Subscribe

CARsgen Therapeutics Holdings Limited (2171.HK)

HKD15.98 +0.48 (+3.10%)
CN HKSE Healthcare Biotechnology
Address Building 12
Shanghai, CN
CEO Zonghai Li
IPO 2021-06-18
ISIN KYG1996C1006

Explore sections of this company profile

Description

CARsgen Therapeutics Holdings Limited, a biopharmaceutical firm founded in Shanghai, China, in 2014, focuses on the discovery, development, and commercialization of advanced chimeric antigen receptor T (CAR-T) cell therapies. The company's efforts are directed toward treating various hematological malignancies and solid tumors across China and the United States. Its robust pipeline includes several key candidates: CT053, an autologous CAR-T product, is currently in a pivotal Phase II trial in China for relapsed/refractory multiple myeloma. Additionally, CT041, another autologous CAR-T, is undergoing Phase Ib/II clinical trials for advanced gastric/gastroesophageal junction and pancreatic cancers in China, and Phase Ib trials for comparable indications in the U.S. CARsgen is also advancing CT011, an autologous CAR-T candidate, through Phase I for patients with Glypican-3 positive advanced hepatocellular carcinoma, and CT032, an autologous CAR-T, in Phase I/II for B cell Non-Hodgkin's lymphoma in China. Furthermore, its pipeline features AB011, a humanized monoclonal antibody in Phase I for CLDN18.2 positive solid tumors in China, as well as CT017, an autologous Glypican-3-targeted CAR-T for hepatocellular carcinoma, and other promising therapies for solid tumors.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
Loading outlook…
Loading forecast...
Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
Loading risk profile…
Price Chart
Averages
Trend
Price
Levels
Draw
HKD15.98 +0.48 (+3.10%)
Loading historical data…
Volume Profile
Loading…
Liquidity & share structure
Average Volume
7M
Beta
0.26
Float Shares
359.14M
Free Float %
62.9%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
+6.47% +6.65% -16.16% +28.08% +4.14% +21.95% -11.01% +63.45% -39.63% -39.63% -39.63%
Rolling Volatility
Loading…
Drawdown
Loading…
Relative Strength
Loading…
Monthly Returns Heatmap
From To
Loading…
Annual Monthly Returns
Loading…
Daily Returns Distribution
vs.
Loading histogram data…

Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Price Targets & DCF
Current price
15.98
DCF (Unlevered) 4.47 -72.0%

DCF figures are point estimates: small changes in growth or discount-rate assumptions move them materially. Read them as a reference, not a precise target.

Ratings Trend (MoM) 50% Bullish
Rating 2026-05 Change
Strong Buy 0 0
Buy 1 0
Hold 0 0
Sell 1 0
Strong Sell 0 0
Quality scores
Altman Z-Score
-1.33
Distress
Piotroski F-Score
4 / 9
Average
MOAT Score
1 / 10
No MOAT
Composite Rating
C-
Overall Score
1 / 5
Low
DCF Score
1 / 5
Low
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
3 / 5
Medium
P/E Score
1 / 5
Low
P/Book Score
1 / 5
Low
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
    +218.7%
  • EPS growth Biotechnology: +29.7%
    +87.5% Q4'25: -13,400.0% (vs Q4'23)
  • FCF margin FCF growth · Biotechnology: +16.2%
    +15.9% Q4'25: +0.0% (vs Q4'23)
  • EBIT margin Biotechnology: +0.0%
    -181.4% Q4'25: -116.3% (vs Q4'23)
  • ROIC Biotechnology: -16.1%
    Q4'25: +122.8% (vs Q4'23)
  • Share dilution Biotechnology: -3.4%
    -0.2% Q4'25: -0.7% (vs Q4'23)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    -0.30× Q4'25: -0.16× (vs Q4'23)
Valuation Multiples From To
DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (0.28) × ERP
WACC = 99% × Ke + 1% × Kd (11.3%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Intrinsic value (base): 4.50 Current price: 15.98
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2023
actual
Dec 2024
actual
Dec 2025
actual
Dec 2026
2 Rev. Ana.
2 EPS Ana.
Dec 2027
2 Rev. Ana.
2 EPS Ana.
Dec 2028
2 Rev. Ana.
2 EPS Ana.
Revenue
est: 5.90M (-100.0%)
39.43M
est: 112.29M (-64.9%)
125.66M
est: 118.95M (+5.6%)
728.25M
351.36M – 1.11B
+512.2% YoY
1.68B
840.18M – 2.51B
+130.1% YoY
2.48B
2.44B – 2.52B
+47.8% YoY
EBITDA
-717.64M
est: -1.18M (-60,742.8%)
-686.61M
est: -22.46M (-2,957.3%)
-203.91M
est: -23.79M (-757.1%)
-145.65M
-221.03M – -70.27M
-512.2% YoY
-335.10M
-502.16M – -168.04M
-130.1% YoY
-495.43M
-503.21M – -487.65M
-47.8% YoY
EBIT
-785.05M
est: -1.18M (-66,458.0%)
-751.75M
est: -22.46M (-3,247.3%)
-227.90M
est: -23.79M (-857.9%)
-145.65M
-221.03M – -70.27M
-512.2% YoY
-335.10M
-502.16M – -168.04M
-130.1% YoY
-495.43M
-503.21M – -487.65M
-47.8% YoY
Net Income
-747.79M
est: -646.38M (-15.7%)
-798.13M
est: -476.22M (-67.6%)
-97.86M
est: -715.75M (+86.3%)
-72.61M
-85.89M – 252.66M
+89.9% YoY
693.69M
229.03M – 1.16B
+1,055.3% YoY
1.18B
251.94M – 2.11B
+69.9% YoY
SGA
133.31M
est: 9.94M (+1,241.0%)
52.02M
est: 189.29M (-72.5%)
26.07M
est: 200.52M (-87.0%)
1.23B
592.28M – 1.86B
+512.2% YoY
2.82B
1.42B – 4.23B
+130.1% YoY
4.18B
4.11B – 4.24B
+47.8% YoY
EPS
-1.34
est: -1.16 (-15.5%)
-1.44
est: -1.25 (-14.8%)
-0.18
est: -1.30 (+86.1%)
0.15
-0.16 – 0.46
+111.6% YoY
1.26
0.41 – 2.10
+731.9% YoY
2.14
0.46 – 3.81
+69.9% YoY
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-29 C- 1/5 1/5 1/5 1/5 3/5 1/5 1/5
2026-05-28 C- 1/5 1/5 1/5 1/5 3/5 1/5 1/5
2026-05-27 C- 1/5 1/5 1/5 1/5 3/5 1/5 1/5
2026-05-26 C- 1/5 1/5 1/5 1/5 3/5 1/5 1/5
2026-05-22 C- 1/5 1/5 1/5 1/5 3/5 1/5 1/5
2026-05-21 C- 1/5 1/5 1/5 1/5 3/5 1/5 1/5
2026-05-20 C- 1/5 1/5 1/5 1/5 3/5 1/5 1/5
2026-05-19 C- 1/5 1/5 1/5 1/5 3/5 1/5 1/5
2026-05-18 C- 1/5 1/5 1/5 1/5 3/5 1/5 1/5
2026-05-15 C- 1/5 1/5 1/5 1/5 3/5 1/5 1/5
2026-05-14 C- 1/5 1/5 1/5 1/5 3/5 1/5 1/5
2026-05-13 C- 1/5 1/5 1/5 1/5 3/5 1/5 1/5
2026-05-12 C- 1/5 1/5 1/5 1/5 3/5 1/5 1/5
2026-05-11 C- 1/5 1/5 1/5 1/5 3/5 1/5 1/5
2026-05-08 C- 1/5 1/5 1/5 1/5 3/5 1/5 1/5
2026-05-07 C- 1/5 1/5 1/5 1/5 3/5 1/5 1/5
2026-05-06 C- 1/5 1/5 1/5 1/5 3/5 1/5 1/5
2026-05-05 C- 1/5 1/5 1/5 1/5 3/5 1/5 1/5
2026-05-04 C- 1/5 1/5 1/5 1/5 3/5 1/5 1/5
2026-04-30 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-04-29 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-04-28 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-04-27 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-04-24 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-04-23 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-04-22 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-04-21 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-04-20 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-04-17 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-04-16 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
166.69M
OE per share TTM
0.30
Owner's Yield
1.67%
Maintenance CapEx ratio
Maint CapEx / Avg PPE
905.0%

Ownership Overview

Ownership breakdown

Ownership breakdown not available.

At a glance
Institutional holders
Total invested
Insider transactions (90d)
0
Beneficial owners (>5%)
0
Beneficial owners (>5%)

No beneficial ownership filings recorded.

Institutional Activity (13F)

Institutional ownership trend

Institutional history not available.

Top institutional holders

Top holders not available.

ETF Ownership

Top ETFs holding this stock Held by 51 ETFs in our universe
# ETF Weight Est. AUM exposure TER
1 iShares MSCI China Small-Cap ETF ECNS 0.48% 312.3K 0.59%
2 iShares MSCI AC Far East ex-Japan Small Cap UCITS ETF ISFE.L 0.06% 44.4K 0.74%
3 State Street SPDR S&P Emerging Markets Small Cap ETF EWX 0.05% 365.1K 0.65%
4 iShares MSCI EM Small Cap UCITS ETF IEMS.L 0.04% 150.1K 0.74%
5 iShares MSCI Emerging Markets Small-Cap ETF EEMS 0.04% 154.4K 0.72%
6 State Street SPDR MSCI Emerging Markets Small Cap UCITS ETF EMSD.L 0.04% 236.0K 0.55%
7 State Street SPDR S&P China ETF GXC 0.03% 115.1K 0.59%
8 Vanguard FTSE All-World ex-US Small-Cap ETF VSS 0.02% 2.97M 0.06%
9 iShares MSCI EM IMI Screened UCITS ETF SEDM.L 0.01% 102.3K 0.18%
10 Vanguard FTSE Emerging Markets All Cap Index ETF VEE.TO 0.01% 221.9K 0.26%

Insider Activity

Insider Activity — Latest Quarter

No insider activity available.

Insider buys vs sells (history)

Insider history not available.

Recent insider transactions

No recent insider transactions.

Executive team

Top executives
EBIT / Employee
-490.1K
Shares Outstanding
570.53M

Executive compensation

Executive compensation (annual)

Executive compensation not available.

CEO compensation breakdown

No CEO compensation history available.

Proxy statements

Proxy statements (DEF 14A)

No proxy statements available for this company yet.

Recent SEC filings

Recent SEC filings

No SEC filings available for this company yet.

Executive team

NameTitleCompensationGender
Huamao Wang Co-Founder, Chief Operating Officer & Executive Director 2M
Zonghai Li Co-Founder, Chief Executive Officer, Chief Scientific Officer & Chairman of the Board 2M
Hua Jiang Executive Director 1M
Haiou Chen Executive Vice President male
Wing Yat Lui Company Secretary male
ESG Score History

No data available for this company.

Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

Share your view on this stock and instantly see how the community has voted over the last 6 months.

These are community opinions and do not constitute buy or sell advice to act on. The results shown are based on aggregated opinions and are not an investment recommendation, nor do they intend to influence any investment decision.

Dividend history

Earnings history

Earnings reports

Stock splits