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Santhera Pharmaceuticals Holding AG (SANN.SW)

CHF15.82 -0.08 (-0.50%)
CH SIX Healthcare Biotechnology
Address Hohenrainstrasse 24 4133
Pratteln, BL, CH
CEO Dario Eklund
IPO 2006-11-03
ISIN CH1276028821

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Also trades on London Stock Exchange · 0QN1.L (CHF) Other OTC · SPHDF (USD) Swiss Exchange · SANN.SW (CHF)
Description

Santhera Pharmaceuticals Holding AG, a specialty pharmaceutical company, together with its subsidiaries, develops and sells medicines for rare neuromuscular and pulmonary diseases with high unmet medical need in the Europe, North America, and Asia. The company’s lead pipeline candidate includes Vamorolone, which is developed for the treatments of Duchenne muscular dystrophy. Its clinical stage pipeline also comprises Lonodelestat for the treatment of cystic fibrosis and other neutrophilic pulmonary diseases. Santhera Pharmaceuticals Holding AG was founded in 2004 and is based in Pratteln, Switzerland.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
CHF15.82 -0.08 (-0.50%)
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Volume Profile
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Liquidity & share structure
Average Volume
88.9K
Beta
-0.31
Float Shares
11.28M
Free Float %
77.7%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
+2.13% -0.37% -4.12% -3.55% +33.61% +34.27% +23.86% +91.54% -20.10% -97.82% -98.20%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
vs.
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Price Targets & DCF
Current price
15.82
Ratings Trend (MoM) 100% Bullish
Rating 2026-05 Change
Strong Buy 0 0
Buy 1 0
Hold 0 0
Sell 0 0
Strong Sell 0 0
Quality scores
Altman Z-Score
-5.79
Distress
Piotroski F-Score
2 / 9
Weak
MOAT Score
0 / 10
No MOAT
Composite Rating
C
Overall Score
2 / 5
Medium
DCF Score
1 / 5
Low
ROE Score
5 / 5
High
ROA Score
1 / 5
Low
D/E Score
1 / 5
Low
P/E Score
1 / 5
Low
P/Book Score
1 / 5
Low
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
    +97.3% Q4'25: -46.5% (vs Q4'23)
  • EPS growth Biotechnology: +29.7%
    -2.4% Q4'25: -111.1% (vs Q4'23)
  • FCF margin FCF growth · Biotechnology: +16.2%
    -60.3% Q4'25: -26.7% (vs Q4'23)
  • EBIT margin Biotechnology: +0.0%
    -49.0% Q4'25: -4.5% (vs Q4'23)
  • ROIC Biotechnology: -16.1%
    -59.5% Q4'25: -14.9% (vs Q4'23)
  • Share dilution Biotechnology: -3.4%
    +14.4% Q4'25: +20.0% (vs Q4'23)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    -3.04× Q4'25: 50.92× (vs Q4'23)
Valuation Multiples From To
Price Forecast (3Y) From To
Model
Adjust
P/E
Theoretical Return — If Invested Today

* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.

DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (-0.34) × ERP
WACC = 68% × Ke + 32% × Kd (11.8%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Current price: 15.82
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2015
actual
Dec 2016
actual
Dec 2017
actual
Dec 2018
actual
Dec 2019
actual
Dec 2020
actual
Dec 2021
actual
Dec 2022
actual
Dec 2023
actual
Dec 2024
actual
Dec 2025
actual
Dec 2026
1 Rev. Ana.
1 EPS Ana.
Dec 2027
1 Rev. Ana.
1 EPS Ana.
Dec 2028
1 Rev. Ana.
1 EPS Ana.
Revenue
4.32M
est: 5.65M (-23.5%)
19.03M
est: 19.00M (+0.2%)
22.94M
est: 22.90M (+0.2%)
31.66M
est: 32.00M (-1.1%)
75.38M
est: 77.00M (-2.1%)
15.01M
est: 15.00M (+0.1%)
-1.60M
est: 5.35M (-129.8%)
7.47M
est: 5.16M (+44.8%)
103.41M
est: 113.59M (-9.0%)
39.12M
est: 31.95M (+22.4%)
77.19M
est: 77.36M (-0.2%)
96.35M
96.35M – 96.35M
+24.5% YoY
119.55M
119.55M – 119.55M
+24.1% YoY
140.50M
140.50M – 140.50M
+17.5% YoY
EBITDA
4.06M
est: -723.8K (+660.3%)
-29.92M
est: -2.43M (-1,129.2%)
-44.05M
est: -2.93M (-1,401.5%)
-45.62M
est: -4.10M (-1,012.8%)
-7.54M
est: -9.86M (+23.6%)
-53.43M
est: -1.92M (-2,680.3%)
-34.57M
est: -685.8K (-4,940.9%)
-46.78M
est: -661.3K (-6,973.6%)
79.17M
est: -1.29M (+6,236.0%)
-15.89M
est: -362.9K (-4,277.6%)
-32.13M
est: -878.8K (-3,555.8%)
-1.09M
-1.09M – -1.09M
-24.5% YoY
-1.36M
-1.36M – -1.36M
-24.1% YoY
-1.60M
-1.60M – -1.60M
-17.5% YoY
EBIT
2.95M
est: -920.2K (+420.0%)
-33.18M
est: -3.09M (-972.2%)
-47.43M
est: -3.73M (-1,171.8%)
-49.36M
est: -5.21M (-847.1%)
-12.31M
est: -12.54M (+1.8%)
-60.57M
est: -2.44M (-2,379.1%)
-38.29M
est: -871.8K (-4,292.4%)
-50.43M
est: -840.7K (-5,898.1%)
76.13M
est: -6.91M (+1,201.4%)
-21.53M
est: -1.94M (-1,007.5%)
-37.82M
est: -4.71M (-703.2%)
-5.86M
-5.86M – -5.86M
-24.5% YoY
-7.28M
-7.28M – -7.28M
-24.1% YoY
-8.55M
-8.55M – -8.55M
-17.5% YoY
Net Income
5.95M
est: -454.43M (+101.3%)
-35.42M
est: -622.50M (+94.3%)
-51.53M
est: -926.13M (+94.4%)
-54.19M
est: -783.74M (+93.1%)
-18.97M
est: 4.55M (-517.0%)
-67.66M
est: -481.17M (+85.9%)
-55.53M
est: -191.10M (+70.9%)
-71.08M
est: -71.66M (+0.8%)
54.78M
est: 76.69M (-28.6%)
-41.97M
est: -28.70M (-46.3%)
-49.24M
est: -28.70M (-71.6%)
-7.81M
-7.81M – -7.81M
+72.8% YoY
3.32M
3.32M – 3.32M
+142.5% YoY
12.23M
12.23M – 12.23M
+268.6% YoY
SGA
16.60M
est: -8.78M (+289.1%)
30.86M
est: -29.53M (+204.5%)
42.94M
est: -35.59M (+220.7%)
40.25M
est: -49.73M (+180.9%)
39.28M
est: -119.67M (+132.8%)
23.91M
est: -23.31M (+202.6%)
22.06M
est: -8.32M (+365.1%)
25.42M
est: -8.02M (+416.9%)
30.97M
est: -203.88M (+115.2%)
29.87M
est: -57.35M (+152.1%)
30.06M
est: -138.86M (+121.7%)
-172.94M
-172.94M – -172.94M
-24.5% YoY
-214.58M
-214.58M – -214.58M
-24.1% YoY
-252.18M
-252.18M – -252.18M
-17.5% YoY
EPS
11.10
est: -39.95 (+127.8%)
-56.50
est: -54.73 (-3.2%)
-82.19
est: -81.42 (-0.9%)
-78.63
est: -68.90 (-14.1%)
-17.26
est: 0.40 (-4,415.0%)
-50.81
est: -42.30 (-20.1%)
-16.25
est: -16.80 (+3.3%)
-11.67
est: -6.30 (-85.2%)
5.18
est: 5.89 (-12.1%)
-3.69
est: -2.21 (-67.3%)
-3.78
est: -2.21 (-71.4%)
-0.60
-0.60 – -0.60
+72.8% YoY
0.26
0.26 – 0.26
+142.5% YoY
0.94
0.94 – 0.94
+268.6% YoY
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-29 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-05-28 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-05-27 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-05-26 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-05-22 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-05-21 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-05-20 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-05-19 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-05-18 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-05-15 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-05-13 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-05-12 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-05-11 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-05-08 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-05-07 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-05-06 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-05-05 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-05-04 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-04-30 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-04-29 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-04-28 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-04-27 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-04-24 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-04-23 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-04-22 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-04-21 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-04-20 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-04-17 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-04-16 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
-69.95M
OE per share TTM
-5.76
Owner's Yield
-32.04%
Maintenance CapEx ratio
Maint CapEx / Avg PPE
4.7%

Ownership Overview

Ownership breakdown

Ownership breakdown not available.

At a glance
Institutional holders
Total invested
Insider transactions (90d)
0
Beneficial owners (>5%)
0
Beneficial owners (>5%)

No beneficial ownership filings recorded.

Institutional Activity (13F)

Institutional ownership trend

Institutional history not available.

Top institutional holders

Top holders not available.

ETF Ownership

Top ETFs holding this stock Held by 1 ETFs in our universe
# ETF Weight Est. AUM exposure TER
1 iShares Core SPI(R) ETF (CH) CHSPI.SW 0.01% 703.3K 0.10%

Insider Activity

Insider Activity — Latest Quarter

No insider activity available.

Insider buys vs sells (history)

Insider history not available.

Recent insider transactions

No recent insider transactions.

Executive team

Top executives
EBIT / Employee
-484.8K
Shares Outstanding
14.53M

Executive compensation

Executive compensation (annual)

Executive compensation not available.

CEO compensation breakdown

No CEO compensation history available.

Proxy statements

Proxy statements (DEF 14A)

No proxy statements available for this company yet.

Recent SEC filings

Recent SEC filings

No SEC filings available for this company yet.

Executive team

NameTitleCompensationGender
Dario Eklund Chief Executive Officer 1M male
Thomas Meier Founder & Chairman 200.0K
Geert Jan van Daal Chief Commercial Officer male
Marc Schrader Chief Technology Officer male
Andreas Missy Executive Vice President of Corporate Planning & Business Development male
Oliver Kronenberg Chief Legal Officer & Corporate Secretary
Oliver Strub Head of Compliance male
Sarah Holmes-Klotz Global Head of People & Culture female
Shabir Hasham Chief Medical Officer male
Neville Kodkani Head of Global Marketing & Partner Management male
Catherine Ann Isted Chief Financial Officer female
ESG Score History

No data available for this company.

Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend history

Earnings history

Earnings reports

Stock splits