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Syndax Pharmaceuticals, Inc. (SNDX)

USD22.89 -0.72 (-3.05%)
US NASDAQ Healthcare Biotechnology
Address 35 Gatehouse Drive 2451
New York City, MA, US
CEO Michael A. Metzger
Website syndax.com
IPO 2016-03-02
CIK 1395937 ISIN US87164F1057

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Description

Syndax Pharmaceuticals, Inc. operates as a clinical-stage biopharmaceutical firm focused on developing innovative therapies for cancer. Among its leading investigational products are SNDX-5613, currently undergoing Phase 1/2 clinical assessment, which targets the Menin-mixed lineage leukemia 1 protein interaction for treating MLL-rearranged (MLLr) and nucleophosmin 1 mutant acute myeloid leukemia (NPM1c AML). Another significant candidate is SNDX-6352, or axatilimab, a monoclonal antibody designed to block the colony stimulating factor 1 (CSF-1) receptor, intended for patients suffering from chronic graft versus host disease (cGVHD). The company is additionally progressing Entinostat. Syndax has also established strategic collaborations, including a research and development agreement with the National Cancer Institute, a clinical trial agreement with the Eastern Cooperative Oncology Group, and a license agreement with Kyowa Hakko Kirin Co., Ltd. Founded in 2005, Syndax Pharmaceuticals, Inc. maintains its corporate headquarters in Waltham, Massachusetts.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
USD22.89 -0.72 (-3.05%)
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Volume Profile
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Liquidity & share structure
Average Volume
2M
Beta
0.37
Float Shares
75.04M
Free Float %
85.1%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
-4.54% -0.63% -15.84% -0.34% +22.51% -2.86% +100.29% -3.50% +12.70% +60.08% +70.08%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
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Annual Monthly Returns
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Daily Returns Distribution
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Analyst Consensus (22 ratings, all time) Buy
Price Targets & DCF
Current price
22.89
Low 37.00 +61.6%
Consensus 41.50 +81.3%
Median 41.50 +81.3%
High 46.00 +101.0%
DCF (Unlevered) 15.08 -34.1%

DCF figures are point estimates: small changes in growth or discount-rate assumptions move them materially. Read them as a reference, not a precise target.

Ratings Trend (MoM) 100% Bullish
Rating 2026-05 Change
Strong Buy 2 0
Buy 11 0
Hold 0 0
Sell 0 0
Strong Sell 0 0
Price Target Summary
Period # Analysts Avg Target
Last Month 2
41.50
+81.3%
Last Quarter 3
42.67
+86.4%
Last Year 9
35.56
+55.4%
All Time 20
34.65
+51.4%
Quality scores
Altman Z-Score
-1.58
Distress
Piotroski F-Score
2 / 9
Weak
MOAT Score
2 / 10
No MOAT
Composite Rating
D+
Overall Score
1 / 5
Low
DCF Score
1 / 5
Low
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
1 / 5
Low
P/E Score
1 / 5
Low
P/Book Score
1 / 5
Low
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
    +627.8% Q1'26: +223.6% (vs Q1'25)
  • EPS growth Biotechnology: +29.7%
    +11.8% Q1'26: +50.5% (vs Q1'25)
  • FCF margin FCF growth · Biotechnology: +16.2%
    -211.6% Q1'26: -77.6% (vs Q1'25)
  • EBIT margin Biotechnology: +0.0%
    -146.0% Q1'26: -47.5% (vs Q1'25)
  • ROIC Biotechnology: -16.1%
    -1,476.5% Q1'26: -353.1% (vs Q1'25)
  • Share dilution Biotechnology: -3.4%
    +1.2% Q1'26: +1.2% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    -1.38× Q1'26: -2.80× (vs Q1'25)
Valuation Multiples From To
Price Forecast (3Y) From To
Model
Adjust
P/E
Theoretical Return — If Invested Today

* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.

DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (0.41) × ERP
WACC = 84% × Ke + 16% × Kd (9.8%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Intrinsic value (base): 14.87 Current price: 22.89
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2016
actual
Dec 2017
actual
Dec 2018
actual
Dec 2019
actual
Dec 2020
actual
Dec 2021
actual
Dec 2022
actual
Dec 2023
actual
Dec 2024
actual
Dec 2025
actual
Dec 2026
9 Rev. Ana.
9 EPS Ana.
Dec 2027
9 Rev. Ana.
9 EPS Ana.
Dec 2028
11 Rev. Ana.
9 EPS Ana.
Dec 2029
5 Rev. Ana.
3 EPS Ana.
Dec 2030
5 Rev. Ana.
3 EPS Ana.
Revenue
1.22M
est: 1.16M (+5.3%)
2.11M
est: 1.23M (+71.0%)
1.52M
est: 1.60M (-5.0%)
1.52M
est: 1.50M (+1.3%)
1.52M
est: 1.47M (+3.5%)
139.71M
est: 19.15M (+629.6%)
est: 375.0K (-100.0%)
est: 3.50M (-100.0%)
23.68M
est: 48.27M (-50.9%)
172.35M
est: 168.15M (+2.5%)
348.00M
325.83M – 369.70M
+107.0% YoY
513.73M
463.06M – 610.75M
+47.6% YoY
699.40M
681.65M – 717.15M
+36.1% YoY
912.23M
775.89M – 1.18B
+30.4% YoY
1.12B
952.95M – 1.45B
+22.8% YoY
EBITDA
-43.68M
est: 44.6K (-98,078.8%)
-61.88M
est: 47.4K (-130,641.5%)
-73.88M
est: 61.4K (-120,403.2%)
-55.60M
est: 57.6K (-96,614.1%)
-70.29M
est: 56.4K (-124,822.3%)
26.87M
est: 736.6K (+3,547.8%)
-146.17M
est: 14.4K (-1,013,536.9%)
-209.14M
est: 134.6K (-155,457.0%)
-313.82M
est: 1.86M (-17,001.9%)
-251.63M
est: 6.47M (-3,990.8%)
13.39M
12.53M – 14.22M
+107.0% YoY
19.76M
17.81M – 23.49M
+47.6% YoY
26.90M
26.22M – 27.58M
+36.1% YoY
35.09M
29.84M – 45.29M
+30.4% YoY
43.09M
36.65M – 55.62M
+22.8% YoY
EBIT
-43.77M
est: 44.5K (-98,435.1%)
-61.95M
est: 47.3K (-131,011.8%)
-73.96M
est: 61.3K (-120,724.6%)
-56.05M
est: 57.5K (-97,552.7%)
-70.80M
est: 56.3K (-125,937.1%)
26.83M
est: 735.4K (+3,547.8%)
-146.20M
est: 14.4K (-1,015,384.7%)
-209.15M
est: 134.4K (-155,714.4%)
-313.83M
est: 1.85M (-17,029.5%)
-251.64M
est: 6.46M (-3,997.1%)
13.36M
12.51M – 14.20M
+107.0% YoY
19.73M
17.78M – 23.45M
+47.6% YoY
26.86M
26.18M – 27.54M
+36.1% YoY
35.03M
29.80M – 45.21M
+30.4% YoY
43.02M
36.59M – 55.53M
+22.8% YoY
Net Income
-44.47M
est: -305.63M (+85.4%)
-60.80M
est: -242.47M (+74.9%)
-73.96M
est: -251.70M (+70.6%)
-55.96M
est: -156.22M (+64.2%)
-73.07M
est: -159.57M (+54.2%)
24.93M
est: -174.82M (+114.3%)
-149.34M
est: -216.75M (+31.1%)
-209.36M
est: -264.08M (+20.7%)
-318.76M
est: -280.91M (-13.5%)
-285.42M
est: -268.76M (-6.2%)
-143.54M
-241.03M – -108.37M
+46.6% YoY
13.71M
-136.28M – 44.73M
+109.6% YoY
67.56M
49.85M – 85.26M
+392.8% YoY
183.82M
148.10M – 253.29M
+172.1% YoY
267.15M
215.25M – 368.12M
+45.3% YoY
SGA
13.32M
est: 5.13M (+159.8%)
15.86M
est: 5.45M (+190.9%)
17.29M
est: 7.06M (+144.7%)
16.06M
est: 6.63M (+142.4%)
22.51M
est: 6.48M (+247.2%)
25.24M
est: 84.72M (-70.2%)
33.26M
est: 1.66M (+1,904.7%)
66.92M
est: 5.83M (+1,048.0%)
120.88M
est: 80.40M (+50.3%)
179.68M
est: 280.06M (-35.8%)
579.62M
542.69M – 615.76M
+107.0% YoY
855.65M
771.26M – 1.02B
+47.6% YoY
1.16B
1.14B – 1.19B
+36.1% YoY
1.52B
1.29B – 1.96B
+30.4% YoY
1.87B
1.59B – 2.41B
+22.8% YoY
EPS
-3.04
est: -3.57 (+14.8%)
-2.90
est: -2.83 (-2.4%)
-2.92
est: -2.94 (+0.7%)
-1.84
est: -1.82 (-0.8%)
-1.77
est: -1.86 (+5.0%)
0.48
est: -2.04 (+123.5%)
-2.46
est: -2.53 (+2.8%)
-2.98
est: -3.38 (+11.7%)
-3.73
est: -3.48 (-7.3%)
-3.29
est: -3.10 (-6.0%)
-1.80
-2.78 – -1.25
+42.0% YoY
-0.55
-1.57 – 0.52
+69.3% YoY
0.71
0.58 – 0.98
+229.3% YoY
2.12
1.71 – 2.92
+197.1% YoY
3.08
2.48 – 4.25
+45.3% YoY
Recent Grade Changes (3M)
Date Firm Previous New Grade Action
2026-05-01 Barclays Overweight Overweight Maintain
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-11 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-08 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-07 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-06 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-05 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-04 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-01 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-30 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-29 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-28 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-27 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-24 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-23 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-22 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-21 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-20 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-17 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-16 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-15 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
-273.82M
OE per share TTM
-3.17
Owner's Yield
-14.79%
Maintenance CapEx ratio
Maint CapEx / Avg PPE
2.6%

Ownership Overview

Ownership breakdown
At a glance
Institutional holders
38
Total invested
20.27M
Insider transactions (90d)
0
Beneficial owners (>5%)
28
Beneficial owners (>5%)
# Reporting person Amount owned % of class Sole voting Shared voting Sole dispositive Shared dispositive Type Citizenship Filing date SEC filing
1 Wellington Group Holdings LLP 7.98M 11.72% 7.22M HC Massachusetts 2023-01-10
2 Wellington Investment Advisors Holdings LLP 7.98M 11.72% 7.22M HC Massachusetts 2023-01-10
3 Wellington Management Group LLP 7.98M 11.72% 7.22M HC Massachusetts 2023-01-10
4 Wellington Management Company LLP 7.63M 11.21% 7.19M IA Massachusetts 2023-01-10
5 Kynam Capital Management GP, LLC 5.66M 6.67% 5.66M OO Delaware 2024-02-14
6 Kynam Capital Management, LP 5.66M 6.67% 5.66M IA Delaware 2024-02-14
7 Yue Tang 5.66M 6.67% 5.66M IN Delaware 2024-02-14
8 Avidity Capital Partners (GP) LLC 5.24M 9.90% 5.24M 5.24M OO 2022-02-14
9 Avidity Capital Partners Fund (GP) LP 5.24M 9.90% 5.24M 5.24M PN, OO 2022-02-14
10 Avidity Partners Management (GP) LLC 5.24M 9.90% 5.24M 5.24M OO 2022-02-14
11 Avidity Partners Management LP 5.24M 9.90% 5.24M 5.24M IA, PN 2022-02-14
12 David Witzke 5.24M 9.90% 5.24M 5.24M IN 2022-02-14
13 Michael Gregory 5.24M 9.90% 5.24M 5.24M IN 2022-02-14
14 Avidity Master Fund LP 4.51M 8.50% 4.51M 4.51M PN, OO 2022-02-14
15 The Vanguard Group - 23-1945930 4.34M 5.11% 4.16M 178.4K IA Pennsylvania 2024-02-13
16 2 3.52M 5.10% 3.52M IN Delaware 2023-10-31
17 Daniel Mack 3.05M 5.80% 3.05M HC USA 2022-02-14
18 Nantahala Capital Management, LLC 3.05M 5.80% 3.05M IA USA 2022-02-14
19 Wilmot B. Harkey 3.05M 5.80% 3.05M HC MA 2022-02-14
20 AI Life Sciences Investments LLC 2.60M 4.70% 2.60M 2.60M OO 2022-03-04
21 Access Industries Holdings (BVI) L.P. 2.60M 4.70% 2.60M 2.60M PN 2022-03-04
22 Access Industries Holdings LLC 2.60M 4.70% 2.60M 2.60M OO 2022-03-04
23 Access Industries Management, LLC 2.60M 4.70% 2.60M 2.60M OO 2022-03-04
24 Access Industries, LLC 2.60M 4.70% 2.60M 2.60M OO 2022-03-04
25 LSI-SPV 2.60M 4.70% 2.60M 2.60M OO 2022-03-04
26 Len Blavatnik 2.60M 4.70% 2.60M 2.60M IN 2022-03-04
27 Adage Capital Partners GP, L.L.C. 1.20M 2.28% 1.20M OO Delaware 2022-02-10
28 Phillip 1.20M 2.28% 1.20M IN United States 2022-02-10

Institutional Activity (13F)

Institutional ownership trend From To
13F snapshot — 2026 Q1
Investors holding
38
-209 vs prev Q
New positions
10
Closed positions
202
Increased
17
Reduced
12
Put/Call ratio
0.00
Calls held
Puts held
Top institutional holders
# Investor Shares / Δ Mkt value / Δ Own% / Δ Weight% / Δ Avg px / Perf. Hold / Status
1 1.86M +1.9M (+100.0%) 38.97B +39.0B (+100.0%) 2.14% +2.142 pp 11.50% +11.502 pp USD21.01 +0.0% 1 qtrs NEW
2 MACQUARIE MANAGEMENT HOLDINGS, INC. 180.0K +180.0K (+100.0%) 3.78B +3.8B (+100.0%) 0.21% +0.208 pp 0.01% +0.006 pp USD21.01 +0.0% 1 qtrs NEW
3 BLACKROCK, INC. 8.24M -386.2K (-4.5%) 173.10M +40.4M (+30.4%) 9.51% -0.479 pp 0.00% +0.001 pp USD17.01 +23.5% 6 qtrs
4 KYNAM CAPITAL MANAGEMENT, LP 8.05M -469.0K (-5.5%) 169.15M +38.1M (+29.0%) 9.29% -0.574 pp 10.81% +1.046 pp USD18.19 +15.5% 17 qtrs
5 VANGUARD GROUP INC 6.23M +1.1M (+21.2%) 130.90M +51.8M (+65.6%) 7.19% +1.241 pp 0.00% +0.001 pp USD19.05 +10.3% 39 qtrs
6 GOLDMAN SACHS GROUP INC 5.70M +208.9K (+3.8%) 119.66M +35.3M (+41.8%) 6.58% +0.220 pp 0.01% +0.004 pp USD13.20 +59.2% 33 qtrs
7 POINT72 ASSET MANAGEMENT, L.P. 4.88M +627.0K (+14.7%) 102.57M +37.1M (+56.7%) 5.64% +0.708 pp 0.11% +0.005 pp USD16.45 +27.7% 13 qtrs
8 BANK OF AMERICA CORP /DE/ 4.71M +1.0M (+27.4%) 98.97M +42.1M (+74.0%) 5.44% +1.155 pp 0.01% +0.003 pp USD14.11 +48.9% 39 qtrs
9 STATE STREET CORP 4.60M +743.0K (+19.3%) 96.57M +37.3M (+62.9%) 5.31% +0.843 pp 0.00% +0.001 pp USD20.18 +4.1% 39 qtrs
10 EVERSEPT PARTNERS, LP 3.31M -152.9K (-4.4%) 69.64M +16.3M (+30.5%) 3.83% -0.190 pp 3.51% -0.167 pp USD12.96 +62.1% 15 qtrs
11 FRANKLIN RESOURCES INC 2.42M +31.1K (+1.3%) 50.88M +14.1M (+38.3%) 2.80% +0.027 pp 0.01% +0.003 pp USD18.79 +11.8% 9 qtrs
12 KINGDON CAPITAL MANAGEMENT, L.L.C. 2.35M -150.0K (-6.0%) 49.37M +10.9M (+28.4%) 2.71% -0.183 pp 5.87% +1.096 pp USD16.80 +25.1% 9 qtrs
13 HOOD RIVER CAPITAL MANAGEMENT LLC 2.32M +2.3M (+100.0%) 48.67M +48.7M (+100.0%) 2.67% +2.674 pp 0.53% +0.534 pp USD21.01 +0.0% 1 qtrs NEW
14 SOLEUS CAPITAL MANAGEMENT, L.P. 2.25M +235.0K (+11.7%) 47.21M +16.3M (+52.5%) 2.59% +0.264 pp 1.74% +0.183 pp USD15.72 +33.7% 13 qtrs
15 GEODE CAPITAL MANAGEMENT, LLC 2.09M -399.0 (0.0%) 43.94M +11.8M (+36.5%) 2.41% -0.008 pp 0.00% +0.001 pp USD18.85 +11.5% 39 qtrs
16 ENSIGN PEAK ADVISORS, INC 1.60M +789.5K (+97.6%) 33.59M +21.1M (+169.8%) 1.85% +0.908 pp 0.06% +0.039 pp USD18.05 +16.4% 25 qtrs
17 NUVEEN, LLC 1.48M +7.2K (+0.5%) 31.16M +8.5M (+37.2%) 1.71% +0.003 pp 0.01% +0.002 pp USD14.78 +42.2% 4 qtrs
18 BNP PARIBAS ASSET MANAGEMENT HOLDING S.A. 1.38M +139.6K (+11.3%) 28.90M +9.9M (+52.0%) 1.59% +0.157 pp 0.03% -0.016 pp USD16.31 +28.8% 6 qtrs
19 STEMPOINT CAPITAL LP 1.34M -26.8K (-2.0%) 28.14M +7.1M (+33.9%) 1.55% -0.036 pp 4.83% +0.614 pp USD15.19 +38.3% 9 qtrs
20 BIOIMPACT CAPITAL LLC 1.34M -38.0K (-2.8%) 28.11M +6.9M (+32.8%) 1.54% -0.049 pp 3.22% -0.249 pp USD15.39 +36.5% 2 qtrs
21 AISLING CAPITAL MANAGEMENT LP 1.32M +— (+0.0%) 27.67M +7.4M (+36.5%) 1.52% -0.005 pp 5.78% +1.337 pp USD11.05 +90.1% 24 qtrs
22 WOODLINE PARTNERS LP 1.25M -299.9K (-19.3%) 26.28M +2.4M (+10.2%) 1.44% -0.352 pp 0.10% -0.011 pp USD21.16 -0.7% 11 qtrs
23 EVENTIDE ASSET MANAGEMENT, LLC 1.24M +249.7K (+25.3%) 26.01M +10.8M (+71.1%) 1.43% +0.285 pp 0.41% +0.156 pp USD16.96 +23.9% 6 qtrs
24 D. E. SHAW & CO., INC. 1.22M +142.0K (+13.2%) 25.62M +9.0M (+54.6%) 1.41% +0.160 pp 0.01% +0.005 pp USD15.39 +36.5% 14 qtrs
25 CATALIO CAPITAL MANAGEMENT, LP 1.20M -417.9K (-25.9%) 25.14M +302.5K (+1.2%) 1.38% -0.489 pp 4.44% -0.148 pp USD11.78 +78.4% 4 qtrs
26 TWO SIGMA INVESTMENTS, LP 1.15M +434.3K (+60.9%) 24.10M +13.1M (+119.8%) 1.32% +0.499 pp 0.03% +0.018 pp USD18.70 +12.4% 12 qtrs
27 BANK OF NEW YORK MELLON CORP 1.09M +41.8K (+4.0%) 22.99M +6.8M (+42.0%) 1.26% +0.044 pp 0.00% +0.001 pp USD16.03 +31.1% 38 qtrs
28 MORGAN STANLEY 1.08M -123.8K (-10.3%) 22.60M +4.1M (+22.5%) 1.24% -0.148 pp 0.00% +0.000 pp USD14.75 +42.4% 40 qtrs
29 ALGERT GLOBAL LLC 928.1K -2.7K (-0.3%) 19.50M +5.2M (+36.2%) 1.07% -0.007 pp 0.30% +0.064 pp USD15.23 +38.0% 17 qtrs
30 AQR CAPITAL MANAGEMENT LLC 926.0K +367.9K (+65.9%) 19.45M +10.9M (+126.6%) 1.07% +0.423 pp 0.01% +0.005 pp USD17.02 +23.4% 16 qtrs
31 CANDRIAM S.C.A. 925.3K +— (+0.0%) 19.44M +5.2M (+36.6%) 1.07% -0.004 pp 0.10% +0.022 pp USD16.89 +24.4% 12 qtrs
32 PALO ALTO INVESTORS LP 794.5K +139.6K (+21.3%) 16.69M +6.6M (+65.7%) 0.92% +0.159 pp 2.32% +0.459 pp USD17.48 +20.2% 24 qtrs
33 SPHERA FUNDS MANAGEMENT LTD. 762.6K +374.8K (+96.7%) 16.02M +10.1M (+168.6%) 0.88% +0.431 pp 3.10% +1.839 pp USD18.81 +11.7% 24 qtrs
34 JANE STREET GROUP, LLC 748.9K +10.7K (+1.4%) 15.73M +4.4M (+38.5%) 0.86% +0.010 pp 0.00% +0.001 pp USD14.58 +44.1% 13 qtrs
35 NORTHERN TRUST CORP 728.9K -47.8K (-6.1%) 15.31M +3.4M (+28.2%) 0.84% -0.058 pp 0.00% +0.000 pp USD16.57 +26.8% 39 qtrs
36 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 727.4K +8.4K (+1.2%) 15.28M +4.2M (+38.2%) 0.84% +0.007 pp 0.00% +0.001 pp USD18.68 +12.5% 39 qtrs
37 APIS CAPITAL ADVISORS, LLC 724.0K +86.0K (+13.5%) 15.21M +5.4M (+55.0%) 0.84% +0.097 pp 2.65% +0.482 pp USD16.06 +30.8% 2 qtrs
38 UBS GROUP AG 716.2K -958.3K (-57.2%) 15.05M -10.7M (-41.6%) 0.83% -1.113 pp 0.00% -0.002 pp USD13.77 +52.6% 39 qtrs
39 QUBE RESEARCH & TECHNOLOGIES LTD 688.1K -956.7K (-58.2%) 14.46M -10.8M (-42.9%) 0.79% -1.111 pp 0.01% -0.012 pp USD14.07 +49.3% 12 qtrs
40 PROSIGHT MANAGEMENT, LP 665.0K -338.4K (-33.7%) 13.97M -1.5M (-9.5%) 0.77% -0.395 pp 2.89% -0.713 pp USD15.73 +33.6% 7 qtrs
41 SILVERARC CAPITAL MANAGEMENT, LLC 642.9K +179.2K (+38.6%) 13.51M +6.4M (+89.3%) 0.74% +0.205 pp 1.88% +0.914 pp USD17.06 +23.2% 7 qtrs
42 TWO SIGMA ADVISERS, LP 632.8K +249.7K (+65.2%) 13.29M +7.4M (+125.6%) 0.73% +0.287 pp 0.03% +0.014 pp USD21.71 -3.2% 25 qtrs
43 PARKMAN HEALTHCARE PARTNERS LLC 574.0K -272.9K (-32.2%) 12.06M -969.3K (-7.4%) 0.66% -0.318 pp 1.15% -0.211 pp USD16.80 +25.1% 11 qtrs
44 EXODUSPOINT CAPITAL MANAGEMENT, LP 554.8K +482.3K (+665.6%) 11.66M +10.5M (+945.5%) 0.64% +0.557 pp 0.09% +0.080 pp USD20.28 +3.6% 16 qtrs
45 RENAISSANCE TECHNOLOGIES LLC 544.8K -315.7K (-36.7%) 11.45M -1.8M (-13.5%) 0.63% -0.368 pp 0.02% +0.000 pp USD12.58 +67.0% 10 qtrs
46 BREVAN HOWARD CAPITAL MANAGEMENT LP 515.1K +390.6K (+313.5%) 10.82M +8.9M (+464.9%) 0.59% +0.450 pp 0.12% +0.110 pp USD19.57 +7.4% 6 qtrs
47 RHENMAN & PARTNERS ASSET MANAGEMENT AB 487.0K -87.0K (-15.2%) 10.23M +1.4M (+15.9%) 0.56% -0.103 pp 0.96% -0.021 pp USD15.82 +32.8% 8 qtrs
48 SUSQUEHANNA INTERNATIONAL GROUP, LLP 434.1K +21.1K (+5.1%) 9.12M +2.8M (+43.5%) 0.50% +0.023 pp 0.00% +0.000 pp USD15.76 +33.3% 32 qtrs
49 CAPTION MANAGEMENT, LLC 424.5K -194.3K (-31.4%) 8.92M -601.5K (-6.3%) 0.49% -0.227 pp 0.06% -0.013 pp USD13.20 +59.2% 6 qtrs
50 KNOTT DAVID M JR 415.0K -13.0K (-3.0%) 8.72M +2.1M (+32.4%) 0.48% -0.017 pp 4.04% +1.382 pp USD14.20 +48.0% 8 qtrs
51 JPMORGAN CHASE & CO 378.5K +124.7K (+49.1%) 7.95M +4.0M (+103.6%) 0.44% +0.143 pp 0.00% +0.000 pp USD18.28 +14.9% 39 qtrs
52 ABRDN PLC 372.8K +— (+0.0%) 7.83M +2.1M (+36.6%) 0.43% -0.001 pp 0.01% +0.003 pp USD11.78 +78.4% 5 qtrs
53 GRANAHAN INVESTMENT MANAGEMENT, LLC 366.8K -29.5K (-7.5%) 7.71M +1.6M (+26.4%) 0.42% -0.036 pp 0.33% +0.080 pp USD14.91 +40.9% 9 qtrs
54 BARCLAYS PLC 314.7K +127.0K (+67.7%) 6.61M +3.0M (+83.0%) 0.36% +0.146 pp 0.00% +0.001 pp USD16.96 +23.9% 39 qtrs
55 PALE FIRE CAPITAL SE 284.5K +284.5K (+100.0%) 5.98M +6.0M (+100.0%) 0.33% +0.328 pp 0.40% +0.401 pp USD21.01 +0.0% 1 qtrs NEW
56 AMERIPRISE FINANCIAL INC 282.6K +187.1K (+196.1%) 5.94M +4.5M (+304.3%) 0.33% +0.216 pp 0.00% +0.001 pp USD18.20 +15.4% 11 qtrs
57 DAFNA CAPITAL MANAGEMENT LLC 277.9K -222.8K (-44.5%) 5.84M -1.9M (-24.2%) 0.32% -0.259 pp 1.36% -0.547 pp USD21.10 -0.4% 23 qtrs
58 SECTOR GAMMA AS 252.1K +41.2K (+19.6%) 5.30M +2.1M (+63.3%) 0.29% +0.047 pp 1.21% +0.403 pp USD16.31 +28.8% 2 qtrs
59 PFM HEALTH SCIENCES, LP 243.0K -13.5K (-5.3%) 5.10M +1.2M (+29.4%) 0.28% -0.017 pp 0.51% +0.206 pp USD15.39 +36.5% 20 qtrs
60 CAPITAL FUND MANAGEMENT S.A. 233.9K -107.3K (-31.5%) 4.91M -335.6K (-6.4%) 0.27% -0.125 pp 0.01% 0.000 pp USD12.24 +71.7% 3 qtrs
61 CANADA PENSION PLAN INVESTMENT BOARD 229.6K +— (+0.0%) 4.82M +1.3M (+36.6%) 0.27% -0.001 pp 0.00% +0.001 pp USD15.39 +36.5% 2 qtrs
62 VIENNA POWSZECHNE TOWARZYSTWO EMERYTALNE S.A. VIENNA INSURANCE GROUP 200.0K +— (+0.0%) 4.20M +1.1M (+36.6%) 0.23% -0.001 pp 2.05% +0.233 pp USD12.29 +71.0% 4 qtrs
63 INTEGRAL HEALTH ASSET MANAGEMENT, LLC 200.0K +200.0K (+100.0%) 4.20M +4.2M (+100.0%) 0.23% +0.231 pp 0.21% +0.209 pp USD21.01 +0.0% 1 qtrs NEW
64 HENNION & WALSH ASSET MANAGEMENT, INC. 183.8K +129.1K (+236.0%) 3.86M +3.0M (+358.9%) 0.21% +0.149 pp 0.13% +0.103 pp USD18.28 +14.9% 3 qtrs
65 HUDSON BAY CAPITAL MANAGEMENT LP 165.0K -85.0K (-34.0%) 3.47M -379.6K (-9.9%) 0.19% -0.099 pp 0.01% -0.001 pp USD14.94 +40.6% 6 qtrs
66 JUMP FINANCIAL, LLC 163.9K +31.2K (+23.5%) 3.44M +1.4M (+68.7%) 0.19% +0.036 pp 0.04% +0.018 pp USD11.59 +81.3% 7 qtrs
67 RAFFERTY ASSET MANAGEMENT, LLC 161.9K +20.1K (+14.2%) 3.40M +1.2M (+55.9%) 0.19% +0.023 pp 0.01% +0.005 pp USD21.60 -2.7% 22 qtrs
68 SWISS NATIONAL BANK 161.4K +2.9K (+1.8%) 3.39M +952.5K (+39.1%) 0.19% +0.003 pp 0.00% +0.001 pp USD20.64 +1.8% 21 qtrs
69 WELLS FARGO & COMPANY/MN 160.9K +103.9K (+182.6%) 3.38M +2.5M (+285.9%) 0.19% +0.120 pp 0.00% +0.000 pp USD17.86 +17.6% 38 qtrs
70 INVESCO LTD. 160.5K +27.4K (+20.6%) 3.37M +1.3M (+64.7%) 0.19% +0.031 pp 0.00% +0.000 pp USD16.73 +25.6% 24 qtrs
71 SEI INVESTMENTS CO 159.6K +116.2K (+267.4%) 3.35M +2.7M (+401.8%) 0.18% +0.134 pp 0.00% +0.003 pp USD19.59 +7.2% 14 qtrs
72 Y-INTERCEPT (HONG KONG) LTD 155.9K +55.1K (+54.6%) 3.28M +1.7M (+111.1%) 0.18% +0.063 pp 0.07% +0.036 pp USD13.48 +55.9% 7 qtrs
73 UBS ASSET MANAGEMENT AMERICAS INC 142.4K +8.1K (+6.1%) 2.99M +926.4K (+44.8%) 0.16% +0.009 pp 0.00% +0.000 pp USD16.63 +26.3% 21 qtrs
74 ATOM INVESTORS LP 141.7K +141.7K (+100.0%) 2.98M +3.0M (+100.0%) 0.16% +0.164 pp 0.24% +0.236 pp USD21.01 +0.0% 5 qtrs
75 FMR LLC 140.6K +135.5K (+2,655.5%) 2.95M +2.9M (+3,663.1%) 0.16% +0.156 pp 0.00% +0.000 pp USD20.78 +1.1% 17 qtrs
76 HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND 137.6K +137.6K (+100.0%) 2.89M +2.9M (+100.0%) 0.16% +0.159 pp 0.00% +0.005 pp USD21.01 +0.0% 11 qtrs
77 CITADEL ADVISORS LLC 137.2K +29.6K (+27.5%) 2.88M +1.2M (+74.1%) 0.16% +0.034 pp 0.00% +0.000 pp USD15.86 +32.5% 31 qtrs
78 VELAN CAPITAL INVESTMENT MANAGEMENT LP 130.0K +— (+0.0%) 2.73M +731.3K (+36.6%) 0.15% -0.001 pp 1.58% -0.294 pp USD15.39 +36.5% 2 qtrs
79 SG AMERICAS SECURITIES, LLC 129.2K +83.8K (+184.5%) 2.72M +2.0M (+288.4%) 0.15% +0.097 pp 0.00% +0.001 pp USD19.03 +10.4% 2 qtrs
80 PANAGORA ASSET MANAGEMENT INC 125.1K -30.2K (-19.5%) 2.63M +238.8K (+10.0%) 0.14% -0.036 pp 0.01% 0.000 pp USD15.39 +36.5% 2 qtrs
81 VOSS CAPITAL, LLC 125.0K +125.0K (+100.0%) 2.63M +2.6M (+100.0%) 0.14% +0.144 pp 0.13% +0.126 pp USD21.01 +0.0% 1 qtrs NEW
82 RHUMBLINE ADVISERS 118.8K -12.9K (-9.8%) 2.50M +470.2K (+23.2%) 0.14% -0.015 pp 0.00% +0.000 pp USD16.96 +23.9% 31 qtrs
83 YELIN LAPIDOT HOLDINGS MANAGEMENT LTD. 108.4K +— (+0.0%) 2.28M +609.6K (+36.6%) 0.13% 0.000 pp 0.46% +0.106 pp USD14.52 +44.7% 10 qtrs
84 NEOS INVESTMENT MANAGEMENT LLC 101.6K -8.5K (-7.7%) 2.13M +440.3K (+26.0%) 0.12% -0.010 pp 0.01% 0.000 pp USD11.23 +87.1% 4 qtrs
85 TEMA ETFS LLC 100.1K -10.0K (-9.1%) 2.10M +408.7K (+24.1%) 0.12% -0.012 pp 0.16% +0.023 pp USD11.23 +87.1% 4 qtrs
86 IEQ CAPITAL, LLC 99.9K +44.7K (+80.9%) 2.10M +1.2M (+147.1%) 0.12% +0.051 pp 0.01% +0.004 pp USD17.50 +20.1% 4 qtrs
87 TORRAY INVESTMENT PARTNERS LLC 97.8K +97.8K (+100.0%) 2.05M +2.1M (+100.0%) 0.11% +0.113 pp 0.29% +0.294 pp USD21.01 +0.0% 1 qtrs NEW
88 ALLIANCEBERNSTEIN L.P. 94.9K -31.8K (-25.1%) 1.99M +44.9K (+2.3%) 0.11% -0.037 pp 0.00% +0.000 pp USD16.19 +29.8% 33 qtrs
89 PRICE T ROWE ASSOCIATES INC /MD/ 94.8K +3.7K (+4.1%) 1.99M +591.0K (+42.2%) 0.11% +0.004 pp 0.00% +0.000 pp USD18.19 +15.5% 14 qtrs
90 RUSSELL INVESTMENTS GROUP, LTD. 89.6K +10.1K (+12.7%) 1.88M +659.6K (+53.9%) 0.10% +0.011 pp 0.00% +0.001 pp USD13.77 +52.6% 13 qtrs
91 TREXQUANT INVESTMENT LP 87.5K +87.5K (+100.0%) 1.84M +1.8M (+100.0%) 0.10% +0.101 pp 0.02% +0.016 pp USD21.01 +0.0% 1 qtrs NEW
92 LEGAL & GENERAL GROUP PLC 78.2K -6.3K (-7.5%) 1.64M +343.0K (+26.4%) 0.09% -0.008 pp 0.00% +0.000 pp USD20.39 +3.0% 37 qtrs
93 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 78.2K -88.0 (-0.1%) 1.64M +438.5K (+36.4%) 0.09% 0.000 pp 0.00% +0.000 pp USD16.62 +26.4% 39 qtrs
94 STIFEL FINANCIAL CORP 75.9K -22.4K (-22.8%) 1.59M +82.0K (+5.4%) 0.09% -0.026 pp 0.00% +0.000 pp USD13.54 +55.2% 6 qtrs
95 DARK FOREST CAPITAL MANAGEMENT LP 72.7K -87.6K (-54.7%) 1.53M +26.0K (+1.7%) 0.08% -0.102 pp 0.07% +0.025 pp USD10.08 +108.4% 4 qtrs
Ownership breakdown by holder

Insider Activity

Insider Activity — Latest Quarter
Ratio by transactions
4.00
Bullish
Ratio by volume
3.00
Bullish
Buys
16
Sells
4
Shares acquired
1.20M
Shares disposed
30.1K
Cash buys
Cash sales
4.00
Net activity
+1,171,706
Insider buys vs sells (history) From To
Recent insider transactions From To
Date Person Role Transaction A/D Security Shares Price Value Owned after D/I Filing
2026-02-09 Metzger Michael A Director / Officer S-Sale D Common Stock 17,159 21.03 360.8K 491,690 D
2026-02-09 Goldan Keith A. Officer S-Sale D Common Stock 3,410 21.03 71.7K 140,429 D
2026-02-06 Metzger Michael A Director / Officer S-Sale D Common Stock 7,412 20.62 152.8K 508,849 D
2026-02-06 Goldan Keith A. Officer S-Sale D Common Stock 2,082 20.62 42.9K 143,839 D
2026-02-04 Rizo Aleksandra Director A-Award A Common Stock 24,000 0.00 49,000 D
2026-02-04 Podlesak Dennis Director A-Award A Common Stock 48,000 0.00 239,763 D
2026-02-04 Metzger Michael A Director / Officer A-Award A Common Stock 73,000 0.00 371,661 D
2026-02-04 Legault Pierre Director A-Award A Common Stock 24,000 0.00 114,000 D
2026-02-04 Katkin Keith Director A-Award A Common Stock 24,000 0.00 124,000 D
2026-02-04 Jarrett Jennifer Director A-Award A Common Stock 24,000 0.00 114,000 D
2026-02-04 Huber Martin H. Jr. Director A-Award A Common Stock 24,000 0.00 103,000 D
2026-02-04 Goldan Keith A. Officer A-Award A Common Stock 21,500 0.00 115,171 D
2026-02-04 Botwood Nicholas A.J. Officer A-Award A Common Stock 24,000 0.00 59,165 D
2026-01-30 Goldan Keith A. Officer J-Other A Common Stock 1,219 8.48 10.3K 93,671 D
2025-12-01 Goldan Keith A. Officer G-Gift D Common Stock 1,224 0.00 92,452 D
2025-09-08 Metzger Michael A Director / Officer M-Exempt A Common Stock 157,307 10.90 1.71M 455,968 D
2025-08-18 Podlesak Dennis Director M-Exempt D Stock Options (Right to buy) 19,200 7.20 138.2K 0 D
2025-08-15 Podlesak Dennis Director S-Sale D Common Stock 19,200 15.54 298.4K 191,763 D
2025-08-14 Podlesak Dennis Director S-Sale D Common Stock 19,200 14.19 272.5K 191,763 D
2025-07-31 Goldan Keith A. Officer J-Other A Common Stock 1,226 8.43 10.3K 93,676 D
2025-07-16 Metzger Michael A Director / Officer S-Sale D Common Stock 7,534 9.29 70.0K 298,661 D
2025-07-16 Goldan Keith A. Officer S-Sale D Common Stock 1,296 9.29 12.0K 92,450 D
2025-05-19 Katkin Keith Director P-Purchase A Common Stock 10,000 9.11 91.1K 100,000 D
2025-05-19 Huber Martin H. Jr. Director P-Purchase A Common Stock 5,000 8.99 45.0K 79,000 D
2025-05-19 Goldan Keith A. Officer P-Purchase A Common Stock 3,000 0.00 93,746 D
2025-05-16 Botwood Nicholas A.J. Officer P-Purchase A Common Stock 11,765 9.00 105.8K 35,165 D
2025-05-12 Botwood Nicholas A.J. Officer Common Stock 0 0.00 23,400 D
2025-03-14 Metzger Michael A Director / Officer M-Exempt A Common Stock 6,074 7.20 43.7K 306,195 D
2025-03-04 Metzger Michael A Director / Officer S-Sale D Common Stock 7,814 15.05 117.6K 300,121 D
2025-02-10 Metzger Michael A Director / Officer S-Sale D Common Stock 13,288 15.50 206.0K 300,121 D
2025-02-10 Goldan Keith A. Officer S-Sale D Common Stock 3,777 15.50 58.6K 90,746 D
2025-02-10 Gallagher Neil Officer S-Sale D Common Stock 4,618 15.50 71.6K 85,095 D
2025-02-05 Rizo Aleksandra Director A-Award A Common Stock 25,000 0.00 25,000 D
2025-02-05 Podlesak Dennis Director A-Award A Common Stock 50,000 0.00 191,763 D
2025-02-05 Meury William Director A-Award A Common Stock 25,000 0.00 90,000 D
2025-02-05 Metzger Michael A Director / Officer A-Award A Common Stock 89,000 0.00 313,409 D
2025-02-05 Legault Pierre Director A-Award A Common Stock 25,000 0.00 90,000 D
2025-02-05 Katkin Keith Director A-Award A Common Stock 25,000 0.00 90,000 D
2025-02-05 Jarrett Jennifer Director A-Award A Common Stock 25,000 0.00 90,000 D
2025-02-05 Huber Martin H. Jr. Director A-Award A Common Stock 25,000 0.00 74,000 D
2025-02-05 Goldan Keith A. Officer A-Award A Common Stock 18,500 0.00 71,123 D
2025-02-05 Gallagher Neil Officer A-Award A Stock Options (Right to buy) 110,500 14.65 1.62M 110,500 D
2024-06-14 Goldan Keith A. Officer P-Purchase A Common Stock 1,250 20.03 25.0K 52,623
2024-05-15 Rizo Aleksandra Director A-Award A Stock Options (Right to buy) 35,000 21.94 767.9K 35,000
2024-02-07 Podlesak Dennis Director A-Award A Common Stock 34,000 0.00 141,763
2024-02-07 Morrison Briggs Director A-Award A Common Stock 17,000 0.00 34,836
2024-02-07 Meury William Director A-Award A Common Stock 17,000 0.00 65,000
2024-02-07 Metzger Michael A Director / Officer A-Award A Common Stock 107,250 0.00 124,909
2024-02-07 Legault Pierre Director A-Award A Common Stock 17,000 0.00 65,000
2024-02-07 Katkin Keith Director A-Award A Common Stock 17,000 0.00 65,000
2024-02-07 Jarrett Jennifer Director A-Award A Common Stock 17,000 0.00 65,000
2024-02-07 Huber Martin H. Jr. Director A-Award A Common Stock 17,000 0.00 49,000
2024-02-07 Goldan Keith A. Officer A-Award A Common Stock 35,000 0.00 39,673
2024-02-07 Gallagher Neil Officer A-Award A Common Stock 34,688 0.00 34,688
2024-01-31 Goldan Keith A. Officer J-Other A Common Stock 1,183 17.42 20.6K 4,673
2023-08-09 Morrison Briggs Director M-Exempt A Common Stock 52,855 8.77 463.5K 70,691
2023-08-02 Meury William Director M-Exempt A Common Stock 35,000 7.11 248.9K 83,000
2023-07-31 Goldan Keith A. Officer J-Other A Common Stock 862 18.12 15.6K 3,490
2023-07-10 Morrison Briggs Director S-Sale D Common Stock 52,855 20.40 1.08M 17,836
2023-06-13 Goldan Keith A. Officer S-Sale D Common Stock 577 22.31 12.9K 2,628
2023-06-09 Morrison Briggs Director M-Exempt A Common Stock 28,273 8.77 248.0K 70,691
2023-05-09 Morrison Briggs Director M-Exempt A Common Stock 52,855 6.38 337.2K 70,691
2023-04-10 Morrison Briggs Director M-Exempt D Stock Options (Right to buy) 52,855 6.38 337.2K 0
2023-04-10 Gallagher Neil Officer A-Award A Stock Options (Right to buy) 250,000 19.35 4.84M 250,000
2023-03-13 Morrison Briggs M-Exempt A Common Stock 52,854 6.38 337.2K 70,690
2023-02-15 Ordentlich Peter M-Exempt A Common Stock 17,428 7.20 125.5K 17,428
2023-02-06 Morrison Briggs S-Sale D Common Stock 52,854 26.83 1.42M 17,836
2023-02-06 Metzger Michael A M-Exempt D Stock Options (Right to buy) 5,959 6.38 38.0K 0
2023-02-02 Podlesak Dennis A-Award A Common Stock 32,000 0.00 107,763
2023-02-02 Ordentlich Peter A-Award A Stock Options (Right to buy) 90,000 28.55 2.57M 90,000
2023-02-02 Nolte Alexander A-Award A Stock Options (Right to buy) 17,000 28.55 485.4K 17,000
2023-02-02 Morrison Briggs A-Award A Stock Options (Right to buy) 32,000 28.55 913.6K 32,000
2023-02-02 Meury William A-Award A Common Stock 16,000 0.00 48,000
2023-02-02 Metzger Michael A A-Award A Stock Options (Right to buy) 410,000 28.55 11.71M 410,000
2023-02-02 Madigan Catherine A-Award A Stock Options (Right to buy) 110,000 28.55 3.14M 110,000
2023-02-02 Legault Pierre A-Award A Common Stock 16,000 0.00 48,000
2023-02-02 Katkin Keith A-Award A Common Stock 16,000 0.00 48,000
2023-02-02 Jarrett Jennifer A-Award A Common Stock 16,000 0.00 48,000
2023-02-02 Huber Martin H. Jr. A-Award A Common Stock 16,000 0.00 32,000
2023-02-02 Goldan Keith A. A-Award A Stock Options (Right to buy) 110,000 28.55 3.14M 110,000
2023-02-01 Ordentlich Peter S-Sale D Common Stock 69 28.43 2.0K 0
2023-01-31 Ordentlich Peter J-Other A Common Stock 69 17.32 1.2K 69
2023-01-13 Legault Pierre Director M-Exempt A Common Stock 5,000 13.58 67.9K 37,000
2023-01-12 Legault Pierre Director M-Exempt A Common Stock 24,000 9.47 227.3K 56,000
2022-12-05 Sabus Steve M Director / Officer A-Award A Stock Options (Right to buy) 220,000 25.44 5.60M 220,000
2022-12-02 Ordentlich Peter Director / Officer M-Exempt A Common Stock 17,200 6.38 109.7K 17,465
2022-12-01 Ordentlich Peter Director / Officer M-Exempt A Common Stock 4,028 6.38 25.7K 4,293
2022-10-06 Metzger Michael A Director / Officer M-Exempt D Stock Options (Right to buy) 16,231 0.00 0
2022-10-06 Katkin Keith Director M-Exempt D Stock Options (Right to buy) 20,782 0.00 0
2022-10-04 Metzger Michael A Director / Officer M-Exempt A Common Stock 1,280 8.77 11.2K 18,939
2022-10-04 Katkin Keith Director M-Exempt A Common Stock 137 7.88 1.1K 32,137
2022-10-03 Metzger Michael A Director / Officer M-Exempt A Common Stock 2,883 8.77 25.3K 20,542
2022-10-03 Katkin Keith Director M-Exempt A Common Stock 13 8.93 116.09 32,013
2022-09-30 Metzger Michael A Director / Officer M-Exempt A Common Stock 29,606 8.77 259.6K 47,265
2022-09-30 Katkin Keith Director M-Exempt A Common Stock 2,914 7.88 23.0K 34,914
2022-09-20 Morrison Briggs Director / Officer M-Exempt A Common Stock 59,649 10.90 650.2K 77,485
2022-09-19 Morrison Briggs Director / Officer M-Exempt A Common Stock 114,339 10.90 1.25M 132,175
2022-09-16 Podlesak Dennis Director M-Exempt D Stock Options (Right to buy) 5,419 6.32 34.2K 0
2022-09-16 Morrison Briggs Director / Officer M-Exempt D Stock Options (Right to buy) 71,966 7.20 518.2K 0
2022-09-15 Podlesak Dennis Director M-Exempt A Common Stock 66,840 6.32 422.4K 142,603
2022-09-15 Morrison Briggs Director / Officer M-Exempt A Common Stock 66,775 7.20 480.8K 84,611
2022-09-14 Morrison Briggs Director / Officer S-Sale D Common Stock 87,645 23.80 2.09M 17,836
2022-08-24 Ordentlich Peter Officer M-Exempt A Common Stock 2,154 6.35 13.7K 2,419
2022-08-05 Legault Pierre Director M-Exempt A Common Stock 14,000 8.93 125.0K 46,000
2022-07-29 Ordentlich Peter Director / Officer J-Other A Common Stock 265 14.12 3.7K 265
2022-07-25 Metzger Michael A Director / Officer S-Sale D Common Stock 19,764 21.06 416.1K 17,659
2022-07-06 Metzger Michael A Director / Officer S-Sale D Common Stock 100 21.00 2.1K 17,659
2022-07-01 Morrison Briggs Director S-Sale D Common Stock 62,292 19.00 1.18M 17,836
2022-06-13 Goldan Keith A. Director / Officer A-Award A Stock Options (Right to buy) 230,000 15.60 3.59M 230,000
2022-04-04 Morrison Briggs Director / Officer M-Exempt D Stock Options (Right to buy) 3,128 10.90 34.1K 0
2022-04-01 Morrison Briggs Director M-Exempt A Common Stock 3,128 10.90 34.1K 20,964
2022-03-01 Madigan Catherine A-Award A Stock Options (Right to buy) 180,000 16.06 2.89M 180,000
2022-02-02 Podlesak Dennis A-Award A Common Stock 32,000 0.00 75,763
2022-02-02 Ordentlich Peter A-Award A Stock Options (Right to buy) 80,000 15.79 1.26M 80,000
2022-02-02 Nolte Alexander A-Award A Stock Options (Right to buy) 30,000 15.79 473.7K 30,000
2022-02-02 Morrison Briggs A-Award A Stock Options (Right to buy) 160,000 15.79 2.53M 160,000
2022-02-02 Meyers Michael L. A-Award A Stock Options (Right to buy) 17,350 15.79 274.0K 17,350
2022-02-02 Meury William A-Award A Common Stock 16,000 0.00 32,000
2022-02-02 Metzger Michael A A-Award A Stock Options (Right to buy) 325,000 15.79 5.13M 325,000
2022-02-02 Legault Pierre A-Award A Common Stock 16,000 0.00 32,000
2022-02-02 Katkin Keith Director A-Award A Common Stock 16,000 0.00 32,000
2022-02-02 Jarrett Jennifer A-Award A Common Stock 16,000 0.00 32,000
2022-02-02 Huber Martin H. Jr. A-Award A Common Stock 16,000 0.00 16,000
2022-02-02 Egros Fabrice A-Award A Common Stock 16,000 0.00 32,000
2022-02-01 Ordentlich Peter S-Sale D Common Stock 1,412 16.65 23.5K 0
2022-02-01 Nolte Alexander S-Sale D Common Stock 968 16.65 16.1K 0
2022-01-31 Ordentlich Peter J-Other A Common Stock 1,412 12.39 17.5K 1,412
2022-01-31 Nolte Alexander J-Other A Common Stock 968 12.39 12.0K 968
2022-01-31 Meyers Michael L. J-Other A Common Stock 1,714 12.39 21.2K 23,280
2021-12-30 Meyers Michael L. M-Exempt A Common Stock 5,900 8.77 51.7K 21,566
2021-12-22 Legault Pierre S-Sale D Common Stock 24,000 22.01 528.2K 16,000
2021-12-20 Metzger Michael A M-Exempt A Common Stock 45,000 8.77 394.7K 62,659
2021-12-20 Legault Pierre M-Exempt A Common Stock 20,000 7.08 141.6K 36,000
2021-12-17 Morrison Briggs Director / Officer S-Sale D Common Stock 35,156 20.00 703.1K 48,336
2021-12-17 Metzger Michael A S-Sale D Common Stock 1,676 19.02 31.9K 17,659
2021-12-16 Metzger Michael A M-Exempt A Common Stock 22,715 6.38 144.9K 40,374
2021-12-13 Metzger Michael A S-Sale D Common Stock 34,564 19.05 658.6K 17,659
2021-11-18 Egros Fabrice S-Sale D Common Stock 30 18.03 540.97 16,000
2021-10-26 Metzger Michael A M-Exempt A Common Stock 16,296 7.20 117.3K 33,955
2021-10-25 Metzger Michael A M-Exempt A Common Stock 44,704 7.20 321.9K 62,363
2021-10-22 Nolte Alexander D Stock Options (Right to buy) 35,000 19.36 677.6K 0
2021-10-05 Podlesak Dennis J-Other A Common Stock 463 0.00 43,763
2021-09-27 Metzger Michael A M-Exempt A Common Stock 24,437 7.20 175.9K 42,096
2021-09-22 Metzger Michael A M-Exempt D Stock Options (Right to buy) 300 7.20 2.2K 0
2021-09-21 Metzger Michael A M-Exempt A Common Stock 4,808 7.20 34.6K 22,467
2021-09-20 Morrison Briggs M-Exempt D Stock Options (Right to buy) 50 7.20 360.00 0
2021-09-20 Metzger Michael A S-Sale D Common Stock 31,455 19.24 605.0K 17,659
2021-09-17 Morrison Briggs M-Exempt A Common Stock 70,262 7.20 505.9K 118,598
2021-09-15 Huber Martin H. Jr. A-Award A Stock Options (Right to buy) 35,000 19.36 677.6K 35,000
2021-09-14 Metzger Michael A M-Exempt A Common Stock 44,349 7.20 319.3K 62,008
2021-09-13 Metzger Michael A S-Sale D Common Stock 16,651 19.02 316.6K 17,659
2021-08-18 Egros Fabrice M-Exempt A Common Stock 15,635 7.88 123.2K 31,635
2021-05-18 Egros Fabrice S-Sale D Common Stock 1,683 18.65 31.4K 16,000
2021-04-26 Meyers Michael L. Officer P-Purchase A Common Stock 500 15.46 7.7K 15,666
2021-04-22 Podlesak Dennis P-Purchase A Common Stock 13,967 14.11 197.1K 43,300
2021-03-01 Egros Fabrice M-Exempt A Common Stock 74 7.20 532.80 26,241
2021-02-08 Morrison Briggs S-Sale D Common Stock 35,156 20.55 722.4K 48,336
2021-02-03 Podlesak Dennis A-Award A Common Stock 29,333 0.00 29,333
2021-02-03 Ordentlich Peter A-Award A Stock Option (Right to Buy) 80,000 21.36 1.71M 80,000
2021-02-03 Morrison Briggs A-Award A Stock Option (Right to Buy) 195,000 21.36 4.17M 195,000
2021-02-03 Meyers Michael L. Director / Officer A-Award A Stock Option (Right to Buy) 80,000 21.36 1.71M 80,000
2021-02-03 Meury William A-Award A Common Stock 16,000 0.00 16,000
2021-02-03 Metzger Michael A A-Award A Stock Option (Right to Buy) 160,000 21.36 3.42M 160,000
2021-02-03 Legault Pierre A-Award A Common Stock 16,000 0.00 16,000
2021-02-03 Katkin Keith A-Award A Common Stock 16,000 0.00 16,000
2021-02-03 Karydas Daphne A-Award A Stock Option (Right to Buy) 95,000 21.36 2.03M 95,000
2021-02-03 Jarrett Jennifer A-Award A Common Stock 16,000 0.00 16,000
2021-02-03 Egros Fabrice A-Award A Common Stock 16,000 0.00 16,000
2021-02-01 Metzger Michael A M-Exempt D Stock Options (Right to buy) 15,000 7.20 108.0K 0
2021-01-31 Morrison Briggs J-Other A Common Stock 1,771 12.00 21.3K 48,336
2021-01-31 Meyers Michael L. Officer J-Other A Common Stock 1,771 12.00 21.3K 15,166
2020-12-01 Metzger Michael A M-Exempt A Common Stock 15,000 7.20 108.0K 32,659
2020-11-23 Ordentlich Peter S-Sale D Common Stock 5,684 23.33 132.6K 24,288
2020-11-10 Morrison Briggs M-Exempt A Common Stock 17,466 7.20 125.8K 64,031
2020-11-09 Morrison Briggs M-Exempt A Common Stock 62,938 7.20 453.2K 109,503
2020-11-04 Metzger Michael A S-Sale D Common Stock 100,000 20.31 2.03M 17,659
2020-07-31 Meyers Michael L. Officer J-Other A Common Stock 2,665 7.97 21.2K 13,395
2020-07-13 Karydas Daphne D Employee Stock Option (right to buy) 215,000 18.95 4.07M 0
2020-07-06 Meyers Michael L. A-Award A Common Stock 3,500 0.00 10,730
2020-02-12 Shea Richard P A-Award A Stock Option (Right to Buy) 43,200 9.47 409.1K 43,200
2020-02-12 Podlesak Dennis A-Award A Stock Option (Right to Buy) 44,000 9.47 416.7K 44,000
2020-02-12 Ordentlich Peter A-Award A Stock Option (Right to Buy) 50,000 9.47 473.5K 50,000
2020-02-12 Morrison Briggs Director / Officer A-Award A Stock Option (Right to Buy) 194,000 9.47 1.84M 194,000
2020-02-12 Meyers Michael L. A-Award A Stock Option (Right to Buy) 50,825 9.47 481.3K 50,825
2020-02-12 Meury William A-Award A Stock Option (Right to Buy) 24,000 9.47 227.3K 24,000
2020-02-12 Metzger Michael A A-Award A Common Stock 15,000 0.00 17,659
2020-02-12 Legault Pierre A-Award A Stock Option (Right to Buy) 24,000 9.47 227.3K 24,000
2020-02-12 Katkin Keith A-Award A Stock Option (Right to Buy) 24,000 9.47 227.3K 24,000
2020-02-12 Jarrett Jennifer A-Award A Stock Option (Right to Buy) 24,000 9.47 227.3K 24,000
2020-02-12 Egros Fabrice Director A-Award A Stock Option (Right to Buy) 24,000 9.47 227.3K 24,000
2020-02-04 Morrison Briggs P-Purchase A Common Stock 12,500 8.00 100.0K 43,900
2020-01-31 Shea Richard P J-Other A Common Stock 1,505 7.97 12.0K 7,121
2019-10-10 Morrison Briggs Director / Officer P-Purchase A Common Stock 11,000 5.40 59.4K 31,400
2019-07-31 Shea Richard P J-Other A Common Stock 1,401 4.89 6.9K 5,616
2019-07-04 Metzger Michael A A-Award A Stock Option (Right to Buy) 200,000 9.15 1.83M 200,000
2019-06-10 Podlesak Dennis Director A-Award A Stock Option (Right to Buy) 44,000 7.88 346.7K 44,000
2019-06-10 Meury William A-Award A Stock Option (Right to Buy) 24,000 7.88 189.1K 24,000
2019-06-10 Legault Pierre A-Award A Stock Option (Right to Buy) 24,000 7.88 189.1K 24,000
2019-06-10 Katkin Keith Director A-Award A Stock Option (Right to Buy) 24,000 7.88 189.1K 24,000
2019-06-10 Jarrett Jennifer A-Award A Stock Option (Right to Buy) 24,000 7.88 189.1K 24,000

Executive team

Top executives
EBIT / Employee
-932.0K
Shares Outstanding
88.20M

Executive compensation

Executive compensation (annual)
# Year Executive Salary Bonus Stock award Option award Incentive Other Total % Stock-
based
Filing
1 2025 Michael A. Metzger Chief Executive Officer 754.3K 2.02M 3.45M 848.6K 10.0K 7.09M 77.25%
2 2025 Nick Botwood, M.B.B.S. Head of Research & Development, Chief Medical Officer 345.7K 285.8K 1.91M 334.1K 2.88M 76.39%
3 2025 Keith A. Goldan Chief Financial Officer 516.9K 569.6K 1.05M 325.6K 10.0K 2.47M 65.50%
4 2025 Luke J. Albrecht General Counsel and Secretary 496.9K 540.3K 949.0K 335.4K 10.0K 2.33M 63.87%
5 2025 Steve Closter Chief Commercial Officer 485.3K 496.4K 806.7K 327.6K 10.0K 2.13M 61.29%
6 2024 Michael A. Metzger Chief Executive Officer 715.0K 3.26M 3.21M 515.5K 10.0K 7.71M 83.90%
7 2024 Steve Closter Chief Commercial Officer 364.2K 745.3K 2.22M 214.8K 10.0K 3.56M 83.44%
8 2024 Neil Gallagher, M.D., Ph.D. President, Head of Research & Development 546.0K 1.07M 1.04M 269.6K 10.0K 2.93M 71.80%
9 2024 Keith A. Goldan Chief Financial Officer 497.0K 1.04M 1.05M 229.2K 10.0K 2.82M 73.93%
10 2024 Luke J. Albrecht General Counsel and Secretary 471.0K 868.9K 897.3K 222.5K 10.0K 2.47M 71.51%
11 2023 Michael A. Metzger Chief Executive Officer 678.4K 8.02M 417.2K 8.0K 9.13M 87.91%
12 2023 Neil Gallagher, M.D., Ph.D. President, Head of Research & Development 386.5K 3.32M 182.2K 5.3K 3.89M 85.25%
13 2023 Keith A. Goldan Chief Financial Officer 470.3K 2.15M 196.4K 8.0K 2.83M 76.13%
14 2023 Catherine Madigan, M.D. Chief Medical Officer 468.6K 2.15M 179.2K 8.0K 2.81M 76.64%
15 2023 Luke J. Albrecht General Counsel and Secretary 442.1K 1.96M 181.3K 8.0K 2.59M 75.62%
16 2022 Michael A. Metzger Chief Executive Officer 640.0K 3.06M 403.2K 8.0K 4.11M 74.44%
17 2022 Steve M. Sabus Chief Commercial Officer 38.0K 3.88M 3.92M 99.03%
18 2022 Keith A. Goldan Chief Financial Officer 249.9K 50.0K 2.50M 186.8K 8.0K 2.99M 85.14%
19 2022 Catherine Madigan, M.D. Chief Medical Officer 503.5K 1.98M 152.2K 8.0K 2.64M 74.90%
20 2022 Briggs W. Morrison, M.D. President, Head of Research and Development and Former Chief Executive Officer 637.5K 1.39M 334.7K 8.0K 2.37M 58.71%
21 2022 Luke J. Albrecht General Counsel and Secretary 421.0K 862.3K 176.8K 8.0K 1.47M 58.73%
22 2022 Alexander Nolte Vice President, Chief Accounting Officer and Former Interim Principal Financial Officer 338.0K 323.4K 91.5K 8.0K 760.9K 42.50%
23 2021 Briggs W. Morrison, M.D. Chief Executive Officer 618.6K 2.97M 309.3K 8.0K 3.90M 76.03%
24 2021 Briggs W. Morrison, M.D. President, Head of Research and Development and Former Chief Executive Officer 618.6K 2.97M 309.3K 8.0K 3.90M 76.03%
25 2021 Michael A. Metzger Chief Executive Officer 594.1K 2.43M 297.1K 8.0K 3.33M 73.03%
26 2021 Michael A. Metzger Chief Operating Officer 594.1K 2.43M 297.1K 8.0K 3.33M 73.03%
27 2021 Daphne Karydas Former Chief Financial Officer 307.7K 50.0K 1.78M 130.8K 8.0K 2.28M 78.21%
28 2021 Anjali Ganguli Chief Business Officer 308.6K 193.6K 1.43M 134.0K 8.0K 2.07M 78.23%
29 2020 Daphne Karydas Chief Financial Officer 200.9K 2.85M 80.8K 3.13M 91.00%
30 2020 Daphne Karydas Former Chief Financial Officer 200.9K 2.85M 80.8K 3.13M 91.00%
31 2020 Briggs W. Morrison, M.D. President, Head of Research and Development and Former Chief Executive Officer 600.5K 1.27M 285.3K 6.0K 2.17M 58.82%
32 2020 Briggs W. Morrison, M.D. Chief Executive Officer 600.5K 1.27M 285.3K 6.0K 2.17M 58.82%
33 2020 Michael A. Metzger Chief Operating Officer 576.8K 142.1K 950.7K 274.0K 6.0K 1.95M 56.05%
34 2020 Michael A. Metzger Chief Executive Officer 576.8K 142.1K 950.7K 274.0K 6.0K 1.95M 56.05%
35 2019 Michael A. Metzger Chief Operating Officer 540.3K 1.90M 252.0K 3.0K 2.70M 70.51%
36 2019 Briggs W. Morrison, M.D. Chief Executive Officer 583.1K 763.6K 262.4K 3.0K 1.61M 47.37%
37 2019 Michael L. Meyers, M.D., Ph.D. Chief Medical Officer 424.4K 219.2K 152.8K 22.2K 818.5K 26.78%
38 2018 Briggs W. Morrison, M.D. Chief Executive Officer 566.1K 1.26M 247.7K 3.0K 2.08M 60.74%
39 2018 Michael A. Metzger Chief Operating Officer 506.4K 790.5K 221.5K 3.0K 1.52M 51.96%
40 2018 Michael L. Meyers, M.D., Ph.D. Chief Medical Officer 412.0K 474.8K 144.2K 20.9K 1.05M 45.13%
41 2017 Briggs W. Morrison, M.D. Chief Executive Officer 549.6K 920.0K 204.5K 3.0K 1.68M 54.86%
42 2017 Michael A. Metzger Chief Operating Officer 491.6K 546.2K 182.9K 3.0K 1.22M 44.64%
43 2017 Michael L. Meyers, M.D., Ph.D. Chief Medical Officer 400.0K 379.8K 132.7K 21.0K 933.6K 40.69%
44 2016 Briggs W. Morrison, M.D. Chief Executive Officer 525.4K 100.0K 244.3K 3.0K 872.7K 0.00%
45 2016 Michael A. Metzger Chief Operating Officer 470.4K 40.0K 218.5K 3.0K 731.9K 0.00%
46 2016 Michael L. Meyers, M.D., Ph.D. Chief Medical Officer 378.8K 152.5K 19.6K 550.8K 0.00%
47 2015 Briggs W. Morrison, M.D. Chief Executive Officer 263.8K 109.6K 4.26M 100.2K 4.73M 89.99%
48 2015 Michael A. Metzger Chief Operating Officer 296.5K 50.0K 2.55M 120.0K 3.0K 3.02M 84.45%
49 2015 Michael L. Meyers, M.D., Ph.D. Chief Medical Officer 140.6K 1.21M 43.8K 4.5K 1.39M 86.46%
CEO compensation breakdown

Proxy statements

Proxy statements (DEF 14A)
Filing date Form type Filing
2026-04-30 DEFA14A
2026-04-30 DEF 14A
2025-04-01 DEFA14A
2025-04-01 DEF 14A
2024-04-02 DEFA14A
2024-04-02 DEF 14A

Recent SEC filings

Recent SEC filings
Filing date Form type Filing
2026-04-30 SC 13G
2026-04-30 DEFA14A
2026-04-30 DEF 14A
2026-04-30 ARS
2026-04-30 8-K
2026-04-30 10-Q
2026-03-27 SC 13G/A
2026-02-26 S-8
2026-02-26 8-K
2026-02-26 10-K

Executive team

NameTitleCompensationGender
Michael A. Metzger Chief Executive Officer & Director 1M male
Keith Alan Goldan CFO, Treasurer & Principal Accounting Officer 736.2K male
Luke J. Albrecht Senior Vice President, General Counsel & Secretary 703.5K male
Steven Closter Chief Commercial Officer 687.3K male
Richard A. Heyman Co-Founder
Ronald Evans Co-Founder, Advisor and Chair of Scientific Advisory Board
Sharon Klahre Vice President of Investor Relations & Communications
Michael Downes Co-Founder
Kevin McManus Chief People Officer male
Joseph Paul Eder Member of Scientific Advisory Board & Chief Medical Officer
Peter Ordentlich Co-Founder & Chief Scientific Officer
ESG Rating
B
BIOTECHNOLOGY
2026
E (Environmental)
59.2 / 56.3
Company / Sector avg.
S (Social)
68.6 / 62.4
Company / Sector avg.
G (Governance)
68.4 / 60.9
Company / Sector avg.
ESG Total
65.4 / 59.9
Company / Sector avg.
ESG Score History BIOTECHNOLOGY
Benchmark vs Sector
Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
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Dividend history

Earnings history

Earnings reports

Stock splits