +4.5K (+4.2%) 659.2K -73.8K (-10.1%) 0.34% +0.011 pp 0.00% 0.000 pp USD6.82 -13.2% 5 qtrs
28 RB CAPITAL MANAGEMENT, LLC 97.0K +97.0K (+100.0%) 574.2K +574.2K (+100.0%) 0.30% +0.299 pp 0.11% +0.114 pp USD5.92 +0.0% 1 qtrs NEW
29 CITADEL ADVISORS LLC 92.6K +47.4K (+104.9%) 548.2K +238.1K (+76.8%) 0.29% +0.145 pp 0.00% +0.000 pp USD6.02 -1.7% 7 qtrs
30 JANE STREET GROUP, LLC 92.4K +79.6K (+619.9%) 547.2K +459.1K (+521.2%) 0.28% +0.245 pp 0.00% +0.000 pp USD5.72 +3.5% 8 qtrs
31 XTX TOPCO LTD 91.7K +32.0K (+53.6%) 543.1K +133.3K (+32.5%) 0.28% +0.097 pp 0.01% -0.007 pp USD6.23 -5.0% 4 qtrs
32 MORGAN STANLEY 89.2K -156.8K (-63.7%) 528.3K -1.2M (-68.7%) 0.27% -0.489 pp 0.00% 0.000 pp USD4.43 +33.6% 10 qtrs
33 SQUAREPOINT OPS LLC 84.7K +49.7K (+141.6%) 501.6K +261.1K (+108.5%) 0.26% +0.152 pp 0.00% +0.000 pp USD6.31 -6.2% 2 qtrs
34 BNP PARIBAS ARBITRAGE, SNC 75.1K +74.8K (+20,943.7%) 444.7K +442.3K (+18,060.3%) 0.23% +0.230 pp 0.00% +0.000 pp USD5.93 -0.2% 5 qtrs
35 KESTRA ADVISORY SERVICES, LLC 66.0K +66.0K (+100.0%) 390.8K +390.8K (+100.0%) 0.20% +0.203 pp 0.00% +0.002 pp USD5.92 +0.0% 1 qtrs NEW
36 AMERICAN CENTURY COMPANIES INC 61.4K +2.9K (+5.0%) 363.4K -37.6K (-9.4%) 0.19% +0.008 pp 0.00% +0.000 pp USD4.99 +18.6% 5 qtrs
37 SUSQUEHANNA INTERNATIONAL GROUP, LLP 56.5K -105.4K (-65.1%) 334.5K -776.2K (-69.9%) 0.17% -0.329 pp 0.00% 0.000 pp USD6.24 -5.1% 5 qtrs
38 NORTHERN TRUST CORP 55.5K +3.2K (+6.1%) 328.6K -30.1K (-8.4%) 0.17% +0.009 pp 0.00% +0.000 pp USD5.52 +7.2% 10 qtrs
39 OMERS ADMINISTRATION CORP 53.4K +53.4K (+100.0%) 316.1K +316.1K (+100.0%) 0.16% +0.165 pp 0.00% +0.002 pp USD5.92 +0.0% 1 qtrs NEW
40 TWO SIGMA INVESTMENTS, LP 42.5K -8.7K (-16.9%) 251.8K -99.4K (-28.3%) 0.13% -0.028 pp 0.00% 0.000 pp USD6.08 -2.6% 9 qtrs
41 HIGHTOWER ADVISORS, LLC 37.2K +3.4K (+10.1%) 220.2K -11.6K (-5.0%) 0.11% +0.010 pp 0.00% +0.000 pp USD7.42 -20.2% 3 qtrs
42 MAN GROUP PLC 35.6K -11.3K (-24.2%) 210.8K -111.3K (-34.5%) 0.11% -0.036 pp 0.00% 0.000 pp USD6.86 -13.7% 2 qtrs
43 MARINER, LLC 32.1K +7.0K (+27.9%) 190.0K +17.8K (+10.4%) 0.10% +0.021 pp 0.00% +0.000 pp USD4.98 +18.9% 4 qtrs
44 ABACUS PLANNING GROUP, INC. 30.0K +— (+0.0%) 177.4K -28.2K (-13.7%) 0.09% -0.001 pp 0.02% -0.005 pp USD3.82 +55.0% 4 qtrs
45 BARCLAYS PLC 29.3K -27.9K (-48.7%) 173.7K +15.2K (+9.6%) 0.09% -0.087 pp 0.00% +0.000 pp USD6.86 -13.7% 9 qtrs
46 LANDSCAPE CAPITAL MANAGEMENT, L.L.C. 25.9K +3.2K (+14.1%) 153.3K -2.4K (-1.5%) 0.08% +0.009 pp 0.01% +0.000 pp USD6.74 -12.2% 2 qtrs
47 GSA CAPITAL PARTNERS LLP 25.2K -60.1K (-70.4%) 149.0K -436.0K (-74.5%) 0.08% -0.187 pp 0.01% -0.036 pp USD6.86 -13.7% 5 qtrs
48 LIGHTHOUSE INVESTMENT PARTNERS, LLC 22.7K +22.7K (+100.0%) 134.6K +134.6K (+100.0%) 0.07% +0.070 pp 0.00% +0.004 pp USD5.92 +0.0% 1 qtrs NEW
49 DEKABANK DEUTSCHE GIROZENTRALE 20.0K +— (+0.0%) 125.0K -11.0K (-8.1%) 0.06% -0.001 pp 0.00% +0.000 pp USD5.23 +13.2% 8 qtrs
50 LPL FINANCIAL LLC 20.6K +4.9K (+31.3%) 121.8K +14.3K (+13.3%) 0.06% +0.015 pp 0.00% +0.000 pp USD6.64 -10.8% 2 qtrs
51 CRESSET ASSET MANAGEMENT, LLC 20.1K +20.1K (+100.0%) 118.9K +118.9K (+100.0%) 0.06% +0.062 pp 0.00% +0.001 pp USD5.92 +0.0% 1 qtrs NEW
52 CITIGROUP INC 18.0K +18.0K (+100.0%) 106.4K +106.4K (+100.0%) 0.06% +0.055 pp 0.00% +0.000 pp USD5.92 +0.0% 9 qtrs
53 1492 CAPITAL MANAGEMENT LLC 15.0K +— (+0.0%) 88.8K -14.1K (-13.7%) 0.05% 0.000 pp 0.03% -0.008 pp USD6.86 -13.7% 2 qtrs
54 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 15.0K +— (+0.0%) 88.8K -14.1K (-13.7%) 0.05% 0.000 pp 0.00% +0.000 pp USD3.26 +81.6% 4 qtrs
55 SIMPLEX TRADING, LLC 14.2K +14.2K (+100.0%) 84.2K +84.2K (+100.0%) 0.04% +0.044 pp 0.00% +0.000 pp USD5.92 +0.0% 7 qtrs
56 JEFFERIES FINANCIAL GROUP INC. 13.2K -695.0 (-5.0%) 78.2K -17.2K (-18.0%) 0.04% -0.003 pp 0.00% 0.000 pp USD6.86 -13.7% 2 qtrs
57 JASPER RIDGE PARTNERS, L.P. 12.9K -6.1K (-32.3%) 76.2K -54.2K (-41.6%) 0.04% -0.019 pp 0.00% -0.001 pp USD3.26 +81.6% 4 qtrs
58 HAMILTON LANE ADVISORS LLC 11.1K +11.1K (+100.0%) 65.7K +65.7K (+100.0%) 0.03% +0.034 pp 0.04% +0.036 pp USD5.92 +0.0% 1 qtrs NEW
59 VIRTU FINANCIAL LLC 10.4K +10.4K (+100.0%) 62.0K +62.0K (+100.0%) 0.03% +0.032 pp 0.00% +0.002 pp USD5.92 +0.0% 9 qtrs
60 SHERBROOKE PARK ADVISERS LLC 10.1K +10.1K (+100.0%) 60.0K +60.0K (+100.0%) 0.03% +0.031 pp 0.15% +0.155 pp USD5.92 +0.0% 1 qtrs NEW
61 VANGUARD PERSONALIZED INDEXING MANAGEMENT, LLC 10.1K +10.1K (+100.0%) 59.7K +59.7K (+100.0%) 0.03% +0.031 pp 0.00% +0.001 pp USD5.92 +0.0% 1 qtrs NEW
62 WEDMONT PRIVATE CAPITAL 10.8K +10.8K (+100.0%) 59.6K +59.6K (+100.0%) 0.03% +0.033 pp 0.00% +0.002 pp USD5.92 +0.0% 1 qtrs NEW
63 BANK OF AMERICA CORP /DE/ 9.9K -15.8K (-61.6%) 58.5K -117.9K (-66.8%) 0.03% -0.049 pp 0.00% +0.000 pp USD6.43 -7.9% 10 qtrs
64 ROCKEFELLER CAPITAL MANAGEMENT L.P. 9.0K +— (+0.0%) 53.3K -8.5K (-13.7%) 0.03% 0.000 pp 0.00% +0.000 pp USD6.86 -13.7% 2 qtrs
65 WELLS FARGO & COMPANY/MN 8.0K +1.0K (+14.3%) 47.4K -660.0 (-1.4%) 0.02% +0.003 pp 0.00% +0.000 pp USD4.21 +40.6% 5 qtrs
66 ACADIAN ASSET MANAGEMENT LLC 8.0K +8.0K (+100.0%) 46.0K +46.0K (+100.0%) 0.02% +0.025 pp 0.00% +0.000 pp USD5.92 +0.0% 1 qtrs NEW
67 QUEST PARTNERS LLC 6.2K -111.1K (-94.7%) 36.6K -767.8K (-95.5%) 0.02% -0.345 pp 0.00% -0.051 pp USD6.86 -13.7% 2 qtrs
68 CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD. 5.1K +5.1K (+100.0%) 29.9K +29.9K (+100.0%) 0.02% +0.016 pp 0.00% +0.002 pp USD5.92 +0.0% 1 qtrs NEW
69 ROYAL BANK OF CANADA 4.9K +4.4K (+819.2%) 29.0K +26.0K (+866.7%) 0.02% +0.014 pp 0.00% +0.000 pp USD5.84 +1.4% 4 qtrs
70 ANTIPODES PARTNERS LTD 3.2K +— (+0.0%) 18.8K -3.0K (-13.7%) 0.01% 0.000 pp 0.00% 0.000 pp USD7.62 -22.3% 3 qtrs
71 GLOBAL RETIREMENT PARTNERS, LLC 3.0K +— (+0.0%) 17.8K -2.8K (-13.7%) 0.01% 0.000 pp 0.00% 0.000 pp USD7.62 -22.3% 3 qtrs
72 JPMORGAN CHASE & CO 2.5K +2.4K (+2,438.8%) 14.7K +14.1K (+2,091.8%) 0.01% +0.007 pp 0.00% +0.000 pp USD5.85 +1.2% 10 qtrs
73 MIRAE ASSET GLOBAL INVESTMENTS CO., LTD. 1.5K +1.5K (+100.0%) 8.9K +8.9K (+100.0%) 0.00% +0.005 pp 0.00% +0.000 pp USD5.92 +0.0% 1 qtrs NEW
74 VSM WEALTH ADVISORY, LLC 1.5K +1.5K (+100.0%) 8.9K +8.9K (+100.0%) 0.00% +0.005 pp 0.00% +0.003 pp USD5.92 +0.0% 1 qtrs NEW
75 NEWBRIDGE FINANCIAL SERVICES GROUP, INC. 1.5K +— (+0.0%) 8.9K -1.4K (-13.7%) 0.00% +0.000 pp 0.00% 0.000 pp USD4.50 +31.6% 9 qtrs
76 PARALLEL ADVISORS, LLC 849.00 +849.0 (+100.0%) 5.0K +5.0K (+100.0%) 0.00% +0.003 pp 0.00% +0.000 pp USD5.92 +0.0% 1 qtrs NEW
77 CAITONG INTERNATIONAL ASSET MANAGEMENT CO., LTD 823.00 +823.0 (+100.0%) 4.9K +4.9K (+100.0%) 0.00% +0.003 pp 0.00% +0.001 pp USD5.92 +0.0% 1 qtrs NEW
78 TOTH FINANCIAL ADVISORY CORP 650.00 +— (+0.0%) 3.8K -611.0 (-13.7%) 0.00% +0.000 pp 0.00% 0.000 pp USD7.62 -22.3% 3 qtrs
79 GF FUND MANAGEMENT CO. LTD. 608.00 +608.0 (+100.0%) 3.6K +3.6K (+100.0%) 0.00% +0.002 pp 0.00% +0.000 pp USD5.92 +0.0% 1 qtrs NEW
80 MAI CAPITAL MANAGEMENT 500.00 +— (+0.0%) 3.0K -470.0 (-13.7%) 0.00% +0.000 pp 0.00% +0.000 pp USD2.81 +110.7% 6 qtrs
81 SMARTLEAF ASSET MANAGEMENT LLC 500.00 +500.0 (+100.0%) 2.9K +2.9K (+100.0%) 0.00% +0.002 pp 0.00% +0.000 pp USD5.92 +0.0% 1 qtrs NEW
82 RIALTO WEALTH MANAGEMENT, LLC 359.00 +— (+0.0%) 2.1K -337.0 (-13.7%) 0.00% +0.000 pp 0.00% 0.000 pp USD7.62 -22.3% 3 qtrs
83 PHYSICIAN WEALTH ADVISORS, INC. 317.00 +— (+0.0%) 1.9K -298.0 (-13.7%) 0.00% +0.000 pp 0.00% +0.000 pp USD7.62 -22.3% 3 qtrs
84 FEDERATED HERMES, INC. 262.00 -301.0 (-53.5%) 1.6K -2.3K (-59.8%) 0.00% -0.001 pp 0.00% +0.000 pp USD6.86 -13.7% 2 qtrs
85 FMR LLC 133.00 -46.0 (-25.7%) 788.00 -442.0 (-35.9%) 0.00% 0.000 pp 0.00% +0.000 pp USD7.41 -20.1% 10 qtrs
86 SRS CAPITAL ADVISORS, INC. 115.00 +— (+0.0%) 681.00 -108.0 (-13.7%) 0.00% +0.000 pp 0.00% +0.000 pp USD6.85 -13.6% 2 qtrs
87 SBI SECURITIES CO., LTD. 24.00 -12.0 (-33.3%) 142.00 -105.0 (-42.5%) 0.00% +0.000 pp 0.00% +0.000 pp USD5.92 +0.0% 5 qtrs
88 ORG WEALTH PARTNERS, LLC -17.8K (-100.0%) -122.0K (-100.0%) 0.00% -0.055 pp 0.00% -0.026 pp USD 6 qtrs SOLD
89 READYSTATE ASSET MANAGEMENT LP -325.4K (-100.0%) -2.2M (-100.0%) 0.00% -1.011 pp 0.00% -0.095 pp USD 3 qtrs SOLD
90 US BANCORP \DE\ -1.0K (-100.0%) -6.9K (-100.0%) 0.00% -0.003 pp 0.00% +0.000 pp USD 2 qtrs SOLD
91 RISE ADVISORS, LLC -306.0 (-100.0%) -2.1K (-100.0%) 0.00% -0.001 pp 0.00% -0.001 pp USD 3 qtrs SOLD
92 GRAHAM CAPITAL MANAGEMENT, L.P. -49.1K (-100.0%) -336.5K (-100.0%) 0.00% -0.152 pp 0.00% -0.005 pp USD 2 qtrs SOLD
93 SCHONFELD STRATEGIC ADVISORS LLC -523.8K (-100.0%) -3.6M (-100.0%) 0.00% -1.627 pp 0.00% -0.020 pp USD 8 qtrs SOLD
Ownership breakdown by holder

ETF Ownership

Top ETFs holding this stock Held by 54 ETFs in our universe
# ETF Weight Est. AUM exposure TER
1 iShares Health Innovation Active ETF BMED 0.11% 12.4K 0.77%
2 iShares Micro-Cap ETF IWC 0.10% 1.46M 0.60%
3 State Street SPDR S&P Biotech ETF XBI 0.07% 7.27M 0.35%
4 Global X - S&P Biotech ETF CURE.AX 0.07% 23.4K 0.45%
5 iShares Biotechnology ETF IBB 0.03% 3.10M 0.44%
6 Invesco NASDAQ Biotech UCITS ETF SBIO.L 0.03% 143.3K 0.40%
7 Invesco Nasdaq Biotechnology ETF IBBQ 0.03% 23.2K 0.19%
8 iShares Nasdaq US Biotechnology UCITS ETF BTEE.L 0.03% 22.7K 0.35%
9 iShares Nasdaq US Biotechnology UCITS ETF BTEC.L 0.03% 339.6K 0.35%
10 iShares Russell 2000 Growth ETF IWO 0.02% 3.19M 0.24%

Insider Activity

Insider Activity — Latest Quarter
Ratio by transactions
2.00
Bullish
Ratio by volume
3.00
Bullish
Buys
8
Sells
4
Shares acquired
780.0K
Shares disposed
19.7K
Cash buys
Cash sales
4.00
Net activity
+760,325
Insider buys vs sells (history) From To
Recent insider transactions From To
Date Person Role Transaction A/D Security Shares Price Value Owned after D/I Filing
2026-04-20 Grauer Andreas Officer A-Award A Stock Option (Right to Buy) 264,759 6.44 1.71M 264,759 D
2026-02-19 Rozek Elizabeth Officer A-Award A Series A Common Stock 44,000 0.00 234,959 D
2026-02-19 Martins Eduardo Bruno Officer A-Award A Series A Common Stock 44,000 0.00 147,296 D
2026-02-19 Happel David Director / Officer A-Award A Series A Common Stock 128,000 0.00 805,621 D
2026-02-19 Chauche Thierry Officer A-Award A Stock Option (Right to Buy) 88,000 5.38 473.4K 88,000 D
2026-02-10 Rozek Elizabeth Officer S-Sale D Series A Common Stock 2,622 5.36 14.1K 190,959 D
2026-02-10 Martins Eduardo Bruno Officer S-Sale D Series A Common Stock 3,640 5.36 19.5K 103,296 D
2026-02-10 Happel David Director / Officer S-Sale D Series A Common Stock 12,101 5.36 64.9K 677,621 D
2026-02-10 Chauche Thierry Officer S-Sale D Series A Common Stock 1,312 5.36 7.0K 15,688 D
2025-11-20 Kemble George Director / Officer S-Sale D Series A Common Stock 37,688 7.69 290.0K 81,005 D
2025-11-04 Rozek Elizabeth Officer A-Award A Series A Common Stock 9,855 0.00 193,581 D
2025-07-21 Rozek Elizabeth Officer S-Sale D Series A Common Stock 10,780 9.13 98.5K 183,726 D
2025-07-21 Martins Eduardo Bruno Officer S-Sale D Series A Common Stock 8,277 9.13 75.6K 106,936 D
2025-07-21 Happel David Director / Officer S-Sale D Series A Common Stock 65,478 9.13 598.1K 689,722 D
2025-06-09 Walbert Timothy P Director A-Award A Stock Option (Right to Buy) 32,250 5.33 171.9K 32,250 D
2025-06-09 SEIDENBERG BETH C Director A-Award A Stock Option (Right to Buy) 32,250 5.33 171.9K 32,250 D
2025-06-09 Phillips Anne M. Director A-Award A Stock Option (Right to Buy) 27,268 5.33 145.3K 27,268 D
2025-06-09 Kemble George Director A-Award A Stock Option (Right to Buy) 32,250 5.33 171.9K 32,250 D
2025-06-09 Jarrett Jennifer Director A-Award A Stock Option (Right to Buy) 27,268 5.33 145.3K 27,268 D
2025-06-09 Hoelscher Paul W. Director A-Award A Stock Option (Right to Buy) 32,250 5.33 171.9K 32,250 D
2025-06-09 GRAMMER ELIZABETH A Director A-Award A Stock Option (Right to Buy) 32,250 5.33 171.9K 32,250 D
2025-06-06 SEIDENBERG BETH C Director A-Award A Stock Option (Right to Buy) 28,522 5.56 158.6K 28,522 D
2025-02-06 Rozek Elizabeth Officer A-Award A Stock Option (Right to Buy) 138,000 4.71 650.0K 138,000 D
2025-02-06 Martins Eduardo Bruno Officer A-Award A Series A Common Stock 34,000 0.00 115,213 D
2025-02-06 Happel David Director / Officer A-Award A Stock Option (Right to Buy) 472,000 4.71 2.22M 472,000 D
2025-02-06 Chauche Thierry Officer A-Award A Series A Common Stock 17,000 0.00 17,000 D
2024-08-01 Phillips Anne M. Director A-Award A Stock Option (Right to Buy) 113,895 3.48 396.4K 113,895
2024-08-01 Jarrett Jennifer Director A-Award A Stock Option (Right to Buy) 113,895 3.48 396.4K 113,895
2024-07-23 Kemble George Director / Officer S-Sale D Series A Common Stock 23,625 3.17 74.8K 118,693
2024-07-19 Rozek Elizabeth Officer S-Sale D Series A Common Stock 10,914 3.10 33.8K 160,506
2024-07-19 Martins Eduardo Bruno Officer S-Sale D Series A Common Stock 8,357 3.10 25.9K 81,213
2024-07-19 Kemble George Director / Officer S-Sale D Series A Common Stock 14,062 3.10 43.6K 142,318
2024-06-05 Walbert Timothy P Director A-Award A Stock Option (Right to Buy) 9,279 4.64 43.1K 9,279
2024-06-05 SEIDENBERG BETH C Director A-Award A Stock Option (Right to Buy) 51,459 4.64 238.8K 51,459
2024-06-05 Parsey Merdad Director A-Award A Stock Option (Right to Buy) 51,459 4.64 238.8K 51,459
2024-06-05 Hoelscher Paul W. Director A-Award A Stock Option (Right to Buy) 9,279 4.64 43.1K 9,279
2024-06-05 GRAMMER ELIZABETH A Director A-Award A Stock Option (Right to Buy) 51,459 4.64 238.8K 51,459
2024-05-06 Chauche Thierry Officer A-Award A Stock Option (Right to Buy) 587,181 4.28 2.51M 587,181
2024-04-01 Walbert Timothy P Director A-Award A Stock Option (Right to Buy) 73,014 5.23 381.9K 73,014
2024-04-01 Hoelscher Paul W. Director A-Award A Stock Option (Right to Buy) 73,014 5.23 381.9K 73,014
2024-03-26 Happel David Director / Officer P-Purchase A Series A Common Stock 12,100 5.27 63.7K 639,200
2024-01-29 SANDELL SCOTT D 10% Owner J-Other A Series A Common Stock 6,997 0.00 6,997
2024-01-29 NEW ENTERPRISE ASSOCIATES 13 LP 10% Owner J-Other D Series A Common Stock 850,000 0.00 3,000,275
2023-07-18 NEW ENTERPRISE ASSOCIATES 13 LP 10% Owner C-Conversion D Series C Preferred Stock 11,363,634 0.00 0
2023-07-18 GRAMMER ELIZABETH A Director D-Return D Stock Option (Right to Buy) 49,533 8.74 432.9K 0
2023-07-13 NEW ENTERPRISE ASSOCIATES 13 LP 10% Owner D Series B Preferred Stock 16,370 0.00 0
2023-07-13 GRAMMER ELIZABETH A Director D Stock Option (Right to Buy) 49,533 8.74 432.9K 0
2014-01-23 NEW ENTERPRISE ASSOCIATES 13 LP 10% Owner D Common Stock Warrant (right to buy) 13,404 0.79 10.7K 0

Executive team

Top executives
Shares Outstanding
32.58M

Executive compensation

Executive compensation (annual)
# Year Executive Salary Bonus Stock award Option award Incentive Other Total % Stock-
based
Filing
1 2025 David Happel President and Chief Executive Officer 630.0K 546.4K 1.75M 294.5K 19.4K 3.24M 70.87%
2 2025 Elizabeth Rozek, Esq. Chief Legal and Administrative Officer 483.3K 235.1K 591.7K 170.0K 16.6K 1.50M 55.24%
3 2025 Eduardo Bruno Martins, M.D., D.Phil., Former Chief Medical Officer 500.0K 160.1K 511.6K 170.0K 19.1K 1.36M 49.36%
4 2024 Thierry Chauche Chief Financial Officer 314.5K 1.97M 125.7K 506.00 2.41M 81.69%
5 2024 David Happel President and Chief Executive Officer 582.0K 320.1K 4.1K 906.2K 0.00%
6 2024 Eduardo Bruno Martins, M.D., D.Phil., Former Chief Medical Officer 475.0K 190.0K 4.1K 669.1K 0.00%
7 2024 Eduardo Bruno Martins, M.D., D.Phil., Chief Medical Officer 475.0K 190.0K 4.1K 669.1K 0.00%
8 2024 Elizabeth Rozek, Esq. Chief Legal and Administrative Officer 446.0K 178.4K 1.7K 626.1K 0.00%
9 2023 David Happel President and Chief Executive Officer 502.9K 1.85M 329.7K 3.6K 2.69M 68.87%
10 2023 Eduardo Bruno Martins, M.D., D.Phil., Chief Medical Officer 442.9K 265.1K 594.6K 202.8K 3.6K 1.51M 56.97%
11 2023 George Kemble, Ph.D. Executive Chairman and former President, Chief Executive Officer and Chief Scientific Officer 458.6K 446.2K 25.4K 930.2K 47.97%
12 2023 Dennis Hom Former Chief Financial Officer 226.1K 519.4K 745.5K 0.00%
13 2022 David Happel President and Chief Executive Officer 97.9K 6.20M 211.5K 297.00 6.51M 95.24%
14 2022 George Kemble, Ph.D. Executive Chairman and former President, Chief Executive Officer and Chief Scientific Officer 404.9K 129.7K 40.3K 574.9K 22.56%
15 2022 Eduardo Bruno Martins, M.D., D.Phil., Chief Medical Officer 411.1K 125.8K 297.00 537.1K 0.00%
16 2022 Dennis Hom Former Chief Financial Officer 357.5K 109.4K 68.00 466.9K 0.00%
CEO compensation breakdown

Proxy statements

Proxy statements (DEF 14A)
Filing date Form type Filing
2026-04-21 DEF 14A
2025-04-30 DEF 14A

Recent SEC filings

Recent SEC filings
Filing date Form type Filing
2026-05-14 4
2026-05-14 3
2026-05-12 8-K
2026-05-12 10-Q
2026-04-28 8-K
2026-04-28 424B5
2026-04-27 8-K
2026-04-27 8-K
2026-04-21 DEF 14A
2026-04-21 ARS

Executive team

NameTitleCompensationGender
David A. Happel Chief Executive Officer, President & Director 943.9K male
Elizabeth Rozek Chief Legal & Administrative Officer 669.9K female
Eduardo Bruno Martins DPhil Chief Medical Officer 669.1K
Andreas Grauer Chief Medical Officer 669.1K
Thierry Chauche Chief Financial Officer & Principal Accounting Officer 598.0K male
Urs Greber Co-Founder male
Lucas Pelkmans Co-Founder
Marie O'Farrell Chief Scientific Officer
Robert D'Urso Senior Vice President of New Products male
ESG Rating
B
BIOTECHNOLOGY
Rank: 326 out of 714
2026
E (Environmental)
64.0 / 56.3
Company / Sector avg.
S (Social)
66.7 / 62.4
Company / Sector avg.
G (Governance)
63.7 / 60.9
Company / Sector avg.
ESG Total
64.8 / 59.9
Company / Sector avg.
ESG Score History BIOTECHNOLOGY
Benchmark vs Sector
Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend history

Earnings history

Earnings reports

Stock splits