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Sana Biotechnology, Inc. (SANA)

USD3.15 +0.11 (+3.62%)
US NASDAQ Healthcare Biotechnology
Address 188 East Blaine Street 98102
Seattle, WA, US
CEO Steven D. Harr
Website sana.com
IPO 2021-02-04
CIK 1770121 ISIN US7995661045

Explore sections of this company profile

Description

Sana Biotechnology, Inc. is a biotechnology firm focused on creating treatments using engineered cells. The company develops advanced ex vivo and in vivo cell engineering platforms to address a range of conditions with significant unmet medical needs, including various cancers, diabetes, central nervous system disorders, cardiovascular diseases, and genetic illnesses. Its portfolio of drug candidates includes SG295 and SG242, which are designed to target CD19+ cancer cells involved in non-Hodgkin Lymphoma, chronic lymphocytic leukemia, and acute lymphoblastic leukemia. For multiple myeloma, Sana is progressing SG221, SG239, and SC255. Other pipeline assets include SG328 for ornithine transcarbamylase deficiency, and SG418 for sickle cell disease and beta-thalassemia. Additionally, the company is advancing SC291, a CD19 allogeneic T cell therapy, SC451 for type I diabetes mellitus, and SC379 for secondary progressive multiple sclerosis, Pelizaeus-Merzbacher disease, and Huntington's disease. Founded in 2018 as FD Therapeutics, Inc., the company adopted its current name, Sana Biotechnology, Inc., in September 2018 and is based in Seattle, Washington.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
USD3.15 +0.11 (+3.62%)
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Volume Profile
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Liquidity & share structure
Average Volume
4M
Beta
2.16
Float Shares
169.91M
Free Float %
61.1%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
+5.43% +7.14% +0.30% -21.62% -23.26% -18.92% +50.00% -45.18% -84.38% -90.60% -90.60%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
vs.
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Analyst Consensus (11 ratings, all time) Buy
Price Targets & DCF
Current price
3.15
Low 7.00 +122.2%
Consensus 8.67 +175.2%
Median 7.00 +122.2%
High 12.00 +281.0%
Ratings Trend (MoM) 89% Bullish
Rating 2026-05 Change
Strong Buy 2 0
Buy 6 0
Hold 1 0
Sell 0 0
Strong Sell 0 0
Price Target Summary
Period # Analysts Avg Target
Last Month
Last Quarter 3
8.67
+175.2%
Last Year 4
8.50
+169.8%
All Time 6
9.00
+185.7%
Quality scores
Altman Z-Score
-6.67
Distress
Piotroski F-Score
1 / 9
Weak
MOAT Score
3 / 10
No MOAT
Composite Rating
D+
Overall Score
1 / 5
Low
DCF Score
1 / 5
Low
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
1 / 5
Low
P/E Score
1 / 5
Low
P/Book Score
1 / 5
Low
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
  • EPS growth Biotechnology: +29.7%
    +17.2% Q1'26: +19.0% (vs Q1'25)
  • FCF margin FCF growth · Biotechnology: +16.2%
  • EBIT margin Biotechnology: +0.0%
  • ROIC Biotechnology: -16.1%
    -188.4% Q1'26: -162.1% (vs Q1'25)
  • Share dilution Biotechnology: -3.4%
    +9.7% Q1'26: +16.5% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    -0.44× Q1'26: -0.53× (vs Q1'25)
Valuation Multiples From To
DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (2.18) × ERP
WACC = 91% × Ke + 9% × Kd (4.1%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Current price: 3.15
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2024
actual
Dec 2025
actual
Dec 2026
6 EPS Ana.
Dec 2027
6 Rev. Ana.
5 EPS Ana.
Dec 2028
5 Rev. Ana.
6 EPS Ana.
Dec 2029
2 Rev. Ana.
4 EPS Ana.
Dec 2030
2 Rev. Ana.
2 EPS Ana.
Revenue
— – —
6.95M
6.95M – 6.95M
19.80M
19.80M – 19.80M
+184.9% YoY
4.98M
4.98M – 4.98M
-74.9% YoY
26.25M
26.25M – 26.25M
+427.6% YoY
EBITDA
-255.33M
-178.21M
— – —
— – —
— – —
— – —
— – —
EBIT
-272.72M
-190.96M
— – —
— – —
— – —
— – —
— – —
Net Income
-266.76M
est: -274.97M (+3.0%)
-244.17M
est: -218.56M (-11.7%)
-154.95M
-169.94M – -139.95M
+29.1% YoY
-135.60M
-161.68M – -109.52M
+12.5% YoY
-140.36M
-181.50M – -99.22M
-3.5% YoY
-172.20M
-172.20M – -172.20M
-22.7% YoY
-157.64M
-157.64M – -157.64M
+8.5% YoY
SGA
64.04M
44.30M
— – —
— – —
— – —
— – —
— – —
EPS
-1.16
est: -1.19 (+2.2%)
-0.96
est: -0.86 (-11.2%)
-0.61
-0.67 – -0.55
+29.1% YoY
-0.58
-0.64 – -0.43
+5.8% YoY
-0.59
-0.72 – -0.39
-2.7% YoY
-0.68
-0.68 – -0.68
-14.8% YoY
-0.62
-0.62 – -0.62
+8.5% YoY
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-28 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-27 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-26 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-22 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-21 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-20 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-19 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-18 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-15 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-14 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-13 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-12 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-11 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-08 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-07 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-06 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-05 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-04 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-01 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-30 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-29 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-28 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-27 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-24 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-23 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-22 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-21 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-20 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-17 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-16 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5

Owner Earnings

Owner's Earnings (history)

Owner's Earnings history not available.

Owner alignment
Owner's Earnings TTM
OE per share TTM
Owner's Yield
Maintenance CapEx ratio
Maint CapEx / Avg PPE

Ownership Overview

Ownership breakdown
At a glance
Institutional holders
204
Total invested
472.64M
Insider transactions (90d)
0
Beneficial owners (>5%)
18
Beneficial owners (>5%)
# Reporting person Amount owned % of class Sole voting Shared voting Sole dispositive Shared dispositive Type Citizenship Filing date SEC filing
1 Robert Nelsen 44.08M 23.30% 36.1K 44.04M 36.1K 44.04M IN United States of America 2022-02-10
2 ARCH Venture Fund IX Overage, L.P. 44.04M 23.30% 44.04M 44.04M PN Delaware 2022-02-10
3 ARCH Venture Fund IX, L.P. 44.04M 23.30% 44.04M 44.04M PN Delaware 2022-02-10
4 ARCH Venture Fund X Overage, L.P. 44.04M 23.30% 44.04M 44.04M PN Delaware 2022-02-10
5 ARCH Venture Fund X, L.P. 44.04M 23.30% 44.04M 44.04M PN Delaware 2022-02-10
6 ARCH Venture Partners IX Overage, L.P. 44.04M 23.30% 44.04M 44.04M PN Delaware 2022-02-10
7 ARCH Venture Partners IX, L.P. 44.04M 23.30% 44.04M 44.04M PN Delaware 2022-02-10
8 ARCH Venture Partners X Overage, L.P. 44.04M 23.30% 44.04M 44.04M PN Delaware 2022-02-10
9 ARCH Venture Partners X, L.P. 44.04M 23.30% 44.04M 44.04M PN Delaware 2022-02-10
10 Clinton Bybee 44.04M 23.30% 44.04M 44.04M IN United States of America 2022-02-10
11 Crandell 44.04M 23.30% 44.04M 44.04M IN United States of America 2022-02-10
12 Kristina Burow 44.04M 23.30% 44.04M 44.04M IN United States of America 2022-02-10
13 Steven Gillis 44.04M 23.30% 44.04M 44.04M IN United States of America 2022-02-10
14 (1) BlackRock, Inc. 11.82M 5.30% 11.82M HC Delaware 2024-10-22
15 Baillie Gifford & Co (Scottish partnership) 11.26M 11.00% IA SCOTLAND UK 2022-01-26
16 Canada Pension Plan Investment Board 10.18M 5.40% 10.18M FI : 2022-02-14
17 Abigail P. Johnson 9.71M 5.07% 9.71M IN Delaware 2023-04-26
18 FMR LLC 9.71M 5.07% 9.70M 9.71M HC Delaware 2023-04-26

Institutional Activity (13F)

Institutional ownership trend From To
13F snapshot — 2026 Q1
Investors holding
204
-4 vs prev Q
New positions
30
Closed positions
34
Increased
97
Reduced
54
Put/Call ratio
0.44
Calls held
337.2K
Puts held
148.5K
Top institutional holders
# Investor Shares / Δ Mkt value / Δ Own% / Δ Weight% / Δ Avg px / Perf. Hold / Status
1 64.9K +64.9K (+100.0%) 264.17M +264.2M (+100.0%) 0.02% +0.025 pp 0.10% +0.104 pp USD4.07 +0.0% 1 qtrs NEW
2 FMR LLC 37.43M -1.1K (0.0%) 152.34M +19.5M (+14.6%) 14.37% -1.332 pp 0.01% +0.001 pp USD11.49 -64.6% 20 qtrs
3 FLAGSHIP PIONEERING INC. 25.00M +— (+0.0%) 101.76M +13.0M (+14.6%) 9.60% -0.889 pp 31.40% +1.071 pp USD33.47 -87.8% 20 qtrs
4 BLACKROCK, INC. 14.22M +3.0M (+26.7%) 57.89M +18.0M (+45.3%) 5.46% +0.751 pp 0.00% +0.000 pp USD4.11 -1.0% 6 qtrs
5 VANGUARD GROUP INC 10.46M +1.3M (+14.5%) 42.55M +10.1M (+31.3%) 4.01% +0.185 pp 0.00% +0.000 pp USD14.09 -71.1% 20 qtrs
6 CANADA PENSION PLAN INVESTMENT BOARD 10.24M +67.1K (+0.7%) 41.69M +5.6M (+15.4%) 3.93% -0.336 pp 0.03% +0.003 pp USD33.28 -87.8% 20 qtrs
7 STATE STREET CORP 8.05M +1.4M (+20.6%) 32.78M +9.1M (+38.2%) 3.09% +0.290 pp 0.00% +0.000 pp USD6.01 -32.3% 20 qtrs
8 BAILLIE GIFFORD & CO 6.61M -4.8M (-42.2%) 26.90M -13.7M (-33.7%) 2.54% -2.260 pp 0.02% -0.008 pp USD27.28 -85.1% 20 qtrs
9 GEODE CAPITAL MANAGEMENT, LLC 4.12M +694.6K (+20.3%) 16.76M +4.6M (+37.9%) 1.58% +0.145 pp 0.00% +0.000 pp USD12.27 -66.8% 20 qtrs
10 MAREX GROUP PLC 3.73M -90.0K (-2.4%) 15.19M +1.6M (+11.9%) 1.43% -0.171 pp 0.10% 0.000 pp USD2.73 +49.1% 3 qtrs
11 INTEGRAL HEALTH ASSET MANAGEMENT, LLC 3.00M +1.0M (+50.0%) 12.21M +5.1M (+72.0%) 1.15% +0.313 pp 0.61% +0.126 pp USD5.43 -25.0% 8 qtrs
12 ALPHABET INC. 2.81M +— (+0.0%) 11.45M +1.5M (+14.6%) 1.08% -0.100 pp 0.44% +0.029 pp USD33.47 -87.8% 20 qtrs
13 RENAISSANCE TECHNOLOGIES LLC 1.69M -301.4K (-15.1%) 6.88M -190.5K (-2.7%) 0.65% -0.187 pp 0.01% +0.001 pp USD3.47 +17.3% 19 qtrs
14 BALYASNY ASSET MANAGEMENT L.P. 1.68M +1.7M (+100.0%) 6.83M +6.8M (+100.0%) 0.64% +0.645 pp 0.01% +0.009 pp USD4.07 +0.0% 1 qtrs NEW
15 TWO SIGMA INVESTMENTS, LP 1.58M +969.6K (+158.9%) 6.43M +4.3M (+196.8%) 0.61% +0.351 pp 0.01% +0.006 pp USD3.56 +14.3% 17 qtrs
16 GOLDMAN SACHS GROUP INC 1.49M +806.3K (+118.2%) 6.06M +3.6M (+150.2%) 0.57% +0.285 pp 0.00% +0.000 pp USD4.51 -9.8% 20 qtrs
17 NORTHERN TRUST CORP 1.41M +89.2K (+6.8%) 5.73M +1.0M (+22.4%) 0.54% -0.013 pp 0.00% +0.000 pp USD12.81 -68.2% 20 qtrs
18 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 1.40M +126.8K (+10.0%) 5.70M +1.2M (+26.1%) 0.54% +0.003 pp 0.00% +0.000 pp USD12.32 -67.0% 20 qtrs
19 WOODLINE PARTNERS LP 1.32M -60.6K (-4.4%) 5.36M +470.1K (+9.6%) 0.51% -0.072 pp 0.02% -0.002 pp USD6.31 -35.5% 20 qtrs
20 MORGAN STANLEY 1.29M +408.5K (+46.6%) 5.23M +2.1M (+68.1%) 0.49% +0.126 pp 0.00% +0.000 pp USD5.90 -31.0% 20 qtrs
21 CRESTLINE MANAGEMENT, LP 1.22M -600.0K (-33.0%) 4.97M -1.5M (-23.1%) 0.47% -0.295 pp 9.32% -1.810 pp USD18.45 -77.9% 19 qtrs
22 BANK OF AMERICA CORP /DE/ 1.19M +268.6K (+29.3%) 4.83M +1.6M (+48.2%) 0.46% +0.071 pp 0.00% +0.000 pp USD4.38 -7.1% 20 qtrs
23 UBS GROUP AG 1.18M -261.0K (-18.1%) 4.81M -311.5K (-6.1%) 0.45% -0.152 pp 0.00% +0.000 pp USD3.12 +30.4% 20 qtrs
24 AQR CAPITAL MANAGEMENT LLC 1.13M -47.5K (-4.0%) 4.62M +421.4K (+10.0%) 0.44% -0.060 pp 0.00% 0.000 pp USD2.41 +68.9% 9 qtrs
25 OMEGA FUND MANAGEMENT, LLC 843.8K +— (+0.0%) 3.43M +438.8K (+14.6%) 0.32% -0.030 pp 1.20% -0.149 pp USD33.47 -87.8% 20 qtrs
26 JPMORGAN CHASE & CO 815.5K -1.3M (-61.8%) 3.32M -4.3M (-56.2%) 0.31% -0.583 pp 0.00% 0.000 pp USD10.62 -61.7% 20 qtrs
27 PRICE T ROWE ASSOCIATES INC /MD/ 766.5K +620.4K (+424.6%) 3.12M +2.6M (+501.3%) 0.29% +0.233 pp 0.00% +0.000 pp USD5.11 -20.4% 20 qtrs
28 GREAT POINT PARTNERS LLC 700.0K +— (+0.0%) 2.85M +364.0K (+14.6%) 0.27% -0.025 pp 0.92% -0.101 pp USD3.55 +14.6% 2 qtrs
29 ARROWMARK COLORADO HOLDINGS LLC 685.1K +— (+0.0%) 2.79M +356.3K (+14.6%) 0.26% -0.024 pp 0.06% +0.016 pp USD3.94 +3.3% 10 qtrs
30 JANE STREET GROUP, LLC 668.9K +438.3K (+190.0%) 2.72M +1.9M (+232.5%) 0.26% +0.160 pp 0.00% +0.000 pp USD3.74 +8.8% 15 qtrs
31 CI PRIVATE WEALTH, LLC 638.4K -178.6K (-21.9%) 2.60M -302.2K (-10.4%) 0.25% -0.098 pp 0.00% -0.001 pp USD2.77 +46.9% 13 qtrs
32 MILLENNIUM MANAGEMENT LLC 623.2K -996.8K (-61.5%) 2.54M -3.2M (-55.9%) 0.24% -0.440 pp 0.00% -0.001 pp USD3.03 +34.3% 17 qtrs
33 DEUTSCHE BANK AG\ 562.3K +19.0K (+3.5%) 2.29M +359.9K (+18.7%) 0.22% -0.012 pp 0.00% +0.000 pp USD6.00 -32.2% 20 qtrs
34 INVESCO LTD. 561.8K +109.1K (+24.1%) 2.29M +679.4K (+42.3%) 0.22% +0.026 pp 0.00% +0.000 pp USD3.20 +27.2% 20 qtrs
35 SUSQUEHANNA INTERNATIONAL GROUP, LLP 559.8K +46.2K (+9.0%) 2.28M +455.2K (+25.0%) 0.21% -0.001 pp 0.00% +0.000 pp USD2.98 +36.6% 19 qtrs
36 BARCLAYS PLC 509.9K +191.0K (+59.9%) 2.08M +748.6K (+56.4%) 0.20% +0.062 pp 0.00% +0.000 pp USD3.76 +8.2% 16 qtrs
37 BANK OF NEW YORK MELLON CORP 457.2K +51.6K (+12.7%) 1.86M +420.8K (+29.2%) 0.18% +0.005 pp 0.00% +0.000 pp USD12.91 -68.5% 20 qtrs
38 SWISS NATIONAL BANK 335.8K +73.5K (+28.0%) 1.37M +435.5K (+46.8%) 0.13% +0.019 pp 0.00% +0.000 pp USD3.66 +11.2% 17 qtrs
39 SQUAREPOINT OPS LLC 331.7K +109.4K (+49.2%) 1.35M +560.9K (+71.1%) 0.13% +0.034 pp 0.00% +0.001 pp USD3.92 +3.8% 17 qtrs
40 NUVEEN, LLC 325.2K +21.2K (+7.0%) 1.32M +244.3K (+22.6%) 0.12% -0.003 pp 0.00% +0.000 pp USD1.84 +121.2% 4 qtrs
41 BAKER BROS. ADVISORS LP 310.5K -1.7M (-84.7%) 1.26M -5.9M (-82.5%) 0.12% -0.733 pp 0.01% -0.045 pp USD4.37 -6.9% 12 qtrs
42 PRIVATE ADVISOR GROUP, LLC 309.4K +309.4K (+100.0%) 1.26M +1.3M (+100.0%) 0.12% +0.119 pp 0.01% +0.006 pp USD4.07 +0.0% 1 qtrs NEW
43 DEKABANK DEUTSCHE GIROZENTRALE 112.3K +— (+0.0%) 1.22M +13.0K (+1.1%) 0.04% -0.004 pp 0.00% +0.000 pp USD15.82 -74.3% 19 qtrs
44 RAFFERTY ASSET MANAGEMENT, LLC 274.2K +6.2K (+2.3%) 1.12M +164.5K (+17.3%) 0.11% -0.007 pp 0.00% +0.001 pp USD3.56 +14.3% 19 qtrs
45 UBS ASSET MANAGEMENT AMERICAS INC 240.4K +99.8K (+70.9%) 978.5K +479.2K (+96.0%) 0.09% +0.033 pp 0.00% +0.000 pp USD3.77 +8.0% 17 qtrs
46 IEQ CAPITAL, LLC 236.7K -3.2K (-1.3%) 963.3K +111.8K (+13.1%) 0.09% -0.010 pp 0.00% +0.000 pp USD2.27 +79.3% 5 qtrs
47 TWO SIGMA ADVISERS, LP 221.7K +221.7K (+100.0%) 902.2K +902.2K (+100.0%) 0.09% +0.085 pp 0.00% +0.002 pp USD4.07 +0.0% 17 qtrs
48 CITADEL ADVISORS LLC 207.9K +105.9K (+103.8%) 846.2K +484.1K (+133.7%) 0.08% +0.037 pp 0.00% +0.000 pp USD3.61 +12.7% 15 qtrs
49 WELLS FARGO & COMPANY/MN 191.1K +84.7K (+79.6%) 777.7K +400.1K (+106.0%) 0.07% +0.029 pp 0.00% +0.000 pp USD3.70 +10.0% 20 qtrs
50 RHUMBLINE ADVISERS 189.4K -6.3K (-3.2%) 770.9K +76.2K (+11.0%) 0.07% -0.009 pp 0.00% +0.000 pp USD12.91 -68.5% 20 qtrs
51 ALLIANCEBERNSTEIN L.P. 186.9K -9.8K (-5.0%) 760.9K +62.4K (+8.9%) 0.07% -0.011 pp 0.00% +0.000 pp USD12.89 -68.4% 20 qtrs
52 SUSQUEHANNA PORTFOLIO STRATEGIES, LLC 167.5K +— (+0.0%) 681.7K +87.1K (+14.6%) 0.06% -0.006 pp 0.01% +0.001 pp USD2.73 +49.1% 3 qtrs
53 CLARIUS GROUP, LLC 166.1K -46.4K (-21.9%) 675.9K -78.5K (-10.4%) 0.06% -0.025 pp 0.04% -0.006 pp USD3.38 +20.4% 19 qtrs
54 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 164.8K +36.1K (+28.1%) 670.7K +213.9K (+46.8%) 0.06% +0.009 pp 0.00% +0.000 pp USD4.28 -4.9% 20 qtrs
55 VOYA INVESTMENT MANAGEMENT LLC 163.5K +138.5K (+554.1%) 665.6K +576.8K (+649.9%) 0.06% +0.052 pp 0.00% +0.001 pp USD5.20 -21.7% 20 qtrs
56 CITIGROUP INC 154.8K +70.0K (+82.7%) 629.9K +329.1K (+109.4%) 0.06% +0.024 pp 0.00% +0.000 pp USD4.01 +1.5% 20 qtrs
57 LEGAL & GENERAL GROUP PLC 151.0K +21.8K (+16.8%) 614.6K +155.8K (+33.9%) 0.06% +0.004 pp 0.00% +0.000 pp USD5.10 -20.2% 20 qtrs
58 DIMENSIONAL FUND ADVISORS LP 133.1K -645.0K (-82.9%) 541.6K -2.2M (-80.4%) 0.05% -0.275 pp 0.00% -0.001 pp USD5.24 -22.3% 15 qtrs
59 MIRAE ASSET GLOBAL ETFS HOLDINGS LTD. 130.3K -34.8K (-21.1%) 530.4K -55.6K (-9.5%) 0.05% -0.019 pp 0.00% 0.000 pp USD5.37 -24.2% 7 qtrs
60 STATE OF WISCONSIN INVESTMENT BOARD 128.9K -69.3K (-35.0%) 524.4K -179.1K (-25.5%) 0.05% -0.034 pp 0.00% 0.000 pp USD3.55 +14.6% 19 qtrs
61 PALUMBO WEALTH MANAGEMENT LLC 121.0K +9.7K (+8.7%) 492.4K +97.3K (+24.6%) 0.05% 0.000 pp 0.12% -0.005 pp USD3.04 +33.9% 3 qtrs
62 VIRTU FINANCIAL LLC 119.3K +78.1K (+189.4%) 486.0K +340.0K (+232.9%) 0.05% +0.029 pp 0.02% +0.011 pp USD3.73 +9.1% 3 qtrs
63 XTX TOPCO LTD 117.4K +10.6K (+9.9%) 477.7K +98.6K (+26.0%) 0.05% +0.000 pp 0.01% -0.007 pp USD3.60 +13.1% 2 qtrs
64 PROFUND ADVISORS LLC 102.0K +44.3K (+76.8%) 415.3K +210.4K (+102.7%) 0.04% +0.015 pp 0.01% +0.006 pp USD3.78 +7.7% 12 qtrs
65 SG AMERICAS SECURITIES, LLC 98.3K -2.0K (-2.0%) 400.0K +44.0K (+12.4%) 0.04% -0.004 pp 0.00% -0.001 pp USD1.97 +106.6% 5 qtrs
66 GILDER GAGNON HOWE & CO LLC 94.1K +2.5K (+2.8%) 382.9K +57.9K (+17.8%) 0.04% -0.002 pp 0.00% +0.001 pp USD3.56 +14.3% 2 qtrs
67 METLIFE INVESTMENT MANAGEMENT, LLC 93.1K +14.1K (+17.9%) 379.0K +98.6K (+35.1%) 0.04% +0.003 pp 0.00% +0.001 pp USD5.15 -21.0% 20 qtrs
68 HSBC HOLDINGS PLC 94.1K +15.8K (+20.2%) 374.8K +105.7K (+39.3%) 0.04% +0.003 pp 0.00% +0.000 pp USD3.34 +21.9% 10 qtrs
69 MANUFACTURERS LIFE INSURANCE COMPANY, THE 92.0K +44.5K (+93.6%) 374.7K +206.1K (+122.2%) 0.04% +0.015 pp 0.00% +0.000 pp USD6.26 -35.0% 19 qtrs
70 MARSHALL WACE, LLP 88.8K +88.8K (+100.0%) 361.4K +361.4K (+100.0%) 0.03% +0.034 pp 0.00% +0.000 pp USD4.07 +0.0% 1 qtrs NEW
71 CWM, LLC 85.1K -9.0 (0.0%) 346.0K +44.0K (+14.6%) 0.03% -0.003 pp 0.00% +0.000 pp USD2.26 +80.1% 5 qtrs
72 ZURCHER KANTONALBANK (ZURICH CANTONALBANK) 82.4K +33.0K (+66.7%) 335.3K +159.9K (+91.1%) 0.03% +0.011 pp 0.00% +0.000 pp USD3.76 +8.2% 17 qtrs
73 SCS CAPITAL MANAGEMENT LLC 81.3K -70.0 (-0.1%) 330.7K +42.0K (+14.5%) 0.03% -0.003 pp 0.00% +0.000 pp USD1.68 +142.3% 4 qtrs
74 TD ASSET MANAGEMENT INC 80.6K +80.6K (+100.0%) 328.0K +328.0K (+100.0%) 0.03% +0.031 pp 0.00% +0.000 pp USD4.07 +0.0% 20 qtrs
75 VIRGINIA RETIREMENT SYSTEMS ET AL 77.4K +77.4K (+100.0%) 314.8K +314.8K (+100.0%) 0.03% +0.030 pp 0.00% +0.002 pp USD4.07 +0.0% 1 qtrs NEW
76 BREVAN HOWARD CAPITAL MANAGEMENT LP 70.6K +70.6K (+100.0%) 287.4K +287.4K (+100.0%) 0.03% +0.027 pp 0.00% +0.003 pp USD4.07 +0.0% 7 qtrs
77 FRANKLIN RESOURCES INC 69.4K -23.7K (-25.4%) 282.5K -48.0K (-14.5%) 0.03% -0.012 pp 0.00% +0.000 pp USD3.44 +18.3% 11 qtrs
78 NEWEDGE ADVISORS, LLC 64.4K -33.2K (-34.0%) 262.1K -84.5K (-24.4%) 0.02% -0.016 pp 0.00% -0.001 pp USD3.26 +24.8% 4 qtrs
79 D. E. SHAW & CO., INC. 60.9K +60.9K (+100.0%) 247.9K +247.9K (+100.0%) 0.02% +0.023 pp 0.00% +0.000 pp USD4.07 +0.0% 6 qtrs
80 CREATIVE PLANNING 60.9K +6.7K (+12.4%) 247.9K +55.5K (+28.9%) 0.02% +0.001 pp 0.00% +0.000 pp USD2.00 +103.5% 5 qtrs
81 QUINN OPPORTUNITY PARTNERS LLC 60.1K -60.0K (-50.0%) 244.6K -181.7K (-42.6%) 0.02% -0.027 pp 0.01% -0.020 pp USD1.68 +142.3% 4 qtrs
82 ALGERT GLOBAL LLC 60.0K +60.0K (+100.0%) 244.0K +244.0K (+100.0%) 0.02% +0.023 pp 0.00% +0.004 pp USD4.07 +0.0% 1 qtrs NEW
83 SRS CAPITAL ADVISORS, INC. 59.0K -106.1K (-64.3%) 240.2K -365.9K (-60.4%) 0.02% -0.047 pp 0.01% -0.002 pp USD3.55 +14.6% 2 qtrs
84 JANUS HENDERSON GROUP PLC 58.2K +— (+0.0%) 236.5K +30.3K (+14.7%) 0.02% -0.002 pp 0.00% +0.000 pp USD3.55 +14.6% 16 qtrs
85 BIT CAPITAL GMBH 58.0K +58.0K (+100.0%) 236.1K +236.1K (+100.0%) 0.02% +0.022 pp 0.01% +0.009 pp USD4.07 +0.0% 1 qtrs NEW
86 WEALTH ENHANCEMENT ADVISORY SERVICES, LLC 53.1K +199.0 (+0.4%) 231.4K +13.6K (+6.2%) 0.02% -0.002 pp 0.00% +0.000 pp USD2.17 +87.6% 4 qtrs
87 SCHONFELD STRATEGIC ADVISORS LLC 55.8K +55.8K (+100.0%) 227.3K +227.3K (+100.0%) 0.02% +0.021 pp 0.00% +0.001 pp USD4.07 +0.0% 1 qtrs NEW
88 AXQ CAPITAL, LP 55.4K +37.2K (+204.0%) 225.5K +160.8K (+248.5%) 0.02% +0.014 pp 0.05% +0.026 pp USD3.63 +12.1% 3 qtrs
89 MODUS ADVISORS, LLC 55.0K +55.0K (+100.0%) 223.9K +223.9K (+100.0%) 0.02% +0.021 pp 0.06% +0.059 pp USD4.07 +0.0% 1 qtrs NEW
90 INTECH INVESTMENT MANAGEMENT LLC 53.3K -19.4K (-26.6%) 216.9K -41.0K (-15.9%) 0.02% -0.010 pp 0.00% 0.000 pp USD2.69 +51.3% 6 qtrs
91 VIRTUS INVESTMENT ADVISERS, INC. 51.8K +7.0K (+15.5%) 210.6K +51.6K (+32.5%) 0.02% +0.001 pp 0.06% +0.012 pp USD2.28 +78.5% 4 qtrs
92 ARIZONA STATE RETIREMENT SYSTEM 47.3K +7.4K (+18.4%) 192.7K +50.7K (+35.7%) 0.02% +0.001 pp 0.00% +0.000 pp USD3.63 +12.1% 17 qtrs
93 POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY 44.2K +7.5K (+20.5%) 180.1K +49.7K (+38.1%) 0.02% +0.002 pp 0.00% +0.000 pp USD2.48 +64.1% 5 qtrs
94 CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD. 43.4K -1.9K (-4.3%) 176.7K +15.7K (+9.7%) 0.02% -0.002 pp 0.01% +0.000 pp USD5.40 -24.6% 14 qtrs
95 CERITY PARTNERS LLC 42.4K +279.0 (+0.7%) 172.6K +23.0K (+15.4%) 0.02% -0.001 pp 0.00% +0.000 pp USD1.68 +142.3% 5 qtrs
96 COLONY GROUP, LLC 42.2K +11.4K (+37.3%) 171.6K +62.6K (+57.4%) 0.02% +0.003 pp 0.00% +0.000 pp USD2.45 +66.1% 8 qtrs
97 PROSHARE ADVISORS LLC 42.1K +10.1K (+31.5%) 171.5K +57.7K (+50.8%) 0.02% +0.003 pp 0.00% +0.000 pp USD7.73 -47.3% 18 qtrs
Ownership breakdown by holder

ETF Ownership

Top ETFs holding this stock Held by 85 ETFs in our universe
# ETF Weight Est. AUM exposure TER
1 Virtus Biotech Clinical Trials ETF BBC 0.88% 509.0K 0.65%
2 WisdomTree BioRevolution UCITS ETF - USD Acc WDNA.L 0.70% 156.0K 0.45%
3 Global X - S&P Biotech ETF CURE.AX 0.25% 91.0K 0.45%
4 State Street SPDR S&P Biotech ETF XBI 0.25% 27.32M 0.35%
5 iShares Nasdaq US Biotechnology UCITS ETF BTEC.L 0.07% 814.3K 0.35%
6 iShares Nasdaq US Biotechnology UCITS ETF BTEE.L 0.07% 54.5K 0.35%
7 Invesco NASDAQ Biotech UCITS ETF SBIO.L 0.07% 341.0K 0.40%
8 Invesco Nasdaq Biotechnology ETF IBBQ 0.07% 55.0K 0.19%
9 Innovator U.S. Small Cap Managed Floor ETF RFLR 0.06% 50.9K 0.89%
10 iShares Biotechnology ETF IBB 0.05% 5.01M 0.44%

Insider Activity

Insider Activity — Latest Quarter
Ratio by transactions
1.08
Neutral
Ratio by volume
3.00
Bullish
Buys
13
Sells
12
Shares acquired
2.57M
Shares disposed
146.0K
Cash buys
Cash sales
Net activity
+2,426,610
Insider buys vs sells (history) From To
Recent insider transactions From To
Date Person Role Transaction A/D Security Shares Price Value Owned after D/I Filing
2026-04-06 Bishop Hans Edgar Director A-Award A Common Stock 7,763 0.00 5,848,503 D
2026-03-24 PATEL DHAVALKUMAR DHIRAJLAL Officer Common Stock 0 0.00 99,510 D
2026-03-09 Wyrick Susan D. Officer F-InKind D Common Stock 1,045 3.10 3.2K 196,196 D
2026-03-09 Harr Steve Director / Officer F-InKind D Common Stock 11,526 3.13 36.1K 7,957,070 D
2026-03-07 Wyrick Susan D. Officer M-Exempt A Common Stock 3,250 0.00 200,583 D
2026-03-07 Harr Steve Director / Officer M-Exempt D Restricted Stock Units 50,000 0.00 100,000 D
2026-03-06 Wyrick Susan D. Officer M-Exempt D Restricted Stock Units 10,416 0.00 31,251 D
2026-03-06 Harr Steve Director / Officer M-Exempt D Restricted Stock Units 41,666 0.00 125,001 D
2026-03-05 Wyrick Susan D. Officer A-Award A Stock Option (Right to Buy) 206,250 3.41 703.3K 206,250 D
2026-03-05 Harr Steve Director / Officer A-Award A Restricted Stock Units 200,000 0.00 200,000 D
2026-03-03 Wyrick Susan D. Officer F-InKind D Common Stock 491 3.91 1.9K 186,917 D
2026-03-02 Wyrick Susan D. Officer M-Exempt A Common Stock 1,525 0.00 187,408 D
2026-02-17 Piper Brian Officer A-Award A Stock Option (Right to Buy) 900,000 3.85 3.47M 900,000 D
2026-01-05 Wyrick Susan D. Officer F-InKind D Common Stock 2,407 4.27 10.3K 185,883 D
2026-01-05 Bishop Hans Edgar Director A-Award A Common Stock 6,157 0.00 5,840,740 D
2026-01-02 Wyrick Susan D. Officer M-Exempt A Common Stock 7,500 0.00 188,290 D
2025-12-15 Wyrick Susan D. Officer F-InKind D Common Stock 873 5.22 4.6K 180,790 D
2025-12-13 Wyrick Susan D. Officer M-Exempt A Common Stock 3,400 0.00 181,663 D
2025-12-04 Wyrick Susan D. Officer F-InKind D Common Stock 2,565 4.44 11.4K 178,263 D
2025-12-03 Wyrick Susan D. Officer M-Exempt D Restricted Stock Units 10,000 0.00 0 D
2025-10-06 Bishop Hans Edgar Director A-Award A Common Stock 5,628 0.00 5,834,583 D
2025-07-07 Bishop Hans Edgar Director A-Award A Common Stock 7,842 0.00 5,828,955 D
2025-06-05 Yang Patrick Y Director A-Award A Stock Option (Right to Buy) 80,000 2.55 204.0K 80,000 D
2025-06-05 Wilderotter Mary Agnes Director A-Award A Stock Option (Right to Buy) 80,000 2.55 204.0K 80,000 D
2025-06-05 Seitz Michelle Director A-Award A Stock Option (Right to Buy) 80,000 2.55 204.0K 80,000 D
2025-06-05 Rosiello Robert L. 0 0.00 0
2025-06-05 REICIN ALISE Director A-Award A Stock Option (Right to Buy) 80,000 2.55 204.0K 80,000 D
2025-06-05 NELSEN ROBERT Director / 10% Owner A-Award A Stock Option (Right to Buy) 80,000 2.55 204.0K 80,000 D
2025-06-05 Mulligan Richard Director A-Award A Stock Option (Right to Buy) 80,000 2.55 204.0K 80,000 D
2025-06-05 Bishop Hans Edgar Director A-Award A Stock Option (Right to Buy) 80,000 2.55 204.0K 80,000 D
2025-06-05 Bilenker Joshua H. Director A-Award A Stock Option (Right to Buy) 80,000 2.55 204.0K 80,000 D
2025-06-04 Wyrick Susan D. Officer F-InKind D Common Stock 2,567 2.32 6.0K 167,828 D
2025-06-03 Wyrick Susan D. Officer M-Exempt A Common Stock 10,000 0.00 170,395 D
2025-04-07 Bishop Hans Edgar Director A-Award A Common Stock 16,339 0.00 5,821,113 D
2025-03-10 Wyrick Susan D. Officer F-InKind D Common Stock 836 2.56 2.1K 157,395 D
2025-03-10 Harr Steve Director / Officer F-InKind D Common Stock 12,820 2.56 32.8K 7,876,930 D
2025-03-10 Cassidy Bernard J Officer F-InKind D Common Stock 2,833 2.56 7.3K 112,990 D
2025-03-07 Wyrick Susan D. Officer M-Exempt D Restricted Stock Units 3,250 0.00 9,750 D
2025-03-07 Harr Steve Director / Officer M-Exempt A Common Stock 50,000 0.00 7,889,750 D
2025-03-07 Cassidy Bernard J Officer M-Exempt D Restricted Stock Units 11,041 0.00 33,126 D
2025-03-06 Wyrick Susan D. Officer A-Award A Stock Option (Right to Buy) 187,500 2.55 478.1K 187,500 D
2025-03-06 Harr Steve Director / Officer A-Award A Stock Option (Right to Buy) 750,000 2.55 1.91M 750,000 D
2025-03-06 Cassidy Bernard J Officer A-Award A Stock Option (Right to Buy) 240,000 2.55 612.0K 240,000 D
2025-03-03 Wyrick Susan D. Officer F-InKind D Common Stock 490 2.56 1.3K 154,981 D
2025-03-02 Wyrick Susan D. Officer M-Exempt A Common Stock 1,525 0.00 155,471 D
2025-01-08 FMR LLC 10% Owner S-Sale D Common Stock 100,000 6.11 611.0K 4,732,423 I
2025-01-06 Bishop Hans Edgar Director A-Award A Common Stock 14,285 0.00 5,804,774 D
2025-01-02 Wyrick Susan D. Officer M-Exempt A Common Stock 5,000 0.00 155,512 D
2024-12-13 Wyrick Susan D. Officer A-Award A Stock Option (Right to Buy) 5,100 1.89 9.6K 5,100 D
2024-10-07 Bishop Hans Edgar Director A-Award A Common Stock 5,938 0.00 5,790,489 D
2024-10-04 Wyrick Susan D. Officer Stock Option (Right to buy) 65,000 7.80 507.0K 0 D
2024-09-25 Mulligan Richard Director S-Sale D Common Stock 150,000 3.89 583.2K 2,698,121 D
2024-09-24 Mulligan Richard Director S-Sale D Common Stock 150,000 4.08 612.6K 2,848,121 D
2024-07-05 Bishop Hans Edgar Director A-Award A Common Stock 4,911 0.00 5,784,551
2024-06-06 Yang Patrick Y Director A-Award A Stock Option (Right to Buy) 54,278 7.36 399.5K 54,278
2024-06-06 Wilderotter Mary Agnes Director A-Award A Stock Option (Right to Buy) 54,278 7.36 399.5K 54,278
2024-06-06 Seitz Michelle Director A-Award A Stock Option (Right to Buy) 54,278 7.36 399.5K 54,278
2024-06-06 REICIN ALISE Director A-Award A Stock Option (Right to Buy) 54,278 7.36 399.5K 54,278
2024-06-06 NELSEN ROBERT Director / 10% Owner A-Award A Stock Option (Right to Buy) 54,278 7.36 399.5K 54,278
2024-06-06 Mulligan Richard Director A-Award A Stock Option (Right to Buy) 54,278 7.36 399.5K 54,278
2024-06-06 Cole Douglas G. Director A-Award A Stock Option (Right to Buy) 54,278 7.36 399.5K 54,278
2024-06-06 Bishop Hans Edgar Director A-Award A Stock Option (Right to Buy) 54,278 7.36 399.5K 54,278
2024-06-06 Bilenker Joshua H. Director A-Award A Stock Option (Right to Buy) 65,000 7.36 478.4K 65,000
2024-04-05 Bishop Hans Edgar Director A-Award A Common Stock 2,774 0.00 5,779,640
2024-04-01 FMR LLC 10% Owner Common Stock 0 0.00 61 I
2024-03-08 Yang Patrick Y Director S-Sale D Common Stock 25,000 9.45 236.3K 149,250
2024-03-07 WILLIAMS DOUGLAS E Officer A-Award A Stock Option (Right to Buy) 301,875 9.58 2.89M 301,875
2024-03-07 Hordo Christian Officer A-Award A Restricted Stock Units 37,500 0.00 37,500
2024-03-07 Harr Steve Director / Officer A-Award A Restricted Stock Units 200,000 0.00 200,000
2024-03-07 Hardy Nathan Officer A-Award A Restricted Stock Units 67,083 0.00 67,083
2024-03-07 Cassidy Bernard J Officer A-Award A Restricted Stock Units 44,167 0.00 44,167
2024-02-12 Flagship Pioneering Inc. 10% Owner P-Purchase A Pre-Funded Warrants to purchase Common Stock 2,727,272 0.00 272.73 2,727,272
2024-02-12 Flagship Pioneering Fund VII General Partner LLC 10% Owner I Pre-Funded Warrants to purchase Common Stock 2,727,272 0.00 272.73 0
2024-02-08 NELSEN ROBERT Director / 10% Owner P-Purchase A Common Stock 363,637 5.50 2.00M 10,667,387
2024-02-08 CRANDELL KEITH 10% Owner P-Purchase A Common Stock 363,637 5.50 2.00M 10,667,387
2024-02-08 ARCH Venture Fund X, L.P. 10% Owner P-Purchase A Common Stock 727,272 5.50 4.00M 12,446,022
2024-01-05 Wilderotter Mary Agnes Director A-Award A Common Stock 1,470 0.00 7,106
2024-01-05 Bishop Hans Edgar Director A-Award A Common Stock 4,901 0.00 5,776,866
2023-12-15 Hordo Christian Officer S-Sale D Common Stock 75,000 4.00 300.1K 867,455
2023-11-02 WILLIAMS DOUGLAS E Officer A-Award A Restricted Stock Units 10,000 0.00 10,000
2023-11-02 Hordo Christian Officer A-Award A Restricted Stock Units 10,000 0.00 10,000
2023-11-02 Hardy Nathan Officer A-Award A Restricted Stock Units 10,000 0.00 10,000
2023-10-05 Wilderotter Mary Agnes Director A-Award A Common Stock 2,077 0.00 5,636
2023-10-05 Bishop Hans Edgar Director A-Award A Common Stock 6,925 0.00 5,771,965
2023-09-13 Flagship Pioneering Inc. 10% Owner J-Other D Common Stock 2,825,989 0.00 8,615,337
2023-07-05 Wilderotter Mary Agnes Director A-Award A Common Stock 1,245 0.00 3,559
2023-07-05 Bishop Hans Edgar Director A-Award A Common Stock 4,152 0.00 5,765,040
2023-06-08 Yang Patrick Y Director A-Award A Stock Option (Right to Buy) 65,000 6.70 435.5K 65,000
2023-06-08 Wilderotter Mary Agnes Director A-Award A Stock Option (Right to Buy) 65,000 6.70 435.5K 65,000
2023-06-08 Seitz Michelle Director A-Award A Stock Option (Right to Buy) 65,000 6.70 435.5K 65,000
2023-06-08 REICIN ALISE Director A-Award A Stock Option (Right to Buy) 65,000 6.70 435.5K 65,000
2023-06-08 NELSEN ROBERT Director / 10% Owner A-Award A Stock Option (Right to Buy) 65,000 6.70 435.5K 65,000
2023-06-08 Cole Douglas G. Director A-Award A Stock Option (Right to Buy) 65,000 6.70 435.5K 65,000
2023-06-08 Bishop Hans Edgar Director A-Award A Stock Option (Right to Buy) 65,000 6.70 435.5K 65,000
2023-06-08 Bilenker Joshua H. Director A-Award A Stock Option (Right to Buy) 65,000 6.70 435.5K 65,000
2023-06-07 Flagship Ventures Fund V General Partner LLC 10% Owner S-Sale D Common Stock 177,240 6.24 1.11M 10,743,293
2023-06-06 Flagship Ventures Fund V General Partner LLC 10% Owner S-Sale D Common Stock 181,461 6.31 1.14M 10,920,533
2023-05-26 Flagship Ventures Fund V General Partner LLC 10% Owner S-Sale D Common Stock 9,330 6.23 58.1K 1,425,334
2023-05-25 Flagship Ventures Fund V General Partner LLC 10% Owner S-Sale D Common Stock 13,127 6.35 83.4K 1,434,664
2023-05-24 Flagship Ventures Fund V General Partner LLC 10% Owner S-Sale D Common Stock 308,290 6.57 2.02M 11,276,909
2023-04-10 WILLIAMS DOUGLAS E Officer A-Award A Stock Option (Right to Buy) 1,100,000 3.28 3.61M 1,100,000
2023-04-05 Wilderotter Mary Agnes Director A-Award A Common Stock 2,314 0.00 2,314
2023-04-05 Bishop Hans Edgar Director A-Award A Common Stock 7,716 0.00 5,760,888
2023-03-02 Mulligan Richard Director / Officer A-Award A Stock Options (Right to Buy) 200,000 3.76 752.0K 200,000
2023-03-02 Hordo Christian Officer A-Award A Stock Options (Right to Buy) 185,000 3.76 695.6K 185,000
2023-03-02 Harr Steve Director / Officer A-Award A Stock Options (Right to Buy) 650,000 3.76 2.44M 650,000
2023-03-02 Hardy Nathan Officer A-Award A Stock Options (Right to Buy) 200,000 3.76 752.0K 200,000
2023-03-02 Cassidy Bernard J Officer A-Award A Stock Options (Right to Buy) 140,000 3.76 526.4K 140,000
2023-01-05 NELSEN ROBERT Director A-Award A Common Stock 536 0.00 1,353
2023-01-05 Bishop Hans Edgar Director A-Award A Common Stock 6,702 0.00 5,753,172
2022-10-05 NELSEN ROBERT Director A-Award A Common Stock 321 0.00 817
2022-10-05 Bishop Hans Edgar Director A-Award A Common Stock 4,012 0.00 5,746,470
2022-07-05 NELSEN ROBERT Director A-Award A Common Stock 266 0.00 496
2022-07-05 Bishop Hans Edgar Director A-Award A Common Stock 3,328 0.00 5,742,458
2022-06-13 MacDonald James J. Director M-Exempt A Common Stock 66,796 1.48 98.9K 497,396
2022-06-06 Yang Patrick Y Director A-Award A Stock Option (Right to Buy) 65,000 0.00 65,000
2022-06-06 Wilderotter Mary Agnes Director A-Award A Stock Option (Right to Buy) 65,000 0.00 65,000
2022-06-06 Seitz Michelle Director A-Award A Stock Option (Right to Buy) 65,000 0.00 65,000
2022-06-06 REICIN ALISE Director A-Award A Stock Option (Right to Buy) 65,000 0.00 65,000
2022-06-06 NELSEN ROBERT Director A-Award A Stock Option (Right to Buy) 65,000 0.00 65,000
2022-06-06 Cole Douglas G. Director A-Award A Stock Option (Right to Buy) 65,000 4.95 321.8K 65,000
2022-06-06 Bishop Hans Edgar Director A-Award A Stock Option (Right to Buy) 65,000 0.00 65,000
2022-06-06 Bilenker Joshua H. Director A-Award A Stock Option (Right to Buy) 65,000 0.00 65,000
2022-04-05 NELSEN ROBERT Director A-Award A Common Stock 230 0.00 230
2022-04-05 Bishop Hans Edgar Director A-Award A Common Stock 2,880 0.00 5,739,130
2022-03-21 Yang Patrick Y Director P-Purchase A Common Stock 28,000 7.30 204.4K 174,250
2022-03-03 Mulligan Richard Director / Officer A-Award A Stock Options (Right to Buy) 250,000 5.70 1.43M 250,000
2022-03-03 MacDonald James J. Director A-Award A Stock Options (Right to Buy) 225,000 0.00 225,000
2022-03-03 Hordo Christian Director / Officer A-Award A Stock Options (Right to Buy) 225,000 0.00 225,000
2022-03-03 Harr Steve Director / Officer A-Award A Stock Options (Right to Buy) 760,000 5.70 4.33M 760,000
2022-03-03 Hardy Nathan Director / Officer A-Award A Stock Options (Right to Buy) 225,000 0.00 225,000
2022-03-03 AGARWAL SUNIL Officer A-Award A Stock Options (Right to Buy) 250,000 5.70 1.43M 250,000
2022-02-18 MacDonald James J. Officer S-Sale D Common Stock 333 6.28 2.1K 429,417
2021-11-15 MacDonald James J. Officer A-Award A Common Stock 1,000 18.23 18.2K 429,750
2021-09-16 AGARWAL SUNIL Officer S-Sale D Common Stock 1,627 26.00 42.3K 1,550,000
2021-09-15 AGARWAL SUNIL Officer S-Sale D Common Stock 58,373 26.07 1.52M 1,551,627
2021-09-10 Hordo Christian Officer S-Sale D Common Stock 1,477 25.00 36.9K 942,455
2021-09-09 Hordo Christian Officer M-Exempt A Common Stock 39,205 1.48 58.0K 1,008,603
2021-09-03 Hordo Christian Officer M-Exempt D Stock Option (Right to Buy) 700 1.48 1.0K 128,008
2021-09-02 Hordo Christian Officer M-Exempt A Common Stock 6,558 1.48 9.7K 977,356
2021-09-01 Hordo Christian Officer S-Sale D Common Stock 1,134 25.00 28.4K 973,800
2021-08-30 Hordo Christian Officer S-Sale D Common Stock 1,100 25.01 27.5K 975,000
2021-04-21 NELSEN ROBERT Director / 10% Owner J-Other A Common Stock 12,500 0.00 12,500
2021-04-14 Harr Steve Director / Officer G-Gift D Common Stock 167,000 0.00 7,839,750
2021-02-08 von Maltzahn Geoffrey Director C-Conversion A Common Stock 1,464,488 0.00 1,464,488
2021-02-08 NELSEN ROBERT Director C-Conversion D Series B Convertible Preferred Stock 2,343,750 0.00 0
2021-02-08 MacDonald James J. Officer C-Conversion D Series A-1 Convertible Preferred Stock 93,750 0.00 0
2021-02-08 Harr Steve Director / Officer C-Conversion A Common Stock 2,031,250 0.00 8,173,750
2021-02-08 Flagship Ventures Fund V General Partner LLC 10% Owner C-Conversion A Common Stock 11,441,326 0.00 11,441,326
2021-02-08 Bishop Hans Edgar Director C-Conversion D Series A-2 Convertible Preferred Stock 800,000 0.00 0
2021-02-08 ARCH Venture Fund X, L.P. 10% Owner C-Conversion D Series A-1 Convertible Preferred Stock 3,687,500 0.00 0 I
2021-02-03 von Maltzahn Geoffrey Director D Series A-2 Convertible Preferred Stock 1,464,488 0.00 0
2021-02-03 Yang Patrick Y Director D Common Stock 0 0.00 146,250
2021-02-03 Wilderotter Mary Agnes Director A-Award A Stock Option (Right to Buy) 23,591 25.00 589.8K 23,591
2021-02-03 Seitz Michelle Director D Stock Option (Right to Buy) 93,750 7.80 731.3K 0
2021-02-03 REICIN ALISE Director D Stock Option (Right to Buy) 93,750 7.80 731.3K 0
2021-02-03 NELSEN ROBERT Director A-Award A Stock Option (Right to Buy) 14,000 25.00 350.0K 14,000
2021-02-03 Mulligan Richard Director / Officer D Common Stock 0 0.00 2,998,121
2021-02-03 MacDonald James J. Officer D Stock Option (Right to Buy) 118,750 1.48 175.8K 0
2021-02-03 Hordo Christian Officer D Common Stock 0 0.00 975,000
2021-02-03 Harr Steve Director / Officer D Series B Convertible Preferred Stock 156,250 0.00 0
2021-02-03 Hardy Nathan Officer D Stock Option (Right to Buy) 118,750 1.48 175.8K 0
2021-02-03 Flagship Ventures Fund V General Partner LLC 10% Owner I Series A-2 Convertible Preferred Stock 11,585,199 0.00 0
2021-02-03 Cole Douglas G. Director 0 0.00 0
2021-02-03 Bishop Hans Edgar Director D Series B Convertible Preferred Stock 156,250 0.00 0
2021-02-03 Bilenker Joshua H. Director A-Award A Stock Option (Right to Buy) 11,795 25.00 294.9K 11,795
2021-02-03 ARCH Venture Fund X, L.P. 10% Owner I Series B Convertible Preferred Stock 2,343,750 0.00 0
2021-02-03 AGARWAL SUNIL Officer A-Award A Stock Option (Right to Buy) 48,000 25.00 1.20M 48,000

Executive team

Top executives
Shares Outstanding
278.29M

Executive compensation

Executive compensation (annual)
# Year Executive Salary Bonus Stock award Option award Incentive Other Total % Stock-
based
Filing
1 2025 President, Chief Executive Officer, and Director 696.1K 425.0K 1.33M 450.4K 4.0K 2.90M 60.37%
2 2025 Former Executive Vice President, General Counsel, and Corporate Secretary 404.0K 136.0K 424.8K 51.3K 1.02M 55.19%
3 2024 President, Chief Executive Officer, and Director 681.0K 1.92M 5.86M 328.6K 4.0K 8.79M 88.47%
4 2024 Steven D. Harr, M.D. President, Chief Executive Officer, and Director 681.0K 1.92M 5.86M 328.6K 4.0K 8.79M 88.47%
5 2024 Nathan Hardy Former Executive Vice President, Chief Financial Officer 390.3K 642.7K 1.97M 52.1K 3.05M 85.50%
6 2024 Douglas E. Williams, Ph.D. Former Executive Vice President and President, Research and Development 190.8K 436.7K 1.97M 161.3K 2.75M 87.21%
7 2024 Bernard J. Cassidy Executive Vice President, General Counsel, and Corporate Secretary 472.6K 423.1K 1.29M 152.0K 4.0K 2.35M 73.20%
8 2024 Former Executive Vice President, General Counsel, and Corporate Secretary 472.6K 423.1K 1.29M 152.0K 4.0K 2.35M 73.20%
9 2023 Douglas E. Williams, Ph.D. Former Executive Vice President and President, Research and Development 412.7K 30.8K 2.38M 220.4K 4.0K 3.04M 79.08%
10 2023 Steven D. Harr, M.D. President, Chief Executive Officer, and Director 659.4K 1.63M 377.0K 4.0K 2.67M 61.06%
11 2023 Nathan Hardy Executive Vice President, Chief Financial Officer 468.9K 30.8K 501.9K 180.1K 4.0K 1.19M 44.93%
12 2023 Nathan Hardy Former Executive Vice President, Chief Financial Officer 468.9K 30.8K 501.9K 180.1K 4.0K 1.19M 44.93%
13 2023 Bernard J. Cassidy Executive Vice President, General Counsel, and Corporate Secretary 457.6K 351.3K 174.4K 4.0K 987.4K 35.58%
14 2022 Bernard J. Cassidy Executive Vice President, General Counsel, and Corporate Secretary 129.8K 3.77M 54.7K 4.0K 3.95M 95.23%
15 2022 Steven D. Harr, M.D. President, Chief Executive Officer, and Director 644.8K 2.77M 389.1K 4.0K 3.81M 72.74%
16 2022 Sunil Agarwal, M.D. Former Executive Vice President, Head of Development, and Chief Medical Officer 530.9K 911.2K 213.5K 4.0K 1.66M 54.91%
17 2021 Sunil Agarwal, M.D. Former Executive Vice President, Head of Development, and Chief Medical Officer 512.6K 10.0K 1.20M 205.8K 1.93M 62.23%
18 2021 Sunil Agarwal, M.D. Chief Medical Officer Executive Vice President, 512.6K 10.0K 1.20M 205.8K 1.93M 62.23%
19 2021 Steven D. Harr, M.D. President, Chief Executive Officer, and Director 611.2K 200.0K 375.0K 1.19M 0.00%
20 2021 Steven D. Harr, M.D. President, Chief Executive Officer, and Director Executive Vice President, Head of Development, and 611.2K 200.0K 375.0K 1.19M 0.00%
21 2021 Nathan Hardy Chief Financial Officer 413.5K 100.0K 170.0K 683.5K 0.00%
22 2020 Steven D. Harr, M.D. President, Chief Executive Officer, and Director Executive Vice President, Head of Development, and 535.0K 6.02M 294.3K 6.85M 87.89%
CEO compensation breakdown

Proxy statements

Proxy statements (DEF 14A)
Filing date Form type Filing
2026-04-24 DEFA14A
2026-04-24 DEF 14A
2025-04-25 DEFA14A
2025-04-25 DEF 14A

Recent SEC filings

Recent SEC filings
Filing date Form type Filing
2026-05-21 SC 13G
2026-05-15 8-K
2026-05-11 S-8
2026-05-11 8-K
2026-05-11 10-Q
2026-04-24 DEFA14A
2026-04-24 DEF 14A
2026-04-24 ARS
2026-04-24 8-K
2026-04-13 8-K

Executive team

NameTitleCompensationGender
Steven D. Harr President, Chief Executive Officer & Director 1M
Brian D. Piper Executive Vice President & Chief Financial Officer 653.0K male
Dhavalkumar D. Patel Executive Vice President & Chief Scientific Officer
Gary Meininger Chief Medical Officer
John Gerecitano Head of Oncology Research & Development male
Snehal Patel Senior Vice President & Chief Technical Officer male
Susan Wyrick Treasurer, Principal Accounting Officer and Senior VP of Finance & Accounting female
Aaron Grossman Executive VP, Chief Legal Officer & Corporate Secretary male
Yuko Soneoka Head of Intellectual Property
Debra Wisdom VP & Head of People female
ESG Rating
B
BIOTECHNOLOGY
Rank: 177 out of 714
2026
E (Environmental)
61.1 / 56.3
Company / Sector avg.
S (Social)
67.7 / 62.4
Company / Sector avg.
G (Governance)
60.9 / 60.9
Company / Sector avg.
ESG Total
63.2 / 59.9
Company / Sector avg.
ESG Score History BIOTECHNOLOGY
Benchmark vs Sector
Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend history

Earnings history

Earnings reports

Stock splits