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Zymeworks Inc. (ZYME)
USD24.71
+0.05 (+0.20%)
CA NASDAQ Healthcare Biotechnology
Address
114 East 4th Avenue V5T 1G4
Middletown, BC, CA
Middletown, BC, CA
CEO
Kenneth H. Galbraith
Website
zymeworks.com
IPO
2017-04-28
CIK 1937653 ISIN US98985Y1082
Description
Zymeworks Inc. is a biopharmaceutical firm in the clinical development phase, dedicated to identifying, advancing, and bringing to market biological therapies aimed at combating cancer. Its pipeline features two primary experimental treatments: zanidatamab, a cutting-edge bispecific antibody currently undergoing Phase 1 and Phase 2 studies for various malignancies such as those affecting the biliary tract, gastroesophageal region (adenocarcinomas), breast, and colon; and ZW49, an antibody-drug conjugate targeting two sites on the human epidermal growth factor receptor 2 (HER2), which is in Phase 1 trials for advanced or spreading tumors that express HER2. Zymeworks maintains significant alliances with several pharmaceutical leaders, including Merck Sharp & Dohme Research Ltd., Eli Lilly and Company, Bristol-Myers Squibb company, GlaxoSmithKline Intellectual Property Development Ltd., Daiichi Sankyo Co., Ltd., Janssen Biotech, Inc., BeiGene, Ltd., and Exelixis, Inc. Furthermore, it engages in cooperative research and licensing agreements with LEO Pharma A/S, specifically for the exploration, advancement, and market introduction of bispecific antibodies, and with Iconic Therapeutics, Inc. Established in 2003, Zymeworks Inc. operates from its headquarters located in Vancouver, Canada.
Market Cap & Enterprise Value
Merger & Acquisition History
No mergers or acquisitions recorded for this company.
Technical Outlook
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Signal Summary
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| Indicator | 1D | 1W | 2W | 3W | 1M |
|---|
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
USD24.71
+0.05 (+0.20%)
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Volume Profile
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Liquidity & share structure
Average Volume
664.6K
Beta
1.13
Float Shares
70.03M
Free Float %
94.2%
Price Performance
| 1D | 5D | 1M | 3M | 6M | YTD | 1Y | 3Y | 5Y | 10Y | Max |
|---|---|---|---|---|---|---|---|---|---|---|
| -0.54% | -13.62% | -9.19% | +3.15% | +23.39% | -9.23% | +98.84% | +142.39% | -13.34% | +83.85% | +83.85% |
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From
To
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Annual Monthly Returns
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Daily Returns Distribution
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Revenue flow
Revenue by geography
Revenue by segment
From
To
Revenue composition
From
To
By product
By geography
Financial Statements
Select metrics from the tables below to build your comparison.
Income Statement
Balance Sheet
Cash Flow Statement
Key Metrics
Financial Ratios
Employees
Financial Growth (CAGR)
Market Data
Analyst Consensus (20 ratings, all time)
Buy
Price Targets & DCF
Current price
24.71
Low
32.00
+29.5%
Consensus
38.33
+55.1%
Median
38.50
+55.8%
High
48.00
+94.3%
Ratings Trend (MoM)
100% Bullish
| Rating | 2026-05 | Change |
|---|---|---|
| Strong Buy | 2 | 0 |
| Buy | 12 | 0 |
| Hold | 0 | 0 |
| Sell | 0 | 0 |
| Strong Sell | 0 | 0 |
Price Target Summary
| Period | # Analysts | Avg Target |
|---|---|---|
| Last Month | — | — |
| Last Quarter | 1 |
48.00
+94.3%
|
| Last Year | 8 |
35.13
+42.2%
|
| All Time | 17 |
26.65
+7.9%
|
Quality scores
Altman Z-Score
-2.26
Distress
Piotroski F-Score
2 / 9
Weak
MOAT Score
0 / 10
No MOAT
Composite Rating
C-
Overall Score
1 / 5
Low
DCF Score
1 / 5
Low
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
3 / 5
Medium
P/E Score
1 / 5
Low
P/Book Score
1 / 5
Low
Operational MOAT
✗ Below peers
-
Revenue growth Biotechnology: +1.6%+38.9% ★ Q1'26: -91.1% (vs Q1'25)
-
EPS growth Biotechnology: +29.7%+33.3% ★ Q1'26: -96.7% (vs Q1'25)
-
FCF margin FCF growth · Biotechnology: +16.2%-72.5% Q1'26: -1,898,588.0% (vs Q1'25)
-
EBIT margin Biotechnology: +0.0%-87.3% Q1'26: -1,956.7% (vs Q1'25)
-
ROIC Biotechnology: -16.1%-159.6% Q1'26: +0.1% (vs Q1'25)
-
Share dilution Biotechnology: -3.4%-0.7% ★ Q1'26: -0.7% (vs Q1'25)
-
Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×-0.22× Q1'26: -96.24× (vs Q1'25)
Valuation Multiples
From
To
Price Forecast (3Y)
From
To
Theoretical Return — If Invested Today
* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.
Consensus Estimates
| Metric |
Dec 2017 actual |
Dec 2018 actual |
Dec 2019 actual |
Dec 2020 actual |
Dec 2021 actual |
Dec 2022 actual |
Dec 2023 actual |
Dec 2024 actual |
Dec 2025 actual |
Dec 2026 9 Rev. Ana. 8 EPS Ana. |
Dec 2027 9 Rev. Ana. 7 EPS Ana. |
Dec 2028 8 Rev. Ana. 6 EPS Ana. |
Dec 2029 7 Rev. Ana. 4 EPS Ana. |
Dec 2030 7 Rev. Ana. 2 EPS Ana. |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue |
51.76M
est: 2.00M (+2,488.1%)
|
53.02M
est: 56.17M (-5.6%)
|
29.54M
est: 33.84M (-12.7%)
|
38.95M
est: 33.86M (+15.0%)
|
26.68M
est: 15.63M (+70.7%)
|
412.48M
est: 240.59M (+71.4%)
|
76.01M
est: 62.71M (+21.2%)
|
76.30M
est: 89.49M (-14.7%)
|
105.97M
est: 122.83M (-13.7%)
|
289.70M
97.56M – 523.50M
+135.9% YoY
|
205.64M
143.04M – 310.02M
-29.0% YoY
|
198.27M
191.37M – 205.16M
-3.6% YoY
|
305.35M
171.69M – 461.45M
+54.0% YoY
|
399.72M
224.76M – 604.07M
+30.9% YoY
|
| EBITDA |
-6.08M
est: -1.46M (-316.1%)
|
-30.76M
est: -41.06M (+25.1%)
|
-148.12M
est: -24.73M (-498.9%)
|
-183.77M
est: -103.07M (-78.3%)
|
-206.09M
est: -246.52M (+16.4%)
|
142.49M
est: -271.17M (+152.5%)
|
-120.70M
est: -42.93M (-181.2%)
|
-108.62M
est: -61.26M (-77.3%)
|
-81.43M
est: -84.09M (+3.2%)
|
-198.33M
-358.39M – -66.79M
-135.9% YoY
|
-140.78M
-212.24M – -97.93M
+29.0% YoY
|
-135.73M
-140.45M – -131.01M
+3.6% YoY
|
-209.04M
-315.91M – -117.54M
-54.0% YoY
|
-273.64M
-413.54M – -153.87M
-30.9% YoY
|
| EBIT |
-7.93M
est: -1.47M (-438.3%)
|
-33.36M
est: -41.38M (+19.4%)
|
-150.43M
est: -24.93M (-503.4%)
|
-187.12M
est: -174.98M (-6.9%)
|
-215.67M
est: -216.73M (+0.5%)
|
130.49M
est: -238.40M (+154.7%)
|
-138.01M
est: -44.61M (-209.4%)
|
-119.82M
est: -63.66M (-88.2%)
|
-92.54M
est: -87.38M (-5.9%)
|
-206.09M
-372.41M – -69.41M
-135.9% YoY
|
-146.29M
-220.54M – -101.76M
+29.0% YoY
|
-141.04M
-145.95M – -136.14M
+3.6% YoY
|
-217.22M
-328.27M – -122.14M
-54.0% YoY
|
-284.35M
-429.72M – -159.89M
-30.9% YoY
|
| Net Income |
-10.41M
est: -127.94M (+91.9%)
|
-36.56M
est: -110.02M (+66.8%)
|
-145.44M
est: -214.96M (+32.3%)
|
-180.55M
est: -114.30M (-58.0%)
|
-211.84M
est: -254.98M (+16.9%)
|
124.34M
est: 186.08M (-33.2%)
|
-118.67M
est: -112.51M (-5.5%)
|
-122.70M
est: -116.91M (-4.9%)
|
-81.13M
est: -81.13M (+0.0%)
|
129.08M
-115.04M – 468.78M
+259.1% YoY
|
-3.44M
-36.02M – 119.00M
-102.7% YoY
|
-1.97M
-179.25M – 235.11M
+42.8% YoY
|
68.88M
29.69M – 114.66M
+3,602.5% YoY
|
90.41M
38.96M – 150.49M
+31.2% YoY
|
| SGA |
18.55M
est: 1.97M (+841.9%)
|
29.46M
est: 55.31M (-46.7%)
|
62.88M
est: 33.32M (+88.7%)
|
55.18M
est: 33.34M (+65.5%)
|
42.60M
est: 15.39M (+176.9%)
|
73.40M
est: 53.85M (+36.3%)
|
70.40M
est: 51.26M (+37.3%)
|
61.50M
est: 73.15M (-15.9%)
|
61.50M
est: 100.41M (-38.7%)
|
236.81M
79.75M – 427.93M
+135.9% YoY
|
168.10M
116.93M – 253.42M
-29.0% YoY
|
162.07M
156.43M – 167.71M
-3.6% YoY
|
249.60M
140.35M – 377.21M
+54.0% YoY
|
326.74M
183.72M – 493.79M
+30.9% YoY
|
| EPS |
-0.49
est: -1.69 (+70.9%)
|
-1.26
est: -1.45 (+13.1%)
|
-3.83
est: -2.83 (-35.2%)
|
-3.58
est: -4.20 (+14.8%)
|
-4.06
est: -4.55 (+10.8%)
|
1.91
est: -0.06 (+3,287.7%)
|
-1.72
est: -1.53 (-12.4%)
|
-1.62
est: -1.44 (-12.3%)
|
-1.08
est: -0.95 (-13.5%)
|
1.23
-1.53 – 6.22
+229.7% YoY
|
0.37
-0.48 – 1.58
-70.0% YoY
|
0.31
-2.38 – 3.12
-15.3% YoY
|
0.91
0.39 – 1.52
+191.0% YoY
|
1.20
0.52 – 2.00
+31.2% YoY
|
Historical Ratings (3M)
| Date | Rating | Overall | DCF | ROE | ROA | D/E | P/E | P/B |
|---|---|---|---|---|---|---|---|---|
| 2026-05-07 | C- | 1/5 | 1/5 | 1/5 | 1/5 | 3/5 | 1/5 | 1/5 |
| 2026-05-06 | C- | 1/5 | 1/5 | 1/5 | 1/5 | 3/5 | 1/5 | 1/5 |
| 2026-05-05 | C- | 1/5 | 1/5 | 1/5 | 1/5 | 3/5 | 1/5 | 1/5 |
| 2026-05-04 | C- | 1/5 | 1/5 | 1/5 | 1/5 | 3/5 | 1/5 | 1/5 |
| 2026-05-01 | D+ | 1/5 | 1/5 | 1/5 | 1/5 | 2/5 | 1/5 | 1/5 |
| 2026-04-30 | D+ | 1/5 | 1/5 | 1/5 | 1/5 | 2/5 | 1/5 | 1/5 |
| 2026-04-29 | D+ | 1/5 | 1/5 | 1/5 | 1/5 | 2/5 | 1/5 | 1/5 |
| 2026-04-28 | D+ | 1/5 | 1/5 | 1/5 | 1/5 | 2/5 | 1/5 | 1/5 |
| 2026-04-27 | D+ | 1/5 | 1/5 | 1/5 | 1/5 | 2/5 | 1/5 | 1/5 |
| 2026-04-24 | D+ | 1/5 | 1/5 | 1/5 | 1/5 | 2/5 | 1/5 | 1/5 |
| 2026-04-23 | D+ | 1/5 | 1/5 | 1/5 | 1/5 | 2/5 | 1/5 | 1/5 |
| 2026-04-22 | D+ | 1/5 | 1/5 | 1/5 | 1/5 | 2/5 | 1/5 | 1/5 |
| 2026-04-21 | D+ | 1/5 | 1/5 | 1/5 | 1/5 | 2/5 | 1/5 | 1/5 |
| 2026-04-20 | D+ | 1/5 | 1/5 | 1/5 | 1/5 | 2/5 | 1/5 | 1/5 |
| 2026-04-17 | D+ | 1/5 | 1/5 | 1/5 | 1/5 | 2/5 | 1/5 | 1/5 |
| 2026-04-16 | D+ | 1/5 | 1/5 | 1/5 | 1/5 | 2/5 | 1/5 | 1/5 |
Owner Earnings
Owner's Earnings (history)
From
To
Owner alignment
Owner's Earnings TTM
-45.75B
OE per share TTM
-612.53
Owner's Yield
-2,303.55%
Maintenance CapEx ratio
—
Maint CapEx / Avg PPE
26.6%
Ownership Overview
Ownership breakdown
At a glance
Institutional holders
41
Total invested
73.38M
Insider transactions (90d)
0
Beneficial owners (>5%)
35
Beneficial owners (>5%)
| # | Reporting person | Amount owned | % of class | Sole voting | Shared voting | Sole dispositive | Shared dispositive | Type | Citizenship | Filing date | SEC filing |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Jeremy C. Green | 6.08M | 10.10% | — | 6.08M | — | — | HC, IN | Delaware | 2022-10-17 | ↗ |
| 2 | Redmile Group, LLC | 6.08M | 10.10% | — | 6.08M | — | — | IA, OO | Delaware | 2022-10-17 | ↗ |
| 3 | Morgan Stanley | 5.58M | 8.90% | — | — | — | 13.00 | HC, CO | Delaware. | 2023-02-10 | ↗ |
| 4 | Morgan Stanley Capital Services LLC | 5.55M | 8.80% | — | — | — | 13.00 | BD, CO | Delaware. | 2023-02-10 | ↗ |
| 5 | Baker Bros. Advisors (GP) LLC | 4.91M | 9.99% | 4.91M | — | 4.91M | — | HC, OO | Delaware | 2021-02-05 | ↗ |
| 6 | Baker Bros. Advisors LP | 4.91M | 9.99% | 4.91M | — | 4.91M | — | IA, PN | Delaware | 2021-02-05 | ↗ |
| 7 | Felix J. Baker | 4.91M | 9.99% | 4.91M | — | 4.91M | — | HC, IN | Delaware | 2021-02-05 | ↗ |
| 8 | Julian C. Baker | 4.91M | 9.99% | 4.91M | — | 4.91M | — | HC, IN | Delaware | 2021-02-05 | ↗ |
| 9 | (1) BlackRock, Inc. | 3.92M | 5.60% | 3.82M | — | 3.92M | — | HC | Delaware | 2024-01-29 | ↗ |
| 10 | David Rosen | 3.92M | 5.51% | — | 3.92M | — | — | IN | State of Delaware | 2024-11-13 | ↗ |
| 11 | Rubric Capital Management LP | 3.92M | 5.51% | — | 3.92M | — | — | IA, PN | State of Delaware | 2024-11-13 | ↗ |
| 12 | Joseph Edelman | 3.68M | 6.60% | — | 3.68M | — | 3.68M | IN | Delaware | 2022-02-15 | ↗ |
| 13 | Perceptive Advisors LLC | 3.68M | 6.60% | — | 3.68M | — | 3.68M | IA | Delaware | 2022-02-15 | ↗ |
| 14 | Perceptive Life Sciences Master Fund, Ltd. | 3.68M | 6.60% | — | 3.68M | — | 3.68M | CO | Delaware | 2022-02-15 | ↗ |
| 15 | Abigail P. Johnson | 3.49M | 7.50% | — | — | 3.49M | — | IN | United States of America | 2022-02-09 | ↗ |
| 16 | FMR LLC | 3.49M | 7.50% | 210.8K | — | 3.49M | — | HC | Delaware | 2022-02-09 | ↗ |
| 17 | Redmile Biopharma Investments III, L.P. | 3.47M | 5.80% | — | 3.47M | — | — | PN | Delaware | 2022-10-17 | ↗ |
| 18 | All Blue Falcons FZE | 3.42M | 5.92% | 3.42M | — | 3.42M | 10.00 | OO | United Arab Emirates | 2022-04-22 | ↗ |
| 19 | Daniel Edward Llewellen Cookson | 3.42M | 5.92% | 3.42M | — | 3.42M | 10.00 | HC, IN | United Kingdom | 2022-04-22 | ↗ |
| 20 | Wellington Group Holdings LLP | 2.86M | 6.14% | — | 2.44M | — | — | HC | Delaware | 2022-02-04 | ↗ |
| 21 | Wellington Investment Advisors Holdings LLP | 2.86M | 6.14% | — | 2.44M | — | — | HC | Delaware | 2022-02-04 | ↗ |
| 22 | Wellington Management Group LLP | 2.86M | 6.14% | — | 2.44M | — | — | HC | Delaware | 2022-02-04 | ↗ |
| 23 | Eventide Asset Management, LLC | 2.82M | 6.10% | 2.82M | — | 2.82M | — | IA | Delaware | 2022-02-14 | ↗ |
| 24 | Finny Kuruvilla, M.D. Ph. D. | 2.82M | 6.10% | — | 2.82M | — | — | HC, IN | United States | 2022-02-14 | ↗ |
| 25 | Robin C. John | 2.82M | 6.10% | — | 2.82M | — | — | HC, IN | United States | 2022-02-14 | ↗ |
| 26 | BANK OF AMERICA CORP /DE/560906609 | 2.67M | 5.70% | — | 2.67M | — | 2.67M | HC | Delaware | 2022-01-31 | ↗ |
| 27 | Israel A. Englander | 2.51M | 4.40% | — | 2.51M | — | 2.51M | IN | — | 2022-02-10 | ↗ |
| 28 | Millennium Group Management LLC | 2.51M | 4.40% | — | 2.51M | — | 2.51M | OO | — | 2022-02-10 | ↗ |
| 29 | Millennium Management LLC | 2.51M | 4.40% | — | 2.51M | — | 2.51M | OO | — | 2022-02-10 | ↗ |
| 30 | CREDIT SUISSE AG/000000000 | 2.46M | 5.29% | — | 2.46M | — | 2.46M | BK, HC | — | 2022-02-14 | ↗ |
| 31 | GOLDMAN SACHS & CO. LLC | 2.42M | 5.20% | — | 2.41M | — | 2.42M | BD, IA, OO | Delaware | 2022-02-11 | ↗ |
| 32 | THE GOLDMAN SACHS GROUP, INC. | 2.42M | 5.20% | — | 2.41M | — | 2.42M | HC, CO | Delaware | 2022-02-11 | ↗ |
| 33 | Dr. Jeffrey R. Jay, M.D. | 799.7K | 1.75% | — | 799.7K | — | — | HC, IN | USA | 2021-02-16 | ↗ |
| 34 | Great Point Partners, LLC | 799.7K | 1.75% | — | 799.7K | — | — | IA, OO | USA | 2021-02-16 | ↗ |
| 35 | Mr. Ortav Yehudai | 799.7K | 1.75% | — | 799.7K | — | — | HC, IN | USA | 2021-02-16 | ↗ |
Institutional Activity (13F)
Institutional ownership trend
From
To
13F snapshot — 2026 Q1
Investors holding
41
-177 vs prev Q
New positions
5
Closed positions
172
Increased
18
Reduced
10
Put/Call ratio
0.00
Calls held
—
Puts held
—
Top institutional holders
| # | Investor | Shares / Δ | Mkt value / Δ | Own% / Δ | Weight% / Δ | Avg px / Perf. | Hold / Status |
|---|---|---|---|---|---|---|---|
| 1 | ECOR1 CAPITAL, LLC | 22.97M +— (+0.0%) | 604.81M +212.5M (+54.2%) | 30.32% -0.173 pp | 27.44% +8.614 pp | USD10.13 +159.9% | 13 qtrs — |
| 2 | RUBRIC CAPITAL MANAGEMENT LP | 5.75M +1.0M (+22.1%) | 151.40M +70.9M (+88.2%) | 7.59% +1.336 pp | 1.81% +0.903 pp | USD12.14 +116.9% | 13 qtrs — |
| 3 | BLACKROCK, INC. | 4.60M +606.0K (+15.2%) | 121.00M +52.9M (+77.6%) | 6.07% +0.770 pp | 0.00% +0.001 pp | USD14.56 +80.8% | 6 qtrs — |
| 4 | BVF INC/IL | 3.94M +— (+0.0%) | 103.70M +36.4M (+54.2%) | 5.20% -0.030 pp | 3.49% +0.764 pp | USD7.86 +235.0% | 13 qtrs — |
| 5 | PERCEPTIVE ADVISORS LLC | 3.26M +1.2M (+56.0%) | 85.88M +50.2M (+140.5%) | 4.31% +1.530 pp | 1.53% +0.500 pp | USD17.31 +52.1% | 13 qtrs — |
| 6 | MORGAN STANLEY | 2.59M -1.4M (-34.9%) | 68.28M +219.1K (+0.3%) | 3.42% -1.867 pp | 0.00% +0.000 pp | USD8.98 +193.2% | 13 qtrs — |
| 7 | VANGUARD GROUP INC | 2.33M +174.3K (+8.1%) | 61.32M +24.5M (+66.6%) | 3.07% +0.214 pp | 0.00% +0.000 pp | USD10.72 +145.6% | 13 qtrs — |
| 8 | BNP PARIBAS ASSET MANAGEMENT HOLDING S.A. | 1.82M +1.8M (+100.0%) | 47.98M +48.0M (+100.0%) | 2.40% +2.405 pp | 0.06% +0.055 pp | USD26.33 +0.0% | 13 qtrs — |
| 9 | SIREN, L.L.C. | 1.68M +1.7M (+100.0%) | 44.24M +44.2M (+100.0%) | 2.22% +2.218 pp | 1.32% +1.320 pp | USD26.33 +0.0% | 1 qtrs NEW |
| 10 | DEUTSCHE BANK AG\ | 1.60M +50.9K (+3.3%) | 42.02M +15.6M (+59.2%) | 2.11% +0.056 pp | 0.01% +0.005 pp | USD9.78 +169.2% | 13 qtrs — |
| 11 | DIMENSIONAL FUND ADVISORS LP | 1.16M -31.6K (-2.7%) | 30.52M +10.2M (+50.1%) | 1.53% -0.051 pp | 0.01% +0.002 pp | USD9.93 +165.2% | 12 qtrs — |
| 12 | NEXTECH INVEST, LTD. | 1.11M +— (+0.0%) | 29.33M +10.3M (+54.2%) | 1.47% -0.008 pp | 2.84% -0.061 pp | USD11.91 +121.1% | 4 qtrs — |
| 13 | STATE STREET CORP | 1.04M -43.5K (-4.0%) | 27.32M +8.9M (+47.9%) | 1.37% -0.066 pp | 0.00% +0.000 pp | USD8.91 +195.5% | 13 qtrs — |
| 14 | CAPRICORN FUND MANAGERS LTD | 1.02M +1.0M (+100.0%) | 26.93M +26.9M (+100.0%) | 1.35% +1.350 pp | 6.49% +6.491 pp | USD26.33 +0.0% | 1 qtrs NEW |
| 15 | VESTAL POINT CAPITAL, LP | 865.0K -900.0K (-51.0%) | 22.78M -7.4M (-24.5%) | 1.14% -1.201 pp | 0.77% -0.587 pp | USD13.72 +91.9% | 7 qtrs — |
| 16 | ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 700.0K +386.2K (+123.1%) | 18.43M +13.1M (+243.9%) | 0.92% +0.507 pp | 0.01% +0.007 pp | USD22.18 +18.7% | 2 qtrs — |
| 17 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 663.5K +99.5K (+17.7%) | 17.47M +7.8M (+81.4%) | 0.88% +0.127 pp | 0.03% +0.011 pp | USD15.22 +73.0% | 3 qtrs — |
| 18 | NUVEEN, LLC | 648.3K +82.9K (+14.7%) | 17.07M +7.4M (+76.8%) | 0.86% +0.105 pp | 0.00% +0.002 pp | USD14.14 +86.2% | 4 qtrs — |
| 19 | GEODE CAPITAL MANAGEMENT, LLC | 648.0K -30.7K (-4.5%) | 17.06M +5.5M (+47.2%) | 0.86% -0.046 pp | 0.00% +0.000 pp | USD8.76 +200.6% | 12 qtrs — |
| 20 | ASSENAGON ASSET MANAGEMENT S.A. | 647.4K -679.4K (-51.2%) | 17.05M -5.6M (-24.8%) | 0.85% -0.907 pp | 0.02% -0.008 pp | USD15.77 +67.0% | 8 qtrs — |
| 21 | FMR LLC | 560.1K +556.6K (+15,838.7%) | 14.75M +14.7M (+24,471.9%) | 0.74% +0.735 pp | 0.00% +0.001 pp | USD26.25 +0.3% | 11 qtrs — |
| 22 | PROSIGHT MANAGEMENT, LP | 530.4K -219.2K (-29.2%) | 13.97M +1.2M (+9.1%) | 0.70% -0.295 pp | 2.89% -0.100 pp | USD10.29 +155.9% | 10 qtrs — |
| 23 | REDMILE GROUP, LLC | 491.7K -3.2M (-86.7%) | 12.95M -50.3M (-79.5%) | 0.65% -4.270 pp | 0.95% -5.205 pp | USD7.92 +232.4% | 13 qtrs — |
| 24 | QUBE RESEARCH & TECHNOLOGIES LTD | 474.3K +219.3K (+86.0%) | 12.49M +8.1M (+186.7%) | 0.63% +0.288 pp | 0.01% +0.008 pp | USD20.69 +27.3% | 12 qtrs — |
| 25 | ALGERT GLOBAL LLC | 423.6K +215.7K (+103.7%) | 11.16M +7.6M (+214.1%) | 0.56% +0.283 pp | 0.17% +0.115 pp | USD20.53 +28.3% | 3 qtrs — |
| 26 | GOLDMAN SACHS GROUP INC | 420.2K -23.3K (-5.3%) | 11.06M +3.5M (+46.1%) | 0.55% -0.034 pp | 0.00% +0.000 pp | USD11.64 +126.2% | 13 qtrs — |
| 27 | MILLENNIUM MANAGEMENT LLC | 381.6K -723.2K (-65.5%) | 10.05M -8.8M (-46.8%) | 0.50% -0.963 pp | 0.00% -0.004 pp | USD16.54 +59.2% | 4 qtrs — |
| 28 | UBS ASSET MANAGEMENT AMERICAS INC | 320.3K -1.4M (-81.3%) | 8.43M -20.8M (-71.1%) | 0.42% -1.848 pp | 0.00% -0.005 pp | USD10.75 +144.9% | 12 qtrs — |
| 29 | NORTHERN TRUST CORP | 308.0K -40.3K (-11.6%) | 8.11M +2.2M (+36.3%) | 0.41% -0.056 pp | 0.00% +0.000 pp | USD9.06 +190.6% | 13 qtrs — |
| 30 | SCHONFELD STRATEGIC ADVISORS LLC | 288.6K +180.8K (+167.7%) | 7.60M +5.8M (+312.7%) | 0.38% +0.238 pp | 0.03% +0.023 pp | USD22.87 +15.1% | 5 qtrs — |
| 31 | UBS GROUP AG | 278.9K +227.0K (+437.9%) | 7.34M +6.5M (+729.2%) | 0.37% +0.299 pp | 0.00% +0.001 pp | USD23.46 +12.2% | 13 qtrs — |
| 32 | INVESCO LTD. | 257.6K +163.9K (+175.0%) | 6.78M +5.2M (+324.0%) | 0.34% +0.216 pp | 0.00% +0.001 pp | USD21.00 +25.4% | 13 qtrs — |
| 33 | CITADEL ADVISORS LLC | 255.4K +48.5K (+23.4%) | 6.72M +3.2M (+90.3%) | 0.34% +0.062 pp | 0.00% +0.001 pp | USD14.99 +75.7% | 13 qtrs — |
| 34 | PICTON MAHONEY ASSET MANAGEMENT | 244.8K +38.5K (+18.6%) | 6.45M +2.9M (+82.9%) | 0.32% +0.049 pp | 0.05% +0.018 pp | USD10.98 +139.8% | 13 qtrs — |
| 35 | DIADEMA PARTNERS LP | 240.6K +44.1K (+22.4%) | 6.33M +3.0M (+88.8%) | 0.32% +0.057 pp | 1.09% +0.233 pp | USD14.92 +76.5% | 4 qtrs — |
| 36 | HILLSDALE INVESTMENT MANAGEMENT INC. | 237.9K +21.5K (+9.9%) | 6.26M +2.6M (+69.5%) | 0.31% +0.027 pp | 0.17% +0.061 pp | USD15.74 +67.3% | 5 qtrs — |
| 37 | GRANAHAN INVESTMENT MANAGEMENT, LLC | 224.4K -120.9K (-35.0%) | 5.91M +10.4K (+0.2%) | 0.30% -0.162 pp | 0.25% +0.012 pp | USD7.79 +238.0% | 13 qtrs — |
| 38 | SUMMITTX CAPITAL, L.P. | 224.3K +224.3K (+100.0%) | 5.90M +5.9M (+100.0%) | 0.30% +0.296 pp | 0.18% +0.178 pp | USD26.33 +0.0% | 1 qtrs NEW |
| 39 | D. E. SHAW & CO., INC. | 223.8K +96.9K (+76.3%) | 5.89M +3.7M (+171.8%) | 0.30% +0.127 pp | 0.00% +0.002 pp | USD18.31 +43.8% | 13 qtrs — |
| 40 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 220.9K +27.5K (+14.2%) | 5.82M +2.5M (+76.1%) | 0.29% +0.035 pp | 0.00% +0.000 pp | USD13.56 +94.2% | 11 qtrs — |
| 41 | RENAISSANCE TECHNOLOGIES LLC | 220.9K -210.8K (-48.8%) | 5.82M -1.6M (-21.1%) | 0.29% -0.282 pp | 0.01% -0.001 pp | USD11.57 +127.6% | 13 qtrs — |
| 42 | WELLS FARGO & COMPANY/MN | 208.3K +31.7K (+17.9%) | 5.48M +2.5M (+81.8%) | 0.27% +0.041 pp | 0.00% +0.000 pp | USD13.10 +101.0% | 13 qtrs — |
| 43 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 194.1K +39.9K (+25.9%) | 5.11M +2.5M (+94.0%) | 0.26% +0.052 pp | 0.00% +0.000 pp | USD17.07 +54.2% | 13 qtrs — |
| 44 | RAYMOND JAMES FINANCIAL INC | 187.7K +64.8K (+52.8%) | 4.94M +2.8M (+135.5%) | 0.25% +0.085 pp | 0.00% +0.001 pp | USD17.79 +48.0% | 5 qtrs — |
| 45 | SILVERCREST ASSET MANAGEMENT GROUP LLC | 181.8K -91.0K (-33.4%) | 4.79M +127.2K (+2.7%) | 0.24% -0.122 pp | 0.03% +0.002 pp | USD8.69 +203.0% | 11 qtrs — |
| 46 | WELLINGTON MANAGEMENT GROUP LLP | 181.7K +13.0K (+7.7%) | 4.78M +1.9M (+66.1%) | 0.24% +0.016 pp | 0.00% +0.000 pp | USD9.78 +169.2% | 11 qtrs — |
| 47 | FEDERATED HERMES, INC. | 152.7K -30.2K (-16.5%) | 4.02M +897.3K (+28.7%) | 0.20% -0.041 pp | 0.01% +0.001 pp | USD10.00 +163.3% | 9 qtrs — |
| 48 | KENNEDY CAPITAL MANAGEMENT LLC | 145.5K -906.0 (-0.6%) | 3.83M +1.3M (+53.2%) | 0.19% -0.002 pp | 0.08% +0.026 pp | USD6.79 +287.8% | 14 qtrs — |
| 49 | BANK OF NEW YORK MELLON CORP | 128.1K -9.4K (-6.8%) | 3.37M +1.0M (+43.6%) | 0.17% -0.014 pp | 0.00% +0.000 pp | USD9.99 +163.6% | 11 qtrs — |
| 50 | JUPITER ASSET MANAGEMENT LTD | 125.5K -225.2K (-64.2%) | 3.30M -2.7M (-44.8%) | 0.17% -0.300 pp | 0.03% -0.025 pp | USD6.73 +291.2% | 11 qtrs — |
| 51 | HRT FINANCIAL LP | 121.1K +52.6K (+76.8%) | 3.19M +2.0M (+172.6%) | 0.16% +0.069 pp | 0.01% +0.006 pp | USD20.15 +30.7% | 6 qtrs — |
| 52 | AMERIPRISE FINANCIAL INC | 113.1K +37.2K (+49.0%) | 2.98M +1.7M (+129.7%) | 0.15% +0.049 pp | 0.00% +0.000 pp | USD20.12 +30.9% | 2 qtrs — |
| 53 | CITIGROUP INC | 111.2K -6.6K (-5.6%) | 2.93M +916.0K (+45.5%) | 0.15% -0.010 pp | 0.00% +0.000 pp | USD11.89 +121.4% | 13 qtrs — |
| 54 | OPALEYE MANAGEMENT INC. | 108.9K +8.9K (+8.9%) | 2.87M +1.2M (+67.9%) | 0.14% +0.011 pp | 0.38% +0.137 pp | USD13.19 +99.6% | 4 qtrs — |
| 55 | PLATINUM INVESTMENT MANAGEMENT LTD | 105.2K -19.6K (-15.7%) | 2.77M +638.2K (+29.9%) | 0.14% -0.027 pp | 0.64% +0.502 pp | USD7.94 +231.6% | 13 qtrs — |
| 56 | TREXQUANT INVESTMENT LP | 101.3K +101.3K (+100.0%) | 2.67M +2.7M (+100.0%) | 0.13% +0.134 pp | 0.02% +0.024 pp | USD26.33 +0.0% | 5 qtrs — |
| 57 | SOLEUS CAPITAL MANAGEMENT, L.P. | 100.0K +100.0K (+100.0%) | 2.63M +2.6M (+100.0%) | 0.13% +0.132 pp | 0.10% +0.097 pp | USD26.33 +0.0% | 1 qtrs NEW |
| 58 | SUSQUEHANNA PORTFOLIO STRATEGIES, LLC | 99.8K +15.6K (+18.5%) | 2.63M +1.2M (+82.7%) | 0.13% +0.020 pp | 0.04% +0.018 pp | USD14.70 +79.1% | 3 qtrs — |
| 59 | SCHRODER INVESTMENT MANAGEMENT GROUP | 97.9K -63.6K (-39.4%) | 2.60M -184.0K (-6.6%) | 0.13% -0.085 pp | 0.00% 0.000 pp | USD14.64 +79.8% | 5 qtrs — |
| 60 | XTX TOPCO LTD | 93.5K +93.5K (+100.0%) | 2.46M +2.5M (+100.0%) | 0.12% +0.123 pp | 0.06% +0.065 pp | USD26.33 +0.0% | 7 qtrs — |
| 61 | AQR CAPITAL MANAGEMENT LLC | 91.1K -61.6K (-40.3%) | 2.40M -208.9K (-8.0%) | 0.12% -0.082 pp | 0.00% 0.000 pp | USD11.75 +124.1% | 11 qtrs — |
| 62 | BANK OF AMERICA CORP /DE/ | 89.5K +14.2K (+18.8%) | 2.36M +1.1M (+83.2%) | 0.12% +0.018 pp | 0.00% +0.000 pp | USD13.37 +96.9% | 13 qtrs — |
| 63 | KORNITZER CAPITAL MANAGEMENT INC /KS | 88.8K +88.8K (+100.0%) | 2.34M +2.3M (+100.0%) | 0.12% +0.117 pp | 0.05% +0.049 pp | USD26.33 +0.0% | 1 qtrs NEW |
| 64 | ACUTA CAPITAL PARTNERS, LLC | 80.1K +— (+0.0%) | 2.11M +741.3K (+54.2%) | 0.11% -0.001 pp | 1.43% +0.018 pp | USD14.22 +85.2% | 5 qtrs — |
| 65 | BARCLAYS PLC | 80.0K -74.4K (-48.2%) | 2.11M +168.0K (+8.7%) | 0.11% -0.099 pp | 0.00% +0.000 pp | USD13.66 +92.8% | 9 qtrs — |
| 66 | PANAGORA ASSET MANAGEMENT INC | 78.3K -27.7K (-26.1%) | 2.06M +250.9K (+13.8%) | 0.10% -0.037 pp | 0.01% +0.000 pp | USD15.65 +68.2% | 6 qtrs — |
| 67 | NEOS INVESTMENT MANAGEMENT LLC | 77.1K +13.5K (+21.1%) | 2.03M +943.1K (+86.7%) | 0.10% +0.017 pp | 0.01% +0.004 pp | USD15.37 +71.3% | 4 qtrs — |
| 68 | TEMA ETFS LLC | 76.0K +12.3K (+19.3%) | 2.00M +913.1K (+84.0%) | 0.10% +0.016 pp | 0.16% +0.065 pp | USD15.21 +73.1% | 4 qtrs — |
| 69 | STIFEL FINANCIAL CORP | 75.8K +3.3K (+4.6%) | 2.00M +758.2K (+61.2%) | 0.10% +0.004 pp | 0.00% +0.001 pp | USD9.64 +173.1% | 13 qtrs — |
| 70 | STATE OF WISCONSIN INVESTMENT BOARD | 75.6K +19.3K (+34.3%) | 1.99M +1.0M (+107.0%) | 0.10% +0.025 pp | 0.00% +0.002 pp | USD17.08 +54.2% | 12 qtrs — |
| 71 | RHUMBLINE ADVISERS | 75.5K -10.4K (-12.1%) | 1.99M +520.7K (+35.5%) | 0.10% -0.014 pp | 0.00% +0.000 pp | USD9.78 +169.2% | 11 qtrs — |
| 72 | MAN GROUP PLC | 75.3K -83.3K (-52.5%) | 1.98M -726.0K (-26.8%) | 0.10% -0.111 pp | 0.00% -0.001 pp | USD16.02 +64.4% | 4 qtrs — |
| 73 | CREDIT AGRICOLE S A | 75.0K +75.0K (+100.0%) | 1.97M +2.0M (+100.0%) | 0.10% +0.099 pp | 0.00% +0.005 pp | USD26.33 +0.0% | 1 qtrs NEW |
| 74 | PICTET ASSET MANAGEMENT HOLDING SA | 73.6K +73.6K (+100.0%) | 1.97M +2.0M (+100.0%) | 0.10% +0.097 pp | 0.00% +0.002 pp | USD26.33 +0.0% | 1 qtrs NEW |
| 75 | SWISS NATIONAL BANK | 74.2K +1.1K (+1.5%) | 1.95M +705.1K (+56.5%) | 0.10% +0.001 pp | 0.00% +0.000 pp | USD9.13 +188.4% | 12 qtrs — |
| 76 | JANE STREET GROUP, LLC | 70.4K -74.8K (-51.5%) | 1.85M -625.3K (-25.2%) | 0.09% -0.100 pp | 0.00% 0.000 pp | USD16.61 +58.5% | 9 qtrs — |
| 77 | FISHER ASSET MANAGEMENT, LLC | 68.2K -3.8K (-5.2%) | 1.80M +566.3K (+46.1%) | 0.09% -0.006 pp | 0.00% +0.000 pp | USD8.99 +192.9% | 7 qtrs — |
| 78 | DLD ASSET MANAGEMENT, LP | 62.0K +9.1K (+17.2%) | 1.63M +728.1K (+80.5%) | 0.08% +0.012 pp | 0.12% +0.073 pp | USD18.44 +42.8% | 2 qtrs — |
| 79 | PENSERRA CAPITAL MANAGEMENT LLC | 60.1K +60.1K (+100.0%) | 1.58M +1.6M (+100.0%) | 0.08% +0.079 pp | 0.02% +0.019 pp | USD26.33 +0.0% | 1 qtrs NEW |
| 80 | FRANKLIN RESOURCES INC | 59.0K +25.2K (+74.4%) | 1.55M +975.5K (+168.9%) | 0.08% +0.033 pp | 0.00% +0.000 pp | USD21.03 +25.2% | 4 qtrs — |
| 81 | AMERICAN CENTURY COMPANIES INC | 58.8K +7.8K (+15.3%) | 1.55M +677.7K (+77.8%) | 0.08% +0.010 pp | 0.00% +0.000 pp | USD17.02 +54.7% | 5 qtrs — |
| 82 | RUSSELL INVESTMENTS GROUP, LTD. | 58.4K +902.0 (+1.6%) | 1.54M +555.1K (+56.6%) | 0.08% +0.001 pp | 0.00% +0.001 pp | USD14.89 +76.8% | 13 qtrs — |
| 83 | ROYAL BANK OF CANADA | 55.1K -2.9K (-5.0%) | 1.45M +461.0K (+46.6%) | 0.07% -0.004 pp | 0.00% +0.000 pp | USD9.00 +192.6% | 13 qtrs — |
| 84 | ALLIANCEBERNSTEIN L.P. | 50.0K +— (+0.0%) | 1.32M +462.8K (+54.2%) | 0.07% 0.000 pp | 0.00% +0.000 pp | USD8.48 +210.5% | 11 qtrs — |
| 85 | DANA INVESTMENT ADVISORS, INC. | 48.3K +48.3K (+100.0%) | 1.27M +1.3M (+100.0%) | 0.06% +0.064 pp | 0.04% +0.037 pp | USD26.33 +0.0% | 1 qtrs NEW |
| 86 | SIMPLEX TRADING, LLC | 48.0K +19.3K (+67.0%) | 1.26M +773.9K (+157.6%) | 0.06% +0.025 pp | 0.00% +0.001 pp | USD20.06 +31.3% | 13 qtrs — |
| 87 | MACKENZIE FINANCIAL CORP | 45.5K -10.9K (-19.4%) | 1.20M +241.2K (+25.1%) | 0.06% -0.015 pp | 0.00% +0.000 pp | USD15.36 +71.4% | 3 qtrs — |
| 88 | NORTH GROWTH MANAGEMENT LTD. | 45.0K -37.0K (-45.1%) | 1.18M -226.0K (-16.0%) | 0.06% -0.050 pp | 0.19% -0.060 pp | USD8.30 +217.2% | 13 qtrs — |
| 89 | O'SHAUGHNESSY ASSET MANAGEMENT, LLC | 43.1K +1.3K (+3.1%) | 1.13M +420.2K (+58.9%) | 0.06% +0.001 pp | 0.01% +0.002 pp | USD10.13 +159.9% | 11 qtrs — |
| 90 | VICTORY CAPITAL MANAGEMENT INC | 42.9K +8.4K (+24.3%) | 1.13M +540.3K (+91.7%) | 0.06% +0.011 pp | 0.00% +0.000 pp | USD12.90 +104.1% | 8 qtrs — |
| 91 | ENVESTNET ASSET MANAGEMENT INC | 40.8K +26.2K (+180.0%) | 1.07M +825.7K (+331.7%) | 0.05% +0.035 pp | 0.00% +0.000 pp | USD20.00 +31.7% | 13 qtrs — |
| 92 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 37.8K +2.5K (+7.2%) | 994.2K +392.5K (+65.2%) | 0.05% +0.003 pp | 0.00% +0.000 pp | USD10.20 +158.1% | 12 qtrs — |
| 93 | JPMORGAN CHASE & CO | 35.0K +1.1K (+3.3%) | 921.8K +343.0K (+59.3%) | 0.05% +0.001 pp | 0.00% +0.000 pp | USD13.00 +102.5% | 12 qtrs — |
| 94 | TANG CAPITAL MANAGEMENT LLC | 34.6K -1.1M (-96.9%) | 911.8K -17.9M (-95.1%) | 0.05% -1.414 pp | 0.05% -0.678 pp | USD8.61 +205.8% | 13 qtrs — |
| 95 | CAMPBELL & CO INVESTMENT ADVISER LLC | 33.6K +1.1K (+3.4%) | 884.4K +329.4K (+59.4%) | 0.04% +0.001 pp | 0.04% +0.001 pp | USD15.36 +71.4% | 3 qtrs — |
| 96 | UNIVERSAL- BETEILIGUNGS- UND SERVICEGESELLSCHAFT MBH | 32.8K +2.4K (+7.8%) | 864.0K +344.2K (+66.2%) | 0.04% +0.003 pp | 0.00% +0.001 pp | USD15.78 +66.9% | 3 qtrs — |
| 97 | LEGAL & GENERAL GROUP PLC | 32.1K +3.8K (+13.3%) | 846.5K +361.9K (+74.7%) | 0.04% +0.005 pp | 0.00% +0.000 pp | USD12.09 +117.8% | 12 qtrs — |
Ownership breakdown by holder
ETF Ownership
Top ETFs holding this stock
Held by 89 ETFs in our universe
| # | ETF | Weight | Est. AUM exposure | TER |
|---|---|---|---|---|
| 1 | Virtus Biotech ETF BBP | 1.46% | 1.43M | 0.34% |
| 2 | Tema Oncology ETF CANC | 1.42% | 2.02M | 0.75% |
| 3 | Franklin Small Cap Enhanced ETF FSML | 1.02% | 1.52M | 0.45% |
| 4 | iShares MSCI USA Small-Cap Min Vol Factor ETF SMMV | 0.15% | 429.1K | 0.20% |
| 5 | Federated Hermes MDT Small Cap Core ETF FSCC | 0.14% | 234.4K | 0.51% |
| 6 | iShares Biotechnology ETF IBB | 0.14% | 13.20M | 0.44% |
| 7 | Invesco Russell 2000 Dynamic Multifactor ETF OMFS | 0.13% | 382.6K | 0.39% |
| 8 | iShares Healthcare Innovation UCITS ETF HEAL.L | 0.13% | 1.53M | 0.40% |
| 9 | Invesco NASDAQ Biotech UCITS ETF SBIO.L | 0.13% | 601.4K | 0.40% |
| 10 | Invesco Nasdaq Biotechnology ETF IBBQ | 0.13% | 97.1K | 0.19% |
Insider Activity
Insider Activity — Latest Quarter
Ratio by transactions
0.00
Bearish
Buys
9
Sells
0
Shares acquired
733.0K
Shares disposed
—
Cash buys
—
Cash sales
—
Net activity
+733,000
Insider buys vs sells (history)
From
To
Recent insider transactions
From
To
| Date | Person | Role | Transaction | A/D | Security | Shares | Price | Value | Owned after | D/I | Filing |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026-04-09 | Schayowitz Adam | Officer | A-Award | A | Performance Stock Unit | 76,000 | 0.00 | — | 76,000 | D | ↗ |
| 2026-04-09 | Platshon Scott | Officer | A-Award | A | Performance Stock Unit | 76,000 | 0.00 | — | 76,000 | D | ↗ |
| 2026-04-06 | Stafford Kristin | Officer | A-Award | A | Restricted Stock Unit | 50,000 | 0.00 | — | 50,000 | D | ↗ |
| 2026-04-01 | Stafford Kristin | Officer | — | — | No securities are beneficially owned | 0 | 0.00 | — | 0 | D | ↗ |
| 2026-02-01 | Mekan Sabeen | Officer | — | — | Stock Option (Right to Buy) | 29,000 | 23.16 | 671.6K | 0 | D | ↗ |
| 2026-01-12 | Smith Jeffrey T L | Officer | M-Exempt | D | Restricted Stock Unit | 17,666 | 0.00 | — | 35,334 | D | ↗ |
| 2026-01-12 | Neu Kelvin | Director | A-Award | A | Restricted Stock Unit | 7,700 | 0.00 | — | 7,700 | D | ↗ |
| 2026-01-12 | Moore Paul Andrew | Officer | A-Award | A | Performance Stock Unit | 66,000 | 0.00 | — | 66,000 | D | ↗ |
| 2026-01-12 | Mahony Susan | Director | A-Award | A | Stock Option (Right to Buy) | 11,500 | 23.16 | 266.3K | 11,500 | D | ↗ |
| 2026-01-12 | Landry Robert E | Director | A-Award | A | Stock Option (Right to Buy) | 11,500 | 23.16 | 266.3K | 11,500 | D | ↗ |
| 2026-01-12 | Hollywood Mark | Officer | M-Exempt | A | Common Stock | 17,666 | 0.00 | — | 139,033 | D | ↗ |
| 2026-01-12 | Galbraith Kenneth | Director / Officer | M-Exempt | D | Restricted Stock Unit | 64,000 | 0.00 | — | 128,000 | D | ↗ |
| 2026-01-12 | Ciongoli Gregory Austin | Director | A-Award | A | Restricted Stock Unit | 7,700 | 0.00 | — | 7,700 | D | ↗ |
| 2026-01-12 | Cherry Brian N | Director | A-Award | A | Stock Option (Right to Buy) | 23,000 | 23.16 | 532.7K | 23,000 | D | ↗ |
| 2026-01-12 | Cesano Alessandra | Director | A-Award | A | Stock Option (Right to Buy) | 11,500 | 23.16 | 266.3K | 11,500 | D | ↗ |
| 2026-01-12 | Campoy Carlos | Director | A-Award | A | Stock Option (Right to Buy) | 11,500 | 23.16 | 266.3K | 11,500 | D | ↗ |
| 2026-01-09 | Hollywood Mark | Officer | — | — | Stock Option (Right to Buy) | 30,000 | 34.82 | 1.04M | 0 | D | ↗ |
| 2026-01-06 | PATTERSON LEONE D | Officer | A-Award | A | Common Stock | 459 | 10.55 | 4.8K | 459 | D | ↗ |
| 2026-01-05 | Smith Jeffrey T L | Officer | M-Exempt | D | Restricted Stock Unit | 20,000 | 0.00 | — | 20,000 | D | ↗ |
| 2026-01-05 | Moore Paul Andrew | Officer | M-Exempt | D | Restricted Stock Unit | 17,168 | 0.00 | — | 0 | D | ↗ |
| 2026-01-05 | Galbraith Kenneth | Director / Officer | M-Exempt | D | Restricted Stock Unit | 66,666 | 0.00 | — | 66,668 | D | ↗ |
| 2025-12-22 | Galbraith Kenneth | Director / Officer | M-Exempt | A | Common Stock | 100,000 | 0.00 | — | 180,803 | D | ↗ |
| 2025-08-12 | Ciongoli Gregory Austin | Director | A-Award | A | Common Stock | 415,000 | 12.02 | 4.99M | 488,500 | D | ↗ |
| 2025-08-11 | Landry Robert E | Director | A-Award | A | Stock Option (Right to Buy) | 62,000 | 12.44 | 771.3K | 62,000 | D | ↗ |
| 2025-08-11 | Ciongoli Gregory Austin | Director | A-Award | A | Stock Option (Right to Buy) | 62,000 | 12.44 | 771.3K | 62,000 | D | ↗ |
| 2025-08-10 | Landry Robert E | Director | — | — | No securities are beneficially owned | 0 | 0.00 | — | 0 | D | ↗ |
| 2025-08-10 | Ciongoli Gregory Austin | Director | — | — | Common Stock | 0 | 0.00 | — | 73,500 | D | ↗ |
| 2025-06-26 | EcoR1 Capital, LLC | Director / 10% Owner | X-InTheMoney | A | Common Stock | 5,086,480 | 0.00 | 508.65 | 22,970,388 | I | ↗ |
| 2025-05-19 | EcoR1 Capital, LLC | Director / 10% Owner | P-Purchase | A | Common Stock | 5,919 | 11.78 | 69.7K | 17,883,908 | I | ↗ |
| 2025-05-15 | EcoR1 Capital, LLC | Director / 10% Owner | P-Purchase | A | Common Stock | 49,502 | 11.43 | 565.8K | 17,877,989 | I | ↗ |
| 2025-04-17 | EcoR1 Capital, LLC | Director / 10% Owner | P-Purchase | A | Common Stock | 54,760 | 11.52 | 630.8K | 17,828,487 | I | ↗ |
| 2025-04-16 | EcoR1 Capital, LLC | Director / 10% Owner | P-Purchase | A | Common Stock | 73,953 | 11.16 | 825.6K | 17,773,727 | I | ↗ |
| 2025-04-04 | EcoR1 Capital, LLC | Director / 10% Owner | P-Purchase | A | Common Stock | 196,438 | 11.17 | 2.19M | 17,699,774 | I | ↗ |
| 2025-04-03 | EcoR1 Capital, LLC | Director / 10% Owner | P-Purchase | A | Common Stock | 120,770 | 11.84 | 1.43M | 17,503,336 | I | ↗ |
| 2025-04-02 | EcoR1 Capital, LLC | Director / 10% Owner | P-Purchase | A | Common Stock | 74,360 | 11.85 | 881.0K | 17,382,566 | I | ↗ |
| 2025-04-01 | EcoR1 Capital, LLC | Director / 10% Owner | P-Purchase | A | Common Stock | 48,658 | 11.60 | 564.6K | 17,308,206 | I | ↗ |
| 2025-03-31 | EcoR1 Capital, LLC | Director / 10% Owner | P-Purchase | A | Common Stock | 4,397 | 11.75 | 51.7K | 17,259,548 | I | ↗ |
| 2025-03-26 | EcoR1 Capital, LLC | Director / 10% Owner | P-Purchase | A | Common Stock | 43,848 | 12.24 | 536.9K | 17,255,151 | I | ↗ |
| 2025-03-25 | EcoR1 Capital, LLC | Director / 10% Owner | P-Purchase | A | Common Stock | 53,501 | 12.91 | 690.5K | 17,211,303 | I | ↗ |
| 2025-03-24 | EcoR1 Capital, LLC | Director / 10% Owner | P-Purchase | A | Common Stock | 22,689 | 13.08 | 296.8K | 17,157,802 | I | ↗ |
| 2025-03-21 | EcoR1 Capital, LLC | Director / 10% Owner | P-Purchase | A | Common Stock | 31,033 | 12.78 | 396.5K | 17,135,113 | I | ↗ |
| 2025-03-20 | EcoR1 Capital, LLC | Director / 10% Owner | P-Purchase | A | Common Stock | 73,476 | 12.93 | 949.9K | 17,104,080 | I | ↗ |
| 2025-03-19 | EcoR1 Capital, LLC | Director / 10% Owner | P-Purchase | A | Common Stock | 58,306 | 12.64 | 737.2K | 17,030,604 | I | ↗ |
| 2025-03-18 | EcoR1 Capital, LLC | Director / 10% Owner | P-Purchase | A | Common Stock | 113,880 | 12.65 | 1.44M | 16,972,298 | I | ↗ |
| 2025-03-17 | EcoR1 Capital, LLC | Director / 10% Owner | P-Purchase | A | Common Stock | 56,277 | 12.23 | 688.5K | 16,858,418 | I | ↗ |
| 2025-03-13 | EcoR1 Capital, LLC | Director / 10% Owner | P-Purchase | A | Common Stock | 468,356 | 12.48 | 5.85M | 16,802,141 | I | ↗ |
| 2025-03-12 | EcoR1 Capital, LLC | Director / 10% Owner | P-Purchase | A | Common Stock | 292,934 | 12.25 | 3.59M | 16,333,785 | I | ↗ |
| 2025-03-11 | EcoR1 Capital, LLC | Director / 10% Owner | P-Purchase | A | Common Stock | 320,690 | 11.49 | 3.69M | 16,040,851 | I | ↗ |
| 2025-02-17 | NODELMAN OLEG | Director / 10% Owner | — | — | Common Stock | 0 | 0.00 | — | 15,720,161 | I | ↗ |
| 2025-01-17 | EcoR1 Capital, LLC | Director / 10% Owner | P-Purchase | A | Common Stock | 19,748 | 13.87 | 274.0K | 15,720,161 | I | ↗ |
| 2025-01-16 | EcoR1 Capital, LLC | Director / 10% Owner | P-Purchase | A | Common Stock | 121,681 | 13.89 | 1.69M | 15,700,413 | I | ↗ |
| 2025-01-15 | EcoR1 Capital, LLC | Director / 10% Owner | P-Purchase | A | Common Stock | 39,029 | 14.01 | 546.7K | 15,578,732 | I | ↗ |
| 2025-01-14 | EcoR1 Capital, LLC | Director / 10% Owner | P-Purchase | A | Common Stock | 54,500 | 13.56 | 739.3K | 15,539,703 | I | ↗ |
| 2025-01-13 | EcoR1 Capital, LLC | Director / 10% Owner | P-Purchase | A | Common Stock | 74,125 | 13.39 | 992.9K | 15,485,203 | I | ↗ |
| 2025-01-10 | Smith Jeffrey T L | Officer | A-Award | A | Stock Option (Right to Buy) | 79,000 | 13.22 | 1.04M | 79,000 | D | ↗ |
| 2025-01-10 | PATTERSON LEONE D | Officer | A-Award | A | Restricted Stock Unit | 53,000 | 0.00 | — | 53,000 | D | ↗ |
| 2025-01-10 | Moore Paul Andrew | Officer | A-Award | A | Stock Option (Right to Buy) | 79,000 | 13.22 | 1.04M | 79,000 | D | ↗ |
| 2025-01-10 | Galbraith Kenneth | Director / Officer | A-Award | A | Restricted Stock Unit | 192,000 | 0.00 | — | 192,000 | D | ↗ |
| 2025-01-10 | EcoR1 Capital, LLC | Director / 10% Owner | P-Purchase | A | Common Stock | 204,098 | 13.13 | 2.68M | 15,411,078 | I | ↗ |
| 2025-01-08 | EcoR1 Capital, LLC | Director / 10% Owner | P-Purchase | A | Common Stock | 21,021 | 14.07 | 295.8K | 15,206,980 | I | ↗ |
| 2025-01-06 | Smith Jeffrey T L | Officer | M-Exempt | D | Restricted Stock Unit | 20,000 | 0.00 | — | 40,000 | D | ↗ |
| 2025-01-06 | Moore Paul Andrew | Officer | S-Sale | D | Common Stock | 9,792 | 14.92 | 146.1K | 14,741 | D | ↗ |
| 2025-01-06 | Galbraith Kenneth | Director / Officer | S-Sale | D | Common Stock | 23,885 | 14.92 | 356.5K | 47,543 | D | ↗ |
| 2025-01-02 | EcoR1 Capital, LLC | Director / 10% Owner | P-Purchase | A | Common Stock | 157,880 | 14.78 | 2.33M | 15,185,959 | I | ↗ |
| 2024-12-31 | EcoR1 Capital, LLC | Director / 10% Owner | P-Purchase | A | Common Stock | 146,501 | 14.57 | 2.13M | 15,028,079 | I | ↗ |
| 2024-12-30 | EcoR1 Capital, LLC | Director / 10% Owner | P-Purchase | A | Common Stock | 58,988 | 14.47 | 853.3K | 14,881,578 | I | ↗ |
| 2024-12-27 | EcoR1 Capital, LLC | Director / 10% Owner | P-Purchase | A | Common Stock | 101,659 | 14.49 | 1.47M | 14,822,590 | I | ↗ |
| 2024-12-26 | EcoR1 Capital, LLC | Director / 10% Owner | P-Purchase | A | Common Stock | 16,692 | 14.38 | 240.0K | 14,720,931 | I | ↗ |
| 2024-12-24 | EcoR1 Capital, LLC | Director / 10% Owner | P-Purchase | A | Common Stock | 11,958 | 14.12 | 168.9K | 14,704,239 | I | ↗ |
| 2024-12-23 | EcoR1 Capital, LLC | Director / 10% Owner | P-Purchase | A | Common Stock | 251,502 | 14.25 | 3.58M | 14,692,281 | I | ↗ |
| 2024-12-20 | EcoR1 Capital, LLC | Director / 10% Owner | P-Purchase | A | Common Stock | 704,488 | 14.08 | 9.92M | 14,440,779 | I | ↗ |
| 2024-12-19 | EcoR1 Capital, LLC | Director / 10% Owner | P-Purchase | A | Common Stock | 298,818 | 13.53 | 4.04M | 13,736,291 | I | ↗ |
| 2024-12-10 | Neu Kelvin | Director | A-Award | A | Stock Option (Right to Buy) | 31,000 | 13.06 | 404.9K | 31,000 | D | ↗ |
| 2024-12-10 | Miller Derek John Michael | Director | A-Award | A | Stock Option (Right to Buy) | 31,000 | 13.06 | 404.9K | 31,000 | D | ↗ |
| 2024-12-10 | Mahony Susan | Director | A-Award | A | Stock Option (Right to Buy) | 31,000 | 13.06 | 404.9K | 31,000 | D | ↗ |
| 2024-12-10 | Gallagher Neil | Director | A-Award | A | Stock Option (Right to Buy) | 31,000 | 13.06 | 404.9K | 31,000 | D | ↗ |
| 2024-12-10 | Davidson Nancy | Director | A-Award | A | Stock Option (Right to Buy) | 31,000 | 13.06 | 404.9K | 31,000 | D | ↗ |
| 2024-12-10 | Cox Troy | Director | A-Award | A | Stock Option (Right to Buy) | 31,000 | 13.06 | 404.9K | 31,000 | D | ↗ |
| 2024-12-10 | Cesano Alessandra | Director | A-Award | A | Stock Option (Right to Buy) | 31,000 | 13.06 | 404.9K | 31,000 | D | ↗ |
| 2024-12-10 | Campoy Carlos | Director | A-Award | A | Stock Option (Right to Buy) | 31,000 | 13.06 | 404.9K | 31,000 | D | ↗ |
| 2024-09-01 | PATTERSON LEONE D | Officer | A-Award | A | Stock Option (Right to Buy) | 360,000 | 11.73 | 4.22M | 360,000 | — | ↗ |
| 2024-04-02 | Gallagher Neil | Director | A-Award | A | Stock Option (Right to Buy) | 74,000 | 9.23 | 683.0K | 74,000 | — | ↗ |
| 2024-02-22 | Platshon Scott | Director | — | — | — | 0 | 0.00 | — | 0 | — | ↗ |
| 2024-02-08 | Cesano Alessandra | Director | A-Award | A | Stock Option (Right to Buy) | 74,000 | 11.47 | 848.8K | 74,000 | — | ↗ |
| 2024-01-08 | Moore Paul Andrew | Officer | S-Sale | D | Common Stock | 2,339 | 11.22 | 26.2K | 7,367 | — | ↗ |
| 2024-01-08 | Galbraith Kenneth | Director / Officer | S-Sale | D | Common Stock | 5,706 | 11.22 | 64.0K | 23,762 | — | ↗ |
| 2024-01-08 | Astle Christopher | Officer | S-Sale | D | Common Stock | 1,431 | 11.22 | 16.0K | 6,503 | — | ↗ |
| 2024-01-05 | Smith Jeffrey T L | Officer | A-Award | A | Stock Option (Right to Buy) | 90,000 | 10.56 | 950.4K | 90,000 | — | ↗ |
| 2024-01-05 | Moore Paul Andrew | Officer | S-Sale | D | Common Stock | 7,460 | 10.65 | 79.5K | 9,706 | — | ↗ |
| 2024-01-05 | Galbraith Kenneth | Director / Officer | M-Exempt | A | Common Stock | 47,666 | 0.00 | — | 47,666 | — | ↗ |
| 2024-01-05 | Astle Christopher | Officer | S-Sale | D | Common Stock | 4,563 | 10.65 | 48.6K | 7,934 | — | ↗ |
| 2024-01-03 | Smith Jeffrey T L | Officer | — | D | Stock Option (Right to Buy) | 188,000 | 8.00 | 1.50M | 0 | — | ↗ |
| 2023-12-26 | NODELMAN OLEG | Director / 10% Owner | — | — | Pre-Funded Warrants | 5,086,521 | 0.00 | 508.65 | 0 | I | ↗ |
| 2023-12-26 | EcoR1 Capital, LLC | 10% Owner | P-Purchase | A | Pre-Funded Warrants | 5,086,521 | 0.00 | 508.65 | 5,086,521 | — | ↗ |
| 2023-12-11 | Astle Christopher | Officer | M-Exempt | D | Restricted Stock Unit | 1,550 | 0.00 | — | 0 | — | ↗ |
| 2023-12-07 | RENTON HOLLINGS | Director | A-Award | A | Stock Option (Right to Buy) | 37,000 | 9.55 | 353.4K | 37,000 | — | ↗ |
| 2023-12-07 | Neu Kelvin | Director | A-Award | A | Stock Option (Right to Buy) | 37,000 | 9.55 | 353.4K | 37,000 | — | ↗ |
| 2023-12-07 | Miller Derek John Michael | Director | A-Award | A | Stock Option (Right to Buy) | 37,000 | 9.55 | 353.4K | 37,000 | — | ↗ |
| 2023-12-07 | Mahony Susan | Director | A-Award | A | Stock Option (Right to Buy) | 37,000 | 9.55 | 353.4K | 37,000 | — | ↗ |
| 2023-12-07 | Hillan Kenneth J. | Director | A-Award | A | Stock Option (Right to Buy) | 37,000 | 9.55 | 353.4K | 37,000 | — | ↗ |
| 2023-12-07 | Davidson Nancy | Director | A-Award | A | Stock Option (Right to Buy) | 74,000 | 9.55 | 706.7K | 74,000 | — | ↗ |
| 2023-12-07 | Cox Troy | Director | A-Award | A | Stock Option (Right to Buy) | 37,000 | 9.55 | 353.4K | 37,000 | — | ↗ |
| 2023-12-07 | Campoy Carlos | Director | A-Award | A | Stock Option (Right to Buy) | 37,000 | 9.55 | 353.4K | 37,000 | — | ↗ |
| 2023-06-30 | Campoy Carlos | Director | A-Award | A | Stock Option (Right to Buy) | 50,000 | 8.64 | 432.0K | 50,000 | — | ↗ |
| 2023-06-16 | EcoR1 Capital, LLC | 10% Owner | P-Purchase | A | Common Stock | 3,350,000 | 8.12 | 27.20M | 13,437,473 | — | ↗ |
| 2023-04-10 | Miller Derek John Michael | Director | A-Award | A | Stock Option (Right to Buy) | 50,000 | 9.37 | 468.5K | 50,000 | — | ↗ |
| 2023-03-28 | EcoR1 Capital, LLC | 10% Owner | P-Purchase | A | Common Stock | 200,000 | 8.00 | 1.60M | 10,087,473 | — | ↗ |
| 2023-03-10 | Klompas Neil A | Officer | M-Exempt | A | Common Stock | 2,708 | 0.00 | — | 20,009 | — | ↗ |
| 2023-01-20 | EcoR1 Capital, LLC | Director | P-Purchase | A | Common Stock | 163,400 | 9.88 | 1.62M | 9,887,473 | — | ↗ |
| 2023-01-19 | EcoR1 Capital, LLC | Director | P-Purchase | A | Common Stock | 144,100 | 9.49 | 1.37M | 9,724,073 | — | ↗ |
| 2023-01-18 | EcoR1 Capital, LLC | Director | P-Purchase | A | Common Stock | 203,000 | 10.00 | 2.03M | 9,579,973 | — | ↗ |
| 2023-01-17 | EcoR1 Capital, LLC | Director | P-Purchase | A | Common Stock | 440,000 | 9.80 | 4.31M | 9,376,973 | — | ↗ |
| 2023-01-13 | EcoR1 Capital, LLC | Director | P-Purchase | A | Common Stock | 342,100 | 9.81 | 3.35M | 8,936,973 | — | ↗ |
| 2023-01-11 | EcoR1 Capital, LLC | Director | P-Purchase | A | Common Stock | 106,300 | 7.87 | 836.9K | 8,594,873 | — | ↗ |
| 2023-01-10 | EcoR1 Capital, LLC | Director | P-Purchase | A | Common Stock | 920,000 | 7.65 | 7.04M | 8,488,573 | — | ↗ |
| 2023-01-05 | Galbraith Kenneth | Director / Officer | A-Award | A | Stock Option (Right to Buy) | 215,000 | 8.00 | 1.72M | 215,000 | — | ↗ |
| 2022-12-22 | Galbraith Kenneth | Director / Officer | A-Award | A | Restricted Stock Unit | 100,000 | 0.00 | — | 100,000 | — | ↗ |
| 2022-12-21 | Sacks Natalie | Director | A-Award | A | Stock Option (Right to Buy) | 25,000 | 8.75 | 218.8K | 25,000 | — | ↗ |
| 2022-12-21 | RENTON HOLLINGS | Director | A-Award | A | Stock Option (Right to Buy) | 25,000 | 8.75 | 218.8K | 25,000 | — | ↗ |
| 2022-12-21 | Neu Kelvin | Director | A-Award | A | Stock Option (Right to Buy) | 25,000 | 8.75 | 218.8K | 25,000 | — | ↗ |
| 2022-12-21 | Mahony Susan | Director | A-Award | A | Stock Option (Right to Buy) | 25,000 | 8.75 | 218.8K | 25,000 | — | ↗ |
| 2022-12-21 | Hillan Kenneth J. | Director | A-Award | A | Stock Option (Right to Buy) | 25,000 | 8.75 | 218.8K | 25,000 | — | ↗ |
| 2022-12-21 | Cox Troy | Director | A-Award | A | Stock Option (Right to Buy) | 25,000 | 8.75 | 218.8K | 25,000 | — | ↗ |
| 2022-11-10 | Josephson Neil | Officer | M-Exempt | A | Common Stock | 5,885 | 0.00 | — | 16,924 | — | ↗ |
| 2022-10-31 | EcoR1 Capital, LLC | 10% Owner | — | I | Common Stock | 0 | 0.00 | — | 7,568,573 | — | ↗ |
| 2022-10-13 | Redmile Group, LLC | 10% Owner | — | — | Common Stock, par value $0.00001 per share | 0 | 0.00 | — | 6,045,437 | I | ↗ |
| 2022-07-18 | Moore Paul Andrew | Officer | A-Award | A | Stock Option (Right to Buy) | 200,000 | 0.00 | — | 200,000 | — | ↗ |
| 2022-07-05 | Klompas Neil A | Officer | A-Award | A | Common Shares | 1,525 | 4.51 | 6.9K | 14,801 | — | ↗ |
| 2022-07-05 | Josephson Neil | Officer | A-Award | A | Common Shares | 1,525 | 4.51 | 6.9K | 11,039 | — | ↗ |
| 2022-03-10 | Klompas Neil A | Officer | M-Exempt | A | Common Shares | 2,708 | 0.00 | — | 16,255 | — | ↗ |
| 2022-03-10 | Josephson Neil | Officer | M-Exempt | A | Common Shares | 729 | 0.00 | — | 7,848 | — | ↗ |
| 2022-03-10 | Astle Christopher | Officer | A-Award | A | Stock Option (Right to Buy) | 125,000 | 0.00 | — | 125,000 | — | ↗ |
| 2022-02-24 | Astle Christopher | Officer | — | D | Common Shares | 0 | 0.00 | — | 670 | — | ↗ |
| 2022-01-15 | Galbraith Kenneth | Director / Officer | A-Award | A | Stock Option (Right to Buy) | 500,000 | 14.97 | 7.49M | 500,000 | — | ↗ |
| 2022-01-07 | Polverino Anthony J. | Officer | A-Award | A | Common Shares | 74 | 13.94 | 1.0K | 36,407 | — | ↗ |
| 2022-01-07 | Klompas Neil A | Officer | A-Award | A | Common Shares | 277 | 13.94 | 3.9K | 11,047 | — | ↗ |
| 2022-01-07 | Josephson Neil | Officer | A-Award | A | Common Shares | 65 | 13.94 | 906.10 | 2,119 | — | ↗ |
| 2021-11-10 | Josephson Neil | Officer | A-Award | A | Stock Option (Right to Buy) | 105,943 | 21.18 | 2.24M | 105,943 | — | ↗ |
| 2021-08-31 | Polverino Anthony J. | Officer | M-Exempt | D | Stock Option (Right to Buy) | 4,900 | 15.00 | 73.5K | 77,600 | — | ↗ |
| 2021-07-16 | Tehrani Ali | Director / Officer | M-Exempt | A | Common Shares | 41,191 | 4.26 | 175.7K | 301,516 | — | ↗ |
| 2021-07-15 | Tehrani Ali | Director / Officer | M-Exempt | A | Common Shares | 3,800 | 4.27 | 16.2K | 264,125 | — | ↗ |
| 2021-07-12 | Tehrani Ali | Director / Officer | M-Exempt | A | Common Shares | 12,669 | 4.31 | 54.6K | 272,994 | — | ↗ |
| 2021-07-06 | Priour James | Officer | A-Award | A | Common Shares | 510 | 29.49 | 15.0K | 2,513 | — | ↗ |
| 2021-07-06 | Polverino Anthony J. | Officer | A-Award | A | Common Shares | 454 | 29.49 | 13.4K | 31,433 | — | ↗ |
| 2021-07-06 | O'Driscoll Kathryn | Officer | A-Award | A | Common Shares | 510 | 29.49 | 15.0K | 6,350 | — | ↗ |
| 2021-07-06 | Klompas Neil A | Officer | A-Award | A | Common Shares | 299 | 29.49 | 8.8K | 10,770 | — | ↗ |
| 2021-07-06 | Josephson Neil | Officer | A-Award | A | Common Shares | 461 | 29.49 | 13.6K | 2,054 | — | ↗ |
| 2021-05-16 | Josephson Neil | Officer | — | D | Common Shares | 0 | 0.00 | — | 1,593 | — | ↗ |
| 2021-05-06 | Zoth Lota S. | Director | A-Award | A | Stock Option (Right to Buy) | 9,000 | 29.49 | 265.4K | 9,000 | — | ↗ |
| 2021-05-06 | Sacks Natalie | Director | A-Award | A | Stock Option (Right to Buy) | 9,000 | 29.49 | 265.4K | 9,000 | — | ↗ |
| 2021-05-06 | RENTON HOLLINGS | Director | A-Award | A | Stock Option (Right to Buy) | 9,000 | 29.49 | 265.4K | 9,000 | — | ↗ |
| 2021-05-06 | Neu Kelvin | Director | A-Award | A | Stock Option (Right to Buy) | 9,000 | 29.49 | 265.4K | 9,000 | — | ↗ |
| 2021-05-06 | Mahony Susan | Director | A-Award | A | Stock Option (Right to Buy) | 9,000 | 29.49 | 265.4K | 9,000 | — | ↗ |
| 2021-05-06 | Hillan Kenneth J. | Director | A-Award | A | Stock Option (Right to Buy) | 9,000 | 29.49 | 265.4K | 9,000 | — | ↗ |
| 2021-05-06 | Cox Troy | Director | A-Award | A | Stock Option (Right to Buy) | 9,000 | 29.49 | 265.4K | 9,000 | — | ↗ |
| 2021-04-13 | Priour James | Officer | M-Exempt | D | Restricted Stock Unit | 2,266 | 0.00 | — | 4,534 | — | ↗ |
| 2021-03-15 | O'Driscoll Kathryn | Officer | S-Sale | D | Common Shares | 786 | 34.72 | 27.3K | 5,003 | — | ↗ |
| 2021-03-10 | Tehrani Ali | Director / Officer | M-Exempt | D | Restricted Stock Unit | 7,708 | 0.00 | — | 15,417 | — | ↗ |
| 2021-03-10 | Priour James | Officer | A-Award | A | Restricted Stock Unit | 6,250 | 0.00 | — | 6,250 | — | ↗ |
| 2021-03-10 | Polverino Anthony J. | Officer | M-Exempt | D | Restricted Stock Unit | 2,500 | 0.00 | — | 5,000 | — | ↗ |
| 2021-03-10 | O'Driscoll Kathryn | Officer | A-Award | A | Stock Option (Right to Buy) | 30,000 | 34.82 | 1.04M | 30,000 | — | ↗ |
| 2021-03-10 | Klompas Neil A | Officer | A-Award | A | Restricted Stock Unit | 8,125 | 0.00 | — | 8,125 | — | ↗ |
| 2021-03-10 | HAUSMAN DIANA | Officer | M-Exempt | D | Restricted Stock Unit | 2,500 | 0.00 | — | 5,000 | — | ↗ |
| 2021-02-12 | O'Driscoll Kathryn | Officer | M-Exempt | A | Common Shares | 2,083 | 34.24 | 71.3K | 5,003 | — | ↗ |
| 2021-01-25 | Priour James | Officer | — | D | Common Shares | 0 | 0.00 | — | 687 | — | ↗ |
| 2021-01-08 | Klompas Neil A | Officer | A-Award | A | Common Shares | 284 | 30.92 | 8.8K | 9,396 | — | ↗ |
| 2021-01-07 | Polverino Anthony J. | Officer | A-Award | A | Common Shares | 48 | 30.92 | 1.5K | 29,527 | — | ↗ |
| 2021-01-07 | HAUSMAN DIANA | Officer | A-Award | A | Common Shares | 207 | 30.92 | 6.4K | 3,925 | — | ↗ |
| 2020-12-09 | Klompas Neil A | Officer | M-Exempt | D | Stock Option (Right to Buy) | 8,380 | 4.19 | 35.1K | 0 | — | ↗ |
| 2020-12-07 | Tehrani Ali | Director / Officer | S-Sale | D | Common Shares | 850 | 56.16 | 47.7K | 55,511 | — | ↗ |
| 2020-12-04 | HAUSMAN DIANA | Officer | S-Sale | D | Common Shares | 6,032 | 55.12 | 332.5K | 3,718 | — | ↗ |
| 2020-12-02 | HAUSMAN DIANA | Officer | S-Sale | D | Common Shares | 701 | 55.01 | 38.6K | 3,718 | — | ↗ |
| 2020-12-01 | HAUSMAN DIANA | Officer | S-Sale | D | Common Shares | 18,267 | 55.19 | 1.01M | 3,718 | — | ↗ |
| 2020-11-18 | O'Driscoll Kathryn | Officer | M-Exempt | D | Stock Option (Right to Buy) | 2,920 | 34.24 | 100.0K | 97,080 | — | ↗ |
| 2020-11-02 | Tehrani Ali | Director / Officer | S-Sale | D | Common Shares | 3,500 | 39.04 | 136.6K | 56,361 | — | ↗ |
| 2020-09-14 | HAUSMAN DIANA | Officer | S-Sale | D | Common Shares | 40,000 | 45.00 | 1.80M | 3,718 | — | ↗ |
| 2020-07-02 | Polverino Anthony J. | Officer | A-Award | A | Common Shares | 488 | 30.66 | 15.0K | 29,479 | — | ↗ |
| 2020-07-02 | Klompas Neil A | Officer | A-Award | A | Common Shares | 277 | 30.66 | 8.5K | 9,112 | — | ↗ |
| 2020-07-02 | HAUSMAN DIANA | Officer | A-Award | A | Common Shares | 367 | 30.66 | 11.3K | 3,718 | — | ↗ |
| 2020-05-08 | Zoth Lota S. | Director | A-Award | A | Stock Option (Right to Buy) | 9,000 | 35.49 | 319.4K | 9,000 | — | ↗ |
| 2020-05-08 | Sacks Natalie | Director | A-Award | A | Stock Option (Right to Buy) | 9,000 | 35.49 | 319.4K | 9,000 | — | ↗ |
| 2020-05-08 | RENTON HOLLINGS | Director | A-Award | A | Stock Option (Right to Buy) | 9,000 | 35.49 | 319.4K | 9,000 | — | ↗ |
| 2020-05-08 | Mahony Susan | Director | A-Award | A | Stock Option (Right to Buy) | 9,000 | 35.49 | 319.4K | 9,000 | — | ↗ |
| 2020-05-08 | Hillan Kenneth J. | Director | A-Award | A | Stock Option (Right to Buy) | 9,000 | 35.49 | 319.4K | 9,000 | — | ↗ |
| 2020-05-08 | Cox Troy | Director | A-Award | A | Stock Option (Right to Buy) | 9,000 | 35.49 | 319.4K | 9,000 | — | ↗ |
| 2020-05-08 | BAKER BROS. ADVISORS LP | Director | A-Award | A | Non-Qualified Stock Option (right to buy) | 9,000 | 35.49 | 319.4K | 9,000 | — | ↗ |
| 2020-04-13 | Tehrani Ali | Director / Officer | M-Exempt | A | Common Shares | 1,000 | 3.85 | 3.9K | 257,009 | — | ↗ |
| 2020-04-03 | Tehrani Ali | Director / Officer | P-Purchase | A | Common Shares | 80 | 33.39 | 2.7K | 59,861 | — | ↗ |
| 2020-03-16 | Neu Kelvin | Director | — | — | — | 0 | 0.00 | — | 0 | — | ↗ |
| 2020-03-16 | BAKER BROS. ADVISORS LP | Director | — | I | Common Stock | 0 | 0.00 | — | 168,252 | — | ↗ |
| 2020-03-10 | Tehrani Ali | Director / Officer | A-Award | A | Restricted Stock Unit | 23,125 | 0.00 | — | 23,125 | — | ↗ |
| 2020-03-10 | Polverino Anthony J. | Officer | A-Award | A | Restricted Stock Unit | 7,500 | 0.00 | — | 7,500 | — | ↗ |
| 2020-03-10 | O'Driscoll Kathryn | Officer | A-Award | A | Restricted Stock Unit | 4,063 | 0.00 | — | 4,063 | — | ↗ |
| 2020-03-10 | Klompas Neil A | Officer | A-Award | A | Restricted Stock Unit | 7,500 | 0.00 | — | 7,500 | — | ↗ |
| 2020-03-10 | HAUSMAN DIANA | Officer | A-Award | A | Restricted Stock Unit | 7,500 | 0.00 | — | 7,500 | — | ↗ |
| 2020-01-27 | Cox Troy | Director | P-Purchase | A | Common Shares | 7,500 | 46.50 | 348.8K | 7,500 | — | ↗ |
| 2020-01-08 | Polverino Anthony J. | Officer | A-Award | A | Common Shares | 371 | 19.54 | 7.2K | 28,991 | — | ↗ |
| 2020-01-08 | Klompas Neil A | Officer | A-Award | A | Common Shares | 394 | 19.54 | 7.7K | 8,835 | — | ↗ |
| 2020-01-08 | HAUSMAN DIANA | Officer | A-Award | A | Common Shares | 332 | 19.54 | 6.5K | 3,351 | — | ↗ |
| 2019-12-12 | Polverino Anthony J. | Officer | — | D | Stock Option (Right to Buy) | 110,000 | 15.00 | 1.65M | 0 | — | ↗ |
Executive team
Top executives
EBIT / Employee
-309.5K
Shares Outstanding
74.30M
Executive compensation
Executive compensation (annual)
| # | Year | Executive | Salary | Bonus | Stock award | Option award | Incentive | Other | Total | % Stock- based |
Filing |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 2024 | Kenneth Galbraith, CEO , President & Chair | 654.8K | — | 2.11M | 1.99M | 361.7K | 139.5K | 5.25M | 78.00% | ↗ |
| 2 | 2024 | Leone Patterson, Exec. VP, Chief Business Officer & CFO | 161.7K | 50.0K | — | 2.59M | 99.8K | 6.1K | 2.91M | 89.08% | ↗ |
| 3 | 2023 | Kenneth Galbraith, CEO , President & Chair | 625.5K | — | 1.14M | 1.19M | 321.7K | 89.1K | 3.37M | 69.30% | ↗ |
| 4 | 2023 | Kenneth Galbraith, Chair, President & CEO | 625.5K | — | 1.14M | 1.19M | 321.7K | 89.1K | 3.37M | 69.30% | ↗ |
| 5 | 2023 | Neil Klompas, Former President & COO | 321.6K | — | 468.0K | 328.4K | — | 1.01M | 2.13M | 37.46% | ↗ |
| 6 | 2023 | Paul Moore, CSO | 465.8K | — | 412.0K | 397.6K | 182.1K | 224.8K | 1.68M | 48.12% | ↗ |
| 7 | 2023 | Christopher Astle, Former SVP & CFO | 410.1K | — | 252.0K | 257.6K | 124.9K | 147.2K | 1.19M | 42.76% | ↗ |
| 8 | 2022 | Kenneth Galbraith, Chair & CEO (current President) | 582.5K | — | 879.0K | 5.04M | 537.7K | 81.2K | 7.13M | 83.14% | ↗ |
| 9 | 2022 | Kenneth Galbraith, Chair, President & CEO | 582.5K | — | 879.0K | 5.04M | 537.7K | 81.2K | 7.13M | 83.14% | ↗ |
| 10 | 2022 | Neil Klompas, Former President & COO | 503.8K | — | — | 950.0K | 330.7K | 23.9K | 1.81M | 52.53% | ↗ |
| 11 | 2022 | Christopher Astle, SVP & CFO | 358.7K | — | — | 593.8K | 203.0K | 159.4K | 1.32M | 45.15% | ↗ |
| 12 | 2022 | Christopher Astle, Former SVP & CFO | 358.7K | — | — | 593.8K | 203.0K | 159.4K | 1.32M | 45.15% | ↗ |
| 13 | 2022 | Ali Tehrani, Former President & CEO | 105.7K | — | — | — | — | 858.5K | 964.2K | 0.00% | ↗ |
| 14 | 2021 | Ali Tehrani, Former President & CEO | 593.1K | — | 870.5K | 3.63M | — | 21.9K | 5.11M | 87.97% | ↗ |
| 15 | 2021 | Neil Klompas, Former President & COO | 437.1K | — | 282.9K | 1.18M | — | 2.3K | 1.90M | 76.88% | ↗ |
| 16 | 2020 | Ali Tehrani, President & CEO | 573.0K | — | 814.0K | 3.19M | 283.7K | 21.0K | 4.88M | 82.01% | ↗ |
| 17 | 2020 | Diana Hausman, Chief Medical Officer | 449.9K | — | 264.0K | 1.03M | 166.5K | 20.2K | 1.93M | 67.08% | ↗ |
| 18 | 2020 | Anthony Polverino, Executive VP, Early Development & Chief Scientific Officer | 428.0K | — | 264.0K | 1.03M | 158.4K | 20.3K | 1.90M | 68.13% | ↗ |
| 19 | 2020 | Neil Klompas, Exec. VP, Business Operations & CFO | 424.4K | — | 264.0K | 1.03M | 163.4K | 2.0K | 1.89M | 68.74% | ↗ |
| 20 | 2020 | Kathryn O’Driscoll, Chief People Officer | 350.0K | — | 143.0K | 559.7K | 129.5K | 17.7K | 1.20M | 58.56% | ↗ |
| 21 | 2019 | Ali Tehrani, President & CEO | 540.8K | — | — | 2.38M | 341.9K | 20.2K | 3.28M | 72.46% | ↗ |
| 22 | 2019 | Ali Tehrani, President and Chief Executive Officer | 540.8K | — | — | 2.38M | 341.9K | 20.2K | 3.28M | 72.46% | ↗ |
| 23 | 2019 | Kathryn O’Driscoll, Chief People Officer | 75.6K | — | — | 2.28M | 33.3K | 36.00 | 2.39M | 95.45% | ↗ |
| 24 | 2019 | Neil Klompas, Exec. VP, Business Operations & CFO | 379.1K | — | — | 1.06M | 172.4K | 12.6K | 1.62M | 65.27% | ↗ |
| 25 | 2019 | Neil Klompas, Executive Vice President, Business Operations and Chief Financial Officer | 379.1K | — | — | 1.06M | 172.4K | 12.6K | 1.62M | 65.27% | ↗ |
| 26 | 2019 | Diana Hausman, Chief Medical Officer | 432.6K | — | — | 758.0K | 192.5K | 21.3K | 1.40M | 53.97% | ↗ |
| 27 | 2019 | Anthony Polverino, Executive VP, Early Development & Chief Scientific Officer | 400.0K | — | — | 758.0K | 178.0K | 384.00 | 1.34M | 56.72% | ↗ |
| 28 | 2019 | Anthony Polverino, Executive Vice President, Early Development and Chief Scientific Officer | 400.0K | — | — | 758.0K | 178.0K | 384.00 | 1.34M | 56.72% | ↗ |
| 29 | 2018 | Ali Tehrani, President & CEO | 510.3K | — | — | 1.81M | 280.5K | 17.7K | 2.61M | 69.07% | ↗ |
| 30 | 2018 | Ali Tehrani, President and Chief Executive Officer | 510.3K | 280.5K | — | 1.81M | — | 17.7K | 2.61M | 69.07% | ↗ |
| 31 | 2018 | Anthony Polverino, Executive VP, Early Development & Chief Scientific Officer | 113.6K | — | — | 1.06M | 43.9K | 96.00 | 1.21M | 87.02% | ↗ |
| 32 | 2018 | Anthony Polverino, Executive Vice President, Early Development and Chief Scientific Officer | 113.6K | 43.9K | — | 1.06M | — | 96.00 | 1.21M | 87.02% | ↗ |
| 33 | 2018 | Diana Hausman, Chief Medical Officer | 416.0K | — | — | 541.5K | 156.5K | 15.5K | 1.13M | 47.94% | ↗ |
| 34 | 2018 | Neil Klompas, Chief Financial Officer | 357.7K | 137.6K | — | 541.5K | — | 13.1K | 1.05M | 51.57% | ↗ |
| 35 | 2018 | Neil Klompas, Exec. VP, Business Operations & CFO | 357.7K | — | — | 541.5K | 137.6K | 13.1K | 1.05M | 51.57% | ↗ |
| 36 | 2017 | Ali Tehrani, President and Chief Executive Officer | 397.3K | 213.8K | — | 1.03M | — | 13.6K | 1.65M | 62.24% | ↗ |
| 37 | 2017 | Diana Hausman, Chief Medical Officer | 400.0K | 133.0K | — | 485.9K | — | 22.4K | 1.04M | 46.66% | ↗ |
| 38 | 2017 | Neil Klompas, Chief Financial Officer | 285.2K | 108.1K | — | 573.5K | — | 17.4K | 984.2K | 58.27% | ↗ |
CEO compensation breakdown
Proxy statements
Recent SEC filings
Executive team
| Name | Title | Compensation | Gender |
|---|---|---|---|
| Kenneth H. Galbraith | Chairman of the Board, Chief Executive Officer & President | 2M | male |
| Paul Moore | Chief Scientific Officer | 998.4K | — |
| Kristin Stafford | Executive VP & CFO | — | female |
| Laura O'Connor | Senior VP & Chief Human Resources Officer | — | female |
| Lindsey Foulkes | SVP of Corporate Development & Strategy | — | — |
| Mark Hollywood | Executive VP & Chief Operating Officer | — | male |
| Sabeen Mekan | SVP & Chief Medical Officer | — | — |
| Scott Platshon | Executive VP & Chief Business Officer | — | male |
| Bijal Desai | Senior Vice President of Finance | — | female |
| Shrinal Inamdar | VP of Investor Relations | — | female |
| Diana Papove | Vice President of Corporate Communications | — | female |
ESG Rating
ESG Score History BIOTECHNOLOGY
Benchmark vs Sector
Senate Trading Activity
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House Trading Activity
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Market share among peers
Peer comparison — filtered group (TTM)
Your opinion
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Community Opinion for ZYME
Short-term intention
Target Price Distribution
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