Subscribe

4D Molecular Therapeutics, Inc. (FDMT)

USD11.48 -0.22 (-1.88%)
US NASDAQ Healthcare Biotechnology
Address 5858 Horton Street 94608
EmeryVille, CA, US
CEO David H. Kirn
IPO 2020-12-11
CIK 1650648 ISIN US35104E1001

Explore sections of this company profile

Description

4D Molecular Therapeutics, Inc. is a clinical-stage gene therapy company that engineers therapeutic agents by leveraging its proprietary adeno-associated virus (AAV) vector technology. The company's developmental efforts are concentrated across a trio of therapeutic fields: ophthalmology (eye conditions), cardiology (heart ailments), and pulmonology (respiratory disorders). Within its active pipeline, three specific product candidates have advanced into clinical trial phases, all currently undergoing Phase 1/2 clinical assessment: 4D-125 is being evaluated for the treatment of X-linked retinitis pigmentosa. 4D-110 targets choroideremia. 4D-310 is focused on addressing Fabry disease. Beyond these, two Investigational New Drug (IND) candidates are in development: 4D-150, aimed at combating wet age-related macular degeneration, and 4D-710, designed to tackle cystic fibrosis lung disease. To advance its mission, 4D Molecular Therapeutics, Inc. actively engages in research and development partnerships with entities such as uniQure, CRF, Roche, and CFF. The firm commenced operations in 2013 and maintains its headquarters in Emeryville, California.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
Loading outlook…
Loading forecast...
Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
Loading risk profile…
Price Chart
Averages
Trend
Price
Levels
Draw
USD11.48 -0.22 (-1.88%)
Loading historical data…
Volume Profile
Loading…
Liquidity & share structure
Average Volume
864.8K
Beta
2.69
Float Shares
35.26M
Free Float %
67.5%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
-4.17% +13.88% +2.99% +10.59% +0.58% +37.87% +216.21% -41.98% -60.86% -74.47% -74.47%
Rolling Volatility
Loading…
Drawdown
Loading…
Relative Strength
Loading…
Monthly Returns Heatmap
From To
Loading…
Annual Monthly Returns
Loading…
Daily Returns Distribution
vs.
Loading histogram data…

Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Analyst Consensus (14 ratings, all time) Buy
Price Targets & DCF
Current price
11.48
Low 33.00 +187.4%
Consensus 33.00 +187.4%
Median 33.00 +187.4%
High 33.00 +187.4%
Ratings Trend (MoM) 80% Bullish
Rating 2026-05 Change
Strong Buy 1 0
Buy 7 0
Hold 2 0
Sell 0 0
Strong Sell 0 0
Price Target Summary
Period # Analysts Avg Target
Last Month
Last Quarter
Last Year 3
25.33
+120.6%
All Time 15
38.60
+236.2%
Quality scores
Altman Z-Score
3.26
Safe zone
Piotroski F-Score
2 / 9
Weak
MOAT Score
0 / 10
No MOAT
Composite Rating
C+
Overall Score
2 / 5
Medium
DCF Score
2 / 5
Medium
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
3 / 5
Medium
P/E Score
1 / 5
Low
P/Book Score
4 / 5
High
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
    +230,194.6% Q1'26: +21,664.3% (vs Q1'25)
  • EPS growth Biotechnology: +29.7%
    +18.8% Q1'26: -17.4% (vs Q1'25)
  • FCF margin FCF growth · Biotechnology: +16.2%
    -171.7% Q1'26: -2,235.8% (vs Q1'25)
  • EBIT margin Biotechnology: +0.0%
    -187.2% Q1'26: -2,416.1% (vs Q1'25)
  • ROIC Biotechnology: -16.1%
    -128.2% Q1'26: -361.4% (vs Q1'25)
  • Share dilution Biotechnology: -3.4%
    +7.4% Q1'26: +22.1% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    -0.14× Q1'26: -0.07× (vs Q1'25)
Valuation Multiples From To
Price Forecast (3Y) From To
Model
Adjust
P/E
Theoretical Return — If Invested Today

* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.

DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (2.76) × ERP
WACC = 96% × Ke + 4% × Kd (4.0%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Current price: 11.48
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2020
actual
Dec 2021
actual
Dec 2022
actual
Dec 2023
actual
Dec 2024
actual
Dec 2025
actual
Dec 2026
5 Rev. Ana.
5 EPS Ana.
Dec 2027
4 Rev. Ana.
5 EPS Ana.
Dec 2028
6 Rev. Ana.
4 EPS Ana.
Dec 2029
5 Rev. Ana.
2 EPS Ana.
Dec 2030
3 Rev. Ana.
2 EPS Ana.
Revenue
13.61M
est: 15.21M (-10.5%)
18.04M
est: 18.83M (-4.2%)
3.13M
est: 2.63M (+18.8%)
20.72M
est: 20.22M (+2.5%)
37.0K
est: 1.28M (-97.1%)
85.21M
est: 33.54M (+154.1%)
10.21M
67.8K – 20.35M
-69.6% YoY
14.82M
92.9K – 29.55M
+45.2% YoY
41.43M
39.22M – 43.65M
+179.6% YoY
137.08M
884.4K – 273.27M
+230.8% YoY
295.86M
1.91M – 589.82M
+115.8% YoY
EBITDA
-55.22M
est: -15.21M (-263.1%)
-69.81M
est: -18.83M (-270.7%)
-107.63M
est: -2.63M (-3,987.2%)
-108.66M
est: -20.22M (-437.5%)
-181.14M
est: -1.28M (-13,998.4%)
-151.92M
est: -33.54M (-353.0%)
-10.21M
-20.35M – -67.8K
+69.6% YoY
-14.82M
-29.55M – -92.9K
-45.2% YoY
-41.43M
-43.65M – -39.22M
-179.6% YoY
-137.08M
-273.27M – -884.4K
-230.8% YoY
-295.86M
-589.82M – -1.91M
-115.8% YoY
EBIT
-56.66M
est: -15.21M (-272.6%)
-71.33M
est: -18.83M (-278.8%)
-110.03M
est: -2.63M (-4,078.4%)
-112.87M
est: -20.22M (-458.3%)
-187.84M
est: -1.28M (-14,520.3%)
-159.55M
est: -33.54M (-375.7%)
-10.21M
-20.35M – -67.8K
+69.6% YoY
-14.82M
-29.55M – -92.9K
-45.2% YoY
-41.43M
-43.65M – -39.22M
-179.6% YoY
-137.08M
-273.27M – -884.4K
-230.8% YoY
-295.86M
-589.82M – -1.91M
-115.8% YoY
Net Income
-56.69M
est: -142.23M (+60.1%)
-71.32M
est: -150.10M (+52.5%)
-107.49M
est: -111.37M (+3.5%)
-100.84M
est: -109.89M (+8.2%)
-160.87M
est: -165.85M (+3.0%)
-140.11M
est: -140.11M (+0.0%)
-248.81M
-261.95M – -165.44M
-77.6% YoY
-208.46M
-254.55M – -162.37M
+16.2% YoY
-280.98M
-356.68M – -152.44M
-34.8% YoY
-189.14M
-433.44M – 55.16M
+32.7% YoY
-124.26M
-284.76M – 36.24M
+34.3% YoY
SGA
17.24M
est: 3.88B (-99.6%)
28.01M
est: 4.80B (-99.4%)
32.91M
est: 670.97M (-95.1%)
36.49M
est: 5.15B (-99.3%)
46.58M
est: 327.19M (-85.8%)
49.06M
est: 8.54B (-99.4%)
2.60B
17.27M – 5.18B
-69.6% YoY
3.77B
23.66M – 7.52B
+45.2% YoY
10.55B
9.99B – 11.11B
+179.6% YoY
34.91B
225.22M – 69.59B
+230.8% YoY
75.34B
486.09M – 150.20B
+115.8% YoY
EPS
-2.12
est: -2.64 (+19.6%)
-2.46
est: -2.78 (+11.6%)
-3.12
est: -3.17 (+1.7%)
-2.58
est: -2.32 (-11.4%)
-2.98
est: -2.91 (-2.4%)
-2.42
est: -3.26 (+25.7%)
-3.84
-4.52 – -2.86
-17.8% YoY
-3.67
-4.39 – -2.80
+4.3% YoY
-3.68
-6.16 – -2.63
-0.3% YoY
-3.27
-7.48 – 0.95
+11.3% YoY
-2.15
-4.92 – 0.63
+34.3% YoY
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-07 C+ 2/5 2/5 1/5 1/5 3/5 1/5 4/5
2026-05-06 C+ 2/5 2/5 1/5 1/5 3/5 1/5 4/5
2026-05-05 C+ 2/5 2/5 1/5 1/5 3/5 1/5 4/5
2026-05-04 C+ 2/5 2/5 1/5 1/5 3/5 1/5 4/5
2026-05-01 C+ 2/5 2/5 1/5 1/5 3/5 1/5 4/5
2026-04-30 C+ 2/5 2/5 1/5 1/5 3/5 1/5 4/5
2026-04-29 C 2/5 2/5 1/5 1/5 2/5 1/5 4/5
2026-04-28 C 2/5 2/5 1/5 1/5 2/5 1/5 4/5
2026-04-27 C+ 2/5 3/5 1/5 1/5 2/5 1/5 4/5
2026-04-24 C+ 2/5 3/5 1/5 1/5 2/5 1/5 4/5
2026-04-23 C+ 2/5 3/5 1/5 1/5 2/5 1/5 4/5
2026-04-22 C+ 2/5 3/5 1/5 1/5 2/5 1/5 4/5
2026-04-21 C+ 2/5 3/5 1/5 1/5 2/5 1/5 4/5
2026-04-20 C+ 2/5 3/5 1/5 1/5 2/5 1/5 4/5
2026-04-17 C+ 2/5 3/5 1/5 1/5 2/5 1/5 4/5
2026-04-16 C+ 2/5 3/5 1/5 1/5 2/5 1/5 4/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
-26.15M
OE per share TTM
-0.33
Owner's Yield
-3.87%
Maintenance CapEx ratio
Maint CapEx / Avg PPE
122.0%

Ownership Overview

Ownership breakdown
At a glance
Institutional holders
25
Total invested
9.66M
Insider transactions (90d)
0
Beneficial owners (>5%)
39
Beneficial owners (>5%)
# Reporting person Amount owned % of class Sole voting Shared voting Sole dispositive Shared dispositive Type Citizenship Filing date SEC filing
1 BVF Inc. 4.01M 12.40% 4.01M CO Delaware 2022-06-21
2 BVF Partners L.P. 4.01M 12.40% 4.01M IA, PN Delaware 2022-06-21
3 Mark N. Lampert 4.01M 12.40% 4.01M IN Delaware 2022-06-21
4 BVF GP Holdings LLC 3.70M 11.50% 3.70M OO Delaware 2022-06-21
5 GOLDMAN SACHS & CO. LLC 3.59M 6.90% 3.59M 3.59M BD, IA, OO 2024-11-06
6 THE GOLDMAN SACHS GROUP, INC. 3.59M 6.90% 3.59M 3.59M HC, CO 2024-11-06
7 Koh, Bong 2.89M 8.70% 2.89M 2.89M IN United States 2023-05-15
8 Shah, Nimish 2.89M 8.70% 2.89M 2.89M IN United States 2023-05-15
9 VHCP Co-Investment Holdings III, LLC 2.89M 8.70% 2.89M 2.89M OO Delaware 2023-05-15
10 VHCP Management EG, LLC 2.89M 8.70% 2.89M 2.89M OO Delaware 2023-05-15
11 VHCP Management III, LLC 2.89M 8.70% 2.89M 2.89M OO Delaware 2023-05-15
12 Venrock Healthcare Capital Partners EG, L.P. 2.89M 8.70% 2.89M 2.89M PN Delaware 2023-05-15
13 Venrock Healthcare Capital Partners III, L.P. 2.89M 8.70% 2.89M 2.89M PN Delaware 2023-05-15
14 Peter Kolchinsky 2.79M 6.70% 2.79M HC, IN Delaware 2023-06-05
15 RA Capital Healthcare Fund, L.P. 2.79M 6.70% 2.79M PN Delaware 2023-06-05
16 RA Capital Management, L.P. 2.79M 6.70% 2.79M IA, PN Delaware 2023-06-05
17 Rajeev Shah 2.79M 6.70% 2.79M HC, IN Delaware 2023-06-05
18 BVF I GP LLC 2.13M 6.60% 2.13M OO Delaware 2022-06-21
19 Biotechnology Value Fund, L.P. 2.13M 6.60% 2.13M PN Delaware 2022-06-21
20 (1) BlackRock, Inc. 2.09M 6.50% 2.05M 2.09M HC Delaware 2022-02-04
21 David Kirn 2.03M 6.30% 2.03M 2.03M IN United States 2022-02-14
22 10 2.00M 7.50% 2.00M 2.00M IN 2021-02-16
23 David Kroin 1.80M 5.69% 1.80M HC, IN Delaware 2021-11-04
24 Deep Track Biotechnology Master Fund, Ltd. 1.80M 5.69% 1.80M CO Delaware 2021-11-04
25 Deep Track Capital, LP 1.80M 5.69% 1.80M IA, OO Delaware 2021-11-04
26 Pfizer Inc. 1.67M 6.30% 343.6K 1.32M 343.6K CO Delaware 2021-02-16
27 EIN #00-0000000 1.65M 5.10% 1.65M 1.65M IA, HC Jersey, Channel Islands 2022-02-11
28 Abigail P. Johnson 1.59M 7.38% 1.59M IN United States of America 2021-02-08
29 FMR LLC 1.59M 7.38% 227.3K 1.59M HC Delaware 2021-02-08
30 BVF II GP LLC 1.57M 4.90% 1.57M OO Delaware 2022-06-21
31 Biotechnology Value Fund II, L.P. 1.57M 4.90% 1.57M PN Delaware 2022-06-21
32 Ridgeback Capital Investments Ltd.              00-0000000 1.44M 5.40% 1.44M 1.44M OO Cayman Islands 2020-12-23
33 Ridgeback Capital Management LLC              42-1684320 1.44M 5.40% 1.44M 1.44M OO Delaware 2020-12-23
34 Pfizer Ventures (US) LLC 1.32M 5.00% 1.32M OO Delaware 2021-02-16
35 David Schaffer 901.2K 2.80% 901.2K 901.2K IN 2022-02-14
36 Pfizer Inc.      13-5315170 341.7K 1.06% 341.7K CO 2022-02-11
37 Pfizer Ventures (US) LLC    82-5524518 341.7K 1.06% 341.7K OO 2022-02-11
38 BVF Partners OS Ltd. 209.7K 1.00% 209.7K CO Delaware 2022-06-21
39 Biotechnology Value Trading Fund OS LP 209.7K 1.00% 209.7K PN Delaware 2022-06-21

Institutional Activity (13F)

Institutional ownership trend From To
13F snapshot — 2026 Q1
Investors holding
25
-130 vs prev Q
New positions
5
Closed positions
130
Increased
11
Reduced
5
Put/Call ratio
0.00
Calls held
Puts held
Top institutional holders
# Investor Shares / Δ Mkt value / Δ Own% / Δ Weight% / Δ Avg px / Perf. Hold / Status
1 RA CAPITAL MANAGEMENT, L.P. 5.65M +1.1M (+23.9%) 42.40M +2.7M (+6.9%) 10.07% +1.913 pp 0.43% -0.054 pp USD16.81 -55.4% 11 qtrs
2 JANUS HENDERSON GROUP PLC 4.64M +2.9M (+164.4%) 34.73M +19.5M (+127.9%) 8.26% +5.125 pp 0.02% +0.009 pp USD14.58 -48.6% 21 qtrs
3 BVF INC/IL 4.63M +— (+0.0%) 34.72M -5.5M (-13.7%) 8.25% -0.029 pp 1.17% -0.462 pp USD10.84 -30.8% 21 qtrs
4 GOLDMAN SACHS GROUP INC 4.30M +174.5K (+4.2%) 32.27M -3.6M (-10.0%) 7.67% +0.285 pp 0.00% 0.000 pp USD21.83 -65.6% 21 qtrs
5 BLACKROCK, INC. 4.06M +195.7K (+5.1%) 30.49M -3.1M (-9.3%) 7.24% +0.324 pp 0.00% 0.000 pp USD10.60 -29.2% 6 qtrs
6 NOVO HOLDINGS A/S 3.65M +1.7M (+82.5%) 27.38M +10.0M (+57.5%) 6.50% +2.928 pp 2.13% +1.006 pp USD10.80 -30.6% 12 qtrs
7 VANGUARD GROUP INC 3.09M +518.4K (+20.1%) 23.20M +823.6K (+3.7%) 5.51% +0.907 pp 0.00% +0.000 pp USD21.56 -65.2% 21 qtrs
8 STATE STREET CORP 2.69M +1.8M (+197.5%) 20.17M +12.3M (+156.8%) 4.79% +3.175 pp 0.00% +0.000 pp USD12.68 -40.9% 20 qtrs
9 ARMISTICE CAPITAL, LLC 1.94M +840.0K (+76.6%) 14.52M +5.0M (+52.5%) 3.45% +1.490 pp 0.17% +0.032 pp USD8.50 -11.8% 6 qtrs
10 FEDERATED HERMES, INC. 1.61M +14.7K (+0.9%) 12.07M -1.8M (-12.9%) 2.87% +0.016 pp 0.02% -0.004 pp USD3.39 +121.2% 5 qtrs
11 POINT72 ASSET MANAGEMENT, L.P. 1.54M +1.5M (+100.0%) 11.55M +11.5M (+100.0%) 2.74% +2.744 pp 0.01% +0.013 pp USD7.50 +0.0% 1 qtrs NEW
12 ADAGE CAPITAL PARTNERS GP, L.L.C. 1.24M +1.1M (+605.8%) 9.26M +7.7M (+509.2%) 2.20% +1.888 pp 0.01% +0.012 pp USD7.67 -2.2% 2 qtrs
13 GEODE CAPITAL MANAGEMENT, LLC 1.01M +98.5K (+10.8%) 7.59M -348.6K (-4.4%) 1.80% +0.170 pp 0.00% +0.000 pp USD23.00 -67.4% 21 qtrs
14 EVERGREEN QUALITY FUND GP, LTD. 951.5K +951.5K (+100.0%) 7.14M +7.1M (+100.0%) 1.70% +1.695 pp 0.14% +0.141 pp USD7.50 +0.0% 1 qtrs NEW
15 BANK OF AMERICA CORP /DE/ 832.6K +13.3K (+1.6%) 6.24M -875.0K (-12.3%) 1.48% +0.019 pp 0.00% +0.000 pp USD4.59 +63.4% 21 qtrs
16 DEUTSCHE BANK AG\ 704.2K +160.9K (+29.6%) 5.28M +560.0K (+11.9%) 1.25% +0.283 pp 0.00% +0.000 pp USD9.57 -21.6% 20 qtrs
17 MORGAN STANLEY 672.7K -163.2K (-19.5%) 5.05M -2.2M (-30.5%) 1.20% -0.296 pp 0.00% 0.000 pp USD12.29 -39.0% 21 qtrs
18 RENAISSANCE TECHNOLOGIES LLC 512.9K +199.7K (+63.8%) 3.85M +1.1M (+41.3%) 0.91% +0.354 pp 0.01% +0.002 pp USD7.08 +5.9% 4 qtrs
19 PARKMAN HEALTHCARE PARTNERS LLC 503.4K +303.4K (+151.7%) 3.78M +2.0M (+117.2%) 0.90% +0.539 pp 0.36% +0.178 pp USD7.97 -5.9% 2 qtrs
20 ARROWMARK COLORADO HOLDINGS LLC 485.4K -18.7K (-3.7%) 3.64M -740.3K (-16.9%) 0.86% -0.037 pp 0.08% -0.001 pp USD28.48 -73.7% 21 qtrs
21 RAYMOND JAMES FINANCIAL INC 477.5K +6.2K (+1.3%) 3.58M -514.0K (-12.6%) 0.85% +0.008 pp 0.00% 0.000 pp USD4.18 +79.4% 5 qtrs
22 RTW INVESTMENTS, LP 475.7K +475.7K (+100.0%) 3.57M +3.6M (+100.0%) 0.85% +0.848 pp 0.04% +0.036 pp USD7.50 +0.0% 1 qtrs NEW
23 BAKER BROS. ADVISORS LP 475.7K +475.7K (+100.0%) 3.57M +3.6M (+100.0%) 0.85% +0.848 pp 0.02% +0.021 pp USD7.50 +0.0% 1 qtrs NEW
24 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 353.4K +47.5K (+15.5%) 2.65M -7.5K (-0.3%) 0.63% +0.083 pp 0.00% +0.000 pp USD21.43 -65.0% 20 qtrs
25 TWO SIGMA INVESTMENTS, LP 337.5K +64.0K (+23.4%) 2.53M +154.6K (+6.5%) 0.60% +0.112 pp 0.00% +0.000 pp USD6.87 +9.2% 17 qtrs
26 NORTHERN TRUST CORP 313.8K -21.8K (-6.5%) 2.35M -562.6K (-19.3%) 0.56% -0.041 pp 0.00% 0.000 pp USD23.24 -67.7% 20 qtrs
27 ASSENAGON ASSET MANAGEMENT S.A. 296.2K -367.5K (-55.4%) 2.22M -3.5M (-61.5%) 0.53% -0.659 pp 0.00% -0.005 pp USD16.17 -53.6% 8 qtrs
28 DIMENSIONAL FUND ADVISORS LP 294.8K +236.8K (+408.3%) 2.21M +1.7M (+339.2%) 0.53% +0.422 pp 0.00% +0.000 pp USD9.33 -19.6% 12 qtrs
29 JPMORGAN CHASE & CO 279.5K -234.0K (-45.6%) 2.10M -2.4M (-53.0%) 0.50% -0.420 pp 0.00% 0.000 pp USD9.97 -24.8% 20 qtrs
30 TWO SIGMA ADVISERS, LP 275.3K -274.4K (-49.9%) 2.06M -2.7M (-56.8%) 0.49% -0.492 pp 0.00% -0.006 pp USD3.95 +89.9% 6 qtrs
31 BURKEHILL GLOBAL MANAGEMENT, LP 275.0K +275.0K (+100.0%) 2.06M +2.1M (+100.0%) 0.49% +0.490 pp 0.14% +0.136 pp USD7.50 +0.0% 1 qtrs NEW
32 PEAPOD LANE CAPITAL LLC 268.0K -54.1K (-16.8%) 2.01M -788.5K (-28.2%) 0.48% -0.098 pp 1.71% -0.793 pp USD4.52 +65.9% 5 qtrs
33 UBS GROUP AG 231.3K +136.4K (+143.7%) 1.73M +910.0K (+110.3%) 0.41% +0.242 pp 0.00% +0.000 pp USD8.86 -15.3% 13 qtrs
34 JANE STREET GROUP, LLC 224.9K +108.0K (+92.4%) 1.69M +670.8K (+66.0%) 0.40% +0.192 pp 0.00% +0.000 pp USD10.09 -25.7% 13 qtrs
35 PRIVIUM FUND MANAGEMENT B.V. 210.0K +12.5K (+6.4%) 1.58M -140.9K (-8.2%) 0.37% +0.021 pp 0.29% -0.019 pp USD8.18 -8.3% 10 qtrs
36 WOODLINE PARTNERS LP 200.0K +200.0K (+100.0%) 1.50M +1.5M (+100.0%) 0.36% +0.356 pp 0.01% +0.006 pp USD7.50 +0.0% 1 qtrs NEW
37 BARCLAYS PLC 170.6K +55.8K (+48.6%) 1.28M +38.3K (+3.1%) 0.30% +0.099 pp 0.00% +0.000 pp USD10.99 -31.8% 16 qtrs
38 SCHONFELD STRATEGIC ADVISORS LLC 162.0K -17.1K (-9.5%) 1.21M -341.3K (-21.9%) 0.29% -0.032 pp 0.01% -0.004 pp USD8.69 -13.7% 2 qtrs
39 NUVEEN, LLC 158.8K +64.9K (+69.0%) 1.19M +374.6K (+45.9%) 0.28% +0.115 pp 0.00% +0.000 pp USD4.97 +50.9% 4 qtrs
40 DEKABANK DEUTSCHE GIROZENTRALE 30.0K +— (+0.0%) 1.17M +12.0K (+1.0%) 0.05% 0.000 pp 0.00% +0.000 pp USD20.26 -63.0% 9 qtrs
41 INVESCO LTD. 153.1K +26.6K (+21.0%) 1.15M +48.6K (+4.4%) 0.27% +0.047 pp 0.00% +0.000 pp USD7.39 +1.5% 17 qtrs
42 PERIGON WEALTH MANAGEMENT, LLC 146.1K +— (+0.0%) 1.10M -173.9K (-13.7%) 0.26% -0.001 pp 0.02% -0.006 pp USD21.94 -65.8% 17 qtrs
43 BANK OF NEW YORK MELLON CORP 136.7K -5.0K (-3.5%) 1.03M -206.0K (-16.7%) 0.24% -0.010 pp 0.00% 0.000 pp USD22.31 -66.4% 20 qtrs
44 WELLINGTON MANAGEMENT GROUP LLP 130.3K -5.2K (-3.9%) 976.9K -200.3K (-17.0%) 0.23% -0.010 pp 0.00% +0.000 pp USD8.69 -13.7% 17 qtrs
45 ADAR1 CAPITAL MANAGEMENT, LLC 116.7K +100.0K (+598.4%) 875.3K +730.1K (+502.7%) 0.21% +0.178 pp 0.06% +0.051 pp USD7.67 -2.2% 2 qtrs
46 D. E. SHAW & CO., INC. 111.8K +101.7K (+1,007.1%) 838.7K +750.9K (+855.5%) 0.20% +0.181 pp 0.00% +0.000 pp USD9.53 -21.3% 8 qtrs
47 SILVERARC CAPITAL MANAGEMENT, LLC 100.0K +100.0K (+100.0%) 750.0K +750.0K (+100.0%) 0.18% +0.178 pp 0.10% +0.104 pp USD7.50 +0.0% 1 qtrs NEW
48 MILLENNIUM MANAGEMENT LLC 96.4K -1.1M (-91.6%) 722.7K -9.3M (-92.8%) 0.17% -1.884 pp 0.00% -0.004 pp USD5.81 +29.1% 21 qtrs
49 AMERICAN CENTURY COMPANIES INC 91.1K +21.5K (+30.8%) 683.1K +78.1K (+12.9%) 0.16% +0.038 pp 0.00% +0.000 pp USD9.96 -24.7% 7 qtrs
50 RAFFERTY ASSET MANAGEMENT, LLC 83.4K +83.4K (+100.0%) 625.6K +625.6K (+100.0%) 0.15% +0.149 pp 0.00% +0.002 pp USD7.50 +0.0% 1 qtrs NEW
51 ENGINEERS GATE MANAGER LP 74.3K +74.3K (+100.0%) 557.0K +557.0K (+100.0%) 0.13% +0.132 pp 0.01% +0.007 pp USD7.50 +0.0% 8 qtrs
52 SQUAREPOINT OPS LLC 71.7K +24.9K (+53.1%) 537.9K +130.9K (+32.2%) 0.13% +0.044 pp 0.00% +0.000 pp USD5.02 +49.4% 3 qtrs
53 FMR LLC 65.6K +79.0 (+0.1%) 492.4K -77.4K (-13.6%) 0.12% 0.000 pp 0.00% +0.000 pp USD4.74 +58.2% 21 qtrs
54 XTX TOPCO LTD 65.0K +25.0K (+62.6%) 487.7K +140.2K (+40.4%) 0.12% +0.044 pp 0.01% -0.005 pp USD5.17 +45.1% 5 qtrs
55 ALLIANCEBERNSTEIN L.P. 55.1K -10.2K (-15.6%) 413.3K -154.1K (-27.2%) 0.10% -0.019 pp 0.00% +0.000 pp USD18.50 -59.5% 13 qtrs
56 RHUMBLINE ADVISERS 53.8K -10.3K (-16.1%) 403.8K -153.9K (-27.6%) 0.10% -0.019 pp 0.00% 0.000 pp USD20.61 -63.6% 20 qtrs
57 PRINCIPIA WEALTH ADVISORY, LLC 53.7K +53.7K (+100.0%) 402.5K +402.5K (+100.0%) 0.10% +0.096 pp 0.25% +0.252 pp USD7.50 +0.0% 1 qtrs NEW
58 WALLEYE CAPITAL LLC 50.8K +50.8K (+100.0%) 380.7K +380.7K (+100.0%) 0.09% +0.090 pp 0.00% +0.001 pp USD7.50 +0.0% 1 qtrs NEW
59 BRIDGEWAY CAPITAL MANAGEMENT, LLC 50.0K +— (+0.0%) 375.0K -59.5K (-13.7%) 0.09% 0.000 pp 0.01% -0.001 pp USD6.08 +23.4% 4 qtrs
60 PANAGORA ASSET MANAGEMENT INC 47.0K +— (+0.0%) 352.3K -55.9K (-13.7%) 0.08% 0.000 pp 0.00% 0.000 pp USD8.69 -13.7% 2 qtrs
61 WELLS FARGO & COMPANY/MN 46.6K +15.6K (+50.4%) 349.7K +80.4K (+29.8%) 0.08% +0.028 pp 0.00% +0.000 pp USD11.54 -35.0% 20 qtrs
62 QUANTINNO CAPITAL MANAGEMENT LP 46.3K +10.9K (+30.6%) 347.3K +39.2K (+12.7%) 0.08% +0.019 pp 0.00% 0.000 pp USD8.41 -10.8% 2 qtrs
63 DECHENG CAPITAL LLC 44.3K -48.4K (-52.2%) 332.3K -473.6K (-58.8%) 0.08% -0.087 pp 0.04% -0.096 pp USD27.48 -72.7% 8 qtrs
64 CREATIVE PLANNING 44.2K +6.5K (+17.2%) 331.5K +3.8K (+1.1%) 0.08% +0.011 pp 0.00% +0.000 pp USD8.52 -12.0% 2 qtrs
65 JAIN GLOBAL LLC 40.5K +40.5K (+100.0%) 303.5K +303.5K (+100.0%) 0.07% +0.072 pp 0.00% +0.002 pp USD7.50 +0.0% 1 qtrs NEW
66 EXODUSPOINT CAPITAL MANAGEMENT, LP 39.2K +39.2K (+100.0%) 293.8K +293.8K (+100.0%) 0.07% +0.070 pp 0.00% +0.002 pp USD7.50 +0.0% 1 qtrs NEW
67 PRICE T ROWE ASSOCIATES INC /MD/ 38.7K -6.3K (-13.9%) 291.0K -101.0K (-25.8%) 0.07% -0.012 pp 0.00% +0.000 pp USD13.03 -42.4% 17 qtrs
68 RANGELEY CAPITAL, LLC 38.7K -4.0K (-9.4%) 290.0K -80.8K (-21.8%) 0.07% -0.007 pp 0.24% -0.080 pp USD7.17 +4.6% 3 qtrs
69 AQR CAPITAL MANAGEMENT LLC 36.1K +180.0 (+0.5%) 270.6K -41.4K (-13.3%) 0.06% +0.000 pp 0.00% 0.000 pp USD4.90 +53.1% 4 qtrs
70 JUMP FINANCIAL, LLC 33.8K +33.8K (+100.0%) 253.7K +253.7K (+100.0%) 0.06% +0.060 pp 0.00% +0.003 pp USD7.50 +0.0% 1 qtrs NEW
71 TUDOR INVESTMENT CORP ET AL 31.8K +6.0K (+23.5%) 238.6K +14.7K (+6.6%) 0.06% +0.011 pp 0.00% +0.000 pp USD14.41 -48.0% 7 qtrs
72 PROFUND ADVISORS LLC 30.9K +30.9K (+100.0%) 231.4K +231.4K (+100.0%) 0.06% +0.055 pp 0.01% +0.007 pp USD7.50 +0.0% 1 qtrs NEW
73 AXQ CAPITAL, LP 30.8K +17.9K (+138.8%) 230.7K +118.7K (+106.1%) 0.05% +0.032 pp 0.05% +0.009 pp USD8.00 -6.3% 2 qtrs
74 ACADIAN ASSET MANAGEMENT LLC 30.1K -25.0K (-45.3%) 225.0K -253.0K (-52.9%) 0.05% -0.045 pp 0.00% -0.001 pp USD3.42 +119.3% 5 qtrs
75 HARBOR CAPITAL ADVISORS, INC. 29.7K +17.8K (+149.7%) 223.0K +120.0K (+116.5%) 0.05% +0.032 pp 0.02% +0.009 pp USD5.79 +29.5% 4 qtrs
76 THRIVENT FINANCIAL FOR LUTHERANS 28.9K +28.9K (+100.0%) 217.0K +217.0K (+100.0%) 0.05% +0.052 pp 0.00% +0.000 pp USD7.50 +0.0% 1 qtrs NEW
77 KERA CAPITAL PARTNERS, INC. 24.1K +— (+0.0%) 213.2K +4.1K (+2.0%) 0.04% 0.000 pp 0.03% -0.005 pp USD3.71 +102.2% 3 qtrs
78 MARSHALL WACE, LLP 27.8K -118.1K (-81.0%) 208.2K -1.1M (-83.6%) 0.05% -0.211 pp 0.00% -0.001 pp USD8.90 -15.7% 8 qtrs
79 MAN GROUP PLC 27.0K +8.5K (+46.2%) 202.8K +42.1K (+26.2%) 0.05% +0.015 pp 0.00% +0.000 pp USD4.78 +56.9% 4 qtrs
80 STRS OHIO 25.1K +— (+0.0%) 188.3K -29.9K (-13.7%) 0.04% 0.000 pp 0.00% 0.000 pp USD8.69 -13.7% 2 qtrs
81 METLIFE INVESTMENT MANAGEMENT, LLC 25.1K +6.7K (+36.4%) 188.2K +28.3K (+17.7%) 0.04% +0.012 pp 0.00% +0.000 pp USD13.64 -45.0% 20 qtrs
82 PELOTON WEALTH STRATEGISTS 25.0K +— (+0.0%) 188.0K -29.0K (-13.4%) 0.04% 0.000 pp 0.07% -0.013 pp USD12.73 -41.1% 15 qtrs
83 TRUIST FINANCIAL CORP 25.0K +25.0K (+100.0%) 187.5K +187.5K (+100.0%) 0.04% +0.045 pp 0.00% +0.000 pp USD7.50 +0.0% 1 qtrs NEW
84 VIRTUS INVESTMENT ADVISERS, INC. 24.5K +24.5K (+100.0%) 184.1K +184.1K (+100.0%) 0.04% +0.044 pp 0.05% +0.050 pp USD7.50 +0.0% 1 qtrs NEW
85 MIRAE ASSET GLOBAL ETFS HOLDINGS LTD. 23.5K +4.6K (+24.5%) 176.9K +12.7K (+7.7%) 0.04% +0.008 pp 0.00% +0.000 pp USD16.92 -55.7% 7 qtrs
86 MITSUBISHI UFJ KOKUSAI ASSET MANAGEMENT CO., LTD. 23.8K +23.8K (+100.0%) 174.5K +174.5K (+100.0%) 0.04% +0.043 pp 0.00% +0.000 pp USD7.50 +0.0% 1 qtrs NEW
87 ENTRYPOINT CAPITAL, LLC 22.3K +22.3K (+100.0%) 167.4K +167.4K (+100.0%) 0.04% +0.040 pp 0.07% +0.065 pp USD7.50 +0.0% 1 qtrs NEW
88 PDT PARTNERS, LLC 20.1K +— (+0.0%) 150.7K -23.9K (-13.7%) 0.04% 0.000 pp 0.01% -0.001 pp USD5.57 +34.6% 8 qtrs
89 COMMONWEALTH EQUITY SERVICES, LLC 20.0K +20.0K (+100.0%) 150.1K +150.1K (+100.0%) 0.04% +0.036 pp 0.00% +0.000 pp USD7.50 +0.0% 1 qtrs NEW
90 CITADEL ADVISORS LLC 19.9K +19.9K (+100.0%) 149.2K +149.2K (+100.0%) 0.04% +0.035 pp 0.00% +0.000 pp USD7.50 +0.0% 21 qtrs
91 LANDING POINT FINANCIAL GROUP, LLC 19.0K +19.0K (+100.0%) 142.5K +142.5K (+100.0%) 0.03% +0.034 pp 0.07% +0.071 pp USD7.50 +0.0% 1 qtrs NEW
92 ROCKEFELLER CAPITAL MANAGEMENT L.P. 18.1K +17.9K (+14,343.2%) 135.4K +134.3K (+12,368.2%) 0.03% +0.032 pp 0.00% +0.000 pp USD7.51 -0.1% 2 qtrs
93 POLYMER CAPITAL MANAGEMENT (US) LLC 18.0K +18.0K (+100.0%) 135.3K +135.3K (+100.0%) 0.03% +0.032 pp 0.01% +0.014 pp USD7.50 +0.0% 1 qtrs NEW
94 PARALLEL ADVISORS, LLC 17.9K -1.9K (-9.4%) 134.2K -37.4K (-21.8%) 0.03% -0.003 pp 0.00% -0.001 pp USD21.34 -64.9% 9 qtrs
95 INTECH INVESTMENT MANAGEMENT LLC 17.6K -1.0K (-5.5%) 132.2K -29.9K (-18.4%) 0.03% -0.002 pp 0.00% 0.000 pp USD7.44 +0.8% 6 qtrs
96 SUSQUEHANNA INTERNATIONAL GROUP, LLP 16.9K +16.9K (+100.0%) 126.8K +126.8K (+100.0%) 0.03% +0.030 pp 0.00% +0.000 pp USD7.50 +0.0% 1 qtrs NEW
97 BALLENTINE PARTNERS, LLC 16.5K +170.0 (+1.0%) 124.0K -18.2K (-12.8%) 0.03% +0.000 pp 0.00% 0.000 pp USD8.68 -13.6% 2 qtrs
Ownership breakdown by holder

ETF Ownership

Top ETFs holding this stock Held by 87 ETFs in our universe
# ETF Weight Est. AUM exposure TER
1 Virtus Biotech Clinical Trials ETF BBC 0.86% 493.9K 0.65%
2 ALPS Medical Breakthroughs ETF SBIO 0.33% 702.8K 0.50%
3 Xtrackers Bloomberg Commodity ex-Agriculture & Livestock Swap UCITS ETF 2C XBCU.L 0.29% 2.23M 0.29%
4 Xtrackers Bloomberg Commodity ex-Agriculture & Livestock Swap UCITS ETF 3C GBP Hedged XDBG.L 0.29% 2.23M 0.39%
5 State Street SPDR S&P Biotech ETF XBI 0.18% 19.86M 0.35%
6 Global X - S&P Biotech ETF CURE.AX 0.18% 65.6K 0.45%
7 iShares Micro-Cap ETF IWC 0.13% 1.90M 0.60%
8 State Street SPDR S&P Kensho New Economies Composite ETF KOMP 0.12% 3.38M 0.20%
9 Vanguard U.S. Momentum Factor ETF VFMO 0.08% 1.39M 0.13%
10 Innovator U.S. Small Cap Managed Floor ETF RFLR 0.06% 56.3K 0.89%

Insider Activity

Insider Activity — Latest Quarter
Ratio by transactions
1.50
Neutral
Ratio by volume
3.00
Bullish
Buys
6
Sells
4
Shares acquired
1.23M
Shares disposed
1.5K
Cash buys
Cash sales
2.00
Net activity
+1,230,610
Insider buys vs sells (history) From To
Recent insider transactions From To
Date Person Role Transaction A/D Security Shares Price Value Owned after D/I Filing
2026-03-25 Simms Christopher Paul Officer A-Award A Stock Option (Right to Buy) 219,000 9.88 2.16M 219,000 D
2026-03-25 Kirn David Director / Officer A-Award A Stock Option (Right to Buy) 750,000 9.88 7.41M 750,000 D
2026-03-25 Bizily Scott Officer A-Award A Stock Option (Right to Buy) 217,000 9.88 2.14M 217,000 D
2026-03-20 Gupta Ashoo Officer M-Exempt A Common Stock 865 0.00 47,224 D
2026-01-05 SBLENDORIO GLENN Director A-Award A Stock Option (Right to Buy) 45,000 7.30 328.5K 45,000 D
2025-12-20 Gupta Ashoo Officer S-Sale D Common Stock 310 8.68 2.7K 46,218 D
2025-12-16 Bizily Scott Officer M-Exempt D Stock Option (Right to Buy) 1,635 4.14 6.8K 73,595 D
2025-12-12 THEUER CHARLES Director M-Exempt D Stock Option (Right to Buy) 9,333 1.14 10.6K 0 D
2025-12-09 Simms Christopher Paul Officer Stock Option (Right to Buy) 300,000 9.38 2.81M 0 D
2025-12-09 Humer Kristian 0 0.00 0
2025-11-17 Bizily Scott Officer M-Exempt D Stock Option (Right to Buy) 1,635 4.14 6.8K 75,230 D
2025-10-24 Bizily Scott Officer M-Exempt D Stock Option (Right to Buy) 1,084 6.49 7.0K 9,295 D
2025-10-16 Bizily Scott Officer M-Exempt D Stock Option (Right to Buy) 1,635 4.14 6.8K 76,865 D
2025-10-09 Bizily Scott Officer S-Sale D Common Stock 2,408 10.00 24.1K 5,188 D
2025-09-30 Gupta Ashoo Officer Stock Option (Right to Buy) 27,700 22.69 628.5K 0 D
2025-09-23 Bizily Scott Officer S-Sale D Common Stock 2,407 8.00 19.3K 7,596 D
2025-06-17 Tomasello Shawn Director A-Award A Stock Option (Right to Buy) 22,500 4.15 93.4K 22,500 D
2025-06-17 THEUER CHARLES Director A-Award A Stock Option (Right to Buy) 22,500 4.15 93.4K 22,500 D
2025-06-17 Miller-Rich Nancy Director A-Award A Stock Option (Right to Buy) 22,500 4.15 93.4K 22,500 D
2025-06-17 MILLIGAN JOHN F Director A-Award A Stock Option (Right to Buy) 33,750 4.15 140.1K 33,750 D
2025-06-17 GRAY SUSANNAH Director A-Award A Stock Option (Right to Buy) 22,500 4.15 93.4K 22,500 D
2025-06-17 Chacko Jacob Director A-Award A Stock Option (Right to Buy) 22,500 4.15 93.4K 22,500 D
2025-03-06 Mehra Uneek Officer A-Award A Stock Option (Right to Buy) 130,000 4.14 538.2K 130,000 D
2025-03-06 Kirn David Director / Officer A-Award A Stock Option (Right to Buy) 267,500 4.14 1.11M 267,500 D
2025-03-06 Kim Robert Young Officer A-Award A Stock Option (Right to Buy) 92,300 4.14 382.1K 92,300 D
2025-03-06 Kamal Fariborz Officer A-Award A Stock Option (Right to Buy) 178,400 4.14 738.6K 178,400 D
2025-03-06 Bizily Scott Officer A-Award A Stock Option (Right to Buy) 78,500 4.14 325.0K 78,500 D
2024-12-09 RA CAPITAL MANAGEMENT, L.P. 10% Owner J-Other D Common Stock 535,000 0.00 4,563,211 I
2024-11-13 RA CAPITAL MANAGEMENT, L.P. 10% Owner Warrant (Right to Buy) 3,075,000 0.00 307.50 0 I
2024-11-08 BVF PARTNERS L P/IL Other J-Other D Common Stock, $0.0001 par value 240,000 0.00 87,911 D
2024-09-16 Bizily Scott Officer M-Exempt D Stock Option (Right To Buy) 500 6.49 3.2K 10,379
2024-08-19 Bizily Scott Officer M-Exempt D Stock Option (Right To Buy) 500 6.49 3.2K 10,879
2024-07-22 BVF PARTNERS L P/IL 10% Owner D Common Stock, $0.0001 par value 0 0.00 3,892,237
2024-07-16 Bizily Scott Officer M-Exempt A Common Stock 1,250 8.04 10.1K 8,531
2024-07-11 Bizily Scott Officer M-Exempt A Common Stock 1,996 15.78 31.5K 8,777
2024-07-10 Kirn David Director / Officer M-Exempt A Common Stock 1,270 15.78 20.0K 1,072,076
2024-07-01 Bizily Scott Officer M-Exempt A Common Stock 2,916 8.04 23.4K 5,985
2024-06-24 Kirn David Director / Officer M-Exempt A Common Stock 12,930 14.42 186.5K 1,072,083
2024-06-17 Bizily Scott Officer M-Exempt D Stock Option (Right To Buy) 1,250 8.04 10.1K 36,668
2024-05-21 Tomasello Shawn Director A-Award A Stock Option (Right To Buy) 22,500 25.15 565.9K 22,500
2024-05-21 THEUER CHARLES Director A-Award A Stock Option (Right To Buy) 22,500 25.15 565.9K 22,500
2024-05-21 Miller-Rich Nancy Director A-Award A Stock Option (Right To Buy) 22,500 25.15 565.9K 22,500
2024-05-21 MILLIGAN JOHN F Director A-Award A Stock Option (Right To Buy) 26,791 25.15 673.8K 26,791
2024-05-21 GRAY SUSANNAH Director A-Award A Stock Option (Right To Buy) 22,500 25.15 565.9K 22,500
2024-05-21 Chacko Jacob Director A-Award A Stock Option (Right To Buy) 22,500 25.15 565.9K 22,500
2024-05-16 Bizily Scott Officer M-Exempt A Common Stock 1,250 8.04 10.1K 3,487
2024-04-16 Bizily Scott Officer M-Exempt D Stock Option (Right To Buy) 1,250 8.04 10.1K 39,168
2024-04-01 Bizily Scott Officer M-Exempt A Common Stock 1,996 15.78 31.5K 7,981
2024-03-27 Bizily Scott Officer S-Sale D Common Stock 5,833 35.04 204.4K 1,737
2024-03-18 Bizily Scott Officer M-Exempt A Common Stock 1,250 8.04 10.1K 3,487
2024-02-27 Bizily Scott Officer M-Exempt D Stock Option (Right To Buy) 1,909 20.24 38.6K 48,091
2024-02-16 Bizily Scott Officer S-Sale D Common Stock 1,750 27.67 48.4K 1,737
2024-02-08 Kirn David Director / Officer S-Sale D Common Stock 92,001 27.13 2.50M 1,059,153
2024-02-08 Bizily Scott Officer M-Exempt D Stock Option (Right to Buy) 2,916 8.04 23.4K 45,834
2024-02-07 Kim Robert Young Officer D Common Stock 0 0.00 1,595
2024-02-05 Kim Robert Young Officer M-Exempt D Stock Option (Right to Buy) 12,000 18.66 223.9K 138,000
2024-01-23 Kirn David Director / Officer S-Sale D Common Stock 5,696 18.41 104.9K 1,151,154
2024-01-05 Kirn David Director / Officer S-Sale D Common Stock 28,104 19.56 549.8K 1,156,983
2024-01-04 VIKING GLOBAL INVESTORS LP 10% Owner S-Sale D Common Stock 540,000 19.53 10.55M 4,247,914
2024-01-04 Kirn David Director / Officer S-Sale D Common Stock 40,732 20.31 827.2K 1,185,087
2023-12-18 Kirn David Director / Officer S-Sale D Common Stock 4,702 18.13 85.2K 1,225,819
2023-12-15 Kirn David Director / Officer S-Sale D Common Stock 28,632 17.27 494.4K 1,230,521
2023-12-11 Mehra Uneek Officer A-Award A Stock Option (Right to Buy) 75,000 14.42 1.08M 75,000
2023-12-11 Kirn David Director / Officer A-Award A Stock Option (Right to Buy) 590,000 14.42 8.51M 590,000
2023-12-11 Kim Robert Young Officer A-Award A Stock Option (Right to Buy) 250,000 14.42 3.61M 250,000
2023-12-11 Kamal Fariborz Officer A-Award A Stock Option (Right to Buy) 260,000 14.42 3.75M 260,000
2023-12-11 Bizily Scott Officer A-Award A Stock Option (Right to Buy) 130,000 14.42 1.87M 130,000
2023-10-01 Mehra Uneek Officer A-Award A Stock Option (Right to Buy) 229,634 12.73 2.92M 229,634
2023-09-22 Mehra Uneek Officer 0 0.00 0
2023-06-08 Bizily Scott Officer M-Exempt D Stock Option (Right to Buy) 3,750 8.04 30.2K 48,750
2023-06-01 Bizily Scott Officer M-Exempt D Stock Option (Right to Buy) 1,875 6.49 12.2K 18,375
2023-05-23 Tomasello Shawn Director A-Award A Stock Option (Right to Buy) 22,500 17.98 404.6K 22,500
2023-05-23 THEUER CHARLES Director A-Award A Stock Option (Right to Buy) 22,500 17.98 404.6K 22,500
2023-05-23 Miller-Rich Nancy Director A-Award A Stock Option (Right to Buy) 22,500 17.98 404.6K 22,500
2023-05-23 MILLIGAN JOHN F Director A-Award A Stock Option (Right to Buy) 33,750 17.98 606.8K 33,750
2023-05-23 Kasahara Noriyuki Director A-Award A Stock Option (Right to Buy) 22,500 17.98 404.6K 22,500
2023-05-23 GRAY SUSANNAH Director A-Award A Stock Option (Right to Buy) 22,500 17.98 404.6K 22,500
2023-05-23 Chacko Jacob Director A-Award A Stock Option (Right to Buy) 22,500 17.98 404.6K 22,500
2023-05-15 Moretti August J Officer M-Exempt D Stock Option (Right to Buy) 3,000 9.41 28.2K 217,060
2023-05-09 VIKING GLOBAL INVESTORS LP 10% Owner P-Purchase A Common Stock 850,000 16.00 13.60M 4,787,914
2023-05-02 Kirn David Director / Officer G-Gift D Common Stock 600,000 0.00 1,259,153
2023-04-21 Chacko Jacob Director M-Exempt D Stock Option (Right to Buy) 5,000 9.41 47.1K 32,500
2023-04-21 Bizily Scott Officer M-Exempt D Stock Option (Right to Buy) 3,750 8.04 30.2K 52,500
2023-03-24 Kim Robert Young Officer D Stock Options (Right to Buy) 70,000 15.78 1.10M 0
2023-03-01 Bizily Scott Officer S-Sale D Common Stock 2,248 19.30 43.4K 2,109
2023-02-22 Kirn David Director / Officer S-Sale D Common Stock 16,449 20.22 332.7K 1,859,153
2023-02-21 Kirn David Director / Officer S-Sale D Common Stock 17,090 20.93 357.7K 1,876,509
2023-02-10 Moretti August J Officer A-Award A Stock Option (Right to Buy) 50,000 20.24 1.01M 50,000
2023-02-10 Kirn David Director / Officer A-Award A Stock Option (Right to Buy) 222,000 20.24 4.49M 222,000
2023-02-10 Kamal Fariborz Officer A-Award A Stock Option (Right to Buy) 75,000 20.24 1.52M 75,000
2023-02-10 Bizily Scott Officer A-Award A Stock Option (Right to Buy) 50,000 20.24 1.01M 50,000
2023-01-20 Kirn David Officer S-Sale D Common Stock 8,625 20.19 174.1K 1,893,599
2023-01-19 Kirn David Officer S-Sale D Common Stock 10,899 20.03 218.3K 1,902,224
2022-12-21 Moretti August J Officer M-Exempt A Common Stock 3,000 9.41 28.2K 6,595
2022-12-16 Kirn David Officer S-Sale D Common Stock 27,595 22.66 625.4K 1,939,472
2022-12-15 Kirn David Officer S-Sale D Common Stock 31,433 23.56 740.6K 1,968,567
2022-12-01 Bizily Scott Officer S-Sale D Common Stock 400 21.52 8.6K 4,332
2022-09-23 Kasahara Noriyuki Director A-Award A Stock Option (Right to Buy) 45,000 8.06 362.7K 45,000
2022-09-23 Kamal Fariborz Officer A-Award A Stock Option (Right to Buy) 15,000 8.06 120.9K 15,000
2022-09-01 Moretti August J Officer A-Award D Stock Option (Right to Buy) 60,000 0.00 60,000
2022-09-01 Kamal Fariborz Officer A-Award A Stock Option (Right to Buy) 60,000 0.00 60,000
2022-09-01 FISHMAN ROBERT S Officer A-Award A Stock Option (Right to Buy) 60,000 0.00 60,000
2022-09-01 Bizily Scott Officer A-Award A Stock Option (Right to Buy) 60,000 0.00 60,000
2022-06-18 Bizily Scott Officer A-Award A Stock Option (Right to Buy) 24,000 0.00 24,000
2022-06-16 BVF PARTNERS L P/IL 10% Owner D Common Stock 0 0.00 2,132,411
2022-05-23 Tomasello Shawn Director A-Award A Stock Option (Right to Buy) 22,500 0.00 22,500
2022-05-23 THEUER CHARLES Director A-Award A Stock Option (Right to Buy) 22,500 0.00 22,500
2022-05-23 Miller-Rich Nancy Director A-Award A Stock Option (Right to Buy) 22,500 7.77 174.8K 22,500
2022-05-23 MILLIGAN JOHN F Director A-Award A Stock Option (Right to Buy) 33,750 0.00 33,750
2022-05-23 GRAY SUSANNAH Director A-Award A Stock Option (Right to Buy) 22,500 0.00 22,500
2022-05-23 Chacko Jacob Director A-Award A Stock Option (Right to Buy) 22,500 0.00 22,500
2022-02-01 Zimmermann Carolyne Officer A-Award A Stock Option (Right to Buy) 35,000 15.78 552.3K 35,000
2022-02-01 Moretti August J Officer A-Award D Stock Option (Right to Buy) 65,000 15.78 1.03M 65,000
2022-02-01 Kirn David Director / Officer / 10% Owner A-Award A Stock Option (Right to Buy) 150,000 15.78 2.37M 150,000
2022-02-01 Kamal Fariborz Officer A-Award A Stock Option (Right to Buy) 70,000 15.78 1.10M 70,000
2022-02-01 FISHMAN ROBERT S Officer A-Award A Stock Option (Right to Buy) 65,000 15.78 1.03M 65,000
2021-10-22 SCHAFFER DAVID Director S-Sale D Common Stock 1,900 31.00 58.9K 901,215
2021-10-21 SCHAFFER DAVID Director S-Sale D Common Stock 22,820 31.56 720.2K 903,115
2021-10-20 SCHAFFER DAVID Director S-Sale D Common Stock 11,565 31.02 358.8K 925,935
2021-09-30 SCHAFFER DAVID Director S-Sale D Common Stock 7,836 26.69 209.2K 942,049
2021-09-29 SCHAFFER DAVID Director S-Sale D Common Stock 7,806 27.99 218.5K 958,950
2021-09-28 SCHAFFER DAVID Director S-Sale D Common Stock 13,812 30.52 421.5K 966,856
2021-09-27 SCHAFFER DAVID Director S-Sale D Common Stock 6,157 33.51 206.3K 980,768
2021-06-07 Zimmermann Carolyne Officer A-Award A Stock Option (Right to Buy) 60,000 26.83 1.61M 60,000
2021-05-17 Tomasello Shawn Director A-Award A Stock Option (Right to Buy) 22,500 26.89 605.0K 22,500
2021-05-17 THEUER CHARLES Director A-Award A Stock Option (Right to Buy) 22,500 26.89 605.0K 22,500
2021-05-17 SCHAFFER DAVID Director A-Award A Stock Option (Right to Buy) 22,500 26.89 605.0K 22,500
2021-05-17 Miller-Rich Nancy Director A-Award A Stock Option (Right to Buy) 22,500 26.89 605.0K 22,500
2021-05-17 MILLIGAN JOHN F Director A-Award A Stock Option (Right to Buy) 22,500 26.89 605.0K 22,500
2021-05-17 GRAY SUSANNAH Director A-Award A Stock Option (Right to Buy) 22,500 26.89 605.0K 22,500
2021-05-17 Chacko Jacob Director A-Award A Stock Option (Right to Buy) 22,500 26.89 605.0K 22,500
2021-04-12 Moretti August J Officer M-Exempt D Stock Option (Right to Buy) 1,000 9.41 9.4K 223,060
2021-03-08 Moretti August J Officer A-Award A Stock Option (Right to Buy) 70,000 41.66 2.92M 70,000
2021-03-08 Kirn David Director / Officer / 10% Owner A-Award A Stock Option (Right to Buy) 150,000 41.66 6.25M 150,000
2021-03-08 Kamal Fariborz Officer A-Award A Stock Option (Right to Buy) 60,000 41.66 2.50M 60,000
2020-12-15 YAO TONY DUNG LING Director C-Conversion A Common Stock 2,864 0.00 2,864
2020-12-15 VIKING GLOBAL INVESTORS LP 10% Owner P-Purchase A Common Stock 1,100,000 23.00 25.30M 3,937,914
2020-12-15 MILLIGAN JOHN F Director P-Purchase A Common Stock 100,000 23.00 2.30M 100,000
2020-12-15 Kamal Fariborz Officer P-Purchase A Common Stock 4,347 23.00 100.0K 4,347
2020-12-10 YAO TONY DUNG LING Director D Series B Preferred Stock 2,864 17.46 50.0K 0
2020-12-10 VIKING GLOBAL INVESTORS LP 10% Owner I Series C Redeemable Convertible Preferred Stock 833,333 0.00 0
2020-12-10 Tomasello Shawn Director D Stock Option (Right to Buy) 45,000 18.66 839.7K 0
2020-12-10 THEUER CHARLES Director D Stock Option (Right to Buy) 13,684 3.19 43.7K 0
2020-12-10 SCHAFFER DAVID Director / 10% Owner I Common Stock 0 0.00 2,000,000
2020-12-10 Moretti August J Officer D Common Stock 0 0.00 1,000
2020-12-10 Miller-Rich Nancy Director D Stock Option (Right to Buy) 45,000 18.66 839.7K 0
2020-12-10 MILLIGAN JOHN F Director D Stock Option (Right to Buy) 335,243 15.97 5.35M 0
2020-12-10 Kirn David Director / Officer / 10% Owner D Common Stock 0 0.00 2,000,000
2020-12-10 Kamal Fariborz Officer D Stock Option (Right to Buy) 71,930 8.27 594.9K 0
2020-12-10 GRAY SUSANNAH Director D Stock Option (Right to Buy) 45,000 15.97 718.7K 0
2020-12-10 FISHMAN ROBERT S Officer D Stock Option (Right to Buy) 240,000 18.66 4.48M 0
2020-12-10 Chacko Jacob Director D Stock Option (Right to Buy) 22,500 15.10 339.8K 0
2020-12-10 Burkoth William T. Director 0 0.00 0

Executive team

Top executives
EBIT / Employee
-702.9K
Shares Outstanding
52.27M

Executive compensation

Executive compensation (annual)
# Year Executive Salary Bonus Stock award Option award Incentive Other Total % Stock-
based
Filing
1 2025 Kristian Humer Chief Financial Officer 66.0K 50.0K 3.87M 247.00 3.99M 97.09%
2 2025 David Kirn, M.D. President and Chief Executive Officer 667.3K 822.8K 560.6K 744.00 2.05M 40.11%
3 2025 Fariborz Kamal, Ph.D. Former Chief Operating Officer & President 551.7K 548.7K 339.5K 1.6K 1.44M 38.06%
4 2024 David Kirn, M.D. President and Chief Executive Officer 662.8K 292.7K 53.6K 1.01M 0.00%
5 2024 David Kirn, M.D. Chief Executive Officer 662.8K 292.7K 53.6K 1.01M 0.00%
6 2024 Uneek Mehra Chief Financial and Business Officer 545.8K 100.0K 178.1K 823.9K 0.00%
7 2024 Fariborz Kamal, Ph.D. Former Chief Operating Officer & President 546.3K 180.6K 7.7K 734.6K 0.00%
8 2024 Fariborz Kamal, Ph.D. Chief Operating Officer & President 546.3K 180.6K 7.7K 734.6K 0.00%
9 2023 David Kirn, M.D. Chief Executive Officer 596.6K 9.28M 395.0K 16.5K 10.29M 90.20%
10 2023 Fariborz Kamal, Ph.D. Chief Operating Officer & President 489.4K 3.76M 296.8K 4.54M 82.70%
11 2023 Robert Kim, M.D. Chief Medical Officer 456.1K 3.26M 232.3K 16.5K 3.96M 82.22%
12 2022 David Kirn, M.D. Chief Executive Officer 585.7K 2.37M 321.8K 13.5K 3.29M 71.99%
13 2022 Fariborz Kamal, Ph.D. Chief Operating Officer & President 469.0K 1.71M 209.4K 2.39M 71.57%
14 2022 August J. Moretti, J.D. Chief Financial Officer 459.6K 1.51M 192.7K 13.5K 2.17M 69.37%
15 2021 David Kirn, M.D. Chief Executive Officer 570.0K 4.39M 228.0K 13.0K 5.20M 84.41%
16 2021 August J. Moretti, J.D. Chief Financial Officer 435.0K 2.05M 139.2K 13.0K 2.64M 77.72%
17 2021 August Moretti Chief Financial Officer 435.0K 2.05M 139.2K 13.0K 2.64M 77.72%
18 2021 Theresa Janke Chief of Staff 385.0K 2.05M 129.4K 9.8K 2.57M 79.63%
19 2020 Robert Fishman, M.D. Chief Medical Officer 89.7K 50.0K 3.16M 44.9K 3.34M 94.47%
20 2020 David Kirn, M.D. Chief Executive Officer 451.2K 237.3K 13.0K 701.5K 0.00%
21 2020 August Moretti Chief Financial Officer 399.7K 220.1K 13.0K 632.8K 0.00%
22 2019 August Moretti Chief Financial Officer 374.2K 1.66M 89.7K 12.5K 2.14M 77.71%
23 2019 David Kirn, M.D. Chief Executive Officer 430.0K 111.8K 12.5K 554.3K 0.00%
CEO compensation breakdown

Proxy statements

Proxy statements (DEF 14A)
Filing date Form type Filing
2026-04-28 DEFA14A
2026-04-28 DEF 14A
2025-04-29 DEFA14A
2025-04-29 DEF 14A

Recent SEC filings

Recent SEC filings
Filing date Form type Filing
2026-05-07 S-3
2026-05-07 8-K
2026-05-07 10-Q
2026-04-28 DEFA14A
2026-04-28 DEF 14A
2026-04-28 ARS
2026-04-07 SC 13G/A
2026-03-30 8-K
2026-03-27 4
2026-03-27 4

Executive team

NameTitleCompensationGender
David H. Kirn Co-Founder, President, CEO & Director 1M
Fariborz Kamal Chief Technical Advisor 892.9K
Theresa Janke Co-Founder & Chief of Staff 652.3K female
Noriyuki Kasahara Chief Scientific Advisor & Member of Scientific Advisory Board 201.3K
John F. Milligan Executive Chairman 150.0K
Kristian Humer CFO and Principal Financial & Accounting Officer 116.2K male
Julian Pei Head of Investor Relations & Corporate Finance
Ashoo Gupta Principal Accounting Officer & Principal Financial Officer male
An Song Chief Translational Medicine Advisor
Katy Barglow Chief Technical Officer
Scott Bizily Chief Legal Officer & Corporate Secretary
ESG Rating
B
BIOTECHNOLOGY
2026
E (Environmental)
54.9 / 56.3
Company / Sector avg.
S (Social)
62.7 / 62.4
Company / Sector avg.
G (Governance)
62.2 / 60.9
Company / Sector avg.
ESG Total
59.9 / 59.9
Company / Sector avg.
ESG Score History BIOTECHNOLOGY
Benchmark vs Sector
Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

Share your view on this stock and instantly see how the community has voted over the last 6 months.

These are community opinions and do not constitute buy or sell advice to act on. The results shown are based on aggregated opinions and are not an investment recommendation, nor do they intend to influence any investment decision.

Dividend history

Earnings history

Earnings reports

Stock splits