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Senti Biosciences, Inc. (SNTI)

USD0.58 -0.38 (-39.71%)
US NASDAQ Healthcare Biotechnology
Address 2 Corporate Drive 94080
South San Francisco, CA, US
CEO Timothy K. Lu
IPO 2021-05-26
CIK 1854270 ISIN US8169441024

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Description

Senti Biosciences, Inc. is a pioneering company specializing in gene circuit technology. They focus on creating advanced cell and gene therapies that incorporate sophisticated gene circuits, essentially biological computers, to genetically reprogram cells. This allows the modified cells to interpret biological cues, make precise decisions, and react appropriately within their specific cellular surroundings. Their proprietary synthetic biology platform leverages readily available, "off-the-shelf" chimeric antigen receptor natural killer (CAR-NK) cells. This innovative approach is specifically designed to tackle formidable liquid and solid tumor cancers. Among their leading therapeutic candidates is SENTI-202. This "Logic Gated OR+NOT" off-the-shelf CAR-NK cell therapy is engineered to selectively identify and destroy acute myeloid leukemia (AML) cells, critically leaving healthy bone marrow unharmed. Another key program, SENTI-301, is a multi-armed, ready-to-use CAR-NK cell therapy being developed for the treatment of hepatocellular carcinoma (HCC). Additionally, SENTI-401, a Logic Gated (NOT) off-the-shelf CAR-NK cell therapy, aims to precisely eliminate colorectal cancer (CRC) cells without damaging the body's healthy tissues. Established in 2016, Senti Biosciences maintains its headquarters in South San Francisco, California.

Market Cap & Enterprise Value
Merger & Acquisition History
Target company Ticker Date Filing
Dynamics Special Purpose Corp. DYNS 2022-02-14 View
Technical Outlook
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Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
USD0.58 -0.38 (-39.71%)
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Volume Profile
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Liquidity & share structure
Average Volume
198.4K
Beta
2.05
Float Shares
8.09M
Free Float %
30.8%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
+8.00% +2.97% +12.03% +25.00% -35.40% +0.00% -67.60% -89.28% -98.96% -98.96% -98.96%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
vs.
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Analyst Consensus (4 ratings, all time) Buy
Price Targets & DCF
Current price
0.58
Low 6.00 +928.6%
Consensus 6.00 +928.6%
Median 6.00 +928.6%
High 6.00 +928.6%
Ratings Trend (MoM) 100% Bullish
Rating 2026-05 Change
Strong Buy 1 0
Buy 3 0
Hold 0 0
Sell 0 0
Strong Sell 0 0
Price Target Summary
Period # Analysts Avg Target
Last Month
Last Quarter
Last Year 1
6.00
+928.6%
All Time 1
6.00
+928.6%
Quality scores
Altman Z-Score
-17.39
Distress
Piotroski F-Score
2 / 9
Weak
MOAT Score
0 / 10
No MOAT
Composite Rating
D+
Overall Score
1 / 5
Low
DCF Score
1 / 5
Low
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
1 / 5
Low
P/E Score
1 / 5
Low
P/Book Score
2 / 5
Medium
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
  • EPS growth Biotechnology: +29.7%
    +76.2% Q1'26: +95.4% (vs Q1'25)
  • FCF margin FCF growth · Biotechnology: +16.2%
    -257,845.5%
  • EBIT margin Biotechnology: +0.0%
    -289,668.2%
  • ROIC Biotechnology: -16.1%
    -352.9% Q1'26: +0.0% (vs Q1'25)
  • Share dilution Biotechnology: -3.4%
    +4,792.0% Q1'26: +573.9% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    -0.48× Q1'26: -1.04× (vs Q1'25)
Valuation Multiples From To
DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (2.10) × ERP
WACC = 89% × Ke + 11% × Kd (4.1%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Current price: 0.58
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2022
actual
Dec 2023
actual
Dec 2024
actual
Dec 2025
actual
Dec 2026
3 Rev. Ana.
2 EPS Ana.
Dec 2027
3 Rev. Ana.
2 EPS Ana.
Dec 2028
3 Rev. Ana.
3 EPS Ana.
Dec 2029
2 Rev. Ana.
1 EPS Ana.
Dec 2030
1 Rev. Ana.
1 EPS Ana.
Revenue
3.29M
est: 5.37M (-38.8%)
1.98M
est: 3.46M (-42.8%)
est: 2.80M (-100.0%)
22.0K
est: 1.00M (-97.8%)
2.50M
2.50M – 2.50M
+150.0% YoY
12.7K
12.7K – 12.7K
-99.5% YoY
20.50M
20.50M – 20.50M
+161,635.7% YoY
56.75M
56.75M – 56.75M
+176.8% YoY
157.40M
157.40M – 157.40M
+177.4% YoY
EBITDA
-58.16M
est: -3.22M (-1,706.3%)
-61.34M
est: -2.08M (-2,853.7%)
-54.88M
est: -1.68M (-3,166.4%)
-60.09M
est: -600.0K (-9,915.0%)
-1.50M
-1.50M – -1.50M
-150.0% YoY
-7.6K
-7.6K – -7.6K
+99.5% YoY
-12.30M
-12.30M – -12.30M
-161,635.7% YoY
-34.05M
-34.05M – -34.05M
-176.8% YoY
-94.44M
-94.44M – -94.44M
-177.4% YoY
EBIT
-62.08M
est: -3.22M (-1,828.1%)
-66.77M
est: -2.08M (-3,115.1%)
-60.73M
est: -1.68M (-3,514.6%)
-63.73M
est: -600.0K (-10,521.2%)
-1.50M
-1.50M – -1.50M
-150.0% YoY
-7.6K
-7.6K – -7.6K
+99.5% YoY
-12.30M
-12.30M – -12.30M
-161,635.7% YoY
-34.05M
-34.05M – -34.05M
-176.8% YoY
-94.44M
-94.44M – -94.44M
-177.4% YoY
Net Income
-58.21M
est: -81.92M (+28.9%)
-71.06M
est: -77.59M (+8.4%)
-52.79M
est: -3.27B (+98.4%)
-61.44M
est: -564.84M (+89.1%)
-245.82M
-329.35M – -162.29M
+56.5% YoY
-201.23M
-201.23M – -201.23M
+18.1% YoY
-114.63M
-444.18M – -87.93M
+43.0% YoY
-225.96M
-225.96M – -225.96M
-97.1% YoY
32.60M
32.60M – 32.60M
+114.4% YoY
SGA
37.63M
est: 67.59M (-44.3%)
34.87M
est: 43.59M (-20.0%)
23.51M
est: 688.01M (-96.6%)
26.16M
est: 245.72M (-89.4%)
614.29M
614.29M – 614.29M
+150.0% YoY
3.11M
3.11M – 3.11M
-99.5% YoY
5.04B
5.04B – 5.04B
+161,635.7% YoY
13.94B
13.94B – 13.94B
+176.8% YoY
38.68B
38.68B – 38.68B
+177.4% YoY
EPS
-13.25
est: -17.83 (+25.7%)
-20.94
est: -17.50 (-19.7%)
-11.49
est: -14.54 (+21.0%)
-2.73
est: -2.65 (-3.2%)
-1.09
-1.46 – -0.72
+58.7% YoY
-0.90
-0.90 – -0.90
+18.1% YoY
-1.18
-1.98 – -0.39
-31.8% YoY
-1.01
-1.01 – -1.01
+14.8% YoY
0.15
0.15 – 0.15
+114.4% YoY
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-11 D+ 1/5 1/5 1/5 1/5 1/5 1/5 2/5
2026-05-08 D+ 1/5 1/5 1/5 1/5 1/5 1/5 2/5
2026-05-07 D+ 1/5 1/5 1/5 1/5 1/5 1/5 2/5
2026-05-06 D+ 1/5 1/5 1/5 1/5 1/5 1/5 2/5
2026-05-05 D+ 1/5 1/5 1/5 1/5 1/5 1/5 2/5
2026-05-04 D+ 1/5 1/5 1/5 1/5 1/5 1/5 2/5
2026-05-01 D+ 1/5 1/5 1/5 1/5 1/5 1/5 2/5
2026-04-30 D+ 1/5 1/5 1/5 1/5 1/5 1/5 2/5
2026-04-29 D+ 1/5 1/5 1/5 1/5 1/5 1/5 2/5
2026-04-28 D+ 1/5 1/5 1/5 1/5 1/5 1/5 2/5
2026-04-27 D+ 1/5 1/5 1/5 1/5 1/5 1/5 2/5
2026-04-24 D+ 1/5 1/5 1/5 1/5 1/5 1/5 2/5
2026-04-23 D+ 1/5 1/5 1/5 1/5 1/5 1/5 2/5
2026-04-22 D+ 1/5 1/5 1/5 1/5 1/5 1/5 2/5
2026-04-21 D+ 1/5 1/5 1/5 1/5 1/5 1/5 2/5
2026-04-20 D+ 1/5 1/5 1/5 1/5 1/5 1/5 2/5
2026-04-17 D+ 1/5 1/5 1/5 1/5 1/5 1/5 2/5
2026-04-16 D+ 1/5 1/5 1/5 1/5 1/5 1/5 2/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
-43.44M
OE per share TTM
-4.23
Owner's Yield
-189.44%
Maintenance CapEx ratio
Maint CapEx / Avg PPE
2,999.0%

Ownership Overview

Ownership breakdown
At a glance
Institutional holders
1
Total invested
357.8K
Insider transactions (90d)
0
Beneficial owners (>5%)
41
Beneficial owners (>5%)
# Reporting person Amount owned % of class Sole voting Shared voting Sole dispositive Shared dispositive Type Citizenship Filing date SEC filing
1 Bayer Aktiengesellschaft 5.88M 13.40% 5.88M HC, CO Citizenship or Place of Organization 2023-02-13
2 Bayer HealthCare LLC 5.88M 13.40% 5.88M CO Citizenship or Place of Organization 2023-02-13
3 Bayer US Holding LP 5.88M 13.40% 5.88M PN Citizenship or Place of Organization 2023-02-13
4 Bayer World Investments B.V. 5.88M 13.40% 5.88M CO Citizenship or Place of Organization 2023-02-13
5 15 GP, LLC 4.43M 10.10% 4.43M 4.43M OO Delaware Limited Liability Company 2022-07-15
6 Anthony A. Florence, Jr. 4.43M 10.10% 4.43M 4.43M IN States 2022-07-15
7 Baskett 4.43M 10.10% 4.43M 4.43M IN States 2022-07-15
8 Mohamad H. Makhzoumi 4.43M 10.10% 4.43M 4.43M IN States 2022-07-15
9 NEA Partners 15, L.P. 4.43M 10.10% 4.43M 4.43M PN Delaware Limited Partnership 2022-07-15
10 New Enterprise Associates 15, L.P. 4.43M 10.10% 4.43M 4.43M PN Delaware Limited Partnership 2022-07-15
11 Peter W. Sonsini 4.43M 10.10% 4.43M 4.43M IN States 2022-07-15
12 Scott D. Sandell 4.43M 10.10% 4.43M 4.43M IN States 2022-07-15
13 52-0556948 3.55M 8.10% 552.9K 3.23M IA Maryland 2023-02-14
14 Morgan Stanley Investment Management Inc. 2.89M 12.20% 2.89M 2.89M IA, CO Delaware. 2022-02-10
15 8VC GP I, LLC 2.54M 5.80% 2.54M 2.54M OO 2023-02-08
16 Joe Lonsdale 2.54M 5.80% 2.54M 2.54M IN 2023-02-08
17 8VC Fund I, L.P. 2.50M 5.70% 2.50M 2.50M PN 2023-02-08
18 ARK Investment Management LLC 2.38M 10.03% 2.38M 2.38M IA Delaware, United States 2021-09-10
19 Woodline Partners LP 2.00M 8.40% 2.00M 2.00M IA Delaware 2022-02-11
20 1,540,293 1.54M 6.49% 1.54M 1.54M CO Delaware 2022-02-11
21 Sculptor Capital Holding Corp. 1.54M 6.48% 1.54M CO Delaware 2021-12-29
22 Sculptor Capital Holding II LLC 1.54M 6.48% 1.54M CO Delaware 2021-12-29
23 Sculptor Capital II LP 1.54M 6.48% 1.54M IA Delaware 2021-12-29
24 Sculptor Capital LP 1.54M 6.48% 1.54M IA Delaware 2021-12-29
25 Sculptor Capital Management, Inc. 1.54M 6.48% 1.54M CO Delaware 2021-12-29
26 JPMORGAN CHASE & CO.13-2624428 1.33M 5.50% 1.33M 1.33M HC Delaware 2022-02-03
27 Sculptor SC II LP 684.1K 2.88% 684.1K CO Delaware 2021-12-29
28 (10) 547.8K 2.31% 547.8K 547.8K CO Delaware 2022-02-11
29 Sculptor Master Fund, Ltd. 546.8K 2.31% 546.8K CO Delaware 2021-12-29
30 Sculptor Special Funding, LP 546.8K 2.31% 546.8K CO Delaware 2021-12-29
31 Morgan Stanley 249.9K 0.60% 249.9K 249.9K HC, CO Delaware. 2023-02-09
32 Morgan Stanley Invesment Management Inc. 249.9K 0.60% 249.9K 249.9K IA, CO Delaware. 2023-02-09
33 163,471 163.5K 0.69% 163.5K 163.5K CO Delaware 2022-02-11
34 Sculptor Credit Opportunities Master Fund, Ltd. 163.2K 0.69% 163.2K CO Delaware 2021-12-29
35 MORGAN STANLEY INSTITUTIONAL FUND, INC. INCEPTION PORTFOLIO 144.6K 0.30% 144.6K 144.6K IV Delaware. 2023-02-09
36 0.61% 143.6K 0.61% 143.6K 143.6K CO Delaware 2022-02-11
37 Sculptor Enhanced Master Fund, Ltd. 143.3K 0.60% 143.3K CO Delaware 2021-12-29
38 8VC Entrepreneurs Fund I, L.P. 39.3K 0.10% 39.3K 39.3K PN 2023-02-08
39 Jeremy C. Green 0.00% HC, IN United Kingdom 2022-02-14
40 Redmile Capital Offshore Master Fund, Ltd. 0.00% FI, CO Cayman Islands 2022-02-14
41 Redmile Group, LLC 0.00% IA, OO Delaware 2022-02-14

Institutional Activity (13F)

Institutional ownership trend From To
13F snapshot — 2025 Q3
Investors holding
1
+0 vs prev Q
New positions
0
Closed positions
0
Increased
0
Reduced
0
Put/Call ratio
0.00
Calls held
Puts held
Top institutional holders
# Investor Shares / Δ Mkt value / Δ Own% / Δ Weight% / Δ Avg px / Perf. Hold / Status
1 8VC GP I, LLC -253.8K (-100.0%) -357.8K (-100.0%) 0.00% -0.973 pp 0.00% -0.460 pp USD 9 qtrs SOLD
Ownership breakdown by holder

ETF Ownership

Top ETFs holding this stock Held by 11 ETFs in our universe
# ETF Weight Est. AUM exposure TER
1 Vanguard Extended Market ETF VXF 0.00% 156.8K 0.05%
2 Vanguard U.S. Total Market Shares Index ETF VTS.AX 0.00% 743.85 0.03%
3 Vanguard U.S. Total Market Index ETF VUN.TO 0.00% 2.0K 0.17%
4 Vanguard U.S. Total Market Index ETF (CAD-hedged) VUS.TO 0.00% 150.86 0.17%
5 Vanguard Total Stock Market ETF VTI 0.00% 349.1K 0.03%
6 Vanguard All-Equity ETF Portfolio VEQT.TO 0.00% 765.47 0.22%
7 Vanguard Growth ETF Portfolio VGRO.TO 0.00% 416.27 0.22%
8 Vanguard Balanced ETF Portfolio VBAL.TO 0.00% 168.37 0.22%
9 Vanguard Conservative ETF Portfolio VCNS.TO 0.00% 18.55 0.22%
10 Vanguard Conservative Income ETF Portfolio VCIP.TO 0.00% 2.60 0.22%

Insider Activity

Insider Activity — Latest Quarter
Ratio by transactions
0.00
Bearish
Ratio by volume
0.00
Bearish
Buys
0
Sells
4
Shares acquired
Shares disposed
97.0K
Cash buys
Cash sales
Net activity
-96,998
Insider buys vs sells (history) From To
Recent insider transactions From To
Date Person Role Transaction A/D Security Shares Price Value Owned after D/I Filing
2026-03-09 Rajangam Kanya Officer F-InKind D Common Stock 10,757 0.00 74,843 D
2026-03-09 Lu Timothy K Director / Officer F-InKind D Common Stock 80,666 0.00 639,583 D
2026-02-02 Rajangam Kanya Officer F-InKind D Common Stock 1,384 0.00 85,600 D
2026-02-02 Lu Timothy K Director / Officer F-InKind D Common Stock 4,191 0.00 720,249 D
2025-07-18 Baum Bryan Daniel Director A-Award A Stock Option (Right to Buy) 43,900 1.95 85.6K 43,900 D
2025-06-25 Tang Donald F Director A-Award A Stock Option (Right to Buy) 21,950 2.05 45.0K 21,950 D
2025-06-25 Schulz Fran Director A-Award A Stock Option (Right to Buy) 21,950 2.05 45.0K 21,950 D
2025-06-25 Mathers Edward T Director A-Award A Stock Option (Right to Buy) 21,950 2.05 45.0K 21,950 D
2025-06-25 Hsiung Feng Director A-Award A Stock Option (Right to Buy) 21,950 2.05 45.0K 21,950 D
2025-06-25 Collins James J. Director A-Award A Stock Option (Right to Buy) 21,950 2.05 45.0K 21,950 D
2025-06-25 COOPERSTONE BRENDA Director A-Award A Stock Option (Right to Buy) 21,950 2.05 45.0K 21,950 D
2025-03-10 Rajangam Kanya Officer C-Conversion A Common Stock 33,000 2.25 74.3K 33,000 I
2025-03-10 New Enterprise Associates 15, L.P. 10% Owner C-Conversion A Common Stock 3,333,000 0.00 3,775,615 D
2025-03-10 Celadon Partners SPV 24 10% Owner C-Conversion A Common Stock 9,777,000 0.00 9,777,000 D
2025-03-10 BAYER HEALTHCARE LLC 10% Owner C-Conversion D Series A Convertible Preferred Stock 2,222 0.00 0 D
2025-03-07 Tang Donald F Director A-Award A Stock Option (Right to Buy) 43,900 3.52 154.5K 43,900 D
2025-03-07 Schulz Fran Director A-Award A Stock Option (Right to Buy) 43,900 3.52 154.5K 43,900 D
2025-03-07 Rajangam Kanya Officer A-Award A Common Stock 78,363 0.00 86,984 D
2025-03-07 Mathers Edward T Director A-Award A Stock Option (Right to Buy) 43,900 3.52 154.5K 43,900 D
2025-03-07 Lu Timothy K Director / Officer A-Award A Common Stock 642,358 0.00 724,440 D
2025-03-07 Hsiung Feng Director 0 0.00 0
2025-03-07 Cross John Harry III Officer A-Award A Stock Option (Right to Buy) 174,200 3.52 613.2K 174,200 D
2025-03-07 Collins James J. Director A-Award A Stock Option (Right to Buy) 43,900 3.52 154.5K 43,900 D
2025-03-07 COOPERSTONE BRENDA Director A-Award A Stock Option (Right to Buy) 43,900 3.52 154.5K 43,900 D
2025-03-06 Rajangam Kanya Officer A-Award A Stock Option (Right to Buy) 235,088 3.97 933.3K 235,088 D
2025-03-06 New Enterprise Associates 15, L.P. 10% Owner Earnout Rights (Common Stock) 13,711 0.00 0 D
2025-03-06 Lu Timothy K Director / Officer A-Award A Stock Option (Right to Buy) 1,927,073 3.97 7.65M 1,927,073 D
2025-03-06 Celadon Partners SPV 24 10% Owner Series A Convertible Preferred Stock 9,777,000 2.25 22.00M 0 D
2025-03-03 Cross John Harry III Officer 0 0.00 0
2025-02-06 Rajangam Kanya Officer S-Sale D Common Stock 182 4.37 795.34 8,621 D
2025-02-06 Lu Timothy K Director / Officer S-Sale D Common Stock 545 4.36 2.4K 82,082 D
2025-02-04 Rajangam Kanya Officer S-Sale D Common Stock 1,297 4.07 5.3K 8,803 D
2025-02-04 Lu Timothy K Director / Officer S-Sale D Common Stock 3,922 4.07 16.0K 82,627 D
2024-12-09 Tang Donald F Director Common Stock 0 0.00 10,368 D
2024-12-09 Schulz Fran Director 0 0.00 0
2024-12-09 Rajangam Kanya Officer A-Award A Series A Convertible Preferred Stock 33 2.25 74.25 33 I
2024-12-09 BAYER HEALTHCARE LLC 10% Owner P-Purchase A Series A Convertible Preferred Stock 2,222 0.00 2,222 D
2024-07-10 Mathers Edward T Director A-Award A Stock Option (Right to Buy) 62,500 0.31 19.4K 62,500
2024-07-10 Farokhzad Omid Director A-Award A Stock Option (Right to Buy) 62,500 0.31 19.4K 62,500
2024-07-10 Collins James J. Director A-Award A Stock Option (Right to Buy) 62,500 0.31 19.4K 62,500
2024-07-10 COOPERSTONE BRENDA Director A-Award A Stock Option (Right to Buy) 62,500 0.31 19.4K 62,500
2024-05-04 Li Yvonne Officer 0 0.00 0
2024-02-01 Rajangam Kanya Officer A-Award A Stock Option (Right to Buy) 152,000 0.46 69.9K 152,000
2024-02-01 Lu Timothy K Director / Officer A-Award A Stock Option (Right to Buy) 459,000 0.46 211.1K 459,000
2024-02-01 KNOBELMAN DEBORAH Officer A-Award A Common Stock 101,000 0.00 131,000
2023-06-16 Mathers Edward T Director A-Award A Stock Option (Right to Buy) 62,500 0.99 61.9K 62,500
2023-06-16 Farokhzad Omid Director A-Award A Stock Option (Right to Buy) 62,500 0.99 61.9K 62,500
2023-06-16 Collins James J. Director A-Award A Stock Option (Right to Buy) 62,500 0.99 61.9K 62,500
2023-06-16 COOPERSTONE BRENDA Director A-Award A Stock Option (Right to Buy) 62,500 0.99 61.9K 62,500
2023-06-16 Berland Susan D Director A-Award A Stock Option (Right to Buy) 62,500 0.99 61.9K 62,500
2023-02-01 Rajangam Kanya Officer A-Award A Stock Option (Right to Buy) 130,000 1.81 235.3K 130,000
2023-02-01 Lu Timothy K Director / Officer A-Award A Stock Option (Right to Buy) 630,000 1.81 1.14M 630,000
2023-02-01 Lee Philip J Officer A-Award A Stock Option (Right to Buy) 195,000 1.81 353.0K 195,000
2023-02-01 KNOBELMAN DEBORAH Officer A-Award A Stock Option (Right to Buy) 130,000 1.81 235.3K 130,000
2022-10-03 KNOBELMAN DEBORAH Officer A-Award A Stock Option (Right to Buy) 240,000 0.00 240,000
2022-07-18 Rajangam Kanya Officer A-Award A Stock Option (Right to Buy) 327,750 1.80 590.0K 327,750
2022-07-13 Mathers Edward T Director A-Award A Stock Option (Right to Buy) 125,000 0.00 125,000
2022-07-13 Farokhzad Omid Director A-Award A Stock Option (Right to Buy) 125,000 0.00 125,000
2022-07-13 Epstein David R Director A-Award A Stock Option (Right to Buy) 125,000 0.00 125,000
2022-07-13 Collins James J. Director A-Award A Stock Option (Right to Buy) 125,000 1.75 218.8K 125,000
2022-07-13 COOPERSTONE BRENDA Director A-Award A Stock Option (Right to Buy) 125,000 0.00 125,000
2022-07-13 Berland Susan D Director A-Award A Stock Option (Right to Buy) 125,000 0.00 125,000
2022-07-05 Rajangam Kanya Officer 0 0.00 0
2022-06-08 New Enterprise Associates 15, L.P. 10% Owner D Common Stock 0 0.00 4,426,151
2022-06-08 Mathers Edward T Director 0 0.00 0
2022-06-08 Lu Timothy K Director / Officer I Common Stock 0 0.00 528,390
2022-06-08 Lee Philip J Officer D Common Stock 0 0.00 936,424
2022-06-08 KNOBELMAN DEBORAH Officer D Stock Option (Right to Buy) 146,775 7.87 1.16M 0
2022-06-08 Herberts Curt A. III Officer I Earnout Rights (Common Stock) 19,603 0.00 0
2022-06-08 Farokhzad Omid Director 0 0.00 0
2022-06-08 Epstein David R Director A-Award A Common Stock 112,519 0.00 123,252
2022-06-08 Dynamics Sponsor LLC Director J-Other D Common Stock 6,465,500 0.00 0
2022-06-08 Collins James J. Director D Common Stock 0 0.00 176,130
2022-06-08 COOPERSTONE BRENDA Director D Stock Option (Right to Buy) 31,438 3.12 98.1K 0
2022-06-08 Berland Susan D Director D Stock Option (Right to Buy) 17,613 7.87 138.6K 0
2022-06-08 BAYER HEALTHCARE LLC 10% Owner D Common Stock 0 0.00 5,878,488
2021-05-25 Ronaghi Mostafa Director / Officer I Class B common stock 5,750,000 0.00 0
2021-05-25 Nishar Dipchand Director I Class B common stock 112,519 0.00 0
2021-05-25 Farokhzad Omid Director I Class A common stock 0 0.00 715,500
2021-05-25 FLATLEY JAY T Director I Class B common stock 112,519 0.00 0
2021-05-25 Epstein David R Director I Class A common stock 0 0.00 10,733
2021-05-25 Dynamics Sponsor LLC 10% Owner D Class B common stock 5,750,000 0.00 0
2021-05-25 Chapman Rowan E Officer 0 0.00 0
2021-05-25 Afrasiabi Mark Officer 0 0.00 0
2014-06-25 MARTELL RON Director / Officer A-Award A Employee Stock Option 400,000 2.66 1.06M 400,000
2014-06-13 FROST PHILLIP MD ET AL Director / 10% Owner A-Award A Series A Warrants 333,333 3.00 1,000.0K 333,333
2014-05-16 Rubin Steven D Director 0 0.00 0
2014-05-16 RIOS MIGUEL DE LOS Officer 0 0.00 0
2014-05-16 FROST PHILLIP MD ET AL Director / 10% Owner A-Award A Warrant 646 2.00 1.3K 646
2014-05-14 Waksal Harlan Director A-Award A Common Stock Option 21,932 2.77 60.8K 54,298
2014-05-14 RECTOR DAVID Director A-Award A Common Stock Option 21,074 2.77 58.4K 41,682
2014-05-14 FORBES CHRISTOPHER Director A-Award A Common Stock Option 17,464 2.77 48.4K 36,406
2014-05-14 BRACA JOHN N Director A-Award A Common Stock Option 21,074 2.77 58.4K 40,946
2013-12-19 Browne Leslie J Director / Officer P-Purchase A Common Stock 800 4.15 3.3K 1,290
2013-12-16 FROST PHILLIP MD ET AL Director / 10% Owner I Warrants 333,333 4.00 1.33M 0
2013-09-13 Waksal Harlan Director A-Award A Common Stock Option 530,000 0.05 28.6K 3,236,572
2013-09-13 THOMPSON JOHN PHD Director / Officer A-Award A Common Stock Option 985,000 0.05 53.2K 2,203,276
2013-09-13 RECTOR DAVID Director A-Award A Common Stock Option 371,000 0.05 20.0K 2,080,765
2013-09-13 FORBES CHRISTOPHER Director A-Award A Common Stock Option 318,000 0.05 17.2K 2,002,193
2013-09-13 Dondero Richard S Officer A-Award A Common Stock Option 985,000 0.05 53.2K 2,360,124
2013-09-13 Browne Leslie J Director / Officer A-Award A Common Stock Option 1,723,000 0.05 93.0K 4,157,800
2013-09-13 BRACA JOHN N Director A-Award A Common Stock Option 371,000 0.05 20.0K 1,992,215
2013-05-20 Browne Leslie J Director / Officer P-Purchase A Common Stock 30,000 0.04 1.2K 49,000
2013-05-17 Waksal Harlan Director A-Award A Common Stock Option 273,256 0.04 11.8K 2,716,572
2013-05-17 RECTOR DAVID Director A-Award A Common Stock Option 244,186 0.04 10.5K 1,704,765
2013-05-17 FORBES CHRISTOPHER Director A-Award A Common Stock Option 238,372 0.04 10.2K 1,684,193
2013-05-17 BRACA JOHN N Director A-Award A Common Stock Option 139,534 0.04 6.0K 1,621,215
2013-02-19 Waksal Harlan Director A-Award A Common Stock Option 145,834 0.13 19.3K 2,433,316
2013-02-19 RECTOR DAVID Director A-Award A Common Stock Options 96,590 0.13 12.7K 1,460,579
2013-02-19 FORBES CHRISTOPHER Director / 10% Owner A-Award A Common Stock Option 89,016 0.15 13.4K 1,495,821
2013-02-19 BRACA JOHN N Director A-Award A Common Stock Option 56,818 0.13 7.5K 1,481,681

Executive team

Top executives
EBIT / Employee
-18.7K
Shares Outstanding
26.29M

Executive compensation

Executive compensation (annual)
# Year Executive Salary Bonus Stock award Option award Incentive Other Total % Stock-
based
Filing
1 2024 Timothy Lu, M.D., Ph.D. Chief Executive Officer 618.8K 140.8K 159.1K 442.4K 12.0K 930.7K 32.22%
2 2024 Kanya Rajangam, M.D., Ph.D. President, Head of Research and Development and Chief Medical Officer 526.8K 46.5K 52.7K 265.5K 1.8K 858.8K 11.55%
3 2024 Yvonne Li, Interim Chief Financial Officer 547.5K 547.5K 0.00%
4 2024 Yvonne Li Former Chief Financial Officer 547.5K 547.5K 0.00%
5 2023 Timothy Lu, M.D., Ph.D. Chief Executive Officer 606.6K 817.9K 250.2K 11.7K 1.69M 48.50%
6 2023 Deborah Knobelman, Ph.D. Former Chief Financial Officer, Treasurer and Head of Corporate Development 460.0K 168.8K 154.6K 6.3K 789.7K 21.37%
7 2023 Kanya Rajangam, M.D., Ph.D. President, Head of Research and Development and Chief Medical Officer 516.5K 168.8K 173.5K 627.7K 26.89%
8 2022 Deborah Knobelman, Ph.D. Former Chief Financial Officer, Treasurer and Head of Corporate Development 425.0K 75.0K 428.2K 170.0K 5.2K 1.10M 45.60%
9 2022 Deborah Knobelman, Ph.D. Chief Financial Officer, Treasurer and Head of Corporate Development 425.0K 75.0K 428.2K 170.0K 5.2K 1.10M 45.60%
10 2022 Kanya Rajangam, M.D., Ph.D. President, Head of Research and Development and Chief Medical Officer 241.3K 90.0K 412.7K 96.5K 840.5K 49.10%
11 2022 Kanya Rajangam, M.D., Ph.D. Head of Research and Development and Chief Medical Officer 241.3K 90.0K 412.7K 96.5K 840.5K 49.10%
12 2022 Timothy Lu, M.D., Ph.D. Chief Executive Officer 537.6K 268.8K 4.8K 811.3K 0.00%
13 2022 Timothy Lu, M.D.,Ph.D. President and Chief Executive Officer 537.6K 268.8K 4.8K 811.3K 0.00%
14 2021 Timothy Lu, M.D.,Ph.D. President and Chief Executive Officer 475.0K 23.80M 219.2K 24.50M 97.17%
CEO compensation breakdown

Proxy statements

Proxy statements (DEF 14A)
Filing date Form type Filing
2025-04-30 DEFA14A
2025-04-30 DEF 14A
2025-01-27 DEF 14A
2025-01-15 PRE 14A

Recent SEC filings

Recent SEC filings
Filing date Form type Filing
2026-05-04 SC 13D/A
2026-05-01 8-K
2026-05-01 424B5
2026-04-29 EFFECT
2026-04-29 EFFECT
2026-04-29 EFFECT
2026-04-29 EFFECT
2026-04-29 10-K/A
2026-04-24 S-8 POS
2026-04-24 S-8 POS

Executive team

NameTitleCompensationGender
Kanya Rajangam President, Head of Research & Development and Chief Medical Officer 794.0K
Timothy K. Lu Co-Founder, Chief Executive Officer & Director 630.8K
James J. Collins Scientific Co-Founder, Chairperson of Scientific Advisory Board & Independent Director 43.9K
Robert H. Cutler Senior Vice President & Head of Legal Affairs male
Thomas Chung Vice President of Strategic Finance & Corporate Development male
Dee Olomajeye Dragon Senior VP of People & Culture Strategy & Head of Administrative Operations female
Wilson Wong Scientific Co-Founder & Member of Scientific Advisory Board
Faraz Siddiqui Senior Vice President of Technical Operations male
Jay Cross Chief Financial Officer male
ESG Rating
B+
BIOTECHNOLOGY
2025
E (Environmental)
54.2 / 56.3
Company / Sector avg.
S (Social)
61.8 / 62.4
Company / Sector avg.
G (Governance)
58.1 / 60.9
Company / Sector avg.
ESG Total
58.0 / 59.9
Company / Sector avg.
ESG Score History BIOTECHNOLOGY
Benchmark vs Sector
Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend history

Earnings history

Earnings reports

Stock splits