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Palvella Therapeutics, Inc. (PVLA)

USD152.21 +2.53 (+1.69%)
US NASDAQ Healthcare Biotechnology
Address 125 Strafford Avenue 19087
Wayne, PA, US
CEO Wesley H. Kaupinen
IPO 2015-01-02
CIK 1583648 ISIN US6979471090

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Description

Palvella Therapeutics, Inc. is a clinical-stage biopharmaceutical company dedicated to the discovery, development, and commercialization of innovative treatments for patients afflicted with severe and uncommon inherited skin conditions. Central to its pipeline is QTORIN 3.9% rapamycin anhydrous gel (referred to as QTORIN rapamycin), which is currently undergoing Phase 3 clinical trials for microcystic lymphatic malformations. Additionally, this drug is in Phase 2 evaluation for treating cutaneous venous malformations. Beyond these specific indications, Palvella is also advancing QTORIN rapamycin for the treatment of other dermatological diseases driven by the mTOR pathway. The company's headquarters are situated in Wayne, Pennsylvania.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
USD152.21 +2.53 (+1.69%)
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Volume Profile
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Liquidity & share structure
Average Volume
263.1K
Beta
-0.19
Float Shares
7.39M
Free Float %
62.5%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
+3.03% -2.53% -1.05% +53.37% +54.27% +20.18% +506.22% +639.94% +639.94% +639.94% +639.94%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
vs.
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Analyst Consensus (10 ratings, all time) Buy
Price Targets & DCF
Current price
152.21
Low 143.00 -6.1%
Consensus 205.15 +34.8%
Median 205.00 +34.7%
High 255.00 +67.5%
DCF (Unlevered) 4.71 -96.9%
DCF (Levered) 5.10 -96.7%

DCF figures are point estimates: small changes in growth or discount-rate assumptions move them materially. Read them as a reference, not a precise target.

Ratings Trend (MoM) 100% Bullish
Rating 2026-05 Change
Strong Buy 0 0
Buy 15 0
Hold 0 0
Sell 0 0
Strong Sell 0 0
Price Target Summary
Period # Analysts Avg Target
Last Month
Last Quarter 4
231.25
+51.9%
Last Year 29
158.17
+3.9%
All Time 31
150.39
-1.2%
Quality scores
Altman Z-Score
27.38
Safe zone
Piotroski F-Score
2 / 9
Weak
MOAT Score
1 / 10
No MOAT
Composite Rating
C-
Overall Score
1 / 5
Low
DCF Score
2 / 5
Medium
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
3 / 5
Medium
P/E Score
1 / 5
Low
P/Book Score
1 / 5
Low
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
  • EPS growth Biotechnology: +29.7%
    +52.6% Q1'26: +67.4% (vs Q1'25)
  • FCF margin FCF growth · Biotechnology: +16.2%
  • EBIT margin Biotechnology: +0.0%
  • ROIC Biotechnology: -16.1%
    Q1'26: +205.2% (vs Q1'25)
  • Share dilution Biotechnology: -3.4%
    +405.5% Q1'26: +487.8% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    -0.02× Q1'26: -0.01× (vs Q1'25)
Valuation Multiples From To
Price Forecast (3Y) From To
Model
Adjust
P/E
Theoretical Return — If Invested Today

* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.

DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (-0.12) × ERP
WACC = 100% × Ke + 0% × Kd (919.1%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Intrinsic value (base): 4.71 Current price: 152.21
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2016
actual
Dec 2017
actual
Dec 2018
actual
Dec 2019
actual
Dec 2020
actual
Dec 2021
actual
Dec 2022
actual
Dec 2023
actual
Dec 2024
actual
Dec 2025
actual
Dec 2026
9 Rev. Ana.
12 EPS Ana.
Dec 2027
11 Rev. Ana.
9 EPS Ana.
Dec 2028
10 Rev. Ana.
9 EPS Ana.
Dec 2029
5 Rev. Ana.
3 EPS Ana.
Dec 2030
5 Rev. Ana.
3 EPS Ana.
Revenue
3.87M
est.
13.89M
est.
30.08M
est.
33.82M
est.
31.25M
est.
31.42M
est: 31.41M (+0.0%)
25.90M
est: 26.57M (-2.5%)
est: 31.98M (-100.0%)
est: 25.4K (-100.0%)
26.7K
11.8K – 57.4K
31.51M
16.18M – 65.71M
+118,045.6% YoY
140.60M
139.39M – 141.82M
+346.3% YoY
337.02M
149.04M – 725.22M
+139.7% YoY
706.35M
312.37M – 1.52B
+109.6% YoY
EBITDA
773.7K
est.
2.78M
est.
6.02M
est.
6.76M
est.
6.25M
est.
-43.37M
est: 6.28M (-790.4%)
-30.50M
est: 5.31M (-674.0%)
18.69M
est: 6.40M (+192.2%)
-13.12M
est: 5.1K (-258,614.0%)
-35.90M
5.3K
2.4K – 11.5K
6.30M
3.24M – 13.14M
+118,054.5% YoY
28.12M
27.88M – 28.36M
+346.3% YoY
67.40M
29.81M – 145.04M
+139.7% YoY
141.27M
62.47M – 303.99M
+109.6% YoY
EBIT
773.7K
est.
2.78M
est.
6.02M
est.
6.76M
est.
6.25M
est.
-45.74M
est: 6.28M (-828.1%)
-33.28M
est: 5.31M (-726.3%)
18.69M
est: 6.40M (+192.2%)
-13.12M
est: 5.1K (-258,614.0%)
-35.90M
5.3K
2.4K – 11.5K
6.30M
3.24M – 13.14M
+118,054.5% YoY
28.12M
27.88M – 28.36M
+346.3% YoY
67.40M
29.81M – 145.04M
+139.7% YoY
141.27M
62.47M – 303.99M
+109.6% YoY
Net Income
-95.57M
est.
-114.42M
est.
-85.03M
est.
-135.34M
est.
-117.53M
est.
-45.74M
est: -125.55M (+63.6%)
-33.28M
est: -112.96M (+70.5%)
18.69M
est: -62.33M (+130.0%)
-17.43M
est: -31.93M (+45.4%)
-41.72M
est: -37.19M (-12.2%)
-75.63M
-80.59M – -40.42M
-103.4% YoY
-109.74M
-118.02M – -48.04M
-45.1% YoY
-49.45M
-103.00M – 92.59M
+54.9% YoY
58.99M
16.22M – 147.31M
+219.3% YoY
225.01M
61.86M – 561.95M
+281.5% YoY
SGA
3.22M
est.
11.56M
est.
25.04M
est.
28.16M
est.
26.02M
est.
16.68M
est: 26.15M (-36.2%)
16.38M
est: 22.12M (-25.9%)
3.08M
est: 26.63M (-88.4%)
5.94M
est: 21.1K (+28,030.6%)
15.76M
22.2K
9.8K – 47.8K
26.24M
13.47M – 54.72M
+118,050.9% YoY
117.08M
116.07M – 118.09M
+346.3% YoY
280.64M
124.11M – 603.90M
+139.7% YoY
588.18M
260.11M – 1.27B
+109.6% YoY
EPS
-42.93
est.
-51.40
est.
-38.20
est.
-60.80
est.
-52.80
est.
-56.69
est: -56.40 (-0.5%)
-29.61
est: -50.74 (+41.6%)
14.74
est: -28.00 (+152.6%)
-7.83
est: -2.84 (-175.5%)
-3.71
est: -3.52 (-5.5%)
-5.55
-7.16 – -3.59
-57.7% YoY
-6.52
-10.49 – -4.27
-17.4% YoY
-2.58
-9.15 – 8.23
+60.4% YoY
5.24
1.44 – 13.09
+303.3% YoY
20.00
5.50 – 49.95
+281.5% YoY
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-12 C 2/5 2/5 1/5 1/5 4/5 1/5 1/5
2026-05-11 C 2/5 2/5 1/5 1/5 4/5 1/5 1/5
2026-05-08 C 2/5 2/5 1/5 1/5 4/5 1/5 1/5
2026-05-07 C 2/5 2/5 1/5 1/5 4/5 1/5 1/5
2026-05-06 C- 1/5 2/5 1/5 1/5 3/5 1/5 1/5
2026-05-05 C- 1/5 2/5 1/5 1/5 3/5 1/5 1/5
2026-05-04 C- 1/5 2/5 1/5 1/5 3/5 1/5 1/5
2026-05-01 C- 1/5 2/5 1/5 1/5 3/5 1/5 1/5
2026-04-30 C- 1/5 2/5 1/5 1/5 3/5 1/5 1/5
2026-04-29 C- 1/5 2/5 1/5 1/5 3/5 1/5 1/5
2026-04-28 C- 1/5 2/5 1/5 1/5 3/5 1/5 1/5
2026-04-27 C- 1/5 2/5 1/5 1/5 3/5 1/5 1/5
2026-04-24 C- 1/5 3/5 1/5 1/5 2/5 1/5 1/5
2026-04-23 C- 1/5 3/5 1/5 1/5 2/5 1/5 1/5
2026-04-22 C- 1/5 3/5 1/5 1/5 2/5 1/5 1/5
2026-04-21 C- 1/5 3/5 1/5 1/5 2/5 1/5 1/5
2026-04-20 C- 1/5 3/5 1/5 1/5 2/5 1/5 1/5
2026-04-17 C- 1/5 3/5 1/5 1/5 2/5 1/5 1/5
2026-04-16 C- 1/5 3/5 1/5 1/5 2/5 1/5 1/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
-25.01M
OE per share TTM
-4.68
Owner's Yield
-1.71%
Maintenance CapEx ratio
Maint CapEx / Avg PPE
41.2%

Ownership Overview

Ownership breakdown
At a glance
Institutional holders
26
Total invested
29.50M
Insider transactions (90d)
0
Beneficial owners (>5%)
16
Beneficial owners (>5%)
# Reporting person Amount owned % of class Sole voting Shared voting Sole dispositive Shared dispositive Type Citizenship Filing date SEC filing
1 Checkpoint Capital (Master) Fund, LP 4.94M 6.00% 4.94M PN Delaware 2023-06-12
2 Checkpoint Capital, LP 4.94M 6.00% 4.94M IA, HC Delaware 2023-06-12
3 Sam Huang 4.94M 6.00% 4.94M HC, IN Delaware 2023-06-12
4 BVF Inc. 257.6K 19.50% 257.6K CO Delaware 2024-05-17
5 BVF Partners L.P. 257.6K 19.50% 257.6K IA, PN Delaware 2024-05-17
6 Mark N. Lampert 257.6K 19.50% 257.6K IN Delaware 2024-05-17
7 BVF GP Holdings LLC 244.9K 18.50% 244.9K OO Delaware 2024-05-17
8 ADAR1 Capital Management GP, LLC 138.6K 10.50% 138.6K 138.6K OO Texas 2024-08-01
9 ADAR1 Capital Management, LLC 138.6K 10.50% 138.6K 138.6K IA Texas 2024-08-01
10 Daniel Schneeberger 138.6K 10.50% 138.6K 138.6K IN Texas 2024-08-01
11 BVF I GP LLC 137.6K 10.40% 137.6K OO Delaware 2024-05-17
12 Biotechnology Value Fund, L.P. 137.6K 10.40% 137.6K PN Delaware 2024-05-17
13 BVF II GP LLC 107.3K 8.10% 107.3K OO Delaware 2024-05-17
14 Biotechnology Value Fund II, L.P. 107.3K 8.10% 107.3K PN Delaware 2024-05-17
15 BVF Partners OS Ltd. 9.3K 1.00% 9.3K CO Delaware 2024-05-17
16 Biotechnology Value Trading Fund OS LP 9.3K 1.00% 9.3K PN Delaware 2024-05-17

Institutional Activity (13F)

Institutional ownership trend From To
13F snapshot — 2026 Q1
Investors holding
26
-121 vs prev Q
New positions
7
Closed positions
126
Increased
14
Reduced
6
Put/Call ratio
0.00
Calls held
Puts held
Top institutional holders
# Investor Shares / Δ Mkt value / Δ Own% / Δ Weight% / Δ Avg px / Perf. Hold / Status
1 82.7K +82.7K (+100.0%) 8.65B +8.7B (+100.0%) 0.75% +0.747 pp 5.08% +5.076 pp USD104.67 +0.0% 1 qtrs NEW
2 SUVRETTA CAPITAL MANAGEMENT, LLC 892.4K +70.0K (+8.5%) 93.41M +41.9M (+81.2%) 8.07% +0.625 pp 1.91% +0.594 pp USD25.40 +312.1% 5 qtrs
3 BVF INC/IL 879.0K -282.2K (-24.3%) 92.01M +19.2M (+26.4%) 7.94% -2.562 pp 3.10% +0.146 pp USD32.28 +224.3% 5 qtrs
4 FRAZIER LIFE SCIENCES MANAGEMENT, L.P. 722.4K +— (+0.0%) 75.61M +30.3M (+67.0%) 6.53% -0.007 pp 2.03% +0.674 pp USD13.27 +688.8% 5 qtrs
5 FIRST LIGHT ASSET MANAGEMENT, LLC 709.1K +167.6K (+30.9%) 74.23M +40.3M (+118.6%) 6.41% +1.510 pp 5.67% +2.475 pp USD72.61 +44.2% 2 qtrs
6 VANGUARD GROUP INC 560.6K +66.0K (+13.3%) 58.68M +27.7M (+89.2%) 5.07% +0.592 pp 0.00% +0.000 pp USD56.92 +83.9% 5 qtrs
7 BLACKROCK, INC. 559.1K +71.4K (+14.7%) 58.52M +27.9M (+91.4%) 5.05% +0.641 pp 0.00% +0.001 pp USD36.80 +184.4% 5 qtrs
8 STATE STREET CORP 420.5K +283.2K (+206.3%) 44.01M +35.4M (+411.5%) 3.80% +2.558 pp 0.00% +0.001 pp USD83.29 +25.7% 4 qtrs
9 SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC 389.4K +354.5K (+1,016.0%) 40.76M +38.6M (+1,763.3%) 3.52% +3.204 pp 0.85% +0.802 pp USD100.91 +3.7% 2 qtrs
10 JENNISON ASSOCIATES LLC 387.5K +280.6K (+262.4%) 40.56M +33.9M (+505.1%) 3.50% +2.535 pp 0.02% +0.020 pp USD93.09 +12.4% 2 qtrs
11 FEDERATED HERMES, INC. 368.0K +29.0K (+8.6%) 38.52M +17.3M (+81.2%) 3.33% +0.259 pp 0.06% +0.027 pp USD66.00 +58.6% 2 qtrs
12 WOODLINE PARTNERS LP 300.5K -45.2K (-13.1%) 31.46M +9.8M (+45.1%) 2.72% -0.412 pp 0.12% +0.020 pp USD24.91 +320.2% 4 qtrs
13 ALLIANCEBERNSTEIN L.P. 269.0K +269.0K (+100.0%) 28.16M +28.2M (+100.0%) 2.43% +2.432 pp 0.01% +0.009 pp USD104.67 +0.0% 1 qtrs NEW
14 PERCEPTIVE ADVISORS LLC 266.3K -128.8K (-32.6%) 27.87M +3.1M (+12.5%) 2.41% -1.168 pp 0.50% -0.218 pp USD62.69 +67.0% 2 qtrs
15 FMR LLC 231.8K +121.3K (+109.8%) 24.26M +17.3M (+250.4%) 2.09% +1.095 pp 0.00% +0.001 pp USD84.65 +23.7% 3 qtrs
16 MORGAN STANLEY 220.7K +82.2K (+59.3%) 23.10M +14.4M (+166.0%) 1.99% +0.741 pp 0.00% +0.001 pp USD53.86 +94.3% 5 qtrs
17 ARTISAN PARTNERS LIMITED PARTNERSHIP 211.6K +211.6K (+100.0%) 22.14M +22.1M (+100.0%) 1.91% +1.912 pp 0.03% +0.033 pp USD104.67 +0.0% 1 qtrs NEW
18 BIOIMPACT CAPITAL LLC 205.7K +138.3K (+205.2%) 21.54M +17.3M (+409.5%) 1.86% +1.250 pp 2.46% +1.772 pp USD90.91 +15.1% 2 qtrs
19 GEODE CAPITAL MANAGEMENT, LLC 179.0K +10.9K (+6.5%) 18.74M +8.2M (+77.8%) 1.62% +0.097 pp 0.00% +0.001 pp USD29.07 +260.1% 5 qtrs
20 FRED ALGER MANAGEMENT, LLC 150.0K -36.7K (-19.7%) 15.70M +4.0M (+34.1%) 1.36% -0.334 pp 0.06% +0.016 pp USD59.78 +75.1% 3 qtrs
21 BALYASNY ASSET MANAGEMENT L.P. 108.9K -57.7K (-34.6%) 11.40M +956.4K (+9.2%) 0.98% -0.523 pp 0.01% +0.001 pp USD62.69 +67.0% 4 qtrs
22 SAMSARA BIOCAPITAL, LLC 104.8K -104.8K (-50.0%) 10.97M -2.2M (-16.5%) 0.95% -0.949 pp 1.13% -0.584 pp USD12.00 +772.3% 5 qtrs
23 EVENTIDE ASSET MANAGEMENT, LLC 101.7K +101.7K (+100.0%) 10.65M +10.6M (+100.0%) 0.92% +0.920 pp 0.17% +0.166 pp USD104.67 +0.0% 1 qtrs NEW
24 GOLDMAN SACHS GROUP INC 98.9K -137.7K (-58.2%) 10.36M -4.5M (-30.2%) 0.89% -1.247 pp 0.00% -0.001 pp USD48.65 +115.1% 4 qtrs
25 CAPTION MANAGEMENT, LLC 95.3K +95.3K (+100.0%) 9.98M +10.0M (+100.0%) 0.86% +0.861 pp 0.07% +0.068 pp USD104.67 +0.0% 1 qtrs NEW
26 CLIO ASSET MANAGEMENT LLC 91.6K +1.0 (+0.0%) 9.59M +3.8M (+67.0%) 0.83% -0.001 pp 7.45% +3.185 pp USD22.60 +363.1% 3 qtrs
27 POINT72 ASSET MANAGEMENT, L.P. 77.3K -240.0K (-75.6%) 8.09M -11.8M (-59.3%) 0.70% -2.172 pp 0.01% -0.024 pp USD62.69 +67.0% 2 qtrs
28 SIREN, L.L.C. 75.0K +75.0K (+100.0%) 7.85M +7.9M (+100.0%) 0.68% +0.678 pp 0.23% +0.234 pp USD104.67 +0.0% 1 qtrs NEW
29 AWM INVESTMENT COMPANY, INC. 69.4K +— (+0.0%) 7.27M +2.9M (+67.0%) 0.63% -0.001 pp 0.70% +0.294 pp USD27.99 +274.0% 4 qtrs
30 CLEARBRIDGE INVESTMENTS, LLC 60.6K +60.6K (+100.0%) 6.35M +6.3M (+100.0%) 0.55% +0.548 pp 0.01% +0.005 pp USD104.67 +0.0% 1 qtrs NEW
31 ARTIA GLOBAL PARTNERS LP 59.2K +59.2K (+100.0%) 6.20M +6.2M (+100.0%) 0.54% +0.535 pp 0.99% +0.988 pp USD104.67 +0.0% 1 qtrs NEW
32 NORTHERN TRUST CORP 54.5K +487.0 (+0.9%) 5.70M +2.3M (+68.5%) 0.49% +0.004 pp 0.00% +0.000 pp USD24.92 +320.0% 4 qtrs
33 INVESCO LTD. 54.3K +5.7K (+11.6%) 5.68M +2.6M (+86.4%) 0.49% +0.051 pp 0.00% +0.000 pp USD67.07 +56.1% 2 qtrs
34 UBS ASSET MANAGEMENT AMERICAS INC 47.7K +47.7K (+100.0%) 4.99M +5.0M (+100.0%) 0.43% +0.431 pp 0.00% +0.001 pp USD104.67 +0.0% 1 qtrs NEW
35 NEUBERGER BERMAN GROUP LLC 44.9K +44.9K (+100.0%) 4.70M +4.7M (+100.0%) 0.41% +0.406 pp 0.00% +0.004 pp USD104.67 +0.0% 1 qtrs NEW
36 LISANTI CAPITAL GROWTH, LLC 41.5K +41.5K (+100.0%) 4.34M +4.3M (+100.0%) 0.37% +0.375 pp 1.03% +1.028 pp USD104.67 +0.0% 1 qtrs NEW
37 BLUE OWL CAPITAL HOLDINGS LP 40.3K -55.0K (-57.7%) 4.21M -1.8M (-29.4%) 0.36% -0.498 pp 0.32% -1.539 pp USD12.00 +772.3% 5 qtrs
38 SUSQUEHANNA INTERNATIONAL GROUP, LLP 38.2K +22.5K (+143.3%) 4.00M +3.0M (+306.2%) 0.35% +0.203 pp 0.00% +0.000 pp USD77.01 +35.9% 3 qtrs
39 UBS GROUP AG 36.5K +16.1K (+78.6%) 3.82M +2.5M (+198.2%) 0.33% +0.145 pp 0.00% +0.000 pp USD59.35 +76.4% 5 qtrs
40 BANK OF AMERICA CORP /DE/ 30.3K +25.6K (+545.6%) 3.17M +2.9M (+977.9%) 0.27% +0.231 pp 0.00% +0.000 pp USD93.38 +12.1% 5 qtrs
41 ROYCE & ASSOCIATES LP 30.0K -19.5K (-39.4%) 3.14M +37.4K (+1.2%) 0.27% -0.177 pp 0.03% +0.001 pp USD27.77 +276.9% 4 qtrs
42 SUPERSTRING CAPITAL MANAGEMENT LP 25.5K +25.5K (+100.0%) 2.67M +2.7M (+100.0%) 0.23% +0.230 pp 1.43% +1.427 pp USD104.67 +0.0% 1 qtrs NEW
43 BARCLAYS PLC 25.1K +15.4K (+157.1%) 2.63M +2.0M (+329.3%) 0.23% +0.139 pp 0.00% +0.001 pp USD72.71 +44.0% 5 qtrs
44 JANE STREET GROUP, LLC 24.0K +24.0K (+100.0%) 2.51M +2.5M (+100.0%) 0.22% +0.217 pp 0.00% +0.000 pp USD104.67 +0.0% 1 qtrs NEW
45 RENAISSANCE TECHNOLOGIES LLC 22.5K -67.2K (-74.9%) 2.36M -3.3M (-58.1%) 0.20% -0.608 pp 0.00% -0.004 pp USD30.97 +238.0% 5 qtrs
46 SIG BROKERAGE, LP 22.5K +22.5K (+100.0%) 2.36M +2.4M (+100.0%) 0.20% +0.203 pp 0.07% +0.073 pp USD104.67 +0.0% 1 qtrs NEW
47 WELLINGTON MANAGEMENT GROUP LLP 22.4K -1.3K (-5.5%) 2.34M +859.0K (+57.8%) 0.20% -0.012 pp 0.00% +0.000 pp USD62.69 +67.0% 2 qtrs
48 RAYMOND JAMES FINANCIAL INC 22.3K -1.6K (-6.6%) 2.33M +836.0K (+55.9%) 0.20% -0.015 pp 0.00% +0.000 pp USD62.68 +67.0% 3 qtrs
49 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 21.6K +620.0 (+3.0%) 2.26M +947.0K (+71.9%) 0.20% +0.005 pp 0.00% +0.000 pp USD24.89 +320.5% 3 qtrs
50 NUVEEN, LLC 19.6K +6.9K (+54.1%) 2.05M +1.3M (+157.3%) 0.18% +0.062 pp 0.00% +0.000 pp USD59.16 +76.9% 3 qtrs
51 AVIDITY PARTNERS MANAGEMENT LP 19.3K +19.3K (+100.0%) 2.02M +2.0M (+100.0%) 0.17% +0.174 pp 0.58% +0.583 pp USD104.67 +0.0% 1 qtrs NEW
52 NEW YORK STATE COMMON RETIREMENT FUND 17.3K +14.5K (+518.4%) 1.81M +1.6M (+932.5%) 0.16% +0.131 pp 0.00% +0.002 pp USD91.39 +14.5% 3 qtrs
53 BANK OF NEW YORK MELLON CORP 16.3K +79.0 (+0.5%) 1.70M +687.7K (+67.8%) 0.15% +0.001 pp 0.00% +0.000 pp USD29.17 +258.8% 3 qtrs
54 RAFFERTY ASSET MANAGEMENT, LLC 15.7K +15.7K (+100.0%) 1.65M +1.6M (+100.0%) 0.14% +0.142 pp 0.01% +0.006 pp USD104.67 +0.0% 1 qtrs NEW
55 SWISS NATIONAL BANK 14.2K +14.2K (+100.0%) 1.49M +1.5M (+100.0%) 0.13% +0.128 pp 0.00% +0.001 pp USD104.67 +0.0% 1 qtrs NEW
56 VICTORY CAPITAL MANAGEMENT INC 14.1K +14.1K (+100.0%) 1.48M +1.5M (+100.0%) 0.13% +0.128 pp 0.00% +0.001 pp USD104.67 +0.0% 1 qtrs NEW
57 TUDOR INVESTMENT CORP ET AL 12.5K +12.5K (+100.0%) 1.31M +1.3M (+100.0%) 0.11% +0.113 pp 0.00% +0.002 pp USD104.67 +0.0% 1 qtrs NEW
58 VERITION FUND MANAGEMENT LLC 11.9K +11.9K (+100.0%) 1.25M +1.2M (+100.0%) 0.11% +0.108 pp 0.00% +0.005 pp USD104.67 +0.0% 1 qtrs NEW
59 SEI INVESTMENTS CO 11.7K +11.7K (+100.0%) 1.23M +1.2M (+100.0%) 0.11% +0.106 pp 0.00% +0.001 pp USD104.67 +0.0% 1 qtrs NEW
60 MARINER, LLC 11.6K -9.1K (-43.9%) 1.22M -83.3K (-6.4%) 0.11% -0.083 pp 0.00% 0.000 pp USD62.69 +67.0% 2 qtrs
61 CRESSET ASSET MANAGEMENT, LLC 11.4K -6.0K (-34.4%) 1.20M +104.0K (+9.5%) 0.10% -0.054 pp 0.01% +0.000 pp USD12.00 +772.3% 5 qtrs
62 LEGATO CAPITAL MANAGEMENT LLC 11.4K +11.4K (+100.0%) 1.19M +1.2M (+100.0%) 0.10% +0.103 pp 0.10% +0.103 pp USD104.67 +0.0% 1 qtrs NEW
63 WELLS FARGO & COMPANY/MN 10.9K +3.6K (+48.8%) 1.14M +683.3K (+148.4%) 0.10% +0.032 pp 0.00% +0.000 pp USD62.94 +66.3% 5 qtrs
64 CATALIO CAPITAL MANAGEMENT, LP 10.5K -1.6K (-13.0%) 1.09M +341.1K (+45.3%) 0.09% -0.014 pp 0.19% +0.054 pp USD62.69 +67.0% 2 qtrs
65 ALPS ADVISORS INC 9.7K +4.2K (+77.1%) 1.02M +673.1K (+195.7%) 0.09% +0.038 pp 0.01% +0.004 pp USD80.97 +29.3% 2 qtrs
66 MARSHALL WACE, LLP 9.5K +9.5K (+100.0%) 992.7K +992.7K (+100.0%) 0.09% +0.086 pp 0.00% +0.001 pp USD104.67 +0.0% 4 qtrs
67 CINCTIVE CAPITAL MANAGEMENT LP 8.7K +8.7K (+100.0%) 911.4K +911.4K (+100.0%) 0.08% +0.079 pp 0.05% +0.049 pp USD104.67 +0.0% 1 qtrs NEW
68 RHUMBLINE ADVISERS 8.6K -1.2K (-12.5%) 903.9K +285.1K (+46.1%) 0.08% -0.011 pp 0.00% +0.000 pp USD22.54 +364.4% 3 qtrs
69 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 6.9K +6.5K (+1,512.8%) 724.2K +697.3K (+2,592.8%) 0.06% +0.059 pp 0.00% +0.001 pp USD99.58 +5.1% 3 qtrs
70 DEUTSCHE BANK AG\ 6.6K +528.0 (+8.7%) 690.2K +309.9K (+81.5%) 0.06% +0.005 pp 0.00% +0.000 pp USD29.12 +259.4% 3 qtrs
71 SIGMA PLANNING CORP 6.5K +6.5K (+100.0%) 680.4K +680.4K (+100.0%) 0.06% +0.059 pp 0.02% +0.019 pp USD104.67 +0.0% 1 qtrs NEW
72 BROWN ADVISORY INC 6.4K +— (+0.0%) 667.7K +267.8K (+67.0%) 0.06% 0.000 pp 0.00% +0.000 pp USD62.69 +67.0% 2 qtrs
73 ASPIRIANT, LLC 5.9K +— (+0.0%) 612.5K +245.7K (+67.0%) 0.05% 0.000 pp 0.02% +0.006 pp USD62.69 +67.0% 2 qtrs
74 LEGAL & GENERAL GROUP PLC 5.8K +5.1K (+674.7%) 612.2K +564.9K (+1,193.5%) 0.05% +0.046 pp 0.00% +0.000 pp USD94.07 +11.3% 3 qtrs
75 PROFUND ADVISORS LLC 5.8K +5.8K (+100.0%) 608.4K +608.4K (+100.0%) 0.05% +0.053 pp 0.02% +0.019 pp USD104.67 +0.0% 1 qtrs NEW
76 BREVAN HOWARD CAPITAL MANAGEMENT LP 5.7K +5.7K (+100.0%) 584.6K +584.6K (+100.0%) 0.05% +0.052 pp 0.01% +0.006 pp USD104.67 +0.0% 1 qtrs NEW
77 JPMORGAN CHASE & CO 5.0K +668.0 (+15.4%) 524.0K +252.0K (+92.7%) 0.05% +0.006 pp 0.00% +0.000 pp USD42.26 +147.7% 5 qtrs
78 FRANKLIN RESOURCES INC 4.7K +— (+0.0%) 486.7K +195.2K (+67.0%) 0.04% +0.000 pp 0.00% +0.000 pp USD62.69 +67.0% 2 qtrs
79 STATE OF WISCONSIN INVESTMENT BOARD 4.5K +4.5K (+100.0%) 472.4K +472.4K (+100.0%) 0.04% +0.041 pp 0.00% +0.001 pp USD104.67 +0.0% 1 qtrs NEW
80 MIRAE ASSET GLOBAL ETFS HOLDINGS LTD. 4.3K +1.1K (+35.7%) 446.3K +247.3K (+124.3%) 0.04% +0.010 pp 0.00% +0.000 pp USD44.13 +137.2% 3 qtrs
81 METLIFE INVESTMENT MANAGEMENT, LLC 4.3K +— (+0.0%) 445.9K +178.8K (+67.0%) 0.04% +0.000 pp 0.00% +0.001 pp USD22.54 +364.4% 3 qtrs
82 XTX TOPCO LTD 4.1K +4.1K (+100.0%) 429.5K +429.5K (+100.0%) 0.04% +0.037 pp 0.01% +0.011 pp USD104.67 +0.0% 3 qtrs
83 PRICE T ROWE ASSOCIATES INC /MD/ 4.1K +433.0 (+11.8%) 429.0K +199.0K (+86.5%) 0.04% +0.004 pp 0.00% +0.000 pp USD67.13 +55.9% 2 qtrs
84 TWO SIGMA INVESTMENTS, LP 4.1K +— (+0.0%) 428.1K +171.7K (+67.0%) 0.04% +0.000 pp 0.00% +0.000 pp USD62.69 +67.0% 2 qtrs
85 JANUS HENDERSON GROUP PLC 3.6K +3.6K (+100.0%) 376.2K +376.2K (+100.0%) 0.03% +0.033 pp 0.00% +0.000 pp USD104.67 +0.0% 1 qtrs NEW
86 LETKO, BROSSEAU & ASSOCIATES INC 3.5K -1.7K (-32.7%) 366.3K +40.4K (+12.4%) 0.03% -0.015 pp 0.01% +0.000 pp USD62.69 +67.0% 2 qtrs
87 MILLENNIUM MANAGEMENT LLC 3.5K -23.4K (-87.1%) 364.3K -1.3M (-78.4%) 0.03% -0.212 pp 0.00% -0.001 pp USD27.21 +284.7% 4 qtrs
88 INTECH INVESTMENT MANAGEMENT LLC 3.5K -659.0 (-16.0%) 363.1K +104.3K (+40.3%) 0.03% -0.006 pp 0.00% +0.001 pp USD62.69 +67.0% 2 qtrs
89 LPL FINANCIAL LLC 3.4K +3.4K (+100.0%) 360.9K +360.9K (+100.0%) 0.03% +0.031 pp 0.00% +0.000 pp USD104.67 +0.0% 1 qtrs NEW
90 BAADER BANK AKTIENGESELLSCHAFT 3.1K +3.1K (+100.0%) 326.5K +326.5K (+100.0%) 0.03% +0.028 pp 0.02% +0.022 pp USD104.67 +0.0% 1 qtrs NEW
91 CERTUITY, LLC 3.0K +3.0K (+100.0%) 314.0K +314.0K (+100.0%) 0.03% +0.027 pp 0.02% +0.020 pp USD104.67 +0.0% 1 qtrs NEW
92 PEAPACK GLADSTONE FINANCIAL CORP 3.0K +3.0K (+100.0%) 314.0K +314.0K (+100.0%) 0.03% +0.027 pp 0.00% +0.004 pp USD104.67 +0.0% 1 qtrs NEW
93 CREATIVE PLANNING 3.0K +3.0K (+100.0%) 310.1K +310.1K (+100.0%) 0.03% +0.027 pp 0.00% +0.000 pp USD104.67 +0.0% 1 qtrs NEW
94 QUEST PARTNERS LLC 2.8K +137.0 (+5.2%) 288.3K +124.2K (+75.7%) 0.02% +0.001 pp 0.02% +0.005 pp USD64.78 +61.6% 2 qtrs
95 VIRTUS INVESTMENT ADVISERS, INC. 2.7K +2.7K (+100.0%) 282.4K +282.4K (+100.0%) 0.02% +0.024 pp 0.08% +0.077 pp USD104.67 +0.0% 1 qtrs NEW
96 SG AMERICAS SECURITIES, LLC 2.7K +2.7K (+100.0%) 281.0K +281.0K (+100.0%) 0.02% +0.024 pp 0.00% +0.000 pp USD104.67 +0.0% 1 qtrs NEW
97 CITADEL ADVISORS LLC 2.6K +2.6K (+100.0%) 275.9K +275.9K (+100.0%) 0.02% +0.024 pp 0.00% +0.000 pp USD104.67 +0.0% 1 qtrs NEW
98 CHUNG WU INVESTMENT GROUP, LLC 2.6K +2.4K (+1,200.0%) 272.1K +259.6K (+2,070.5%) 0.02% +0.022 pp 0.22% +0.212 pp USD101.44 +3.2% 2 qtrs
Ownership breakdown by holder

ETF Ownership

Top ETFs holding this stock Held by 78 ETFs in our universe
# ETF Weight Est. AUM exposure TER
1 F/M Emerald Life Sciences Innovation ETF LFSC 2.02% 1.51M 0.54%
2 ALPS Medical Breakthroughs ETF SBIO 1.05% 2.24M 0.50%
3 Virtus Biotech Clinical Trials ETF BBC 0.82% 471.4K 0.65%
4 Global X - S&P Biotech ETF CURE.AX 0.55% 197.5K 0.45%
5 State Street SPDR S&P Biotech ETF XBI 0.55% 59.32M 0.35%
6 Vanguard U.S. Momentum Factor ETF VFMO 0.15% 2.48M 0.13%
7 Vanguard Global Momentum Factor ETF VMO.TO 0.12% 439.5K 0.38%
8 Pacer WealthShield ETF PWS 0.11% 27.5K 0.60%
9 T. Rowe Price Innovation Leaders ETF TNXT 0.10% 18.2K 0.49%
10 iShares Russell 2000 Growth ETF IWO 0.10% 14.70M 0.24%

Insider Activity

Insider Activity — Latest Quarter
Ratio by transactions
0.43
Bearish
Ratio by volume
1.20
Neutral
Buys
3
Sells
7
Shares acquired
10.3K
Shares disposed
8.6K
Cash buys
Cash sales
5.00
Net activity
+1,698
Insider buys vs sells (history) From To
Recent insider transactions From To
Date Person Role Transaction A/D Security Shares Price Value Owned after D/I Filing
2026-04-15 Goin Kathleen Officer M-Exempt D Stock Option (Right to Buy) 2,154 7.14 15.4K 12,935 D
2026-04-13 Doux John Director Stock Option (Right to Buy) 10,364 7.14 74.0K 0 D
2026-03-30 JENKINS GEORGE M Director P-Purchase A Common Stock 445 112.30 50.0K 187,616 D
2026-03-18 Goin Kathleen Officer M-Exempt D Stock Option (Right to Buy) 2,154 7.14 15.4K 15,089 D
2026-02-27 JENKINS GEORGE M Director P-Purchase A Common Stock 4,000 125.00 500.0K 187,171 D
2026-02-27 HERON ELAINE J Director P-Purchase A Common Stock 2,400 125.00 300.0K 47,812 D
2026-02-18 Goin Kathleen Officer M-Exempt A Common Stock 2,148 9.08 19.5K 4,302 D
2026-02-05 Martini Jeffrey S Officer A-Award A Stock Option (Right to Buy) 64,318 76.43 4.92M 64,318 D
2026-02-05 Korenberg Matthew E Officer A-Award A Stock Option (Right to Buy) 44,123 76.43 3.37M 44,123 D
2026-02-05 Kline Ashley Hartmann Officer A-Award A Stock Option (Right to Buy) 38,517 76.43 2.94M 38,517 D
2026-02-05 Kaupinen Wes Director / Officer / 10% Owner A-Award A Stock Option (Right to Buy) 124,603 76.43 9.52M 124,603 D
2026-02-05 Goin Kathleen Officer A-Award A Stock Option (Right to Buy) 48,956 76.43 3.74M 48,956 D
2026-01-21 Goin Kathleen Officer M-Exempt D Stock Option (Right to Buy) 2,154 7.14 15.4K 19,397 D
2025-12-17 Goin Kathleen Officer M-Exempt A Common Stock 2,148 9.08 19.5K 4,302 D
2025-11-19 Goin Kathleen Officer M-Exempt D Stock Option (Right to Buy) 2,154 7.14 15.4K 23,705 D
2025-06-10 Wessel Tadd S. Director A-Award A Non-Qualified Stock Option (right to buy) 12,350 26.23 323.9K 12,350 D
2025-06-10 KIRITSY CHRISTOPHER P Director A-Award A Non-Qualified Stock Option (right to buy) 12,350 26.23 323.9K 12,350 D
2025-06-10 JENKINS GEORGE M Director A-Award A Non-Qualified Stock Option (right to buy) 12,350 26.23 323.9K 12,350 D
2025-06-10 HERON ELAINE J Director A-Award A Non-Qualified Stock Option (right to buy) 12,350 26.23 323.9K 12,350 D
2025-06-10 Davis Todd C Director A-Award A Non-Qualified Stock Option (right to buy) 12,350 26.23 323.9K 12,350 D
2025-05-27 Kline Ashley Hartmann Officer A-Award A Incentive Stock Option (right to buy) 17,436 22.94 400.0K 17,436 D
2025-04-09 JENKINS GEORGE M Director P-Purchase A Common Stock 2,500 20.13 50.3K 183,171 D
2025-02-05 PALVELLA THERAPEUTICS, INC. Director / Officer A-Award A Non-Qualified Stock Option (right to buy) 243,831 14.76 3.60M 243,831 D
2025-02-05 Martini Jeffrey S Officer A-Award A Non-Qualified Stock Option (right to buy) 123,559 14.76 1.82M 123,559 D
2025-02-05 Korenberg Matthew E Officer A-Award A Incentive Stock Option (right to buy) 5,373 14.76 79.3K 5,373 D
2025-02-05 Kaupinen Wes Director / Officer A-Award A Non-Qualified Stock Option (right to buy) 243,831 14.76 3.60M 243,831 D
2025-02-05 Goin Kathleen Officer A-Award A Non-Qualified Stock Option (right to buy) 123,559 14.76 1.82M 123,559 D
2024-12-18 JENKINS GEORGE M Director P-Purchase A Common Stock 4,000 12.93 51.7K 180,671 D
2024-12-13 Wessel Tadd S. Director A-Award A Stock Option (right to buy) 24,700 13.60 335.9K 24,700 D
2024-12-13 Martini Jeffrey S Officer Stock Option (right to buy) 18,541 9.79 181.5K 0 D
2024-12-13 Korenberg Matthew E Officer A-Award A Stock Option (right to buy) 167,100 13.60 2.27M 167,100 D
2024-12-13 Kaupinen Wes Director / Officer / 10% Owner Stock Option (right to buy) 81,459 7.53 613.4K 0 D
2024-12-13 KIRITSY CHRISTOPHER P Director A-Award A Stock Option (right to buy) 24,700 13.60 335.9K 24,700 D
2024-12-13 JENKINS GEORGE M Director Common Stock 0 0.00 11,026 I
2024-12-13 HERON ELAINE J Director Stock Option (right to buy) 4,642 7.14 33.1K 0 D
2024-12-13 Goin Kathleen Officer Stock Option (right to buy) 85,974 9.79 841.7K 0 D
2024-12-13 Dellora Investments LP 0 0.00 0
2024-12-13 Davis Todd C Director Common Stock 0 0.00 112,547 D
2024-12-13 BVF PARTNERS L P/IL Other J-Other A Common Stock, $0.001 par value 234,323 0.00 371,916 D

Executive team

Top executives
Shares Outstanding
11.84M

Executive compensation

Executive compensation (annual)
# Year Executive Salary Bonus Stock award Option award Incentive Other Total % Stock-
based
Filing
1 2025 Wesley H. Kaupinen President and Chief Executive Officer 575.0K 2.47M 359.4K 643.00 3.40M 72.54%
2 2025 Kathleen Goin Chief Operating Officer 481.3K 1.31M 192.5K 1.98M 65.97%
3 2025 Matthew E. Korenberg Chief Financial Officer 475.3K 1.31M 190.1K 1.97M 66.25%
4 2024 Wesley H. Kaupinen President and Chief Executive Officer 384.9K 515.5K 4.53M 643.00 5.44M 83.42%
5 2024 Kathleen Goin Chief Operating Officer 381.4K 257.5K 485.6K 1.12M 43.18%
CEO compensation breakdown

Proxy statements

Proxy statements (DEF 14A)
Filing date Form type Filing
2026-04-30 DEFA14A
2026-04-30 DEF 14A
2025-04-30 DEFA14A
2025-04-30 DEF 14A

Recent SEC filings

Recent SEC filings
Filing date Form type Filing
2026-04-30 DEFA14A
2026-04-30 DEF 14A
2026-04-30 ARS
2026-04-17 4
2026-04-15 4
2026-04-15 3
2026-04-13 8-K
2026-04-07 8-K
2026-04-01 4
2026-03-31 8-K

Executive team

NameTitleCompensationGender
Wesley H. Kaupinen Founder, President, Chief Executive Officer & Director 935.0K male
Kathleen Goin Chief Operating Officer 639.0K female
Jeffrey Martini Chief Scientific Officer 530.4K
Emily Cook Senior Vice President of Clinical Operations female
Jason Burdette SVP of CMC & Technical Operations male
Ashley Kline Chief Commercial Officer female
Kent Taylor Senior Vice President of Sales male
Matthew E. Korenberg Chief Financial Officer & Treasurer male
Sarah Foster Senior Vice President of Human Resources female
Vimal Patel Senior VP of Medical Affairs
Jennifer McDonough Senior Vice President of Market Access & Patient Services female
Bohan Wei Vice President of Corporate Development & New Product Planning female
ESG Rating
B
BIOTECHNOLOGY
2025
E (Environmental)
56.6 / 56.3
Company / Sector avg.
S (Social)
64.0 / 62.4
Company / Sector avg.
G (Governance)
64.6 / 60.9
Company / Sector avg.
ESG Total
61.7 / 59.9
Company / Sector avg.
ESG Score History BIOTECHNOLOGY
Benchmark vs Sector
Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend history

Earnings history

Earnings reports

Stock splits