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CStone Pharmaceuticals (2616.HK)

HKD5.17 +0.25 (+5.08%)
CN HKSE Healthcare Biotechnology
Address New Bund Times Square 201203
Shanghai, CN
CEO Jianxin Yang
IPO 2019-02-26
ISIN KYG2588M1006

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Also trades on Hong Kong Stock Exchange · 2616.HK (HKD) Other OTC · CSPHF (USD)
Description

CStone Pharmaceuticals is a biopharmaceutical company dedicated to the discovery, development, and commercialization of advanced immuno-oncology and precision medicines. Its mission is to address critical unmet medical needs for cancer patients, both within China and across the globe. The company's market-ready portfolio includes Sugemalimab, a monoclonal antibody targeting programmed death ligand 1 (PD-L1); GAVRETO, an RET inhibitor approved for advanced or metastatic RET-mutant medullary and RET fusion-positive thyroid cancers; and avapritinib, a KIT/PDGFRA inhibitor used to treat adults with unresectable or metastatic gastrointestinal stromal tumors featuring a PDGFRA exon 18 mutation. CStone also maintains a strong pipeline of investigational therapies, such as Nofazinlimab (a PD-1 antibody for hepatocellular carcinoma), Ivosidenib (an isocitrate dehydrogenase 1 (IDH1) inhibitor for adults with relapsed or refractory acute myeloid leukemia with an IDH1 mutation), and Fisogatinib (an FGFR4 inhibitor for hepatocellular carcinoma). Additional pipeline assets include CS1002, CS2006, CS3002, CS3005, CS2007, CS2008, and CS500, primarily for solid tumors, along with CS5001, intended for both solid and hematologic malignancies. Established in 2015, CStone Pharmaceuticals is headquartered in Shanghai, China.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
HKD5.17 +0.25 (+5.08%)
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Volume Profile
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Liquidity & share structure
Average Volume
13M
Beta
0.19
Float Shares
1.10B
Free Float %
69.0%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
+5.78% +3.21% -13.44% +20.51% +31.75% +52.75% +103.28% +181.47% -39.84% -37.40% -37.40%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
vs.
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Price Targets & DCF
Current price
5.17
Ratings Trend (MoM) 100% Bullish
Rating 2026-05 Change
Strong Buy 1 -1
Buy 3 0
Hold 0 0
Sell 0 0
Strong Sell 0 0
Quality scores
Altman Z-Score
-1.08
Distress
Piotroski F-Score
2 / 9
Weak
MOAT Score
0 / 10
No MOAT
Composite Rating
D+
Overall Score
1 / 5
Low
DCF Score
1 / 5
Low
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
2 / 5
Medium
P/E Score
1 / 5
Low
P/Book Score
1 / 5
Low
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
    -33.8% Q4'25: +8.8% (vs Q4'23)
  • EPS growth Biotechnology: +29.7%
    -333.6% Q4'25: +11.3% (vs Q4'23)
  • FCF margin FCF growth · Biotechnology: +16.2%
    -187.6% Q4'25: -25.5% (vs Q4'23)
  • EBIT margin Biotechnology: +0.0%
    -154.3% Q4'25: -63.0% (vs Q4'23)
  • ROIC Biotechnology: -16.1%
    -892.2% Q4'25: -1,190.1% (vs Q4'23)
  • Share dilution Biotechnology: -3.4%
    +8.8% Q4'25: +14.8% (vs Q4'23)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    -0.86× Q4'25: -0.66× (vs Q4'23)
Valuation Multiples From To
DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (0.25) × ERP
WACC = 97% × Ke + 3% × Kd (4.1%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Current price: 5.17
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2021
actual
Dec 2022
actual
Dec 2023
actual
Dec 2024
actual
Dec 2025
actual
Dec 2026
4 Rev. Ana.
2 EPS Ana.
Dec 2027
4 Rev. Ana.
2 EPS Ana.
Dec 2028
3 Rev. Ana.
2 EPS Ana.
Revenue
243.72M
est: 260.66M (-6.5%)
481.36M
est: 471.96M (+2.0%)
463.84M
est: 424.67M (+9.2%)
407.21M
est: 385.86M (+5.5%)
269.58M
est: 216.70M (+24.4%)
477.11M
399.19M – 606.20M
+120.2% YoY
1.52B
467.56M – 4.17B
+219.1% YoY
1.05B
1.00B – 1.10B
-31.1% YoY
EBITDA
-1.90B
est: -199.59M (-849.6%)
-849.66M
est: -361.38M (-135.1%)
-297.23M
est: -325.17M (+8.6%)
-76.43M
est: -295.45M (+74.1%)
-403.85M
est: -165.92M (-143.4%)
-365.32M
-464.17M – -305.66M
-120.2% YoY
-1.17B
-3.20B – -358.01M
-219.1% YoY
-803.64M
-840.07M – -767.21M
+31.1% YoY
EBIT
-1.92B
est: -208.55M (-819.6%)
-894.20M
est: -377.61M (-136.8%)
-355.42M
est: -339.77M (-4.6%)
-95.36M
est: -308.72M (+69.1%)
-415.83M
est: -173.38M (-139.8%)
-381.73M
-485.01M – -319.39M
-120.2% YoY
-1.22B
-3.34B – -374.09M
-219.1% YoY
-839.73M
-877.79M – -801.66M
+31.1% YoY
Net Income
-1.92B
est: -1.79B (-7.3%)
-902.68M
est: -750.34M (-20.3%)
-367.23M
est: -132.38M (-177.4%)
-91.21M
est: -42.96M (-112.3%)
-437.00M
est: -291.44M (-49.9%)
-3.33M
-6.22M – -437.1K
+98.9% YoY
594.79M
-159.75M – 1.60B
+17,970.5% YoY
80.89M
-279.47M – 535.65M
-86.4% YoY
SGA
472.99M
est: 204.20M (+131.6%)
390.48M
est: 369.74M (+5.6%)
248.07M
est: 368.28M (-32.6%)
166.94M
est: 334.62M (-50.1%)
172.36M
est: 187.92M (-8.3%)
413.76M
346.19M – 525.71M
+120.2% YoY
1.32B
405.48M – 3.62B
+219.1% YoY
910.19M
868.93M – 951.45M
-31.1% YoY
EPS
-1.65
est: -1.40 (-17.7%)
-0.77
est: -0.82 (+5.9%)
-0.29
est: -0.10 (-179.3%)
-0.07
est: -0.02 (-257.6%)
-0.31
est: -0.21 (-47.7%)
0.00
0.00 – 0.00
+98.9% YoY
0.52
-0.12 – 1.15
+21,699.9% YoY
0.09
-0.20 – 0.39
-82.2% YoY
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-29 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-05-28 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-05-27 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-05-26 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-05-22 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-05-21 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-05-20 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-05-19 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-05-18 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-05-15 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-05-14 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-05-13 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-05-12 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-05-11 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-05-08 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-07 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-06 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-05 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-04 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-30 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-29 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-28 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-27 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-24 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-23 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-22 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-21 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-20 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-17 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-16 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
-488.88M
OE per share TTM
-0.38
Owner's Yield
-4.15%
Maintenance CapEx ratio
Maint CapEx / Avg PPE
30.5%

Ownership Overview

Ownership breakdown

Ownership breakdown not available.

At a glance
Institutional holders
Total invested
Insider transactions (90d)
0
Beneficial owners (>5%)
0
Beneficial owners (>5%)

No beneficial ownership filings recorded.

Institutional Activity (13F)

Institutional ownership trend

Institutional history not available.

Top institutional holders

Top holders not available.

ETF Ownership

Top ETFs holding this stock Held by 50 ETFs in our universe
# ETF Weight Est. AUM exposure TER
1 iShares MSCI China Small-Cap ETF ECNS 0.43% 279.8K 0.59%
2 UBS Solactive China Technology UCITS ETF USD acc CQQQ.SW 0.10% 362.7K 0.47%
3 UBS Solactive China Technology UCITS ETF hEUR acc CITE.MI 0.09% 336.7K 0.50%
4 iShares MSCI AC Far East ex-Japan Small Cap UCITS ETF ISFE.L 0.06% 42.8K 0.74%
5 State Street SPDR S&P Emerging Markets Small Cap ETF EWX 0.05% 386.1K 0.65%
6 iShares MSCI Emerging Markets Small-Cap ETF EEMS 0.04% 160.6K 0.72%
7 iShares MSCI EM Small Cap UCITS ETF IEMS.L 0.04% 137.0K 0.74%
8 State Street SPDR MSCI Emerging Markets Small Cap UCITS ETF EMSD.L 0.04% 214.7K 0.55%
9 Vanguard FTSE All-World ex-US Small-Cap ETF VSS 0.03% 4.09M 0.06%
10 State Street SPDR S&P China ETF GXC 0.02% 91.3K 0.59%

Insider Activity

Insider Activity — Latest Quarter

No insider activity available.

Insider buys vs sells (history)

Insider history not available.

Recent insider transactions

No recent insider transactions.

Executive team

Top executives
EBIT / Employee
-3.08M
Shares Outstanding
1.60B

Executive compensation

Executive compensation (annual)

Executive compensation not available.

CEO compensation breakdown

No CEO compensation history available.

Proxy statements

Proxy statements (DEF 14A)

No proxy statements available for this company yet.

Recent SEC filings

Recent SEC filings

No SEC filings available for this company yet.

Executive team

NameTitleCompensationGender
Jianxin Yang Chief Executive Officer, President of R&D and Executive Director 8M
Michael J. Choi Chief Business & Strategy Officer male
Qingmei Shi Senior Vice President & Chief Medical Officer
Qinzhou Qi VP and Head of R&D Management & Chief of Staff to the CEO
Weicong Ni CFO & Company Secretary female
Ying Hua Zhang Senior Vice President & Chief Operating Officer female
Yujuan La Senior Vice President of Product Development
ESG Score History

No data available for this company.

Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend history

Earnings history

Earnings reports

Stock splits