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Trevi Therapeutics, Inc. (TRVI)

USD16.52 -1.32 (-7.40%)
US NASDAQ Healthcare Biotechnology
Address 195 Church Street 6510
New Haven, CT, US
CEO Jennifer L. Good
IPO 2019-05-07
CIK 1563880 ISIN US89532M1018

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Description

Trevi Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on the advancement and commercialization of Haduvio, a potential treatment for debilitating neurologically mediated conditions. This orally administered, extended-release formulation of nalbuphine is currently undergoing Phase IIb/III clinical trials for chronic pruritus (severe itching) and persistent cough experienced by patients with idiopathic pulmonary fibrosis. Trevi Therapeutics also possesses a licensing agreement with Endo Pharmaceuticals Inc., granting it the rights to develop and market products containing nalbuphine hydrochloride in various formulations. Established in 2011, the company maintains its corporate headquarters in New Haven, Connecticut.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
USD16.52 -1.32 (-7.40%)
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Volume Profile
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Liquidity & share structure
Average Volume
2M
Beta
1.05
Float Shares
105.98M
Free Float %
74.7%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
+2.62% +4.64% +12.81% +36.01% +25.57% +18.85% +122.09% +425.80% +592.09% +88.59% +88.59%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
vs.
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Analyst Consensus (17 ratings, all time) Buy
Price Targets & DCF
Current price
16.52
Low 16.00 -3.1%
Consensus 22.50 +36.2%
Median 22.00 +33.2%
High 30.00 +81.6%
DCF (Unlevered) 0.11 -99.4%
DCF (Levered) 0.13 -99.2%

DCF figures are point estimates: small changes in growth or discount-rate assumptions move them materially. Read them as a reference, not a precise target.

Ratings Trend (MoM) 100% Bullish
Rating 2026-05 Change
Strong Buy 2 0
Buy 9 0
Hold 0 0
Sell 0 0
Strong Sell 0 0
Price Target Summary
Period # Analysts Avg Target
Last Month
Last Quarter
Last Year 4
19.25
+16.5%
All Time 7
14.43
-12.7%
Quality scores
Altman Z-Score
162.74
Safe zone
Piotroski F-Score
2 / 9
Weak
MOAT Score
3 / 10
No MOAT
Composite Rating
C-
Overall Score
1 / 5
Low
DCF Score
2 / 5
Medium
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
3 / 5
Medium
P/E Score
1 / 5
Low
P/Book Score
1 / 5
Low
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
  • EPS growth Biotechnology: +29.7%
    +38.3% Q1'26: -3.1% (vs Q1'25)
  • FCF margin FCF growth · Biotechnology: +16.2%
  • EBIT margin Biotechnology: +0.0%
  • ROIC Biotechnology: -16.1%
    Q1'26: -5,804.8% (vs Q1'25)
  • Share dilution Biotechnology: -3.4%
    +43.6% Q1'26: +23.8% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    -0.02× Q1'26: -0.01× (vs Q1'25)
Valuation Multiples From To
Price Forecast (3Y) From To
Model
Adjust
P/E
Theoretical Return — If Invested Today

* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.

DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (1.08) × ERP
WACC = 100% × Ke + 0% × Kd (4.1%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Intrinsic value (base): 0.11 Current price: 16.52
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2024
actual
Dec 2025
actual
Dec 2026
10 Rev. Ana.
6 EPS Ana.
Dec 2027
6 Rev. Ana.
8 EPS Ana.
Dec 2028
7 Rev. Ana.
9 EPS Ana.
Dec 2029
3 Rev. Ana.
3 EPS Ana.
Dec 2030
6 Rev. Ana.
3 EPS Ana.
Revenue
1.10M
1.10M – 1.10M
3.47M
3.47M – 3.47M
+215.8% YoY
31.87M
31.87M – 31.87M
+819.3% YoY
141.59M
141.59M – 141.59M
+344.3% YoY
417.03M
417.03M – 417.03M
+194.5% YoY
EBITDA
-47.79M
-42.68M
— – —
— – —
— – —
— – —
— – —
EBIT
-47.94M
-42.82M
— – —
— – —
— – —
— – —
— – —
Net Income
-47.91M
est: -50.73M (+5.6%)
-42.76M
est: -52.11M (+18.0%)
-79.75M
-81.35M – -42.13M
-53.0% YoY
-98.24M
-132.40M – -51.81M
-23.2% YoY
-91.42M
-172.66M – 155.25M
+6.9% YoY
-40.19M
-40.19M – -40.19M
+56.0% YoY
129.47M
129.47M – 129.47M
+422.1% YoY
SGA
12.15M
15.85M
— – —
— – —
— – —
— – —
— – —
EPS
-0.47
est: -0.51 (+7.3%)
-0.29
est: -0.36 (+20.4%)
-0.45
-0.56 – -0.29
-23.7% YoY
-0.56
-0.91 – -0.36
-23.3% YoY
-0.54
-1.19 – 1.07
+3.0% YoY
-0.28
-0.28 – -0.28
+48.6% YoY
0.89
0.89 – 0.89
+422.1% YoY
Recent Grade Changes (3M)
Date Firm Previous New Grade Action
2026-04-17 D. Boral Capital Buy Buy Maintain
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-11 C 2/5 2/5 1/5 1/5 4/5 1/5 1/5
2026-05-08 C 2/5 2/5 1/5 1/5 4/5 1/5 1/5
2026-05-07 C 2/5 2/5 1/5 1/5 4/5 1/5 1/5
2026-05-06 C 2/5 2/5 1/5 1/5 4/5 1/5 1/5
2026-05-05 C- 1/5 2/5 1/5 1/5 3/5 1/5 1/5
2026-05-04 C- 1/5 2/5 1/5 1/5 3/5 1/5 1/5
2026-05-01 C- 1/5 2/5 1/5 1/5 3/5 1/5 1/5
2026-04-30 C- 1/5 2/5 1/5 1/5 3/5 1/5 1/5
2026-04-29 C- 1/5 2/5 1/5 1/5 3/5 1/5 1/5
2026-04-28 C- 1/5 2/5 1/5 1/5 3/5 1/5 1/5
2026-04-27 C- 1/5 2/5 1/5 1/5 3/5 1/5 1/5
2026-04-24 C- 1/5 2/5 1/5 1/5 3/5 1/5 1/5
2026-04-23 C- 1/5 2/5 1/5 1/5 2/5 1/5 1/5
2026-04-22 C- 1/5 2/5 1/5 1/5 2/5 1/5 1/5
2026-04-21 C- 1/5 3/5 1/5 1/5 2/5 1/5 1/5
2026-04-20 C- 1/5 3/5 1/5 1/5 2/5 1/5 1/5
2026-04-17 C- 1/5 3/5 1/5 1/5 2/5 1/5 1/5
2026-04-16 C- 1/5 3/5 1/5 1/5 2/5 1/5 1/5
2026-04-15 C- 1/5 3/5 1/5 1/5 2/5 1/5 1/5

Owner Earnings

Owner's Earnings (history)

Owner's Earnings history not available.

Owner alignment
Owner's Earnings TTM
OE per share TTM
Owner's Yield
Maintenance CapEx ratio
Maint CapEx / Avg PPE

Ownership Overview

Ownership breakdown
At a glance
Institutional holders
26
Total invested
33.96M
Insider transactions (90d)
0
Beneficial owners (>5%)
50
Beneficial owners (>5%)
# Reporting person Amount owned % of class Sole voting Shared voting Sole dispositive Shared dispositive Type Citizenship Filing date SEC filing
1 16 GP, LLC 15.07M 18.70% 15.07M 15.07M OO Delaware 2024-11-08
2 A. Florence, Jr. 15.07M 18.70% 15.07M 15.07M IN States 2024-11-08
3 Behbahani 15.07M 18.70% 15.07M 15.07M IN States 2024-11-08
4 Chang 15.07M 18.70% 15.07M 15.07M IN States 2024-11-08
5 D. Sandell 15.07M 18.70% 15.07M 15.07M IN States 2024-11-08
6 Enterprise Associates 16, L.P. 15.07M 18.70% 15.07M 15.07M PN Delaware 2024-11-08
7 H. Makhzoumi 15.07M 18.70% 15.07M 15.07M IN States 2024-11-08
8 NEA 18 VGE GP, LLC 15.07M 18.70% 15.07M 15.07M OO Delaware 2024-11-08
9 NEA 18 Venture Growth Equity, L.P. 15.07M 18.70% 15.07M 15.07M PN Delaware 2024-11-08
10 NEA Partners 18 VGE, L.P. 15.07M 18.70% 15.07M 15.07M PN Delaware 2024-11-08
11 Partners 16, L.P. 15.07M 18.70% 15.07M 15.07M PN Delaware 2024-11-08
12 Walker 15.07M 18.70% 15.07M 15.07M IN States 2024-11-08
13 Baskett 14.13M 17.50% 14.13M 14.13M IN States 2024-11-08
14 David C. Ott 5.98M 9.99% 5.98M 5.98M IN Delaware 2022-10-07
15 O. Andreas Halvorsen 5.98M 9.99% 5.98M 5.98M IN Delaware 2022-10-07
16 Rose S. Shabet 5.98M 9.99% 5.98M 5.98M IN Delaware 2022-10-07
17 Viking Global Investors LP 5.98M 9.99% 5.98M 5.98M PN Delaware 2022-10-07
18 Viking Global Opportunities Parent GP LLC 5.98M 9.99% 5.98M 5.98M OO Delaware 2022-10-07
19 David Rosen 5.68M 9.49% 5.68M IN United States of America 2023-02-10
20 LP 5.68M 9.49% 5.68M IA, PN State of Delaware 2023-02-10
21 Viking Global Opportunities GP LLC 4.01M 6.69% 4.01M 4.01M OO Delaware 2022-10-07
22 Viking Global Opportunities Illiquid Investments Sub-Master LP 4.01M 6.69% 4.01M 4.01M PN Delaware 2022-10-07
23 Viking Global Opportunities Portfolio GP LLC 4.01M 6.69% 4.01M 4.01M OO Delaware 2022-10-07
24 Patrick J. Heron 3.82M 10.00% 3.82M 3.82M IN Delaware 2022-04-18
25 Fairmount Funds Management LLC 3.76M 9.90% 3.76M 3.76M IA Delaware 2022-04-21
26 Fairmount Healthcare Fund II L.P. 3.76M 9.90% 3.76M 3.76M PN Delaware 2022-04-21
27 Peter Harwin 3.76M 9.90% 3.76M 3.76M HC, IN United States 2022-04-21
28 Tomas Kiselak 3.76M 9.90% 3.76M 3.76M HC, IN Slovak Republic 2022-04-21
29 Koh, Bong 3.67M 9.99% 3.67M 3.67M IN United States 2022-04-21
30 Shah, Nimish 3.67M 9.99% 3.67M 3.67M IN United States 2022-04-21
31 VHCP Co-Investment Holdings II, LLC 3.67M 9.99% 3.67M 3.67M OO Delaware 2022-04-21
32 VHCP Co-Investment Holdings III, LLC 3.67M 9.99% 3.67M 3.67M OO Delaware 2022-04-21
33 VHCP Management EG, LLC 3.67M 9.99% 3.67M 3.67M OO Delaware 2022-04-21
34 VHCP Management II, LLC 3.67M 9.99% 3.67M 3.67M OO Delaware 2022-04-21
35 VHCP Management III, LLC 3.67M 9.99% 3.67M 3.67M OO Delaware 2022-04-21
36 Venrock Healthcare Capital Partners EG, L.P. 3.67M 9.99% 3.67M 3.67M PN Delaware 2022-04-21
37 Venrock Healthcare Capital Partners II, L.P. 3.67M 9.99% 3.67M 3.67M PN Delaware 2022-04-21
38 Venrock Healthcare Capital Partners III, L.P. 3.67M 9.99% 3.67M 3.67M PN Delaware 2022-04-21
39 Albert Cha 2.61M 7.00% 2.61M 2.61M IN Delaware 2022-04-18
40 Gilad Aharon 2.50M 4.20% 2.50M 2.50M IN ONTARIO, CANADA 2023-02-15
41 Rosalind Master Fund L.P. 2.50M 4.20% 2.50M 2.50M PN CAYMAN ISLANDS 2023-02-15
42 Steven Salamon 2.50M 4.20% 2.50M 2.50M IN ONTARIO, CANADA 2023-02-15
43 Viking Global Opportunities Drawdown (Aggregator) LP 1.97M 3.30% 1.97M 1.97M OO Delaware 2022-10-07
44 Viking Global Opportunities Drawdown GP LLC 1.97M 3.30% 1.97M 1.97M OO Delaware 2022-10-07
45 Viking Global Opportunities Drawdown Portfolio GP LLC 1.97M 3.30% 1.97M 1.97M OO Delaware 2022-10-07
46 FHMLS XI, L.L.C. 622.1K 1.70% 622.1K 622.1K OO Delaware 2022-04-18
47 FHMLS XI, L.P. 622.1K 1.70% 622.1K 622.1K PN Delaware 2022-04-18
48 Frazier Life Sciences XI, L.P. 622.1K 1.70% 622.1K 622.1K PN Delaware 2022-04-18
49 FHMLS X, L.L.C. 583.9K 1.60% 583.9K 583.9K OO Delaware 2022-04-18
50 FHMLS X, L.P. 583.9K 1.60% 583.9K 583.9K PN Delaware 2022-04-18

Institutional Activity (13F)

Institutional ownership trend From To
13F snapshot — 2026 Q1
Investors holding
26
-165 vs prev Q
New positions
6
Closed positions
162
Increased
15
Reduced
7
Put/Call ratio
0.00
Calls held
Puts held
Top institutional holders
# Investor Shares / Δ Mkt value / Δ Own% / Δ Weight% / Δ Avg px / Perf. Hold / Status
1 414.0K +414.0K (+100.0%) 5.18B +5.2B (+100.0%) 0.29% +0.285 pp 5.02% +5.016 pp USD12.52 +0.0% 1 qtrs NEW
2 NEA MANAGEMENT COMPANY, LLC 13.22M +— (+0.0%) 165.54M +44.6M (+36.8%) 9.11% -1.031 pp 8.44% +1.802 pp USD3.18 +293.7% 27 qtrs
3 FRAZIER LIFE SCIENCES MANAGEMENT, L.P. 10.26M +— (+0.0%) 128.45M +34.6M (+36.8%) 7.07% -0.800 pp 3.45% +0.637 pp USD2.53 +394.9% 15 qtrs
4 BLACKROCK, INC. 10.13M +225.1K (+2.3%) 126.78M +36.2M (+39.9%) 6.98% -0.617 pp 0.00% +0.001 pp USD5.58 +124.4% 6 qtrs
5 FMR LLC 6.50M +3.2M (+97.0%) 81.38M +51.2M (+169.5%) 4.48% +1.948 pp 0.00% +0.003 pp USD10.60 +18.1% 11 qtrs
6 VANGUARD GROUP INC 6.43M +607.7K (+10.4%) 80.56M +27.2M (+51.1%) 4.43% -0.036 pp 0.00% +0.000 pp USD4.88 +156.6% 27 qtrs
7 VIVO CAPITAL, LLC 5.09M +— (+0.0%) 63.79M +17.2M (+36.8%) 3.51% -0.397 pp 4.12% +0.372 pp USD4.74 +164.1% 6 qtrs
8 MARSHALL WACE, LLP 4.58M -261.2K (-5.4%) 57.35M +13.0M (+29.4%) 3.16% -0.558 pp 0.05% +0.007 pp USD7.66 +63.4% 6 qtrs
9 RUBRIC CAPITAL MANAGEMENT LP 3.77M -4.8M (-55.9%) 47.16M -30.9M (-39.6%) 2.60% -3.949 pp 0.56% -0.317 pp USD3.76 +233.0% 15 qtrs
10 WELLINGTON MANAGEMENT GROUP LLP 3.40M +150.1K (+4.6%) 42.62M +12.8M (+43.1%) 2.35% -0.150 pp 0.01% +0.002 pp USD9.14 +37.0% 4 qtrs
11 BIOIMPACT CAPITAL LLC 3.29M -119.9K (-3.5%) 41.15M +10.0M (+32.0%) 2.27% -0.348 pp 4.71% -0.394 pp USD3.97 +215.4% 8 qtrs
12 VIKING GLOBAL INVESTORS LP 3.20M -1.9M (-37.6%) 40.05M -6.9M (-14.7%) 2.20% -1.730 pp 0.11% -0.016 pp USD6.86 +82.5% 14 qtrs
13 ORBIMED ADVISORS LLC 3.19M -117.7K (-3.6%) 39.95M +9.7M (+32.0%) 2.20% -0.339 pp 0.82% +0.105 pp USD5.75 +117.7% 4 qtrs
14 ALLIANCEBERNSTEIN L.P. 3.08M -1.2M (-28.2%) 38.60M -676.9K (-1.7%) 2.12% -1.168 pp 0.01% 0.000 pp USD5.47 +128.9% 7 qtrs
15 OCTAGON CAPITAL ADVISORS LP 2.82M +— (+0.0%) 35.24M +9.5M (+36.8%) 1.94% -0.220 pp 4.28% +0.375 pp USD6.21 +101.6% 4 qtrs
16 EVENTIDE ASSET MANAGEMENT, LLC 2.62M +1.2M (+89.8%) 32.83M +20.2M (+159.8%) 1.81% +0.748 pp 0.51% +0.305 pp USD8.81 +42.1% 3 qtrs
17 STATE STREET CORP 2.44M +215.6K (+9.7%) 30.49M +10.2M (+50.1%) 1.68% -0.025 pp 0.00% +0.000 pp USD5.47 +128.9% 16 qtrs
18 GEODE CAPITAL MANAGEMENT, LLC 2.41M +192.0K (+8.6%) 30.21M +9.9M (+48.6%) 1.66% -0.041 pp 0.00% +0.001 pp USD5.35 +134.0% 27 qtrs
19 SIREN, L.L.C. 2.29M -250.0K (-9.9%) 28.63M +5.4M (+23.3%) 1.58% -0.370 pp 0.85% -0.054 pp USD4.49 +178.8% 5 qtrs
20 AFFINITY ASSET ADVISORS, LLC 2.15M -649.8K (-23.2%) 26.92M +1.3M (+5.1%) 1.48% -0.666 pp 1.53% -0.698 pp USD6.19 +102.3% 4 qtrs
21 ACORN CAPITAL ADVISORS, LLC 2.14M +— (+0.0%) 26.85M +7.2M (+36.8%) 1.48% -0.167 pp 9.10% -0.864 pp USD4.27 +193.2% 5 qtrs
22 ARTIA GLOBAL PARTNERS LP 2.01M +13.9K (+0.7%) 25.21M +6.9M (+37.8%) 1.39% -0.146 pp 4.02% +1.124 pp USD6.78 +84.7% 3 qtrs
23 EMERALD ADVISERS, LLC 1.89M +1.9M (+100.0%) 23.69M +23.7M (+100.0%) 1.30% +1.304 pp 0.73% +0.730 pp USD12.52 +0.0% 1 qtrs NEW
24 RAYMOND JAMES FINANCIAL INC 1.77M +355.9K (+25.2%) 22.12M +9.2M (+71.3%) 1.22% +0.135 pp 0.01% +0.003 pp USD7.81 +60.3% 5 qtrs
25 LOGOS GLOBAL MANAGEMENT LP 1.55M -650.0K (-29.5%) 19.41M -724.0K (-3.6%) 1.07% -0.620 pp 1.17% -0.632 pp USD7.30 +71.5% 8 qtrs
26 PICTET ASSET MANAGEMENT HOLDING SA 1.53M +1.5M (+13,507.0%) 19.18M +19.1M (+18,518.5%) 1.06% +1.047 pp 0.02% +0.019 pp USD12.50 +0.2% 2 qtrs
27 EMERALD MUTUAL FUND ADVISERS TRUST 1.27M +1.3M (+100.0%) 15.93M +15.9M (+100.0%) 0.88% +0.877 pp 0.78% +0.776 pp USD12.52 +0.0% 1 qtrs NEW
28 PIVOTAL BIOVENTURE PARTNERS INVESTMENT ADVISOR LLC 1.26M +— (+0.0%) 15.73M +4.2M (+36.8%) 0.87% -0.098 pp 6.08% -0.565 pp USD5.79 +116.2% 3 qtrs
29 FRONTIER CAPITAL MANAGEMENT CO LLC 1.11M +1.1M (+100.0%) 13.88M +13.9M (+100.0%) 0.76% +0.764 pp 0.15% +0.147 pp USD12.52 +0.0% 1 qtrs NEW
30 BANK OF AMERICA CORP /DE/ 1.09M -742.0K (-40.4%) 13.71M -3.1M (-18.4%) 0.75% -0.655 pp 0.00% 0.000 pp USD6.92 +80.9% 13 qtrs
31 GOLDMAN SACHS GROUP INC 1.06M +269.4K (+34.2%) 13.23M +6.0M (+83.6%) 0.73% +0.124 pp 0.00% +0.001 pp USD8.56 +46.3% 11 qtrs
32 FLPUTNAM INVESTMENT MANAGEMENT CO 1.05M +5.3K (+0.5%) 13.19M +3.6M (+37.5%) 0.73% -0.078 pp 0.19% +0.048 pp USD8.86 +41.3% 3 qtrs
33 MORGAN STANLEY 1.05M -3.3M (-75.6%) 13.15M -26.2M (-66.6%) 0.72% -2.576 pp 0.00% -0.002 pp USD8.21 +52.5% 16 qtrs
34 WOODLINE PARTNERS LP 1.00M +900.0K (+897.5%) 12.52M +11.6M (+1,264.8%) 0.69% +0.612 pp 0.05% +0.044 pp USD11.74 +6.6% 6 qtrs
35 POINT72 ASSET MANAGEMENT, L.P. 1.00M +58.1K (+6.2%) 12.52M +3.9M (+45.3%) 0.69% -0.034 pp 0.01% 0.000 pp USD4.61 +171.6% 5 qtrs
36 NAN FUNG TRINITY (HK) LTD 917.5K +827.9K (+924.2%) 11.49M +10.7M (+1,301.5%) 0.63% +0.564 pp 0.91% +0.828 pp USD12.19 +2.7% 2 qtrs
37 SOLEUS CAPITAL MANAGEMENT, L.P. 900.0K +875.0K (+3,500.0%) 11.27M +11.0M (+4,825.9%) 0.62% +0.601 pp 0.42% +0.404 pp USD12.32 +1.6% 3 qtrs
38 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 836.8K +30.5K (+3.8%) 10.48M +3.1M (+42.0%) 0.58% -0.042 pp 0.00% +0.001 pp USD7.75 +61.5% 15 qtrs
39 SUSQUEHANNA INTERNATIONAL GROUP, LLP 825.5K -775.2K (-48.4%) 10.34M -4.3M (-29.4%) 0.57% -0.659 pp 0.00% -0.001 pp USD8.89 +40.8% 6 qtrs
40 NORTHERN TRUST CORP 762.0K +25.0K (+3.4%) 9.54M +2.8M (+41.5%) 0.53% -0.040 pp 0.00% +0.000 pp USD4.94 +153.4% 27 qtrs
41 PANAGORA ASSET MANAGEMENT INC 693.0K +122.5K (+21.5%) 8.68M +3.5M (+66.2%) 0.48% +0.040 pp 0.03% +0.010 pp USD6.72 +86.3% 6 qtrs
42 SPHERA FUNDS MANAGEMENT LTD. 598.5K -45.4K (-7.1%) 7.49M +1.6M (+27.2%) 0.41% -0.082 pp 1.45% +0.206 pp USD5.47 +128.9% 3 qtrs
43 BARCLAYS PLC 582.7K +487.4K (+511.8%) 7.29M +7.0M (+2,193.4%) 0.40% +0.329 pp 0.00% +0.002 pp USD11.27 +11.1% 11 qtrs
44 MILLENNIUM MANAGEMENT LLC 570.2K -157.4K (-21.6%) 7.14M +481.7K (+7.2%) 0.39% -0.165 pp 0.00% +0.000 pp USD8.42 +48.7% 6 qtrs
45 PRUDENTIAL FINANCIAL INC 549.2K -53.4K (-8.9%) 6.88M +1.4M (+24.7%) 0.38% -0.084 pp 0.01% +0.002 pp USD7.77 +61.1% 3 qtrs
46 EAM INVESTORS, LLC 541.2K -8.2K (-1.5%) 6.78M +1.8M (+36.5%) 0.37% -0.049 pp 0.75% +0.186 pp USD6.62 +89.1% 4 qtrs
47 SILVERARC CAPITAL MANAGEMENT, LLC 541.2K -47.5K (-8.1%) 6.78M +1.4M (+25.8%) 0.37% -0.079 pp 0.94% +0.215 pp USD3.08 +306.5% 14 qtrs
48 BURKEHILL GLOBAL MANAGEMENT, LP 525.0K +— (+0.0%) 6.57M +1.8M (+36.8%) 0.36% -0.041 pp 0.43% +0.160 pp USD5.47 +128.9% 3 qtrs
49 PEREGRINE CAPITAL MANAGEMENT LLC 507.7K -112.8K (-18.2%) 6.36M +679.0K (+12.0%) 0.35% -0.126 pp 0.19% +0.024 pp USD9.15 +36.8% 2 qtrs
50 INVESCO LTD. 498.9K +15.9K (+3.3%) 6.25M +1.8M (+41.3%) 0.34% -0.027 pp 0.00% +0.000 pp USD7.34 +70.6% 11 qtrs
51 J. GOLDMAN & CO LP 444.4K -348.4K (-44.0%) 5.56M -1.7M (-23.3%) 0.31% -0.302 pp 0.15% -0.036 pp USD5.11 +145.0% 15 qtrs
52 STEMPOINT CAPITAL LP 399.6K +48.8K (+13.9%) 5.00M +1.8M (+55.9%) 0.28% +0.006 pp 0.86% +0.215 pp USD9.56 +31.0% 2 qtrs
53 OPALEYE MANAGEMENT INC. 345.1K -44.9K (-11.5%) 4.32M +752.2K (+21.1%) 0.24% -0.061 pp 0.57% +0.066 pp USD1.94 +545.4% 13 qtrs
54 AMERIPRISE FINANCIAL INC 324.2K +324.2K (+100.0%) 4.06M +4.1M (+100.0%) 0.22% +0.223 pp 0.00% +0.001 pp USD12.52 +0.0% 8 qtrs
55 UBS GROUP AG 274.6K -24.0K (-8.0%) 3.44M +706.0K (+25.8%) 0.19% -0.040 pp 0.00% +0.000 pp USD5.30 +136.2% 20 qtrs
56 BANK OF NEW YORK MELLON CORP 260.6K +34.2K (+15.1%) 3.26M +1.2M (+57.5%) 0.18% +0.006 pp 0.00% +0.000 pp USD5.73 +118.5% 14 qtrs
57 F/M INVESTMENTS LLC 241.5K +241.5K (+100.0%) 3.02M +3.0M (+100.0%) 0.17% +0.166 pp 0.11% +0.115 pp USD12.52 +0.0% 1 qtrs NEW
58 VOYA INVESTMENT MANAGEMENT LLC 226.2K +211.0K (+1,390.2%) 2.83M +2.7M (+1,939.1%) 0.16% +0.144 pp 0.00% +0.003 pp USD11.90 +5.2% 11 qtrs
59 VELAN CAPITAL INVESTMENT MANAGEMENT LP 205.0K +— (+0.0%) 2.57M +690.9K (+36.8%) 0.14% -0.016 pp 1.49% -0.273 pp USD9.15 +36.8% 2 qtrs
60 NUVEEN, LLC 183.3K +— (+0.0%) 2.30M +617.8K (+36.8%) 0.13% -0.014 pp 0.00% +0.000 pp USD6.51 +92.3% 4 qtrs
61 BALYASNY ASSET MANAGEMENT L.P. 174.6K -451.8K (-72.1%) 2.19M -3.5M (-61.9%) 0.12% -0.360 pp 0.00% -0.005 pp USD6.08 +105.9% 4 qtrs
62 SWISS NATIONAL BANK 168.2K +6.5K (+4.0%) 2.11M +626.3K (+42.3%) 0.12% -0.008 pp 0.00% +0.000 pp USD9.28 +34.9% 2 qtrs
63 FRED ALGER MANAGEMENT, LLC 158.0K -33.1K (-17.3%) 1.98M +229.8K (+13.1%) 0.11% -0.038 pp 0.01% +0.001 pp USD8.26 +51.6% 6 qtrs
64 SUPERSTRING CAPITAL MANAGEMENT LP 148.3K +148.3K (+100.0%) 1.86M +1.9M (+100.0%) 0.10% +0.102 pp 0.99% +0.994 pp USD12.52 +0.0% 1 qtrs NEW
65 SEI INVESTMENTS CO 147.9K +62.1K (+72.4%) 1.85M +1.1M (+135.9%) 0.10% +0.036 pp 0.00% +0.001 pp USD10.57 +18.4% 2 qtrs
66 D. E. SHAW & CO., INC. 141.3K +141.3K (+100.0%) 1.77M +1.8M (+100.0%) 0.10% +0.097 pp 0.00% +0.001 pp USD12.52 +0.0% 1 qtrs NEW
67 UBS ASSET MANAGEMENT AMERICAS INC 140.7K +24.3K (+20.8%) 1.76M +696.2K (+65.3%) 0.10% +0.008 pp 0.00% +0.000 pp USD9.73 +28.7% 2 qtrs
68 BIT CAPITAL GMBH 130.0K +123.3K (+1,829.1%) 1.63M +1.6M (+2,539.6%) 0.09% +0.084 pp 0.06% +0.058 pp USD12.23 +2.4% 4 qtrs
69 HRT FINANCIAL LP 125.1K +125.1K (+100.0%) 1.57M +1.6M (+100.0%) 0.09% +0.086 pp 0.00% +0.005 pp USD12.52 +0.0% 1 qtrs NEW
70 SG AMERICAS SECURITIES, LLC 124.6K +60.0K (+93.0%) 1.56M +969.0K (+164.0%) 0.09% +0.036 pp 0.00% +0.000 pp USD10.77 +16.2% 10 qtrs
71 CITIGROUP INC 123.5K +96.6K (+358.9%) 1.55M +1.3M (+527.9%) 0.09% +0.065 pp 0.00% +0.001 pp USD10.61 +18.0% 11 qtrs
72 STATE OF WISCONSIN INVESTMENT BOARD 120.6K -2.7K (-2.2%) 1.51M +381.5K (+33.8%) 0.08% -0.012 pp 0.00% +0.001 pp USD5.67 +120.8% 5 qtrs
73 HIGHVISTA STRATEGIES LLC 106.2K +106.2K (+100.0%) 1.33M +1.3M (+100.0%) 0.07% +0.073 pp 0.34% +0.342 pp USD12.52 +0.0% 1 qtrs NEW
74 RHUMBLINE ADVISERS 105.9K -9.1K (-7.9%) 1.33M +273.7K (+26.0%) 0.07% -0.015 pp 0.00% +0.000 pp USD3.83 +226.9% 11 qtrs
75 WELLS FARGO & COMPANY/MN 101.3K +45.6K (+81.9%) 1.27M +758.5K (+148.9%) 0.07% +0.027 pp 0.00% +0.000 pp USD8.44 +48.3% 13 qtrs
76 OPPENHEIMER & CO INC 100.7K +2.0K (+2.1%) 1.26M +357.9K (+39.6%) 0.07% -0.006 pp 0.02% +0.007 pp USD4.08 +206.9% 8 qtrs
77 LMR PARTNERS LLP 100.0K +— (+0.0%) 1.25M +337.0K (+36.8%) 0.07% -0.008 pp 0.00% -0.002 pp USD6.29 +99.0% 4 qtrs
78 ROSALIND ADVISORS, INC. 100.0K +— (+0.0%) 1.25M +337.0K (+36.8%) 0.07% -0.008 pp 0.44% +0.127 pp USD2.52 +396.8% 9 qtrs
79 DIADEMA PARTNERS LP 97.2K +11.4K (+13.2%) 1.22M +431.4K (+54.9%) 0.07% +0.001 pp 0.21% +0.009 pp USD7.00 +78.9% 4 qtrs
80 ERSTE ASSET MANAGEMENT GMBH 90.0K +90.0K (+100.0%) 1.15M +1.2M (+100.0%) 0.06% +0.062 pp 0.01% +0.010 pp USD12.52 +0.0% 1 qtrs NEW
81 CITADEL ADVISORS LLC 90.0K -142.0K (-61.2%) 1.13M -996.0K (-46.9%) 0.06% -0.116 pp 0.00% 0.000 pp USD7.62 +64.3% 9 qtrs
82 SECTORAL ASSET MANAGEMENT INC 84.3K -21.7K (-20.5%) 1.05M +85.4K (+8.8%) 0.06% -0.023 pp 0.85% +0.247 pp USD5.97 +109.7% 4 qtrs
83 XTX TOPCO LTD 83.8K +83.8K (+100.0%) 1.05M +1.0M (+100.0%) 0.06% +0.058 pp 0.03% +0.028 pp USD12.52 +0.0% 5 qtrs
84 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 83.8K +2.1K (+2.6%) 1.05M +301.5K (+40.3%) 0.06% -0.005 pp 0.00% +0.000 pp USD8.88 +41.0% 11 qtrs
85 TWO SIGMA INVESTMENTS, LP 83.8K -36.2K (-30.2%) 1.05M -48.7K (-4.4%) 0.06% -0.034 pp 0.00% 0.000 pp USD4.15 +201.7% 5 qtrs
86 COMERICA BANK 83.0K +82.6K (+19,481.8%) 1.04M +1.0M (+26,691.2%) 0.06% +0.057 pp 0.00% +0.004 pp USD12.48 +0.3% 3 qtrs
87 WEXFORD CAPITAL LP 82.0K +82.0K (+100.0%) 1.03M +1.0M (+100.0%) 0.06% +0.057 pp 0.20% +0.198 pp USD12.52 +0.0% 1 qtrs NEW
88 LEGAL & GENERAL GROUP PLC 81.7K -299.0 (-0.4%) 1.02M +272.5K (+36.3%) 0.06% -0.007 pp 0.00% +0.000 pp USD8.55 +46.4% 11 qtrs
89 PFS PARTNERS, LLC 79.0K +— (+0.0%) 989.1K +266.2K (+36.8%) 0.05% -0.006 pp 0.45% +0.109 pp USD2.39 +423.8% 11 qtrs
90 MAI CAPITAL MANAGEMENT 77.8K -20.7K (-21.0%) 973.7K +72.5K (+8.0%) 0.05% -0.022 pp 0.01% +0.000 pp USD2.55 +391.0% 16 qtrs
91 HUDSON BAY CAPITAL MANAGEMENT LP 75.0K +75.0K (+100.0%) 939.0K +939.0K (+100.0%) 0.05% +0.052 pp 0.00% +0.003 pp USD12.52 +0.0% 1 qtrs NEW
92 CAMPBELL & CO INVESTMENT ADVISER LLC 71.1K +46.2K (+185.7%) 890.1K +662.4K (+290.9%) 0.05% +0.030 pp 0.04% +0.026 pp USD10.63 +17.8% 3 qtrs
93 DEUTSCHE BANK AG\ 70.8K +19.2K (+37.2%) 886.8K +414.3K (+87.7%) 0.05% +0.009 pp 0.00% +0.000 pp USD7.04 +77.8% 10 qtrs
94 JANE STREET GROUP, LLC 69.1K -133.5K (-65.9%) 865.1K -988.7K (-53.3%) 0.05% -0.108 pp 0.00% 0.000 pp USD7.52 +66.5% 3 qtrs
95 TUDOR INVESTMENT CORP ET AL 68.5K +68.5K (+100.0%) 857.4K +857.4K (+100.0%) 0.05% +0.047 pp 0.00% +0.002 pp USD12.52 +0.0% 1 qtrs NEW
96 WEALTHTRUST AXIOM LLC 61.5K +— (+0.0%) 770.0K +207.3K (+36.8%) 0.04% -0.005 pp 0.20% +0.047 pp USD2.37 +428.3% 21 qtrs
Ownership breakdown by holder

Insider Activity

Insider Activity — Latest Quarter
Ratio by transactions
0.00
Bearish
Buys
6
Sells
0
Shares acquired
1.55M
Shares disposed
Cash buys
Cash sales
Net activity
+1,545,000
Insider buys vs sells (history) From To
Recent insider transactions From To
Date Person Role Transaction A/D Security Shares Price Value Owned after D/I Filing
2026-02-19 Simon Farrell Officer A-Award A Stock Option (right to buy) 160,000 10.56 1.69M 160,000 D
2026-02-19 SCIASCIA THOMAS Officer A-Award A Stock Option (right to buy) 85,000 10.56 897.6K 85,000 D
2026-02-19 Galletta Christopher Officer A-Award A Stock Option (right to buy) 35,000 10.56 369.6K 35,000 D
2026-02-19 GOOD JENNIFER L Director / Officer A-Award A Stock Option (right to buy) 675,000 10.56 7.13M 675,000 D
2026-02-19 Cassella James V Officer A-Award A Stock Option (right to buy) 215,000 10.56 2.27M 215,000 D
2026-01-08 HASTINGS DAVID C 0 0.00 0
2025-12-31 Walker Paul Edward 10% Owner Common Stock 0 0.00 948,948 I
2025-12-31 SANDELL SCOTT D 10% Owner Common Stock 0 0.00 948,948 I
2025-12-31 Makhzoumi Mohamad 10% Owner Common Stock 0 0.00 948,948 I
2025-12-31 Florence Anthony A. Jr. 10% Owner Common Stock 0 0.00 948,948 I
2025-12-31 Chang Carmen 10% Owner Common Stock 0 0.00 948,948 I
2025-12-31 Behbahani Ali 10% Owner Common Stock 0 0.00 948,948 I
2025-12-02 Galletta Christopher Officer M-Exempt A Common Stock 4,225 0.51 2.2K 26,095 D
2025-06-11 VANLENT ANNE Director A-Award A Nonstatutory Stock Option (right to buy) 45,000 6.25 281.3K 45,000 D
2025-06-11 Meeker David P Director A-Award A Nonstatutory Stock Option (right to buy) 45,000 6.25 281.3K 45,000 D
2025-06-11 Mathers Edward T Director A-Award A Nonstatutory Stock Option (right to buy) 45,000 6.25 281.3K 45,000 D
2025-06-11 Heffernan Michael Thomas Director A-Award A Nonstatutory Stock Option (right to buy) 45,000 6.25 281.3K 45,000 D
2025-06-11 Colangelo Dominick Director A-Award A Nonstatutory Stock Option (right to buy) 45,000 6.25 281.3K 45,000 D
2025-05-31 Simon Farrell Officer A-Award A Performance Stock Option (right to buy) 72,000 2.38 171.4K 110,400 D
2025-05-31 SCIASCIA THOMAS Officer A-Award A Performance Stock Option (right to buy) 60,000 2.38 142.8K 92,000 D
2025-05-31 Galletta Christopher Officer A-Award A Performance Stock Option (right to buy) 8,550 2.38 20.3K 13,110 D
2025-05-31 GOOD JENNIFER L Director / Officer A-Award A Performance Stock Option (right to buy) 102,000 2.38 242.8K 156,400 D
2025-05-31 Delfini Lisa Officer A-Award A Performance Stock Option (right to buy) 72,000 2.38 171.4K 110,400 D
2025-04-17 Walker Paul Edward 10% Owner X-InTheMoney D 3.5-Year Common Stock Warrant 1,851,852 1.37 2.54M 0 I
2025-04-17 SANDELL SCOTT D 10% Owner X-InTheMoney D 3.5-Year Common Stock Warrant 1,851,852 1.37 2.54M 0 I
2025-04-17 New Enterprise Associates 16, L.P. 10% Owner X-InTheMoney D 3.5-Year Common Stock Warrant 1,851,852 1.37 2.54M 0 D
2025-04-17 Makhzoumi Mohamad 10% Owner X-InTheMoney D 3.5-Year Common Stock Warrant 1,851,852 1.37 2.54M 0 I
2025-04-17 Florence Anthony A. Jr. 10% Owner X-InTheMoney D 3.5-Year Common Stock Warrant 1,851,852 1.37 2.54M 0 I
2025-04-17 Chang Carmen 10% Owner X-InTheMoney D 3.5-Year Common Stock Warrant 1,851,852 1.37 2.54M 0 I
2025-04-17 Behbahani Ali 10% Owner X-InTheMoney D 3.5-Year Common Stock Warrant 1,851,852 1.37 2.54M 0 I
2025-04-17 BASKETT FOREST 10% Owner X-InTheMoney D 3.5-Year Common Stock Warrant 1,851,852 1.37 2.54M 0 I
2025-03-25 SCIASCIA THOMAS Officer M-Exempt D Stock Option (right to buy) 2,631 1.43 3.8K 0 D
2025-03-21 GOOD JENNIFER L Director / Officer M-Exempt A Common Stock 5,263 1.43 7.5K 218,576 D
2025-03-10 Simon Farrell Officer S-Sale D Common Stock 76,963 6.73 517.8K 81,250 D
2025-03-10 SCIASCIA THOMAS Officer A-Award A Performance Stock Option (right to buy) 32,000 2.38 76.2K 32,000 D
2025-03-10 Galletta Christopher Officer A-Award A Performance Stock Option (right to buy) 4,560 2.38 10.9K 4,560 D
2025-03-10 GOOD JENNIFER L Director / Officer A-Award A Performance Stock Option (right to buy) 54,400 2.38 129.5K 54,400 D
2025-03-10 Delfini Lisa Officer A-Award A Performance Stock Option (right to buy) 38,400 2.38 91.4K 38,400 D
2025-02-18 Simon Farrell Officer A-Award A Stock Option (right to buy) 225,500 4.22 951.6K 225,500 D
2025-02-18 SCIASCIA THOMAS Officer A-Award A Stock Option (right to buy) 116,000 4.22 489.5K 116,000 D
2025-02-18 Galletta Christopher Officer A-Award A Stock Option (right to buy) 41,000 4.22 173.0K 41,000 D
2025-02-18 GOOD JENNIFER L Director / Officer A-Award A Stock Option (right to buy) 811,000 4.22 3.42M 811,000 D
2025-02-18 Delfini Lisa Officer A-Award A Stock Option (right to buy) 225,500 4.22 951.6K 225,500 D
2025-02-18 Cassella James V Officer A-Award A Stock Option (right to buy) 257,500 4.22 1.09M 257,500 D
2025-01-08 Delfini Lisa Officer M-Exempt A Common Stock 5,000 0.51 2.6K 64,660 D
2025-01-07 Delfini Lisa Officer M-Exempt A Common Stock 1,000 0.51 511.00 59,660 D
2024-12-13 Galletta Christopher Officer M-Exempt D Stock Option (right to buy) 15,000 0.51 7.7K 20,000 D
2024-09-30 Cassella James V Officer A-Award A Stock Option (right to buy) 400,000 3.34 1.34M 400,000 D
2024-09-09 GOOD JENNIFER L Director / Officer M-Exempt A Common Stock 1,840 1.43 2.6K 215,153
2024-09-06 GOOD JENNIFER L Director / Officer M-Exempt A Common Stock 4,219 1.43 6.0K 217,532
2024-09-05 GOOD JENNIFER L Director / Officer M-Exempt D Stock Option (right to buy) 40,277 1.43 57.6K 6,059
2024-09-04 GOOD JENNIFER L Director / Officer S-Sale D Common Stock 10,981 3.02 33.2K 213,313
2024-09-03 GOOD JENNIFER L Director / Officer M-Exempt A Common Stock 3,863 1.43 5.5K 217,176
2024-08-27 Meeker David P Director S-Sale D Common Stock 4,555 2.93 13.4K 352,489
2024-08-19 SCIASCIA THOMAS Officer M-Exempt A Common Stock 16,496 1.43 23.6K 236,811
2024-08-16 SCIASCIA THOMAS Officer S-Sale D Common Stock 18,660 2.76 51.4K 220,315
2024-08-15 SCIASCIA THOMAS Officer M-Exempt A Common Stock 12,745 1.43 18.2K 233,060
2024-08-14 SCIASCIA THOMAS Officer M-Exempt A Common Stock 100 1.43 143.00 220,415
2024-06-13 Meeker David P Director A-Award A Nonstatutory Stock Option (right to buy) 30,000 2.77 83.1K 30,000
2024-06-13 Mathers Edward T Director A-Award A Nonstatutory Stock Option (right to buy) 30,000 2.77 83.1K 30,000
2024-06-13 Heffernan Michael Thomas Director A-Award A Nonstatutory Stock Option (right to buy) 30,000 2.77 83.1K 30,000
2024-06-13 Colangelo Dominick Director A-Award A Nonstatutory Stock Option (right to buy) 30,000 2.77 83.1K 30,000
2024-06-13 Cassella James V Director A-Award A Nonstatutory Stock Option (right to buy) 30,000 2.77 83.1K 30,000
2024-05-29 SCIASCIA THOMAS Officer M-Exempt A Common Stock 59,354 2.19 130.0K 267,801
2024-05-22 Delfini Lisa Officer M-Exempt A Common Stock 16,043 0.51 8.2K 57,629
2024-05-20 GOOD JENNIFER L Director / Officer M-Exempt A Common Stock 25,037 2.19 54.8K 238,350
2024-05-10 GOOD JENNIFER L Director / Officer M-Exempt D Stock Option (right to buy) 4,578 2.19 10.0K 58,226
2024-02-15 Simon Farrell Officer A-Award A Stock Option (right to buy) 175,000 2.38 416.5K 175,000
2024-02-15 SCIASCIA THOMAS Officer A-Award A Stock Option (right to buy) 150,000 2.38 357.0K 150,000
2024-02-15 Galletta Christopher Officer A-Award A Stock Option (right to buy) 28,500 2.38 67.8K 28,500
2024-02-15 GOOD JENNIFER L Director / Officer A-Award A Stock Option (right to buy) 630,000 2.38 1.50M 630,000
2024-02-15 Delfini Lisa Officer A-Award A Stock Option (right to buy) 175,000 2.38 416.5K 175,000
2024-02-15 Clark David J Officer A-Award A Stock Option (right to buy) 175,000 2.38 416.5K 175,000
2023-10-11 Delfini Lisa Officer M-Exempt D Stock Option (right to buy) 2,292 0.51 1.2K 64,168
2023-09-11 Delfini Lisa Officer M-Exempt D Stock Option (right to buy) 2,291 0.51 1.2K 66,460
2023-08-11 Delfini Lisa Officer M-Exempt A Common Stock 2,292 0.51 1.2K 33,496
2023-07-11 Delfini Lisa Officer M-Exempt A Common Stock 2,292 0.51 1.2K 31,891
2023-06-28 VANLENT ANNE Director A-Award A Nonstatutory Stock Option (right to buy) 30,000 2.27 68.1K 30,000
2023-06-28 Meeker David P Director A-Award A Nonstatutory Stock Option (right to buy) 30,000 2.27 68.1K 30,000
2023-06-28 Mathers Edward T Director A-Award A Nonstatutory Stock Option (right to buy) 30,000 2.27 68.1K 30,000
2023-06-28 Heffernan Michael Thomas Director A-Award A Nonstatutory Stock Option (right to buy) 30,000 2.27 68.1K 30,000
2023-06-28 Colangelo Dominick Director A-Award A Nonstatutory Stock Option (right to buy) 30,000 2.27 68.1K 30,000
2023-06-28 Cassella James V Director A-Award A Nonstatutory Stock Option (right to buy) 30,000 2.27 68.1K 30,000
2023-06-20 Simon Farrell Officer M-Exempt D Stock Option (right to buy) 6,250 0.51 3.2K 50,000
2023-06-12 Delfini Lisa Officer M-Exempt D Stock Option (right to buy) 2,291 0.51 1.2K 73,335
2023-05-11 Delfini Lisa Officer M-Exempt A Common Stock 2,291 0.51 1.2K 28,480
2023-04-11 Delfini Lisa Officer M-Exempt D Stock Option (right to buy) 2,292 0.51 1.2K 77,917
2023-03-13 Delfini Lisa Officer M-Exempt D Stock Option (right to buy) 2,291 0.51 1.2K 80,209
2023-03-07 Simon Farrell Officer M-Exempt D Stock Option (right to buy) 18,750 0.51 9.6K 56,250
2023-02-16 Simon Farrell Officer D Stock Option (right to buy) 75,000 3.91 293.3K 0
2023-02-16 SCIASCIA THOMAS Officer A-Award A Stock Option (right to buy) 187,500 2.67 500.6K 187,500
2023-02-16 Galletta Christopher Officer A-Award A Stock Option (right to buy) 40,000 2.67 106.8K 40,000
2023-02-16 GOOD JENNIFER L Director / Officer A-Award A Stock Option (right to buy) 375,000 2.67 1.00M 375,000
2023-02-16 Delfini Lisa Officer A-Award A Stock Option (right to buy) 187,500 2.67 500.6K 187,500
2023-02-13 Delfini Lisa Officer M-Exempt D Stock Option (right to buy) 27,500 0.51 14.1K 82,500
2022-11-14 Clark David J Officer A-Award A Stock Option (right to buy) 300,000 0.00 300,000
2022-09-19 SCIASCIA THOMAS Officer A-Award A Performance Stock Options (right to buy) 7,500 3.21 24.1K 37,500
2022-09-19 GOOD JENNIFER L Director / Officer A-Award A Performance Stock Options (right to buy) 32,000 3.21 102.7K 160,000
2022-07-05 TPG GP A, LLC 10% Owner S-Sale D Common Stock 63,569 3.11 197.8K 3,824,883
2022-07-01 WINKELRIED JON Director S-Sale D Common Stock 63,569 3.11 197.8K 3,824,883
2022-07-01 TPG GP A, LLC 10% Owner S-Sale D Common Stock 436,431 2.86 1.25M 3,888,452
2022-06-30 TPG GP A, LLC 10% Owner S-Sale D Common Stock 429,838 2.77 1.19M 4,324,883
2022-06-29 WINKELRIED JON Director S-Sale D Common Stock 46,128 2.74 126.3K 4,754,721
2022-06-29 TPG GP A, LLC 10% Owner S-Sale D Common Stock 46,128 2.74 126.3K 4,754,721
2022-06-29 SCIASCIA THOMAS Officer A-Award A Performance Stock Options (right to buy) 30,000 0.00 30,000
2022-06-29 GOOD JENNIFER L Director / Officer A-Award A Performance Stock Options (right to buy) 128,000 3.21 410.9K 128,000
2022-06-29 Forbes William P Officer A-Award A Performance Stock Options (right to buy) 48,000 3.21 154.1K 48,000
2022-06-23 VANLENT ANNE Director A-Award A Nonstatutory Stock Option (right to buy) 20,000 0.00 20,000
2022-06-23 Meeker David P Director A-Award A Nonstatutory Stock Option (right to buy) 20,000 0.00 20,000
2022-06-23 Mathers Edward T Director A-Award A Nonstatutory Stock Option (right to buy) 20,000 0.00 20,000
2022-06-23 Heffernan Michael Thomas Director A-Award A Nonstatutory Stock Option (right to buy) 20,000 2.27 45.4K 20,000
2022-06-23 Colangelo Dominick Director A-Award A Nonstatutory Stock Option (right to buy) 20,000 2.27 45.4K 20,000
2022-06-23 Cassella James V Director A-Award A Nonstatutory Stock Option (right to buy) 20,000 0.00 20,000
2022-05-02 WINKELRIED JON Director S-Sale D Common Stock 600 2.70 1.6K 4,800,849
2022-05-02 TPG GP A, LLC 10% Owner S-Sale D Common Stock 600 2.70 1.6K 4,800,849
2022-04-29 TPG GP A, LLC 10% Owner S-Sale D Common Stock 16,163 2.75 44.4K 4,801,449
2022-04-28 WINKELRIED JON Director S-Sale D Common Stock 16,163 2.75 44.4K 4,801,449
2022-04-28 TPG GP A, LLC 10% Owner S-Sale D Common Stock 7,271 2.77 20.1K 4,817,612
2022-04-11 Walker Paul Edward Director P-Purchase A Pre-Funded Warrants 3,000,000 1.90 5.70M 3,000,000
2022-04-11 Sonsini Peter W. Director P-Purchase A Common Stock 948,948 1.90 1.80M 948,948
2022-04-11 SANDELL SCOTT D 10% Owner P-Purchase A Common Stock 948,948 1.90 1.80M 948,948
2022-04-11 New Enterprise Associates 16, L.P. 10% Owner P-Purchase A Common Stock 2,631,578 1.90 5.00M 10,421,428
2022-04-11 NEA 16 GP, LLC Director P-Purchase A Common Stock 2,631,578 1.90 5.00M 10,421,428
2022-04-11 Mathers Edward T Director A-Award A Common Stock 948,948 1.90 1.80M 948,948
2022-04-11 Makhzoumi Mohamad 10% Owner P-Purchase A Pre-Funded Warrants 3,000,000 0.00 3.0K 3,000,000
2022-04-11 Florence Anthony A. Jr. Director P-Purchase A Common Stock 948,948 1.90 1.80M 948,948
2022-04-11 Chang Carmen 10% Owner P-Purchase A Common Stock 2,631,578 1.90 5.00M 10,421,428
2022-04-11 Behbahani Ali 10% Owner P-Purchase A Common Stock 2,631,578 1.90 5.00M 10,421,428
2022-04-11 BASKETT FOREST Director P-Purchase A Common Stock 2,631,578 1.90 5.00M 10,421,428
2022-02-14 GOOD JENNIFER L Director / Officer A-Award A Stock Option (right to buy) 275,000 0.51 139.5K 275,000
2022-02-11 SCIASCIA THOMAS Officer A-Award A Stock Option (right to buy) 110,000 0.51 56.2K 110,000
2022-02-11 Galletta Christopher Officer A-Award A Stock Option (right to buy) 35,000 0.51 17.9K 35,000
2022-02-11 Forbes William P Officer A-Award A Stock Option (right to buy) 137,500 0.51 70.3K 137,500
2022-02-11 Delfini Lisa Officer A-Award A Stock Option (right to buy) 110,000 0.51 56.2K 110,000
2022-01-12 TPG GP A, LLC 10% Owner I Common Stock 0 0.00 4,824,883
2021-10-18 Walker Paul Edward 10% Owner P-Purchase A Common Stock 1,851,852 1.62 3.00M 7,789,850
2021-10-18 Sonsini Peter W. 10% Owner P-Purchase A Common Stock 1,851,852 1.62 3.00M 7,789,850
2021-10-18 SANDELL SCOTT D 10% Owner P-Purchase A Common Stock 1,851,852 1.62 3.00M 7,789,850
2021-10-18 New Enterprise Associates 16, L.P. 10% Owner P-Purchase A 3.5-Year Common Stock Warrant 1,851,852 1.37 2.54M 1,851,852
2021-10-18 Makhzoumi Mohamad 10% Owner P-Purchase A Common Stock 1,851,852 1.62 3.00M 7,789,850
2021-10-18 Florence Anthony A. Jr. 10% Owner P-Purchase A 7-Year Common Stock Warrant 1,851,852 1.37 2.54M 1,851,852
2021-10-18 Chang Carmen 10% Owner P-Purchase A 3.5-Year Common Stock Warrant 1,851,852 1.37 2.54M 1,851,852
2021-10-18 Behbahani Ali 10% Owner P-Purchase A 7-Year Common Stock Warrant 1,851,852 1.37 2.54M 1,851,852
2021-10-18 BASKETT FOREST 10% Owner P-Purchase A 7-Year Common Stock Warrant 1,851,852 1.37 2.54M 1,851,852
2021-08-09 Delfini Lisa Officer A-Award A Stock Option (right to buy) 100,000 1.97 197.0K 100,000
2021-06-16 VANLENT ANNE Director A-Award A Nonstatutory Stock Option (right to buy) 20,000 2.25 45.0K 20,000
2021-06-16 Meeker David P Director A-Award A Nonstatutory Stock Option (right to buy) 20,000 2.25 45.0K 20,000
2021-06-16 Mathers Edward T Director A-Award A Nonstatutory Stock Option (right to buy) 20,000 2.25 45.0K 20,000
2021-06-16 Heffernan Michael Thomas Director A-Award A Nonstatutory Stock Option (right to buy) 20,000 2.25 45.0K 20,000
2021-06-16 Colangelo Dominick Director A-Award A Nonstatutory Stock Option (right to buy) 20,000 2.25 45.0K 20,000
2021-06-16 Cassella James V Director A-Award A Nonstatutory Stock Option (right to buy) 20,000 2.25 45.0K 20,000
2021-04-13 Galletta Christopher Officer A-Award A Stock Option (right to buy) 25,000 2.53 63.3K 25,000
2021-04-12 Galletta Christopher Officer 0 0.00 0
2021-02-17 Seiter Christopher Officer A-Award A Stock Option (right to buy) 80,000 3.21 256.8K 80,000
2021-02-17 SCIASCIA THOMAS Officer A-Award A Stock Option (right to buy) 50,000 3.21 160.5K 50,000
2021-02-17 Muscolo Frank P Officer A-Award A Stock Option (right to buy) 30,000 3.21 96.3K 30,000
2021-02-17 GOOD JENNIFER L Director / Officer A-Award A Stock Option (right to buy) 160,000 3.21 513.6K 160,000
2021-02-01 Forbes William P Officer 0 0.00 0
2020-06-29 Colangelo Dominick Director A-Award A Nonstatutory Stock Option (right to buy) 23,684 6.87 162.7K 23,684
2020-06-11 VANLENT ANNE Director A-Award A Nonstatutory Stock Option (right to buy) 14,210 4.10 58.3K 14,210
2020-06-11 Meeker David P Director A-Award A Nonstatutory Stock Option (right to buy) 14,210 4.10 58.3K 14,210
2020-06-11 Mathers Edward T Director A-Award A Nonstatutory Stock Option (right to buy) 14,210 4.10 58.3K 14,210
2020-06-11 Heffernan Michael Thomas Director A-Award A Nonstatutory Stock Option (right to buy) 14,210 4.10 58.3K 14,210
2020-04-03 Walker Paul Edward 10% Owner X-InTheMoney A Common Stock 1,500,000 0.00 1.5K 5,938,562
2020-04-03 TPG Group Holdings (SBS) Advisors, Inc. 10% Owner X-InTheMoney D Call Option (obligation to sell) 1 0.00 0
2020-04-03 Sonsini Peter W. 10% Owner X-InTheMoney A Common Stock 1,500,000 0.00 1.5K 5,938,562
2020-04-03 SANDELL SCOTT D 10% Owner S-Sale D Common Stock 564 2.66 1.5K 5,937,998
2020-04-03 New Enterprise Associates 16, L.P. 10% Owner X-InTheMoney A Common Stock 1,500,000 0.00 1.5K 5,938,562
2020-04-03 Makhzoumi Mohamad 10% Owner X-InTheMoney D Call Option (right to buy) 1,500,000 0.00 1.5K 0
2020-04-03 MAKOWER JOSHUA 10% Owner S-Sale D Common Stock 564 2.66 1.5K 5,937,998
2020-04-03 Florence Anthony A. Jr. 10% Owner S-Sale D Common Stock 564 2.66 1.5K 5,937,998
2020-04-03 Chang Carmen 10% Owner X-InTheMoney A Common Stock 1,500,000 0.00 1.5K 5,938,562
2020-04-03 Behbahani Ali 10% Owner S-Sale D Common Stock 564 2.66 1.5K 5,937,998
2020-04-03 BASKETT FOREST 10% Owner X-InTheMoney A Common Stock 1,500,000 0.00 1.5K 5,938,562
2020-02-13 Seiter Christopher Officer A-Award A Stock Option (right to buy) 65,000 5.50 357.5K 65,000
2020-02-13 SCIASCIA THOMAS Officer A-Award A Stock Option (right to buy) 60,000 5.50 330.0K 60,000
2020-02-13 Muscolo Frank P Officer A-Award A Stock Option (right to buy) 15,000 5.50 82.5K 15,000
2020-02-13 Mazabraud Yann Officer A-Award A Stock Option (right to buy) 70,000 5.50 385.0K 70,000
2020-02-13 GOOD JENNIFER L Director / Officer A-Award A Stock Option (right to buy) 200,000 5.50 1.10M 200,000
2020-02-13 Cassella James V Director 0 0.00 0
2020-02-13 Brett-Smith Helena Officer A-Award A Stock Option (right to buy) 30,000 5.50 165.0K 30,000
2019-06-03 Seiter Christopher Officer A-Award A Stock Option (right to buy) 50,000 10.12 506.0K 50,000
2019-06-03 SCIASCIA THOMAS Officer A-Award A Stock Option (right to buy) 50,000 10.12 506.0K 50,000
2019-06-03 Muscolo Frank P Officer A-Award A Stock Option (right to buy) 15,000 10.12 151.8K 15,000
2019-06-03 Mazabraud Yann Officer A-Award A Stock Option (right to buy) 50,000 10.12 506.0K 50,000
2019-06-03 GOOD JENNIFER L Director / Officer A-Award A Stock Option (right to buy) 310,000 10.12 3.14M 310,000
2019-06-01 TPG Group Holdings (SBS) Advisors, Inc. 10% Owner X-InTheMoney D Common Stock 200,000 0.00 200.00 6,324,319
2019-05-09 Walker Paul Edward 10% Owner C-Conversion D Series C Preferred Stock 17,099,315 0.00 0
2019-05-09 VANLENT ANNE Director C-Conversion D Series C Preferred Stock 47,807 0.00 0
2019-05-09 TPG Group Holdings (SBS) Advisors, Inc. 10% Owner C-Conversion D Series B Preferred Stock 21,739,130 0.00 0
2019-05-09 Sonsini Peter W. 10% Owner P-Purchase A Common Stock 1,000,000 10.00 10.00M 2,938,562
2019-05-09 SCIASCIA THOMAS Officer / 10% Owner C-Conversion D Series C Preferred Stock 13,410 0.00 0
2019-05-09 SANDELL SCOTT D 10% Owner C-Conversion D Series C Preferred Stock 17,099,315 0.00 0
2019-05-09 Richard King Mellon Foundation 10% Owner C-Conversion D Series C Preferred Stock 1,908,450 0.00 0
2019-05-09 Omega Fund V, L.P. 10% Owner C-Conversion A Common Stock 582,408 0.00 582,408
2019-05-09 OSHEA WILLIAM J 10% Owner C-Conversion D Series A Preferred Stock 307,607 0.00 0
2019-05-09 New Enterprise Associates 16, L.P. 10% Owner C-Conversion A Common Stock 1,938,562 0.00 1,938,562
2019-05-09 Mellon Family Investment Co V 10% Owner P-Purchase A Common Stock 100,000 10.00 1.00M 347,156
2019-05-09 Meeker David P Director / 10% Owner C-Conversion D Series A Preferred Stock 95,712 0.00 0
2019-05-09 Makhzoumi Mohamad 10% Owner P-Purchase A Common Stock 1,500,000 10.00 15.00M 4,438,562

Executive team

Top executives
Shares Outstanding
141.93M

Executive compensation

Executive compensation (annual)
# Year Executive Salary Bonus Stock award Option award Incentive Other Total % Stock-
based
Filing
1 2025 Jennifer Good President and Chief Executive Officer 622.4K 343.8K 2.97M 10.5K 3.94M 75.24%
2 2025 James Cassella, Ph.D. Chief Development Officer 488.3K 196.0K 942.5K 10.5K 1.64M 57.56%
3 2025 Farrell Simon, Pharm. D. Chief Commercial Officer 370.1K 150.0K 825.3K 10.5K 1.36M 60.87%
4 2024 Jennifer Good President and Chief Executive Officer 607.9K 369.0K 1.60M 10.4K 2.59M 61.87%
5 2024 James Cassella, Ph.D. Chief Development Officer 120.0K 53.7K 1.16M 105.7K 1.44M 80.61%
6 2024 Lisa Delfini Chief Financial Officer 412.2K 182.2K 582.7K 10.4K 1.19M 49.08%
7 2023 Jennifer Good President and Chief Executive Officer 596.9K 229.1K 851.4K 9.9K 1.69M 50.46%
8 2023 Thomas Sciascia, M.D. Chief Scientific Officer 424.7K 117.6K 425.7K 9.1K 977.1K 43.57%
9 2023 David J. Clark, M.D., MBChB Chief Medical Officer 479.0K 131.6K 610.6K 0.00%
10 2022 Jennifer Good President and Chief Executive Officer 523.2K 249.5K 116.2K 9.2K 898.1K 12.94%
11 2022 David J. Clark, M.D., MBChB Chief Medical Officer 54.2K 526.6K 580.8K 90.66%
12 2022 Thomas Sciascia, M.D. Chief Scientific Officer 391.5K 130.8K 46.8K 8.2K 577.3K 8.11%
13 2021 Jennifer Good President and Chief Executive Officer 506.0K 216.8K 796.0K 8.7K 1.53M 52.12%
14 2021 William Forbes, Pharm. D. Chief Development Officer 406.7K 153.0K 621.1K 1.18M 52.60%
15 2021 Thomas Sciascia, M.D. Chief Scientific Officer 378.8K 113.1K 217.9K 7.8K 717.5K 30.37%
16 2021 Thomas Sciascia, M.D. Chief Medical Officer 378.8K 113.1K 217.9K 7.8K 717.5K 30.37%
17 2020 Jennifer Good President and Chief Executive Officer 477.7K 176.4K 778.8K 8.6K 1.44M 54.03%
18 2020 Yann Mazabraud Former Chief Commercial Officer and Head of International 302.4K 272.6K 141.9K 716.9K 38.03%
19 2020 Chris Seiter Former Chief Financial Officer 357.1K 99.3K 253.1K 6.7K 716.2K 35.34%
20 2020 Thomas Sciascia, M.D. Chief Medical Officer 368.6K 99.7K 233.6K 7.9K 709.9K 32.91%
21 2020 Thomas Sciascia Chief Medical Officer 368.6K 99.7K 233.6K 7.9K 709.9K 32.91%
22 2019 Jennifer Good President and Chief Executive Officer 434.6K 144.9K 2.22M 8.4K 2.81M 79.08%
23 2019 Yann Mazabraud Former Chief Commercial Officer and Head of International 325.7K 83.9K 358.5K 146.5K 914.7K 39.20%
24 2019 Yann Mazabraud Chief Commercial Officer and Head of International 325.7K 83.9K 358.5K 146.5K 914.7K 39.20%
25 2019 Thomas Sciascia Chief Medical Officer 339.3K 81.5K 358.5K 7.5K 786.8K 45.56%
26 2019 Thomas Sciascia, M.D. Chief Medical Officer 339.3K 81.5K 358.5K 7.5K 786.8K 45.56%
27 2018 Yann Mazabraud Chief Commercial Officer and Head of International 185.3K 35.2K 571.2K 221.2K 1.01M 56.39%
28 2018 Jennifer Good President and Chief Executive Officer 400.0K 120.0K 8.3K 528.3K 0.00%
CEO compensation breakdown

Proxy statements

Proxy statements (DEF 14A)
Filing date Form type Filing
2026-04-21 DEFA14A
2026-04-21 DEF 14A
2026-04-10 PRE 14A
2025-04-29 DEFA14A
2025-04-29 DEF 14A

Recent SEC filings

Recent SEC filings
Filing date Form type Filing
2026-05-05 8-K
2026-05-05 10-Q
2026-04-21 DEFA14A
2026-04-21 DEF 14A
2026-04-21 ARS
2026-04-17 8-K
2026-04-17 424B5
2026-04-16 424B5
2026-04-10 PRE 14A
2026-03-27 SC 13G/A

Executive team

NameTitleCompensationGender
Jennifer L. Good Co-Founder, Chief Executive Officer, President & Director 976.6K female
James V. Cassella Chief Development Officer 694.8K
Thomas R. Sciascia Co-Founder & Chief Scientific Officer 551.4K
Farrell Simon Chief Commercial Officer 530.6K male
David C. Hastings Chief Financial Officer & Principal Financial Officer male
Katherine Takaki Senior Vice President of Global Regulatory Affairs female
Katie McManus Communications Manager
Christopher Galletta Controller & Chief Accounting Officer male
ESG Rating
B
BIOTECHNOLOGY
2026
E (Environmental)
59.6 / 56.3
Company / Sector avg.
S (Social)
72.3 / 62.4
Company / Sector avg.
G (Governance)
70.7 / 60.9
Company / Sector avg.
ESG Total
67.5 / 59.9
Company / Sector avg.
ESG Score History BIOTECHNOLOGY
Benchmark vs Sector
Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend history

Earnings history

Earnings reports

Stock splits