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Stoke Therapeutics, Inc. (STOK)

USD29.24 -0.22 (-0.76%)
US NASDAQ Healthcare Biotechnology
Address 45 Wiggins Avenue 1730
Bedford, MA, US
CEO Ian F. Smith
IPO 2019-06-19
CIK 1623526 ISIN US86150R1077

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Description

Stoke Therapeutics, Inc. is an emerging biopharmaceutical company dedicated to developing innovative antisense oligonucleotide (ASO) therapies. Its primary focus is to target and address the fundamental causes of severe genetic disorders, particularly within the United States. The company employs its exclusive Targeted Augmentation of Nuclear Gene Output (TANGO) platform to engineer ASOs that precisely enhance protein expression. Stoke's most advanced candidate, STK-001, is currently progressing through Phase I/IIa clinical trials for Dravet syndrome, a severe and debilitating genetic epilepsy. Additionally, STK-002 is in the preclinical development stage for treating autosomal dominant optic atrophy. The company has also established a licensing and collaborative agreement with Acadia Pharmaceuticals Inc. to identify, develop, and market new RNA-based medicines for critical and rare genetic neurodevelopmental conditions impacting the central nervous system. Formerly known as ASOthera Pharmaceuticals, Inc., the company rebranded to Stoke Therapeutics, Inc. in May 2016. Founded in 2014, Stoke Therapeutics, Inc. maintains its headquarters in Bedford, Massachusetts.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
USD29.24 -0.22 (-0.76%)
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Volume Profile
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Liquidity & share structure
Average Volume
699.4K
Beta
1.18
Float Shares
48.93M
Free Float %
82.7%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
-0.76% -1.00% -4.92% +2.35% +29.88% +2.84% +237.89% +185.31% -8.85% +27.65% +27.65%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
vs.
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Analyst Consensus (15 ratings, all time) Buy
Price Targets & DCF
Current price
29.24
Low 35.00 +19.7%
Consensus 43.86 +50.0%
Median 40.00 +36.8%
High 60.00 +105.2%
Ratings Trend (MoM) 100% Bullish
Rating 2026-05 Change
Strong Buy 1 0
Buy 11 0
Hold 0 0
Sell 0 0
Strong Sell 0 0
Price Target Summary
Period # Analysts Avg Target
Last Month
Last Quarter 1
40.00
+36.8%
Last Year 10
39.80
+36.1%
All Time 17
35.12
+20.1%
Quality scores
Altman Z-Score
23.07
Safe zone
Piotroski F-Score
2 / 9
Weak
MOAT Score
2 / 10
No MOAT
Composite Rating
D+
Overall Score
1 / 5
Low
DCF Score
1 / 5
Low
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
1 / 5
Low
P/E Score
1 / 5
Low
P/Book Score
2 / 5
Medium
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
    +404.5% Q1'26: -96.1% (vs Q1'25)
  • EPS growth Biotechnology: +29.7%
    +92.7% Q1'26: -141.6% (vs Q1'25)
  • FCF margin FCF growth · Biotechnology: +16.2%
    -1.7% Q1'26: -978.2% (vs Q1'25)
  • EBIT margin Biotechnology: +0.0%
    -11.2% Q1'26: -857.6% (vs Q1'25)
  • ROIC Biotechnology: -16.1%
    -30.4% Q1'26: -390.2% (vs Q1'25)
  • Share dilution Biotechnology: -3.4%
    +9.7% Q1'26: +6.2% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    0.00× Q1'26: -0.02× (vs Q1'25)
Valuation Multiples From To
Price Forecast (3Y) From To
Model
Adjust
P/E
Theoretical Return — If Invested Today

* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.

DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (1.20) × ERP
WACC = 100% × Ke + 0% × Kd (4.0%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Current price: 29.24
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2022
actual
Dec 2023
actual
Dec 2024
actual
Dec 2025
actual
Dec 2026
9 Rev. Ana.
9 EPS Ana.
Dec 2027
7 Rev. Ana.
7 EPS Ana.
Dec 2028
9 Rev. Ana.
8 EPS Ana.
Dec 2029
4 Rev. Ana.
6 EPS Ana.
Dec 2030
4 Rev. Ana.
6 EPS Ana.
Revenue
12.41M
est: 11.70M (+6.0%)
8.78M
est: 15.16M (-42.1%)
36.56M
est: 17.92M (+104.0%)
184.42M
est: 188.80M (-2.3%)
26.32M
18.46M – 35.67M
-86.1% YoY
49.23M
35.85M – 59.15M
+87.0% YoY
122.48M
120.65M – 124.31M
+148.8% YoY
340.75M
163.80M – 548.82M
+178.2% YoY
561.65M
269.99M – 904.61M
+64.8% YoY
EBITDA
-102.81M
est: -2.34M (-4,294.5%)
-112.30M
est: -6.37M (-1,662.4%)
-99.20M
est: -7.53M (-1,216.5%)
-18.82M
est: -79.37M (+76.3%)
-11.07M
-15.00M – -7.76M
+86.1% YoY
-20.70M
-24.87M – -15.07M
-87.0% YoY
-51.49M
-52.26M – -50.72M
-148.8% YoY
-143.25M
-230.73M – -68.86M
-178.2% YoY
-236.12M
-380.31M – -113.50M
-64.8% YoY
EBIT
-104.36M
est: -2.34M (-4,360.6%)
-114.77M
est: -6.40M (-1,693.0%)
-101.37M
est: -7.57M (-1,239.3%)
-20.59M
est: -79.74M (+74.2%)
-11.12M
-15.07M – -7.80M
+86.1% YoY
-20.79M
-24.98M – -15.14M
-87.0% YoY
-51.73M
-52.50M – -50.96M
-148.8% YoY
-143.91M
-231.78M – -69.18M
-178.2% YoY
-237.20M
-382.05M – -114.02M
-64.8% YoY
Net Income
-101.07M
est: -144.83M (+30.2%)
-104.70M
est: -103.57M (-1.1%)
-88.98M
est: -120.98M (+26.4%)
-6.89M
est: 12.70M (-154.2%)
-214.92M
-218.62M – -174.56M
-1,792.9% YoY
-211.48M
-225.48M – -129.02M
+1.6% YoY
-147.64M
-202.28M – -40.46M
+30.2% YoY
1.11M
360.8K – 1.99M
+100.8% YoY
86.83M
28.21M – 155.76M
+7,720.0% YoY
SGA
38.92M
est: 26.15M (+48.8%)
41.32M
est: 31.96M (+29.3%)
48.79M
est: 37.79M (+29.1%)
67.09M
est: 398.10M (-83.1%)
55.50M
38.92M – 75.22M
-86.1% YoY
103.80M
75.58M – 124.71M
+87.0% YoY
258.26M
254.40M – 262.11M
+148.8% YoY
718.49M
345.37M – 1.16B
+178.2% YoY
1.18B
569.28M – 1.91B
+64.8% YoY
EPS
-2.60
est: -2.66 (+2.3%)
-2.38
est: -2.16 (-10.2%)
-1.65
est: -2.02 (+18.2%)
-0.12
est: 0.12 (-198.0%)
-3.25
-3.69 – -2.95
-2,755.4% YoY
-3.07
-3.81 – -2.18
+5.7% YoY
-2.14
-3.42 – -0.68
+30.3% YoY
0.02
0.01 – 0.03
+100.9% YoY
1.47
0.48 – 2.63
+7,720.0% YoY
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-07 D+ 1/5 1/5 1/5 1/5 1/5 1/5 2/5
2026-05-06 D+ 1/5 1/5 1/5 1/5 1/5 1/5 2/5
2026-05-05 D+ 1/5 1/5 1/5 1/5 1/5 1/5 2/5
2026-05-04 D+ 1/5 1/5 1/5 1/5 1/5 1/5 2/5
2026-05-01 D+ 1/5 1/5 1/5 1/5 1/5 1/5 2/5
2026-04-30 D+ 1/5 1/5 1/5 1/5 1/5 1/5 2/5
2026-04-29 D+ 1/5 1/5 1/5 1/5 1/5 1/5 2/5
2026-04-28 D+ 1/5 1/5 1/5 1/5 1/5 1/5 2/5
2026-04-27 D+ 1/5 1/5 1/5 1/5 1/5 1/5 2/5
2026-04-24 D+ 1/5 1/5 1/5 1/5 1/5 1/5 2/5
2026-04-23 D+ 1/5 1/5 1/5 1/5 1/5 1/5 2/5
2026-04-22 D+ 1/5 1/5 1/5 1/5 1/5 1/5 2/5
2026-04-21 D+ 1/5 1/5 1/5 1/5 1/5 1/5 2/5
2026-04-20 D+ 1/5 1/5 1/5 1/5 1/5 1/5 2/5
2026-04-17 D+ 1/5 1/5 1/5 1/5 1/5 1/5 2/5
2026-04-16 D+ 1/5 1/5 1/5 1/5 1/5 1/5 2/5
2026-04-15 D+ 1/5 1/5 1/5 1/5 1/5 1/5 2/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
-182.94M
OE per share TTM
-3.01
Owner's Yield
-8.85%
Maintenance CapEx ratio
Maint CapEx / Avg PPE
22.2%

Ownership Overview

Ownership breakdown
At a glance
Institutional holders
35
Total invested
57.53M
Insider transactions (90d)
1
Beneficial owners (>5%)
28
Beneficial owners (>5%)
# Reporting person Amount owned % of class Sole voting Shared voting Sole dispositive Shared dispositive Type Citizenship Filing date SEC filing
1 Montrago Trustees Limited 14.44M 39.30% 14.44M 10.00 OO Republic of Cyprus 2021-06-30
2 Skorpios Trust 14.44M 39.30% 14.44M 11.00 OO 2021-06-30
3 Ezbon International Limited 7.54M 20.50% 7.54M 10.00 CO British Virgin Islands 2021-06-30
4 Blue Horizon Enterprise Ltd. 6.91M 18.80% 6.91M 11.00 CO 2021-06-30
5 Baker Bros. Advisors (GP) LLC 4.37M 8.30% 4.37M 4.37M HC, OO Delaware 2024-11-14
6 Baker Bros. Advisors LP 4.37M 8.30% 4.37M 4.37M IA, PN Delaware 2024-11-14
7 Felix J. Baker 4.37M 8.30% 4.37M 4.37M HC, IN Delaware 2024-11-14
8 Julian C. Baker 4.37M 8.30% 4.37M 4.37M HC, IN Delaware 2024-11-14
9 Abigail P. Johnson 3.60M 9.94% 3.60M IN United States of America 2021-02-08
10 FMR LLC 3.60M 9.94% 696.6K 3.60M HC Delaware 2021-02-08
11 Jeremy C. Green 2.69M 7.40% 2.69M HC, IN Delaware 2021-02-16
12 Redmile Group, LLC 2.69M 7.40% 2.69M IA, OO Delaware 2021-02-16
13 Lynx1 Capital Management LP 2.66M 6.00% 2.66M PN Delaware 2023-11-06
14 Weston Nichols 2.66M 6.00% 2.66M IN Delaware 2023-11-06
15 Morgan Stanley 2.45M 6.20% 13.00 HC, CO Delaware. 2023-02-10
16 Morgan Stanley Capital Services LLC 2.43M 6.20% 13.00 BD, CO Delaware. 2023-02-10
17 27-0423711 2.28M 5.77% 2.28M 2.28M Delaware 2024-02-26
18 The Vanguard Group - 23-1945930 1.91M 5.20% 47.5K IA Pennsylvania For 2022-02-10
19 LLC 1.83M 5.58% 1.83M BD New York 2020-02-14
20 Gilder, Gagnon, Howe & Co. LLC 1.47M 4.06% BD New York 2021-02-16
21 Bihua Chen 1.44M 3.97% 1.44M IN United States 2021-02-16
22 Cormorant Asset Management, LP 1.44M 3.97% 1.44M PN Delaware 2021-02-16
23 Cormorant Private Healthcare Fund II, LP 538.8K 1.49% 538.8K PN Delaware 2021-02-16
24 Cormorant Private Healthcare GP II, LLC 538.8K 1.49% 538.8K OO Delaware 2021-02-16
25 Cormorant Private Healthcare Fund I, LP 449.0K 1.24% 449.0K PN Delaware 2021-02-16
26 Cormorant Private Healthcare GP, LLC 449.0K 1.24% 449.0K OO Delaware 2021-02-16
27 Cormorant Global Healthcare GP, LLC 434.5K 1.20% 434.5K OO Delaware 2021-02-16
28 Cormorant Global Healthcare Master Fund, LP 434.5K 1.20% 434.5K PN Cayman Islands 2021-02-16

Institutional Activity (13F)

Institutional ownership trend From To
13F snapshot — 2026 Q1
Investors holding
35
-156 vs prev Q
New positions
8
Closed positions
157
Increased
22
Reduced
4
Put/Call ratio
0.00
Calls held
Puts held
Top institutional holders
# Investor Shares / Δ Mkt value / Δ Own% / Δ Weight% / Δ Avg px / Perf. Hold / Status
1 16.6K +16.6K (+100.0%) 527.55M +527.6M (+100.0%) 0.03% +0.028 pp 0.46% +0.461 pp USD31.74 +0.0% 1 qtrs NEW
2 FMR LLC 5.60M -1.3M (-18.4%) 177.77M +16.4M (+10.2%) 9.56% -2.209 pp 0.01% +0.001 pp USD9.89 +220.9% 27 qtrs
3 RTW INVESTMENTS, LP 5.55M +423.3K (+8.3%) 176.06M +55.7M (+46.2%) 9.46% +0.684 pp 1.76% +0.280 pp USD12.78 +148.4% 27 qtrs
4 LYNX1 CAPITAL MANAGEMENT LP 5.40M +— (+0.0%) 171.54M +61.7M (+56.1%) 9.22% -0.041 pp 34.73% +12.360 pp USD8.50 +273.4% 10 qtrs
5 BLACKROCK, INC. 5.21M -774.9K (-12.9%) 165.45M +24.7M (+17.6%) 8.89% -1.367 pp 0.00% +0.000 pp USD12.33 +157.4% 6 qtrs
6 REDMILE GROUP, LLC 4.03M -141.5K (-3.4%) 128.04M +29.9M (+30.5%) 6.88% -0.273 pp 9.43% -0.118 pp USD11.49 +176.2% 27 qtrs
7 MORGAN STANLEY 3.55M +9.1K (+0.3%) 112.56M +29.4M (+35.4%) 6.05% -0.011 pp 0.01% +0.002 pp USD15.79 +101.0% 27 qtrs
8 BAKER BROS. ADVISORS LP 3.34M -1.3M (-28.0%) 105.91M -3.0M (-2.7%) 5.69% -2.248 pp 0.62% -0.167 pp USD11.11 +185.7% 14 qtrs
9 TORONTO DOMINION BANK 3.17M +— (+0.0%) 100.72M +26.1M (+35.1%) 5.41% -0.024 pp 0.15% +0.033 pp USD11.03 +187.8% 5 qtrs
10 VANGUARD GROUP INC 3.15M -14.6K (-0.5%) 99.96M +25.6M (+34.4%) 5.37% -0.049 pp 0.00% +0.000 pp USD19.21 +65.2% 27 qtrs
11 STATE STREET CORP 2.50M +1.1M (+75.2%) 79.29M +45.8M (+136.6%) 4.26% +1.819 pp 0.00% +0.002 pp USD23.79 +33.4% 26 qtrs
12 BVF INC/IL 2.27M +608.6K (+36.7%) 71.91M +33.0M (+84.7%) 3.87% +1.026 pp 2.42% +0.842 pp USD25.71 +23.5% 2 qtrs
13 SIREN, L.L.C. 2.25M +— (+0.0%) 71.33M +18.5M (+35.1%) 3.83% -0.017 pp 2.13% +0.062 pp USD10.55 +200.9% 5 qtrs
14 DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C) 1.82M +1.8M (+100.0%) 57.88M +57.9M (+100.0%) 3.11% +3.111 pp 0.74% +0.739 pp USD31.74 +0.0% 1 qtrs NEW
15 JANUS HENDERSON GROUP PLC 1.45M +1.1M (+333.8%) 46.03M +38.2M (+485.6%) 2.48% +1.902 pp 0.02% +0.017 pp USD29.72 +6.8% 7 qtrs
16 POLAR CAPITAL HOLDINGS PLC 1.27M -54.3K (-4.1%) 40.28M +9.2M (+29.5%) 2.17% -0.103 pp 0.16% +0.006 pp USD15.39 +106.2% 3 qtrs
17 ASSENAGON ASSET MANAGEMENT S.A. 1.23M +327.5K (+36.4%) 38.97M +17.8M (+84.2%) 2.09% +0.552 pp 0.05% +0.025 pp USD21.44 +48.0% 7 qtrs
18 POINT72 ASSET MANAGEMENT, L.P. 1.22M -84.5K (-6.5%) 38.79M +8.1M (+26.3%) 2.09% -0.154 pp 0.04% -0.008 pp USD23.50 +35.1% 2 qtrs
19 GEODE CAPITAL MANAGEMENT, LLC 1.17M +19.1K (+1.7%) 37.02M +10.1M (+37.3%) 1.99% +0.024 pp 0.00% +0.001 pp USD21.24 +49.4% 26 qtrs
20 GOLDMAN SACHS GROUP INC 1.14M -8.2K (-0.7%) 36.27M +9.2M (+34.1%) 1.95% -0.023 pp 0.00% +0.001 pp USD7.32 +333.6% 27 qtrs
21 DIMENSIONAL FUND ADVISORS LP 827.1K +148.8K (+21.9%) 26.25M +10.3M (+64.6%) 1.41% +0.249 pp 0.01% +0.002 pp USD16.03 +98.0% 22 qtrs
22 BIOIMPACT CAPITAL LLC 770.3K -19.4K (-2.5%) 24.45M +5.9M (+31.7%) 1.31% -0.039 pp 2.80% -0.240 pp USD11.79 +169.2% 6 qtrs
23 WELLINGTON MANAGEMENT GROUP LLP 735.8K -2.0K (-0.3%) 23.35M +6.0M (+34.7%) 1.26% -0.009 pp 0.00% +0.001 pp USD21.63 +46.7% 16 qtrs
24 OPALEYE MANAGEMENT INC. 695.0K +13.0K (+1.9%) 22.06M +6.0M (+37.6%) 1.19% +0.017 pp 2.91% +0.644 pp USD11.96 +165.4% 5 qtrs
25 CAPTION MANAGEMENT, LLC 502.1K +2.1K (+0.4%) 15.94M +4.2M (+35.6%) 0.86% 0.000 pp 0.11% +0.018 pp USD23.53 +34.9% 2 qtrs
26 TANG CAPITAL MANAGEMENT LLC 500.0K +— (+0.0%) 15.87M +4.1M (+35.1%) 0.85% -0.004 pp 0.78% +0.332 pp USD9.28 +242.0% 5 qtrs
27 CANDRIAM S.C.A. 446.7K +446.7K (+100.0%) 14.18M +14.2M (+100.0%) 0.76% +0.762 pp 0.07% +0.071 pp USD31.74 +0.0% 1 qtrs NEW
28 PARKMAN HEALTHCARE PARTNERS LLC 430.2K +180.2K (+72.1%) 13.65M +7.8M (+132.4%) 0.73% +0.306 pp 1.30% +0.687 pp USD26.95 +17.8% 2 qtrs
29 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 410.9K +8.0K (+2.0%) 13.04M +3.6M (+37.7%) 0.70% +0.011 pp 0.00% +0.001 pp USD20.25 +56.7% 26 qtrs
30 NORTHERN TRUST CORP 403.2K -11.7K (-2.8%) 12.80M +3.0M (+31.2%) 0.69% -0.023 pp 0.00% +0.000 pp USD16.73 +89.7% 26 qtrs
31 ERSTE ASSET MANAGEMENT GMBH 396.0K +— (+0.0%) 12.60M +2.8M (+28.6%) 0.68% -0.003 pp 0.11% +0.011 pp USD6.65 +377.3% 4 qtrs
32 PRICE T ROWE ASSOCIATES INC /MD/ 372.3K +321.1K (+626.3%) 11.82M +10.6M (+880.7%) 0.64% +0.547 pp 0.00% +0.001 pp USD31.53 +0.7% 27 qtrs
33 JPMORGAN CHASE & CO 277.9K +253.6K (+1,040.2%) 8.82M +8.2M (+1,440.0%) 0.47% +0.432 pp 0.00% +0.001 pp USD29.98 +5.9% 26 qtrs
34 BIRCHVIEW CAPITAL, LP 260.0K +50.0K (+23.8%) 8.25M +3.3M (+67.2%) 0.44% +0.084 pp 4.83% +1.106 pp USD12.03 +163.8% 24 qtrs
35 INVESCO LTD. 259.5K +51.5K (+24.7%) 8.24M +3.3M (+68.5%) 0.44% +0.086 pp 0.00% +0.001 pp USD22.98 +38.1% 7 qtrs
36 BAILLIE GIFFORD & CO 246.9K +246.9K (+100.0%) 7.84M +7.8M (+100.0%) 0.42% +0.421 pp 0.01% +0.007 pp USD31.74 +0.0% 1 qtrs NEW
37 RHENMAN & PARTNERS ASSET MANAGEMENT AB 216.0K -34.0K (-13.6%) 6.86M +980.8K (+16.7%) 0.37% -0.060 pp 0.64% -0.009 pp USD23.50 +35.1% 2 qtrs
38 BANK OF AMERICA CORP /DE/ 206.2K -43.3K (-17.4%) 6.54M +681.5K (+11.6%) 0.35% -0.076 pp 0.00% +0.000 pp USD6.87 +362.0% 26 qtrs
39 GRANAHAN INVESTMENT MANAGEMENT, LLC 191.4K -62.5K (-24.6%) 6.07M +108.3K (+1.8%) 0.33% -0.109 pp 0.26% +0.016 pp USD8.25 +284.7% 15 qtrs
40 UBS GROUP AG 169.7K -136.3K (-44.5%) 5.39M -1.8M (-25.1%) 0.29% -0.235 pp 0.00% 0.000 pp USD11.52 +175.5% 20 qtrs
41 FIRST TRUST ADVISORS LP 162.7K +10.4K (+6.8%) 5.16M +1.6M (+44.3%) 0.28% +0.017 pp 0.00% +0.001 pp USD24.03 +32.1% 2 qtrs
42 BARCLAYS PLC 150.9K +71.2K (+89.3%) 4.79M +3.8M (+388.9%) 0.26% +0.121 pp 0.00% +0.001 pp USD20.93 +51.6% 27 qtrs
43 BANK OF NEW YORK MELLON CORP 140.8K +20.4K (+16.9%) 4.47M +1.6M (+57.9%) 0.24% +0.034 pp 0.00% +0.000 pp USD20.38 +55.7% 26 qtrs
44 FRANKLIN RESOURCES INC 132.2K +16.4K (+14.1%) 4.20M +1.5M (+54.2%) 0.23% +0.027 pp 0.00% +0.000 pp USD17.41 +82.3% 8 qtrs
45 SUSQUEHANNA PORTFOLIO STRATEGIES, LLC 126.4K +— (+0.0%) 4.01M +1.0M (+35.1%) 0.22% -0.001 pp 0.06% +0.015 pp USD10.80 +193.9% 4 qtrs
46 GILDER GAGNON HOWE & CO LLC 122.4K -32.7K (-21.1%) 3.89M +240.1K (+6.6%) 0.21% -0.057 pp 0.04% +0.004 pp USD12.13 +161.7% 27 qtrs
47 EAM INVESTORS, LLC 117.8K -2.4K (-2.0%) 3.74M +961.1K (+34.6%) 0.20% -0.005 pp 0.42% +0.098 pp USD23.50 +35.1% 2 qtrs
48 HIGHVISTA STRATEGIES LLC 115.5K +115.5K (+100.0%) 3.67M +3.7M (+100.0%) 0.20% +0.197 pp 0.94% +0.944 pp USD31.74 +0.0% 1 qtrs NEW
49 AMERICAN CENTURY COMPANIES INC 115.1K +16.0K (+16.2%) 3.65M +1.3M (+56.9%) 0.20% +0.027 pp 0.00% +0.001 pp USD21.76 +45.9% 3 qtrs
50 DAFNA CAPITAL MANAGEMENT LLC 108.9K -60.9K (-35.9%) 3.46M -534.4K (-13.4%) 0.19% -0.105 pp 0.80% -0.183 pp USD9.56 +232.0% 8 qtrs
51 NUVEEN, LLC 104.3K -1.7K (-1.6%) 3.31M +818.4K (+32.9%) 0.18% -0.004 pp 0.00% +0.000 pp USD7.21 +340.2% 4 qtrs
52 RAFFERTY ASSET MANAGEMENT, LLC 90.2K +54.9K (+155.3%) 2.86M +2.0M (+244.8%) 0.15% +0.093 pp 0.01% +0.007 pp USD24.72 +28.4% 7 qtrs
53 PENSERRA CAPITAL MANAGEMENT LLC 88.5K -62.1K (-41.2%) 2.81M -730.0K (-20.6%) 0.15% -0.107 pp 0.03% -0.009 pp USD23.50 +35.1% 2 qtrs
54 QUANTEDGE CAPITAL PTE LTD 87.2K +47.2K (+118.0%) 2.77M +1.8M (+194.4%) 0.15% +0.080 pp 1.32% +0.805 pp USD27.96 +13.5% 2 qtrs
55 SWISS NATIONAL BANK 75.7K +1.6K (+2.2%) 2.40M +661.4K (+38.0%) 0.13% +0.002 pp 0.00% +0.000 pp USD15.39 +106.2% 7 qtrs
56 ALYESKA INVESTMENT GROUP, L.P. 75.0K +75.0K (+100.0%) 2.38M +2.4M (+100.0%) 0.13% +0.128 pp 0.01% +0.007 pp USD31.74 +0.0% 1 qtrs NEW
57 PALO ALTO INVESTORS LP 72.0K -33.4K (-31.7%) 2.29M -191.6K (-7.7%) 0.12% -0.058 pp 0.32% -0.140 pp USD13.49 +135.3% 8 qtrs
58 PRINCIPAL FINANCIAL GROUP INC 70.3K +25.1K (+55.5%) 2.23M +1.2M (+110.0%) 0.12% +0.042 pp 0.00% +0.001 pp USD26.44 +20.0% 2 qtrs
59 JANE STREET GROUP, LLC 67.1K +67.1K (+100.0%) 2.13M +2.1M (+100.0%) 0.11% +0.115 pp 0.00% +0.000 pp USD31.74 +0.0% 9 qtrs
60 ALPS ADVISORS INC 66.5K +21.8K (+48.9%) 2.11M +1.1M (+101.1%) 0.11% +0.037 pp 0.01% +0.006 pp USD20.69 +53.4% 5 qtrs
61 SCHONFELD STRATEGIC ADVISORS LLC 63.1K -174.9K (-73.5%) 2.00M -3.6M (-64.2%) 0.11% -0.300 pp 0.01% -0.023 pp USD13.93 +127.9% 5 qtrs
62 HUSSMAN STRATEGIC ADVISORS, INC. 63.0K +63.0K (+100.0%) 2.00M +2.0M (+100.0%) 0.11% +0.108 pp 0.48% +0.483 pp USD31.74 +0.0% 1 qtrs NEW
63 RHUMBLINE ADVISERS 62.4K -5.9K (-8.6%) 1.98M +375.9K (+23.4%) 0.11% -0.011 pp 0.00% +0.000 pp USD16.43 +93.2% 25 qtrs
64 UBS ASSET MANAGEMENT AMERICAS INC 57.2K -18.6K (-24.6%) 1.82M +33.2K (+1.9%) 0.10% -0.032 pp 0.00% +0.000 pp USD12.08 +162.7% 7 qtrs
65 PRIVIUM FUND MANAGEMENT B.V. 55.0K +55.0K (+100.0%) 1.75M +1.7M (+100.0%) 0.09% +0.094 pp 0.32% +0.321 pp USD31.74 +0.0% 1 qtrs NEW
66 WOODLINE PARTNERS LP 50.1K -45.0K (-47.3%) 1.59M -644.5K (-28.8%) 0.09% -0.078 pp 0.01% -0.004 pp USD10.74 +195.5% 12 qtrs
67 D. E. SHAW & CO., INC. 49.9K -2.7K (-5.2%) 1.58M +347.5K (+28.1%) 0.09% -0.005 pp 0.00% +0.000 pp USD16.41 +93.4% 14 qtrs
68 WELLS FARGO & COMPANY/MN 49.6K +21.5K (+76.6%) 1.57M +914.2K (+138.6%) 0.08% +0.037 pp 0.00% +0.000 pp USD21.06 +50.7% 26 qtrs
69 NOMURA HOLDINGS INC 44.4K -36.9K (-45.4%) 1.41M -500.7K (-26.2%) 0.08% -0.064 pp 0.00% -0.001 pp USD23.50 +35.1% 2 qtrs
70 CREATIVE PLANNING 41.7K -1.6K (-3.7%) 1.32M +306.3K (+30.1%) 0.07% -0.003 pp 0.00% +0.000 pp USD10.01 +217.1% 4 qtrs
71 VICTORY CAPITAL MANAGEMENT INC 41.1K +41.1K (+100.0%) 1.31M +1.3M (+100.0%) 0.07% +0.070 pp 0.00% +0.001 pp USD31.74 +0.0% 1 qtrs NEW
72 PLATINUM INVESTMENT MANAGEMENT LTD 40.8K +7.9K (+24.1%) 1.30M +522.3K (+67.6%) 0.07% +0.013 pp 0.30% +0.249 pp USD25.10 +26.5% 2 qtrs
73 ALLIANCEBERNSTEIN L.P. 40.6K +— (+0.0%) 1.29M +334.8K (+35.1%) 0.07% 0.000 pp 0.00% +0.000 pp USD17.11 +85.5% 24 qtrs
74 KENNONDALE CAPITAL MANAGEMENT LLC 38.7K -31.0K (-44.5%) 1.23M -409.4K (-25.0%) 0.07% -0.053 pp 0.90% -0.350 pp USD10.00 +217.4% 4 qtrs
75 HARVEST INVESTMENT SERVICES, LLC 38.3K +38.3K (+100.0%) 1.22M +1.2M (+100.0%) 0.07% +0.065 pp 0.23% +0.230 pp USD31.74 +0.0% 1 qtrs NEW
76 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 37.1K +5.1K (+15.8%) 1.18M +424.8K (+56.4%) 0.06% +0.008 pp 0.00% +0.000 pp USD16.46 +92.8% 26 qtrs
77 LEGAL & GENERAL GROUP PLC 36.4K -1.4K (-3.8%) 1.15M +266.4K (+30.0%) 0.06% -0.003 pp 0.00% +0.000 pp USD15.42 +105.8% 26 qtrs
78 CANADA PENSION PLAN INVESTMENT BOARD 35.2K +35.2K (+100.0%) 1.12M +1.1M (+100.0%) 0.06% +0.060 pp 0.00% +0.001 pp USD31.74 +0.0% 1 qtrs NEW
79 DEUTSCHE BANK AG\ 33.4K +9.2K (+37.9%) 1.06M +490.9K (+86.2%) 0.06% +0.016 pp 0.00% +0.000 pp USD18.81 +68.7% 26 qtrs
80 PROFUND ADVISORS LLC 33.4K +33.4K (+100.0%) 1.06M +1.1M (+100.0%) 0.06% +0.057 pp 0.03% +0.032 pp USD31.74 +0.0% 7 qtrs
81 MIRAE ASSET GLOBAL ETFS HOLDINGS LTD. 32.5K -17.9K (-35.6%) 1.03M -155.7K (-13.1%) 0.06% -0.031 pp 0.00% 0.000 pp USD12.17 +160.8% 7 qtrs
82 AQR CAPITAL MANAGEMENT LLC 29.5K +354.0 (+1.2%) 935.3K +251.1K (+36.7%) 0.05% +0.000 pp 0.00% +0.000 pp USD11.81 +168.8% 6 qtrs
83 READYSTATE ASSET MANAGEMENT LP 29.1K +29.1K (+100.0%) 922.3K +922.3K (+100.0%) 0.05% +0.050 pp 0.04% +0.037 pp USD31.74 +0.0% 1 qtrs NEW
84 J. GOLDMAN & CO LP 27.0K -6.8K (-20.1%) 857.0K +62.7K (+7.9%) 0.05% -0.012 pp 0.02% +0.003 pp USD23.50 +35.1% 2 qtrs
85 CRESSET ASSET MANAGEMENT, LLC 26.3K -411.0 (-1.5%) 835.6K +207.3K (+33.0%) 0.04% -0.001 pp 0.00% +0.001 pp USD23.50 +35.1% 2 qtrs
86 SUSQUEHANNA INTERNATIONAL GROUP, LLP 26.2K -14.3K (-35.3%) 831.6K -120.2K (-12.6%) 0.04% -0.025 pp 0.00% +0.000 pp USD7.40 +328.9% 8 qtrs
87 SG AMERICAS SECURITIES, LLC 25.8K +16.8K (+187.2%) 820.0K +609.0K (+288.6%) 0.04% +0.029 pp 0.00% +0.000 pp USD28.87 +9.9% 2 qtrs
88 METLIFE INVESTMENT MANAGEMENT, LLC 25.3K +— (+0.0%) 803.7K +208.6K (+35.1%) 0.04% 0.000 pp 0.00% +0.001 pp USD16.80 +88.9% 25 qtrs
89 ALLSPRING GLOBAL INVESTMENTS HOLDINGS, LLC 24.5K -10.6K (-30.2%) 755.9K -68.0K (-8.3%) 0.04% -0.018 pp 0.00% 0.000 pp USD11.35 +179.6% 3 qtrs
90 AMERIPRISE FINANCIAL INC 21.1K +80.0 (+0.4%) 669.0K +175.5K (+35.6%) 0.04% +0.000 pp 0.00% +0.000 pp USD23.53 +34.9% 2 qtrs
91 TUDOR INVESTMENT CORP ET AL 19.3K +19.3K (+100.0%) 612.9K +612.9K (+100.0%) 0.03% +0.033 pp 0.00% +0.001 pp USD31.74 +0.0% 1 qtrs NEW
92 MASSACHUSETTS FINANCIAL SERVICES CO /MA/ 19.1K +19.1K (+100.0%) 606.3K +606.3K (+100.0%) 0.03% +0.033 pp 0.00% +0.000 pp USD31.74 +0.0% 1 qtrs NEW
93 INTECH INVESTMENT MANAGEMENT LLC 18.7K +5.5K (+41.9%) 592.0K +283.1K (+91.6%) 0.03% +0.009 pp 0.01% +0.003 pp USD16.84 +88.5% 6 qtrs
94 DIADEMA PARTNERS LP 17.2K +17.2K (+100.0%) 545.3K +545.3K (+100.0%) 0.03% +0.029 pp 0.09% +0.094 pp USD31.74 +0.0% 1 qtrs NEW
95 SEI INVESTMENTS CO 16.6K +181.0 (+1.1%) 527.9K +141.3K (+36.6%) 0.03% +0.000 pp 0.00% +0.000 pp USD23.59 +34.5% 2 qtrs
96 AVIVA PLC 15.9K -6.4K (-28.9%) 503.7K -20.7K (-4.0%) 0.03% -0.011 pp 0.00% 0.000 pp USD11.35 +179.6% 3 qtrs
97 CITADEL ADVISORS LLC 15.9K -58.2K (-78.6%) 503.1K -1.2M (-71.1%) 0.03% -0.100 pp 0.00% 0.000 pp USD10.50 +202.3% 6 qtrs
Ownership breakdown by holder

Insider Activity

Insider Activity — Latest Quarter
Ratio by transactions
0.00
Bearish
Ratio by volume
0.00
Bearish
Buys
0
Sells
1
Shares acquired
Shares disposed
1.8K
Cash buys
Cash sales
1.00
Net activity
-1,838
Insider buys vs sells (history) From To
Recent insider transactions From To
Date Person Role Transaction A/D Security Shares Price Value Owned after D/I Filing
2026-05-01 Ticho Barry Officer S-Sale D Common Stock 2,243 32.79 73.5K 36,621 D
2026-04-03 Kahn Clare Director A-Award A Stock Option (Right to Buy) 30,782 32.79 1.01M 30,782 D
2026-04-01 Ticho Barry Officer S-Sale D Common Stock 1,838 32.66 60.0K 38,864 D
2026-03-20 Allan Jonathan Officer S-Sale D Common Stock 8,692 33.64 292.4K 20,144 D
2026-03-19 Ticho Barry Officer M-Exempt D Stock Option (Right to Buy) 1,365 2.19 3.0K 83,035 D
2026-03-18 Ticho Barry Officer S-Sale D Common Stock 6,100 31.28 190.8K 41,384 D
2026-03-18 Leggett Thomas Officer S-Sale D Common Stock 2,173 31.28 68.0K 10,381 D
2026-03-18 Hoitt Jason Officer S-Sale D Common Stock 30 32.85 985.50 10,276 D
2026-03-18 Allan Jonathan Officer S-Sale D Common Stock 72 32.85 2.4K 28,836 D
2026-03-17 Ticho Barry Officer S-Sale D Common Stock 3,577 32.74 117.1K 50,071 D
2026-03-17 Leggett Thomas Officer S-Sale D Common Stock 922 33.38 30.8K 12,554 D
2026-03-17 Hoitt Jason Officer S-Sale D Common Stock 748 33.38 25.0K 12,207 D
2026-03-17 Allan Jonathan Officer S-Sale D Common Stock 2,476 32.74 81.1K 35,255 D
2026-03-15 Ticho Barry Officer M-Exempt D Restricted Stock Units 13,100 0.00 13,100 D
2026-03-15 Leggett Thomas Officer M-Exempt A Common Stock 14,750 0.00 14,750 D
2026-03-15 Kaye Edward M. MD Director M-Exempt D Restricted Stock Units 35,500 0.00 35,500 D
2026-03-15 Hoitt Jason Officer M-Exempt D Restricted Stock Units 10,000 0.00 30,000 D
2026-03-15 Allan Jonathan Officer M-Exempt D Restricted Stock Units 7,475 0.00 7,475 D
2026-03-13 LEVIN ARTHUR A Director S-Sale D Common Stock 605 36.80 22.3K 4,237 D
2026-03-10 TZIANABOS ARTHUR Director / Officer M-Exempt D Stock Option (Right to Buy) 3,955 8.33 32.9K 118,696 D
2026-03-10 Krainer Adrian R. Director S-Sale D Common Stock 33,243 39.74 1.32M 283,302 D
2026-03-02 Krainer Adrian R. Director S-Sale D Common Stock 7,229 39.66 286.7K 316,545 D
2026-02-17 Ticho Barry Officer A-Award A Restricted Stock Units 40,000 0.00 40,000 D
2026-02-17 SMITH IAN F Director / Officer A-Award A Restricted Stock Units 129,000 0.00 129,000 D
2026-02-17 Leggett Thomas Officer A-Award A Restricted Stock Units 40,000 0.00 40,000 D
2026-02-17 Hoitt Jason Officer A-Award A Restricted Stock Units 48,000 0.00 48,000 D
2026-02-17 Allan Jonathan Officer A-Award A Restricted Stock Units 35,000 0.00 35,000 D
2025-12-31 LEVIN ARTHUR A Director M-Exempt A Common Stock 1,211 0.00 4,842 D
2025-12-08 Kaye Edward M. MD Director S-Sale D Common Stock 3,825 31.44 120.3K 58,729 D
2025-12-08 Allan Jonathan Officer S-Sale D Common Stock 1,300 31.60 41.1K 14,509 D
2025-12-05 Ticho Barry Officer S-Sale D Common Stock 1,673 31.33 52.4K 21,787 D
2025-12-05 Kaye Edward M. MD Director S-Sale D Common Stock 500 31.85 15.9K 62,554 D
2025-12-05 Allan Jonathan Officer S-Sale D Common Stock 1,004 31.33 31.5K 23,590 D
2025-12-04 Ticho Barry Officer S-Sale D Common Stock 323 31.32 10.1K 23,460 D
2025-12-04 Kaye Edward M. MD Director S-Sale D Common Stock 1,231 31.32 38.6K 71,102 D
2025-12-04 Allan Jonathan Officer S-Sale D Common Stock 824 30.76 25.3K 24,788 D
2025-12-03 Ticho Barry Officer S-Sale D Common Stock 1,225 30.85 37.8K 15,156 D
2025-12-03 Kaye Edward M. MD Director S-Sale D Common Stock 419 30.34 12.7K 51,956 D
2025-12-03 Allan Jonathan Officer M-Exempt D Performance Stock Units 6,000 0.00 0 D
2025-12-02 Ticho Barry Officer S-Sale D Common Stock 762 30.14 23.0K 17,170 D
2025-12-02 Kaye Edward M. MD Director S-Sale D Common Stock 661 29.56 19.5K 52,780 D
2025-12-02 Allan Jonathan Officer S-Sale D Common Stock 868 30.14 26.2K 21,904 D
2025-12-01 Ticho Barry Officer M-Exempt D Restricted Stock Units 11,981 0.00 0 D
2025-12-01 Kaye Edward M. MD Director M-Exempt D Restricted Stock Units 4,317 0.00 0 D
2025-12-01 Allan Jonathan Officer M-Exempt D Restricted Stock Units 12,357 0.00 0 D
2025-11-24 Krainer Adrian R. Director S-Sale D Common Stock 40,472 29.72 1.20M 323,774 D
2025-11-14 Krainer Adrian R. Director S-Sale D Common Stock 19,790 26.61 526.7K 384,928 D
2025-11-03 Ticho Barry Officer S-Sale D Common Stock 1,455 26.02 37.9K 7,895 D
2025-10-08 SMITH IAN F Director / Officer A-Award A Stock Option (Right to Buy) 570,000 30.50 17.39M 570,000 D
2025-10-08 Kaye Edward M. MD Director M-Exempt D Stock Option (Right to Buy) 25,000 0.60 15.0K 542,801 D
2025-10-03 Kaye Edward M. MD Director S-Sale D Common Stock 42,461 25.09 1.07M 49,124 D
2025-10-03 Allan Jonathan Officer M-Exempt D Stock Option (Right to Buy) 10,000 9.15 91.5K 34,800 D
2025-10-01 Ticho Barry Officer S-Sale D Common Stock 5,343 23.64 126.3K 13,126 D
2025-09-30 LEVIN ARTHUR A Director M-Exempt A Common Stock 1,211 0.00 3,631 D
2025-09-04 Kaye Edward M. MD Director D-Return D Employee Stock Option (Right to Buy) 178,500 8.33 1.49M 37,500 D
2025-09-03 Kaye Edward M. MD Director S-Sale D Common Stock 45,996 20.13 925.9K 91,585 D
2025-09-03 Allan Jonathan Officer S-Sale D Common Stock 6,345 20.07 127.3K 11,831 D
2025-09-02 Ticho Barry Officer S-Sale D Common Stock 5,501 19.87 109.3K 18,469 D
2025-09-02 Kaye Edward M. MD Director S-Sale D Common Stock 14,860 20.14 299.3K 137,581 D
2025-09-02 Allan Jonathan Officer M-Exempt A Common Stock 9,150 7.07 64.7K 33,098 D
2025-08-29 Kaye Edward M. MD Director S-Sale D Common Stock 1,029 20.00 20.6K 152,441 D
2025-08-29 Allan Jonathan Officer M-Exempt A Common Stock 850 7.07 6.0K 24,798 D
2025-08-18 Ticho Barry Officer S-Sale D Common Stock 2,805 18.24 51.2K 23,970 D
2025-08-18 Kaye Edward M. MD Director S-Sale D Common Stock 12,126 18.24 221.2K 153,470 D
2025-08-18 Allan Jonathan Officer S-Sale D Common Stock 1,683 18.24 30.7K 23,948 D
2025-08-14 Ticho Barry Officer M-Exempt D Performance Stock Units 10,000 0.00 10,000 D
2025-08-14 Kaye Edward M. MD Director A-Award A Performance Stock Units 52,500 0.00 52,500 D
2025-08-14 Allan Jonathan Officer M-Exempt A Common Stock 6,000 0.00 25,631 D
2025-08-13 Allan Jonathan Officer S-Sale D Common Stock 13,712 15.00 205.7K 19,631 D
2025-08-01 Ticho Barry Officer S-Sale D Common Stock 4,504 12.82 57.7K 16,775 D
2025-07-01 Ticho Barry Officer S-Sale D Common Stock 4,503 11.63 52.4K 21,279 D
2025-06-30 LEVIN ARTHUR A Director M-Exempt D Restricted Stock Units 1,210 0.00 2,422 D
2025-06-18 Hoitt Jason Officer Employee Stock Option (Right to Buy) 60,000 8.33 499.8K 0 D
2025-06-04 Skorpios Trust 10% Owner S-Sale D Common Stock 3,000,000 10.20 30.60M 3,906,181 I
2025-06-03 Ticho Barry Officer S-Sale D Common Stock 6,471 10.03 64.9K 25,782 D
2025-06-03 Smith Julie Director A-Award A Director Stock Option (Right to Buy) 29,747 10.90 324.2K 29,747 D
2025-06-03 Menzel Garry E Director A-Award A Director Stock Option (Right to Buy) 29,747 10.90 324.2K 29,747 D
2025-06-03 LEVIN ARTHUR A Director A-Award A Director Stock Option (Right to Buy) 29,747 10.90 324.2K 29,747 D
2025-06-03 Krainer Adrian R. Director A-Award A Director Stock Option (Right to Buy) 29,747 10.90 324.2K 29,747 D
2025-06-03 Harrison Seth Loring Director A-Award A Director Stock Option (Right to Buy) 29,747 10.90 324.2K 29,747 D
2025-06-03 Burstein Jennifer Director A-Award A Director Stock Option (Right to Buy) 29,747 10.90 324.2K 29,747 D
2025-06-02 Ticho Barry Officer S-Sale D Common Stock 1,745 10.00 17.5K 32,253 D
2025-05-02 Ticho Barry Officer S-Sale D Common Stock 22,790 10.03 228.5K 33,998 D
2025-05-01 Ticho Barry Officer S-Sale D Common Stock 3,841 10.00 38.4K 56,788 D
2025-03-31 LEVIN ARTHUR A Director M-Exempt A Common Stock 1,210 0.00 1,210 D
2025-03-20 Ticho Barry Officer A-Award A Employee Stock Option (Right to Buy) 64,000 8.33 533.1K 64,000 D
2025-03-20 TZIANABOS ARTHUR Director / Officer A-Award A Stock Option (Right to Buy) 122,651 8.33 1.02M 122,651 D
2025-03-20 SMITH IAN F Director / Officer A-Award A Stock Option (Right to Buy) 238,420 8.33 1.99M 238,420 D
2025-03-20 Leggett Thomas Officer A-Award A Employee Stock Option (Right to Buy) 89,000 8.33 741.4K 89,000 D
2025-03-20 Kaye Edward M. MD Director A-Award A Employee Stock Option (Right to Buy) 216,000 8.33 1.80M 216,000 D
2025-03-20 Allan Jonathan Officer A-Award A Employee Stock Option (Right to Buy) 72,000 8.33 599.8K 72,000 D
2025-03-19 Ticho Barry Officer S-Sale D Common Stock 3,333 8.27 27.6K 60,629 D
2025-03-19 LEVIN ARTHUR A Director A-Award A Restricted Stock Units 4,842 0.00 4,842 D
2025-03-19 Kaye Edward M. MD Director S-Sale D Common Stock 8,907 8.27 73.7K 139,346 D
2025-03-19 Allan Jonathan Officer S-Sale D Common Stock 1,945 8.27 16.1K 31,565 D
2025-03-18 Ticho Barry Officer S-Sale D Common Stock 3,884 8.67 33.7K 63,962 D
2025-03-18 Kaye Edward M. MD Director S-Sale D Common Stock 10,382 8.67 90.0K 148,253 D
2025-03-18 Allan Jonathan Officer S-Sale D Common Stock 2,266 8.67 19.6K 33,510 D
2025-03-15 Ticho Barry Officer M-Exempt D Restricted Stock Units 13,100 0.00 26,200 D
2025-03-15 Kaye Edward M. MD Director / Officer M-Exempt A Common Stock 26,250 0.00 158,635 D
2025-03-15 Allan Jonathan Officer M-Exempt A Common Stock 6,000 0.00 35,776 D
2024-12-30 Kaye Edward M. MD Director / Officer M-Exempt D Employee Stock Option (Right to Buy) 35,000 0.60 21.0K 567,801 D
2024-12-23 Skorpios Trust 10% Owner S-Sale D Common Stock 2,000,000 11.50 23.00M 6,906,181 I
2024-12-09 Ticho Barry Officer S-Sale D Common Stock 2,586 12.99 33.6K 44,746 D
2024-12-09 Kaye Edward M. MD Director / Officer S-Sale D Common Stock 6,786 12.99 88.2K 61,885 D
2024-12-09 Allan Jonathan Officer S-Sale D Common Stock 12,114 13.69 165.8K 23,028 D
2024-12-06 Ticho Barry Officer S-Sale D Common Stock 13,945 12.78 178.2K 47,332 D
2024-12-06 Kaye Edward M. MD Director / Officer S-Sale D Common Stock 6,170 12.78 78.8K 68,671 D
2024-12-06 Allan Jonathan Officer S-Sale D Common Stock 9,696 12.78 123.9K 35,142 D
2024-12-03 Ticho Barry Officer M-Exempt A Common Stock 10,000 0.00 61,277 D
2024-12-03 Kaye Edward M. MD Director / Officer M-Exempt A Common Stock 26,250 0.00 74,841 D
2024-12-03 Allan Jonathan Officer M-Exempt A Common Stock 6,000 0.00 44,838 D
2024-12-02 Ticho Barry Officer M-Exempt D Stock Option (Right to Buy) 10,000 0.60 6.0K 0 D
2024-12-01 Ticho Barry Officer M-Exempt A Common Stock 48,792 0.00 51,277 D
2024-12-01 Kaye Edward M. MD Director / Officer M-Exempt A Common Stock 21,591 0.00 48,591 D
2024-12-01 Allan Jonathan Officer M-Exempt D Restricted Stock Unit (RSU) 33,927 0.00 12,357 D
2024-11-01 Ticho Barry Officer M-Exempt A Common Stock 10,000 0.60 6.0K 12,485 D
2024-10-01 Ticho Barry Officer S-Sale D Common Stock 10,000 12.06 120.6K 2,485 D
2024-09-19 Skorpios Trust 10% Owner S-Sale D Common Stock 1,937,500 14.05 27.22M 8,906,181 I
2024-09-03 Ticho Barry Officer M-Exempt D Stock Option (Right to Buy) 10,000 0.60 6.0K 30,000
2024-08-01 Ticho Barry Officer M-Exempt D Stock Option (Right to Buy) 10,000 0.60 6.0K 40,000
2024-07-02 Nash Huw M. Officer S-Sale D Common Stock 2,467 13.10 32.3K 33
2024-07-01 Ticho Barry Officer S-Sale D Common Stock 10,000 13.75 137.5K 2,485
2024-06-05 TZIANABOS ARTHUR Director A-Award A Director Stock Option (Right to Buy) 7,639 16.41 125.4K 7,639
2024-06-05 Smith Julie Director A-Award A Director Stock Option (Right to Buy) 7,639 16.41 125.4K 7,639
2024-06-05 SMITH IAN F Director A-Award A Director Stock Option (Right to Buy) 7,639 16.41 125.4K 7,639
2024-06-05 Menzel Garry E Director A-Award A Director Stock Option (Right to Buy) 7,639 16.41 125.4K 7,639
2024-06-05 LEVIN ARTHUR A Director A-Award A Director Stock Option (Right to Buy) 7,639 16.41 125.4K 7,639
2024-06-05 Krainer Adrian R. Director A-Award A Director Stock Option (Right to Buy) 7,639 16.41 125.4K 7,639
2024-06-05 Harrison Seth Loring Director A-Award A Director Stock Option (Right to Buy) 7,639 16.41 125.4K 7,639
2024-06-05 Burstein Jennifer Director A-Award A Director Stock Option (Right to Buy) 7,639 16.41 125.4K 7,639
2024-06-03 Ticho Barry Officer M-Exempt D Stock Option (Right to Buy) 10,000 0.60 6.0K 60,000
2024-05-20 Nash Huw M. Officer S-Sale D Common Stock 50,000 15.39 769.5K 0
2024-05-20 Kaye Edward M. MD Director / Officer S-Sale D Common Stock 39,686 15.39 610.8K 29,664
2024-05-20 Allan Jonathan Officer M-Exempt D Stock Option (Right to Buy) 8,599 7.07 60.8K 25,801
2024-05-15 Leggett Thomas Officer A-Award A Stock Option (Right to Buy) 396,200 14.13 5.60M 396,200
2024-05-07 Leggett Thomas 0 0.00 0
2024-05-01 Ticho Barry Officer M-Exempt D Stock Option (Right to Buy) 10,000 0.60 6.0K 70,000
2024-04-17 Skorpios Trust 10% Owner S-Sale D Common Stock 3,600,000 11.60 41.76M 10,843,681
2024-04-01 Ticho Barry Officer M-Exempt D Stock Option (Right to Buy) 442 0.60 265.20 80,000
2024-04-01 Nash Huw M. Officer M-Exempt D Stock Option (Right to Buy) 50,000 0.40 20.0K 96,000
2024-03-28 Allan Jonathan Officer S-Sale D Common Stock 5,026 13.19 66.3K 2,698
2024-03-27 Tulipano Stephen J Officer A-Award A Employee Stock Option (Right to Buy) 60,000 14.17 850.2K 60,000
2024-03-27 Ticho Barry Officer A-Award A Restricted Stock Units 40,000 0.00 40,000
2024-03-27 Nash Huw M. Officer A-Award A Restricted Stock Units 40,000 0.00 40,000
2024-03-27 Kaye Edward M. MD Director / Officer A-Award A Restricted Stock Units 105,000 0.00 105,000
2024-03-27 Allan Jonathan Officer A-Award A Employee Stock Option (Right to Buy) 36,000 14.17 510.1K 36,000
2024-03-19 Tulipano Stephen J Officer S-Sale D Common Stock 4,116 6.10 25.1K 20,746
2024-03-19 Ticho Barry Officer S-Sale D Common Stock 4,116 6.10 25.1K 11,469
2024-03-19 Nash Huw M. Officer S-Sale D Common Stock 4,116 6.10 25.1K 11,329
2024-03-19 Kaye Edward M. MD Director / Officer S-Sale D Common Stock 11,150 6.10 68.0K 69,350
2024-03-19 Allan Jonathan Officer S-Sale D Common Stock 2,349 6.10 14.3K 7,724
2024-03-15 Tulipano Stephen J Officer M-Exempt A Common Stock 13,100 0.00 24,862
2024-03-15 Ticho Barry Officer M-Exempt D Restricted Stock Units 13,100 0.00 39,300
2024-03-15 Nash Huw M. Officer M-Exempt D Restricted Stock Units 13,100 0.00 39,300
2024-03-15 Kaye Edward M. MD Director / Officer M-Exempt D Restricted Stock Units 35,500 0.00 106,500
2024-03-15 Allan Jonathan Officer M-Exempt D Restricted Stock Units 7,475 0.00 22,425
2024-03-01 Ticho Barry Officer M-Exempt D Stock Option (Right to Buy) 5,504 0.60 3.3K 80,442
2024-02-13 TZIANABOS ARTHUR Director M-Exempt D Stock Option (Right to Buy) 31,739 2.19 69.5K 0
2024-02-01 Ticho Barry Officer S-Sale D Common Stock 10,000 4.80 48.0K 6,981
2024-01-02 Ticho Barry Officer S-Sale D Common Stock 10,000 5.74 57.4K 16,981
2023-12-01 Tulipano Stephen J Officer D-Return D Employee Stock Option (Right to Buy) 107,400 20.34 2.18M 0
2023-12-01 Ticho Barry Officer D-Return D Employee Stock Option (Right to Buy) 65,600 60.00 3.94M 0
2023-12-01 Nash Huw M. Officer A-Award A Restricted Stock Unit (RSU) 8,463 0.00 8,463
2023-12-01 Kaye Edward M. MD Director / Officer A-Award A Restricted Stock Unit (RSU) 25,908 0.00 25,908
2023-12-01 Allan Jonathan Officer A-Award A Restricted Stock Unit (RSU) 46,284 0.00 46,284
2023-09-19 SMITH IAN F Director 0 0.00 0
2023-07-03 Ticho Barry Officer S-Sale D Common Stock 15,000 10.60 159.0K 25,895
2023-06-21 Allan Jonathan Officer S-Sale D Common Stock 1,948 13.48 26.3K 0
2023-06-13 TZIANABOS ARTHUR Director A-Award A Director Stock Option (Right to Buy) 19,441 12.46 242.2K 19,441
2023-06-13 Smith Julie Director A-Award A Director Stock Option (Right to Buy) 19,441 12.46 242.2K 19,441
2023-06-13 Menzel Garry E Director A-Award A Director Stock Option (Right to Buy) 19,441 12.46 242.2K 19,441
2023-06-13 LEVIN ARTHUR A Director A-Award A Director Stock Option (Right to Buy) 19,441 12.46 242.2K 19,441
2023-06-13 Krainer Adrian R. Director A-Award A Director Stock Option (Right to Buy) 19,441 12.46 242.2K 19,441
2023-06-13 Harrison Seth Loring Director A-Award A Director Stock Option (Right to Buy) 19,441 12.46 242.2K 19,441
2023-06-13 Burstein Jennifer Director A-Award A Director Stock Option (Right to Buy) 19,441 12.46 242.2K 19,441
2023-06-01 Ticho Barry Officer S-Sale D Common Stock 15,000 11.13 167.0K 40,895
2023-05-04 Ticho Barry Officer S-Sale D Common Stock 653 10.00 6.5K 55,895
2023-05-03 Ticho Barry Officer S-Sale D Common Stock 24,697 10.14 250.4K 56,548
2023-05-02 Ticho Barry Officer S-Sale D Common Stock 5,513 10.00 55.1K 81,245
2023-05-01 Ticho Barry Officer S-Sale D Common Stock 24,967 10.00 249.8K 86,758
2023-03-27 Kaye Edward M. MD Director / Officer M-Exempt D Employee Stock Option (right to buy) 20,000 0.60 12.0K 602,801
2023-03-15 Tulipano Stephen J Officer A-Award A Restricted Stock Unit (RSU) 52,400 0.00 52,400
2023-03-15 Ticho Barry Officer A-Award A Restricted Stock Unite (RSU) 52,400 0.00 52,400
2023-03-15 Nash Huw M. Officer A-Award A Employee Stock Option (Right to Buy) 78,600 9.15 719.2K 78,600
2023-03-15 Kaye Edward M. MD Director / Officer A-Award A Restricted Stock Unit (RSU) 142,000 0.00 142,000
2023-03-15 Allan Jonathan Officer D Employee Stock Option (Right to Buy) 34,400 7.07 243.2K 0
2023-02-06 Ticho Barry Officer S-Sale D Common Stock 9,235 10.02 92.5K 111,725
2023-02-03 Ticho Barry Officer S-Sale D Common Stock 3,763 10.03 37.7K 120,960
2023-02-02 Ticho Barry Officer S-Sale D Common Stock 267 10.00 2.7K 124,723
2023-02-01 Ticho Barry Officer S-Sale D Common Stock 5,705 10.02 57.1K 124,990
2023-01-31 Ticho Barry Officer S-Sale D Common Stock 200 10.00 2.0K 130,695
2022-12-07 Tulipano Stephen J Officer A-Award A Employee Stock Option (Right to Buy) 62,000 0.00 62,000
2022-12-07 Ticho Barry Officer A-Award A Employee Stock Option (Right to Buy) 62,000 0.00 62,000
2022-12-07 Nash Huw M. Officer A-Award A Employee Stock Option (Right to Buy) 62,000 0.00 62,000
2022-12-07 Kaye Edward M. MD Officer A-Award A Employee Stock Option (Right to Buy) 167,050 0.00 167,050
2022-06-07 TZIANABOS ARTHUR Director A-Award A Director Stock Option (Right to Buy) 21,000 12.96 272.2K 21,000
2022-06-07 Smith Julie Director A-Award A Director Stock Option (Right to Buy) 21,000 0.00 21,000
2022-06-07 Menzel Garry E Director A-Award A Director Stock Option (Right to Buy) 21,000 0.00 21,000
2022-06-07 LEVIN ARTHUR A Director A-Award A Director Stock Option (Right to Buy) 21,000 0.00 21,000

Executive team

Top executives
EBIT / Employee
-160.9K
Shares Outstanding
59.15M

Executive compensation

Executive compensation (annual)
# Year Executive Salary Bonus Stock award Option award Incentive Other Total % Stock-
based
Filing
1 2025 Ian F. Smith Chief Executive Officer 170.6K 1.20M 11.59M 14.04M 38.8K 27.03M 94.80%
2 2025 Edward M. Kaye, M.D. Former Chief Executive Officer 148.7K 1.20M 1.30M 587.7K 3.23M 77.23%
3 2025 Jason Hoitt Chief Patient Officer 494.4K 333.2K 1.12M 306.0K 15.0K 2.27M 64.08%
4 2025 Thomas Leggett Chief Financial Officer 496.4K 491.5K 534.9K 297.8K 9.8K 1.83M 56.07%
5 2024 Edward M. Kaye, M.D. Former Chief Executive Officer 650.9K 2.98M 1.61M 358.0K 12.7K 5.61M 81.80%
6 2024 Thomas Leggett Chief Financial Officer 309.5K 4.02M 190.0K 4.52M 88.95%
CEO compensation breakdown

Proxy statements

Proxy statements (DEF 14A)
Filing date Form type Filing
2026-04-22 DEFA14A
2026-04-22 DEF 14A

Recent SEC filings

Recent SEC filings
Filing date Form type Filing
2026-05-07 8-K
2026-05-07 10-Q
2026-05-05 4
2026-04-22 DEFA14A
2026-04-22 DEF 14A
2026-04-22 ARS
2026-04-07 8-K
2026-04-07 4
2026-04-07 3
2026-04-03 4

Executive team

NameTitleCompensationGender
Ian F. Smith Chief Executive Officer & Director 1M male
Jason Hoitt Chief Patient Officer 815.4K male
Thomas Edward Leggett Chief Financial Officer 804.0K male
Edward Kaye Advisor & Director 736.4K
Barry S. Ticho FACC Chief Medical Officer 726.5K
Adrian R. Krainer Co-Founder & Independent Director 45.0K
Isabel Aznarez Co-Founder, Head of Research & Senior Vice President female
Doug Snow Director of Communications & Investor Relations
Jonathan Allan Corporate Secretary & General Counsel male
Sara Den Besten Chief People Officer female
Susan Willson Vice President of Corporate Communications
Dawn Kalmar Chief of Corporate Affairs & Strategic Partnerships female
ESG Rating
B
BIOTECHNOLOGY
2026
E (Environmental)
55.5 / 56.3
Company / Sector avg.
S (Social)
62.8 / 62.4
Company / Sector avg.
G (Governance)
58.0 / 60.9
Company / Sector avg.
ESG Total
58.7 / 59.9
Company / Sector avg.
ESG Score History BIOTECHNOLOGY
Benchmark vs Sector
Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend history

Earnings history

Earnings reports

Stock splits