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Vivoryon Therapeutics N.V. (VVY.AS)

EUR1.19 -0.03 (-2.46%)
DE AMS Healthcare Biotechnology
Address Weinbergweg 22 6120
Halle, DE
CEO Frank T. Weber
IPO 2014-10-27
ISIN NL00150002Q7

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Also trades on Euronext Amsterdam · VVY.AS (EUR) London Stock Exchange · 0R3M.L (EUR)
Description

Vivoryon Therapeutics N.V. is a clinical-stage biopharmaceutical firm dedicated to discovering and developing novel treatments for Alzheimer's disease. The company's therapeutic pipeline primarily focuses on mitigating Alzheimer's by targeting and preventing the formation of toxic pyroglutamate-Abeta (pGlu-Abeta). Its flagship compound, PQ912, a small molecule QC inhibitor, has successfully concluded Phase IIb clinical trials for both Alzheimer's disease and various cancer indications. Additionally, Vivoryon is advancing PQ1565, another small molecule (a glutaminyl-peptide cyclotransferase-like inhibitor), through preclinical development, specifically for cancer therapy. Beyond its small molecule programs, the company is also developing a monoclonal antibody designed to improve the clearance of pGlu-Abeta from the body. To bolster its research and development efforts, Vivoryon has forged several key partnerships, including collaborations with the University Medical Center Schleswig-Holstein for cancer immunotherapy discovery, Nordic Bioscience for the clinical progression of PQ912 in Alzheimer's, and the Fraunhofer Institute for cell therapy and immunology. Furthermore, a significant regional licensing agreement with Simcere Pharmaceutical Group Ltd. aims to develop and commercialize treatments for Alzheimer's disease by targeting the neurotoxic amyloid species N3pE (pGlu-Abeta). Established in 1997, Vivoryon Therapeutics N.V. maintains its headquarters in Halle, Germany.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
EUR1.19 -0.03 (-2.46%)
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Volume Profile
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Liquidity & share structure
Average Volume
50.9K
Beta
1.39
Float Shares
23.39M
Free Float %
79.0%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
+5.44% +0.80% -3.45% -11.27% -21.25% -11.27% -26.74% -91.39% -90.70% -93.42% -93.57%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
vs.
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Price Targets & DCF
Current price
1.19
DCF (Unlevered) 0.19 -83.7%
DCF (Levered) 0.20 -82.8%

DCF figures are point estimates: small changes in growth or discount-rate assumptions move them materially. Read them as a reference, not a precise target.

Ratings Trend (MoM) 100% Bullish
Rating 2026-05 Change
Strong Buy 0 0
Buy 1 0
Hold 0 0
Sell 0 0
Strong Sell 0 0
Quality scores
Altman Z-Score
-37.41
Distress
Piotroski F-Score
2 / 9
Weak
MOAT Score
2 / 10
No MOAT
Composite Rating
C
Overall Score
2 / 5
Medium
DCF Score
3 / 5
Medium
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
3 / 5
Medium
P/E Score
1 / 5
Low
P/Book Score
1 / 5
Low
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
    Q4'25: +100.0% (vs Q4'23)
  • EPS growth Biotechnology: +29.7%
    +58.2% Q4'25: +83.3% (vs Q4'23)
  • FCF margin FCF growth · Biotechnology: +16.2%
  • EBIT margin Biotechnology: +0.0%
  • ROIC Biotechnology: -16.1%
    Q4'25: +1,864.3% (vs Q4'23)
  • Share dilution Biotechnology: -3.4%
    +3.7% Q4'25: +16.7% (vs Q4'23)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    -0.01× Q4'25: -0.01× (vs Q4'23)
Valuation Multiples From To
DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (1.38) × ERP
WACC = 100% × Ke + 0% × Kd (41.7%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Intrinsic value (base): 0.19 Current price: 1.19
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2024
actual
Dec 2025
actual
Dec 2026
1 Rev. Ana.
1 EPS Ana.
Dec 2027
1 Rev. Ana.
1 EPS Ana.
Dec 2028
1 EPS Ana.
Revenue
100.00
100.00 – 100.00
339.70M
339.70M – 339.70M
+339,699,900.0% YoY
— – —
-100.0% YoY
EBITDA
-20.34M
-9.03M
60.00
60.00 – 60.00
203.82M
203.82M – 203.82M
+339,699,900.0% YoY
— – —
-100.0% YoY
EBIT
-20.48M
-9.18M
60.00
60.00 – 60.00
203.82M
203.82M – 203.82M
+339,699,900.0% YoY
— – —
-100.0% YoY
Net Income
-20.57M
est: -23.43M (+12.2%)
-8.85M
est: -18.89M (+53.1%)
-18.89M
-18.89M – -18.89M
+0.0% YoY
-15.11M
-15.11M – -15.11M
+20.0% YoY
-16.19M
-16.19M – -16.19M
-7.1% YoY
SGA
6.76M
4.65M
50.00
50.00 – 50.00
170.08M
170.08M – 170.08M
+340,164,084.0% YoY
— – —
-100.0% YoY
EPS
-0.79
est: -0.90 (+12.2%)
-0.33
est: -0.70 (+52.9%)
-0.70
-0.70 – -0.70
+0.0% YoY
-0.56
-0.56 – -0.56
+20.0% YoY
-0.60
-0.60 – -0.60
-7.1% YoY
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-29 C 2/5 3/5 1/5 1/5 3/5 1/5 1/5
2026-05-28 C 2/5 3/5 1/5 1/5 3/5 1/5 1/5
2026-05-27 C 2/5 3/5 1/5 1/5 3/5 1/5 1/5
2026-05-26 C 2/5 3/5 1/5 1/5 3/5 1/5 1/5
2026-05-25 C 2/5 3/5 1/5 1/5 3/5 1/5 1/5
2026-05-22 C 2/5 3/5 1/5 1/5 3/5 1/5 1/5
2026-05-21 C 2/5 3/5 1/5 1/5 3/5 1/5 1/5
2026-05-20 C 2/5 3/5 1/5 1/5 3/5 1/5 1/5
2026-05-19 C 2/5 3/5 1/5 1/5 3/5 1/5 1/5
2026-05-18 C 2/5 3/5 1/5 1/5 3/5 1/5 1/5
2026-05-15 C 2/5 3/5 1/5 1/5 3/5 1/5 1/5
2026-05-14 C 2/5 3/5 1/5 1/5 3/5 1/5 1/5
2026-05-13 C 2/5 3/5 1/5 1/5 3/5 1/5 1/5
2026-05-12 C 2/5 3/5 1/5 1/5 3/5 1/5 1/5
2026-05-11 C 2/5 3/5 1/5 1/5 3/5 1/5 1/5
2026-05-08 C 2/5 3/5 1/5 1/5 3/5 1/5 1/5
2026-05-07 C 2/5 3/5 1/5 1/5 3/5 1/5 1/5
2026-05-06 C 2/5 3/5 1/5 1/5 3/5 1/5 1/5
2026-05-05 C 2/5 3/5 1/5 1/5 3/5 1/5 1/5
2026-05-04 C 2/5 3/5 1/5 1/5 3/5 1/5 1/5
2026-04-30 C 2/5 3/5 1/5 1/5 3/5 1/5 1/5
2026-04-29 C 2/5 3/5 1/5 1/5 3/5 1/5 1/5
2026-04-28 C 2/5 3/5 1/5 1/5 3/5 1/5 1/5
2026-04-27 C 2/5 3/5 1/5 1/5 3/5 1/5 1/5
2026-04-24 C- 1/5 3/5 1/5 1/5 2/5 1/5 1/5
2026-04-23 C- 1/5 3/5 1/5 1/5 2/5 1/5 1/5
2026-04-22 C- 1/5 3/5 1/5 1/5 2/5 1/5 1/5
2026-04-21 C- 1/5 3/5 1/5 1/5 2/5 1/5 1/5
2026-04-20 C- 1/5 3/5 1/5 1/5 2/5 1/5 1/5
2026-04-17 C- 1/5 3/5 1/5 1/5 2/5 1/5 1/5
2026-04-16 C- 1/5 3/5 1/5 1/5 2/5 1/5 1/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
-24.44M
OE per share TTM
-0.93
Owner's Yield
-67.76%
Maintenance CapEx ratio
Maint CapEx / Avg PPE
22.9%

Ownership Overview

Ownership breakdown

Ownership breakdown not available.

At a glance
Institutional holders
Total invested
Insider transactions (90d)
0
Beneficial owners (>5%)
0
Beneficial owners (>5%)

No beneficial ownership filings recorded.

Institutional Activity (13F)

Institutional ownership trend

Institutional history not available.

Top institutional holders

Top holders not available.

ETF Ownership

Top ETFs holding this stock

This company is not held by any ETF in our universe.

Insider Activity

Insider Activity — Latest Quarter

No insider activity available.

Insider buys vs sells (history)

Insider history not available.

Recent insider transactions

No recent insider transactions.

Executive team

Top executives
Shares Outstanding
29.61M

Executive compensation

Executive compensation (annual)

Executive compensation not available.

CEO compensation breakdown

No CEO compensation history available.

Proxy statements

Proxy statements (DEF 14A)

No proxy statements available for this company yet.

Recent SEC filings

Recent SEC filings

No SEC filings available for this company yet.

Executive team

NameTitleCompensationGender
Michael Schaeffer Chief Business Officer & Executive Director 341.0K
Frank T. Weber MD, CEO, Chief Medical Officer & Executive Director 329.0K male
Hendrik Liebers Advisor 319.2K
Julia Neugebauer Head of Investor Relations & Communications, COO & Executive Board Member 259.0K
Konrad Glund Co-Founder & Advisor 222.1K
Marcus Irsfeld Chief Financial Officer & Executive Director 109.0K male
Manuela Bader Director of Investor Relations & Communications
ESG Score History

No data available for this company.

Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend history

Earnings history

Earnings reports

Stock splits