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Mesoblast Limited (MSB.AX)

AUD2.59 +0.21 (+8.82%)
AU ASX Healthcare Biotechnology
Address 55 Collins Street 3000
Melbourne, VIC, AU
CEO Silviu Itescu
IPO 2004-12-15
ISIN AU000000MSB8

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Also trades on Australian Securities Exchange · MSB.AX (AUD) NASDAQ Global Select · MESO (USD) Other OTC · MEOBF (USD)
Description

Mesoblast Limited, an Australian enterprise established in Melbourne in 2004, is dedicated to developing innovative regenerative medicine products. The company's global reach extends to the United States, Singapore, the United Kingdom, and Switzerland. Its therapeutic endeavors encompass a wide array of medical conditions, including cardiovascular diseases, spinal and orthopedic ailments, oncology, hematology, and immune-mediated and inflammatory disorders. Mesoblast's distinctive regenerative medicine platform is founded on the therapeutic potential of specialized mesenchymal lineage cells. A prominent candidate, Remestemcel-L, is currently in late-stage (Phase III) clinical trials for various systemic inflammatory conditions, such as steroid-refractory acute graft versus host disease, acute respiratory distress syndrome, and biologic-refractory inflammatory bowel disease. Additionally, Remestemcel-L is undergoing Phase III evaluation for chronic heart failure and chronic low back pain linked to degenerative disc disease. The company's pipeline also features MPC-300-IV, under development for biologic-refractory rheumatoid arthritis and diabetic nephropathy, and MPC-25-IC, aimed at treating or preventing acute myocardial infarction. Mesoblast has forged key strategic partnerships, including one with Tasly Pharmaceutical Group for the commercialization of MPC-150-IM (for heart failure) and MPC-25-IC (for heart attacks) in China. It also collaborates with JCR Pharmaceuticals Co. Ltd. on wound healing therapies for epidermolysis bullosa patients, and with Grünenthal to advance and market a cell therapy for chronic low back pain.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
AUD2.59 +0.21 (+8.82%)
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Volume Profile
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Liquidity & share structure
Average Volume
3M
Beta
0.79
Float Shares
819.92M
Free Float %
63.4%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
+5.42% +0.94% +0.94% -4.46% -21.03% -21.32% +33.75% +122.37% +15.05% +15.68% +245.44%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Analyst Consensus (9 ratings, all time) Hold
Price Targets & DCF
Current price
2.59
Ratings Trend (MoM) 100% Bullish
Rating 2026-05 Change
Strong Buy 1 0
Buy 5 0
Hold 0 0
Sell 0 0
Strong Sell 0 0
Quality scores
Altman Z-Score
3.74
Safe zone
Piotroski F-Score
3 / 9
Average
MOAT Score
1 / 10
No MOAT
Composite Rating
D+
Overall Score
1 / 5
Low
DCF Score
1 / 5
Low
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
1 / 5
Low
P/E Score
1 / 5
Low
P/Book Score
1 / 5
Low
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
    +191.4% Q2'25: +458.6% (vs Q2'24)
  • EPS growth Biotechnology: +29.7%
    -0.3% Q2'25: +13.8% (vs Q2'24)
  • FCF margin FCF growth · Biotechnology: +16.2%
    -578.6% Q2'25: -63.6% (vs Q2'24)
  • EBIT margin Biotechnology: +0.0%
    -465.5% Q2'25: -302.4% (vs Q2'24)
  • ROIC Biotechnology: -16.1%
    -14.2% Q2'25: -14.6% (vs Q2'24)
  • Share dilution Biotechnology: -3.4%
    +15.8% Q2'25: +13.5% (vs Q2'24)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    -1.74× Q2'25: -1.72× (vs Q2'24)
Valuation Multiples From To
Price Forecast (3Y) From To
Model
Adjust
P/E
Theoretical Return — If Invested Today

* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.

DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (0.79) × ERP
WACC = 93% × Ke + 7% × Kd (17.0%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Current price: 2.59
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Jun 2015
actual
Jun 2016
actual
Jun 2017
actual
Jun 2018
actual
Jun 2019
actual
Jun 2020
actual
Jun 2021
actual
Jun 2022
actual
Jun 2023
actual
Jun 2024
actual
Jun 2025
actual
Jun 2026
7 Rev. Ana.
3 EPS Ana.
Jun 2027
7 Rev. Ana.
4 EPS Ana.
Jun 2028
5 Rev. Ana.
4 EPS Ana.
Jun 2029
2 Rev. Ana.
1 EPS Ana.
Jun 2030
2 Rev. Ana.
1 EPS Ana.
Revenue
23.75M
est: 22.05M (+7.7%)
42.55M
est: 20.67M (+105.9%)
2.41M
est: 4.24M (-43.1%)
17.34M
est: 16.32M (+6.3%)
16.72M
est: 16.25M (+2.9%)
32.16M
est: 44.46M (-27.7%)
7.46M
est: 27.23M (-72.6%)
10.21M
est: 13.84M (-26.2%)
7.50M
est: 8.39M (-10.5%)
5.90M
est: 7.49M (-21.2%)
17.20M
est: 17.40M (-1.2%)
120.65M
112.02M – 140.03M
+593.3% YoY
206.75M
137.34M – 307.92M
+71.4% YoY
398.10M
302.95M – 545.03M
+92.6% YoY
874.25M
665.30M – 1.20B
+119.6% YoY
852.11M
648.46M – 1.17B
-2.5% YoY
EBITDA
-90.19M
est: -22.05M (-309.1%)
-28.07M
est: -20.67M (-35.8%)
-87.16M
est: -4.24M (-1,957.2%)
-74.69M
est: -16.32M (-357.7%)
-84.54M
est: -16.25M (-420.1%)
-68.97M
est: -44.46M (-55.1%)
-84.65M
est: -27.23M (-210.9%)
-76.57M
est: -13.84M (-453.1%)
-58.55M
est: -8.39M (-598.3%)
-56.08M
est: -7.49M (-648.4%)
-73.66M
est: -17.40M (-323.3%)
-120.65M
-140.03M – -112.02M
-593.3% YoY
-206.75M
-307.92M – -137.34M
-71.4% YoY
-398.10M
-545.03M – -302.95M
-92.6% YoY
-874.25M
-1.20B – -665.30M
-119.6% YoY
-852.11M
-1.17B – -648.46M
+2.5% YoY
EBIT
-91.39M
est: -22.05M (-314.5%)
-90.82M
est: -20.67M (-339.5%)
-90.22M
est: -4.24M (-2,029.3%)
-64.15M
est: -16.32M (-293.1%)
-86.67M
est: -16.25M (-433.3%)
-72.64M
est: -44.46M (-63.4%)
-88.92M
est: -27.23M (-226.5%)
-74.30M
est: -13.84M (-436.6%)
-62.66M
est: -8.39M (-647.2%)
-57.97M
est: -7.49M (-673.7%)
-80.06M
est: -17.40M (-360.1%)
-120.65M
-140.03M – -112.02M
-593.3% YoY
-206.75M
-307.92M – -137.34M
-71.4% YoY
-398.10M
-545.03M – -302.95M
-92.6% YoY
-874.25M
-1.20B – -665.30M
-119.6% YoY
-852.11M
-1.17B – -648.46M
+2.5% YoY
Net Income
-119.37M
est: -231.43M (+48.4%)
-4.13M
est: -194.27M (+97.9%)
-76.82M
est: -84.53M (+9.1%)
-35.29M
est: -105.07M (+66.4%)
-89.80M
est: -206.84M (+56.6%)
-77.94M
est: -134.23M (+41.9%)
-98.81M
est: -150.74M (+34.4%)
-91.35M
est: -120.88M (+24.4%)
-81.89M
est: -122.56M (+33.2%)
-87.96M
est: -58.65M (-50.0%)
-102.14M
est: -66.71M (-53.1%)
-40.06M
-42.18M – -17.07M
+40.0% YoY
16.39M
-3.68M – 19.60M
+140.9% YoY
138.01M
-12.65M – 166.30M
+742.2% YoY
157.02M
108.24M – 232.36M
+13.8% YoY
361.26M
249.02M – 534.60M
+130.1% YoY
SGA
65.38M
est: 121.59M (-46.2%)
52.26M
est: 113.97M (-54.1%)
35.07M
est: 23.36M (+50.1%)
27.42M
est: 89.99M (-69.5%)
36.98M
est: 89.63M (-58.7%)
50.92M
est: 245.18M (-79.2%)
63.59M
est: 150.17M (-57.7%)
57.97M
est: 76.35M (-24.1%)
53.11M
est: 46.24M (+14.8%)
23.63M
est: 41.32M (-42.8%)
39.31M
est: 95.96M (-59.0%)
665.33M
617.78M – 772.21M
+593.3% YoY
1.14B
757.42M – 1.70B
+71.4% YoY
2.20B
1.67B – 3.01B
+92.6% YoY
4.82B
3.67B – 6.60B
+119.6% YoY
4.70B
3.58B – 6.43B
-2.5% YoY
EPS
-0.22
est: -0.20 (-8.6%)
-0.01
est: -0.17 (+95.5%)
-0.14
est: -0.07 (-89.2%)
-0.07
est: -0.09 (+28.7%)
-0.17
est: -0.18 (+6.1%)
-0.14
est: -0.12 (-19.1%)
-0.16
est: -0.13 (-21.2%)
-0.14
est: -0.11 (-32.3%)
-0.11
est: -0.11 (-2.5%)
-0.09
est: -0.05 (-70.3%)
-0.09
est: -0.06 (-52.7%)
-0.03
-0.04 – -0.01
+52.1% YoY
0.01
0.00 – 0.02
+120.2% YoY
0.06
-0.01 – 0.15
+928.1% YoY
0.14
0.09 – 0.20
+135.5% YoY
0.32
0.22 – 0.47
+130.1% YoY
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-29 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-28 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-27 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-26 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-25 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-22 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-21 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-20 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-19 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-18 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-15 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-14 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-13 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-12 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-11 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-08 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-07 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-06 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-05 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-05-04 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-05-01 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-04-30 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-04-29 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-04-28 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-04-27 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-04-24 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-04-23 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-22 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-21 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-20 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-17 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-16 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
-28.33M
OE per share TTM
-0.02
Owner's Yield
-1.04%
Maintenance CapEx ratio
Maint CapEx / Avg PPE
50.8%

Ownership Overview

Ownership breakdown

Ownership breakdown not available.

At a glance
Institutional holders
Total invested
Insider transactions (90d)
0
Beneficial owners (>5%)
0
Beneficial owners (>5%)

No beneficial ownership filings recorded.

Institutional Activity (13F)

Institutional ownership trend

Institutional history not available.

Top institutional holders

Top holders not available.

ETF Ownership

Top ETFs holding this stock Held by 77 ETFs in our universe
# ETF Weight Est. AUM exposure TER
1 iShares S&P/ASX Small Ordinaries ETF ISO.AX 0.76% 663.6K 0.55%
2 BetaShares - Australian Sustainability Leaders ETF FAIR.AX 0.52% 3.87M 0.49%
3 Vanguard MSCI Australian Small Companies Index ETF VSO.AX 0.33% 2.62M 0.30%
4 BetaShares - Australian Ex-20 Portfolio Diversifier ETF EX20.AX 0.20% 908.9K 0.25%
5 BetaShares - Geared Australian Equities Complex ETF GEAR.AX 0.17% 758.6K 0.78%
6 BetaShares - Managed Risk Australian Shares Complex ETF AUST.AX 0.08% 15.1K 0.49%
7 iShares Core S&P/ASX 200 ETF IOZ.AX 0.08% 4.97M 0.05%
8 Vanguard Australian Shares Index ETF VAS.AX 0.08% 13.45M 0.07%
9 Goldman Sachs Innovate Equity ETF GINN 0.08% 158.6K 0.50%
10 BetaShares - Australia 200 ETF A200.AX 0.07% 5.05M 0.04%

Insider Activity

Insider Activity — Latest Quarter

No insider activity available.

Insider buys vs sells (history)

Insider history not available.

Recent insider transactions

No recent insider transactions.

Executive team

Top executives
EBIT / Employee
-11.0K
Shares Outstanding
1.29B

Executive compensation

Executive compensation (annual)

Executive compensation not available.

CEO compensation breakdown

No CEO compensation history available.

Proxy statements

Proxy statements (DEF 14A)

No proxy statements available for this company yet.

Recent SEC filings

Recent SEC filings

No SEC filings available for this company yet.

Executive team

NameTitleCompensationGender
Silviu Itescu FACP FACRA FRACP MBBS Founder, Chief Executive Officer, MD, Chairman of Scientific Advisory Board & Executive Director 2M
Eric A. Rose Chief Medical Officer & Executive Director 1M
Geraldine Storton Head of Regulatory Affairs & Quality Management female
James Michael O'Brien Chief Financial Officer male
Daniel Devine Head of Special Projects male
Marcelo Santoro Chief Commercial Officer male
Paul Hughes BPHARM Global Head of Corporate Communications & Joint Company Secretary male
Paul J. Simmons Scientific Advisor to the Chief Executive Officer
Peter T. Howard General Counsel & Corporate Executive male
Justin Horst Head of Manufacturing male
Fiona See Senior Vice President & Head of Translational Research
ESG Score History

No data available for this company.

Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend history

Earnings history

Earnings reports

Stock splits