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ArriVent BioPharma, Inc. (AVBP)

USD32.77 +0.23 (+0.71%)
US NASDAQ Healthcare Biotechnology
Address 18 Campus Boulevard Suite 100 19073
Newtown Square, PA, US
CEO Zhengbin Yao
IPO 2024-01-26
CIK 1868279 ISIN US04272N1028

Explore sections of this company profile

Description

ArriVent BioPharma, Inc., a clinical-stage biopharmaceutical company, engages in the identification, development, and commercialization of medicines for the unmet medical needs of patients with cancers. The company’s lead development candidate is firmonertinib, a tyrosine kinase inhibitor that is being evaluated in multiple clinical trials across a range of epidermal growth factor receptor mutations (EGFRm) in non-small cell lung cancer (NSCLC), including a Phase 3 clinical trial for treatment of patients with advanced or metastatic EGFRm NSCLC with exon 20 insertion mutations, as well as Phase 1b clinical trials to treat NSCLC patients with activating EGFRm, including P-loop and-alpha-c-helix compressing (PACC) mutations, and classical EGFRm NSCLC patients. It is also developing ARR-217, an antibody drug conjugate (ADC) for the treatment of gastrointestinal cancers; and ARR-002, ARR-421, and ARR-173 for solid tumors. The company has strategic collaborations with Aarvik Therapeutics Inc., Shanghai Allist Pharmaceuticals Co., Ltd., Beijing InnoCare Pharma Tech Co., Ltd., Jiangsu Alphamab Biopharmaceuticals Co., Ltd., and Lepu Biopharma Co. Ltd. ArriVent BioPharma, Inc. was incorporated in 2021 and is based in Newtown Square, Pennsylvania.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
USD32.77 +0.23 (+0.71%)
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Volume Profile
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Liquidity & share structure
Average Volume
548.0K
Beta
1.30
Float Shares
31.38M
Free Float %
67.7%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
-0.17% -2.10% +13.79% +29.21% +43.42% +43.99% +44.92% +44.85% +44.85% +44.85% +44.85%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
vs.
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Analyst Consensus (6 ratings, all time) Buy
Price Targets & DCF
Current price
32.77
Low 43.00 +31.2%
Consensus 44.00 +34.3%
Median 44.00 +34.3%
High 45.00 +37.3%
DCF (Unlevered) 1.04 -96.8%
DCF (Levered) 1.18 -96.4%

DCF figures are point estimates: small changes in growth or discount-rate assumptions move them materially. Read them as a reference, not a precise target.

Ratings Trend (MoM) 100% Bullish
Rating 2026-05 Change
Strong Buy 0 0
Buy 12 0
Hold 0 0
Sell 0 0
Strong Sell 0 0
Price Target Summary
Period # Analysts Avg Target
Last Month
Last Quarter
Last Year 3
40.33
+23.1%
All Time 7
36.86
+12.5%
Quality scores
Altman Z-Score
30.22
Safe zone
Piotroski F-Score
1 / 9
Weak
MOAT Score
3 / 10
No MOAT
Composite Rating
C
Overall Score
2 / 5
Medium
DCF Score
2 / 5
Medium
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
4 / 5
High
P/E Score
1 / 5
Low
P/Book Score
2 / 5
Medium
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
  • EPS growth Biotechnology: +29.7%
    -68.8% Q1'26: +49.5% (vs Q1'25)
  • FCF margin FCF growth · Biotechnology: +16.2%
  • EBIT margin Biotechnology: +0.0%
  • ROIC Biotechnology: -16.1%
    Q1'26: +0.0% (vs Q1'25)
  • Share dilution Biotechnology: -3.4%
    +22.2% Q1'26: +32.9% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    0.00×
Valuation Multiples From To
Price Forecast (3Y) From To
Model
Adjust
P/E
Theoretical Return — If Invested Today

* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.

DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (1.52) × ERP
WACC = 100% × Ke + 0% × Kd (4.1%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Intrinsic value (base): 1.04 Current price: 32.77
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2023
actual
Dec 2024
actual
Dec 2025
actual
Dec 2026
7 Rev. Ana.
9 EPS Ana.
Dec 2027
6 Rev. Ana.
6 EPS Ana.
Dec 2028
8 Rev. Ana.
6 EPS Ana.
Dec 2029
7 Rev. Ana.
4 EPS Ana.
Dec 2030
7 Rev. Ana.
2 EPS Ana.
Revenue
est: -1.67M (+100.0%)
est: 3.00M (-100.0%)
est: 5.50M (-100.0%)
125.0K
75.2K – 174.8K
-97.7% YoY
39.67M
34.60M – 44.74M
+31,636.1% YoY
140.39M
137.25M – 143.52M
+253.9% YoY
266.77M
160.60M – 373.06M
+90.0% YoY
433.92M
261.21M – 606.79M
+62.7% YoY
EBITDA
-74.59M
-80.49M
-177.53M
— – —
— – —
— – —
— – —
— – —
EBIT
-74.59M
-80.49M
-177.53M
— – —
— – —
— – —
— – —
— – —
Net Income
-69.33M
est: -268.77M (+74.2%)
-80.49M
est: -100.88M (+20.2%)
-166.31M
est: -169.43M (+1.8%)
-143.53M
-162.16M – -124.90M
+15.3% YoY
-123.11M
-126.60M – -119.61M
+14.2% YoY
-84.16M
-127.35M – 67.27M
+31.6% YoY
22.69M
10.95M – 34.45M
+127.0% YoY
124.88M
60.26M – 189.55M
+450.3% YoY
SGA
9.71M
15.30M
24.18M
— – —
— – —
— – —
— – —
— – —
EPS
-2.17
est: -8.54 (+74.6%)
-2.56
est: -2.58 (+0.8%)
-4.32
est: -4.41 (+2.0%)
-3.83
-4.22 – -3.25
+13.1% YoY
-3.21
-3.29 – -3.11
+16.4% YoY
-1.38
-3.31 – 1.75
+56.9% YoY
0.59
0.28 – 0.90
+142.7% YoY
3.25
1.57 – 4.93
+450.3% YoY
Recent Grade Changes (3M)
Date Firm Previous New Grade Action
2026-04-24 Citigroup Buy Buy Maintain
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-11 C 2/5 2/5 1/5 1/5 4/5 1/5 2/5
2026-05-08 C+ 2/5 2/5 1/5 1/5 4/5 1/5 3/5
2026-05-07 C+ 2/5 2/5 1/5 1/5 4/5 1/5 3/5
2026-05-06 C+ 2/5 2/5 1/5 1/5 4/5 1/5 3/5
2026-05-05 C+ 2/5 2/5 1/5 1/5 4/5 1/5 3/5
2026-05-04 C+ 2/5 2/5 1/5 1/5 4/5 1/5 3/5
2026-05-01 C 2/5 2/5 1/5 1/5 3/5 1/5 3/5
2026-04-30 C 2/5 2/5 1/5 1/5 3/5 1/5 3/5
2026-04-29 C 2/5 2/5 1/5 1/5 3/5 1/5 3/5
2026-04-28 C 2/5 2/5 1/5 1/5 3/5 1/5 3/5
2026-04-27 C 2/5 2/5 1/5 1/5 3/5 1/5 3/5
2026-04-24 C+ 2/5 3/5 1/5 1/5 3/5 1/5 3/5
2026-04-23 C+ 2/5 3/5 1/5 1/5 3/5 1/5 3/5
2026-04-22 C+ 2/5 3/5 1/5 1/5 3/5 1/5 3/5
2026-04-21 C+ 2/5 3/5 1/5 1/5 3/5 1/5 3/5
2026-04-20 C+ 2/5 3/5 1/5 1/5 3/5 1/5 3/5
2026-04-17 C 2/5 3/5 1/5 1/5 2/5 1/5 3/5
2026-04-16 C 2/5 3/5 1/5 1/5 2/5 1/5 3/5

Owner Earnings

Owner's Earnings (history)

Owner's Earnings history not available.

Owner alignment
Owner's Earnings TTM
OE per share TTM
Owner's Yield
Maintenance CapEx ratio
Maint CapEx / Avg PPE

Ownership Overview

Ownership breakdown
At a glance
Institutional holders
33
Total invested
25.58M
Insider transactions (90d)
0
Beneficial owners (>5%)
23
Beneficial owners (>5%)
# Reporting person Amount owned % of class Sole voting Shared voting Sole dispositive Shared dispositive Type Citizenship Filing date SEC filing
1 HHLR Advisors, Ltd. 4.48M 13.40% 4.48M IA Cayman Islands 2024-11-14
2 Hillhouse Investment Management, Ltd. 4.48M 13.40% 4.48M IA Cayman Islands 2024-11-14
3 Abigail P. Johnson 2.12M 6.31% 2.12M IN Delaware 2024-11-12
4 FMR LLC 2.12M 6.31% 2.12M 2.12M HC Delaware 2024-11-12
5 Yi Shi 2.05M 6.40% 2.05M 2.05M IN United States 2024-02-13
6 Aaron Cowen 2.04M 6.10% 2.04M 2.04M HC, IN Delaware 2024-12-04
7 Suvretta Capital Management, LLC 2.04M 6.10% 2.04M 2.04M IA, OO Delaware 2024-12-04
8 Ting Jia 1.98M 5.90% 1.98M 1.98M HC, IN Delaware 2024-10-11
9 LAV Fund VI, L.P. (“LAVVI”) 1.97M 6.20% 1.97M 1.97M PN Cayman Islands 2024-02-13
10 (1) BlackRock, Inc. 1.93M 5.80% 1.91M 1.93M HC Delaware 2024-11-08
11 Averill Master Fund, Ltd. 1.82M 5.40% 1.82M 1.82M CO Delaware 2024-12-04
12 Dr. James I. Healy (“Healy”) 1.70M 5.10% 1.70M 1.70M IN Delaware 2024-11-12
13 Dr. Maha Katabi (“Katabi”) 1.70M 5.10% 1.70M 1.70M IN Delaware 2024-11-12
14 Sofinnova Management XI, L.L.C. (“SM XI LLC”) 1.70M 5.10% 1.70M 1.70M OO Delaware 2024-11-12
15 Sofinnova Management XI, L.P. (“SM XI LP”) 1.70M 5.10% 1.70M 1.70M PN Delaware 2024-11-12
16 Sofinnova Venture Partners XI, L.P. (“SVP XI”) 1.70M 5.10% 1.70M 1.70M PN Delaware 2024-11-12
17 Octagon Private Opportunities Fund LP 799.9K 2.40% 799.9K 799.9K PN, OO Delaware 2024-10-11
18 Octagon Investments Master Fund LP 782.0K 2.30% 782.0K 782.0K PN, OO Delaware 2024-10-11
19 Octagon Special Opportunities Fund LP – Series 4 394.5K 1.20% 394.5K 394.5K PN, OO Delaware 2024-10-11
20 LAV Star Limited (“STAR”) 40.0K 0.10% 40.0K 40.0K OO Virgin Islands 2024-02-13
21 Opportunities”) 40.0K 0.10% 40.0K 40.0K OO Virgin Islands 2024-02-13
22 Octagon Capital Advisors LP 2.0K 5.90% 2.0K 2.0K IA, PN Delaware 2024-10-11
23 SCHEDULE 13D 12.00 14.00% 3.03M 3.03M IA 2024-02-05

Institutional Activity (13F)

Institutional ownership trend From To
13F snapshot — 2026 Q1
Investors holding
33
-88 vs prev Q
New positions
5
Closed positions
93
Increased
21
Reduced
4
Put/Call ratio
0.00
Calls held
Puts held
Top institutional holders
# Investor Shares / Δ Mkt value / Δ Own% / Δ Weight% / Δ Avg px / Perf. Hold / Status
1 644.8K +644.8K (+100.0%) 12.97B +13.0B (+100.0%) 1.54% +1.538 pp 12.16% +12.157 pp USD20.12 +0.0% 1 qtrs NEW
2 INFINITUM ASSET MANAGEMENT, LLC 4.12M +255.0K (+6.6%) 82.97M +11.6M (+16.2%) 9.84% +0.608 pp 12.28% -0.848 pp USD22.91 -12.2% 5 qtrs
3 SUVRETTA CAPITAL MANAGEMENT, LLC 4.11M +402.6K (+10.9%) 82.61M +14.3M (+20.9%) 9.80% +0.961 pp 1.69% -0.057 pp USD20.38 -1.3% 8 qtrs
4 HHLR ADVISORS, LTD. 3.93M -555.6K (-12.4%) 79.05M -3.7M (-4.5%) 9.37% -1.326 pp 2.55% +0.524 pp USD18.29 +10.0% 8 qtrs
5 FMR LLC 3.70M +296.0K (+8.7%) 74.52M +11.6M (+18.5%) 8.84% +0.706 pp 0.00% +0.001 pp USD18.74 +7.4% 8 qtrs
6 ORBIMED ADVISORS LLC 3.03M +— (+0.0%) 60.91M +5.1M (+9.1%) 7.22% +0.000 pp 1.25% -0.068 pp USD18.31 +9.9% 8 qtrs
7 BLACKROCK, INC. 2.37M +326.7K (+16.0%) 47.74M +10.0M (+26.5%) 5.66% +0.780 pp 0.00% +0.000 pp USD22.82 -11.8% 6 qtrs
8 OCTAGON CAPITAL ADVISORS LP 1.97M +— (+0.0%) 39.66M +3.3M (+9.1%) 4.70% +0.000 pp 4.81% -0.697 pp USD19.07 +5.5% 8 qtrs
9 NOVO HOLDINGS A/S 1.94M +— (+0.0%) 39.08M +3.2M (+9.1%) 4.63% +0.000 pp 3.03% +0.725 pp USD18.39 +9.4% 8 qtrs
10 VANGUARD GROUP INC 1.87M -160.3K (-7.9%) 37.61M +164.8K (+0.4%) 4.46% -0.382 pp 0.00% +0.000 pp USD20.40 -1.4% 8 qtrs
11 SOFINNOVA INVESTMENTS, INC. 1.70M +— (+0.0%) 34.14M +2.8M (+9.1%) 4.05% +0.000 pp 1.47% -0.240 pp USD18.31 +9.9% 8 qtrs
12 GENERAL CATALYST GROUP MANAGEMENT, LLC 1.49M +— (+0.0%) 30.08M +2.5M (+9.1%) 3.57% +0.000 pp 13.56% +12.656 pp USD18.31 +9.9% 8 qtrs
13 STATE STREET CORP 1.09M +64.4K (+6.3%) 21.97M +3.0M (+15.9%) 2.61% +0.154 pp 0.00% +0.000 pp USD22.19 -9.3% 8 qtrs
14 SC CHINA HOLDING LTD 663.3K +— (+0.0%) 16.72M +3.7M (+28.6%) 1.58% +0.000 pp 0.88% +0.207 pp USD18.31 +9.9% 8 qtrs
15 GEODE CAPITAL MANAGEMENT, LLC 753.5K +37.2K (+5.2%) 15.16M +1.9M (+14.7%) 1.80% +0.089 pp 0.00% +0.000 pp USD20.84 -3.5% 8 qtrs
16 GOLDMAN SACHS GROUP INC 742.5K +310.6K (+71.9%) 14.94M +7.0M (+87.5%) 1.77% +0.741 pp 0.00% +0.001 pp USD21.05 -4.4% 6 qtrs
17 FUND 1 INVESTMENTS, LLC 565.9K -54.0K (-8.7%) 11.38M -51.3K (-0.4%) 1.35% -0.129 pp 1.39% +0.122 pp USD21.28 -5.5% 3 qtrs
18 CITADEL ADVISORS LLC 458.5K +458.5K (+100.0%) 9.23M +9.2M (+100.0%) 1.09% +1.094 pp 0.00% +0.001 pp USD20.12 +0.0% 3 qtrs
19 UBS GROUP AG 450.9K -46.7K (-9.4%) 9.07M -108.2K (-1.2%) 1.08% -0.111 pp 0.00% +0.000 pp USD18.86 +6.7% 8 qtrs
20 MILLENNIUM MANAGEMENT LLC 282.0K -4.2K (-1.5%) 5.67M +394.3K (+7.5%) 0.67% -0.010 pp 0.00% +0.000 pp USD19.55 +2.9% 8 qtrs
21 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 250.6K +7.1K (+2.9%) 5.04M +549.5K (+12.2%) 0.60% +0.017 pp 0.00% +0.000 pp USD20.83 -3.4% 8 qtrs
22 NORTHERN TRUST CORP 245.6K +14.4K (+6.2%) 4.94M +676.4K (+15.9%) 0.59% +0.034 pp 0.00% +0.000 pp USD21.50 -6.4% 8 qtrs
23 SUSQUEHANNA INTERNATIONAL GROUP, LLP 242.8K +242.8K (+100.0%) 4.89M +4.9M (+100.0%) 0.58% +0.579 pp 0.00% +0.001 pp USD20.12 +0.0% 5 qtrs
24 D. E. SHAW & CO., INC. 233.3K +233.3K (+100.0%) 4.69M +4.7M (+100.0%) 0.56% +0.557 pp 0.00% +0.003 pp USD20.12 +0.0% 1 qtrs NEW
25 POINT72 ASSET MANAGEMENT, L.P. 216.7K +216.7K (+100.0%) 4.36M +4.4M (+100.0%) 0.52% +0.517 pp 0.00% +0.005 pp USD20.12 +0.0% 1 qtrs NEW
26 ROSALIND ADVISORS, INC. 215.9K +215.9K (+100.0%) 4.34M +4.3M (+100.0%) 0.52% +0.515 pp 1.53% +1.527 pp USD20.12 +0.0% 1 qtrs NEW
27 SQUAREPOINT OPS LLC 186.5K +58.2K (+45.3%) 3.75M +1.4M (+58.5%) 0.45% +0.139 pp 0.00% +0.002 pp USD21.05 -4.4% 4 qtrs
28 HIDDEN LAKE ASSET MANAGEMENT LP 152.4K -161.6K (-51.5%) 3.07M -2.7M (-47.1%) 0.36% -0.386 pp 0.78% +0.035 pp USD22.87 -12.0% 7 qtrs
29 AFFINITY ASSET ADVISORS, LLC 150.0K +150.0K (+100.0%) 3.02M +3.0M (+100.0%) 0.36% +0.358 pp 0.17% +0.172 pp USD20.12 +0.0% 1 qtrs NEW
30 WOODLINE PARTNERS LP 147.4K -149.5K (-50.4%) 2.97M -2.5M (-45.9%) 0.35% -0.357 pp 0.01% -0.014 pp USD19.45 +3.4% 8 qtrs
31 BARCLAYS PLC 129.2K +87.7K (+211.1%) 2.60M +1.6M (+166.4%) 0.31% +0.190 pp 0.00% +0.000 pp USD20.88 -3.6% 8 qtrs
32 AMERIPRISE FINANCIAL INC 118.5K +118.5K (+100.0%) 2.38M +2.4M (+100.0%) 0.28% +0.283 pp 0.00% +0.001 pp USD20.12 +0.0% 1 qtrs NEW
33 JANE STREET GROUP, LLC 103.3K +103.3K (+100.0%) 2.08M +2.1M (+100.0%) 0.25% +0.246 pp 0.00% +0.000 pp USD20.12 +0.0% 1 qtrs NEW
34 BURKEHILL GLOBAL MANAGEMENT, LP 100.0K +— (+0.0%) 2.01M +167.0K (+9.1%) 0.24% +0.000 pp 0.13% +0.028 pp USD18.45 +9.1% 2 qtrs
35 MARSHALL WACE, LLP 99.0K -81.2K (-45.1%) 1.99M -1.3M (-40.1%) 0.24% -0.194 pp 0.00% -0.002 pp USD18.45 +9.1% 6 qtrs
36 MORGAN STANLEY 97.6K -294.4K (-75.1%) 1.96M -5.3M (-72.9%) 0.23% -0.703 pp 0.00% 0.000 pp USD19.42 +3.6% 8 qtrs
37 WELLINGTON MANAGEMENT GROUP LLP 82.3K +532.0 (+0.7%) 1.66M +147.2K (+9.8%) 0.20% +0.001 pp 0.00% +0.000 pp USD22.84 -11.9% 5 qtrs
38 TWO SIGMA INVESTMENTS, LP 77.5K -14.2K (-15.5%) 1.56M -133.3K (-7.9%) 0.18% -0.034 pp 0.00% 0.000 pp USD18.45 +9.1% 4 qtrs
39 BANK OF NEW YORK MELLON CORP 73.1K +9.8K (+15.5%) 1.47M +303.4K (+26.0%) 0.17% +0.023 pp 0.00% +0.000 pp USD20.89 -3.7% 8 qtrs
40 JPMORGAN CHASE & CO 69.4K +55.4K (+396.0%) 1.40M +1.1M (+440.9%) 0.17% +0.126 pp 0.00% +0.000 pp USD20.61 -2.4% 8 qtrs
41 EXODUSPOINT CAPITAL MANAGEMENT, LP 60.1K +24.0K (+66.4%) 1.21M +543.1K (+81.5%) 0.14% +0.057 pp 0.01% +0.003 pp USD20.19 -0.3% 4 qtrs
42 MOODY ALDRICH PARTNERS LLC 56.7K -2.8K (-4.7%) 1.14M +43.1K (+3.9%) 0.14% -0.007 pp 0.21% +0.005 pp USD21.77 -7.6% 3 qtrs
43 BANK OF AMERICA CORP /DE/ 56.5K +10.5K (+22.9%) 1.14M +288.9K (+34.1%) 0.13% +0.004 pp 0.00% +0.000 pp USD21.17 -5.0% 8 qtrs
44 NUVEEN, LLC 53.6K +6.0K (+12.5%) 1.08M +199.4K (+22.7%) 0.13% +0.014 pp 0.00% +0.000 pp USD18.88 +6.6% 4 qtrs
45 HRT FINANCIAL LP 53.4K +53.4K (+100.0%) 1.07M +1.1M (+100.0%) 0.13% +0.128 pp 0.00% +0.003 pp USD20.12 +0.0% 3 qtrs
46 SG AMERICAS SECURITIES, LLC 51.4K +14.5K (+39.2%) 1.04M +353.0K (+51.8%) 0.12% +0.035 pp 0.00% -0.001 pp USD20.40 -1.4% 6 qtrs
47 SIMPLEX TRADING, LLC 45.6K +38.1K (+511.2%) 916.6K +779.6K (+569.1%) 0.11% +0.091 pp 0.00% +0.000 pp USD19.85 +1.4% 2 qtrs
48 BALYASNY ASSET MANAGEMENT L.P. 43.0K +43.0K (+100.0%) 865.8K +865.8K (+100.0%) 0.10% +0.103 pp 0.00% +0.001 pp USD20.12 +0.0% 3 qtrs
49 SWISS NATIONAL BANK 40.0K +4.5K (+12.7%) 804.8K +149.8K (+22.9%) 0.10% +0.011 pp 0.00% +0.000 pp USD24.04 -16.3% 5 qtrs
50 SECTORAL ASSET MANAGEMENT INC 38.3K -980.0 (-2.5%) 769.7K +45.8K (+6.3%) 0.09% -0.002 pp 0.62% +0.170 pp USD20.62 -2.4% 4 qtrs
51 TWO SIGMA ADVISERS, LP 37.1K -6.7K (-15.3%) 746.5K -61.7K (-7.6%) 0.09% -0.016 pp 0.00% 0.000 pp USD19.63 +2.5% 4 qtrs
52 LOS ANGELES CAPITAL MANAGEMENT LLC 40.3K +40.3K (+100.0%) 744.3K +744.3K (+100.0%) 0.10% +0.096 pp 0.00% +0.003 pp USD20.12 +0.0% 1 qtrs NEW
53 ANSON FUNDS MANAGEMENT LP 35.4K -64.5K (-64.6%) 711.6K -1.1M (-61.4%) 0.08% -0.154 pp 0.07% -0.100 pp USD18.45 +9.1% 2 qtrs
54 ALPS ADVISORS INC 33.9K +33.9K (+100.0%) 682.0K +682.0K (+100.0%) 0.08% +0.081 pp 0.00% +0.004 pp USD20.12 +0.0% 1 qtrs NEW
55 NEOS INVESTMENT MANAGEMENT LLC 32.5K +32.5K (+100.0%) 653.6K +653.6K (+100.0%) 0.08% +0.078 pp 0.00% +0.004 pp USD20.12 +0.0% 1 qtrs NEW
56 WELLS FARGO & COMPANY/MN 32.3K +17.1K (+112.7%) 649.5K +369.4K (+131.9%) 0.08% +0.041 pp 0.00% +0.000 pp USD21.01 -4.2% 8 qtrs
57 TEMA ETFS LLC 32.0K +32.0K (+100.0%) 644.0K +644.0K (+100.0%) 0.08% +0.076 pp 0.05% +0.050 pp USD20.12 +0.0% 1 qtrs NEW
58 RHUMBLINE ADVISERS 31.5K -2.3K (-6.9%) 632.9K +9.2K (+1.5%) 0.08% -0.006 pp 0.00% +0.000 pp USD21.91 -8.2% 8 qtrs
59 RAFFERTY ASSET MANAGEMENT, LLC 28.9K -5.5K (-16.0%) 581.0K -52.9K (-8.3%) 0.07% -0.013 pp 0.00% +0.000 pp USD21.70 -7.3% 6 qtrs
60 ALLIANCEBERNSTEIN L.P. 28.2K +— (+0.0%) 567.4K +47.1K (+9.1%) 0.07% +0.000 pp 0.00% +0.000 pp USD23.50 -14.4% 6 qtrs
61 XTX TOPCO LTD 26.3K +26.3K (+100.0%) 528.2K +528.2K (+100.0%) 0.06% +0.063 pp 0.01% +0.014 pp USD20.12 +0.0% 1 qtrs NEW
62 JUMP FINANCIAL, LLC 24.2K +3.8K (+18.7%) 487.3K +110.9K (+29.5%) 0.06% +0.009 pp 0.01% +0.002 pp USD18.71 +7.5% 2 qtrs
63 WALLEYE CAPITAL LLC 22.1K -5.7K (-20.4%) 445.0K -67.4K (-13.1%) 0.05% -0.014 pp 0.00% -0.001 pp USD19.58 +2.8% 3 qtrs
64 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 21.7K +3.1K (+16.8%) 436.2K +93.8K (+27.4%) 0.05% +0.007 pp 0.00% +0.000 pp USD23.16 -13.1% 8 qtrs
65 DEUTSCHE BANK AG\ 21.5K +1.6K (+7.8%) 433.2K +64.7K (+17.6%) 0.05% +0.004 pp 0.00% +0.000 pp USD23.63 -14.9% 6 qtrs
66 INVESCO LTD. 16.9K +1.9K (+12.5%) 339.9K +62.8K (+22.7%) 0.04% +0.005 pp 0.00% +0.000 pp USD25.92 -22.4% 5 qtrs
67 METLIFE INVESTMENT MANAGEMENT, LLC 16.7K -453.0 (-2.6%) 335.1K +19.5K (+6.2%) 0.04% -0.001 pp 0.00% +0.000 pp USD21.89 -8.1% 8 qtrs
68 BREVAN HOWARD CAPITAL MANAGEMENT LP 16.6K +16.6K (+100.0%) 334.7K +334.7K (+100.0%) 0.04% +0.040 pp 0.00% +0.004 pp USD20.12 +0.0% 3 qtrs
69 PRICE T ROWE ASSOCIATES INC /MD/ 16.1K +1.8K (+12.3%) 325.0K +60.0K (+22.6%) 0.04% +0.004 pp 0.00% +0.000 pp USD22.08 -8.9% 6 qtrs
70 MIRAE ASSET GLOBAL ETFS HOLDINGS LTD. 15.4K +2.1K (+16.1%) 310.4K +66.5K (+27.3%) 0.04% +0.005 pp 0.00% +0.000 pp USD21.85 -7.9% 7 qtrs
71 LEGAL & GENERAL GROUP PLC 15.3K +485.0 (+3.3%) 307.3K +34.5K (+12.6%) 0.04% +0.001 pp 0.00% +0.000 pp USD25.14 -20.0% 8 qtrs
72 DIMENSIONAL FUND ADVISORS LP 14.7K +585.0 (+4.1%) 296.6K +35.4K (+13.6%) 0.04% +0.001 pp 0.00% +0.000 pp USD18.52 +8.6% 2 qtrs
73 QUADRATURE CAPITAL LTD 12.8K +12.8K (+100.0%) 256.8K +256.8K (+100.0%) 0.03% +0.031 pp 0.00% +0.003 pp USD20.12 +0.0% 1 qtrs NEW
74 AQUATIC CAPITAL MANAGEMENT LLC 12.3K +12.3K (+100.0%) 247.6K +247.6K (+100.0%) 0.03% +0.029 pp 0.01% +0.007 pp USD20.12 +0.0% 1 qtrs NEW
75 AQR CAPITAL MANAGEMENT LLC 11.5K -348.0 (-2.9%) 230.9K +12.7K (+5.8%) 0.03% -0.001 pp 0.00% +0.000 pp USD21.77 -7.6% 6 qtrs
76 VIRTU FINANCIAL LLC 11.3K +11.3K (+100.0%) 227.0K +227.0K (+100.0%) 0.03% +0.027 pp 0.01% +0.009 pp USD20.12 +0.0% 3 qtrs
77 INTECH INVESTMENT MANAGEMENT LLC 11.0K +11.0K (+100.0%) 221.5K +221.5K (+100.0%) 0.03% +0.026 pp 0.00% +0.002 pp USD20.12 +0.0% 5 qtrs
78 UBS ASSET MANAGEMENT AMERICAS INC 11.0K +45.0 (+0.4%) 221.5K +19.2K (+9.5%) 0.03% +0.000 pp 0.00% +0.000 pp USD21.76 -7.5% 5 qtrs
79 PROFUND ADVISORS LLC 11.0K +11.0K (+100.0%) 221.0K +221.0K (+100.0%) 0.03% +0.026 pp 0.01% +0.007 pp USD20.12 +0.0% 1 qtrs NEW
80 VIRTUS INVESTMENT ADVISERS, INC. 10.9K +6.1K (+126.2%) 219.2K +130.3K (+146.7%) 0.03% +0.015 pp 0.06% +0.034 pp USD19.40 +3.7% 4 qtrs
81 CITIGROUP INC 8.1K -1.9K (-19.4%) 162.8K -22.4K (-12.1%) 0.02% -0.005 pp 0.00% +0.000 pp USD24.42 -17.6% 8 qtrs
82 PERSISTENT ASSET PARTNERS LTD 8.0K +8.0K (+100.0%) 160.2K +160.2K (+100.0%) 0.02% +0.019 pp 0.07% +0.072 pp USD20.12 +0.0% 1 qtrs NEW
83 POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY 7.9K +1.6K (+26.0%) 158.6K +43.2K (+37.4%) 0.02% +0.004 pp 0.00% +0.000 pp USD25.29 -20.4% 5 qtrs
84 NEW YORK STATE COMMON RETIREMENT FUND 7.8K +— (+0.0%) 156.6K +13.0K (+9.1%) 0.02% +0.000 pp 0.00% +0.000 pp USD22.33 -9.9% 7 qtrs
85 CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD. 6.7K -384.0 (-5.4%) 135.3K +4.1K (+3.2%) 0.02% -0.001 pp 0.01% 0.000 pp USD26.29 -23.5% 5 qtrs
86 BNP PARIBAS ARBITRAGE, SNC 5.5K -36.8K (-87.1%) 110.1K -669.7K (-85.9%) 0.01% -0.088 pp 0.00% 0.000 pp USD18.55 +8.5% 8 qtrs
87 ZURCHER KANTONALBANK (ZURICH CANTONALBANK) 4.7K +1.5K (+45.6%) 95.4K +35.3K (+58.8%) 0.01% +0.004 pp 0.00% +0.000 pp USD18.98 +6.0% 4 qtrs
88 KLP KAPITALFORVALTNING AS 4.3K +1.2K (+38.7%) 86.5K +29.3K (+51.3%) 0.01% +0.003 pp 0.00% +0.000 pp USD24.82 -18.9% 5 qtrs
89 GROUP ONE TRADING, L.P. 2.9K +2.9K (+100.0%) 57.4K +57.4K (+100.0%) 0.01% +0.007 pp 0.00% +0.000 pp USD20.12 +0.0% 1 qtrs NEW
90 QUEST PARTNERS LLC 2.8K -38.6K (-93.2%) 56.3K -708.4K (-92.6%) 0.01% -0.092 pp 0.00% -0.047 pp USD18.45 +9.1% 2 qtrs
91 TOWER RESEARCH CAPITAL LLC (TRC) 2.4K +1.1K (+84.7%) 47.7K +24.0K (+101.4%) 0.01% +0.003 pp 0.00% +0.001 pp USD21.33 -5.7% 8 qtrs
92 AMERITAS INVESTMENT PARTNERS, INC. 2.4K +— (+0.0%) 47.3K +3.9K (+9.1%) 0.01% +0.000 pp 0.00% +0.000 pp USD21.72 -7.4% 8 qtrs
93 RUSSELL INVESTMENTS GROUP, LTD. 2.1K +— (+0.0%) 41.6K +3.5K (+9.1%) 0.00% +0.000 pp 0.00% +0.000 pp USD18.48 +8.9% 3 qtrs
94 MIRAE ASSET GLOBAL INVESTMENTS CO., LTD. 2.0K +438.0 (+27.9%) 40.4K +11.4K (+39.5%) 0.00% +0.001 pp 0.00% +0.000 pp USD23.72 -15.2% 5 qtrs
95 US BANCORP \DE\ 1.1K -176.0 (-13.7%) 22.4K -1.4K (-5.9%) 0.00% 0.000 pp 0.00% +0.000 pp USD21.20 -5.1% 5 qtrs
96 ROYAL BANK OF CANADA 981.00 -16.8K (-94.5%) 21.0K -307.0K (-93.6%) 0.00% -0.040 pp 0.00% 0.000 pp USD18.45 +9.1% 8 qtrs
97 AMALGAMATED BANK 927.00 -36.0 (-3.7%) 19.0K +1.0K (+5.6%) 0.00% 0.000 pp 0.00% +0.000 pp USD20.59 -2.3% 8 qtrs
98 GF FUND MANAGEMENT CO. LTD. 811.00 -62.0 (-7.1%) 16.3K +210.0 (+1.3%) 0.00% 0.000 pp 0.00% +0.000 pp USD25.10 -19.8% 5 qtrs
99 CAITONG INTERNATIONAL ASSET MANAGEMENT CO., LTD 807.00 +807.0 (+100.0%) 16.2K +16.2K (+100.0%) 0.00% +0.002 pp 0.00% +0.004 pp USD20.12 +0.0% 1 qtrs NEW
Ownership breakdown by holder

ETF Ownership

Top ETFs holding this stock Held by 88 ETFs in our universe
# ETF Weight Est. AUM exposure TER
1 Tema Oncology ETF CANC 1.00% 1.42M 0.75%
2 ALPS Medical Breakthroughs ETF SBIO 0.80% 1.71M 0.50%
3 Virtus Biotech Clinical Trials ETF BBC 0.68% 390.9K 0.65%
4 iShares Micro-Cap ETF IWC 0.29% 4.28M 0.60%
5 Global X - S&P Biotech ETF CURE.AX 0.27% 98.6K 0.45%
6 State Street SPDR S&P Biotech ETF XBI 0.27% 29.74M 0.35%
7 Invesco NASDAQ Biotech UCITS ETF SBIO.L 0.11% 499.5K 0.40%
8 Invesco Nasdaq Biotechnology ETF IBBQ 0.11% 80.6K 0.19%
9 iShares Nasdaq US Biotechnology UCITS ETF BTEE.L 0.11% 79.0K 0.35%
10 iShares Nasdaq US Biotechnology UCITS ETF BTEC.L 0.11% 1.18M 0.35%

Insider Activity

Insider Activity — Latest Quarter
Ratio by transactions
0.00
Bearish
Buys
5
Sells
0
Shares acquired
1.10M
Shares disposed
Cash buys
Cash sales
Net activity
+1,100,000
Insider buys vs sells (history) From To
Recent insider transactions From To
Date Person Role Transaction A/D Security Shares Price Value Owned after D/I Filing
2026-02-02 Yao Zhengbin Director / Officer A-Award A Stock Option (right to buy) 550,000 22.67 12.47M 550,000 D
2026-02-02 Lutzker Stuart Director / Officer A-Award A Stock Option (right to buy) 150,000 22.67 3.40M 150,000 D
2026-02-02 LaChapelle Robin Officer A-Award A Stock Option (right to buy) 130,000 22.67 2.95M 130,000 D
2026-02-02 Kung Winston Officer A-Award A Stock Option (right to buy) 140,000 22.67 3.17M 140,000 D
2026-02-02 Kastenmayer James Paul Officer A-Award A Stock Option (right to buy) 130,000 22.67 2.95M 130,000 D
2025-12-10 HILLHOUSE INVESTMENT MANAGEMENT, LTD. 10% Owner S-Sale D Common Stock 555,555 23.37 12.98M 3,929,117 I
2025-07-11 LaChapelle Robin Officer M-Exempt A Common Stock 2,050 2.28 4.7K 126,633 D
2025-06-18 Peterson Kristine Director A-Award A Non-Qualified Stock Option (right to buy) 15,502 24.89 385.8K 15,502 D
2025-06-18 Parsey Merdad Director A-Award A Non-Qualified Stock Option (right to buy) 15,502 24.89 385.8K 15,502 D
2025-06-18 Nolet Chris Director A-Award A Non-Qualified Stock Option (right to buy) 15,502 24.89 385.8K 15,502 D
2025-06-18 Hohneker John Director A-Award A Non-Qualified Stock Option (right to buy) 15,502 24.89 385.8K 15,502 D
2025-04-28 Parsey Merdad Director A-Award A Stock Option (right to buy) 28,346 20.92 593.0K 28,346 D
2024-01-30 ORBIMED ADVISORS LLC Director / 10% Owner P-Purchase A Common Stock 222,222 18.00 4.00M 1,513,664
2024-01-30 HILLHOUSE INVESTMENT MANAGEMENT, LTD. 10% Owner P-Purchase A Common Stock 555,555 18.00 10.00M 4,484,672
2024-01-30 HEALY JAMES Director P-Purchase A Common Stock 444,444 18.00 8.00M 1,696,752
2024-01-30 GORDON CARL L Director / 10% Owner C-Conversion D Series A Preferred Stock 821,827 0.00 0
2024-01-25 ORBIMED ADVISORS LLC Director / 10% Owner I Series B Preferred Stock 469,615 0.00 0
2024-01-25 Nolet Chris Director A-Award A Stock Option (right to buy) 17,884 18.00 321.9K 17,884
2024-01-25 Kung Winston Officer D Stock Option (right to buy) 197,238 7.76 1.53M 0
2024-01-25 Kastenmayer James Paul Officer D Stock Option (right to buy) 32,873 7.76 255.1K 0
2024-01-25 HILLHOUSE INVESTMENT MANAGEMENT, LTD. 10% Owner I Series A Preferred Stock 3,616,041 0.00 0
2024-01-25 HEALY JAMES Director I Series B Preferred Stock 1,252,308 0.00 0
2024-01-25 GORDON CARL L Director / 10% Owner I Series A Preferred Stock 821,827 0.00 0

Executive team

Top executives
Shares Outstanding
46.37M

Executive compensation

Executive compensation (annual)
# Year Executive Salary Bonus Stock award Option award Incentive Other Total % Stock-
based
Filing
1 2025 Zhengbin (Bing) Yao, Ph.D Chief Executive Officer and President 596.7K 8.41M 358.0K 14.0K 9.37M 89.67%
2 2025 Stuart Lutzker, M.D., Ph.D President, Research and Development 515.8K 2.65M 247.6K 14.0K 3.43M 77.35%
3 2025 Winston Kung, MBA Chief Financial Officer and Treasurer 492.4K 2.65M 246.3K 14.0K 3.41M 77.91%
4 2024 Zhengbin (Bing) Yao, Ph.D Chief Executive Officer and President 558.2K 1.60M 238.6K 13.8K 2.41M 66.32%
5 2024 Winston Kung, MBA Chief Financial Officer and Treasurer 469.6K 1.19M 158.8K 13.8K 1.83M 64.95%
6 2024 Stuart Lutzker, M.D., Ph.D President, Research and Development 495.9K 297.5K 179.0K 13.5K 986.0K 30.17%
7 2023 Zhengbin (Bing) Yao, Ph.D Chief Executive Officer and President 536.5K 394.7K 241.4K 13.2K 1.19M 33.29%
8 2023 Stuart Lutzker, M.D., Ph.D President, Research and Development 476.9K 119.3K 219.4K 13.2K 828.8K 14.40%
CEO compensation breakdown

Proxy statements

Proxy statements (DEF 14A)
Filing date Form type Filing
2026-04-28 DEFA14A
2026-04-28 DEF 14A
2025-04-28 DEFA14A
2025-04-28 DEF 14A

Recent SEC filings

Recent SEC filings
Filing date Form type Filing
2026-05-11 8-K
2026-05-11 8-K
2026-05-11 424B5
2026-05-11 10-Q
2026-05-06 SC 13G/A
2026-04-28 DEFA14A
2026-04-28 DEF 14A
2026-04-28 ARS
2026-03-17 8-K
2026-03-05 SC 13G/A

Executive team

NameTitleCompensationGender
Zhengbin Yao Co-Founder, Chairman, President & Chief Executive Officer 968.7K
Stuart Lutzker Co-Founder, President of Research & Development and Director 777.4K
Winston Kung Chief Financial Officer & Treasurer 752.7K male
Robin LaChapelle Co-Founder & Chief Operating Officer 586.5K female
Brent S. Rice Chief Commercial Officer male
Yang Wang Chief Technology Officer female
James Paul Kastenmayer General Counsel & Secretary male
ESG Rating
B
BIOTECHNOLOGY
Rank: 254 out of 710
2026
E (Environmental)
61.3 / 56.3
Company / Sector avg.
S (Social)
67.9 / 62.4
Company / Sector avg.
G (Governance)
65.1 / 60.9
Company / Sector avg.
ESG Total
64.8 / 59.9
Company / Sector avg.
ESG Score History BIOTECHNOLOGY
Benchmark vs Sector
Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend history

Earnings history

Earnings reports

Stock splits