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Septerna Inc (SEPN)

USD34.00 -0.54 (-1.56%)
US NASDAQ Healthcare Biotechnology
Address 250 East Grand Avenue 94080
South San Francisco, CA, US
CEO Jeffrey T. Finer
IPO 2024-10-25
CIK 1984086 ISIN US81734D1046

Explore sections of this company profile

Description

Septerna, Inc., a clinical-stage biotechnology company, discovers and develops G protein-coupled receptor (GPCR) oral small molecule products for the treatment of endocrinology, immunology and inflammation, and metabolic diseases. It develops PTH1R Program, oral small molecule Parathyroid Hormone 1 Receptor agonists for the treatment of hypoparathyroidism; SEP-631, an oral small molecule MRGPRX2 negative allosteric modulator (NAM) for chronic spontaneous urticaria and other mast cell diseases; and TSHR Program, an oral small molecule TSHR NAM for graves’ disease and thyroid eye disease. In addition, it focuses on other therapeutic areas, including neurology, women’s health, cardiovascular disease, and respiratory disease. It has global collaboration and license agreement with Novo Nordisk to discover, develop and commercialize multiple potential oral small molecule therapies for metabolic-related diseases based on certain specified molecular targets. The company was formerly known as GPCR NewCo, Inc. and changed its name to Septerna Inc. in June 2021. Septerna, Inc. was incorporated in 2019 and is headquartered in South San Francisco, California.

News Sentiment (7d)
68 Positive

Based on only 1 article — low confidence

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
USD34.00 -0.54 (-1.56%)
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Volume Profile
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Liquidity & share structure
Average Volume
378.0K
Beta
2.38
Float Shares
18.88M
Free Float %
41.9%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
+5.39% +0.28% +7.58% -3.57% +29.17% -10.90% +255.87% +16.07% +16.07% +16.07% +16.07%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
vs.
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Analyst Consensus (6 ratings, all time) Buy
Price Targets & DCF
Current price
34.00
Low 28.00 -17.6%
Consensus 39.00 +14.7%
Median 35.00 +2.9%
High 60.00 +76.5%
Ratings Trend (MoM) 100% Bullish
Rating 2026-05 Change
Strong Buy 1 0
Buy 8 0
Hold 0 0
Sell 0 0
Strong Sell 0 0
Price Target Summary
Period # Analysts Avg Target
Last Month
Last Quarter 1
60.00
+76.5%
Last Year 6
35.50
+4.4%
All Time 8
29.75
-12.5%
Quality scores
Altman Z-Score
3.23
Safe zone
Piotroski F-Score
3 / 9
Average
MOAT Score
1 / 10
No MOAT
Composite Rating
C
Overall Score
2 / 5
Medium
DCF Score
1 / 5
Low
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
3 / 5
Medium
P/E Score
1 / 5
Low
P/Book Score
3 / 5
Medium
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
    +4,174.5% Q1'26: +12,011.0% (vs Q1'25)
  • EPS growth Biotechnology: +29.7%
    +84.9% Q1'26: +61.2% (vs Q1'25)
  • FCF margin FCF growth · Biotechnology: +16.2%
    +180.7% Q1'26: -99.8% (vs Q1'25)
  • EBIT margin Biotechnology: +0.0%
    -175.8% Q1'26: +0.0% (vs Q1'25)
  • ROIC Biotechnology: -16.1%
    -558.7% Q1'26: +0.0% (vs Q1'25)
  • Share dilution Biotechnology: -3.4%
    +347.5% Q1'26: +1.9% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    -0.30× Q1'26: -0.43× (vs Q1'25)
Valuation Multiples From To
Price Forecast (3Y) From To
Model
Adjust
P/E
Theoretical Return — If Invested Today

* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.

DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (2.20) × ERP
WACC = 98% × Ke + 2% × Kd (4.1%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Current price: 34.00
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2024
actual
Dec 2025
actual
Dec 2026
7 Rev. Ana.
6 EPS Ana.
Dec 2027
7 Rev. Ana.
6 EPS Ana.
Dec 2028
6 Rev. Ana.
5 EPS Ana.
Dec 2029
5 Rev. Ana.
1 EPS Ana.
Dec 2030
3 Rev. Ana.
1 EPS Ana.
Revenue
1.08M
est: 719.0K (+49.5%)
45.95M
est: 38.37M (+19.8%)
65.68M
45.55M – 93.51M
+71.2% YoY
59.83M
36.62M – 77.53M
-8.9% YoY
63.76M
41.87M – 87.09M
+6.6% YoY
50.08M
32.88M – 68.40M
-21.5% YoY
86.16M
56.58M – 117.69M
+72.1% YoY
EBITDA
-79.42M
est: -359.5K (-21,992.4%)
-79.19M
est: -19.18M (-312.8%)
-32.84M
-46.76M – -22.77M
-71.2% YoY
-29.92M
-38.76M – -18.31M
+8.9% YoY
-31.88M
-43.55M – -20.93M
-6.6% YoY
-25.04M
-34.20M – -16.44M
+21.5% YoY
-43.08M
-58.84M – -28.29M
-72.1% YoY
EBIT
-80.82M
est: -359.5K (-22,382.1%)
-80.80M
est: -19.18M (-321.2%)
-32.84M
-46.76M – -22.77M
-71.2% YoY
-29.92M
-38.76M – -18.31M
+8.9% YoY
-31.88M
-43.55M – -20.93M
-6.6% YoY
-25.04M
-34.20M – -16.44M
+21.5% YoY
-43.08M
-58.84M – -28.29M
-72.1% YoY
Net Income
-71.80M
est: -375.82M (+80.9%)
-48.88M
est: -48.88M (+0.0%)
-89.44M
-161.16M – -29.14M
-83.0% YoY
-130.43M
-156.30M – -64.18M
-45.8% YoY
-115.16M
-155.33M – -74.99M
+11.7% YoY
-153.58M
-226.64M – -85.03M
-33.4% YoY
-167.65M
-247.41M – -92.82M
-9.2% YoY
SGA
16.56M
est: 14.64M (+13.2%)
29.16M
est: 781.06M (-96.3%)
1.34B
927.14M – 1.90B
+71.2% YoY
1.22B
745.39M – 1.58B
-8.9% YoY
1.30B
852.29M – 1.77B
+6.6% YoY
1.02B
669.36M – 1.39B
-21.5% YoY
1.75B
1.15B – 2.40B
+72.1% YoY
EPS
-7.26
est: -7.76 (+6.4%)
-1.10
est: -1.12 (+1.6%)
-1.87
-3.64 – -0.66
-66.9% YoY
-2.51
-3.53 – -1.45
-34.3% YoY
-2.61
-3.51 – -1.69
-4.1% YoY
-3.47
-5.12 – -1.92
-33.0% YoY
-3.79
-5.59 – -2.10
-9.2% YoY
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-12 C 2/5 1/5 1/5 1/5 3/5 1/5 3/5
2026-05-11 C 2/5 1/5 1/5 1/5 3/5 1/5 3/5
2026-05-08 C- 1/5 1/5 1/5 1/5 3/5 1/5 2/5
2026-05-07 C- 1/5 1/5 1/5 1/5 3/5 1/5 2/5
2026-05-06 C- 1/5 1/5 1/5 1/5 3/5 1/5 2/5
2026-05-05 C- 1/5 1/5 1/5 1/5 3/5 1/5 2/5
2026-05-04 C- 1/5 1/5 1/5 1/5 3/5 1/5 2/5
2026-05-01 C- 1/5 1/5 1/5 1/5 3/5 1/5 2/5
2026-04-30 C- 1/5 1/5 1/5 1/5 3/5 1/5 2/5
2026-04-29 C- 1/5 1/5 1/5 1/5 2/5 1/5 2/5
2026-04-28 C- 1/5 1/5 1/5 1/5 2/5 1/5 2/5
2026-04-27 C- 1/5 1/5 1/5 1/5 2/5 1/5 2/5
2026-04-24 C- 1/5 1/5 1/5 1/5 2/5 1/5 2/5
2026-04-23 C- 1/5 1/5 1/5 1/5 2/5 1/5 2/5
2026-04-22 C- 1/5 1/5 1/5 1/5 2/5 1/5 2/5
2026-04-21 C- 1/5 1/5 1/5 1/5 2/5 1/5 2/5
2026-04-20 C- 1/5 1/5 1/5 1/5 2/5 1/5 2/5
2026-04-17 C- 1/5 1/5 1/5 1/5 2/5 1/5 2/5
2026-04-16 C- 1/5 1/5 1/5 1/5 2/5 1/5 2/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
215.27M
OE per share TTM
4.72
Owner's Yield
19.36%
Maintenance CapEx ratio
Maint CapEx / Avg PPE
152.0%

Ownership Overview

Ownership breakdown
At a glance
Institutional holders
23
Total invested
7.20M
Insider transactions (90d)
0
Beneficial owners (>5%)
17
Beneficial owners (>5%)
# Reporting person Amount owned % of class Sole voting Shared voting Sole dispositive Shared dispositive Type Citizenship Filing date SEC filing
1 Peter Kolchinsky 7.00M 15.80% 7.00M 10.00 HC, IN United States 2024-11-04
2 RA Capital Management, L.P. 7.00M 15.80% 7.00M 10.00 IA, PN Delaware 2024-11-04
3 Rajeev Shah 7.00M 15.80% 7.00M 10.00 HC, IN United States 2024-11-04
4 RA Capital Healthcare Fund, L.P. 5.52M 12.40% 5.52M 10.00 PN Delaware 2024-11-04
5 Samsara BioCapital GP, LLC 2.77M 6.20% 2.77M OO Delaware 2024-11-04
6 Samsara BioCapital, L.P. 2.77M 6.20% 2.77M PN Delaware 2024-11-04
7 Srinivas Akkaraju 2.77M 6.20% 2.77M IN Delaware 2024-11-04
8 BVF Inc. 2.45M 5.50% 2.45M CO Delaware 2024-11-01
9 BVF Partners L.P. 2.45M 5.50% 2.45M IA, PN Delaware 2024-11-01
10 Mark N. Lampert 2.45M 5.50% 2.45M IN Delaware 2024-11-01
11 BVF GP Holdings LLC 2.30M 5.20% 2.30M OO Delaware 2024-11-01
12 BVF I GP LLC 1.30M 2.90% 1.30M OO Delaware 2024-11-01
13 Biotechnology Value Fund, L.P. 1.30M 2.90% 1.30M PN Delaware 2024-11-01
14 BVF II GP LLC 998.6K 2.20% 998.6K OO Delaware 2024-11-01
15 Biotechnology Value Fund II, L.P. 998.6K 2.20% 998.6K PN Delaware 2024-11-01
16 BVF Partners OS Ltd. 133.0K 1.00% 133.0K CO Delaware 2024-11-01
17 Biotechnology Value Trading Fund OS LP 133.0K 1.00% 133.0K PN Delaware 2024-11-01

Institutional Activity (13F)

Institutional ownership trend From To
13F snapshot — 2026 Q1
Investors holding
23
-104 vs prev Q
New positions
2
Closed positions
103
Increased
15
Reduced
3
Put/Call ratio
0.00
Calls held
Puts held
Top institutional holders
# Investor Shares / Δ Mkt value / Δ Own% / Δ Weight% / Δ Avg px / Perf. Hold / Status
1 194.5K +194.5K (+100.0%) 5.42B +5.4B (+100.0%) 0.44% +0.439 pp 5.36% +5.365 pp USD27.88 +0.0% 1 qtrs NEW
2 RA CAPITAL MANAGEMENT, L.P. 7.00M +— (+0.0%) 195.04M +63.5M (+48.2%) 15.78% -0.064 pp 2.00% +0.377 pp USD22.90 +21.7% 5 qtrs
3 TRV GP V, LLC 6.22M +— (+0.0%) 173.29M +56.4M (+48.2%) 14.02% -0.057 pp 40.38% +7.304 pp USD22.90 +21.7% 5 qtrs
4 DRIEHAUS CAPITAL MANAGEMENT LLC 4.81M -110.4K (-2.2%) 134.09M +41.5M (+44.9%) 10.85% -0.294 pp 0.91% +0.248 pp USD16.94 +64.6% 5 qtrs
5 TRV GP VI, LLC 4.21M +— (+0.0%) 117.42M +38.2M (+48.2%) 9.50% -0.038 pp 79.05% +6.789 pp USD18.60 +49.9% 5 qtrs
6 SAMSARA BIOCAPITAL, LLC 3.15M +— (+0.0%) 87.80M +28.6M (+48.2%) 7.10% -0.029 pp 9.06% +1.325 pp USD20.83 +33.8% 5 qtrs
7 GOLDMAN SACHS GROUP INC 2.72M +1.3M (+86.6%) 75.70M +48.3M (+176.6%) 6.12% +2.829 pp 0.01% +0.006 pp USD25.15 +10.9% 5 qtrs
8 SIREN, L.L.C. 2.00M -202.5K (-9.2%) 55.76M +14.3M (+34.6%) 4.51% -0.477 pp 1.66% +0.043 pp USD22.90 +21.7% 5 qtrs
9 BLACKROCK, INC. 1.80M +341.5K (+23.4%) 50.22M +22.8M (+82.9%) 4.06% +0.757 pp 0.00% +0.000 pp USD22.78 +22.4% 5 qtrs
10 BVF INC/IL 1.72M -2.3M (-57.1%) 47.98M -27.6M (-36.5%) 3.88% -5.212 pp 1.61% -1.447 pp USD15.33 +81.9% 5 qtrs
11 VANGUARD GROUP INC 1.51M -10.6K (-0.7%) 42.05M +13.5M (+47.2%) 3.40% -0.038 pp 0.00% +0.000 pp USD19.10 +46.0% 5 qtrs
12 AVORO CAPITAL ADVISORS LLC 1.34M +— (+0.0%) 37.29M +12.1M (+48.2%) 3.02% -0.012 pp 0.36% +0.033 pp USD19.90 +40.1% 5 qtrs
13 ADAR1 CAPITAL MANAGEMENT, LLC 1.16M -18.9K (-1.6%) 32.27M +10.1M (+45.8%) 2.61% -0.053 pp 2.37% +0.292 pp USD9.95 +180.2% 4 qtrs
14 FIRST LIGHT ASSET MANAGEMENT, LLC 620.8K +620.8K (+100.0%) 17.31M +17.3M (+100.0%) 1.40% +1.400 pp 1.32% +1.323 pp USD27.88 +0.0% 1 qtrs NEW
15 VR ADVISER, LLC 610.8K +— (+0.0%) 17.03M +5.5M (+48.2%) 1.38% -0.006 pp 0.84% +0.195 pp USD11.52 +142.0% 3 qtrs
16 GEODE CAPITAL MANAGEMENT, LLC 572.7K +27.0K (+5.0%) 15.97M +5.7M (+55.6%) 1.29% +0.056 pp 0.00% +0.000 pp USD20.17 +38.2% 5 qtrs
17 CASDIN CAPITAL, LLC 553.3K +— (+0.0%) 15.43M +5.0M (+48.2%) 1.25% -0.005 pp 0.96% +0.090 pp USD22.90 +21.7% 5 qtrs
18 PRIMECAP MANAGEMENT CO/CA/ 546.1K +546.1K (+100.0%) 15.23M +15.2M (+100.0%) 1.23% +1.232 pp 0.01% +0.012 pp USD27.88 +0.0% 1 qtrs NEW
19 STATE STREET CORP 540.0K +121.1K (+28.9%) 15.06M +7.2M (+91.1%) 1.22% +0.269 pp 0.00% +0.000 pp USD20.79 +34.1% 5 qtrs
20 PERCEPTIVE ADVISORS LLC 433.2K -108.3K (-20.0%) 12.08M +1.9M (+18.6%) 0.98% -0.249 pp 0.22% -0.079 pp USD10.57 +163.8% 5 qtrs
21 WOODLINE PARTNERS LP 385.3K +102.7K (+36.4%) 10.74M +5.4M (+102.1%) 0.87% +0.229 pp 0.04% +0.017 pp USD18.14 +53.7% 5 qtrs
22 SOLEUS CAPITAL MANAGEMENT, L.P. 383.4K +365.1K (+1,999.5%) 10.69M +10.3M (+3,011.8%) 0.86% +0.823 pp 0.39% +0.377 pp USD27.56 +1.2% 5 qtrs
23 CATALIO CAPITAL MANAGEMENT, LP 294.4K +— (+0.0%) 8.21M +2.7M (+48.2%) 0.66% -0.003 pp 1.45% +0.427 pp USD22.90 +21.7% 5 qtrs
24 MARSHALL WACE, LLP 226.9K +226.9K (+100.0%) 6.33M +6.3M (+100.0%) 0.51% +0.512 pp 0.01% +0.006 pp USD27.88 +0.0% 1 qtrs NEW
25 UNIVERSAL- BETEILIGUNGS- UND SERVICEGESELLSCHAFT MBH 222.7K +— (+0.0%) 6.21M +2.0M (+48.2%) 0.50% -0.002 pp 0.01% +0.003 pp USD16.26 +71.5% 5 qtrs
26 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 187.2K +337.0 (+0.2%) 5.22M +1.7M (+48.5%) 0.42% -0.001 pp 0.00% +0.000 pp USD19.81 +40.7% 5 qtrs
27 INVESCO LTD. 162.0K -15.1K (-8.5%) 4.52M +1.2M (+35.6%) 0.37% -0.036 pp 0.00% +0.000 pp USD19.08 +46.1% 5 qtrs
28 NORTHERN TRUST CORP 154.2K -13.1K (-7.9%) 4.30M +1.2M (+36.6%) 0.35% -0.031 pp 0.00% +0.000 pp USD21.56 +29.3% 5 qtrs
29 MILLENNIUM MANAGEMENT LLC 107.5K -276.7K (-72.0%) 3.00M -4.2M (-58.5%) 0.24% -0.628 pp 0.00% -0.002 pp USD17.05 +63.5% 4 qtrs
30 MORGAN STANLEY 104.0K +49.5K (+90.9%) 2.90M +1.9M (+183.0%) 0.23% +0.111 pp 0.00% +0.000 pp USD20.44 +36.4% 5 qtrs
31 TWO SIGMA INVESTMENTS, LP 92.8K +475.0 (+0.5%) 2.59M +850.7K (+49.0%) 0.21% +0.000 pp 0.00% +0.001 pp USD8.11 +243.8% 4 qtrs
32 JANE STREET GROUP, LLC 80.2K -272.2K (-77.2%) 2.24M -4.4M (-66.3%) 0.18% -0.617 pp 0.00% -0.001 pp USD10.10 +176.0% 4 qtrs
33 FEDERATED HERMES, INC. 78.9K +78.9K (+100.0%) 2.20M +2.2M (+100.0%) 0.18% +0.178 pp 0.00% +0.004 pp USD27.88 +0.0% 1 qtrs NEW
34 HIGHVISTA STRATEGIES LLC 78.7K +78.7K (+100.0%) 2.19M +2.2M (+100.0%) 0.18% +0.177 pp 0.56% +0.565 pp USD27.88 +0.0% 1 qtrs NEW
35 CITADEL ADVISORS LLC 75.9K +75.9K (+100.0%) 2.12M +2.1M (+100.0%) 0.17% +0.171 pp 0.00% +0.000 pp USD27.88 +0.0% 5 qtrs
36 SUSQUEHANNA INTERNATIONAL GROUP, LLP 69.2K -3.4K (-4.7%) 1.93M +563.7K (+41.3%) 0.16% -0.008 pp 0.00% +0.000 pp USD14.47 +92.7% 4 qtrs
37 UBS GROUP AG 68.8K +9.8K (+16.5%) 1.92M +808.0K (+72.7%) 0.16% +0.022 pp 0.00% +0.000 pp USD15.56 +79.2% 5 qtrs
38 JPMORGAN CHASE & CO 68.3K +59.6K (+682.3%) 1.91M +1.7M (+1,059.5%) 0.15% +0.134 pp 0.00% +0.000 pp USD27.04 +3.1% 5 qtrs
39 RANGELEY CAPITAL, LLC 65.8K -22.2K (-25.2%) 1.83M +179.2K (+10.8%) 0.15% -0.051 pp 1.52% +0.091 pp USD10.45 +166.8% 4 qtrs
40 JACOBS LEVY EQUITY MANAGEMENT, INC 61.4K +25.6K (+71.5%) 1.71M +1.0M (+154.2%) 0.14% +0.057 pp 0.01% +0.004 pp USD22.59 +23.4% 2 qtrs
41 BANK OF NEW YORK MELLON CORP 55.3K +3.7K (+7.2%) 1.54M +571.5K (+58.8%) 0.12% +0.008 pp 0.00% +0.000 pp USD20.66 +34.9% 5 qtrs
42 AMERICAN CENTURY COMPANIES INC 50.7K +25.4K (+100.5%) 1.41M +937.6K (+197.2%) 0.11% +0.057 pp 0.00% +0.001 pp USD23.36 +19.3% 2 qtrs
43 LONGAEVA PARTNERS L.P. 49.9K -7.2K (-12.6%) 1.39M +317.9K (+29.6%) 0.11% -0.017 pp 0.12% -0.038 pp USD18.81 +48.2% 2 qtrs
44 NUMERAI GP LLC 45.9K +45.9K (+100.0%) 1.28M +1.3M (+100.0%) 0.10% +0.103 pp 0.15% +0.154 pp USD27.88 +0.0% 1 qtrs NEW
45 TREXQUANT INVESTMENT LP 44.0K +44.0K (+100.0%) 1.23M +1.2M (+100.0%) 0.10% +0.099 pp 0.01% +0.011 pp USD27.88 +0.0% 1 qtrs NEW
46 BARCLAYS PLC 38.1K +8.0K (+26.7%) 1.06M +497.3K (+87.8%) 0.09% +0.018 pp 0.00% +0.000 pp USD20.42 +36.5% 5 qtrs
47 EXODUSPOINT CAPITAL MANAGEMENT, LP 37.9K +37.9K (+100.0%) 1.06M +1.1M (+100.0%) 0.09% +0.085 pp 0.01% +0.008 pp USD27.88 +0.0% 1 qtrs NEW
48 BANK OF AMERICA CORP /DE/ 37.6K -13.9K (-27.0%) 1.05M +79.5K (+8.2%) 0.08% -0.032 pp 0.00% +0.000 pp USD12.01 +132.1% 5 qtrs
49 ALYESKA INVESTMENT GROUP, L.P. 35.0K +— (+0.0%) 975.8K +317.5K (+48.2%) 0.08% 0.000 pp 0.00% +0.001 pp USD22.90 +21.7% 5 qtrs
50 ALGERT GLOBAL LLC 34.9K +34.9K (+100.0%) 974.0K +974.0K (+100.0%) 0.08% +0.079 pp 0.02% +0.015 pp USD27.88 +0.0% 1 qtrs NEW
51 ACADIAN ASSET MANAGEMENT LLC 30.9K +30.9K (+100.0%) 858.0K +858.0K (+100.0%) 0.07% +0.070 pp 0.00% +0.001 pp USD27.88 +0.0% 1 qtrs NEW
52 WELLS FARGO & COMPANY/MN 26.5K +6.4K (+31.7%) 739.6K +360.7K (+95.2%) 0.06% +0.014 pp 0.00% +0.000 pp USD21.33 +30.7% 5 qtrs
53 RHUMBLINE ADVISERS 26.4K -1.2K (-4.3%) 736.6K +217.3K (+41.9%) 0.06% -0.003 pp 0.00% +0.000 pp USD18.64 +49.6% 5 qtrs
54 NUVEEN, LLC 25.8K +1.8K (+7.7%) 719.2K +268.5K (+59.6%) 0.06% +0.004 pp 0.00% +0.000 pp USD9.97 +179.6% 4 qtrs
55 TWO SIGMA ADVISERS, LP 25.7K +5.0K (+24.2%) 716.5K +327.1K (+84.0%) 0.06% +0.011 pp 0.00% +0.001 pp USD20.57 +35.5% 2 qtrs
56 PRICE T ROWE ASSOCIATES INC /MD/ 25.4K -2.0K (-7.2%) 710.0K +194.0K (+37.6%) 0.06% -0.005 pp 0.00% +0.000 pp USD21.65 +28.8% 5 qtrs
57 LOGOS GLOBAL MANAGEMENT LP 23.5K -60.0K (-71.8%) 656.5K -915.0K (-58.2%) 0.05% -0.136 pp 0.04% -0.101 pp USD22.90 +21.7% 5 qtrs
58 XTX TOPCO LTD 23.3K +23.3K (+100.0%) 650.0K +650.0K (+100.0%) 0.05% +0.053 pp 0.02% +0.017 pp USD27.88 +0.0% 4 qtrs
59 ALLIANCEBERNSTEIN L.P. 19.6K -2.5K (-11.3%) 546.4K +130.7K (+31.5%) 0.04% -0.006 pp 0.00% +0.000 pp USD10.57 +163.8% 3 qtrs
60 TUDOR INVESTMENT CORP ET AL 18.1K +18.1K (+100.0%) 503.3K +503.3K (+100.0%) 0.04% +0.041 pp 0.00% +0.001 pp USD27.88 +0.0% 3 qtrs
61 FRANKLIN RESOURCES INC 16.9K +16.9K (+100.0%) 469.8K +469.8K (+100.0%) 0.04% +0.038 pp 0.00% +0.000 pp USD27.88 +0.0% 1 qtrs NEW
62 RUSSELL INVESTMENTS GROUP, LTD. 15.3K +13.4K (+707.5%) 426.8K +391.2K (+1,096.9%) 0.03% +0.030 pp 0.00% +0.000 pp USD26.76 +4.2% 2 qtrs
63 DEUTSCHE BANK AG\ 14.9K +744.0 (+5.3%) 414.8K +148.9K (+56.0%) 0.03% +0.002 pp 0.00% +0.000 pp USD17.75 +57.1% 5 qtrs
64 SQUAREPOINT OPS LLC 14.8K +14.8K (+100.0%) 413.9K +413.9K (+100.0%) 0.03% +0.034 pp 0.00% +0.000 pp USD27.88 +0.0% 3 qtrs
65 STRS OHIO 14.6K +14.6K (+100.0%) 407.0K +407.0K (+100.0%) 0.03% +0.033 pp 0.00% +0.002 pp USD27.88 +0.0% 5 qtrs
66 LOS ANGELES CAPITAL MANAGEMENT LLC 18.6K +18.6K (+100.0%) 398.6K +398.6K (+100.0%) 0.04% +0.042 pp 0.00% +0.001 pp USD27.88 +0.0% 1 qtrs NEW
67 AMERIPRISE FINANCIAL INC 14.1K +14.1K (+100.0%) 392.8K +392.8K (+100.0%) 0.03% +0.032 pp 0.00% +0.000 pp USD27.88 +0.0% 1 qtrs NEW
68 METLIFE INVESTMENT MANAGEMENT, LLC 13.7K +— (+0.0%) 381.5K +124.1K (+48.2%) 0.03% 0.000 pp 0.00% +0.001 pp USD10.57 +163.8% 5 qtrs
69 INTECH INVESTMENT MANAGEMENT LLC 13.3K +13.3K (+100.0%) 370.3K +370.3K (+100.0%) 0.03% +0.030 pp 0.00% +0.003 pp USD27.88 +0.0% 3 qtrs
70 ADVISOR GROUP HOLDINGS, INC. 12.7K -170.0 (-1.3%) 353.9K +111.9K (+46.3%) 0.03% -0.001 pp 0.00% +0.000 pp USD18.67 +49.3% 3 qtrs
71 DYNAMIC TECHNOLOGY LAB PRIVATE LTD 10.8K +10.8K (+100.0%) 301.0K +301.0K (+100.0%) 0.02% +0.024 pp 0.07% +0.068 pp USD27.88 +0.0% 1 qtrs NEW
72 PHARVISION ADVISERS, LLC 10.7K -1.2K (-10.0%) 299.4K +75.0K (+33.4%) 0.02% -0.003 pp 0.15% +0.025 pp USD11.80 +136.3% 3 qtrs
73 PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO 10.6K +10.6K (+100.0%) 295.4K +295.4K (+100.0%) 0.02% +0.024 pp 0.00% +0.001 pp USD27.88 +0.0% 1 qtrs NEW
74 VIRTUS INVESTMENT ADVISERS, INC. 10.5K +10.5K (+100.0%) 291.5K +291.5K (+100.0%) 0.02% +0.024 pp 0.08% +0.079 pp USD27.88 +0.0% 1 qtrs NEW
75 CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD. 10.3K +10.3K (+100.0%) 287.1K +287.1K (+100.0%) 0.02% +0.023 pp 0.02% +0.022 pp USD27.88 +0.0% 1 qtrs NEW
76 BAADER BANK AKTIENGESELLSCHAFT 10.0K +10.0K (+100.0%) 278.8K +278.8K (+100.0%) 0.02% +0.023 pp 0.02% +0.019 pp USD27.88 +0.0% 1 qtrs NEW
77 MIRAE ASSET GLOBAL ETFS HOLDINGS LTD. 9.9K +143.0 (+1.5%) 277.0K +92.8K (+50.4%) 0.02% +0.000 pp 0.00% +0.000 pp USD21.56 +29.3% 5 qtrs
78 ATOM INVESTORS LP 9.8K +9.8K (+100.0%) 273.0K +273.0K (+100.0%) 0.02% +0.022 pp 0.02% +0.022 pp USD27.88 +0.0% 1 qtrs NEW
79 CITIGROUP INC 9.6K +9.3K (+3,739.8%) 266.6K +261.9K (+5,590.9%) 0.02% +0.021 pp 0.00% +0.000 pp USD27.48 +1.5% 5 qtrs
80 GRAHAM CAPITAL MANAGEMENT, L.P. 9.0K +9.0K (+100.0%) 250.1K +250.1K (+100.0%) 0.02% +0.020 pp 0.01% +0.006 pp USD27.88 +0.0% 1 qtrs NEW
81 JUMP FINANCIAL, LLC 8.4K +8.4K (+100.0%) 234.2K +234.2K (+100.0%) 0.02% +0.019 pp 0.00% +0.003 pp USD27.88 +0.0% 1 qtrs NEW
82 BANK OF NOVA SCOTIA 8.3K +8.3K (+100.0%) 231.4K +231.4K (+100.0%) 0.02% +0.019 pp 0.00% +0.000 pp USD27.88 +0.0% 1 qtrs NEW
83 AQR CAPITAL MANAGEMENT LLC 7.8K +7.8K (+100.0%) 218.2K +218.2K (+100.0%) 0.02% +0.018 pp 0.00% +0.000 pp USD27.88 +0.0% 1 qtrs NEW
84 NEW YORK STATE COMMON RETIREMENT FUND 5.6K +2.7K (+93.1%) 156.1K +101.6K (+186.2%) 0.01% +0.006 pp 0.00% +0.000 pp USD20.72 +34.6% 5 qtrs
85 BNP PARIBAS ARBITRAGE, SNC 5.4K +1.3K (+31.1%) 151.9K +73.8K (+94.4%) 0.01% +0.003 pp 0.00% +0.000 pp USD20.22 +37.9% 5 qtrs
86 POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY 5.2K +— (+0.0%) 144.3K +46.9K (+48.2%) 0.01% +0.000 pp 0.00% +0.000 pp USD9.87 +182.5% 4 qtrs
87 BALYASNY ASSET MANAGEMENT L.P. 3.6K +3.6K (+100.0%) 99.6K +99.6K (+100.0%) 0.01% +0.008 pp 0.00% +0.000 pp USD27.88 +0.0% 1 qtrs NEW
88 FMR LLC 3.3K -131.0 (-3.8%) 92.2K +27.5K (+42.6%) 0.01% 0.000 pp 0.00% +0.000 pp USD21.77 +28.1% 5 qtrs
89 CAITONG INTERNATIONAL ASSET MANAGEMENT CO., LTD 3.2K +3.2K (+100.0%) 88.4K +88.4K (+100.0%) 0.01% +0.007 pp 0.02% +0.022 pp USD27.88 +0.0% 3 qtrs
90 MIRAE ASSET GLOBAL INVESTMENTS CO., LTD. 2.2K +2.2K (+100.0%) 60.7K +60.7K (+100.0%) 0.00% +0.005 pp 0.00% +0.000 pp USD27.88 +0.0% 1 qtrs NEW
91 TOWER RESEARCH CAPITAL LLC (TRC) 2.2K +1.2K (+124.8%) 60.1K +42.1K (+233.2%) 0.00% +0.003 pp 0.00% +0.001 pp USD22.21 +25.5% 5 qtrs
92 AMERITAS INVESTMENT PARTNERS, INC. 1.9K +— (+0.0%) 54.2K +17.6K (+48.2%) 0.00% +0.000 pp 0.00% +0.001 pp USD22.90 +21.7% 5 qtrs
93 LEGAL & GENERAL GROUP PLC 1.9K +— (+0.0%) 54.2K +17.6K (+48.1%) 0.00% +0.000 pp 0.00% +0.000 pp USD22.23 +25.4% 5 qtrs
94 COVESTOR LTD 1.9K -1.7K (-46.4%) 54.0K -14.0K (-20.6%) 0.00% -0.004 pp 0.03% -0.009 pp USD13.52 +106.2% 3 qtrs
95 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 1.3K -55.0 (-4.0%) 36.7K +10.9K (+42.3%) 0.00% 0.000 pp 0.00% +0.000 pp USD6.33 +340.4% 5 qtrs
Ownership breakdown by holder

ETF Ownership

Top ETFs holding this stock Held by 93 ETFs in our universe
# ETF Weight Est. AUM exposure TER
1 State Street SPDR S&P Pharmaceuticals ETF XPH 1.06% 5.01M 0.35%
2 Virtus Biotech Clinical Trials ETF BBC 0.62% 354.1K 0.65%
3 First Trust Multi-Manager Small Cap Opportunities ETF MMSC 0.52% 277.2K 0.95%
4 American Century Small Cap Growth Insights ETF ACSG 0.23% 57.3K 0.49%
5 Direxion Daily Pharmaceutical & Medical Bull 3X ETF PILL 0.22% 51.5K 1.22%
6 Royce Quant Small-Cap Quality Value ETF SQLV 0.19% 55.6K 0.60%
7 iShares U.S. Pharmaceuticals ETF IHE 0.19% 2.48M 0.38%
8 Federated Hermes MDT Small Cap Core ETF FSCC 0.15% 246.3K 0.51%
9 JPMorgan Diversified Return U.S. Small Cap Equity ETF JPSE 0.11% 670.9K 0.29%
10 Invesco NASDAQ Biotech UCITS ETF SBIO.L 0.11% 515.7K 0.40%

Insider Activity

Insider Activity — Latest Quarter
Ratio by transactions
0.25
Bearish
Ratio by volume
0.50
Neutral
Buys
1
Sells
4
Shares acquired
4.0K
Shares disposed
8.0K
Cash buys
Cash sales
3.00
Net activity
-4,000
Insider buys vs sells (history) From To
Recent insider transactions From To
Date Person Role Transaction A/D Security Shares Price Value Owned after D/I Filing
2026-04-15 Bhatt Elizabeth Officer M-Exempt A Common Stock 4,000 6.81 27.2K 178,209 D
2026-03-02 Shaikhly Samira Officer M-Exempt A Common Stock 53,714 1.55 83.3K 54,507 D
2026-02-18 Bhatt Elizabeth Officer M-Exempt A Common Stock 4,000 6.81 27.2K 178,209 D
2026-02-06 Wilson Mark Andrew Officer A-Award A Stock Option (Right to Buy) 165,000 25.41 4.19M 165,000 D
2026-02-06 Shaikhly Samira Officer A-Award A Stock Option (Right to Buy) 80,000 25.41 2.03M 80,000 D
2026-02-06 Long Daniel D. Officer A-Award A Stock Option (Right to Buy) 80,000 25.41 2.03M 80,000 D
2026-02-06 Labrucherie Gil M Officer A-Award A Stock Option (Right to Buy) 125,000 25.41 3.18M 125,000 D
2026-02-06 Klein Uwe Officer A-Award A Stock Option (Right to Buy) 80,000 25.41 2.03M 80,000 D
2026-02-06 Kim Jae B. Officer A-Award A Stock Option (Right to Buy) 125,000 25.41 3.18M 125,000 D
2026-02-06 Finer Jeffrey Director / Officer A-Award A Stock Option (Right to Buy) 400,000 25.41 10.16M 400,000 D
2026-02-06 Bhatt Elizabeth Officer A-Award A Stock Option (Right to Buy) 155,000 25.41 3.94M 155,000 D
2026-01-05 Wilson Mark Andrew 0 0.00 0
2025-11-10 Long Daniel D. Officer S-Sale D Common Stock 3,501 18.06 63.2K 92,911 D
2025-09-25 Gottesdiener Keith Michael 0 0.00 0
2025-08-18 Klein Uwe Officer M-Exempt D Stock Option (Right to Buy) 7,621 6.81 51.9K 33,027 D
2025-08-07 Shaikhly Samira Officer A-Award A Stock Option (Right to Buy) 30,000 11.70 351.0K 30,000 D
2025-08-07 Long Daniel D. Officer A-Award A Stock Option (Right to Buy) 30,000 11.70 351.0K 30,000 D
2025-08-07 Labrucherie Gil M Officer A-Award A Stock Option (Right to Buy) 37,500 11.70 438.8K 37,500 D
2025-08-07 Klein Uwe Officer A-Award A Stock Option (Right to Buy) 30,000 11.70 351.0K 30,000 D
2025-08-07 Kim Jae B. Officer A-Award A Stock Option (Right to Buy) 55,000 11.70 643.5K 55,000 D
2025-08-07 Finer Jeffrey Director / Officer A-Award A Stock Option (Right to Buy) 210,000 11.70 2.46M 210,000 D
2025-08-07 Bhatt Elizabeth Officer A-Award A Stock Option (Right to Buy) 95,000 11.70 1.11M 95,000 D
2025-06-17 Tong Jeffrey K Director A-Award A Stock Option (Right to Buy) 16,623 10.24 170.2K 16,623 D
2025-06-17 Simson Jake Director A-Award A Stock Option (Right to Buy) 16,623 10.24 170.2K 16,623 D
2025-06-17 Sharp Shalini Director A-Award A Stock Option (Right to Buy) 16,623 10.24 170.2K 16,623 D
2025-06-17 RA CAPITAL MANAGEMENT, L.P. Director / 10% Owner A-Award A Stock Option (Right to Buy) 16,623 10.24 170.2K 16,623 I
2025-06-17 Ezekowitz Alan Director A-Award A Stock Option (Right to Buy) 16,623 10.24 170.2K 16,623 D
2025-06-17 Coulie Bernard Director A-Award A Stock Option (Right to Buy) 16,623 10.24 170.2K 16,623 D
2025-06-17 Bassan Abraham Director A-Award A Stock Option (Right to Buy) 16,623 10.24 170.2K 16,623 D
2025-04-03 Finer Jeffrey Director / Officer M-Exempt A Common Stock 5,000 2.76 13.8K 826,907 D
2025-04-02 Finer Jeffrey Director / Officer M-Exempt A Common Stock 50,000 2.76 138.0K 821,907 D

Executive team

Top executives
EBIT / Employee
-621.5K
Shares Outstanding
45.08M

Executive compensation

Executive compensation (annual)
# Year Executive Salary Bonus Stock award Option award Incentive Other Total % Stock-
based
Filing
1 2025 Gil M. Labrucherie, CFA, J.D. Chief Financial Officer 479.5K 223.1K 2.54M 2.4K 3.24M 78.24%
2 2025 Jeffrey Finer, M.D., Ph.D Chief Executive Officer 635.0K 401.6K 1.89M 5.0K 2.93M 64.49%
3 2025 Liz Bhatt, M.S., M.B.A President and Chief Operating Officer 500.0K 230.0K 855.8K 5.0K 1.59M 53.80%
4 2024 Jeffrey Finer, M.D., Ph.D. Chief Executive Officer 550.2K 365.9K 3.80M 3.0K 4.72M 80.53%
5 2024 Jeffrey Finer, M.D., Ph.D Chief Executive Officer 550.2K 365.9K 3.80M 3.0K 4.72M 80.53%
6 2024 Jae B. Kim, M.D. Chief Medical Officer 125.1K 108.1K 1.63M 3.0K 1.87M 87.37%
7 2024 Liz Bhatt, M.S., M.B.A. Chief Operating Officer 449.6K 209.3K 956.8K 3.0K 1.62M 59.11%
8 2024 Liz Bhatt, M.S., M.B.A President and Chief Operating Officer 449.6K 209.3K 956.8K 3.0K 1.62M 59.11%
9 2023 Jeffrey Finer, M.D., Ph.D. Chief Executive Officer 501.4K 284.3K 1.35M 3.0K 2.14M 63.08%
10 2023 Liz Bhatt, M.S., M.B.A. Chief Operating Officer 413.3K 203.3K 264.2K 3.0K 883.7K 29.89%
CEO compensation breakdown

Proxy statements

Proxy statements (DEF 14A)
Filing date Form type Filing
2026-04-30 DEFA14A
2026-04-30 DEF 14A
2025-04-29 DEFA14A
2025-04-29 DEF 14A

Recent SEC filings

Recent SEC filings
Filing date Form type Filing
2026-05-11 8-K
2026-05-11 10-Q
2026-04-30 DEFA14A
2026-04-30 DEF 14A
2026-04-30 ARS
2026-04-17 4
2026-04-13 8-K
2026-03-10 S-3ASR
2026-03-09 S-8
2026-03-09 8-K

Executive team

NameTitleCompensationGender
Jeffrey T. Finer Co-Founder, Chief Executive Officer & Director 1M
Elizabeth Bhatt President & Chief Operating Officer 735.0K female
Gilbert Labrucherie Chief Financial Officer 711.7K male
Samira Shaikhly Chief People Officer 536.5K female
Jae Kim FACC Chief Medical Officer 486.3K
George Xu Senior Director of Corporate Development & Portfolio Strategy male
Mark A. Wilson Chief Legal Officer male
Patrick Sexton Co-Founder and Member of Cross-Functional Scientific & Drug Discovery Advisory Board
Richard Hansen Vice President of Technology male
Robert J. Lefkowitz Co-Founder and Member of Cross-Functional Scientific & Drug Discovery Advisory Board
Arthur Christopoulos BPHARM Co-Founder and Member of Cross-Functional Scientific & Drug Discovery Advisory Board
ESG Rating
B
BIOTECHNOLOGY
Rank: 207 out of 662
2026
E (Environmental)
60.5 / 56.3
Company / Sector avg.
S (Social)
63.5 / 62.4
Company / Sector avg.
G (Governance)
59.1 / 60.9
Company / Sector avg.
ESG Total
61.0 / 59.9
Company / Sector avg.
ESG Score History BIOTECHNOLOGY
Benchmark vs Sector
Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend history

Earnings history

Earnings reports

Stock splits