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Candel Therapeutics, Inc. (CADL)

USD9.61 -0.26 (-2.63%)
US NASDAQ Healthcare Biotechnology
Address 117 Kendrick Street 2494
Needham, MA, US
CEO Paul-Peter Tak
IPO 2021-07-27
CIK 1841387 ISIN US1374041093

Explore sections of this company profile

Description

Candel Therapeutics, Inc. is a clinical-stage biopharmaceutical firm based in Needham, Massachusetts, dedicated to developing innovative immunotherapies for cancer patients. Its pipeline features CAN-2409, which is presently in Phase II clinical trials for pancreatic and lung cancers, and has progressed to Phase III for prostate cancer. This therapy also successfully completed Phase Ib/II trials for high-grade glioma. Furthermore, the company is advancing CAN-3110, an investigational therapy currently in Phase I clinical trials for recurrent glioblastoma. Established in 2003, the company operated as Advantagene, Inc. until November 2020, when it rebranded as Candel Therapeutics, Inc.

News Sentiment (7d)
Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
USD9.61 -0.26 (-2.63%)
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Volume Profile
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Liquidity & share structure
Average Volume
2M
Beta
-0.48
Float Shares
47.45M
Free Float %
86.4%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
-0.34% +13.07% +74.71% +56.87% +92.03% +57.70% +66.85% +456.88% +27.29% +27.29% +27.29%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
vs.
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Analyst Consensus (10 ratings, all time) Buy
Price Targets & DCF
Current price
9.61
Low 15.00 +56.1%
Consensus 15.00 +56.1%
Median 15.00 +56.1%
High 15.00 +56.1%
DCF (Unlevered) 2.20 -77.1%
DCF (Levered) 2.22 -76.8%

DCF figures are point estimates: small changes in growth or discount-rate assumptions move them materially. Read them as a reference, not a precise target.

Ratings Trend (MoM) 89% Bullish
Rating 2026-05 Change
Strong Buy 0 0
Buy 8 0
Hold 1 0
Sell 0 0
Strong Sell 0 0
Price Target Summary
Period # Analysts Avg Target
Last Month
Last Quarter
Last Year 1
15.00
+56.1%
All Time 1
15.00
+56.1%
Quality scores
Altman Z-Score
2.90
Grey zone
Piotroski F-Score
2 / 9
Weak
MOAT Score
3 / 10
No MOAT
Composite Rating
C
Overall Score
2 / 5
Medium
DCF Score
3 / 5
Medium
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
3 / 5
Medium
P/E Score
1 / 5
Low
P/Book Score
1 / 5
Low
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
  • EPS growth Biotechnology: +29.7%
    +58.6% Q1'26: -160.9% (vs Q1'25)
  • FCF margin FCF growth · Biotechnology: +16.2%
  • EBIT margin Biotechnology: +0.0%
  • ROIC Biotechnology: -16.1%
    Q1'26: +0.0% (vs Q1'25)
  • Share dilution Biotechnology: -3.4%
    +67.2% Q1'26: +96.9% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    -0.04× Q1'26: -0.03× (vs Q1'25)
Valuation Multiples From To
DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (-0.59) × ERP
WACC = 100% × Ke + 0% × Kd (111.3%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Intrinsic value (base): 2.20 Current price: 9.61
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2021
actual
Dec 2022
actual
Dec 2023
actual
Dec 2024
actual
Dec 2025
actual
Dec 2026
7 Rev. Ana.
3 EPS Ana.
Dec 2027
5 Rev. Ana.
3 EPS Ana.
Dec 2028
7 Rev. Ana.
6 EPS Ana.
Dec 2029
3 Rev. Ana.
4 EPS Ana.
Dec 2030
6 Rev. Ana.
2 EPS Ana.
Revenue
125.0K
est: 33.0K (+278.8%)
125.0K
est: 81.3K (+53.8%)
est: 15.5K (-100.0%)
est: 15.5K (-100.0%)
est: 4.35M (-100.0%)
92.50M
92.50M – 92.50M
+2,027.3% YoY
48.37M
48.37M – 48.37M
-47.7% YoY
185.50M
185.50M – 185.50M
+283.5% YoY
442.18M
442.18M – 442.18M
+138.4% YoY
763.83M
763.83M – 763.83M
+72.7% YoY
EBITDA
-25.49M
est: -6.6K (-386,231.3%)
-16.31M
est: -16.2K (-100,263.1%)
-37.43M
est: -3.1K (-1,207,741.2%)
-52.10M
est: 3.1K (-1,681,190.7%)
-47.42M
est: 869.6K (-5,553.0%)
18.50M
18.50M – 18.50M
+2,027.3% YoY
9.67M
9.67M – 9.67M
-47.7% YoY
37.10M
37.10M – 37.10M
+283.5% YoY
88.44M
88.44M – 88.44M
+138.4% YoY
152.77M
152.77M – 152.77M
+72.7% YoY
EBIT
-25.73M
est: -6.6K (-389,746.9%)
-17.09M
est: -16.2K (-105,051.1%)
-38.39M
est: -3.1K (-1,238,719.0%)
-53.09M
est: 3.1K (-1,713,136.5%)
-48.27M
est: 869.6K (-5,650.1%)
18.50M
18.50M – 18.50M
+2,027.3% YoY
9.67M
9.67M – 9.67M
-47.7% YoY
37.10M
37.10M – 37.10M
+283.5% YoY
88.44M
88.44M – 88.44M
+138.4% YoY
152.77M
152.77M – 152.77M
+72.7% YoY
Net Income
-36.12M
est: -63.71M (+43.3%)
-18.79M
est: -22.03M (+14.7%)
-37.94M
est: -34.53M (-9.9%)
-55.18M
est: -72.52M (+23.9%)
-38.18M
est: -22.07M (-73.0%)
-63.66M
-72.86M – -54.46M
-188.5% YoY
-63.44M
-193.11M – 96.55M
+0.3% YoY
24.35M
-90.56M – 140.87M
+138.4% YoY
119.42M
119.42M – 119.42M
+390.4% YoY
261.88M
261.88M – 261.88M
+119.3% YoY
SGA
11.26M
est: 1.67M (+575.5%)
14.06M
est: 4.10M (+242.7%)
14.41M
est: 782.7K (+1,741.2%)
14.06M
est: 637.2K (+2,106.2%)
17.77M
est: 178.74M (-90.1%)
3.80B
3.80B – 3.80B
+2,027.3% YoY
1.99B
1.99B – 1.99B
-47.7% YoY
7.63B
7.63B – 7.63B
+283.5% YoY
18.18B
18.18B – 18.18B
+138.4% YoY
31.40B
31.40B – 31.40B
+72.7% YoY
EPS
-1.26
est: -2.01 (+37.4%)
-0.10
est: -0.70 (+85.7%)
-1.31
est: -1.09 (-20.2%)
-1.74
est: -1.37 (-27.1%)
-0.72
est: -0.42 (-70.8%)
-1.26
-1.38 – -1.03
-197.8% YoY
-0.91
-3.65 – 1.82
+27.4% YoY
0.33
-1.71 – 2.66
+136.5% YoY
2.26
2.26 – 2.26
+578.5% YoY
4.95
4.95 – 4.95
+119.3% YoY
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-11 C 2/5 3/5 1/5 1/5 3/5 1/5 1/5
2026-05-08 C 2/5 3/5 1/5 1/5 3/5 1/5 1/5
2026-05-07 C 2/5 3/5 1/5 1/5 3/5 1/5 1/5
2026-05-06 C 2/5 3/5 1/5 1/5 3/5 1/5 1/5
2026-05-05 C 2/5 3/5 1/5 1/5 3/5 1/5 1/5
2026-05-04 C 2/5 3/5 1/5 1/5 3/5 1/5 1/5
2026-05-01 C 2/5 3/5 1/5 1/5 3/5 1/5 1/5
2026-04-30 C 2/5 3/5 1/5 1/5 3/5 1/5 1/5
2026-04-29 C 2/5 3/5 1/5 1/5 3/5 1/5 1/5
2026-04-28 C 2/5 3/5 1/5 1/5 3/5 1/5 1/5
2026-04-27 C- 1/5 3/5 1/5 1/5 2/5 1/5 1/5
2026-04-24 C- 1/5 3/5 1/5 1/5 2/5 1/5 1/5
2026-04-23 C- 1/5 3/5 1/5 1/5 2/5 1/5 1/5
2026-04-22 C- 1/5 3/5 1/5 1/5 2/5 1/5 1/5
2026-04-21 C- 1/5 3/5 1/5 1/5 2/5 1/5 1/5
2026-04-20 C- 1/5 3/5 1/5 1/5 2/5 1/5 1/5
2026-04-17 C- 1/5 3/5 1/5 1/5 2/5 1/5 1/5
2026-04-16 C- 1/5 3/5 1/5 1/5 2/5 1/5 1/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
-38.31M
OE per share TTM
-0.82
Owner's Yield
-7.89%
Maintenance CapEx ratio
Maint CapEx / Avg PPE
3,857.0%

Ownership Overview

Ownership breakdown
At a glance
Institutional holders
38
Total invested
26.92M
Insider transactions (90d)
0
Beneficial owners (>5%)
4
Beneficial owners (>5%)
# Reporting person Amount owned % of class Sole voting Shared voting Sole dispositive Shared dispositive Type Citizenship Filing date SEC filing
1 Paul B. Manning 4.07M 13.60% 2.97M 1.11M 2.97M 10.00 IN United States 2022-02-14
2 2 1.69M 5.90% 1.69M 1.69M PN 2022-02-14
3 The Paul B. Manning Revocable Trust dated May 10, 2000 1.28M 4.40% 1.28M 1.28M 10.00 OO Virginia 2022-02-14
4 BKB Growth Investments, LLC 1.11M 3.80% 1.11M 1.11M 10.00 OO Delaware 2022-02-14

Institutional Activity (13F)

Institutional ownership trend From To
13F snapshot — 2026 Q1
Investors holding
38
-50 vs prev Q
New positions
10
Closed positions
55
Increased
26
Reduced
6
Put/Call ratio
0.00
Calls held
Puts held
Top institutional holders
# Investor Shares / Δ Mkt value / Δ Own% / Δ Weight% / Δ Avg px / Perf. Hold / Status
1 FMR LLC 8.23M +914.0 (+0.0%) 46.52M +4.5M (+10.8%) 15.00% -0.990 pp 0.00% +0.000 pp USD7.01 -19.4% 6 qtrs
2 BLACKROCK, INC. 2.86M +482.4K (+20.3%) 16.17M +4.0M (+33.2%) 5.21% +0.592 pp 0.00% +0.000 pp USD6.09 -7.2% 6 qtrs
3 ACORN CAPITAL ADVISORS, LLC 2.58M +— (+0.0%) 14.58M +1.4M (+10.8%) 4.70% -0.311 pp 4.94% -1.741 pp USD7.83 -27.8% 5 qtrs
4 VANGUARD GROUP INC 2.31M +297.9K (+14.8%) 13.02M +2.8M (+27.2%) 4.20% +0.301 pp 0.00% +0.000 pp USD6.67 -15.3% 18 qtrs
5 PORTOLAN CAPITAL MANAGEMENT, LLC 1.70M +311.2K (+22.5%) 9.58M +2.5M (+35.7%) 3.09% +0.400 pp 0.51% +0.131 pp USD6.58 -14.1% 5 qtrs
6 GEODE CAPITAL MANAGEMENT, LLC 977.5K +49.3K (+5.3%) 5.52M +789.2K (+16.7%) 1.78% -0.022 pp 0.00% +0.000 pp USD5.73 -1.4% 18 qtrs
7 STATE STREET CORP 792.2K +103.5K (+15.0%) 4.48M +963.3K (+27.4%) 1.44% +0.106 pp 0.00% +0.000 pp USD6.39 -11.6% 18 qtrs
8 HALTER FERGUSON FINANCIAL INC. 748.1K +50.1K (+7.2%) 4.23M +666.7K (+18.7%) 1.36% +0.007 pp 0.93% +0.115 pp USD7.43 -24.0% 6 qtrs
9 SANDS CAPITAL VENTURES, LLC 405.8K +— (+0.0%) 2.29M +223.2K (+10.8%) 0.74% -0.049 pp 0.44% -0.011 pp USD10.84 -47.9% 18 qtrs
10 NORTHERN TRUST CORP 295.4K -11.3K (-3.7%) 1.67M +104.7K (+6.7%) 0.54% -0.058 pp 0.00% +0.000 pp USD6.12 -7.7% 17 qtrs
11 CITADEL ADVISORS LLC 226.4K -25.9K (-10.3%) 1.28M -7.8K (-0.6%) 0.41% -0.078 pp 0.00% +0.000 pp USD5.10 +10.8% 6 qtrs
12 TANAGER WEALTH MANAGEMENT LLP 198.2K +— (+0.0%) 1.12M +109.0K (+10.8%) 0.36% -0.024 pp 0.11% +0.006 pp USD5.06 +11.7% 3 qtrs
13 MORGAN STANLEY 134.0K +58.1K (+76.5%) 757.3K +370.0K (+95.5%) 0.24% +0.097 pp 0.00% +0.000 pp USD5.93 -4.7% 7 qtrs
14 JANE STREET GROUP, LLC 132.4K +22.0K (+19.9%) 748.1K +185.0K (+32.9%) 0.24% +0.027 pp 0.00% +0.000 pp USD5.87 -3.7% 5 qtrs
15 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 121.0K +— (+0.0%) 683.7K +66.6K (+10.8%) 0.22% -0.015 pp 0.00% +0.000 pp USD5.86 -3.6% 7 qtrs
16 UBS GROUP AG 104.3K +10.3K (+10.9%) 589.5K +109.8K (+22.9%) 0.19% +0.007 pp 0.00% +0.000 pp USD7.50 -24.7% 18 qtrs
17 TWO SIGMA INVESTMENTS, LP 99.2K -36.9K (-27.1%) 560.5K -133.7K (-19.3%) 0.18% -0.084 pp 0.00% 0.000 pp USD5.06 +11.7% 3 qtrs
18 BANK OF NEW YORK MELLON CORP 95.2K +639.0 (+0.7%) 537.9K +55.6K (+11.5%) 0.17% -0.010 pp 0.00% +0.000 pp USD5.75 -1.7% 7 qtrs
19 NUVEEN, LLC 92.5K -117.2K (-55.9%) 522.5K -546.8K (-51.1%) 0.17% -0.239 pp 0.00% 0.000 pp USD5.30 +6.6% 4 qtrs
20 COMMONWEALTH EQUITY SERVICES, LLC 82.3K +125.0 (+0.2%) 465.3K +46.3K (+11.0%) 0.15% -0.010 pp 0.00% +0.000 pp USD7.04 -19.7% 5 qtrs
21 COLONY GROUP, LLC 81.8K +81.8K (+100.0%) 462.3K +462.3K (+100.0%) 0.15% +0.149 pp 0.00% +0.001 pp USD5.65 +0.0% 1 qtrs NEW
22 WELLS FARGO & COMPANY/MN 73.9K +47.6K (+180.9%) 417.5K +283.3K (+211.2%) 0.13% +0.084 pp 0.00% +0.000 pp USD5.76 -1.9% 13 qtrs
23 SUSQUEHANNA INTERNATIONAL GROUP, LLP 73.0K -20.7K (-22.1%) 412.5K -65.4K (-13.7%) 0.13% -0.049 pp 0.00% +0.000 pp USD8.30 -31.9% 7 qtrs
24 BARCLAYS PLC 69.3K +40.7K (+141.7%) 391.8K +193.0K (+97.1%) 0.13% +0.071 pp 0.00% +0.000 pp USD5.79 -2.4% 7 qtrs
25 ALLIANCEBERNSTEIN L.P. 69.1K +— (+0.0%) 390.5K +38.0K (+10.8%) 0.13% -0.008 pp 0.00% +0.000 pp USD5.25 +7.6% 7 qtrs
26 66.8K +66.8K (+100.0%) 377.1K +377.1K (+100.0%) 0.12% +0.122 pp 0.13% +0.131 pp USD5.65 +0.0% 1 qtrs NEW
27 GOLDMAN SACHS GROUP INC 65.1K +29.1K (+80.7%) 367.7K +184.0K (+100.2%) 0.12% +0.049 pp 0.00% +0.000 pp USD6.33 -10.7% 7 qtrs
28 BIRCHVIEW CAPITAL, LP 60.0K +— (+0.0%) 339.0K +33.0K (+10.8%) 0.11% -0.007 pp 0.20% -0.033 pp USD8.68 -34.9% 5 qtrs
29 HB WEALTH MANAGEMENT, LLC 58.3K +— (+0.0%) 329.6K +32.1K (+10.8%) 0.11% -0.007 pp 0.00% +0.000 pp USD5.10 +10.8% 6 qtrs
30 BRIDGEWAY CAPITAL MANAGEMENT, LLC 55.1K +— (+0.0%) 311.3K +30.3K (+10.8%) 0.10% -0.007 pp 0.01% +0.001 pp USD5.06 +11.7% 16 qtrs
31 LIDO ADVISORS, LLC 60.2K +— (+0.0%) 307.0K +— (+0.0%) 0.11% -0.007 pp 0.00% +0.000 pp USD5.10 +10.8% 2 qtrs
32 STATE OF WISCONSIN INVESTMENT BOARD 52.1K -1.9K (-3.5%) 294.6K +19.0K (+6.9%) 0.10% -0.010 pp 0.00% +0.000 pp USD5.10 +10.8% 2 qtrs
33 BANK OF AMERICA CORP /DE/ 51.3K +3.6K (+7.6%) 289.7K +46.8K (+19.2%) 0.09% +0.001 pp 0.00% +0.000 pp USD6.43 -12.1% 9 qtrs
34 RHUMBLINE ADVISERS 51.0K -2.6K (-4.9%) 288.2K +14.6K (+5.3%) 0.09% -0.011 pp 0.00% +0.000 pp USD5.90 -4.2% 7 qtrs
35 ALPS ADVISORS INC 45.1K +18.8K (+71.5%) 254.7K +120.7K (+90.0%) 0.08% +0.031 pp 0.00% +0.001 pp USD5.31 +6.4% 3 qtrs
36 MONETA GROUP INVESTMENT ADVISORS LLC 42.5K +2.0K (+4.9%) 240.2K +33.6K (+16.3%) 0.08% -0.001 pp 0.00% +0.000 pp USD5.63 +0.4% 4 qtrs
37 MARTINGALE ASSET MANAGEMENT L P 37.5K +37.5K (+100.0%) 212.0K +212.0K (+100.0%) 0.07% +0.068 pp 0.01% +0.005 pp USD5.65 +0.0% 1 qtrs NEW
38 RAYMOND JAMES FINANCIAL INC 33.0K +10.8K (+48.9%) 186.5K +73.4K (+64.9%) 0.06% +0.017 pp 0.00% +0.000 pp USD5.65 +0.0% 4 qtrs
39 LPL FINANCIAL LLC 28.7K +7.3K (+33.9%) 161.9K +52.7K (+48.3%) 0.05% +0.011 pp 0.00% +0.000 pp USD5.21 +8.4% 5 qtrs
40 DEUTSCHE BANK AG\ 28.4K +1.7K (+6.4%) 160.3K +24.4K (+17.9%) 0.05% 0.000 pp 0.00% +0.000 pp USD7.84 -27.9% 7 qtrs
41 JANNEY MONTGOMERY SCOTT LLC 27.1K -3.3K (-10.9%) 153.0K -2.0K (-1.3%) 0.05% -0.010 pp 0.00% +0.000 pp USD5.70 -0.9% 7 qtrs
42 VIRTU FINANCIAL LLC 26.8K +26.8K (+100.0%) 152.0K +152.0K (+100.0%) 0.05% +0.049 pp 0.01% +0.006 pp USD5.65 +0.0% 1 qtrs NEW
43 PRICE T ROWE ASSOCIATES INC /MD/ 25.8K +6.2K (+31.4%) 146.0K +45.0K (+44.6%) 0.05% +0.009 pp 0.00% +0.000 pp USD5.48 +3.1% 4 qtrs
44 KRILOGY FINANCIAL LLC 24.0K +24.0K (+100.0%) 144.2K +144.2K (+100.0%) 0.04% +0.044 pp 0.00% +0.005 pp USD5.65 +0.0% 1 qtrs NEW
45 XTX TOPCO LTD 23.8K +23.8K (+100.0%) 134.3K +134.3K (+100.0%) 0.04% +0.043 pp 0.00% +0.004 pp USD5.65 +0.0% 3 qtrs
46 STRATOS WEALTH ADVISORS, LLC 23.0K +— (+0.0%) 130.0K +12.7K (+10.8%) 0.04% -0.003 pp 0.01% +0.001 pp USD5.65 +0.0% 4 qtrs
47 JPMORGAN CHASE & CO 21.6K +3.8K (+21.3%) 122.2K +31.2K (+34.3%) 0.04% +0.005 pp 0.00% +0.000 pp USD5.92 -4.6% 11 qtrs
48 MIRAE ASSET GLOBAL ETFS HOLDINGS LTD. 20.0K +538.0 (+2.8%) 113.0K +13.7K (+13.8%) 0.04% -0.001 pp 0.00% +0.000 pp USD6.33 -10.7% 6 qtrs
49 SQUAREPOINT OPS LLC 19.7K -11.2K (-36.3%) 111.5K -46.4K (-29.4%) 0.04% -0.024 pp 0.00% +0.000 pp USD6.10 -7.4% 7 qtrs
50 METLIFE INVESTMENT MANAGEMENT, LLC 19.4K +4.0K (+25.5%) 109.9K +30.9K (+39.1%) 0.04% +0.005 pp 0.00% +0.000 pp USD6.08 -7.1% 6 qtrs
51 INTECH INVESTMENT MANAGEMENT LLC 17.8K -2.7K (-13.2%) 100.7K -4.1K (-3.9%) 0.03% -0.007 pp 0.00% +0.000 pp USD5.65 +0.0% 4 qtrs
52 BOREAL CAPITAL MANAGEMENT LLC 16.0K +— (+0.0%) 90.4K +8.8K (+10.8%) 0.03% -0.002 pp 0.08% +0.005 pp USD5.06 +11.7% 3 qtrs
53 INVESCO LTD. 15.0K +3.4K (+29.0%) 85.0K +25.5K (+42.9%) 0.03% +0.005 pp 0.00% +0.000 pp USD5.60 +0.9% 4 qtrs
54 MANUFACTURERS LIFE INSURANCE COMPANY, THE 13.6K -121.0 (-0.9%) 76.9K +6.9K (+9.8%) 0.02% -0.002 pp 0.00% +0.000 pp USD5.06 +11.7% 3 qtrs
55 TAYLOR FINANCIAL GROUP, INC. 13.6K +— (+0.0%) 76.8K +7.5K (+10.8%) 0.02% -0.002 pp 0.05% +0.005 pp USD5.50 +2.7% 4 qtrs
56 QUEST PARTNERS LLC 11.9K +— (+0.0%) 67.5K +6.6K (+10.8%) 0.02% -0.001 pp 0.00% 0.000 pp USD5.60 +0.9% 4 qtrs
57 POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY 11.2K +— (+0.0%) 63.3K +6.2K (+10.8%) 0.02% -0.001 pp 0.00% +0.000 pp USD6.83 -17.3% 5 qtrs
58 PROSHARE ADVISORS LLC 10.4K +10.4K (+100.0%) 58.9K +58.9K (+100.0%) 0.02% +0.019 pp 0.00% +0.000 pp USD5.65 +0.0% 1 qtrs NEW
59 BNP PARIBAS ARBITRAGE, SNC 9.9K +2.0K (+25.7%) 56.1K +15.8K (+39.3%) 0.02% +0.003 pp 0.00% +0.000 pp USD5.70 -0.9% 5 qtrs
60 CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD. 8.9K +8.9K (+100.0%) 50.5K +50.5K (+100.0%) 0.02% +0.016 pp 0.00% +0.004 pp USD5.65 +0.0% 1 qtrs NEW
61 GROUP ONE TRADING, L.P. 8.9K +8.9K (+100.0%) 50.3K +50.3K (+100.0%) 0.02% +0.016 pp 0.00% +0.000 pp USD5.65 +0.0% 1 qtrs NEW
62 ADVISOR GROUP HOLDINGS, INC. 6.5K -8.4K (-56.4%) 36.6K -49.4K (-57.4%) 0.01% -0.017 pp 0.00% 0.000 pp USD6.07 -6.9% 7 qtrs
63 LEGAL & GENERAL GROUP PLC 4.2K +— (+0.0%) 23.9K +2.3K (+10.8%) 0.01% -0.001 pp 0.00% +0.000 pp USD5.80 -2.6% 7 qtrs
64 RUSSELL INVESTMENTS GROUP, LTD. 4.2K +905.0 (+27.8%) 23.5K +6.9K (+41.6%) 0.01% +0.001 pp 0.00% +0.000 pp USD5.22 +8.2% 6 qtrs
65 AMERITAS INVESTMENT PARTNERS, INC. 4.0K +— (+0.0%) 22.7K +2.2K (+10.8%) 0.01% -0.001 pp 0.00% +0.000 pp USD5.66 -0.2% 7 qtrs
66 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 2.7K +243.0 (+9.9%) 15.2K +2.7K (+21.7%) 0.00% +0.000 pp 0.00% +0.000 pp USD6.01 -6.0% 7 qtrs
67 CITIGROUP INC 2.7K +963.0 (+56.3%) 15.1K +6.4K (+73.1%) 0.00% +0.002 pp 0.00% +0.000 pp USD6.54 -13.6% 7 qtrs
68 MIRAE ASSET GLOBAL INVESTMENTS CO., LTD. 2.7K +2.7K (+100.0%) 15.1K +15.1K (+100.0%) 0.00% +0.005 pp 0.00% +0.000 pp USD5.65 +0.0% 1 qtrs NEW
69 TOWER RESEARCH CAPITAL LLC (TRC) 1.9K -3.8K (-66.6%) 10.6K -18.1K (-63.0%) 0.00% -0.008 pp 0.00% -0.001 pp USD5.06 +11.7% 15 qtrs
70 ROYAL BANK OF CANADA 1.8K +851.0 (+85.6%) 10.0K +5.0K (+100.0%) 0.00% +0.001 pp 0.00% +0.000 pp USD5.41 +4.4% 7 qtrs
71 NEW YORK STATE COMMON RETIREMENT FUND 1.7K +— (+0.0%) 9.6K +935.0 (+10.8%) 0.00% 0.000 pp 0.00% +0.000 pp USD6.30 -10.3% 7 qtrs
72 CLOSE ASSET MANAGEMENT LTD 1.4K +— (+0.0%) 8.0K +1.0K (+14.3%) 0.00% 0.000 pp 0.00% +0.000 pp USD5.06 +11.7% 3 qtrs
73 AMALGAMATED BANK 1.4K +397.0 (+40.5%) 8.0K +3.0K (+60.0%) 0.00% +0.001 pp 0.00% +0.000 pp USD5.97 -5.4% 7 qtrs
74 GF FUND MANAGEMENT CO. LTD. 1.1K +1.1K (+100.0%) 6.1K +6.1K (+100.0%) 0.00% +0.002 pp 0.00% +0.000 pp USD5.65 +0.0% 1 qtrs NEW
75 JONES FINANCIAL COMPANIES LLLP 1.0K -310.0 (-23.3%) 5.8K -1.6K (-21.8%) 0.00% -0.001 pp 0.00% +0.000 pp USD5.29 +6.8% 4 qtrs
76 OPTIVER HOLDING B.V. 656.00 +— (+0.0%) 3.7K +360.0 (+10.8%) 0.00% 0.000 pp 0.00% +0.000 pp USD5.10 +10.8% 2 qtrs
77 STERLING CAPITAL MANAGEMENT LLC 510.00 +156.0 (+44.1%) 2.9K +1.1K (+59.7%) 0.00% +0.000 pp 0.00% +0.000 pp USD5.35 +5.6% 6 qtrs
78 GAMMA INVESTING LLC 295.00 +96.0 (+48.2%) 1.7K +652.0 (+64.2%) 0.00% +0.000 pp 0.00% +0.000 pp USD5.42 +4.2% 6 qtrs
79 NISA INVESTMENT ADVISORS, LLC 48.00 +— (+0.0%) 271.00 +26.0 (+10.6%) 0.00% +0.000 pp 0.00% +0.000 pp USD6.19 -8.7% 6 qtrs
80 SBI SECURITIES CO., LTD. 20.00 -1.0 (-4.8%) 113.00 +6.0 (+5.6%) 0.00% +0.000 pp 0.00% +0.000 pp USD6.70 -15.7% 5 qtrs
81 SUNBELT SECURITIES, INC. 16.00 -11.0 (-40.7%) 90.00 -48.0 (-34.8%) 0.00% +0.000 pp 0.00% +0.000 pp USD5.06 +11.7% 2 qtrs
82 PNC FINANCIAL SERVICES GROUP, INC. 5.00 -59.0 (-92.2%) 28.00 -298.0 (-91.4%) 0.00% 0.000 pp 0.00% +0.000 pp USD5.00 +13.0% 2 qtrs
83 CAITONG INTERNATIONAL ASSET MANAGEMENT CO., LTD 1.00 +1.0 (+100.0%) 6.00 +6.0 (+100.0%) 0.00% +0.000 pp 0.00% +0.000 pp USD5.00 +13.0% 5 qtrs
84 ENTRYPOINT CAPITAL, LLC -18.7K (-100.0%) -95.4K (-100.0%) 0.00% -0.036 pp 0.00% -0.037 pp USD 4 qtrs SOLD
85 QUADRATURE CAPITAL LTD -13.8K (-100.0%) -70.5K (-100.0%) 0.00% -0.027 pp 0.00% -0.001 pp USD 2 qtrs SOLD
86 QUARRY LP -4.2K (-100.0%) -21.4K (-100.0%) 0.00% -0.008 pp 0.00% -0.005 pp USD 2 qtrs SOLD
87 MILLENNIUM MANAGEMENT LLC -136.7K (-100.0%) -697.0K (-100.0%) 0.00% -0.265 pp 0.00% 0.000 pp USD 7 qtrs SOLD
88 MARSHALL WACE, LLP -103.8K (-100.0%) -529.6K (-100.0%) 0.00% -0.202 pp 0.00% -0.001 pp USD 4 qtrs SOLD
89 SRS CAPITAL ADVISORS, INC. -54.0 (-100.0%) -275.0 (-100.0%) 0.00% 0.000 pp 0.00% +0.000 pp USD 2 qtrs SOLD
90 KOVITZ INVESTMENT GROUP PARTNERS, LLC -79.3K (-100.0%) -404.5K (-100.0%) 0.00% -0.154 pp 0.00% -0.002 pp USD 2 qtrs SOLD
91 BALYASNY ASSET MANAGEMENT L.P. -49.5K (-100.0%) -252.4K (-100.0%) 0.00% -0.096 pp 0.00% 0.000 pp USD 4 qtrs SOLD
92 CWM, LLC -196.0 (-100.0%) -1.0K (-100.0%) 0.00% 0.000 pp 0.00% +0.000 pp USD 4 qtrs SOLD
93 WELLINGTON MANAGEMENT GROUP LLP -137.9K (-100.0%) -703.2K (-100.0%) 0.00% -0.268 pp 0.00% 0.000 pp USD 3 qtrs SOLD
94 EVERSOURCE WEALTH ADVISORS, LLC -86.0 (-100.0%) -439.0 (-100.0%) 0.00% 0.000 pp 0.00% +0.000 pp USD 4 qtrs SOLD
Ownership breakdown by holder

ETF Ownership

Top ETFs holding this stock Held by 64 ETFs in our universe
# ETF Weight Est. AUM exposure TER
1 Virtus Biotech Clinical Trials ETF BBC 0.68% 392.8K 0.65%
2 ALPS Medical Breakthroughs ETF SBIO 0.36% 759.3K 0.50%
3 Global X - S&P Biotech ETF CURE.AX 0.18% 64.1K 0.45%
4 State Street SPDR S&P Biotech ETF XBI 0.18% 19.26M 0.35%
5 iShares Micro-Cap ETF IWC 0.14% 2.01M 0.60%
6 State Street SPDR S&P Kensho New Economies Composite ETF KOMP 0.09% 2.50M 0.20%
7 iShares Nasdaq US Biotechnology UCITS ETF BTEE.L 0.05% 35.9K 0.35%
8 iShares Nasdaq US Biotechnology UCITS ETF BTEC.L 0.05% 536.8K 0.35%
9 Invesco NASDAQ Biotech UCITS ETF SBIO.L 0.05% 221.2K 0.40%
10 Invesco Nasdaq Biotechnology ETF IBBQ 0.05% 35.7K 0.19%

Insider Activity

Insider Activity — Latest Quarter
Ratio by transactions
0.00
Bearish
Buys
9
Sells
0
Shares acquired
1.94M
Shares disposed
Cash buys
1.00
Cash sales
Net activity
+1,942,150
Insider buys vs sells (history) From To
Recent insider transactions From To
Date Person Role Transaction A/D Security Shares Price Value Owned after D/I Filing
2026-03-31 PAPA JOSEPH C Director A-Award A Stock Option (Right to Buy) 2,795 4.90 13.7K 2,795 D
2026-03-31 Manning Paul B Director A-Award A Stock Option (Right to Buy) 4,618 4.90 22.6K 4,618 D
2026-03-31 Loggia Nicoletta Director A-Award A Stock Option (Right to Buy) 779 4.90 3.8K 779 D
2026-02-23 Manning Paul B Director P-Purchase A Common Stock 550,458 5.45 3.00M 2,763,527 I
2026-01-26 Tyagarajan Seshu Officer A-Award A Stock Option (Right to Buy) 154,000 6.01 925.5K 154,000 D
2026-01-26 Tak Paul Peter Director / Officer A-Award A Stock Option (Right to Buy) 629,000 6.01 3.78M 629,000 D
2026-01-26 Schoch Charles Officer A-Award A Stock Option (Right to Buy) 232,000 6.01 1.39M 232,000 D
2026-01-26 Nichols William Garrett Officer A-Award A Stock Option (Right to Buy) 136,500 6.01 820.4K 136,500 D
2026-01-26 Barone Francesca Officer A-Award A Stock Option (Right to Buy) 232,000 6.01 1.39M 232,000 D
2025-07-28 Nichols William Garrett Officer M-Exempt A Common Stock 937 1.29 1.2K 53,430 D
2025-06-30 Nichols William Garrett Officer M-Exempt D Stock Option (Right to Buy) 781 1.29 1.0K 30,314 D
2025-06-25 Tyagarajan Seshu Officer A-Award A Common Stock 5,353 4.67 25.0K 90,865 D
2025-06-25 Tak Paul Peter Director / Officer A-Award A Common Stock 42,826 4.67 200.0K 268,566 D
2025-06-25 Schoch Charles Officer A-Award A Common Stock 5,353 4.67 25.0K 43,391 D
2025-06-25 PAPA JOSEPH C Director A-Award A Common Stock 64,239 4.67 300.0K 64,239 I
2025-06-25 Nabel Gary J. Director A-Award A Common Stock 5,353 4.67 25.0K 5,353 D
2025-06-25 Martell Christopher Director A-Award A Common Stock 111,349 4.67 520.0K 111,349 I
2025-06-25 Manning Paul B Director A-Award A Common Stock 1,070,663 4.67 5.00M 2,213,069 I
2025-06-25 Loggia Nicoletta Director A-Award A Common Stock 2,141 4.67 10.0K 2,141 D
2025-06-25 Barone Francesca Officer A-Award A Common Stock 4,282 4.67 20.0K 100,809 D
2025-06-20 Schoch Charles Officer A-Award A Stock Option (Right to Buy) 50,000 4.75 237.5K 50,000 D
2025-06-17 PAPA JOSEPH C Director A-Award A Stock Option (Right to Buy) 14,240 4.94 70.3K 14,240 D
2025-06-17 Nguyen Diem Director A-Award A Stock Option (Right to Buy) 14,240 4.94 70.3K 14,240 D
2025-06-17 Nabel Gary J. Director A-Award A Stock Option (Right to Buy) 14,240 4.94 70.3K 14,240 D
2025-06-17 Martell Christopher Director A-Award A Stock Option (Right to Buy) 14,240 4.94 70.3K 14,240 D
2025-06-17 Manning Paul B Director A-Award A Stock Option (Right to Buy) 14,240 4.94 70.3K 14,240 D
2025-06-17 Loggia Nicoletta Director A-Award A Stock Option (Right to Buy) 14,240 4.94 70.3K 14,240 D
2025-06-17 Gaeta Renee Director A-Award A Stock Option (Right to Buy) 14,240 4.94 70.3K 14,240 D
2025-06-17 Benz Edward J. JR Director A-Award A Stock Option (Right to Buy) 14,240 4.94 70.3K 14,240 D
2025-06-04 Radhakrishnan Maha Director A-Award A Stock Option (Right to Buy) 28,480 5.60 159.5K 28,480 D
2025-03-19 Tak Paul Peter Director / Officer S-Sale D Common Stock 400 9.00 3.6K 225,740 D
2025-03-18 Tak Paul Peter Director / Officer S-Sale D Common Stock 25,772 8.77 226.0K 226,140 D
2025-03-18 Nichols William Garrett Officer M-Exempt A Common Stock 4,584 3.75 17.2K 83,904 D
2025-03-18 Barone Francesca Officer M-Exempt A Common Stock 18,000 1.55 27.9K 128,673 D
2025-03-17 Tyagarajan Seshu Officer M-Exempt D Stock Option (Right to Buy) 20,000 1.29 25.8K 70,000 D
2025-03-17 Schoch Charles Officer S-Sale D Common Stock 5,000 8.83 44.2K 38,038 D
2025-02-21 Aguilar-Cordova Estuardo 10% Owner D-Return D CADL 10,583 12.02 127.2K 162,929 D
2025-02-12 Tyagarajan Seshu Officer A-Award A Stock Option (Right to Buy) 65,000 8.55 555.8K 65,000 D
2025-02-12 Tak Paul Peter Director / Officer A-Award A Stock Option (Right to Buy) 525,000 8.55 4.49M 525,000 D
2025-02-12 Schoch Charles Officer A-Award A Stock Option (Right to Buy) 83,000 8.55 709.7K 83,000 D
2025-02-12 Nichols William Garrett Officer A-Award A Stock Option (Right to Buy) 107,250 8.55 917.0K 107,250 D
2025-02-12 Barone Francesca Officer A-Award A Stock Option (Right to Buy) 115,000 8.55 983.3K 115,000 D
2025-02-10 Aguilar-Cordova Estuardo 10% Owner D-Return D CADL 31,335 8.61 269.8K 60,000 D
2025-01-15 Tyagarajan Seshu Officer S-Sale D Common Stock 14,322 7.23 103.5K 96,790 D
2025-01-15 Tak Paul Peter Director / Officer S-Sale D Common Stock 21,704 7.23 156.8K 251,912 D
2025-01-15 Schoch Charles Officer S-Sale D Common Stock 9,511 7.23 68.7K 43,038 D
2025-01-15 Nichols William Garrett Officer S-Sale D Common Stock 10,428 7.23 75.3K 79,320 D
2025-01-15 Barone Francesca Officer S-Sale D Common Stock 13,534 7.23 97.8K 110,673 D
2025-01-08 Tyagarajan Seshu Officer S-Sale D Common Stock 14,545 8.22 119.5K 111,112 D
2025-01-08 Tak Paul Peter Director / Officer S-Sale D Common Stock 21,172 8.22 174.0K 273,616 D
2025-01-08 Schoch Charles Officer S-Sale D Common Stock 9,971 8.22 81.9K 52,549 D
2025-01-08 Nichols William Garrett Officer S-Sale D Common Stock 10,799 8.22 88.7K 89,748 D
2025-01-08 Barone Francesca Officer S-Sale D Common Stock 13,673 8.22 112.4K 124,207 D
2024-12-27 Aguilar-Cordova Estuardo 10% Owner D-Return D CADL 50,000 8.85 442.5K 173,512 D
2024-12-26 Aguilar-Cordova Estuardo 10% Owner D-Return D CADL 50,000 9.01 450.5K 223,512 D
2024-12-24 Aguilar-Cordova Estuardo 10% Owner D-Return A CADL 50,000 8.82 441.0K 273,512 D
2024-12-23 Aguilar-Cordova Estuardo 10% Owner D-Return D CADL 50,000 8.52 426.0K 323,512 D
2024-12-20 Aguilar-Cordova Estuardo 10% Owner D-Return D CADL 100,000 9.00 900.0K 373,512 D
2024-12-16 Manning Paul B Director P-Purchase A Common Stock 750,000 6.00 4.50M 1,303,752 I
2024-12-12 Aguilar-Cordova Estuardo 10% Owner D-Return D CADL 200,000 10.04 2.01M 473,512 D
2024-12-11 Aguilar-Cordova Estuardo 10% Owner D-Return D CADL 200,000 8.53 1.71M 631,443 I
2024-12-06 Aguilar-Cordova Estuardo 10% Owner D-Return D CADL 20,000 5.23 104.6K 91,335 D
2024-12-05 Aguilar-Cordova Estuardo 10% Owner D-Return D CADL 20,000 4.79 95.8K 111,335 D
2024-12-04 Aguilar-Cordova Estuardo 10% Owner D-Return D CADL 20,000 4.46 89.2K 131,335 D
2024-11-29 Tyagarajan Seshu Officer S-Sale D Common Stock 20,392 4.56 92.9K 125,657 D
2024-11-29 Tak Paul Peter Director / Officer S-Sale D Common Stock 48,847 4.56 222.5K 294,788 D
2024-11-29 Nichols William Garrett Officer S-Sale D Common Stock 13,935 4.56 63.5K 100,547 D
2024-11-29 Barone Francesca Officer S-Sale D Common Stock 22,081 4.56 100.6K 137,880 D
2024-11-25 Aguilar-Cordova Estuardo 10% Owner D-Return D CADL 20,000 4.97 99.4K 151,335 D
2024-11-21 Tak Paul Peter Director / Officer M-Exempt D Stock Option (Right to Buy) 12,900 1.55 20.0K 1,763,968 D
2024-11-08 Aguilar-Cordova Estuardo 10% Owner D-Return D CADL 7,500 4.92 36.9K 831,443 I
2024-11-07 Aguilar-Cordova Estuardo 10% Owner D-Return D CADL 7,500 5.19 38.9K 881,012 D
2024-11-06 Aguilar-Cordova Estuardo 10% Owner D-Return D CADL 7,500 5.33 40.0K 846,443 I
2024-11-01 Aguilar-Cordova Estuardo 10% Owner D-Return D CADL 7,500 5.27 39.5K 896,012 D
2024-10-31 Aguilar-Cordova Estuardo 10% Owner D-Return D CADL 7,500 5.30 39.8K 903,512 D
2024-10-30 Aguilar-Cordova Estuardo 10% Owner D-Return D CADL 6,000 5.38 32.3K 911,012 D
2024-10-28 Aguilar-Cordova Estuardo 10% Owner D-Return D CADL 11,711 5.58 65.3K 888,532 D
2024-10-25 Aguilar-Cordova Estuardo 10% Owner D-Return D CADL 1,597 5.80 9.3K 900,243 D
2024-10-24 Aguilar-Cordova Estuardo 10% Owner D-Return D CADL 16,427 5.53 90.8K 903,034 D
2024-10-15 Aguilar-Cordova Estuardo 10% Owner S-Sale D CADL 10,412 6.03 62.8K 919,461 D
2024-10-14 Aguilar-Cordova Estuardo 10% Owner S-Sale D CADL 15,000 6.02 90.3K 929,873 D
2024-10-11 Aguilar-Cordova Estuardo 10% Owner S-Sale D CADL 15,000 6.05 90.8K 944,873 D
2024-10-03 Aguilar-Cordova Estuardo 10% Owner S-Sale D CADL 1,800 6.85 12.3K 959,873 D
2024-10-02 Aguilar-Cordova Estuardo 10% Owner S-Sale D CADL 26,988 6.92 186.8K 961,673 D
2024-10-01 Aguilar-Cordova Estuardo 10% Owner S-Sale A CADL 6,214 7.01 43.6K 988,661 D
2024-07-17 Tyagarajan Seshu Officer S-Sale D Common Stock 14,851 6.47 96.1K 146,049
2024-07-17 Tak Paul Peter Director / Officer S-Sale D Common Stock 22,528 6.47 145.8K 330,735
2024-07-17 Schoch Charles Officer S-Sale D Common Stock 9,884 6.47 64.0K 62,520
2024-07-17 Nichols William Garrett Officer S-Sale D Common Stock 10,875 6.47 70.4K 114,482
2024-07-17 Barone Francesca Officer S-Sale D Common Stock 14,051 6.47 90.9K 159,961
2024-07-11 Tyagarajan Seshu Officer S-Sale D Common Stock 13,330 5.97 79.6K 160,900
2024-07-11 Tak Paul Peter Director / Officer S-Sale D Common Stock 20,293 5.97 121.2K 353,263
2024-07-11 Schoch Charles Officer S-Sale D Common Stock 8,897 5.97 53.1K 72,404
2024-07-11 Nichols William Garrett Officer S-Sale D Common Stock 9,769 5.97 58.4K 125,357
2024-07-11 Barone Francesca Officer S-Sale D Common Stock 12,645 5.97 75.5K 174,012
2024-06-26 PAPA JOSEPH C Director A-Award A Stock Option (Right to Buy) 14,240 5.71 81.3K 14,240
2024-06-26 Nguyen Diem Director A-Award A Stock Option (Right to Buy) 14,240 5.71 81.3K 14,240
2024-06-26 Nabel Gary J. Director A-Award A Stock Option (Right to Buy) 14,240 5.71 81.3K 14,240
2024-06-26 Martell Christopher Director A-Award A Stock Option (Right to Buy) 14,240 5.71 81.3K 14,240
2024-06-26 Manning Paul B Director A-Award A Stock Option (Right to Buy) 14,240 5.71 81.3K 14,240
2024-06-26 Loggia Nicoletta Director A-Award A Stock Option (Right to Buy) 14,240 5.71 81.3K 14,240
2024-06-26 Gaeta Renee Director A-Award A Stock Option (Right to Buy) 14,240 5.71 81.3K 14,240
2024-06-26 Benz Edward J. JR Director A-Award A Stock Option (Right to Buy) 14,240 5.71 81.3K 14,240
2024-01-12 Schoch Charles Officer D Common Stock 0 0.00 79,301
2023-11-28 Tyagarajan Seshu Officer F-InKind D Common Stock 17,328 0.90 15.6K 174,230
2023-11-28 Tak Paul Peter Director / Officer F-InKind D Common Stock 43,443 0.90 39.1K 373,556
2023-11-28 Nichols William Garrett Officer F-InKind D Common Stock 12,175 0.90 11.0K 135,126
2023-11-28 Barone Francesca Officer F-InKind D Common Stock 19,748 0.90 17.8K 186,657
2023-11-28 Amello Jason Officer F-InKind D Common Stock 20,153 0.90 18.1K 202,009
2023-11-26 Tyagarajan Seshu Officer A-Award A Common Stock 104,516 0.00 191,558
2023-11-26 Tak Paul Peter Director / Officer A-Award A Common Stock 180,108 0.00 416,999
2023-11-26 Nichols William Garrett Officer A-Award A Common Stock 88,822 0.00 147,301
2023-11-26 Barone Francesca Officer A-Award A Common Stock 112,790 0.00 206,405
2023-11-26 Amello Jason Officer A-Award A Common Stock 125,717 0.00 222,162
2023-06-28 PAPA JOSEPH C Director A-Award A Stock Option (Right to Buy) 14,240 1.22 17.4K 14,240
2023-06-28 Nguyen Diem Director A-Award A Stock Option (Right to Buy) 14,240 1.22 17.4K 14,240
2023-06-28 Nabel Gary J. Director A-Award A Stock Option (Right to Buy) 14,240 1.22 17.4K 14,240
2023-06-28 Martell Christopher Director A-Award A Stock Option (Right to Buy) 14,240 1.22 17.4K 14,240
2023-06-28 Manning Paul B Director A-Award A Stock Option (Right to Buy) 14,240 1.22 17.4K 14,240
2023-06-28 Gaeta Renee Director A-Award A Stock Option (Right to Buy) 14,240 1.22 17.4K 14,240
2023-06-28 Benz Edward J. JR Director A-Award A Stock Option (Right to Buy) 14,240 1.22 17.4K 14,240
2023-06-28 Aguilar-Cordova Estuardo Director A-Award A Stock Option (Right to Buy) 14,240 1.22 17.4K 14,240
2023-06-07 Loggia Nicoletta Director 0 0.00 0
2023-04-28 Tyagarajan Seshu Officer A-Award A Stock Option (Right to Buy) 90,000 1.29 116.1K 90,000
2023-04-28 Tak Paul Peter Director / Officer A-Award A Stock Option (Right to Buy) 180,000 1.29 232.2K 180,000
2023-04-28 Nichols William Garrett Officer A-Award A Stock Option (Right to Buy) 45,000 1.29 58.1K 45,000
2023-04-28 Barone Francesca Officer A-Award A Stock Option (Right to Biuy) 90,000 1.29 116.1K 90,000
2023-04-28 Amello Jason Officer A-Award A Stock Option (Right to Buy) 90,000 1.29 116.1K 90,000
2022-12-09 Tyagarajan Seshu Officer P-Purchase A Common Stock 10,358 1.93 20.0K 13,358
2022-12-09 Tak Paul Peter Officer P-Purchase A Common Stock 12,935 1.92 24.8K 40,985
2022-12-09 PAPA JOSEPH C Director P-Purchase A Common Stock 35,018 1.94 67.9K 38,032
2022-12-09 Martell Christopher Director P-Purchase A Common Stock 23,950 1.92 46.0K 152,000 D
2022-12-09 Amello Jason Officer P-Purchase A Common Stock 2,468 1.93 4.8K 5,568
2022-12-08 Tyagarajan Seshu Officer P-Purchase A Common Stock 3,000 1.69 5.1K 3,000
2022-12-08 Tak Paul Peter Officer P-Purchase A Common Stock 3,050 1.70 5.2K 28,050
2022-12-08 PAPA JOSEPH C Director P-Purchase A Common Stock 3,014 1.70 5.1K 3,014
2022-12-08 Martell Christopher Director P-Purchase A Common Stock 3,050 1.68 5.1K 128,050 D
2022-12-08 Barone Francesca Officer P-Purchase A Common Stock 1,238 1.61 2.0K 2,738
2022-12-08 Amello Jason Officer P-Purchase A Common Stock 3,100 1.69 5.2K 3,100
2022-11-28 Tyagarajan Seshu Officer A-Award A Common Stock 73,684 0.00 73,684
2022-11-28 Tak Paul Peter Officer A-Award A Common Stock 195,906 0.00 220,906
2022-11-28 Nichols William Garrett Officer A-Award A Common Stock 58,479 0.00 58,479
2022-11-28 Barone Francesca Officer A-Award A Common Stock 90,877 0.00 92,377
2022-11-28 Amello Jason Officer A-Award A Common Stock 90,877 0.00 90,877
2022-10-13 Nguyen Diem Director A-Award A Stock Option (Right to Buy) 14,240 0.00 14,240
2022-10-13 Martell Christopher Director A-Award A Stock Option (Right to Buy) 14,240 0.00 14,240
2022-10-13 Manning Paul B Director A-Award A Stock Option (Right to Buy) 14,240 0.00 14,240
2022-10-13 Benz Edward J. JR Director A-Award A Stock Option (Right to Buy) 14,240 0.00 14,240
2022-10-13 Aguilar-Cordova Estuardo Director A-Award A Stock Option (Right to Buy) 14,240 0.00 14,240
2022-09-21 Amello Jason Officer A-Award A Stock Option (Right to Buy) 230,000 3.21 738.3K 230,000
2022-09-12 Nichols William Garrett Officer 0 0.00 0
2022-08-08 PAPA JOSEPH C Director A-Award A Stock Option (Right to Buy) 28,480 0.00 28,480
2022-08-08 Nabel Gary J. Director 0 0.00 0
2022-08-08 Gaeta Renee Director 0 0.00 0
2022-05-06 Aguilar-Cordova Estuardo Director F-InKind D Common Stock 54,074 3.65 197.4K 1,097,032
2022-05-06 Aguilar Laura K. Director F-InKind D Common Stock 68,534 3.65 250.1K 1,033,840
2022-04-14 Tyagarajan Seshu Officer A-Award A Stock Option (Right to Buy) 120,000 0.00 120,000
2022-04-11 Stewart Susan B. Officer A-Award A Stock Option (Right to Buy) 20,000 0.00 20,000
2022-02-28 Tak Paul Peter Director / Officer A-Award A Stock Option (Right to Buy) 330,000 4.12 1.36M 330,000
2022-02-28 Canepa John J Officer A-Award A Stock Option (Right to Buy) 110,000 4.12 453.2K 110,000
2022-02-28 Barone Francesca Officer A-Award A Stock Option (Right to Buy) 110,000 4.12 453.2K 110,000
2022-02-03 Barone Francesca Officer A-Award A Stock Option (Right to Buy) 40,000 4.06 162.4K 40,000
2021-12-31 Manning Paul B Director / 10% Owner D Common Stock 0 0.00 1,681,000
2021-07-29 Tak Paul Peter Director / Officer P-Purchase A Common Stock 25,000 8.00 200.0K 25,000
2021-07-29 Nguyen Diem Director P-Purchase A Common Stock 10,000 8.00 80.0K 10,000
2021-07-29 Martell Christopher Director C-Conversion D Series B Preferred Stock 696,851 0.00 0
2021-07-29 Manning Paul B Director C-Conversion D Series B Preferred Stock 1,361,069 0.00 0
2021-07-29 Canepa John J Officer P-Purchase A Common Stock 10,125 8.00 81.0K 10,125
2021-07-29 Caffo Nathan Officer P-Purchase A Common Stock 6,000 8.00 48.0K 6,000
2021-07-29 Aguilar-Cordova Estuardo Director / Officer C-Conversion A Common Stock 162,137 0.00 1,015,923
2021-07-29 Aguilar Laura K. Officer C-Conversion D Series B Preferred Stock 137,881 0.00 0
2021-07-27 Manning Paul B Director P-Purchase A Common Stock 36,000 7.36 264.8K 36,000
2021-07-26 Tak Paul Peter Director / Officer D Stock Option (Right to Buy) 1,776,868 1.55 2.75M 0
2021-07-26 Stewart Susan B. Officer D Stock Option (Right to Buy) 33,419 1.55 51.8K 0
2021-07-26 SMITH ALAN E Director D Common Stock 0 0.00 32,548
2021-07-26 Nguyen Diem Director A-Award A Stock Option (Right to Buy) 28,480 8.00 227.8K 28,480
2021-07-26 Meirav Udi Director D Stock Option (Right to Buy) 71,198 1.46 103.9K 0
2021-07-26 Martell Christopher Director D Stock Option (Right to Buy) 16,274 6.64 108.1K 0
2021-07-26 Manning Paul B Director I Series B Preferred Stock 553,752 0.00 0
2021-07-26 Gandhi Shaan-Chirag C Director 0 0.00 0
2021-07-26 Canepa John J Officer D Stock Option (Right to Buy) 322,710 1.55 500.2K 0
2021-07-26 Caffo Nathan Officer D Stock Option (Right to Buy) 296,144 1.55 459.0K 0
2021-07-26 Benz Edward J. JR Director D Stock Option (Right to Buy) 4,068 1.46 5.9K 0
2021-07-26 Aguilar-Cordova Estuardo Director / Officer D Series B Preferred Stock 162,137 0.00 0
2021-07-26 Aguilar Laura K. Officer D Series B Preferred Stock 56,096 0.00 0
2018-12-31 Martell Christopher Director I Warrants to purchase Common Stock 283,514 6.81 1.93M 0
2018-12-31 Manning Paul B Director I Warrants to purchase Common Stock 553,752 6.81 3.77M 0

Executive team

Top executives
Shares Outstanding
54.90M

Executive compensation

Executive compensation (annual)
# Year Executive Salary Bonus Stock award Option award Incentive Other Total % Stock-
based
Filing
1 2025 Paul Peter Tak, M.D., Ph.D., FMedSci, Chief Executive Officer 743.6K 3.92M 396.7K 288.3K 5.34M 73.27%
2 2025 Francesca Barone, M.D., Ph.D. Chief Scientific Officer 483.3K 857.8K 206.4K 14.0K 1.56M 54.93%
3 2025 Charles Schoch Chief Financial Officer 398.5K 826.5K 232.3K 13.5K 1.47M 56.19%
4 2024 Paul Peter Tak, M.D., Ph.D., FMedSci, Chief Executive Officer 688.9K 498.1K 262.2K 1.45M 0.00%
5 2024 Paul Peter Tak, M.D., Ph.D, FMedSci, Chief Executive Officer 688.9K 498.1K 262.2K 1.45M 0.00%
6 2024 Francesca Barone, M.D., Ph.D. Chief Scientific Officer 443.3K 269.1K 13.8K 726.2K 0.00%
7 2024 Seshu Tyagarajan, Ph.D., RAC Chief Technical and Development Officer 401.4K 198.1K 13.8K 613.2K 0.00%
8 2023 Paul Peter Tak, M.D., Ph.D, FMedSci, Chief Executive Officer 670.0K 176.5K 189.6K 134.0K 314.7K 1.48M 24.65%
9 2023 Francesca Barone, M.D., Ph.D. Chief Scientific Officer 413.0K 110.5K 89.6K 80.6K 13.2K 706.9K 28.31%
10 2023 Jason A. Amello, Former Chief Financial Officer 466.0K 123.2K 89.6K 13.2K 692.0K 30.75%
11 2022 Paul Peter Tak, M.D., Ph.D, FMedSci, Chief Executive Officer 670.0K 335.0K 351.0K 259.6K 229.3K 1.84M 37.18%
12 2022 Seshu Tyagarajan, Ph.D., RAC Chief Technical and Development Officer 235.4K 20.0K 126.0K 454.8K 73.2K 6.6K 916.0K 63.40%
13 2022 Francesca Barone, M.D., Ph.D. Chief Scientific Officer 362.2K 155.4K 234.0K 144.5K 12.2K 908.3K 42.87%
14 2021 Paul Peter Tak, M.D., Ph.D., FMedSci, President and Chief Executive Officer 545.1K 85.0K 167.5K 159.2K 956.8K 0.00%
15 2021 Paul Peter Tak, M.D., Ph.D, FMedSci, Chief Executive Officer 545.1K 85.0K 167.5K 159.2K 956.8K 0.00%
16 2021 Estuardo Aguilar-Cordova, M.D., inf., Ph.D., Founder and Former Chief Executive Officer and Chief Scientific Officer 520.2K 6.2K 526.4K 0.00%
17 2021 John Canepa Chief Financial Officer 370.0K 74.0K 5.1K 449.1K 0.00%
18 2021 Francesca Barone, M.D., Ph.D. Chief Scientific Officer 259.7K 101.5K 3.6K 364.8K 0.00%
19 2020 Paul Peter Tak, M.D., Ph.D., FMedSci, President and Chief Executive Officer 134.6K 85.0K 2.32M 90.5K 2.63M 88.19%
20 2020 John Canepa Chief Financial Officer 14.2K 75.0K 1.23M 1.32M 93.24%
21 2020 Estuardo Aguilar-Cordova, M.D., inf., Ph.D., Founder and Former Chief Executive Officer and Chief Scientific Officer 444.9K 104.0K 191.3K 740.2K 0.00%
CEO compensation breakdown

Proxy statements

Proxy statements (DEF 14A)
Filing date Form type Filing
2026-04-29 DEFA14A
2026-04-29 DEF 14A
2025-04-29 DEFA14A
2025-04-29 DEF 14A

Recent SEC filings

Recent SEC filings
Filing date Form type Filing
2026-04-29 DEFA14A
2026-04-29 DEF 14A
2026-04-29 ARS
2026-04-27 SC 13G/A
2026-04-02 4
2026-04-02 4
2026-04-02 4
2026-03-18 SC 13D/A
2026-03-12 S-8
2026-03-12 8-K

Executive team

NameTitleCompensationGender
Paul-Peter Tak FOCIS President, Chief Executive Officer & Director 1M
Seshu Tyagarajan Chief Technical & Development Officer 613.2K
Francesca Barone Chief Scientific Officer 497.3K
Charles Schoch Senior VP, CFO, Treasurer & Secretary 412.0K male
Ileen Winick Chief People Officer female
Susan Stewart Chief Regulatory Officer female
William Nichols Garrett Chief Medical Officer
ESG Rating
B-
BIOTECHNOLOGY
Rank: 612 out of 638
2025
E (Environmental)
50.4 / 56.3
Company / Sector avg.
S (Social)
62.7 / 62.4
Company / Sector avg.
G (Governance)
57.8 / 60.9
Company / Sector avg.
ESG Total
57.0 / 59.9
Company / Sector avg.
ESG Score History BIOTECHNOLOGY
Benchmark vs Sector
Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
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Dividend history

Earnings history

Earnings reports

Stock splits