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Cabaletta Bio, Inc. (CABA)

USD2.71 +0.04 (+1.58%)
US NASDAQ Healthcare Biotechnology
Address 2929 Arch Street 19104
Philadelphia, PA, US
CEO Steven A. Nichtberger
IPO 2019-10-25
CIK 1759138 ISIN US12674W1099

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Description

Cabaletta Bio, Inc. is a biotechnology firm in the clinical development stage, specializing in the invention and advancement of sophisticated engineered T cell therapies. Its core mission is to treat autoimmune diseases where B cells are implicated in producing harmful autoantibodies. The company's unique chimeric autoantibody receptor (CAAR) T cell platform is engineered to precisely target and eradicate these specific disease-causing B cells. Leading its pipeline is DSG3-CAART, which is currently in Phase I clinical trials. This candidate is being assessed for efficacy in two distinct conditions: mucosal pemphigus vulgaris, an autoimmune blistering skin disorder, and Hemophilia A in patients exhibiting Factor VIII alloantibodies. Cabaletta's broader product candidate portfolio also includes MuSK-CAART, a preclinical asset aimed at a particular subset of myasthenia gravis patients; FVIII-CAART, in the discovery phase for another subgroup of Hemophilia A sufferers; and DSG3/1-CAART, also a discovery-stage program, designed for mucocutaneous pemphigus vulgaris. The company maintains strategic alliances, including a collaboration with the University of Pennsylvania and a research pact with The Regents of the University of California. Founded in 2017 as Tycho Therapeutics, Inc., it adopted the name Cabaletta Bio, Inc. in August 2018 and is based in Philadelphia, Pennsylvania.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
USD2.71 +0.04 (+1.58%)
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Volume Profile
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Liquidity & share structure
Average Volume
4M
Beta
3.23
Float Shares
84.30M
Free Float %
87.6%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
-8.31% -14.69% -3.78% +11.82% +38.49% +51.14% +72.40% -72.71% -64.56% -66.90% -66.90%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
vs.
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Analyst Consensus (12 ratings, all time) Buy
Price Targets & DCF
Current price
2.71
Low 3.00 +10.6%
Consensus 16.33 +502.1%
Median 14.00 +416.2%
High 32.00 +1,079.9%
DCF (Unlevered) 0.49 -81.9%
DCF (Levered) 0.55 -79.9%

DCF figures are point estimates: small changes in growth or discount-rate assumptions move them materially. Read them as a reference, not a precise target.

Ratings Trend (MoM) 80% Bullish
Rating 2026-05 Change
Strong Buy 1 0
Buy 7 0
Hold 2 0
Sell 0 0
Strong Sell 0 0
Price Target Summary
Period # Analysts Avg Target
Last Month
Last Quarter
Last Year
All Time 3
16.33
+502.1%
Quality scores
Altman Z-Score
-4.41
Distress
Piotroski F-Score
1 / 9
Weak
MOAT Score
3 / 10
No MOAT
Composite Rating
C
Overall Score
2 / 5
Medium
DCF Score
3 / 5
Medium
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
2 / 5
Medium
P/E Score
1 / 5
Low
P/Book Score
2 / 5
Medium
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
  • EPS growth Biotechnology: +29.7%
    +29.9% Q1'26: +46.6% (vs Q1'25)
  • FCF margin FCF growth · Biotechnology: +16.2%
  • EBIT margin Biotechnology: +0.0%
  • ROIC Biotechnology: -16.1%
    -3,103.4% Q1'26: -1,350.5% (vs Q1'25)
  • Share dilution Biotechnology: -3.4%
    +106.7% Q1'26: +126.4% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    -0.16× Q1'26: -0.15× (vs Q1'25)
Valuation Multiples From To
Price Forecast (3Y) From To
Model
Adjust
P/E
Theoretical Return — If Invested Today

* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.

DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (3.17) × ERP
WACC = 93% × Ke + 7% × Kd (7.4%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Intrinsic value (base): 0.49 Current price: 2.71
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2024
actual
Dec 2025
actual
Dec 2026
6 Rev. Ana.
6 EPS Ana.
Dec 2027
7 Rev. Ana.
4 EPS Ana.
Dec 2028
8 Rev. Ana.
7 EPS Ana.
Dec 2029
7 Rev. Ana.
2 EPS Ana.
Dec 2030
7 Rev. Ana.
5 EPS Ana.
Revenue
est: 4.38M (-100.0%)
2.50M
2.50M – 2.50M
-42.9% YoY
712.6K
712.6K – 712.6K
-71.5% YoY
63.68M
63.68M – 63.68M
+8,836.7% YoY
345.68M
345.68M – 345.68M
+442.8% YoY
787.60M
787.60M – 787.60M
+127.8% YoY
EBITDA
-110.30M
-170.60M
— – —
— – —
— – —
— – —
— – —
EBIT
-115.12M
-172.24M
— – —
— – —
— – —
— – —
— – —
Net Income
-115.86M
est: -116.44M (+0.5%)
-167.86M
est: -225.95M (+25.7%)
-135.16M
-167.14M – -103.17M
+40.2% YoY
-129.39M
-151.98M – -106.79M
+4.3% YoY
-240.24M
-254.01M – -49.23M
-85.7% YoY
-66.47M
-66.47M – -66.47M
+72.3% YoY
85.39M
85.39M – 85.39M
+228.5% YoY
SGA
23.13M
29.57M
— – —
— – —
— – —
— – —
— – —
EPS
-2.34
est: -2.34 (-0.1%)
-1.64
est: -2.19 (+25.1%)
-1.38
-1.63 – -1.01
+36.9% YoY
-1.27
-1.49 – -1.04
+8.5% YoY
-1.17
-2.48 – -0.48
+7.6% YoY
-0.65
-0.65 – -0.65
+44.4% YoY
0.84
0.84 – 0.84
+228.5% YoY
Recent Grade Changes (3M)
Date Firm Previous New Grade Action
2026-05-15 Wells Fargo Equal Weight Equal Weight Maintain
2026-05-04 Cantor Fitzgerald Overweight Overweight Maintain
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-15 C 2/5 3/5 1/5 1/5 2/5 1/5 2/5
2026-05-14 C 2/5 3/5 1/5 1/5 2/5 1/5 3/5
2026-05-13 C 2/5 3/5 1/5 1/5 2/5 1/5 3/5
2026-05-12 C 2/5 3/5 1/5 1/5 2/5 1/5 3/5
2026-05-11 C 2/5 3/5 1/5 1/5 2/5 1/5 3/5
2026-05-08 C 2/5 3/5 1/5 1/5 2/5 1/5 3/5
2026-05-07 C 2/5 3/5 1/5 1/5 2/5 1/5 3/5
2026-05-06 C 2/5 3/5 1/5 1/5 2/5 1/5 3/5
2026-05-05 C 2/5 3/5 1/5 1/5 2/5 1/5 3/5
2026-05-04 C 2/5 3/5 1/5 1/5 2/5 1/5 3/5
2026-05-01 C 2/5 3/5 1/5 1/5 2/5 1/5 3/5
2026-04-30 C 2/5 3/5 1/5 1/5 2/5 1/5 3/5
2026-04-29 C 2/5 3/5 1/5 1/5 2/5 1/5 3/5
2026-04-28 C 2/5 3/5 1/5 1/5 2/5 1/5 3/5
2026-04-27 C 2/5 3/5 1/5 1/5 2/5 1/5 3/5
2026-04-24 C 2/5 3/5 1/5 1/5 2/5 1/5 3/5
2026-04-23 C 2/5 3/5 1/5 1/5 1/5 1/5 3/5
2026-04-22 C 2/5 3/5 1/5 1/5 1/5 1/5 3/5
2026-04-21 C 2/5 3/5 1/5 1/5 1/5 1/5 3/5
2026-04-20 C 2/5 3/5 1/5 1/5 1/5 1/5 3/5
2026-04-17 C 2/5 3/5 1/5 1/5 1/5 1/5 3/5
2026-04-16 C 2/5 3/5 1/5 1/5 1/5 1/5 3/5

Owner Earnings

Owner's Earnings (history)

Owner's Earnings history not available.

Owner alignment
Owner's Earnings TTM
OE per share TTM
Owner's Yield
Maintenance CapEx ratio
Maint CapEx / Avg PPE

Ownership Overview

Ownership breakdown
At a glance
Institutional holders
61
Total invested
65.51M
Insider transactions (90d)
0
Beneficial owners (>5%)
29
Beneficial owners (>5%)
# Reporting person Amount owned % of class Sole voting Shared voting Sole dispositive Shared dispositive Type Citizenship Filing date SEC filing
1 (1) BlackRock, Inc. 4.41M 10.30% 4.38M 4.41M HC Delaware 2024-01-08
2 85-4328500 3.67M 7.50% 3.67M 3.67M IA Maryland 2024-11-14
3 13-3017981 3.48M 11.90% 3.48M 3.48M HC New York 2023-02-10
4 Bain Capital Life Sciences Opportunities III, LP 2.76M 5.70% 2.76M 2.76M PN Delaware 2024-08-22
5 STATE STREET CORPORATION 2.59M 6.05% 2.52M 2.59M HC BOSTON, MASSACHUSETTS 2024-01-24
6 Company, L.P. 2.34M 5.90% 2.34M PN Delaware 2023-05-26
7 James E. Flynn 2.34M 5.90% 2.34M IN Delaware 2023-05-26
8 Bihua Chen 2.00M 7.81% 2.00M IN United States 2022-10-31
9 Koh, Bong 1.90M 6.50% 1.90M IN United States 2022-12-23
10 Shah, Nimish 1.90M 6.50% 1.90M IN United States 2022-12-23
11 VHCP Co-Investment Holdings III, LLC 1.90M 6.50% 1.90M OO United States 2022-12-23
12 VHCP Management EG, LLC 1.90M 6.50% 1.90M OO United States 2022-12-23
13 VHCP Management III, LLC 1.90M 6.50% 1.90M OO United States 2022-12-23
14 Venrock Healthcare Capital Partners EG, L.P. 1.90M 6.50% 1.90M PN United States 2022-12-23
15 Venrock Healthcare Capital Partners III, L.P. 1.90M 6.50% 1.90M PN United States 2022-12-23
16 Deerfield Mgmt, L.P. 1.88M 4.73% 1.88M PN Delaware 2023-05-26
17 Deerfield Partners, L.P. 1.88M 4.73% 1.88M PN Delaware 2023-05-26
18 Steven Nichtberger 1.86M 6.40% 1.86M 1.86M IN United States of America 2022-11-07
19 Capital LP 1.46M 5.00% 1.46M 1.46M IA Delaware, USA 2023-01-13
20 Capital Master LP 1.46M 5.00% 1.46M 1.46M OO Delaware, USA 2023-01-13
21 Baker Bros. Advisors (GP) LLC 1.34M 5.20% 1.34M 1.34M HC, OO Delaware 2023-02-14
22 Baker Bros. Advisors LP 1.34M 5.20% 1.34M 1.34M IA, PN 2023-02-14
23 Felix J. Baker 1.34M 5.20% 1.34M 1.34M HC, IN 2023-02-14
24 Julian C. Baker 1.34M 5.20% 1.34M 1.34M HC, IN 2023-02-14
25 Cormorant Private Healthcare Fund II, LP 1.15M 4.51% 1.15M PN Delaware 2022-10-31
26 Cormorant Private Healthcare GP II, LLC 1.15M 4.51% 1.15M OO Delaware 2022-10-31
27 Cormorant Global Healthcare GP, LLC 845.6K 3.30% 845.6K OO Delaware 2022-10-31
28 Deerfield Mgmt IV, L.P. 464.3K 1.17% 464.3K PN Delaware 2023-05-26
29 Deerfield Private Design Fund IV, L.P. 464.3K 1.17% 464.3K PN Delaware 2023-05-26

Institutional Activity (13F)

Institutional ownership trend From To
13F snapshot — 2026 Q1
Investors holding
61
-37 vs prev Q
New positions
17
Closed positions
52
Increased
33
Reduced
11
Put/Call ratio
0.16
Calls held
172.8K
Puts held
27.3K
Top institutional holders
# Investor Shares / Δ Mkt value / Δ Own% / Δ Weight% / Δ Avg px / Perf. Hold / Status
1 505.4K +505.4K (+100.0%) 1.11B +1.1B (+100.0%) 0.49% +0.494 pp 1.07% +1.071 pp USD2.19 +0.0% 1 qtrs NEW
2 T. ROWE PRICE INVESTMENT MANAGEMENT, INC. 9.86M +1.5M (+17.9%) 21.59M +2.0M (+10.3%) 9.64% +1.463 pp 0.01% +0.002 pp USD7.16 -69.4% 9 qtrs
3 BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC 9.68M +— (+0.0%) 21.19M -1.5M (-6.4%) 9.46% +0.000 pp 1.62% +0.120 pp USD3.81 -42.5% 11 qtrs
4 JENNISON ASSOCIATES LLC 8.91M +408.2K (+4.8%) 19.50M -380.8K (-1.9%) 8.71% +0.399 pp 0.01% +0.000 pp USD4.62 -52.6% 12 qtrs
5 ADAGE CAPITAL PARTNERS GP, L.L.C. 8.83M +— (+0.0%) 19.34M -1.3M (-6.4%) 8.63% +0.000 pp 0.03% -0.004 pp USD5.77 -62.0% 25 qtrs
6 VANGUARD GROUP INC 4.42M +228.7K (+5.5%) 9.68M -127.8K (-1.3%) 4.32% +0.224 pp 0.00% +0.000 pp USD7.17 -69.5% 25 qtrs
7 CORMORANT ASSET MANAGEMENT, LP 4.40M -600.0K (-12.0%) 9.64M -2.1M (-17.6%) 4.30% -0.587 pp 0.45% -0.362 pp USD1.52 +44.1% 3 qtrs
8 MILLENNIUM MANAGEMENT LLC 2.74M +2.1M (+298.5%) 5.99M +4.4M (+273.0%) 2.68% +2.005 pp 0.00% +0.002 pp USD2.37 -7.6% 8 qtrs
9 BLACKROCK, INC. 2.33M +707.6K (+43.7%) 5.10M +1.3M (+34.4%) 2.28% +0.692 pp 0.00% +0.000 pp USD3.26 -32.8% 6 qtrs
10 SUPERSTRING CAPITAL MANAGEMENT LP 2.25M +709.0K (+45.9%) 4.94M +1.3M (+36.6%) 2.20% +0.693 pp 2.64% -0.918 pp USD2.53 -13.4% 8 qtrs
11 TWO SIGMA INVESTMENTS, LP 1.84M +1.4M (+291.1%) 4.03M +2.9M (+266.0%) 1.80% +1.339 pp 0.01% +0.004 pp USD2.67 -18.0% 23 qtrs
12 RENAISSANCE TECHNOLOGIES LLC 1.52M +183.2K (+13.7%) 3.33M +200.2K (+6.4%) 1.49% +0.179 pp 0.01% +0.001 pp USD2.26 -3.1% 5 qtrs
13 MORGAN STANLEY 1.34M -131.0K (-8.9%) 2.94M -508.0K (-14.7%) 1.31% -0.128 pp 0.00% +0.000 pp USD4.83 -54.7% 25 qtrs
14 WOODLINE PARTNERS LP 1.25M -885.1K (-41.5%) 2.74M -2.3M (-45.2%) 1.22% -0.866 pp 0.01% -0.013 pp USD1.87 +17.1% 3 qtrs
15 SCHONFELD STRATEGIC ADVISORS LLC 1.20M +159.9K (+15.3%) 2.64M +193.6K (+7.9%) 1.18% +0.156 pp 0.01% -0.002 pp USD1.50 +46.0% 4 qtrs
16 PRICE T ROWE ASSOCIATES INC /MD/ 1.09M -201.0K (-15.5%) 2.40M -634.0K (-20.9%) 1.07% -0.197 pp 0.00% 0.000 pp USD6.02 -63.6% 11 qtrs
17 GEODE CAPITAL MANAGEMENT, LLC 1.09M +165.5K (+18.0%) 2.38M +224.9K (+10.4%) 1.06% +0.162 pp 0.00% +0.000 pp USD6.81 -67.8% 25 qtrs
18 MARSHALL WACE, LLP 959.1K -367.0K (-27.7%) 2.10M -1.0M (-32.3%) 0.94% -0.359 pp 0.00% -0.001 pp USD2.50 -12.4% 8 qtrs
19 IKARIAN CAPITAL, LLC 900.0K +900.0K (+100.0%) 1.97M +2.0M (+100.0%) 0.88% +0.880 pp 0.15% +0.154 pp USD2.19 +0.0% 1 qtrs NEW
20 OPALEYE MANAGEMENT INC. 900.0K +91.1K (+11.3%) 1.97M +78.2K (+4.1%) 0.88% +0.089 pp 0.26% -0.008 pp USD2.32 -5.6% 2 qtrs
21 SCHRODER INVESTMENT MANAGEMENT GROUP 756.6K +756.6K (+100.0%) 1.63M +1.6M (+100.0%) 0.74% +0.740 pp 0.00% +0.001 pp USD2.19 +0.0% 1 qtrs NEW
22 TWO SIGMA ADVISERS, LP 737.9K +406.9K (+122.9%) 1.62M +841.5K (+108.6%) 0.72% +0.398 pp 0.00% +0.002 pp USD2.72 -19.5% 7 qtrs
23 BURKEHILL GLOBAL MANAGEMENT, LP 700.0K +— (+0.0%) 1.53M -105.0K (-6.4%) 0.68% +0.000 pp 0.10% +0.008 pp USD1.52 +44.1% 3 qtrs
24 ENSIGN PEAK ADVISORS, INC 550.0K +550.0K (+100.0%) 1.20M +1.2M (+100.0%) 0.54% +0.538 pp 0.00% +0.002 pp USD2.19 +0.0% 1 qtrs NEW
25 DIMENSIONAL FUND ADVISORS LP 452.0K +452.0K (+100.0%) 990.0K +990.0K (+100.0%) 0.44% +0.442 pp 0.00% +0.000 pp USD2.19 +0.0% 1 qtrs NEW
26 RAIFFEISEN BANK INTERNATIONAL AG 450.0K +100.0K (+28.6%) 967.5K +134.5K (+16.1%) 0.44% +0.098 pp 0.01% +0.001 pp USD2.10 +4.3% 5 qtrs
27 GOLDMAN SACHS GROUP INC 430.7K +158.1K (+58.0%) 943.2K +305.3K (+47.9%) 0.42% +0.155 pp 0.00% +0.000 pp USD7.29 -70.0% 24 qtrs
28 STATE STREET CORP 425.5K +48.7K (+12.9%) 931.8K +50.1K (+5.7%) 0.42% +0.048 pp 0.00% +0.000 pp USD9.72 -77.5% 25 qtrs
29 UBS GROUP AG 415.7K +10.6K (+2.6%) 910.3K -37.6K (-4.0%) 0.41% +0.010 pp 0.00% +0.000 pp USD2.94 -25.5% 14 qtrs
30 683 CAPITAL MANAGEMENT, LLC 388.6K +388.6K (+100.0%) 851.0K +851.0K (+100.0%) 0.38% +0.380 pp 0.04% +0.037 pp USD2.19 +0.0% 1 qtrs NEW
31 ALMITAS CAPITAL LLC 387.5K +— (+0.0%) 848.6K -58.1K (-6.4%) 0.38% +0.000 pp 0.19% -0.021 pp USD1.44 +52.1% 4 qtrs
32 QUBE RESEARCH & TECHNOLOGIES LTD 331.2K +242.1K (+271.5%) 725.4K +516.8K (+247.7%) 0.32% +0.237 pp 0.00% +0.001 pp USD2.23 -1.8% 2 qtrs
33 GSA CAPITAL PARTNERS LLP 304.0K +304.0K (+100.0%) 666.0K +666.0K (+100.0%) 0.30% +0.297 pp 0.06% +0.057 pp USD2.19 +0.0% 1 qtrs NEW
34 BOOTHBAY FUND MANAGEMENT, LLC 243.4K +243.4K (+100.0%) 533.1K +533.1K (+100.0%) 0.24% +0.238 pp 0.01% +0.008 pp USD2.19 +0.0% 1 qtrs NEW
35 NORTHERN TRUST CORP 238.4K +11.5K (+5.0%) 522.2K -9.0K (-1.7%) 0.23% +0.011 pp 0.00% +0.000 pp USD7.26 -69.8% 25 qtrs
36 CITADEL ADVISORS LLC 222.6K -22.2K (-9.1%) 487.5K -85.3K (-14.9%) 0.22% -0.022 pp 0.00% +0.000 pp USD2.49 -12.0% 14 qtrs
37 BARCLAYS PLC 220.7K +159.6K (+261.0%) 483.3K +194.8K (+67.5%) 0.22% +0.117 pp 0.00% +0.000 pp USD2.68 -18.3% 16 qtrs
38 INVESCO LTD. 189.2K +66.4K (+54.1%) 414.3K +127.0K (+44.2%) 0.19% +0.065 pp 0.00% +0.000 pp USD2.97 -26.3% 11 qtrs
39 JANE STREET GROUP, LLC 179.1K -11.1K (-5.8%) 392.2K -52.8K (-11.9%) 0.18% -0.011 pp 0.00% +0.000 pp USD2.00 +9.5% 5 qtrs
40 STONEPINE CAPITAL MANAGEMENT, LLC 171.1K +171.1K (+100.0%) 374.7K +374.7K (+100.0%) 0.17% +0.167 pp 0.27% +0.274 pp USD2.19 +0.0% 1 qtrs NEW
41 XTX TOPCO LTD 155.4K -128.9K (-45.3%) 340.3K -325.0K (-48.8%) 0.15% -0.126 pp 0.01% -0.026 pp USD2.06 +6.3% 3 qtrs
42 GRAHAM CAPITAL MANAGEMENT, L.P. 151.5K +151.5K (+100.0%) 331.7K +331.7K (+100.0%) 0.15% +0.148 pp 0.01% +0.008 pp USD2.19 +0.0% 1 qtrs NEW
43 SQUAREPOINT OPS LLC 149.1K +137.2K (+1,156.3%) 326.5K +298.7K (+1,075.7%) 0.15% +0.134 pp 0.00% +0.000 pp USD2.14 +2.3% 12 qtrs
44 HUDSON BAY CAPITAL MANAGEMENT LP 138.7K +138.7K (+100.0%) 303.8K +303.8K (+100.0%) 0.14% +0.136 pp 0.00% +0.001 pp USD2.19 +0.0% 3 qtrs
45 SUSQUEHANNA INTERNATIONAL GROUP, LLP 138.3K -233.8K (-62.8%) 302.8K -567.9K (-65.2%) 0.14% -0.229 pp 0.00% 0.000 pp USD2.32 -5.6% 9 qtrs
46 BRIDGEWAY CAPITAL MANAGEMENT, LLC 130.7K +35.0K (+36.6%) 286.2K +62.3K (+27.8%) 0.13% +0.034 pp 0.01% +0.001 pp USD2.28 -3.9% 5 qtrs
47 OMERS ADMINISTRATION CORP 95.4K +95.4K (+100.0%) 208.9K +208.9K (+100.0%) 0.09% +0.093 pp 0.00% +0.002 pp USD2.19 +0.0% 1 qtrs NEW
48 LETKO, BROSSEAU & ASSOCIATES INC 90.5K +90.5K (+100.0%) 198.1K +198.1K (+100.0%) 0.09% +0.089 pp 0.00% +0.003 pp USD2.19 +0.0% 1 qtrs NEW
49 TD ASSET MANAGEMENT INC 88.6K +— (+0.0%) 194.0K -13.3K (-6.4%) 0.09% +0.000 pp 0.00% +0.000 pp USD20.46 -89.3% 9 qtrs
50 CITIGROUP INC 73.8K +73.4K (+20,858.5%) 161.6K +160.7K (+19,507.4%) 0.07% +0.072 pp 0.00% +0.000 pp USD2.21 -0.9% 12 qtrs
51 DYNAMIC TECHNOLOGY LAB PRIVATE LTD 66.8K +66.8K (+100.0%) 146.0K +146.0K (+100.0%) 0.07% +0.065 pp 0.03% +0.033 pp USD2.19 +0.0% 1 qtrs NEW
52 QUADRATURE CAPITAL LTD 66.4K +23.5K (+54.7%) 145.4K +45.0K (+44.8%) 0.06% +0.023 pp 0.00% +0.000 pp USD2.29 -4.4% 2 qtrs
53 AMERICAN CENTURY COMPANIES INC 58.8K +46.7K (+388.5%) 128.7K +100.6K (+357.2%) 0.06% +0.046 pp 0.00% +0.000 pp USD2.22 -1.4% 2 qtrs
54 POINT72 ASSET MANAGEMENT, L.P. 56.6K +56.6K (+100.0%) 124.1K +124.1K (+100.0%) 0.06% +0.055 pp 0.00% +0.000 pp USD2.19 +0.0% 1 qtrs NEW
55 MATAURO, LLC 55.1K +55.1K (+100.0%) 120.7K +120.7K (+100.0%) 0.05% +0.054 pp 0.02% +0.018 pp USD2.19 +0.0% 1 qtrs NEW
56 BANK OF NEW YORK MELLON CORP 54.0K +6.2K (+13.0%) 118.4K +6.5K (+5.8%) 0.05% +0.006 pp 0.00% +0.000 pp USD9.83 -77.7% 25 qtrs
57 BALYASNY ASSET MANAGEMENT L.P. 51.6K +51.6K (+100.0%) 112.9K +112.9K (+100.0%) 0.05% +0.050 pp 0.00% +0.000 pp USD2.19 +0.0% 1 qtrs NEW
58 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 50.8K +— (+0.0%) 111.3K -7.6K (-6.4%) 0.05% +0.000 pp 0.00% +0.000 pp USD8.37 -73.8% 13 qtrs
59 JEFFERIES FINANCIAL GROUP INC. 45.1K -2.4K (-5.0%) 98.8K -12.3K (-11.1%) 0.04% -0.002 pp 0.00% +0.000 pp USD1.52 +44.1% 3 qtrs
60 LPL FINANCIAL LLC 42.6K +42.6K (+100.0%) 93.3K +93.3K (+100.0%) 0.04% +0.042 pp 0.00% +0.000 pp USD2.19 +0.0% 1 qtrs NEW
61 LIGHTHOUSE INVESTMENT PARTNERS, LLC 38.9K +38.9K (+100.0%) 85.1K +85.1K (+100.0%) 0.04% +0.038 pp 0.00% +0.003 pp USD2.19 +0.0% 1 qtrs NEW
62 SG AMERICAS SECURITIES, LLC 30.6K +9.4K (+44.0%) 67.0K +17.0K (+34.0%) 0.03% +0.009 pp 0.00% 0.000 pp USD3.63 -39.7% 6 qtrs
63 TOWER RESEARCH CAPITAL LLC (TRC) 30.3K +26.0K (+594.9%) 66.5K +56.2K (+550.3%) 0.03% +0.025 pp 0.00% +0.001 pp USD2.20 -0.5% 25 qtrs
64 FRED ALGER MANAGEMENT, LLC 28.0K -31.8K (-53.2%) 61.4K -78.6K (-56.2%) 0.03% -0.031 pp 0.00% 0.000 pp USD7.34 -70.2% 13 qtrs
65 MERCER GLOBAL ADVISORS INC /ADV 26.5K +26.5K (+100.0%) 58.1K +58.1K (+100.0%) 0.03% +0.026 pp 0.00% +0.000 pp USD2.19 +0.0% 1 qtrs NEW
66 CALLAN FAMILY OFFICE, LLC 22.6K +22.6K (+100.0%) 49.4K +49.4K (+100.0%) 0.02% +0.022 pp 0.00% +0.001 pp USD2.19 +0.0% 1 qtrs NEW
67 VANGUARD PERSONALIZED INDEXING MANAGEMENT, LLC 22.4K +233.0 (+1.1%) 49.0K -2.8K (-5.4%) 0.02% +0.000 pp 0.00% 0.000 pp USD3.06 -28.4% 6 qtrs
68 JONES FINANCIAL COMPANIES LLLP 20.7K +653.0 (+3.3%) 45.2K -2.0K (-4.2%) 0.02% +0.001 pp 0.00% +0.000 pp USD2.34 -6.4% 5 qtrs
69 CLEAR HARBOR ASSET MANAGEMENT, LLC 19.5K +19.5K (+100.0%) 42.7K +42.7K (+100.0%) 0.02% +0.019 pp 0.00% +0.003 pp USD2.19 +0.0% 1 qtrs NEW
70 ANTIPODES PARTNERS LTD 17.2K +17.2K (+100.0%) 37.6K +37.6K (+100.0%) 0.02% +0.017 pp 0.00% +0.001 pp USD2.19 +0.0% 1 qtrs NEW
71 CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD. 15.7K +15.7K (+100.0%) 34.4K +34.4K (+100.0%) 0.02% +0.015 pp 0.00% +0.003 pp USD2.19 +0.0% 1 qtrs NEW
72 CRA FINANCIAL SERVICES, LLC 15.0K +— (+0.0%) 32.9K -2.3K (-6.4%) 0.01% +0.000 pp 0.00% -0.001 pp USD1.64 +33.5% 4 qtrs
73 PRIVATE ADVISOR GROUP, LLC 14.7K +14.7K (+100.0%) 32.2K +32.2K (+100.0%) 0.01% +0.014 pp 0.00% +0.000 pp USD2.19 +0.0% 1 qtrs NEW
74 BANK OF AMERICA CORP /DE/ 14.4K -253.7K (-94.6%) 31.5K -595.7K (-95.0%) 0.01% -0.419 pp 0.00% +0.000 pp USD4.99 -56.1% 25 qtrs
75 FMR LLC 13.0K -1.0K (-7.2%) 28.6K -4.3K (-13.2%) 0.01% -0.001 pp 0.00% +0.000 pp USD1.81 +21.0% 12 qtrs
76 MANUFACTURERS LIFE INSURANCE COMPANY, THE 13.0K -73.0 (-0.6%) 28.0K -2.6K (-8.4%) 0.01% 0.000 pp 0.00% +0.000 pp USD19.06 -88.5% 11 qtrs
77 HB WEALTH MANAGEMENT, LLC 10.0K +10.0K (+100.0%) 21.9K +21.9K (+100.0%) 0.01% +0.010 pp 0.00% +0.000 pp USD2.19 +0.0% 1 qtrs NEW
78 JPMORGAN CHASE & CO 9.8K -527.8K (-98.2%) 21.5K -1.2M (-98.3%) 0.01% -0.859 pp 0.00% 0.000 pp USD3.20 -31.6% 25 qtrs
79 MIRAE ASSET GLOBAL INVESTMENTS CO., LTD. 4.7K +4.7K (+100.0%) 10.2K +10.2K (+100.0%) 0.00% +0.005 pp 0.00% +0.000 pp USD2.19 +0.0% 1 qtrs NEW
80 PNC FINANCIAL SERVICES GROUP, INC. 4.6K +4.0K (+666.7%) 10.1K +8.7K (+617.5%) 0.00% +0.004 pp 0.00% +0.000 pp USD2.11 +3.8% 12 qtrs
81 CANADA PENSION PLAN INVESTMENT BOARD 3.5K +3.5K (+100.0%) 7.7K +7.7K (+100.0%) 0.00% +0.003 pp 0.00% +0.000 pp USD2.19 +0.0% 1 qtrs NEW
82 WELLS FARGO & COMPANY/MN 2.0K -1.0K (-33.3%) 4.4K -2.6K (-37.6%) 0.00% -0.001 pp 0.00% +0.000 pp USD7.26 -69.8% 25 qtrs
83 GF FUND MANAGEMENT CO. LTD. 1.9K +1.9K (+100.0%) 4.1K +4.1K (+100.0%) 0.00% +0.002 pp 0.00% +0.000 pp USD2.19 +0.0% 1 qtrs NEW
84 BNP PARIBAS ARBITRAGE, SNC 1.6K -191.0 (-10.4%) 3.6K -693.0 (-16.2%) 0.00% 0.000 pp 0.00% +0.000 pp USD2.13 +2.8% 5 qtrs
85 FLAGSHIP HARBOR ADVISORS, LLC 1.0K +1.0K (+100.0%) 2.2K +2.2K (+100.0%) 0.00% +0.001 pp 0.00% +0.000 pp USD2.19 +0.0% 1 qtrs NEW
86 RUSSELL INVESTMENTS GROUP, LTD. 939.00 +— (+0.0%) 2.1K -141.0 (-6.4%) 0.00% +0.000 pp 0.00% +0.000 pp USD1.52 +44.1% 10 qtrs
87 NISA INVESTMENT ADVISORS, LLC 811.00 +— (+0.0%) 1.8K -122.0 (-6.4%) 0.00% +0.000 pp 0.00% +0.000 pp USD2.74 -20.1% 10 qtrs
88 TRUVESTMENTS CAPITAL LLC 680.00 +— (+0.0%) 1.5K -102.0 (-6.4%) 0.00% +0.000 pp 0.00% +0.000 pp USD3.07 -28.7% 6 qtrs
89 FEDERATION DES CAISSES DESJARDINS DU QUEBEC 340.00 +— (+0.0%) 745.00 -51.0 (-6.4%) 0.00% +0.000 pp 0.00% +0.000 pp USD11.10 -80.3% 20 qtrs
90 SBI SECURITIES CO., LTD. 316.00 -140.0 (-30.7%) 692.00 -375.0 (-35.1%) 0.00% 0.000 pp 0.00% +0.000 pp USD1.46 +50.0% 5 qtrs
91 NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO 60.00 +58.0 (+2,900.0%) 131.00 +126.0 (+2,520.0%) 0.00% +0.000 pp 0.00% +0.000 pp USD2.18 +0.5% 2 qtrs
92 OPTIVER HOLDING B.V. 24.00 +— (+0.0%) 53.00 -3.0 (-5.4%) 0.00% +0.000 pp 0.00% +0.000 pp USD2.33 -6.0% 2 qtrs
93 SRS CAPITAL ADVISORS, INC. 10.00 +— (+0.0%) 22.00 -1.0 (-4.3%) 0.00% +0.000 pp 0.00% +0.000 pp USD2.30 -4.8% 2 qtrs
94 HEIGHTS CAPITAL MANAGEMENT, INC -2.1M (-100.0%) -4.9M (-100.0%) 0.00% -2.038 pp 0.00% -1.337 pp USD 3 qtrs SOLD
95 FEDERATED HERMES, INC. -112.0K (-100.0%) -262.1K (-100.0%) 0.00% -0.110 pp 0.00% -0.001 pp USD 6 qtrs SOLD
Ownership breakdown by holder

ETF Ownership

Top ETFs holding this stock Held by 62 ETFs in our universe
# ETF Weight Est. AUM exposure TER
1 Virtus Biotech Clinical Trials ETF BBC 0.61% 350.2K 0.65%
2 Global X - S&P Biotech ETF CURE.AX 0.15% 52.2K 0.45%
3 State Street SPDR S&P Biotech ETF XBI 0.14% 15.68M 0.35%
4 iShares Micro-Cap ETF IWC 0.07% 1.11M 0.60%
5 Invesco NASDAQ Biotech UCITS ETF SBIO.L 0.03% 154.4K 0.40%
6 Invesco Nasdaq Biotechnology ETF IBBQ 0.03% 24.9K 0.19%
7 iShares Nasdaq US Biotechnology UCITS ETF BTEC.L 0.03% 365.5K 0.35%
8 iShares Nasdaq US Biotechnology UCITS ETF BTEE.L 0.03% 24.5K 0.35%
9 iShares Biotechnology ETF IBB 0.03% 3.05M 0.44%
10 Pacer WealthShield ETF PWS 0.03% 7.3K 0.60%

Insider Activity

Insider Activity — Latest Quarter
Ratio by transactions
0.00
Bearish
Buys
14
Sells
0
Shares acquired
1.83M
Shares disposed
Cash buys
8.00
Cash sales
Net activity
+1,831,073
Insider buys vs sells (history) From To
Recent insider transactions From To
Date Person Role Transaction A/D Security Shares Price Value Owned after D/I Filing
2026-03-02 Nichtberger Steven Director / Officer A-Award A Stock Option (Right to Buy) 674,000 3.30 2.22M 674,000 D
2026-03-02 Marda Anup Officer A-Award A Stock Option (Right to Buy) 225,000 3.30 742.5K 225,000 D
2026-03-02 Gerard Michael Officer A-Award A Stock Option (Right to Buy) 175,000 3.30 577.5K 175,000 D
2026-03-02 Das Arun Officer A-Award A Stock Option (Right to Buy) 175,000 3.30 577.5K 175,000 D
2026-03-02 Chang David J. Officer A-Award A Stock Option (Right to Buy) 225,000 3.30 742.5K 225,000 D
2026-03-02 Binder Gwendolyn Officer A-Award A Stock Option (Right to Buy) 225,000 3.30 742.5K 225,000 D
2026-01-21 Tomasello Shawn Director P-Purchase A Common Stock 22,725 2.21 50.3K 22,725 I
2026-01-21 Simon Mark Director P-Purchase A Common Stock 11,061 2.28 25.3K 147,205 D
2026-01-21 Nichtberger Steven Director / Officer P-Purchase A Common Stock 45,000 2.24 100.8K 1,031,483 D
2026-01-21 Gerard Michael Officer P-Purchase A Common Stock 6,600 2.27 15.0K 6,600 D
2026-01-21 Gavel Steve Officer P-Purchase A Common Stock 22,170 2.27 50.2K 22,170 D
2026-01-21 Chang David J. Officer P-Purchase A Common Stock 8,800 2.26 19.9K 8,800 D
2026-01-21 Bollard Catherine Director P-Purchase A Common Stock 4,405 2.27 10.0K 5,405 D
2026-01-21 Binder Gwendolyn Officer P-Purchase A Common Stock 11,312 2.19 24.8K 31,312 D
2025-10-13 Gavel Steve Officer A-Award A Stock Option (Right to Buy) 275,000 2.49 684.8K 275,000 D
2025-06-09 Tomasello Shawn Director A-Award A Stock Option (Right to Buy) 22,000 2.37 52.1K 22,000 D
2025-06-09 Simon Mark Director A-Award A Stock Option (Right to Buy) 22,000 2.37 52.1K 22,000 D
2025-06-09 HENRIQUES RICHARD C JR Director A-Award A Stock Option (Right to Buy) 22,000 2.37 52.1K 22,000 D
2025-06-09 Brun Scott C. Director A-Award A Stock Option (Right to Buy) 22,000 2.37 52.1K 22,000 D
2025-06-09 Bollard Catherine Director A-Award A Stock Option (Right to Buy) 22,000 2.37 52.1K 22,000 D
2025-05-19 Tomasello Shawn Director D-Return D Stock Option (Right to Buy) 22,000 10.01 220.2K 0 D
2025-05-19 Simon Mark Director A-Award A Stock Option (Right to Buy) 18,460 1.92 35.4K 18,460 D
2025-05-19 Nichtberger Steven Director / Officer A-Award A Stock Option (Right to Buy) 99,714 1.92 191.5K 99,714 D
2025-05-19 Marda Anup Officer D-Return D Stock Option (Right to Buy) 100,000 11.47 1.15M 0 D
2025-05-19 HENRIQUES RICHARD C JR Director A-Award A Stock Option (Right to Buy) 46,428 1.92 89.1K 46,428 D
2025-05-19 Gerard Michael Officer D-Return D Stock Option (Right to Buy) 100,000 10.93 1.09M 0 D
2025-05-19 Das Arun Officer A-Award A Stock Option (Right to Buy) 18,416 1.92 35.4K 18,416 D
2025-05-19 Chang David J. Officer A-Award A Stock Option (Right to Buy) 150,000 1.92 288.0K 150,000 D
2025-05-19 Brun Scott C. Director D-Return D Stock Option (Right to Buy) 22,000 10.01 220.2K 0 D
2025-05-19 Bollard Catherine Director D-Return D Stock Option (Right to Buy) 46,428 6.30 292.5K 0 D
2025-05-19 Binder Gwendolyn Officer A-Award A Stock Option (Right to Buy) 29,908 1.92 57.4K 29,908 D
2025-03-03 Nichtberger Steven Director / Officer A-Award A Stock Option (Right to Buy) 450,000 1.67 751.5K 450,000 D
2025-03-03 Marda Anup Officer A-Award A Stock Option (Right to Buy) 145,000 1.67 242.2K 145,000 D
2025-03-03 Gerard Michael Officer A-Award A Stock Option (Right to Buy) 115,000 1.67 192.1K 115,000 D
2025-03-03 Das Arun Officer A-Award A Stock Option (Right to Buy) 115,000 1.67 192.1K 115,000 D
2025-03-03 Chang David J. Officer A-Award A Stock Option (Right to Buy) 145,000 1.67 242.2K 145,000 D
2025-03-03 Binder Gwendolyn Officer A-Award A Stock Option (Right to Buy) 145,000 1.67 242.2K 145,000 D
2024-06-03 Tomasello Shawn Director A-Award A Stock Option (Right to Buy) 22,000 10.01 220.2K 22,000
2024-06-03 Simon Mark Director A-Award A Stock Option (Right to Buy) 22,000 10.01 220.2K 22,000
2024-06-03 HENRIQUES RICHARD C JR Director A-Award A Stock Option (Right to Buy) 22,000 10.01 220.2K 22,000
2024-06-03 Brun Scott C. Director A-Award A Stock Option (Right to Buy) 22,000 10.01 220.2K 22,000
2024-06-03 Bollard Catherine Director A-Award A Stock Option (Right to Buy) 22,000 10.01 220.2K 22,000
2024-03-01 Nichtberger Steven Director / Officer A-Award A Stock Option (Right to Buy) 353,000 23.97 8.46M 353,000
2024-03-01 Marda Anup Officer A-Award A Stock Option (Right to Buy) 130,000 23.97 3.12M 130,000
2024-03-01 Gerard Michael Officer A-Award A Stock Option (Right to Buy) 100,000 23.97 2.40M 100,000
2024-03-01 Das Arun Officer A-Award A Stock Option (Right to Buy) 100,000 23.97 2.40M 100,000
2024-03-01 Chang David J. Officer A-Award A Stock Option (Right to Buy) 130,000 23.97 3.12M 130,000
2024-03-01 Binder Gwendolyn Officer A-Award A Stock Option (Right to Buy) 130,000 23.97 3.12M 130,000
2024-01-19 Binder Gwendolyn Officer M-Exempt D Stock Option (Right to Buy) 11,000 1.01 11.1K 100,756
2023-12-19 Binder Gwendolyn Officer M-Exempt D Stock Option (Right to Buy) 11,000 1.01 11.1K 111,756
2023-11-20 Binder Gwendolyn Officer M-Exempt D Stock Option (Right to Buy) 11,000 1.01 11.1K 122,756
2023-10-19 Binder Gwendolyn Officer S-Sale D Common Stock 408 14.28 5.8K 20,000
2023-09-19 Binder Gwendolyn Officer S-Sale D Common Stock 10,300 17.50 180.3K 20,700
2023-08-21 Binder Gwendolyn Officer M-Exempt D Stock Option (Right to Buy) 11,000 1.01 11.1K 155,756
2023-07-21 Tomasello Shawn Director A-Award A Stock Option (Right to Buy) 44,000 13.48 593.1K 44,000
2023-07-19 Binder Gwendolyn Officer M-Exempt D Stock Option (Right to Buy) 11,000 1.01 11.1K 166,756
2023-06-20 Binder Gwendolyn Officer S-Sale D Common Stock 11,000 12.99 142.9K 20,000
2023-06-01 Simon Mark Director A-Award A Stock Option (Right to Buy) 22,000 11.18 246.0K 22,000
2023-06-01 HENRIQUES RICHARD C JR Director A-Award A Stock Option (Right to Buy) 22,000 11.18 246.0K 22,000
2023-06-01 Brun Scott C. Director A-Award A Stock Option (Right to Buy) 22,000 11.18 246.0K 22,000
2023-06-01 Bollard Catherine Director A-Award A Stock Option (Right to Buy) 22,000 11.18 246.0K 22,000
2023-05-19 Binder Gwendolyn Officer M-Exempt D Stock Option (Right to Buy) 22,000 1.01 22.2K 188,756
2023-01-18 Nichtberger Steven Officer A-Award A Stock Option (Right to Buy) 411,600 0.00 411,600
2023-01-18 Marda Anup Officer A-Award A Stock Option (Right to Buy) 150,000 0.00 150,000
2023-01-18 Gerard Michael Officer A-Award A Stock Option (Right to Buy) 112,500 0.00 112,500
2023-01-18 Das Arun Officer A-Award A Stock Option (Right to Buy) 150,000 0.00 150,000
2023-01-18 Chang David J. Officer A-Award A Stock Option (Right to Buy) 150,000 0.00 150,000
2023-01-18 Binder Gwendolyn Officer A-Award A Stock Option (Right to Buy) 176,000 0.00 176,000
2022-10-19 Nichtberger Steven Officer P-Purchase A Common Stock 8,127 1.25 10.2K 986,483
2022-10-18 Simon Mark Director P-Purchase A Common Stock 7,000 0.98 6.8K 7,000
2022-10-18 Nichtberger Steven Officer P-Purchase A Common Stock 141,873 0.99 141.0K 978,356
2022-10-18 Marda Anup Officer P-Purchase A Common Stock 50,000 0.99 49.6K 50,000
2022-10-18 Bollard Catherine Director P-Purchase A Common Stock 1,000 0.99 993.50 1,000
2022-10-18 Binder Gwendolyn Officer P-Purchase A Common Stock 20,000 0.99 19.9K 20,000
2022-06-01 Simon Mark Director A-Award A Stock Option (Right to buy) 22,000 1.28 28.2K 22,000
2022-06-01 HENRIQUES RICHARD C JR Director A-Award A Stock Option (Right to buy) 22,000 0.00 22,000
2022-06-01 Brun Scott C. Director A-Award A Stock Option (Right to Buy) 22,000 0.00 22,000
2022-06-01 Bollard Catherine Director A-Award A Stock Option (Right to buy) 22,000 0.00 22,000
2022-01-31 Nichtberger Steven Director / Officer M-Exempt A Common Stock 50,000 1.01 50.5K 836,483
2022-01-18 Nichtberger Steven Director / Officer A-Award A Stock Option (Right to Buy) 380,000 3.21 1.22M 380,000
2022-01-18 Marda Anup Officer A-Award A Stock Option (Right to Buy) 135,000 3.21 433.4K 135,000
2022-01-18 Gerard Michael Officer A-Award A Stock Option (Right to Buy) 75,000 3.21 240.8K 75,000
2022-01-18 Das Arun Officer A-Award A Stock Option (Right to Buy) 100,000 3.21 321.0K 100,000
2022-01-18 Chang David J. Officer A-Award A Stock Option (Right to Buy) 135,000 3.21 433.4K 135,000
2022-01-18 Binder Gwendolyn Officer A-Award A Stock Option (Right to Buy) 160,000 3.21 513.6K 160,000
2022-01-05 Das Arun Officer D Stock Option (Right to Buy) 18,416 11.00 202.6K 0
2021-11-01 5AM Ventures V, L.P. 10% Owner S-Sale D Common Stock 258,456 13.00 3.36M 1,731,119
2021-09-07 5AM Ventures V, L.P. 10% Owner S-Sale D Common Stock 625,000 9.70 6.06M 1,989,575
2021-09-01 Gerard Michael Officer A-Award A Stock Option (Right to Buy) 100,000 10.93 1.09M 100,000
2021-06-24 Brun Scott C. Director A-Award A Stock Option (Right to Buy) 44,000 7.35 323.4K 44,000
2021-06-01 Simon Mark Director A-Award A Stock Option (Right to buy) 22,000 11.00 242.0K 22,000
2021-06-01 HENRIQUES RICHARD C JR Director A-Award A Stock Option (Right to buy) 22,000 11.00 242.0K 22,000
2021-06-01 DANIELS BRIAN Director A-Award A Stock Option (Right to buy) 22,000 11.00 242.0K 22,000
2021-06-01 Bollard Catherine Director A-Award A Stock Option (Right to buy) 22,000 11.00 242.0K 22,000
2021-03-01 Stalter John Brian Officer A-Award A Stock Option (Right to Buy) 64,500 11.47 739.8K 64,500
2021-03-01 Nichtberger Steven Director / Officer A-Award A Stock Option (Right to Buy) 333,500 11.47 3.83M 333,500
2021-03-01 Marda Anup Officer A-Award A Stock Option (Right to Buy) 100,000 11.47 1.15M 100,000
2021-03-01 Chang David J. Officer A-Award A Stock Option (Right to Buy) 113,500 11.47 1.30M 113,500
2021-03-01 Binder Gwendolyn Officer A-Award A Stock Option (Right to Buy) 125,000 11.47 1.43M 125,000
2021-01-12 5AM Ventures V, L.P. 10% Owner S-Sale D Common Stock 74,470 13.00 968.1K 2,614,575
2021-01-08 5AM Ventures V, L.P. 10% Owner S-Sale D Common Stock 264,589 13.00 3.44M 2,689,045
2020-12-10 5AM Ventures V, L.P. 10% Owner S-Sale D Common Stock 261,084 14.75 3.85M 2,953,634
2020-12-08 Nichtberger Steven Director / Officer A-Award A Stock Option (Right to Buy) 93,226 1.01 94.2K 93,226
2020-09-14 Stalter John Brian Officer A-Award A Stock Option (Right to Buy) 60,000 12.01 720.6K 60,000
2020-03-01 Nichtberger Steven Director / Officer A-Award A Stock Option (Right to Buy) 300,000 14.94 4.48M 300,000
2020-03-01 Marda Anup Officer A-Award A Stock Option (Right to Buy) 24,711 14.94 369.2K 24,711
2020-03-01 Chang David J. Officer A-Award A Stock Option (Right to Buy) 38,238 14.94 571.3K 38,238
2020-02-11 DANIELS BRIAN Director A-Award A Stock Option (Right to Buy) 44,000 15.42 678.5K 44,000
2019-12-31 Nichtberger Steven Director / Officer D Common Stock 0 0.00 786,483
2019-12-11 Nichtberger Steven Director / Officer A-Award A Stock Option (Right to Buy) 93,225 1.01 94.2K 93,225
2019-10-29 Simon Mark Director C-Conversion D Series A-1 Preferred Stock 27,217 0.00 0
2019-10-29 Redmile Group, LLC 10% Owner C-Conversion D Series B Convertible Preferred Stock 1,044,568 0.00 0
2019-10-29 Nichtberger Steven Director / Officer C-Conversion D Series A-1 Preferred Stock 90,725 0.00 0
2019-10-29 Flynn James E 10% Owner C-Conversion D Series B Preferred Stock 696,379 0.00 0
2019-10-29 5AM Ventures V, L.P. 10% Owner C-Conversion D Series B Preferred Stock 1,675,532 0.00 0
2019-10-24 Stalter John Brian Officer D Stock Option (Right to Buy) 112,559 9.54 1.07M 0
2019-10-24 Simon Mark Director D Stock Option (Right to Buy) 18,460 6.30 116.3K 0
2019-10-24 Redmile Group, LLC 10% Owner I Series B Convertible Preferred Stock 696,378 0.00 0
2019-10-24 Nichtberger Steven Director / Officer I Common Stock 0 0.00 363,000
2019-10-24 Marda Anup Officer D Stock Option (Right to Buy) 139,282 4.23 589.2K 0
2019-10-24 HENRIQUES RICHARD C JR Director D Stock Option (Right to Buy) 46,428 6.30 292.5K 0
2019-10-24 Flynn James E 10% Owner I Series B Preferred Stock 464,253 0.00 0
2019-10-24 DANIELS BRIAN Director 0 0.00 0
2019-10-24 Chang David J. Officer D Stock Option (Right to Buy) 185,709 6.30 1.17M 0
2019-10-24 Bollard Catherine Director D Stock Option (Right to Buy) 46,428 6.30 292.5K 0
2019-10-24 Binder Gwendolyn Officer D Stock Option (Right to Buy) 66,667 9.54 636.0K 0
2019-10-24 5AM Ventures V, L.P. 10% Owner I Series A Preferred Stock 3,146,551 0.00 0

Executive team

Top executives
Shares Outstanding
96.27M

Executive compensation

Executive compensation (annual)

Executive compensation not available.

CEO compensation breakdown

No CEO compensation history available.

Proxy statements

Proxy statements (DEF 14A)
Filing date Form type Filing
2026-04-28 DEFA14A
2026-04-28 DEF 14A
2026-04-17 PRE 14A
2025-05-13 DEF 14A
2025-04-30 PRE 14A

Recent SEC filings

Recent SEC filings
Filing date Form type Filing
2026-05-15 SC 13G/A
2026-05-14 8-K
2026-05-14 8-K
2026-05-14 10-Q
2026-05-04 8-K
2026-05-04 8-K
2026-05-04 424B5
2026-04-28 DEFA14A
2026-04-28 DEF 14A
2026-04-28 ARS

Executive team

NameTitleCompensationGender
Steven A. Nichtberger Co-Founder, Chairman, Chief Executive Officer & President 1M
David J. Chang FACR Chief Medical Officer 807.1K
Gwendolyn K. Binder President of Science & Technology 774.0K
Anup Marda Chief Financial Officer 548.2K male
Nicolette D. Sherman SPHR Chief Human Resources Officer female
Qing Sarah Yuan Chief Technology Officer
Samik Basu Chief Scientific Officer
Aimee Payne Co-Founder & Co-Chair of Scientific Advisory Board
Steven J. Gavel Chief Commercial Officer male
Heather Harte-Hall Chief Compliance Officer female
Michael C. Milone Co-Founder & Co-Chair of Scientific Advisory Board
Michael Gerard General Counsel & Secretary male
ESG Rating
B
BIOTECHNOLOGY
Rank: 443 out of 662
2026
E (Environmental)
53.9 / 56.3
Company / Sector avg.
S (Social)
59.9 / 62.4
Company / Sector avg.
G (Governance)
61.0 / 60.9
Company / Sector avg.
ESG Total
58.3 / 59.9
Company / Sector avg.
ESG Score History BIOTECHNOLOGY
Benchmark vs Sector
Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend history

Earnings history

Earnings reports

Stock splits