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IDEAYA Biosciences, Inc. (IDYA)

USD36.66 +0.01 (+0.03%)
US NASDAQ Healthcare Biotechnology
Address 7000 Shoreline Court 94080
South San Francisco, CA, US
CEO Yujiro S. Hata
IPO 2019-05-23
CIK 1676725 ISIN US45166A1025

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Description

IDEAYA Biosciences, Inc. is a precision oncology company primarily dedicated to identifying and advancing targeted therapies, particularly leveraging the concept of synthetic lethality. The firm aims to develop specific treatments for patient groups selected through molecular diagnostic methods. At the forefront of its clinical efforts are two investigational drugs. IDE397, a methionine adenosyltransferase 2a (MAT2A) blocking agent, is currently in early-stage (Phase I) trials for solid tumors exhibiting methylthioadenosine phosphorylase (MTAP) deletions. Its second primary candidate, IDE196, a protein kinase C (PKC) inhibitor, is progressing through Phase I/II studies, targeting genetically defined cancers characterized by GNAQ or GNA11 gene mutations. Beyond its clinical pipeline, IDEAYA's earlier-stage portfolio includes several synthetic lethality programs. These encompass a PARG inhibitor designed to address tumors with specific genetic or molecular biomarkers, Pol Theta inhibitors aimed at cancers presenting with BRCA or other homologous recombination deficiency (HRD) mutations, and WRN inhibitors for tumors demonstrating high microsatellite instability (MSI-H). The company also engages in significant collaborations. It has a joint research effort with Cancer Research UK and the University of Manchester, focusing on small molecule inhibitors of Poly (ADP-ribose) glycohydrolase. Furthermore, IDEAYA maintains a partnership with Pfizer Inc. for the clinical development and supply in Phase I/II trials across metastatic uveal melanoma, skin melanoma, and other solid tumors, alongside a strategic alliance with GlaxoSmithKline plc. IDEAYA Biosciences, Inc. was established in 2015 and operates from its headquarters in South San Francisco, California.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
USD36.66 +0.01 (+0.03%)
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Volume Profile
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Liquidity & share structure
Average Volume
1M
Beta
-0.05
Float Shares
86.96M
Free Float %
99.0%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
-0.04% -0.04% -7.80% -10.79% -11.99% -18.66% +53.24% +31.40% +45.40% +151.30% +151.30%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
vs.
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Analyst Consensus (25 ratings, all time) Buy
Price Targets & DCF
Current price
36.66
Low 53.00 +44.6%
Consensus 58.67 +60.0%
Median 58.00 +58.2%
High 65.00 +77.3%
Ratings Trend (MoM) 89% Bullish
Rating 2026-05 Change
Strong Buy 3 0
Buy 13 0
Hold 2 0
Sell 0 0
Strong Sell 0 0
Price Target Summary
Period # Analysts Avg Target
Last Month 3
58.67
+60.0%
Last Quarter 4
57.00
+55.5%
Last Year 14
47.71
+30.1%
All Time 30
47.60
+29.8%
Quality scores
Altman Z-Score
15.16
Safe zone
Piotroski F-Score
3 / 9
Average
MOAT Score
1 / 10
No MOAT
Composite Rating
C-
Overall Score
1 / 5
Low
DCF Score
1 / 5
Low
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
3 / 5
Medium
P/E Score
1 / 5
Low
P/Book Score
2 / 5
Medium
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
    +3,024.4%
  • EPS growth Biotechnology: +29.7%
    +61.9% Q1'26: -35.4% (vs Q1'25)
  • FCF margin FCF growth · Biotechnology: +16.2%
    -71.0% Q1'26: -1,160.6% (vs Q1'25)
  • EBIT margin Biotechnology: +0.0%
    -72.8% Q1'26: -1,654.6% (vs Q1'25)
  • ROIC Biotechnology: -16.1%
    -38.7% Q1'26: -147.3% (vs Q1'25)
  • Share dilution Biotechnology: -3.4%
    +8.3% Q1'26: +0.4% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    -0.18× Q1'26: -0.07× (vs Q1'25)
Valuation Multiples From To
Price Forecast (3Y) From To
Model
Adjust
P/E
Theoretical Return — If Invested Today

* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.

DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (-0.05) × ERP
WACC = 99% × Ke + 1% × Kd (4.1%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Current price: 36.66
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2020
actual
Dec 2021
actual
Dec 2022
actual
Dec 2023
actual
Dec 2024
actual
Dec 2025
actual
Dec 2026
11 Rev. Ana.
12 EPS Ana.
Dec 2027
11 Rev. Ana.
12 EPS Ana.
Dec 2028
12 Rev. Ana.
10 EPS Ana.
Dec 2029
11 Rev. Ana.
4 EPS Ana.
Dec 2030
6 Rev. Ana.
4 EPS Ana.
Revenue
19.54M
est: 16.91M (+15.5%)
27.94M
est: 33.97M (-17.7%)
50.93M
est: 53.92M (-5.5%)
23.39M
est: 11.96M (+95.5%)
7.00M
est: 4.67M (+50.0%)
218.71M
est: 216.88M (+0.8%)
34.69M
5.87M – 56.05M
-84.0% YoY
115.22M
23.23M – 165.71M
+232.2% YoY
267.84M
264.74M – 270.95M
+132.5% YoY
584.89M
102.22M – 1.05B
+118.4% YoY
1.03B
179.34M – 1.84B
+75.5% YoY
EBITDA
-33.11M
est: -16.91M (-95.8%)
-48.04M
est: -33.97M (-41.4%)
-56.55M
est: -53.92M (-4.9%)
-108.95M
est: -11.26M (-867.5%)
-270.64M
est: -4.39M (-6,059.8%)
-154.72M
est: -204.19M (+24.2%)
-32.66M
-52.77M – -5.53M
+84.0% YoY
-108.48M
-156.01M – -21.87M
-232.2% YoY
-252.17M
-255.09M – -249.24M
-132.5% YoY
-550.67M
-989.27M – -96.24M
-118.4% YoY
-966.15M
-1.74B – -168.85M
-75.5% YoY
EBIT
-34.50M
est: -16.91M (-104.0%)
-49.76M
est: -33.97M (-46.5%)
-58.66M
est: -53.92M (-8.8%)
-112.96M
est: -11.31M (-898.7%)
-274.48M
est: -4.41M (-6,119.4%)
-159.31M
est: -205.10M (+22.3%)
-32.81M
-53.01M – -5.56M
+84.0% YoY
-108.97M
-156.71M – -21.96M
-232.2% YoY
-253.29M
-256.23M – -250.36M
-132.5% YoY
-553.12M
-993.68M – -96.67M
-118.4% YoY
-970.46M
-1.74B – -169.60M
-75.5% YoY
Net Income
-34.50M
est: -116.53M (+70.4%)
-49.76M
est: -100.27M (+50.4%)
-58.66M
est: -143.58M (+59.1%)
-112.96M
est: -153.74M (+26.5%)
-274.48M
est: -217.38M (-26.3%)
-113.70M
est: -102.40M (-11.0%)
-403.75M
-437.82M – -299.42M
-294.3% YoY
-377.99M
-389.99M – -109.60M
+6.4% YoY
-320.96M
-328.24M – -190.84M
+15.1% YoY
-69.31M
-141.08M – 5.05M
+78.4% YoY
187.98M
-13.69M – 382.63M
+371.2% YoY
SGA
13.80M
est: 26.70M (-48.3%)
18.33M
est: 53.64M (-65.8%)
21.80M
est: 85.14M (-74.4%)
24.30M
est: 17.89M (+35.8%)
35.47M
est: 6.98M (+408.1%)
63.32M
est: 324.42M (-80.5%)
51.89M
8.79M – 83.85M
-84.0% YoY
172.36M
34.74M – 247.87M
+232.2% YoY
400.65M
396.01M – 405.30M
+132.5% YoY
874.91M
152.90M – 1.57B
+118.4% YoY
1.54B
268.27M – 2.76B
+75.5% YoY
EPS
-1.31
est: -1.43 (+8.2%)
-1.41
est: -1.23 (-14.9%)
-1.42
est: -1.43 (+1.0%)
-1.96
est: -2.21 (+11.2%)
-3.36
est: -2.47 (-36.2%)
-1.28
est: -1.29 (+0.5%)
-4.38
-4.95 – -3.38
-240.0% YoY
-3.74
-4.41 – -1.24
+14.4% YoY
-2.90
-3.71 – -2.16
+22.6% YoY
-0.78
-1.59 – 0.06
+73.0% YoY
2.12
-0.15 – 4.32
+371.2% YoY
Recent Grade Changes (3M)
Date Firm Previous New Grade Action
2026-05-07 Mizuho Outperform Outperform Maintain
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-11 C- 1/5 1/5 1/5 1/5 3/5 1/5 2/5
2026-05-08 C- 1/5 1/5 1/5 1/5 3/5 1/5 2/5
2026-05-07 C- 1/5 1/5 1/5 1/5 3/5 1/5 2/5
2026-05-06 C- 1/5 1/5 1/5 1/5 3/5 1/5 2/5
2026-05-05 C- 1/5 1/5 1/5 1/5 3/5 1/5 2/5
2026-05-04 C- 1/5 1/5 1/5 1/5 3/5 1/5 2/5
2026-05-01 C- 1/5 1/5 1/5 1/5 3/5 1/5 2/5
2026-04-30 C- 1/5 1/5 1/5 1/5 3/5 1/5 2/5
2026-04-29 C- 1/5 1/5 1/5 1/5 2/5 1/5 2/5
2026-04-28 C- 1/5 1/5 1/5 1/5 2/5 1/5 2/5
2026-04-27 C- 1/5 1/5 1/5 1/5 2/5 1/5 2/5
2026-04-24 C- 1/5 1/5 1/5 1/5 2/5 1/5 2/5
2026-04-23 C- 1/5 1/5 1/5 1/5 2/5 1/5 2/5
2026-04-22 C- 1/5 1/5 1/5 1/5 2/5 1/5 2/5
2026-04-21 C- 1/5 1/5 1/5 1/5 2/5 1/5 2/5
2026-04-20 C- 1/5 1/5 1/5 1/5 2/5 1/5 2/5
2026-04-17 C- 1/5 1/5 1/5 1/5 2/5 1/5 3/5
2026-04-16 C- 1/5 1/5 1/5 1/5 2/5 1/5 3/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
-89.00M
OE per share TTM
-1.03
Owner's Yield
-3.57%
Maintenance CapEx ratio
Maint CapEx / Avg PPE
30.0%

Ownership Overview

Ownership breakdown
At a glance
Institutional holders
34
Total invested
40.84M
Insider transactions (90d)
0
Beneficial owners (>5%)
35
Beneficial owners (>5%)
# Reporting person Amount owned % of class Sole voting Shared voting Sole dispositive Shared dispositive Type Citizenship Filing date SEC filing
1 Abigail P. Johnson 8.16M 11.07% 8.16M IN United States of America 2024-02-12
2 FMR LLC 8.16M 11.07% 8.16M 8.16M HC Delaware 2024-02-12
3 52-0556948 3.57M 5.50% 705.4K 3.57M IA Maryland 2024-02-14
4 EIN #00-0000000 3.55M 5.50% 3.55M 3.55M IA, HC Jersey, Channel Islands 2024-02-14
5 The Vanguard Group - 23-1945930 3.48M 5.39% 3.34M 134.5K IA Pennsylvania 2024-02-13
6 Arsani William 2.65M 11.00% 2.65M HC, IN Delaware 2022-03-18
7 Logos GP LLC 2.65M 11.00% 2.65M OO Delaware 2022-03-18
8 Logos Global Management GP LLC 2.65M 11.00% 2.65M HC, OO Delaware 2022-03-18
9 Logos Global Management LP 2.65M 11.00% 2.65M IA, PN Delaware 2022-03-18
10 Logos Global Master Fund LP 2.65M 11.00% 2.65M PN Delaware 2022-03-18
11 Adage Capital Advisors, L.L.C. 2.60M 5.41% 2.60M OO Delaware 2023-02-27
12 Adage Capital Partners GP, L.L.C. 2.60M 5.41% 2.60M OO Delaware 2023-02-27
13 Adage Capital Partners, L.P. 2.60M 5.41% 2.60M PN Delaware 2023-02-27
14 Phillip Gross 2.60M 5.41% 2.60M IN United States 2023-02-27
15 Robert Atchinson 2.60M 5.41% 2.60M IN United States 2023-02-27
16 Avidity Capital Partners (GP) LLC 2.55M 6.60% 2.55M 2.55M OO Delaware 2022-02-14
17 BVF Inc. 2.46M 5.10% 2.46M CO Delaware 2023-03-24
18 BVF Partners L.P. 2.46M 5.10% 2.46M IA, PN Delaware 2023-03-24
19 Mark N. Lampert 2.46M 5.10% 2.46M IN Delaware 2023-03-24
20 BVF GP Holdings LLC 2.31M 4.80% 2.31M OO Delaware 2023-03-24
21 J. Christopher Donahue 2.29M 5.95% 2.29M 2.29M IN Citizenship or place of Organization 2022-02-14
22 Rhodora J. Donahue 2.29M 5.95% 2.29M 2.29M IN Citizenship or place of Organization 2022-02-14
23 Thomas R. Donahue 2.29M 5.95% 2.29M 2.29M IN Citizenship or place of Organization 2022-02-14
24 Steven A. Cohen 2.05M 4.00% 2.05M 2.05M IN Delaware 2022-02-18
25 Point72 Asset Management, L.P. 2.05M 4.00% 2.05M 2.05M PN Delaware 2022-02-18
26 Point72 Capital Advisors, Inc. 2.05M 4.00% 2.05M 2.05M CO Delaware 2022-02-18
27 Avidity Master Fund LP 2.04M 5.30% 2.04M 2.04M PN, OO Delaware 2022-02-14
28 Biotechnology Value Fund, L.P. 1.31M 2.70% 1.31M PN Delaware 2023-03-24
29 BVF I GP LLC 1.06M 2.80% 1.06M OO Delaware 2022-05-02
30 BVF II GP LLC 996.1K 2.10% 996.1K OO Delaware 2023-03-24
31 Biotechnology Value Fund II, L.P. 996.1K 2.10% 996.1K PN Delaware 2023-03-24
32 BVF Partners OS Ltd. 112.7K 1.00% 112.7K CO Delaware 2023-03-24
33 Biotechnology Value Trading Fund OS LP 112.7K 1.00% 112.7K PN Delaware 2023-03-24
34 Cubist Systematic Strategies, LLC 2.2K 4.00% 2.2K 2.2K OO Delaware 2022-02-18
35 Point72 Hong Kong Limited 1.8K 4.00% 1.8K 1.8K OO Delaware 2022-02-18

Institutional Activity (13F)

Institutional ownership trend From To
13F snapshot — 2026 Q1
Investors holding
34
-218 vs prev Q
New positions
3
Closed positions
213
Increased
11
Reduced
9
Put/Call ratio
0.00
Calls held
Puts held
Top institutional holders
# Investor Shares / Δ Mkt value / Δ Own% / Δ Weight% / Δ Avg px / Perf. Hold / Status
1 FMR LLC 13.15M +3.4K (+0.0%) 454.59M +96.9M (+27.1%) 14.67% -0.193 pp 0.02% +0.005 pp USD38.72 -10.7% 20 qtrs
2 BLACKROCK, INC. 8.21M +82.2K (+1.0%) 283.80M +62.7M (+28.3%) 9.28% +0.092 pp 0.00% +0.001 pp USD29.97 +15.3% 6 qtrs
3 JANUS HENDERSON GROUP PLC 7.19M +758.1K (+11.8%) 248.34M +73.4M (+42.0%) 8.02% +0.750 pp 0.11% +0.031 pp USD29.21 +18.3% 18 qtrs
4 CAPITAL RESEARCH GLOBAL INVESTORS 5.28M -1.3M (-19.4%) 182.52M +4.2M (+2.4%) 5.89% -1.518 pp 0.03% +0.000 pp USD24.18 +43.0% 11 qtrs
5 VANGUARD GROUP INC 5.02M +97.1K (+2.0%) 173.52M +39.6M (+29.6%) 5.67% +0.109 pp 0.00% +0.001 pp USD26.08 +32.6% 27 qtrs
6 STATE STREET CORP 4.13M +893.7K (+27.6%) 142.93M +54.7M (+62.1%) 4.67% +1.010 pp 0.00% +0.002 pp USD27.71 +24.8% 23 qtrs
7 BAKER BROS. ADVISORS LP 3.62M +343.4K (+10.5%) 125.10M +36.0M (+40.4%) 4.09% +0.388 pp 0.73% +0.089 pp USD23.04 +50.0% 14 qtrs
8 FEDERATED HERMES, INC. 3.40M -1.2M (-26.6%) 117.39M -8.5M (-6.7%) 3.79% -1.441 pp 0.20% -0.026 pp USD25.91 +33.4% 22 qtrs
9 ADAGE CAPITAL PARTNERS GP, L.L.C. 2.80M -100.1K (-3.5%) 96.80M +17.9M (+22.7%) 3.16% -0.114 pp 0.15% +0.022 pp USD24.53 +40.9% 20 qtrs
10 FIERA CAPITAL CORP 2.44M +599.3K (+32.6%) 84.26M +34.2M (+68.5%) 2.72% +0.641 pp 0.27% +0.106 pp USD34.94 -1.1% 8 qtrs
11 DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C) 2.15M +— (+0.0%) 74.43M +15.8M (+27.0%) 2.43% 0.000 pp 0.95% +0.056 pp USD21.08 +64.0% 14 qtrs
12 GEODE CAPITAL MANAGEMENT, LLC 2.07M -76.5K (-3.6%) 71.69M +13.2M (+22.5%) 2.34% -0.087 pp 0.00% +0.001 pp USD26.31 +31.4% 23 qtrs
13 POINT72 ASSET MANAGEMENT, L.P. 1.84M -2.0M (-51.7%) 63.77M -40.1M (-38.6%) 2.06% -2.256 pp 0.07% -0.102 pp USD20.89 +65.5% 4 qtrs
14 GOLDMAN SACHS GROUP INC 1.77M +537.8K (+43.6%) 61.22M +27.7M (+82.5%) 1.98% +0.581 pp 0.01% +0.003 pp USD28.54 +21.1% 27 qtrs
15 PRICE T ROWE ASSOCIATES INC /MD/ 1.45M +339.4K (+30.6%) 50.10M +19.9M (+65.9%) 1.64% +0.383 pp 0.01% +0.002 pp USD29.28 +18.1% 21 qtrs
16 GSK PLC 1.33M +1.3M (+100.0%) 46.09M +46.1M (+100.0%) 1.49% +1.487 pp 5.77% +5.769 pp USD34.57 +0.0% 1 qtrs NEW
17 MORGAN STANLEY 1.25M -327.9K (-20.8%) 43.30M +294.2K (+0.7%) 1.42% -0.371 pp 0.00% +0.000 pp USD26.58 +30.1% 25 qtrs
18 UBS GROUP AG 1.09M +29.1K (+2.7%) 37.53M +8.8M (+30.5%) 1.23% +0.033 pp 0.01% +0.002 pp USD26.10 +32.5% 26 qtrs
19 CANDRIAM S.C.A. 1.03M +18.4K (+1.8%) 35.66M +8.1M (+29.4%) 1.15% +0.005 pp 0.18% +0.033 pp USD28.38 +21.8% 14 qtrs
20 ENSIGN PEAK ADVISORS, INC 979.1K +225.9K (+30.0%) 33.85M +13.4M (+65.2%) 1.09% +0.241 pp 0.06% +0.026 pp USD26.45 +30.7% 22 qtrs
21 CITADEL ADVISORS LLC 959.4K -357.6K (-27.2%) 33.16M -2.7M (-7.5%) 1.08% -0.404 pp 0.01% -0.001 pp USD25.24 +37.0% 16 qtrs
22 DIMENSIONAL FUND ADVISORS LP 938.9K +441.8K (+88.9%) 32.46M +18.9M (+140.0%) 1.05% +0.485 pp 0.01% +0.004 pp USD29.54 +17.0% 18 qtrs
23 BANK OF AMERICA CORP /DE/ 903.0K -13.1K (-1.4%) 31.22M +6.3M (+25.2%) 1.02% -0.015 pp 0.00% +0.001 pp USD27.14 +27.4% 24 qtrs
24 FISHER ASSET MANAGEMENT, LLC 889.6K +27.4K (+3.2%) 30.75M +7.3M (+31.1%) 0.99% +0.018 pp 0.01% +0.002 pp USD33.39 +3.5% 11 qtrs
25 SOFINNOVA INVESTMENTS, INC. 885.1K -37.6K (-4.1%) 30.60M +5.5M (+21.9%) 0.99% -0.056 pp 1.32% -0.054 pp USD21.81 +58.5% 14 qtrs
26 REDMILE GROUP, LLC 742.0K +— (+0.0%) 25.65M +5.5M (+27.0%) 0.83% -0.011 pp 1.89% -0.075 pp USD32.09 +7.7% 9 qtrs
27 PICTET ASSET MANAGEMENT HOLDING SA 734.3K -298.7K (-28.9%) 25.39M -2.7M (-9.7%) 0.82% -0.349 pp 0.02% -0.002 pp USD36.20 -4.5% 9 qtrs
28 FIRST TURN MANAGEMENT, LLC 723.7K +723.7K (+100.0%) 25.02M +25.0M (+100.0%) 0.81% +0.807 pp 2.86% +2.858 pp USD34.57 +0.0% 1 qtrs NEW
29 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 714.6K -905.0 (-0.1%) 24.70M +5.2M (+26.9%) 0.80% -0.012 pp 0.00% +0.001 pp USD28.52 +21.2% 23 qtrs
30 BNP PARIBAS ASSET MANAGEMENT HOLDING S.A. 697.9K +289.5K (+70.9%) 24.13M +13.0M (+117.1%) 0.78% +0.317 pp 0.03% -0.001 pp USD30.26 +14.2% 3 qtrs
31 NORTHERN TRUST CORP 675.1K -34.7K (-4.9%) 23.34M +4.0M (+20.8%) 0.75% -0.049 pp 0.00% +0.001 pp USD23.48 +47.2% 23 qtrs
32 BALYASNY ASSET MANAGEMENT L.P. 596.5K +216.2K (+56.8%) 20.62M +10.3M (+99.3%) 0.67% +0.235 pp 0.03% +0.013 pp USD29.48 +17.3% 6 qtrs
33 ABRDN PLC 560.6K +2.6K (+0.5%) 19.38M +4.2M (+27.6%) 0.63% -0.006 pp 0.03% +0.006 pp USD26.30 +31.4% 6 qtrs
34 NEW YORK STATE COMMON RETIREMENT FUND 508.3K +19.4K (+4.0%) 17.57M +4.3M (+32.1%) 0.57% +0.014 pp 0.02% +0.006 pp USD34.80 -0.7% 23 qtrs
35 DAFNA CAPITAL MANAGEMENT LLC 506.7K -33.2K (-6.1%) 17.52M +2.8M (+19.2%) 0.57% -0.045 pp 4.07% +0.440 pp USD18.58 +86.1% 22 qtrs
36 QUBE RESEARCH & TECHNOLOGIES LTD 467.9K +204.2K (+77.4%) 16.17M +9.0M (+125.4%) 0.52% +0.224 pp 0.02% +0.009 pp USD31.21 +10.8% 12 qtrs
37 IRON TRIANGLE PARTNERS LP 467.5K +197.5K (+73.1%) 16.16M +8.8M (+120.0%) 0.52% +0.216 pp 1.85% +0.803 pp USD30.32 +14.0% 2 qtrs
38 LOGOS GLOBAL MANAGEMENT LP 450.0K +— (+0.0%) 15.56M +3.3M (+27.0%) 0.50% -0.007 pp 0.94% -0.158 pp USD27.21 +27.0% 2 qtrs
39 CAPTION MANAGEMENT, LLC 450.0K +450.0K (+100.0%) 15.56M +15.6M (+100.0%) 0.51% +0.509 pp 0.11% +0.107 pp USD34.57 +0.0% 1 qtrs NEW
40 TANG CAPITAL MANAGEMENT LLC 450.0K +50.0K (+12.5%) 15.56M +4.7M (+42.9%) 0.51% +0.056 pp 0.77% +0.350 pp USD28.03 +23.3% 2 qtrs
41 NUVEEN, LLC 374.0K +165.2K (+79.2%) 12.93M +7.2M (+127.6%) 0.42% +0.187 pp 0.00% +0.002 pp USD24.42 +41.6% 4 qtrs
42 DEUTSCHE BANK AG\ 368.5K -37.2K (-9.2%) 12.74M +1.7M (+15.4%) 0.41% -0.048 pp 0.00% +0.000 pp USD33.09 +4.5% 23 qtrs
43 JPMORGAN CHASE & CO 299.9K +125.6K (+72.1%) 10.37M +5.6M (+118.6%) 0.33% +0.138 pp 0.00% +0.000 pp USD27.74 +24.6% 23 qtrs
44 EVENTIDE ASSET MANAGEMENT, LLC 284.1K -341.6K (-54.6%) 9.82M -7.2M (-42.3%) 0.32% -0.390 pp 0.15% -0.127 pp USD26.26 +31.6% 10 qtrs
45 GENERAL AMERICAN INVESTORS CO INC 280.3K +— (+0.0%) 9.69M +2.1M (+27.0%) 0.31% -0.004 pp 0.55% +0.105 pp USD23.07 +49.8% 6 qtrs
46 ENVESTNET ASSET MANAGEMENT INC 277.6K -21.5K (-7.2%) 9.60M +1.5M (+17.9%) 0.31% -0.024 pp 0.00% +0.001 pp USD31.40 +10.1% 8 qtrs
47 WELLS FARGO & COMPANY/MN 256.1K +13.1K (+5.4%) 8.85M +2.2M (+33.9%) 0.29% +0.015 pp 0.00% +0.000 pp USD32.16 +7.5% 23 qtrs
48 RHENMAN & PARTNERS ASSET MANAGEMENT AB 250.0K +250.0K (+100.0%) 8.64M +8.6M (+100.0%) 0.28% +0.279 pp 0.81% +0.808 pp USD34.57 +0.0% 1 qtrs NEW
49 BANK OF NEW YORK MELLON CORP 244.0K -4.9K (-2.0%) 8.44M +1.7M (+24.6%) 0.27% -0.009 pp 0.00% +0.000 pp USD25.69 +34.6% 23 qtrs
50 FRANKLIN RESOURCES INC 240.2K +4.8K (+2.0%) 8.30M +1.9M (+29.6%) 0.27% +0.002 pp 0.00% +0.000 pp USD27.36 +26.4% 2 qtrs
51 INVESCO LTD. 238.3K +114.1K (+91.9%) 8.24M +4.9M (+143.8%) 0.27% +0.129 pp 0.00% +0.001 pp USD30.27 +14.2% 18 qtrs
52 BARCLAYS PLC 235.9K +54.7K (+30.2%) 8.15M +2.4M (+42.1%) 0.27% +0.062 pp 0.00% +0.001 pp USD28.03 +23.3% 23 qtrs
53 WCM INVESTMENT MANAGEMENT, LLC 219.3K -14.1K (-6.1%) 7.57M +1.2M (+19.2%) 0.24% -0.019 pp 0.02% +0.002 pp USD25.62 +34.9% 5 qtrs
54 MILLENNIUM MANAGEMENT LLC 208.5K +71.0K (+51.6%) 7.21M +3.5M (+92.6%) 0.24% +0.080 pp 0.00% +0.001 pp USD27.77 +24.5% 8 qtrs
55 AMERICAN CENTURY COMPANIES INC 204.4K +17.7K (+9.5%) 7.07M +2.0M (+39.1%) 0.23% +0.017 pp 0.00% +0.001 pp USD24.10 +43.4% 4 qtrs
56 SUSQUEHANNA PORTFOLIO STRATEGIES, LLC 202.4K +39.2K (+24.0%) 7.00M +2.6M (+57.5%) 0.23% +0.044 pp 0.11% +0.038 pp USD28.63 +20.7% 2 qtrs
57 WOODLINE PARTNERS LP 201.7K +— (+0.0%) 6.97M +1.5M (+27.0%) 0.23% +0.000 pp 0.03% +0.001 pp USD30.29 +14.1% 11 qtrs
58 NICHOLAS INVESTMENT PARTNERS, LP 192.4K +192.4K (+100.0%) 6.65M +6.7M (+100.0%) 0.21% +0.215 pp 0.48% +0.485 pp USD34.57 +0.0% 1 qtrs NEW
59 ALYESKA INVESTMENT GROUP, L.P. 192.3K +192.3K (+100.0%) 6.65M +6.6M (+100.0%) 0.21% +0.215 pp 0.02% +0.019 pp USD34.57 +0.0% 1 qtrs NEW
60 UBS ASSET MANAGEMENT AMERICAS INC 174.1K -27.3K (-13.6%) 6.02M +538.2K (+9.8%) 0.19% -0.034 pp 0.00% +0.000 pp USD29.37 +17.7% 10 qtrs
61 SCHRODER INVESTMENT MANAGEMENT GROUP 171.3K -34.5K (-16.8%) 5.91M +316.1K (+5.6%) 0.19% -0.042 pp 0.00% +0.000 pp USD33.54 +3.1% 8 qtrs
62 ROYAL BANK OF CANADA 165.3K -244.3K (-59.6%) 5.72M -5.4M (-48.7%) 0.19% -0.276 pp 0.00% -0.001 pp USD24.57 +40.7% 21 qtrs
63 VICTORY CAPITAL MANAGEMENT INC 163.4K -65.5K (-28.6%) 5.65M -579.1K (-9.3%) 0.18% -0.077 pp 0.00% -0.001 pp USD27.57 +25.4% 9 qtrs
64 STEMPOINT CAPITAL LP 161.7K -210.2K (-56.5%) 5.59M -4.5M (-44.8%) 0.18% -0.238 pp 0.96% -1.069 pp USD23.61 +46.4% 8 qtrs
65 SWISS NATIONAL BANK 155.6K +2.8K (+1.8%) 5.38M +1.2M (+29.4%) 0.17% +0.001 pp 0.00% +0.001 pp USD27.38 +26.3% 17 qtrs
66 GREAT LAKES ADVISORS, LLC 150.0K +150.0K (+100.0%) 5.19M +5.2M (+100.0%) 0.17% +0.170 pp 0.04% +0.042 pp USD34.57 +0.0% 1 qtrs NEW
67 CREATIVE PLANNING 136.1K +3.2K (+2.4%) 4.70M +1.1M (+30.1%) 0.15% +0.002 pp 0.00% +0.001 pp USD21.41 +61.5% 9 qtrs
68 CITIGROUP INC 127.1K +86.3K (+211.4%) 4.39M +3.3M (+295.6%) 0.14% +0.096 pp 0.00% +0.001 pp USD32.05 +7.9% 25 qtrs
69 RAFFERTY ASSET MANAGEMENT, LLC 126.4K +33.2K (+35.7%) 4.37M +1.8M (+72.3%) 0.14% +0.036 pp 0.02% +0.007 pp USD27.35 +26.4% 18 qtrs
70 PLATINUM INVESTMENT MANAGEMENT LTD 120.6K -46.3K (-27.7%) 4.17M -372.5K (-8.2%) 0.13% -0.054 pp 0.96% +0.670 pp USD21.74 +59.0% 22 qtrs
71 TWO SIGMA INVESTMENTS, LP 113.8K +4.1K (+3.8%) 3.94M +950.2K (+31.8%) 0.13% +0.005 pp 0.01% +0.001 pp USD35.88 -3.7% 16 qtrs
72 113.5K +113.5K (+100.0%) 3.92M +3.9M (+100.0%) 0.13% +0.127 pp 0.14% +0.141 pp USD34.57 +0.0% 1 qtrs NEW
73 NEUBERGER BERMAN GROUP LLC 111.3K +111.3K (+100.0%) 3.85M +3.8M (+100.0%) 0.12% +0.124 pp 0.00% +0.003 pp USD34.57 +0.0% 1 qtrs NEW
74 RHUMBLINE ADVISERS 107.6K -17.2K (-13.8%) 3.72M +323.4K (+9.5%) 0.12% -0.020 pp 0.00% +0.000 pp USD23.03 +50.1% 23 qtrs
75 ALLIANCEBERNSTEIN L.P. 97.9K -3.0 (0.0%) 3.38M +720.4K (+27.0%) 0.11% +0.000 pp 0.00% +0.000 pp USD27.79 +24.4% 23 qtrs
76 HEALTHINVEST PARTNERS AB 97.4K +97.4K (+100.0%) 3.37M +3.4M (+100.0%) 0.11% +0.109 pp 1.07% +1.075 pp USD34.57 +0.0% 1 qtrs NEW
77 MML INVESTORS SERVICES, LLC 83.9K +2.6K (+3.2%) 2.90M +687.7K (+31.1%) 0.09% +0.002 pp 0.01% +0.001 pp USD27.44 +26.0% 2 qtrs
78 LEGAL & GENERAL GROUP PLC 83.9K -8.1K (-8.8%) 2.90M +397.6K (+15.9%) 0.09% -0.010 pp 0.00% +0.000 pp USD26.69 +29.5% 23 qtrs
79 Y-INTERCEPT (HONG KONG) LTD 81.0K +81.0K (+100.0%) 2.80M +2.8M (+100.0%) 0.09% +0.090 pp 0.06% +0.063 pp USD34.57 +0.0% 1 qtrs NEW
80 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 75.9K +1.4K (+1.8%) 2.63M +596.3K (+29.4%) 0.08% +0.000 pp 0.00% +0.001 pp USD24.09 +43.5% 23 qtrs
81 SIO CAPITAL MANAGEMENT, LLC 75.7K -48.5K (-39.0%) 2.62M -762.3K (-22.6%) 0.09% -0.055 pp 0.41% -0.444 pp USD31.57 +9.5% 14 qtrs
82 JANE STREET GROUP, LLC 74.4K +64.0K (+615.4%) 2.57M +2.3M (+808.9%) 0.08% +0.071 pp 0.00% +0.000 pp USD33.54 +3.1% 2 qtrs
83 ASSETMARK, INC 71.9K -4.3K (-5.6%) 2.49M +412.3K (+19.9%) 0.08% -0.006 pp 0.01% +0.001 pp USD32.53 +6.3% 8 qtrs
84 ALPS ADVISORS INC 71.8K +29.6K (+70.3%) 2.48M +1.3M (+116.4%) 0.08% +0.032 pp 0.01% +0.008 pp USD30.84 +12.1% 11 qtrs
85 NEOS INVESTMENT MANAGEMENT LLC 71.2K -3.1K (-4.2%) 2.46M +439.8K (+21.8%) 0.08% -0.004 pp 0.01% -0.001 pp USD21.65 +59.7% 7 qtrs
86 TEMA ETFS LLC 70.1K -4.1K (-5.6%) 2.42M +403.5K (+20.0%) 0.08% -0.006 pp 0.19% +0.020 pp USD19.91 +73.6% 5 qtrs
87 MANUFACTURERS LIFE INSURANCE COMPANY, THE 69.9K +3.4K (+5.1%) 2.41M +605.5K (+33.5%) 0.08% +0.003 pp 0.00% +0.001 pp USD28.10 +23.0% 21 qtrs
88 SEI INVESTMENTS CO 68.7K +23.3K (+51.3%) 2.38M +1.1M (+92.2%) 0.08% +0.025 pp 0.00% +0.001 pp USD25.27 +36.8% 4 qtrs
89 AQR CAPITAL MANAGEMENT LLC 68.2K +46.0K (+206.7%) 2.36M +1.8M (+289.7%) 0.08% +0.051 pp 0.00% +0.001 pp USD30.32 +14.0% 11 qtrs
90 DEKABANK DEUTSCHE GIROZENTRALE 50.0K +— (+0.0%) 2.35M +1.0M (+74.2%) 0.06% +0.000 pp 0.00% +0.002 pp USD21.35 +61.9% 21 qtrs
91 XTX TOPCO LTD 66.2K +66.2K (+100.0%) 2.29M +2.3M (+100.0%) 0.07% +0.075 pp 0.06% +0.060 pp USD34.57 +0.0% 1 qtrs NEW
92 BOOTHBAY FUND MANAGEMENT, LLC 60.3K -14.5K (-19.4%) 2.08M +48.7K (+2.4%) 0.07% -0.017 pp 0.03% +0.002 pp USD23.00 +50.3% 3 qtrs
93 BRINKER CAPITAL INVESTMENTS, LLC 58.4K +4.0K (+7.3%) 2.02M +537.6K (+36.3%) 0.07% +0.005 pp 0.01% +0.003 pp USD27.92 +23.8% 8 qtrs
94 LIDO ADVISORS, LLC 55.5K +55.5K (+100.0%) 1.91M +1.9M (+100.0%) 0.06% +0.062 pp 0.01% +0.006 pp USD34.57 +0.0% 1 qtrs NEW
95 SUSQUEHANNA INTERNATIONAL GROUP, LLP 53.2K +21.4K (+67.3%) 1.84M +973.8K (+112.5%) 0.06% +0.024 pp 0.00% +0.000 pp USD30.17 +14.6% 2 qtrs
Ownership breakdown by holder

ETF Ownership

Top ETFs holding this stock Held by 116 ETFs in our universe
# ETF Weight Est. AUM exposure TER
1 iShares Genomics Immunology and Healthcare ETF IDNA 3.38% 6.62M 0.47%
2 Tema Oncology ETF CANC 2.61% 3.72M 0.75%
3 ALPS Medical Breakthroughs ETF SBIO 1.66% 3.53M 0.50%
4 Global X - S&P Biotech ETF CURE.AX 0.79% 285.0K 0.45%
5 State Street SPDR S&P Biotech ETF XBI 0.79% 85.84M 0.35%
6 Virtus Biotech Clinical Trials ETF BBC 0.79% 452.2K 0.65%
7 First Trust Innovation Leaders ETF ILDR 0.57% 1.73M 0.75%
8 Invesco Russell 2000 Dynamic Multifactor ETF OMFS 0.47% 1.32M 0.39%
9 iShares Healthcare Innovation UCITS ETF HEAL.L 0.37% 4.22M 0.40%
10 iShares Ageing Population UCITS ETF AGED.L 0.28% 2.45M 0.40%

Insider Activity

Insider Activity — Latest Quarter
Ratio by transactions
0.00
Bearish
Buys
8
Sells
0
Shares acquired
1.55M
Shares disposed
Cash buys
1.00
Cash sales
Net activity
+1,550,000
Insider buys vs sells (history) From To
Recent insider transactions From To
Date Person Role Transaction A/D Security Shares Price Value Owned after D/I Filing
2026-03-02 Stein Jeffrey Director P-Purchase A Common Stock 50,000 32.96 1.65M 54,281 D
2026-01-30 WHITE MICHAEL ANTHONY Officer A-Award A Stock Option (right to buy) 190,000 32.19 6.12M 190,000 D
2026-01-30 Snyder Douglas B. Officer A-Award A Stock Option (right to buy) 130,000 32.19 4.18M 130,000 D
2026-01-30 Ruiz Briseno Andres Officer A-Award A Stock Option (right to buy) 80,000 32.19 2.58M 80,000 D
2026-01-30 Hata Yujiro S Director / Officer A-Award A Stock Option (right to buy) 600,000 32.19 19.31M 600,000 D
2026-01-30 DORMAN STUART Officer A-Award A Stock Option (right to buy) 155,000 32.19 4.99M 155,000 D
2026-01-30 Bleharski Joshua Officer A-Award A Stock Option (right to buy) 170,000 32.19 5.47M 170,000 D
2026-01-30 Beaupre Darrin Officer A-Award A Stock Option (right to buy) 175,000 32.19 5.63M 175,000 D
2025-11-28 Snyder Douglas B. Officer A-Award A Common Stock 1,041 16.91 17.6K 2,080 D
2025-11-28 Ruiz Briseno Andres Officer A-Award A Common Stock 1,253 16.91 21.2K 26,466 D
2025-06-27 Bleharski Joshua Officer Stock Option (right to buy) 250,000 20.05 5.01M 0 D
2025-06-24 YARNO WENDY L Director A-Award A Stock Option (right to buy) 20,000 21.78 435.6K 20,000 D
2025-06-24 Stein Jeffrey Director A-Award A Stock Option (right to buy) 20,000 21.78 435.6K 20,000 D
2025-06-24 ROSEN TERRY J Director A-Award A Stock Option (right to buy) 20,000 21.78 435.6K 20,000 D
2025-06-24 Morrison Scott W Director A-Award A Stock Option (right to buy) 20,000 21.78 435.6K 20,000 D
2025-06-24 MACKEY CATHERINE J Director A-Award A Stock Option (right to buy) 20,000 21.78 435.6K 20,000 D
2025-06-24 Hampton Malcolm Garret Director A-Award A Stock Option (right to buy) 20,000 21.78 435.6K 20,000 D
2025-05-30 Snyder Douglas B. Officer A-Award A Common Stock 1,039 16.91 17.6K 1,039 D
2025-02-27 WHITE MICHAEL ANTHONY Officer A-Award A Stock Option (right to buy) 185,000 20.24 3.74M 185,000 D
2025-02-27 Snyder Douglas B. Officer A-Award A Stock Option (right to buy) 33,000 20.24 667.9K 33,000 D
2025-02-27 Ruiz Briseno Andres Officer A-Award A Stock Option (right to buy) 75,000 20.24 1.52M 75,000 D
2025-02-27 Hata Yujiro S Director / Officer A-Award A Stock Option (right to buy) 600,000 20.24 12.14M 600,000 D
2025-02-27 DORMAN STUART Officer A-Award A Stock Option (right to buy) 15,000 20.24 303.6K 15,000 D
2025-02-27 Beaupre Darrin Officer A-Award A Stock Option (right to buy) 185,000 20.24 3.74M 185,000 D
2025-02-18 Hata Yujiro S Director / Officer M-Exempt A Common Stock 12,808 19.52 250.0K 690,695 D
2024-12-11 DORMAN STUART Officer Stock Option (Right to Buy) 170,000 27.45 4.67M 0 D
2024-11-29 Ruiz Briseno Andres Officer A-Award A Common Stock 682 23.26 15.9K 25,213 D
2024-09-26 Snyder Douglas B. Officer A-Award A Stock Option (Right to Buy) 140,000 30.50 4.27M 140,000 D
2024-09-18 Snyder Douglas B. 0 0.00 0
2024-06-27 Throne Jason Officer M-Exempt A Common Stock 47,060 7.01 329.9K 63,484
2024-05-31 YARNO WENDY L Director A-Award A Stock Option (right to buy) 16,200 36.55 592.1K 16,200
2024-05-31 Stein Jeffrey Director A-Award A Stock Option (right to buy) 16,200 36.55 592.1K 16,200
2024-05-31 ROSEN TERRY J Director A-Award A Stock Option (right to buy) 16,200 36.55 592.1K 16,200
2024-05-31 Morrison Scott W Director A-Award A Stock Option (right to buy) 16,200 36.55 592.1K 16,200
2024-05-31 MACKEY CATHERINE J Director A-Award A Stock Option (right to buy) 16,200 36.55 592.1K 16,200
2024-05-31 Kelley Susan L. Director A-Award A Stock Option (right to buy) 16,200 36.55 592.1K 16,200
2024-05-31 Hampton Malcolm Garret Director A-Award A Stock Option (right to buy) 16,200 36.55 592.1K 16,200
2024-05-29 WHITE MICHAEL ANTHONY Officer M-Exempt D Stock Option (right to buy) 28,500 12.86 366.5K 64,000
2024-05-16 Hata Yujiro S Director / Officer M-Exempt A Common Stock 34,433 4.31 148.4K 712,320
2024-05-15 Hata Yujiro S Director / Officer S-Sale D Common Stock 53,592 42.57 2.28M 708,151
2024-05-14 Hata Yujiro S Director / Officer S-Sale D Common Stock 54,408 41.60 2.26M 680,190
2024-03-01 WHITE MICHAEL ANTHONY Officer A-Award A Stock Option (right to buy) 140,000 46.22 6.47M 140,000
2024-03-01 Throne Jason Officer A-Award A Stock Option (right to buy) 125,500 46.22 5.80M 125,500
2024-03-01 Ruiz Briseno Andres Officer A-Award A Stock Option (right to buy) 85,000 46.22 3.93M 85,000
2024-03-01 Hata Yujiro S Director / Officer A-Award A Stock Option (right to buy) 480,000 46.22 22.19M 480,000
2024-03-01 Beaupre Darrin Officer A-Award A Stock Option (right to buy) 160,000 46.22 7.40M 160,000
2024-02-09 Ruiz Briseno Andres Officer S-Sale D Common Stock 2,000 46.02 92.0K 24,531
2024-02-09 Hata Yujiro S Director / Officer M-Exempt A Common Stock 23,557 4.31 101.5K 701,444
2024-02-08 Hata Yujiro S Director / Officer M-Exempt A Common Stock 75,815 4.31 326.8K 753,702
2024-02-01 Hata Yujiro S Director / Officer M-Exempt D Stock Option (right to buy) 628 4.31 2.7K 323,826
2024-01-22 Ruiz Briseno Andres Officer S-Sale D Common Stock 2,000 42.03 84.1K 26,531
2024-01-16 Hata Yujiro S Director / Officer M-Exempt A Common Stock 62,739 4.31 270.4K 740,626
2024-01-12 Ruiz Briseno Andres Officer S-Sale D Common Stock 2,000 38.01 76.0K 28,531
2024-01-12 Hata Yujiro S Director / Officer M-Exempt A Common Stock 12,261 4.31 52.8K 690,148
2023-12-18 Throne Jason Officer M-Exempt D Stock Option (Right to Buy) 10,000 7.01 70.1K 48,420
2023-12-15 Throne Jason Officer S-Sale D Common Stock 10,000 35.04 350.4K 0
2023-12-15 Hata Yujiro S Director / Officer M-Exempt A Common Stock 75,000 4.31 323.3K 752,887
2023-12-14 Ruiz Briseno Andres Officer S-Sale D Common Stock 1,672 34.00 56.8K 30,859
2023-11-03 Throne Jason Officer M-Exempt D Stock Option (Right to Buy) 5,163 12.86 66.4K 48,750
2023-09-12 Throne Jason Officer S-Sale D Common Stock 500 30.01 15.0K 0
2023-09-05 Throne Jason Officer M-Exempt D Stock Option (Right to Buy) 1,737 12.86 22.3K 54,913
2023-09-01 Throne Jason Officer M-Exempt A Common Stock 2,100 12.86 27.0K 2,100
2023-09-01 Ruiz Briseno Andres Officer S-Sale D Common Stock 2,000 30.01 60.0K 32,531
2023-08-29 Stone Paul A. Officer S-Sale D Common Stock 5,000 28.87 144.4K 9,303
2023-08-21 Stone Paul A. Officer S-Sale D Common Stock 978 26.40 25.8K 14,303
2023-08-18 Stone Paul A. Officer S-Sale D Common Stock 3,822 26.38 100.8K 15,281
2023-08-16 Stone Paul A. Officer S-Sale D Common Stock 100 26.45 2.6K 19,203
2023-08-09 Throne Jason Officer M-Exempt A Common Stock 5,000 13.34 66.7K 5,000
2023-08-09 Stone Paul A. Officer S-Sale D Common Stock 2,500 25.05 62.6K 19,303
2023-07-10 Throne Jason Officer M-Exempt D Stock Option (Right to Buy) 5,000 12.86 64.3K 58,750
2023-07-01 Ruiz Briseno Andres Officer D Common Stock 0 0.00 34,531
2023-06-07 YARNO WENDY L Director A-Award A Stock Option (right to buy) 16,200 25.40 411.5K 16,200
2023-06-07 Stein Jeffrey Director A-Award A Stock Option (right to buy) 16,200 25.40 411.5K 16,200
2023-06-07 SHANNON TIMOTHY M Director A-Award A Stock Option (right to buy) 16,200 25.40 411.5K 16,200
2023-06-07 ROSEN TERRY J Director A-Award A Stock Option (right to buy) 16,200 25.40 411.5K 16,200
2023-06-07 Morrison Scott W Director A-Award A Stock Option (right to buy) 16,200 25.40 411.5K 16,200
2023-06-07 MACKEY CATHERINE J Director A-Award A Stock Option (right to buy) 16,200 25.40 411.5K 16,200
2023-06-07 Kelley Susan L. Director A-Award A Stock Option (right to buy) 16,200 25.40 411.5K 16,200
2023-06-07 Hampton Malcolm Garret Director A-Award A Stock Option (right to buy) 16,200 25.40 411.5K 16,200
2023-06-01 Throne Jason Officer M-Exempt D Stock Option (Right to Buy) 3,553 7.01 24.9K 62,905
2023-05-31 Throne Jason Officer M-Exempt D Stock Option (Right to Buy) 432 7.01 3.0K 66,458
2023-05-22 Throne Jason Officer S-Sale D Common Stock 500 23.00 11.5K 0
2023-04-13 Stone Paul A. Officer M-Exempt A Common Stock 8,000 4.62 37.0K 21,803
2023-04-12 Hata Yujiro S Director / Officer M-Exempt A Common Stock 11,601 4.31 50.0K 677,887
2023-02-24 WHITE MICHAEL ANTHONY Officer A-Award A Stock Option (right to buy) 165,000 17.04 2.81M 165,000
2023-02-24 Throne Jason Officer A-Award A Stock Option (right to buy) 100,000 17.04 1.70M 100,000
2023-02-24 Stone Paul A. Officer A-Award A Stock Option (right to buy) 140,000 17.04 2.39M 140,000
2023-02-24 Hata Yujiro S Director / Officer A-Award A Stock Option (right to buy) 400,000 17.04 6.82M 400,000
2023-02-24 Beaupre Darrin Officer A-Award A Stock Option (right to buy) 90,000 17.04 1.53M 90,000
2022-12-09 Beaupre Darrin Officer D Stock Option (right to buy) 180,000 17.48 3.15M
2022-06-09 YARNO WENDY L Director A-Award A Stock Option (right to buy) 11,000 12.29 135.2K 11,000
2022-06-09 Stein Jeffrey Director A-Award A Stock Option (right to buy) 11,000 0.00 11,000
2022-06-09 SHANNON TIMOTHY M Director A-Award A Stock Option (right to buy) 11,000 0.00 11,000
2022-06-09 ROSEN TERRY J Director A-Award A Stock Option (right to buy) 11,000 0.00 11,000
2022-06-09 Morrison Scott W Director A-Award A Stock Option (Right to Buy) 11,000 0.00 11,000
2022-06-09 Kelley Susan L. Director A-Award A Stock Option (right to buy) 11,000 0.00 11,000
2022-06-09 Hampton Malcolm Garret Director A-Award A Stock Option (right to buy) 11,000 0.00 11,000
2022-04-05 MACKEY CATHERINE J Director A-Award A Stock Option (Right to Buy) 22,000 11.80 259.6K 22,000
2022-03-01 WHITE MICHAEL ANTHONY Officer A-Award A Stock Option (right to buy) 92,500 0.00 92,500
2022-03-01 Throne Jason Officer A-Award D Stock Option (Right to Buy) 63,750 12.86 819.8K 63,750
2022-03-01 Stone Paul A. Officer A-Award A Stock Option (right to buy) 92,500 0.00 92,500
2022-03-01 Hata Yujiro S Director / Officer A-Award A Stock Option (right to buy) 260,000 12.86 3.34M 260,000
2021-10-25 WHITE MICHAEL ANTHONY Officer 0 0.00 0
2021-10-04 Dillon Michael P. Officer M-Exempt A Common Stock 1,500 11.08 16.6K 80,289
2021-09-08 Dillon Michael P. Officer M-Exempt A Common Stock 4,313 11.08 47.8K 90,173
2021-09-07 Stone Paul A. Officer S-Sale D Common Stock 2,500 27.42 68.5K 12,944
2021-09-07 Dillon Michael P. Officer M-Exempt D Stock Option (Right to Buy) 116 4.31 499.96 66,119
2021-09-02 Dillon Michael P. Officer S-Sale D Common Stock 10,000 25.09 250.9K 78,789
2021-08-09 Dillon Michael P. Officer M-Exempt A Common Stock 1,500 4.31 6.5K 100,289
2021-07-27 Throne Jason Officer S-Sale D Common Stock 10,000 25.17 251.7K 0
2021-07-27 Dillon Michael P. Officer M-Exempt D Stock Option (right to buy) 5,000 6.92 34.6K 39,500
2021-07-06 Throne Jason Officer S-Sale D Common Stock 6,468 22.16 143.4K 3,532
2021-07-06 Dillon Michael P. Officer M-Exempt A Common Stock 1,500 6.92 10.4K 100,289
2021-06-17 Dillon Michael P. Officer M-Exempt A Common Stock 3,893 6.92 26.9K 102,682
2021-06-16 Dillon Michael P. Officer M-Exempt A Common Stock 1,107 6.92 7.7K 99,896
2021-06-10 YARNO WENDY L Director A-Award A Stock Option (right to buy) 11,000 21.66 238.3K 11,000
2021-06-10 Stein Jeffrey Director A-Award A Stock Option (right to buy) 11,000 21.66 238.3K 11,000
2021-06-10 SHANNON TIMOTHY M Director A-Award A Stock Option (right to buy) 11,000 21.66 238.3K 11,000
2021-06-10 ROSEN TERRY J Director A-Award A Stock Option (right to buy) 11,000 21.66 238.3K 11,000
2021-06-10 Morrison Scott W Director A-Award A Stock Option (right to buy) 11,000 21.66 238.3K 11,000
2021-06-10 Hampton Malcolm Garret Director A-Award A Stock Option (right to buy) 11,000 21.66 238.3K 11,000
2021-06-07 Dillon Michael P. Officer M-Exempt A Common Stock 1,500 6.92 10.4K 100,289
2021-05-28 Stone Paul A. Officer A-Award A Common Stock 859 11.36 9.8K 13,803
2021-05-11 Dillon Michael P. Officer S-Sale D Common Stock 5,000 20.22 101.1K 98,789
2021-02-24 Throne Jason Officer A-Award A Stock Option (right to buy) 52,500 19.52 1.02M 52,500
2021-02-24 Stone Paul A. Officer A-Award A Stock Option (right to buy) 80,000 19.52 1.56M 80,000
2021-02-24 Lackner Mark Officer A-Award A Stock Option (right to buy) 45,000 19.52 878.4K 45,000
2021-02-24 Hata Yujiro S Director / Officer A-Award A Stock Option (right to buy) 195,000 19.52 3.81M 195,000
2021-02-24 Dillon Michael P. Officer A-Award A Stock Option (right to buy) 80,000 19.52 1.56M 80,000
2021-02-12 Kelley Susan L. Director 0 0.00 0
2021-02-10 Lackner Mark Officer M-Exempt D Stock Option (right to buy) 596 6.98 4.2K 33,014
2021-02-09 Lackner Mark Officer S-Sale D Common Stock 1,104 21.05 23.2K 0
2021-02-09 Dillon Michael P. Officer M-Exempt D Stock Option (right to buy) 5,000 6.92 34.6K 57,500
2021-02-08 Lackner Mark Officer M-Exempt D Stock Option (right to buy) 300 6.98 2.1K 34,714
2021-02-02 BVF PARTNERS L P/IL S-Sale D Common Stock, $0.0001 par value 16,850 18.00 303.3K 1,188,131
2021-01-26 Lackner Mark Officer M-Exempt D Stock Option (right to buy) 377 4.62 1.7K 61,760
2020-12-22 Hata Yujiro S Director / Officer M-Exempt D Stock Option (right to buy) 8,000 4.31 34.5K 486,055
2020-12-18 Dillon Michael P. Officer M-Exempt A Common Stock 7,750 4.31 33.4K 98,789
2020-12-11 Stone Paul A. Officer J-Other A Common Stock 444 0.00 15,444
2020-12-04 Throne Jason Officer S-Sale D Common Stock 400 14.66 5.9K 1,579
2020-11-11 5AM Ventures IV, L.P. 10% Owner S-Sale D Common Stock 657,117 13.66 8.98M 2,187,428
2020-07-01 Throne Jason Officer A-Award A Stock Option (Right to Buy) 75,000 13.34 1.00M 75,000
2020-06-30 BVF PARTNERS L P/IL 10% Owner P-Purchase A Common Stock, $0.0001 par value 1,521 13.32 20.3K 1,667,420
2020-06-26 Hampton Malcolm Garret Director A-Award A Stock Option (right to buy) 22,000 14.42 317.2K 22,000
2020-06-22 BVF PARTNERS L P/IL 10% Owner P-Purchase A Common Stock, $0.0001 par value 1,354 13.93 18.9K 237,394
2020-06-19 BVF PARTNERS L P/IL 10% Owner P-Purchase A Common Stock, $0.0001 par value 52,443 14.39 754.6K 1,655,375
2020-06-18 BVF PARTNERS L P/IL 10% Owner D Common Stock, $0.0001 par value 0 0.00 1,602,932
2020-06-17 Stone Paul A. Officer S-Sale D Common Stock 600 19.95 12.0K 15,000
2020-06-17 Lackner Mark Officer S-Sale D Common Stock 373 19.91 7.4K 0
2020-06-16 YARNO WENDY L Director A-Award A Stock Option (right to buy) 11,000 12.84 141.2K 11,000
2020-06-16 Stein Jeffrey Director A-Award A Stock Option (right to buy) 11,000 12.84 141.2K 11,000
2020-06-16 SHANNON TIMOTHY M Director A-Award A Stock Option (right to buy) 11,000 12.84 141.2K 11,000
2020-06-16 ROSEN TERRY J Director A-Award A Stock Option (right to buy) 11,000 12.84 141.2K 11,000
2020-06-16 Morrison Scott W Director A-Award A Stock Option (right to buy) 11,000 12.84 141.2K 11,000
2020-06-16 Lackner Mark Officer S-Sale D Common Stock 6,750 14.93 100.8K 0
2020-06-04 Throne Jason Officer S-Sale D Common Stock 2,205 8.66 19.1K 0
2020-06-02 Lackner Mark Officer S-Sale D Common Stock 408 8.55 3.5K 437
2020-04-15 Hata Yujiro S Director / Officer M-Exempt A Common Stock 47,564 4.31 205.0K 658,286
2020-03-30 Stone Paul A. Officer M-Exempt D Stock Option (right to buy) 5,000 4.62 23.1K 140,932
2020-02-21 Stone Paul A. Officer A-Award A Stock Option (right to buy) 80,000 6.92 553.6K 80,000
2020-02-21 Lackner Mark Officer A-Award A Stock Option (right to buy) 40,000 6.92 276.8K 40,000
2020-02-21 Hata Yujiro S Officer A-Award A Stock Option (right to buy) 215,000 6.92 1.49M 215,000
2020-02-21 Hambleton Julie Officer A-Award A Stock Option (right to buy) 62,500 6.92 432.5K 62,500
2020-02-21 Dillon Michael P. Officer A-Award A Stock Option (right to buy) 62,500 6.92 432.5K 62,500
2019-12-17 YARNO WENDY L Director A-Award A Stock Option (right to buy) 22,000 7.36 161.9K 22,000
2019-10-09 Throne Jason Officer A-Award A Stock Option (right to buy) 75,000 7.01 525.8K 75,000
2019-09-24 Stein Jeffrey Director A-Award A Stock Option (right to buy) 1,250 9.15 11.4K 1,250
2019-09-24 SHANNON TIMOTHY M Director A-Award A Stock Option (right to buy) 11,000 9.15 100.7K 11,000
2019-09-24 ROSEN TERRY J Director A-Award A Stock Option (right to buy) 1,250 9.15 11.4K 1,250
2019-09-24 Morrison Scott W Director A-Award A Stock Option (right to buy) 1,250 9.15 11.4K 1,250
2019-09-24 DIEKMAN JOHN D Director A-Award A Stock Option (right to buy) 11,000 9.15 100.7K 11,000
2019-07-30 Hata Yujiro S Director / Officer M-Exempt A Common Stock 15,000 4.31 64.7K 610,722
2019-07-26 Stone Paul A. Officer M-Exempt D Stock Option (right to buy) 10,000 4.62 46.2K 145,932
2019-07-26 Hager Jeffrey Officer M-Exempt A Common Stock 5,197 4.31 22.4K 127,853
2019-07-10 Hager Jeffrey Officer M-Exempt D Stock Option (right to buy) 7,145 4.31 30.8K 33,275
2019-06-19 Hager Jeffrey Officer M-Exempt A Common Stock 8,628 4.31 37.2K 115,511
2019-05-28 Stone Paul A. Officer C-Conversion D Series B Preferred Stock 24,101 0.00 0
2019-05-28 SHANNON TIMOTHY M Director P-Purchase A Common Stock 400,000 10.00 4.00M 2,660,713
2019-05-28 DIEKMAN JOHN D Director C-Conversion D Series A Preferred Stock 71,745 0.00 0
2019-05-28 CANAAN X L.P. 10% Owner C-Conversion D Series B Preferred Stock 602,549 0.00 0
2019-05-28 Alexandria Venture Investments, LLC 10% Owner C-Conversion D Series B preferred stock 772,499 0.00 0
2019-05-28 5AM Ventures IV, L.P. 10% Owner C-Conversion A Common Stock 578,447 0.00 2,604,545
2019-05-22 Stone Paul A. Officer D Stock Option (right to buy) 155,932 4.62 720.4K 0
2019-05-22 Stein Jeffrey Director D Common Stock 0 0.00 4,281
2019-05-22 Schroeder Thilo Director 0 0.00 0
2019-05-22 SHANNON TIMOTHY M Director I Series A Preferred Stock 1,658,164 0.00 0
2019-05-22 ROSEN TERRY J Director D Common Stock 0 0.00 16,346
2019-05-22 Morrison Scott W Director D Stock Option (right to buy) 16,346 4.62 75.5K 0
2019-05-22 Lackner Mark Officer D Stock Option (right to buy) 39,000 6.98 272.2K 0
2019-05-22 Hata Yujiro S Director / Officer D Common Stock 0 0.00 595,722
2019-05-22 Hambleton Julie Officer D Stock Option (right to buy) 23,400 11.08 259.3K 0
2019-05-22 Hager Jeffrey Officer D Stock Option (right to buy) 17,550 11.08 194.5K 0
2019-05-22 Dillon Michael P. Officer D Common Stock 0 0.00 91,039
2019-05-22 DIEKMAN JOHN D Director I Common Stock 0 0.00 304,200
2019-05-22 CANAAN X L.P. 10% Owner D Series A Preferred Stock 1,658,164 0.00 0
2019-05-22 Alexandria Venture Investments, LLC 10% Owner D Series A preferred stock 307,066 0.00 0
2019-05-22 5AM Ventures IV, L.P. 10% Owner I Common Stock 0 0.00 304,200

Executive team

Top executives
EBIT / Employee
-1.22M
Shares Outstanding
87.81M

Executive compensation

Executive compensation (annual)
# Year Executive Salary Bonus Stock award Option award Incentive Other Total % Stock-
based
Filing
1 2025 Yujiro S. Hata President and Chief Executive Officer 700.0K 8.42M 378.0K 15.8K 9.51M 88.50%
2 2025 Joshua Bleharski, Ph.D. Chief Financial Officer 333.3K 150.0K 3.46M 186.0K 14.0K 4.15M 83.52%
3 2025 Darrin M. Beaupre, M.D., Ph.D. Chief Medical Officer 526.5K 2.60M 196.0K 15.8K 3.33M 77.86%
4 2025 Michael A. White, Ph.D. Chief Scientific Officer 519.0K 2.60M 193.5K 15.8K 3.32M 78.09%
5 2025 Andres Ruiz Briseno Chief Accounting Officer 417.0K 1.05M 168.0K 15.8K 1.65M 63.66%
6 2025 Douglas B. Snyder Chief Legal Officer 440.0K 463.0K 164.0K 64.5K 1.13M 40.92%
7 2024 Yujiro S. Hata President and Chief Executive Officer 646.0K 15.95M 323.0K 15.6K 16.93M 94.18%
8 2024 Darrin M. Beaupre, M.D., Ph.D. Chief Medical Officer 501.5K 5.32M 228.1K 15.6K 6.06M 87.70%
9 2024 Michael A. White, Ph.D. Chief Scientific Officer 489.5K 4.65M 223.3K 15.6K 5.38M 86.46%
10 2024 Jason S. Throne Former Chief Legal Officer 286.2K 4.17M 14.8K 4.47M 93.27%
11 2024 Stuart C. Dorman Chief Commercial Officer 41.7K 100.0K 3.26M 20.0K 150.00 3.42M 95.27%
12 2024 Andres Ruiz Briseno Chief Accounting Officer 382.5K 2.82M 133.9K 15.6K 3.36M 84.15%
13 2023 Yujiro S. Hata President and Chief Executive Officer 598.0K 5.08M 299.0K 15.0K 6.00M 84.79%
14 2023 Michael A. White, Ph.D. Chief Scientific Officer 462.0K 2.10M 184.8K 15.0K 2.76M 76.01%
15 2023 Paul A. Stone. Former Chief Financial Officer 432.0K 1.78M 14.8K 2.23M 79.93%
16 2023 Jason S. Throne Chief Legal Officer 417.0K 1.27M 166.8K 15.0K 1.87M 67.97%
17 2023 Jason S. Throne Former Chief Legal Officer 417.0K 1.27M 166.8K 15.0K 1.87M 67.97%
18 2023 Darrin M. Beaupre, MD., Ph.D. Chief Medical Officer 473.0K 1.14M 189.2K 3.4K 1.81M 63.21%
19 2023 Darrin M. Beaupre, M.D., Ph.D. Chief Medical Officer 473.0K 1.14M 189.2K 3.4K 1.81M 63.21%
20 2023 Andres Ruiz Briseno Chief Accounting Officer 345.0K 927.4K 125.1K 15.0K 1.41M 65.66%
21 2023 Andres Ruiz Briseno Senior Vice President, Head of Finance and Investor Relations 345.0K 927.4K 125.1K 15.0K 1.41M 65.66%
22 2022 Yujiro S. Hata President and Chief Executive Officer 570.0K 2.48M 270.8K 11.0K 3.33M 74.40%
23 2022 Darrin M. Beaupre, M.D., Ph.D. Chief Medical Officer 52.5K 100.0K 2.38M 150.00 2.53M 93.97%
24 2022 Darrin M. Beaupre, MD., Ph.D. Chief Medical Officer 52.5K 100.0K 2.38M 150.00 2.53M 93.97%
25 2022 Michael White, Ph.D. Chief Scientific Officer 440.0K 880.6K 169.8K 4.0K 1.49M 58.93%
26 2022 Michael A. White, Ph.D. Chief Scientific Officer 440.0K 880.6K 169.8K 4.0K 1.49M 58.93%
27 2022 Paul A. Stone. Former Chief Financial Officer 419.0K 880.6K 161.7K 11.0K 1.47M 59.81%
28 2021 Yujiro S. Hata President and Chief Executive Officer 543.6K 3.05M 244.6K 10.5K 3.85M 79.25%
29 2021 Michael White, Ph.D. Senior Vice President and Chief Scientific Officer, Head of Research 80.6K 180.0K 3.32M 375.00 3.58M 92.72%
30 2021 Michael A. White, Ph.D. Chief Scientific Officer 80.6K 180.0K 3.32M 375.00 3.58M 92.72%
31 2021 Michael White, Ph.D. Chief Scientific Officer 80.6K 180.0K 3.32M 375.00 3.58M 92.72%
32 2021 Michael Dillon, Ph.D. Former Senior Vice President and Chief Scientific Officer, Head of Research 385.8K 1.25M 379.1K 2.02M 62.06%
33 2021 Paul A. Stone, J.D. Senior Vice President and Chief Financial Officer 394.0K 1.25M 146.9K 10.5K 1.80M 69.41%
34 2021 Paul A. Stone. Former Chief Financial Officer 394.0K 1.25M 146.9K 10.5K 1.80M 69.41%
35 2020 Yujiro S. Hata President and Chief Executive Officer 509.8K 1.07M 191.2K 10.4K 1.78M 59.99%
36 2020 Jason S. Throne, J.D. Senior Vice President, General Counsel, and Corporate Secretary 332.5K 738.2K 89.5K 3.6K 1.16M 63.43%
37 2020 Paul A. Stone, J.D. Senior Vice President and Chief Financial Officer 374.5K 396.8K 123.6K 10.4K 905.3K 43.84%
38 2020 Michael Dillon, Ph.D. Former Senior Vice President and Chief Scientific Officer, Head of Research 371.0K 310.0K 122.4K 1.8K 805.3K 38.50%
39 2019 Yujiro Hata President and Chief Executive Officer 457.2K 1.40M 154.9K 10.2K 2.02M 69.21%
40 2019 Yujiro S. Hata President and Chief Executive Officer 457.2K 1.40M 154.9K 10.2K 2.02M 69.21%
41 2019 Julie Hambleton, M.D. Senior Vice President and Chief Medical Officer, Head of Development 387.1K 181.0K 108.5K 10.2K 686.7K 26.35%
42 2019 Michael Dillon, Ph.D. Senior Vice President and Chief Scientific Officer, Head of Research 338.9K 226.2K 95.5K 10.2K 670.8K 33.72%
43 2019 Paul A. Stone, J.D. Senior Vice President and Chief Financial Officer 327.3K 181.0K 103.0K 1.8K 613.0K 29.52%
44 2018 Yujiro Hata President and Chief Executive Officer 420.0K 1.69M 147.0K 8.0K 2.26M 74.59%
45 2018 Julie Hambleton, M.D. Senior Vice President and Chief Medical Officer, Head of Development 218.8K 512.2K 65.6K 1.1K 797.6K 64.22%
46 2018 Michael Dillon, Ph.D. Senior Vice President and Chief Scientific Officer, Head of Research 315.0K 244.0K 94.5K 4.5K 658.0K 37.09%
CEO compensation breakdown

Proxy statements

Proxy statements (DEF 14A)
Filing date Form type Filing
2026-04-30 DEFA14A
2026-04-29 DEF 14A
2025-04-30 DEF 14A

Recent SEC filings

Recent SEC filings
Filing date Form type Filing
2026-05-05 S-3ASR
2026-05-05 8-K
2026-05-05 8-K
2026-05-05 424B5
2026-05-05 10-Q
2026-04-30 DEFA14A
2026-04-29 DEF 14A
2026-04-29 ARS
2026-04-13 8-K
2026-04-09 8-K

Executive team

NameTitleCompensationGender
Yujiro S. Hata Founder, President, Chief Executive Officer & Director 1M male
Darrin Beaupre Chief Medical Officer 745.2K
Michael A. White Chief Scientific Officer 728.4K
Joshua Bleharski Chief Financial Officer 551.4K
Andres Ruiz Briseno Chief Accounting Officer 532.0K male
Stuart Dorman Chief Commercial Officer 161.8K male
Jasgit Sachdev Senior Vice President of Late Phase Clinical Development & Strategy
Daniel A. Simon Chief Business Officer male
Mick O'Quigley Senior Vice President of Medical Writing & Project Management male
Paul A. Barsanti Chief Technology Officer
Theodora Ross Chief Development Officer
Douglas Snyder Chief Legal Officer male
ESG Rating
B
BIOTECHNOLOGY
2026
E (Environmental)
60.0 / 56.3
Company / Sector avg.
S (Social)
72.0 / 62.4
Company / Sector avg.
G (Governance)
68.6 / 60.9
Company / Sector avg.
ESG Total
66.9 / 59.9
Company / Sector avg.
ESG Score History BIOTECHNOLOGY
Benchmark vs Sector
Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend history

Earnings history

Earnings reports

Stock splits