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PharmaEngine, Inc. (4162.TWO)

TWD67.40 +2.80 (+4.33%)
TW TWO Healthcare Biotechnology
Address 10 Minsheng East Road 104
Taipei, TW
CEO Hong-Ren Wang
IPO 2012-06-20
ISIN TW0004162003

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Description

PharmaEngine, Inc. is a biopharmaceutical firm specializing in the creation and advancement of oncology therapeutics, primarily targeting markets in Taiwan and Europe. Its leading drug candidate is ONIVYDE, an innovative liposomal formulation of irinotecan. This topoisomerase 1 inhibitor is designed to treat metastatic pancreatic cancer. The company's pipeline also includes PEP06, currently in Phase I clinical trials for various cancers, and PEP07. PEP07, a Chk1 inhibitor in preclinical development, is being investigated for its ability to induce DNA damage and programmed cell death (apoptosis), leading to "replication catastrophe" in cancer cells. Established in 2002, PharmaEngine, Inc. maintains its corporate headquarters in Taipei, Taiwan.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
TWD67.40 +2.80 (+4.33%)
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Volume Profile
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Liquidity & share structure
Average Volume
548.9K
Beta
0.16
Float Shares
117.85M
Free Float %
83.2%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
-1.45% -5.90% -7.98% -18.86% -23.77% -23.01% -40.70% -42.71% -8.91% -66.86% -10.09%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
vs.
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Price Targets & DCF
Current price
67.40
DCF (Unlevered) 179.34 +166.1%
DCF (Levered) 214.14 +217.7%

DCF figures are point estimates: small changes in growth or discount-rate assumptions move them materially. Read them as a reference, not a precise target.

Ratings Trend (MoM) 0% Bullish
Rating 2026-02 Change
Strong Buy 0 0
Buy 0 0
Hold 1 0
Sell 0 0
Strong Sell 0 0
Quality scores
Altman Z-Score
24.12
Safe zone
Piotroski F-Score
6 / 9
Average
MOAT Score
6 / 10
Developing
Composite Rating
A
Overall Score
4 / 5
High
DCF Score
5 / 5
High
ROE Score
3 / 5
Medium
ROA Score
5 / 5
High
D/E Score
4 / 5
High
P/E Score
2 / 5
Medium
P/Book Score
3 / 5
Medium
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
    -63.9% Q1'26: +28.0% (vs Q1'25)
  • EPS growth Biotechnology: +29.7%
    -77.9% Q1'26: +33.8% (vs Q1'25)
  • FCF margin FCF growth · Biotechnology: +16.2%
    +210.6% Q1'26: +108.7% (vs Q1'25)
  • EBIT margin Biotechnology: +0.0%
    +46.7% Q1'26: +54.2% (vs Q1'25)
  • ROIC Biotechnology: -16.1%
    +128.9% Q1'26: +326.6% (vs Q1'25)
  • Share dilution Biotechnology: -3.4%
    +0.0% Q1'26: -0.2% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    0.10× Q1'26: 0.08× (vs Q1'25)
Valuation Multiples From To
Price Forecast (3Y) From To
Model
Adjust
P/E
Theoretical Return — If Invested Today

* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.

DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (0.17) × ERP
WACC = 99% × Ke + 1% × Kd (4.1%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Intrinsic value (base): 176.46 Current price: 67.40
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2015
actual
Dec 2016
actual
Dec 2017
actual
Dec 2018
actual
Dec 2019
actual
Dec 2020
actual
Dec 2021
actual
Dec 2022
actual
Dec 2023
actual
Dec 2024
actual
Dec 2025
actual
Dec 2026
1 Rev. Ana.
1 EPS Ana.
Dec 2027
1 Rev. Ana.
1 EPS Ana.
Revenue
507.24M
est: 627.67M (-19.2%)
1.13B
est: 1.14B (-0.6%)
853.68M
est: 889.23M (-4.0%)
293.43M
est: 289.60M (+1.3%)
314.04M
est: 330.00M (-4.8%)
1.06B
est: 383.50M (+175.4%)
654.84M
est: 651.00M (+0.6%)
654.38M
est: 656.00M (-0.2%)
767.67M
est: 859.64M (-10.7%)
2.52B
est: 2.45B (+3.2%)
911.42M
est: 910.00M (+0.2%)
1.03B
1.03B – 1.03B
+13.1% YoY
2.94B
2.94B – 2.94B
+185.8% YoY
EBITDA
328.96M
est: 439.39M (-25.1%)
811.12M
est: 799.19M (+1.5%)
616.02M
est: 622.49M (-1.0%)
166.70M
est: 202.73M (-17.8%)
56.49M
est: 231.01M (-75.5%)
765.48M
est: 268.46M (+185.1%)
555.87M
est: 455.72M (+22.0%)
401.15M
est: 459.22M (-12.6%)
347.31M
est: 559.30M (-37.9%)
2.17B
est: 1.59B (+36.6%)
435.51M
est: 592.07M (-26.4%)
669.49M
669.49M – 669.49M
+13.1% YoY
1.91B
1.91B – 1.91B
+185.8% YoY
EBIT
327.33M
est: 432.34M (-24.3%)
808.12M
est: 786.37M (+2.8%)
612.97M
est: 612.50M (+0.1%)
163.77M
est: 199.48M (-17.9%)
49.78M
est: 227.30M (-78.1%)
752.92M
est: 264.15M (+185.0%)
545.61M
est: 448.41M (+21.7%)
392.54M
est: 451.85M (-13.1%)
338.28M
est: 549.79M (-38.5%)
2.16B
est: 1.56B (+38.3%)
425.46M
est: 582.00M (-26.9%)
658.11M
658.11M – 658.11M
+13.1% YoY
1.88B
1.88B – 1.88B
+185.8% YoY
Net Income
394.02M
est: 461.00M (-14.5%)
689.63M
est: 627.84M (+9.8%)
387.06M
est: 442.75M (-12.6%)
129.36M
est: 82.58M (+56.6%)
42.55M
est: 86.36M (-50.7%)
604.28M
est: 95.79M (+530.8%)
426.03M
est: 307.88M (+38.4%)
318.78M
est: 286.41M (+11.3%)
274.65M
est: 359.54M (-23.6%)
1.75B
est: 1.74B (+0.5%)
387.64M
est: 388.64M (-0.3%)
505.23M
505.23M – 505.23M
+30.0% YoY
2.01B
2.01B – 2.01B
+296.9% YoY
SGA
58.34M
est: 92.27M (-36.8%)
129.90M
est: 167.84M (-22.6%)
115.97M
est: 130.73M (-11.3%)
113.23M
est: 42.57M (+166.0%)
118.84M
est: 48.51M (+145.0%)
113.35M
est: 56.38M (+101.0%)
118.40M
est: 95.70M (+23.7%)
140.06M
est: 96.44M (+45.2%)
131.51M
est: 131.38M (+0.1%)
155.37M
est: 373.66M (-58.4%)
124.33M
est: 139.07M (-10.6%)
157.26M
157.26M – 157.26M
+13.1% YoY
449.47M
449.47M – 449.47M
+185.8% YoY
EPS
2.69
est: 3.20 (-16.0%)
4.71
est: 4.36 (+8.0%)
2.63
est: 3.08 (-14.5%)
0.88
est: 0.57 (+53.4%)
0.29
est: 0.60 (-51.7%)
4.15
est: 0.67 (+523.5%)
2.95
est: 2.14 (+37.9%)
2.22
est: 1.99 (+11.6%)
1.91
est: 2.50 (-23.5%)
12.16
est: 12.11 (+0.5%)
2.70
est: 2.70 (+0.0%)
3.51
3.51 – 3.51
+30.0% YoY
13.93
13.93 – 13.93
+296.9% YoY
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-11 A 4/5 5/5 3/5 5/5 4/5 2/5 3/5
2026-05-08 A- 4/5 5/5 3/5 5/5 3/5 2/5 3/5
2026-05-07 A- 4/5 5/5 3/5 5/5 3/5 2/5 3/5
2026-05-06 A- 4/5 5/5 3/5 5/5 3/5 2/5 3/5
2026-05-05 A- 4/5 5/5 3/5 5/5 3/5 2/5 3/5
2026-05-04 A- 4/5 5/5 3/5 5/5 3/5 2/5 3/5
2026-04-30 A- 4/5 5/5 3/5 5/5 3/5 2/5 3/5
2026-04-29 A- 4/5 5/5 3/5 5/5 3/5 2/5 3/5
2026-04-28 A- 4/5 5/5 3/5 5/5 3/5 2/5 3/5
2026-04-27 A- 4/5 5/5 3/5 5/5 3/5 2/5 3/5
2026-04-24 A- 4/5 5/5 3/5 5/5 3/5 2/5 3/5
2026-04-23 A- 4/5 5/5 3/5 5/5 2/5 2/5 3/5
2026-04-22 A- 4/5 5/5 3/5 5/5 2/5 2/5 3/5
2026-04-21 A- 4/5 5/5 3/5 5/5 2/5 2/5 3/5
2026-04-20 A- 4/5 5/5 3/5 5/5 2/5 2/5 3/5
2026-04-17 A- 4/5 5/5 3/5 5/5 2/5 2/5 3/5
2026-04-16 A- 4/5 5/5 3/5 5/5 2/5 2/5 3/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
1.69B
OE per share TTM
11.77
Owner's Yield
20.94%
Maintenance CapEx ratio
29.14%
Maint CapEx / Avg PPE
2.4%

Ownership Overview

Ownership breakdown

Ownership breakdown not available.

At a glance
Institutional holders
Total invested
Insider transactions (90d)
0
Beneficial owners (>5%)
0
Beneficial owners (>5%)

No beneficial ownership filings recorded.

Institutional Activity (13F)

Institutional ownership trend

Institutional history not available.

Top institutional holders

Top holders not available.

ETF Ownership

Top ETFs holding this stock Held by 26 ETFs in our universe
# ETF Weight Est. AUM exposure TER
1 Avantis Emerging Markets Small Cap Equity ETF AVEE 0.02% 20.2K 0.42%
2 Avantis Emerging Markets ex-China Equity ETF AVXC 0.00% 18.1K 0.33%
3 Dimensional - Emerging Markets Value ETF DFEV 0.00% 83.1K 0.46%
4 Vanguard FTSE All-World ex-US Small-Cap ETF VSS 0.00% 576.6K 0.06%
5 Dimensional Emerging Markets Sustainability Core 1 ETF DFSE 0.00% 22.3K 0.44%
6 Dimensional - Emerging Markets Core Equity 2 ETF DFEM 0.00% 245.3K 0.39%
7 Dimensional - Emerging Core Equity Market ETF DFAE 0.00% 200.4K 0.29%
8 Avantis Emerging Markets Equity UCITS ETF USD Acc AVEM.L 0.00% 3.9K 0.35%
9 Dimensional World ex U.S. Core Equity 2 ETF DFAX 0.00% 153.5K 0.28%
10 Vanguard FTSE Emerging Markets Shares ETF VGE.AX 0.00% 17.8K 0.48%

Insider Activity

Insider Activity — Latest Quarter

No insider activity available.

Insider buys vs sells (history)

Insider history not available.

Recent insider transactions

No recent insider transactions.

Executive team

Top executives
EBIT / Employee
9.67M
Shares Outstanding
141.68M

Executive compensation

Executive compensation (annual)

Executive compensation not available.

CEO compensation breakdown

No CEO compensation history available.

Proxy statements

Proxy statements (DEF 14A)

No proxy statements available for this company yet.

Recent SEC filings

Recent SEC filings

No SEC filings available for this company yet.

Executive team

NameTitleCompensationGender
Chi-Hsing Chang Vice President of Corporate Development 4M male
Hong-Ren Wang President & Chief Executive Officer male
Melody Lin Director of Human Resources
Yu Gen Cao Accounting Supervisor
ESG Score History

No data available for this company.

Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend yield history

Dividend history

Earnings history

Earnings reports

Stock splits