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Rhythm Pharmaceuticals, Inc. (RYTM)
USD107.49
-0.91 (-0.84%)
US NASDAQ Healthcare Biotechnology
Address
222 Berkeley Street 2116
Boston, MA, US
Boston, MA, US
CEO
David Meeker
Website
rhythmtx.com
IPO
2017-10-09
CIK 1649904 ISIN US76243J1051
Description
Rhythm Pharmaceuticals, Inc. is a biopharmaceutical company with commercial products, dedicated to the discovery, development, and market launch of therapies addressing rare genetic conditions that cause obesity. Its leading pharmaceutical, IMCIVREE, functions as a powerful agonist of the melanocortin-4 receptor (MC4R). This medication is indicated for treating obesity stemming from deficiencies in pro-opiomelanocortin (POMC), proprotein convertase subtilisin/kexin type 1 (PCSK1), or the leptin receptor (LEPR), alongside its use in patients with Bardet-Biedl and Alström syndromes. Furthermore, the company is progressing setmelanotide (the active compound in IMCIVREE) through Phase II clinical trials. These studies are evaluating its potential for a broader spectrum of applications, including obesity caused by heterozygous POMC or LEPR deficiencies, steroid receptor coactivator 1 (SRC1) deficiency, SH2B1 deficiency, MC4 receptor deficiency, and obesity associated with Smith-Magenis syndrome, POMC epigenetic disorders, and other MC4R-related conditions. Rhythm Pharmaceuticals holds a collaborative research agreement with the Clinical Registry Investigating Bardet-Biedl Syndrome. The firm, headquartered in Boston, Massachusetts, was established in 2008 and changed its name from Rhythm Metabolic, Inc. to Rhythm Pharmaceuticals, Inc. in October 2015.
News Sentiment (7d)
Based on only 1 article — low confidence
Market Cap & Enterprise Value
Merger & Acquisition History
No mergers or acquisitions recorded for this company.
Technical Outlook
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Signal Summary
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| Indicator | 1D | 1W | 2W | 3W | 1M |
|---|
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
USD107.49
-0.91 (-0.84%)
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Volume Profile
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Liquidity & share structure
Average Volume
807.6K
Beta
1.92
Float Shares
55.45M
Free Float %
81.2%
Price Performance
| 1D | 5D | 1M | 3M | 6M | YTD | 1Y | 3Y | 5Y | 10Y | Max |
|---|---|---|---|---|---|---|---|---|---|---|
| +4.49% | -4.68% | +5.18% | -6.89% | -4.78% | -14.70% | +60.79% | +440.62% | +331.11% | +204.37% | +204.37% |
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From
To
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Annual Monthly Returns
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Daily Returns Distribution
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Revenue flow
Revenue by geography
Revenue by segment
From
To
Revenue composition
From
To
By product
By geography
Financial Statements
Select metrics from the tables below to build your comparison.
Income Statement
Balance Sheet
Cash Flow Statement
Key Metrics
Financial Ratios
Employees
Financial Growth (CAGR)
Market Data
Analyst Consensus (20 ratings, all time)
Buy
Price Targets & DCF
Current price
107.49
Low
125.00
+16.3%
Consensus
140.20
+30.4%
Median
143.00
+33.0%
High
157.00
+46.1%
Ratings Trend (MoM)
94% Bullish
| Rating | 2026-05 | Change |
|---|---|---|
| Strong Buy | 4 | 0 |
| Buy | 11 | 0 |
| Hold | 1 | 0 |
| Sell | 0 | 0 |
| Strong Sell | 0 | 0 |
Price Target Summary
| Period | # Analysts | Avg Target |
|---|---|---|
| Last Month | 1 |
143.00
+33.0%
|
| Last Quarter | 6 |
138.33
+28.7%
|
| Last Year | 21 |
130.57
+21.5%
|
| All Time | 35 |
98.89
-8.0%
|
Quality scores
Altman Z-Score
6.88
Safe zone
Piotroski F-Score
3 / 9
Average
MOAT Score
2 / 10
No MOAT
Composite Rating
D+
Overall Score
1 / 5
Low
DCF Score
1 / 5
Low
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
1 / 5
Low
P/E Score
1 / 5
Low
P/Book Score
1 / 5
Low
Operational MOAT
✗ Below peers
-
Revenue growth Biotechnology: +1.6%+45.8% ★ Q1'26: +83.8% (vs Q1'25)
-
EPS growth Biotechnology: +29.7%+28.3% Q1'26: -2.5% (vs Q1'25)
-
FCF margin FCF growth · Biotechnology: +16.2%-103.9% Q1'26: -73.5% (vs Q1'25)
-
EBIT margin Biotechnology: +0.0%-92.5% Q1'26: -87.1% (vs Q1'25)
-
ROIC Biotechnology: -16.1%— Q1'26: -2,252.3% (vs Q1'25)
-
Share dilution Biotechnology: -3.4%+6.5% Q1'26: +7.8% (vs Q1'25)
-
Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×-1.42× Q1'26: -1.08× (vs Q1'25)
Valuation Multiples
From
To
Consensus Estimates
| Metric |
Dec 2020 actual |
Dec 2021 actual |
Dec 2022 actual |
Dec 2023 actual |
Dec 2024 actual |
Dec 2025 actual |
Dec 2026 12 Rev. Ana. 9 EPS Ana. |
Dec 2027 12 Rev. Ana. 6 EPS Ana. |
Dec 2028 11 Rev. Ana. 7 EPS Ana. |
Dec 2029 5 Rev. Ana. 2 EPS Ana. |
Dec 2030 5 Rev. Ana. 5 EPS Ana. |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue |
—
est: 53.0K (-100.0%)
|
3.15M
est: 3.03M (+4.2%)
|
23.64M
est: 21.41M (+10.4%)
|
77.43M
est: 101.78M (-23.9%)
|
130.13M
est: 126.95M (+2.5%)
|
189.76M
est: 188.99M (+0.4%)
|
298.07M
259.73M – 316.02M
+57.7% YoY
|
540.99M
332.61M – 665.87M
+81.5% YoY
|
873.21M
872.90M – 873.52M
+61.4% YoY
|
1.31B
1.02B – 1.50B
+49.9% YoY
|
1.81B
1.41B – 2.08B
+38.5% YoY
|
| EBITDA |
-135.89M
est: -31.8K (-427,439.9%)
|
-68.45M
est: -1.82M (-3,668.7%)
|
-174.25M
est: -12.84M (-1,256.7%)
|
-168.46M
est: -100.10M (-68.3%)
|
-238.09M
est: -124.86M (-90.7%)
|
-174.12M
est: -185.87M (+6.3%)
|
-293.16M
-310.81M – -255.45M
-57.7% YoY
|
-532.07M
-654.89M – -327.13M
-81.5% YoY
|
-858.82M
-859.12M – -858.52M
-61.4% YoY
|
-1.29B
-1.48B – -1.00B
-49.9% YoY
|
-1.78B
-2.04B – -1.39B
-38.5% YoY
|
| EBIT |
-136.58M
est: -31.8K (-429,610.9%)
|
-69.61M
est: -1.82M (-3,732.5%)
|
-175.92M
est: -12.84M (-1,269.7%)
|
-170.22M
est: -100.25M (-69.8%)
|
-239.65M
est: -125.04M (-91.7%)
|
-175.46M
est: -186.14M (+5.7%)
|
-293.58M
-311.26M – -255.81M
-57.7% YoY
|
-532.83M
-655.83M – -327.60M
-81.5% YoY
|
-860.05M
-860.35M – -859.75M
-61.4% YoY
|
-1.29B
-1.48B – -1.00B
-49.9% YoY
|
-1.79B
-2.05B – -1.39B
-38.5% YoY
|
| Net Income |
-130.73M
est: -184.05M (+29.0%)
|
-69.61M
est: -88.24M (+21.1%)
|
-181.12M
est: -221.55M (+18.2%)
|
-184.68M
est: -260.73M (+29.2%)
|
-260.60M
est: -280.24M (+7.0%)
|
-196.54M
est: -207.84M (+5.4%)
|
-223.30M
-242.13M – -159.65M
-7.4% YoY
|
54.36M
-303.84M – 182.62M
+124.3% YoY
|
268.07M
79.99M – 277.02M
+393.1% YoY
|
406.96M
289.43M – 484.26M
+51.8% YoY
|
673.61M
479.08M – 801.56M
+65.5% YoY
|
| SGA |
46.13M
est: 309.7K (+14,792.5%)
|
68.49M
est: 17.70M (+286.9%)
|
92.03M
est: 125.16M (-26.5%)
|
117.53M
est: 595.66M (-80.3%)
|
144.30M
est: 742.98M (-80.6%)
|
194.94M
est: 1.11B (-82.4%)
|
1.74B
1.52B – 1.85B
+57.7% YoY
|
3.17B
1.95B – 3.90B
+81.5% YoY
|
5.11B
5.11B – 5.11B
+61.4% YoY
|
7.66B
5.96B – 8.78B
+49.9% YoY
|
10.61B
8.25B – 12.16B
+38.5% YoY
|
| EPS |
-2.96
est: -3.02 (+1.9%)
|
-1.37
est: -1.45 (+5.3%)
|
-3.51
est: -3.53 (+0.7%)
|
-3.20
est: -4.38 (+26.9%)
|
-4.34
est: -4.32 (-0.4%)
|
-3.11
est: -3.17 (+2.0%)
|
-3.12
-3.73 – -2.46
+1.6% YoY
|
-0.70
-4.68 – 2.81
+77.5% YoY
|
2.39
1.23 – 4.26
+440.4% YoY
|
6.26
4.45 – 7.45
+161.9% YoY
|
10.37
7.37 – 12.33
+65.5% YoY
|
Recent Grade Changes (3M)
| Date | Firm | Previous | New Grade | Action |
|---|---|---|---|---|
| 2026-05-07 | Canaccord Genuity | Buy | Buy | Maintain |
| 2026-05-06 | RBC Capital | Outperform | Outperform | Maintain |
Historical Ratings (3M)
| Date | Rating | Overall | DCF | ROE | ROA | D/E | P/E | P/B |
|---|---|---|---|---|---|---|---|---|
| 2026-05-12 | D+ | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 |
| 2026-05-11 | D+ | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 |
| 2026-05-08 | D+ | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 |
| 2026-05-07 | C- | 1/5 | 1/5 | 1/5 | 1/5 | 3/5 | 1/5 | 1/5 |
| 2026-05-06 | C- | 1/5 | 1/5 | 1/5 | 1/5 | 3/5 | 1/5 | 1/5 |
| 2026-05-05 | C- | 1/5 | 1/5 | 1/5 | 1/5 | 3/5 | 1/5 | 1/5 |
| 2026-05-04 | D+ | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 |
| 2026-05-01 | D+ | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 |
| 2026-04-30 | D+ | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 |
| 2026-04-29 | D+ | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 |
| 2026-04-28 | D+ | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 |
| 2026-04-27 | D+ | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 |
| 2026-04-24 | D+ | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 |
| 2026-04-23 | D+ | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 |
| 2026-04-22 | D+ | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 |
| 2026-04-21 | D+ | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 |
| 2026-04-20 | D+ | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 |
| 2026-04-17 | D+ | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 |
| 2026-04-16 | D+ | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 |
| 2026-04-15 | D+ | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 |
Owner Earnings
Owner's Earnings (history)
From
To
Owner alignment
Owner's Earnings TTM
-115.01M
OE per share TTM
-1.74
Owner's Yield
-1.85%
Maintenance CapEx ratio
—
Maint CapEx / Avg PPE
6.8%
Ownership Overview
Ownership breakdown
At a glance
Institutional holders
53
Total invested
138.02M
Insider transactions (90d)
0
Beneficial owners (>5%)
24
Beneficial owners (>5%)
| # | Reporting person | Amount owned | % of class | Sole voting | Shared voting | Sole dispositive | Shared dispositive | Type | Citizenship | Filing date | SEC filing |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Baker Bros. Advisors LP | 6.06M | 10.90% | 6.06M | — | 6.06M | — | IA, PN | Delaware | 2022-10-07 | ↗ |
| 2 | s. | 5.57M | 11.14% | 5.57M | — | 5.57M | — | IA | 177 E. Colorado Blvd., 11th Floor, Pasadena, CA 91105 | 2021-03-08 | ↗ |
| 3 | Joseph Edelman | 5.44M | 8.60% | — | 5.44M | — | 5.44M | IN | Delaware | 2024-11-14 | ↗ |
| 4 | Perceptive Advisors LLC | 5.44M | 8.60% | — | 5.44M | — | 5.44M | OO | Delaware | 2024-11-14 | ↗ |
| 5 | Federated Hermes, Inc. | 5.07M | 10.06% | 5.07M | — | 5.07M | — | HC | Citizenship or place of Organization | 2022-04-11 | ↗ |
| 6 | J. Christopher Donahue | 5.07M | 10.06% | — | 5.07M | — | 5.07M | IN | Citizenship or place of Organization | 2022-04-11 | ↗ |
| 7 | Rhodora J. Donahue | 5.07M | 10.06% | — | 5.07M | — | 5.07M | IN | Citizenship or place of Organization | 2022-04-11 | ↗ |
| 8 | Thomas R. Donahue | 5.07M | 10.06% | — | 5.07M | — | 5.07M | IN | Citizenship or place of Organization | 2022-04-11 | ↗ |
| 9 | Voting Shares Irrevocable Trust | 5.07M | 10.06% | 5.07M | — | 5.07M | — | OO | Citizenship or place of Organization | 2022-04-11 | ↗ |
| 10 | (. | 4.34M | 9.82% | 4.34M | — | 4.34M | — | IA | Citizenship or Place of Organization | 2021-02-12 | ↗ |
| 11 | Perceptive Life Sciences Master Fund, Ltd. | 3.98M | 6.30% | — | 3.98M | — | 3.98M | CO | Delaware | 2024-11-14 | ↗ |
| 12 | (1) BlackRock, Inc. | 3.72M | 6.60% | 3.68M | — | 3.72M | — | HC | Delaware | 2023-02-03 | ↗ |
| 13 | PRIMECAP Management Company 95-3868081 | 3.54M | 8.04% | 3.54M | — | 3.54M | — | IA | — | 2020-04-24 | ↗ |
| 14 | Wellington Group Holdings LLP | 3.32M | 7.56% | — | 3.08M | — | — | HC | Massachusetts | 2020-01-28 | ↗ |
| 15 | Wellington Investment Advisors Holdings LLP | 3.32M | 7.56% | — | 3.08M | — | — | HC | Massachusetts | 2020-01-28 | ↗ |
| 16 | The Vanguard Group - 23-1945930 | 3.23M | 5.46% | — | 93.4K | 3.09M | — | IA | Pennsylvania | 2024-02-13 | ↗ |
| 17 | Wellington Management Company LLP | 3.19M | 7.25% | — | 3.03M | — | — | IA | Massachusetts | 2020-01-28 | ↗ |
| 18 | STATE STREET CORPORATION | 3.18M | 5.64% | — | 3.14M | — | 3.18M | HC | — | 2023-02-03 | ↗ |
| 19 | EIN #00-0000000 | 3.13M | 6.20% | — | 3.13M | — | 3.13M | IA, HC | Jersey, Channel Islands | 2022-02-10 | ↗ |
| 20 | GOLDMAN SACHS & CO. LLC | 3.06M | 6.10% | 13.00 | 3.06M | — | 3.06M | BD, IA, OO | New York | 2022-01-24 | ↗ |
| 21 | THE GOLDMAN SACHS GROUP, INC. | 3.06M | 6.10% | 13.00 | 3.06M | — | 3.06M | HC, CO | New York | 2022-01-24 | ↗ |
| 22 | SSGA FUNDS MANAGEMENT, INC. | 2.93M | 5.21% | — | 2.93M | — | 2.93M | IA | — | 2023-02-03 | ↗ |
| 23 | Wellington Management Group LLP | 2.10M | 4.75% | — | 1.93M | — | 2.10M | HC | Massachusetts | 2021-02-04 | ↗ |
| 24 | Perceptive Discovery ID LP | 1.46M | 2.30% | — | 1.46M | — | 1.46M | PN | Delaware | 2024-11-14 | ↗ |
Institutional Activity (13F)
Institutional ownership trend
From
To
13F snapshot — 2026 Q1
Investors holding
53
-229 vs prev Q
New positions
12
Closed positions
237
Increased
31
Reduced
10
Put/Call ratio
0.00
Calls held
—
Puts held
—
Top institutional holders
| # | Investor | Shares / Δ | Mkt value / Δ | Own% / Δ | Weight% / Δ | Avg px / Perf. | Hold / Status |
|---|---|---|---|---|---|---|---|
| 1 | — | 67.6K +67.6K (+100.0%) | 7.23B +7.2B (+100.0%) | 0.11% +0.105 pp | 4.24% +4.243 pp | USD107.04 +0.0% | 1 qtrs NEW |
| 2 | RA CAPITAL MANAGEMENT, L.P. | 6.67M +985.5K (+17.3%) | 713.62M +139.9M (+24.4%) | 10.36% +1.440 pp | 7.31% +0.241 pp | USD39.94 +168.0% | 31 qtrs — |
| 3 | BLACKROCK, INC. | 6.30M -4.9K (-0.1%) | 674.07M +37.6M (+5.9%) | 9.79% -0.109 pp | 0.01% +0.000 pp | USD52.69 +103.2% | 6 qtrs — |
| 4 | VANGUARD GROUP INC | 6.21M +1.2M (+24.3%) | 664.82M +160.2M (+31.8%) | 9.65% +1.807 pp | 0.01% +0.002 pp | USD60.55 +76.8% | 33 qtrs — |
| 5 | BAKER BROS. ADVISORS LP | 5.60M +— (+0.0%) | 599.90M +33.9M (+6.0%) | 8.71% -0.091 pp | 3.51% -0.577 pp | USD24.92 +329.5% | 33 qtrs — |
| 6 | PRIMECAP MANAGEMENT CO/CA/ | 3.48M -784.2K (-18.4%) | 372.36M -58.1M (-13.5%) | 5.41% -1.288 pp | 0.28% -0.048 pp | USD20.60 +419.6% | 26 qtrs — |
| 7 | NEA MANAGEMENT COMPANY, LLC | 2.91M +— (+0.0%) | 311.48M +17.6M (+6.0%) | 4.52% -0.047 pp | 15.88% -0.244 pp | USD29.06 +268.3% | 33 qtrs — |
| 8 | PERCEPTIVE ADVISORS LLC | 2.55M -309.2K (-10.8%) | 272.57M -15.8M (-5.5%) | 3.96% -0.527 pp | 4.86% -3.469 pp | USD51.84 +106.5% | 10 qtrs — |
| 9 | STATE STREET CORP | 2.20M +170.0K (+8.4%) | 235.34M +30.5M (+14.9%) | 3.42% +0.231 pp | 0.01% +0.001 pp | USD39.72 +169.5% | 33 qtrs — |
| 10 | GOLDMAN SACHS GROUP INC | 1.83M -62.8K (-3.3%) | 195.98M +4.7M (+2.5%) | 2.85% -0.128 pp | 0.02% +0.001 pp | USD29.28 +265.6% | 31 qtrs — |
| 11 | FMR LLC | 1.71M -438.9K (-20.5%) | 182.64M -34.0M (-15.7%) | 2.65% -0.717 pp | 0.01% -0.002 pp | USD58.18 +84.0% | 33 qtrs — |
| 12 | FEDERATED HERMES, INC. | 1.62M -104.0K (-6.0%) | 173.82M -683.2K (-0.4%) | 2.52% -0.190 pp | 0.29% -0.018 pp | USD25.61 +318.0% | 33 qtrs — |
| 13 | PRICE T ROWE ASSOCIATES INC /MD/ | 1.56M +161.0K (+11.5%) | 167.07M +25.7M (+18.2%) | 2.43% +0.228 pp | 0.02% +0.003 pp | USD55.90 +91.5% | 21 qtrs — |
| 14 | JPMORGAN CHASE & CO | 1.42M +235.9K (+19.9%) | 152.42M +32.4M (+27.0%) | 2.21% +0.347 pp | 0.01% +0.002 pp | USD79.80 +34.1% | 33 qtrs — |
| 15 | GEODE CAPITAL MANAGEMENT, LLC | 1.38M +12.9K (+0.9%) | 147.28M +9.6M (+7.0%) | 2.14% -0.002 pp | 0.01% +0.000 pp | USD29.02 +268.8% | 33 qtrs — |
| 16 | DRIEHAUS CAPITAL MANAGEMENT LLC | 1.29M -98.6K (-7.1%) | 137.57M -2.2M (-1.6%) | 2.00% -0.176 pp | 0.93% -0.067 pp | USD46.57 +129.8% | 14 qtrs — |
| 17 | WESTFIELD CAPITAL MANAGEMENT CO LP | 1.27M +198.2K (+18.5%) | 135.64M +27.7M (+25.6%) | 1.97% +0.291 pp | 0.57% +0.112 pp | USD62.95 +70.0% | 4 qtrs — |
| 18 | POLAR CAPITAL HOLDINGS PLC | 1.19M -59.5K (-4.8%) | 126.88M +1.2M (+0.9%) | 1.84% -0.113 pp | 0.49% -0.115 pp | USD46.88 +128.3% | 14 qtrs — |
| 19 | JANUS HENDERSON GROUP PLC | 1.13M -34.8K (-3.0%) | 120.59M +3.4M (+2.9%) | 1.75% -0.073 pp | 0.05% +0.001 pp | USD44.85 +138.7% | 33 qtrs — |
| 20 | CHECKPOINT CAPITAL L.P. | 992.2K +228.5K (+29.9%) | 106.21M +29.1M (+37.7%) | 1.54% +0.343 pp | 33.18% +7.339 pp | USD62.99 +69.9% | 9 qtrs — |
| 21 | CAPITAL RESEARCH GLOBAL INVESTORS | 985.1K +386.8K (+64.7%) | 105.44M +45.0M (+74.5%) | 1.53% +0.592 pp | 0.02% +0.008 pp | USD103.37 +3.6% | 2 qtrs — |
| 22 | ALLIANCEBERNSTEIN L.P. | 930.2K -49.4K (-5.0%) | 99.57M +634.1K (+0.6%) | 1.45% -0.093 pp | 0.03% +0.000 pp | USD95.96 +11.5% | 11 qtrs — |
| 23 | JENNISON ASSOCIATES LLC | 918.6K +507.0K (+123.2%) | 98.32M +56.8M (+136.6%) | 1.43% +0.781 pp | 0.06% +0.035 pp | USD104.33 +2.6% | 2 qtrs — |
| 24 | FRANKLIN RESOURCES INC | 695.7K +128.0K (+22.5%) | 74.47M +17.1M (+29.9%) | 1.08% +0.190 pp | 0.02% +0.004 pp | USD64.37 +66.3% | 9 qtrs — |
| 25 | ROCK SPRINGS CAPITAL MANAGEMENT LP | 695.0K -22.1K (-3.1%) | 74.39M +2.0M (+2.7%) | 1.08% -0.046 pp | 3.81% -0.417 pp | USD18.96 +464.6% | 33 qtrs — |
| 26 | WOODLINE PARTNERS LP | 688.8K +108.6K (+18.7%) | 73.73M +15.1M (+25.8%) | 1.07% +0.159 pp | 0.29% +0.010 pp | USD73.71 +45.2% | 3 qtrs — |
| 27 | MORGAN STANLEY | 651.4K +186.2K (+40.0%) | 69.73M +22.7M (+48.4%) | 1.01% +0.282 pp | 0.00% +0.001 pp | USD58.38 +83.4% | 33 qtrs — |
| 28 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 621.6K +77.6K (+14.3%) | 66.53M +11.6M (+21.1%) | 0.97% +0.112 pp | 0.10% +0.014 pp | USD81.01 +32.1% | 3 qtrs — |
| 29 | LORD, ABBETT & CO. LLC | 619.5K +43.6K (+7.6%) | 66.32M +8.1M (+14.0%) | 0.96% +0.058 pp | 0.20% +0.030 pp | USD85.98 +24.5% | 9 qtrs — |
| 30 | PICTET ASSET MANAGEMENT HOLDING SA | 614.7K -68.4K (-10.0%) | 66.19M -2.8M (-4.0%) | 0.96% -0.117 pp | 0.06% -0.002 pp | USD71.85 +49.0% | 9 qtrs — |
| 31 | UBS ASSET MANAGEMENT AMERICAS INC | 549.0K +111.5K (+25.5%) | 58.77M +14.6M (+33.0%) | 0.85% +0.166 pp | 0.01% +0.003 pp | USD77.24 +38.6% | 23 qtrs — |
| 32 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 532.4K +4.5K (+0.9%) | 56.99M +3.7M (+6.9%) | 0.83% -0.002 pp | 0.01% +0.000 pp | USD36.29 +195.0% | 33 qtrs — |
| 33 | CLEARBRIDGE INVESTMENTS, LLC | 506.1K +21.4K (+4.4%) | 54.17M +5.2M (+10.7%) | 0.79% +0.025 pp | 0.04% +0.007 pp | USD77.91 +37.4% | 3 qtrs — |
| 34 | LOOMIS SAYLES & CO L P | 503.9K -23.5K (-4.5%) | 53.94M +671.5K (+1.3%) | 0.78% -0.045 pp | 0.07% +0.002 pp | USD52.39 +104.3% | 6 qtrs — |
| 35 | SIREN, L.L.C. | 500.0K +— (+0.0%) | 53.52M +3.0M (+6.0%) | 0.78% -0.008 pp | 1.60% -0.379 pp | USD64.34 +66.4% | 4 qtrs — |
| 36 | NORTHERN TRUST CORP | 488.2K -22.7K (-4.4%) | 52.26M +662.2K (+1.3%) | 0.76% -0.044 pp | 0.01% +0.000 pp | USD22.39 +378.1% | 33 qtrs — |
| 37 | INTEGRAL HEALTH ASSET MANAGEMENT, LLC | 475.0K +255.0K (+115.9%) | 50.84M +28.6M (+128.8%) | 0.74% +0.393 pp | 2.52% +1.021 pp | USD94.69 +13.0% | 5 qtrs — |
| 38 | POINT72 ASSET MANAGEMENT, L.P. | 429.4K +429.4K (+100.0%) | 45.97M +46.0M (+100.0%) | 0.67% +0.667 pp | 0.05% +0.051 pp | USD107.04 +0.0% | 4 qtrs — |
| 39 | UBS GROUP AG | 427.2K +6.9K (+1.6%) | 45.73M +3.3M (+7.7%) | 0.66% +0.004 pp | 0.01% +0.001 pp | USD72.20 +48.3% | 33 qtrs — |
| 40 | RENAISSANCE TECHNOLOGIES LLC | 341.2K -205.4K (-37.6%) | 36.52M -18.7M (-33.8%) | 0.53% -0.328 pp | 0.06% -0.016 pp | USD78.95 +35.6% | 4 qtrs — |
| 41 | OPALEYE MANAGEMENT INC. | 330.0K -131.7K (-28.5%) | 35.32M -11.3M (-24.2%) | 0.51% -0.212 pp | 4.66% -1.932 pp | USD15.41 +594.6% | 15 qtrs — |
| 42 | QUBE RESEARCH & TECHNOLOGIES LTD | 310.9K +72.1K (+30.2%) | 33.28M +9.2M (+38.0%) | 0.48% +0.108 pp | 0.03% +0.009 pp | USD67.21 +59.3% | 5 qtrs — |
| 43 | BANK OF NEW YORK MELLON CORP | 301.1K +118.7K (+65.1%) | 32.23M +13.8M (+75.0%) | 0.47% +0.182 pp | 0.01% +0.002 pp | USD60.19 +77.8% | 33 qtrs — |
| 44 | FIRST LIGHT ASSET MANAGEMENT, LLC | 295.8K +115.4K (+63.9%) | 31.67M +13.4M (+73.7%) | 0.46% +0.176 pp | 2.42% +0.703 pp | USD103.35 +3.6% | 2 qtrs — |
| 45 | INVESCO LTD. | 291.2K +147.6K (+102.8%) | 31.16M +16.7M (+115.0%) | 0.45% +0.227 pp | 0.00% +0.003 pp | USD90.46 +18.3% | 13 qtrs — |
| 46 | CANDRIAM S.C.A. | 287.9K +66.0K (+29.8%) | 30.82M +8.4M (+37.5%) | 0.45% +0.099 pp | 0.15% +0.036 pp | USD60.69 +76.4% | 7 qtrs — |
| 47 | SOFINNOVA INVESTMENTS, INC. | 271.4K +24.4K (+9.9%) | 29.05M +4.1M (+16.5%) | 0.42% +0.034 pp | 1.25% -0.111 pp | USD60.36 +77.3% | 6 qtrs — |
| 48 | SIO CAPITAL MANAGEMENT, LLC | 265.7K +265.7K (+100.0%) | 28.44M +28.4M (+100.0%) | 0.41% +0.413 pp | 4.47% +4.474 pp | USD107.04 +0.0% | 1 qtrs NEW |
| 49 | ARTISAN PARTNERS LIMITED PARTNERSHIP | 263.6K +26.8K (+11.3%) | 28.21M +4.3M (+18.0%) | 0.41% +0.038 pp | 0.04% +0.008 pp | USD76.58 +39.8% | 3 qtrs — |
| 50 | AMERIPRISE FINANCIAL INC | 261.2K +123.2K (+89.3%) | 27.95M +14.0M (+100.6%) | 0.41% +0.189 pp | 0.01% +0.003 pp | USD77.38 +38.3% | 15 qtrs — |
| 51 | WELLINGTON MANAGEMENT GROUP LLP | 250.2K +225.7K (+922.0%) | 26.78M +24.3M (+983.2%) | 0.39% +0.350 pp | 0.00% +0.004 pp | USD99.96 +7.1% | 33 qtrs — |
| 52 | VOYA INVESTMENT MANAGEMENT LLC | 249.9K +28.3K (+12.8%) | 26.75M +4.4M (+19.5%) | 0.39% +0.040 pp | 0.03% +0.004 pp | USD62.80 +70.4% | 25 qtrs — |
| 53 | ORBIMED ADVISORS LLC | 239.8K +24.6K (+11.5%) | 25.67M +3.9M (+18.1%) | 0.37% +0.035 pp | 0.53% +0.014 pp | USD35.80 +199.0% | 10 qtrs — |
| 54 | HOOD RIVER CAPITAL MANAGEMENT LLC | 237.0K +1.2K (+0.5%) | 25.37M +1.6M (+6.5%) | 0.37% -0.002 pp | 0.28% -0.003 pp | USD52.84 +102.6% | 6 qtrs — |
| 55 | BANK OF AMERICA CORP /DE/ | 224.5K -8.7K (-3.7%) | 24.03M +482.9K (+2.1%) | 0.35% -0.017 pp | 0.00% +0.000 pp | USD51.04 +109.7% | 33 qtrs — |
| 56 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 212.8K -46.8K (-18.0%) | 22.78M -3.4M (-13.1%) | 0.33% -0.077 pp | 0.00% 0.000 pp | USD88.67 +20.7% | 16 qtrs — |
| 57 | LOGOS GLOBAL MANAGEMENT LP | 190.0K -10.0K (-5.0%) | 20.34M +139.6K (+0.7%) | 0.30% -0.019 pp | 1.23% -0.582 pp | USD76.42 +40.1% | 3 qtrs — |
| 58 | MILLENNIUM MANAGEMENT LLC | 186.7K +53.5K (+40.2%) | 19.99M +6.5M (+48.6%) | 0.29% +0.081 pp | 0.01% +0.003 pp | USD68.45 +56.4% | 6 qtrs — |
| 59 | BNP PARIBAS ARBITRAGE, SNC | 164.6K -59.1K (-26.4%) | 17.61M -5.0M (-22.0%) | 0.26% -0.096 pp | 0.01% -0.004 pp | USD80.23 +33.4% | 33 qtrs — |
| 60 | CITADEL ADVISORS LLC | 153.3K +20.7K (+15.6%) | 16.41M +3.0M (+22.5%) | 0.24% +0.030 pp | 0.00% +0.000 pp | USD101.81 +5.1% | 16 qtrs — |
| 61 | CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD. | 149.4K +28.1K (+23.2%) | 15.99M +3.7M (+30.6%) | 0.23% +0.042 pp | 0.04% +0.003 pp | USD69.66 +53.7% | 11 qtrs — |
| 62 | FIRST TURN MANAGEMENT, LLC | 146.3K +146.3K (+100.0%) | 15.66M +15.7M (+100.0%) | 0.23% +0.227 pp | 1.79% +1.789 pp | USD107.04 +0.0% | 1 qtrs NEW |
| 63 | JANE STREET GROUP, LLC | 137.7K +64.7K (+88.6%) | 14.74M +7.4M (+99.9%) | 0.21% +0.099 pp | 0.00% +0.001 pp | USD79.39 +34.8% | 6 qtrs — |
| 64 | M&G PLC | 137.1K +137.1K (+100.0%) | 14.67M +14.7M (+100.0%) | 0.21% +0.213 pp | 0.08% +0.075 pp | USD107.04 +0.0% | 1 qtrs NEW |
| 65 | SILVERARC CAPITAL MANAGEMENT, LLC | 136.0K -234.0K (-63.3%) | 14.55M -22.8M (-61.1%) | 0.21% -0.370 pp | 2.02% -3.018 pp | USD40.04 +167.3% | 11 qtrs — |
| 66 | RUSSELL INVESTMENTS GROUP, LTD. | 134.2K -23.5K (-14.9%) | 14.36M -1.6M (-9.8%) | 0.21% -0.039 pp | 0.02% -0.002 pp | USD62.08 +72.4% | 8 qtrs — |
| 67 | BARCLAYS PLC | 131.4K +25.0K (+23.5%) | 14.07M +8.5M (+152.4%) | 0.20% +0.037 pp | 0.00% +0.002 pp | USD66.51 +60.9% | 33 qtrs — |
| 68 | DEUTSCHE BANK AG\ | 129.1K +12.4K (+10.6%) | 13.82M +2.0M (+17.2%) | 0.20% +0.017 pp | 0.00% +0.001 pp | USD83.23 +28.6% | 13 qtrs — |
| 69 | UNIVERSAL- BETEILIGUNGS- UND SERVICEGESELLSCHAFT MBH | 123.5K +22.2K (+21.9%) | 13.22M +3.0M (+29.1%) | 0.19% +0.033 pp | 0.02% +0.005 pp | USD67.00 +59.8% | 5 qtrs — |
| 70 | NUVEEN, LLC | 115.9K -2.0K (-1.7%) | 12.41M +496.4K (+4.2%) | 0.18% -0.005 pp | 0.00% +0.000 pp | USD52.97 +102.1% | 4 qtrs — |
| 71 | CAPITAL WORLD INVESTORS | 115.7K +115.7K (+100.0%) | 12.38M +12.4M (+100.0%) | 0.18% +0.180 pp | 0.00% +0.002 pp | USD107.04 +0.0% | 1 qtrs NEW |
| 72 | SWISS NATIONAL BANK | 111.3K +9.0K (+8.8%) | 11.91M +1.6M (+15.3%) | 0.17% +0.012 pp | 0.01% +0.001 pp | USD40.41 +164.9% | 31 qtrs — |
| 73 | NEW YORK STATE COMMON RETIREMENT FUND | 93.7K +18.5K (+24.7%) | 10.03M +2.4M (+32.2%) | 0.15% +0.028 pp | 0.01% +0.004 pp | USD72.18 +48.3% | 33 qtrs — |
| 74 | FIRST TRUST ADVISORS LP | 88.5K +7.6K (+9.4%) | 9.47M +1.3M (+16.0%) | 0.14% +0.011 pp | 0.01% +0.001 pp | USD57.39 +86.5% | 7 qtrs — |
| 75 | ALGERT GLOBAL LLC | 88.3K -52.0K (-37.1%) | 9.45M -4.7M (-33.3%) | 0.14% -0.083 pp | 0.15% -0.090 pp | USD75.29 +42.2% | 11 qtrs — |
| 76 | AXIOM INVESTORS LLC /DE | 83.6K +523.0 (+0.6%) | 8.94M +558.3K (+6.7%) | 0.13% -0.001 pp | 0.08% +0.017 pp | USD77.29 +38.5% | 3 qtrs — |
| 77 | ZWEIG-DIMENNA ASSOCIATES LLC | 81.6K +81.6K (+100.0%) | 8.73M +8.7M (+100.0%) | 0.13% +0.127 pp | 0.54% +0.542 pp | USD107.04 +0.0% | 1 qtrs NEW |
| 78 | SUMMITTX CAPITAL, L.P. | 80.7K +68.9K (+580.2%) | 8.64M +7.4M (+620.9%) | 0.13% +0.107 pp | 0.26% +0.211 pp | USD99.57 +7.5% | 4 qtrs — |
| 79 | EXODUSPOINT CAPITAL MANAGEMENT, LP | 75.1K +75.1K (+100.0%) | 8.04M +8.0M (+100.0%) | 0.12% +0.117 pp | 0.06% +0.063 pp | USD107.04 +0.0% | 1 qtrs NEW |
| 80 | NEUBERGER BERMAN GROUP LLC | 73.6K -11.5K (-13.6%) | 7.88M -720.8K (-8.4%) | 0.11% -0.019 pp | 0.01% 0.000 pp | USD55.13 +94.2% | 4 qtrs — |
| 81 | WELLS FARGO & COMPANY/MN | 72.6K +25.5K (+54.1%) | 7.77M +3.0M (+63.3%) | 0.11% +0.039 pp | 0.00% +0.001 pp | USD67.27 +59.1% | 33 qtrs — |
| 82 | BALYASNY ASSET MANAGEMENT L.P. | 72.3K -277.7K (-79.3%) | 7.74M -27.6M (-78.1%) | 0.11% -0.437 pp | 0.01% -0.035 pp | USD93.75 +14.2% | 5 qtrs — |
| 83 | RHUMBLINE ADVISERS | 71.2K -10.9K (-13.2%) | 7.62M -665.5K (-8.0%) | 0.11% -0.018 pp | 0.01% -0.001 pp | USD22.76 +370.3% | 11 qtrs — |
| 84 | AQR CAPITAL MANAGEMENT LLC | 70.0K -9.7K (-12.2%) | 7.50M -559.3K (-6.9%) | 0.11% -0.016 pp | 0.00% -0.001 pp | USD69.98 +53.0% | 11 qtrs — |
| 85 | NORGES BANK | 66.2K +66.2K (+100.0%) | 7.09M +7.1M (+100.0%) | 0.10% +0.103 pp | 0.00% +0.001 pp | USD107.04 +0.0% | 1 qtrs NEW |
| 86 | CASTLEARK MANAGEMENT LLC | 64.5K +21.9K (+51.6%) | 6.90M +2.6M (+60.7%) | 0.10% +0.033 pp | 0.20% +0.082 pp | USD103.05 +3.9% | 2 qtrs — |
| 87 | VOLORIDGE INVESTMENT MANAGEMENT, LLC | 60.6K -307.7K (-83.6%) | 6.48M -30.7M (-82.6%) | 0.09% -0.484 pp | 0.02% -0.102 pp | USD50.26 +113.0% | 14 qtrs — |
| 88 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 59.6K -1.3K (-2.1%) | 6.37M +219.9K (+3.6%) | 0.09% -0.003 pp | 0.01% +0.000 pp | USD39.93 +168.1% | 11 qtrs — |
| 89 | PDT PARTNERS, LLC | 59.4K -26.7K (-31.0%) | 6.36M -2.3M (-26.9%) | 0.09% -0.043 pp | 0.41% -0.136 pp | USD52.76 +102.9% | 7 qtrs — |
| 90 | STEMPOINT CAPITAL LP | 58.9K -32.5K (-35.6%) | 6.31M -2.9M (-31.7%) | 0.09% -0.052 pp | 1.08% -0.769 pp | USD61.67 +73.6% | 6 qtrs — |
| 91 | EAM INVESTORS, LLC | 57.3K -1.2K (-2.0%) | 6.14M +325.9K (+5.6%) | 0.09% -0.003 pp | 0.68% +0.017 pp | USD100.99 +6.0% | 5 qtrs — |
| 92 | RAFFERTY ASSET MANAGEMENT, LLC | 55.5K -208.0 (-0.4%) | 5.94M +314.9K (+5.6%) | 0.09% -0.001 pp | 0.02% +0.002 pp | USD40.26 +165.9% | 14 qtrs — |
| 93 | LEGAL & GENERAL GROUP PLC | 55.1K -2.3K (-4.0%) | 5.90M +100.8K (+1.7%) | 0.09% -0.005 pp | 0.00% +0.000 pp | USD30.68 +248.9% | 33 qtrs — |
| 94 | TD ASSET MANAGEMENT INC | 55.1K -4.5K (-7.6%) | 5.89M -122.8K (-2.0%) | 0.09% -0.008 pp | 0.00% 0.000 pp | USD53.81 +98.9% | 9 qtrs — |
| 95 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 53.5K +4.6K (+9.4%) | 5.73M +788.8K (+16.0%) | 0.08% +0.006 pp | 0.01% +0.001 pp | USD38.39 +178.8% | 33 qtrs — |
| 96 | GRANAHAN INVESTMENT MANAGEMENT, LLC | 53.5K +3.7K (+7.5%) | 5.72M +699.5K (+13.9%) | 0.08% +0.005 pp | 0.25% +0.039 pp | USD72.30 +48.0% | 3 qtrs — |
| 97 | PRUDENTIAL FINANCIAL INC | 53.1K -19.9K (-27.2%) | 5.69M -1.7M (-22.8%) | 0.08% -0.032 pp | 0.01% -0.002 pp | USD96.67 +10.7% | 6 qtrs — |
| 98 | ADAR1 CAPITAL MANAGEMENT, LLC | 51.3K +1.8K (+3.6%) | 5.50M +490.2K (+9.8%) | 0.08% +0.002 pp | 0.40% -0.067 pp | USD62.26 +71.9% | 8 qtrs — |
| 99 | NAN FUNG GROUP HOLDINGS LTD | 49.1K +— (+0.0%) | 5.26M +297.2K (+6.0%) | 0.08% -0.001 pp | 4.71% -3.615 pp | USD29.68 +260.6% | 13 qtrs — |
| 100 | VICTORY CAPITAL MANAGEMENT INC | 45.4K +2.5K (+5.8%) | 4.86M +526.8K (+12.2%) | 0.07% +0.003 pp | 0.00% +0.000 pp | USD82.70 +29.4% | 10 qtrs — |
Ownership breakdown by holder
Insider Activity
Insider Activity — Latest Quarter
Ratio by transactions
1.50
Neutral
Ratio by volume
2.33
Bullish
Buys
3
Sells
2
Shares acquired
29.9K
Shares disposed
12.9K
Cash buys
—
Cash sales
—
Net activity
+17,065
Insider buys vs sells (history)
From
To
Recent insider transactions
From
To
| Date | Person | Role | Transaction | A/D | Security | Shares | Price | Value | Owned after | D/I | Filing |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026-04-01 | Popovits Kimberly J | Director | A-Award | A | Stock Options (Right to Buy) | 10,257 | 88.12 | 903.8K | 10,257 | D | ↗ |
| 2026-04-01 | Mazabraud Yann | Officer | M-Exempt | A | Common Stock | 12,875 | 0.00 | — | 66,030 | D | ↗ |
| 2026-03-12 | Mathers Edward T | Director | J-Other | A | Common Stock | 4,199 | 0.00 | — | 14,168 | I | ↗ |
| 2026-03-04 | German Christopher Paul | Officer | M-Exempt | A | Common Stock | 1,500 | 17.97 | 27.0K | 5,753 | D | ↗ |
| 2026-03-02 | Smith Hunter C | Officer | M-Exempt | A | Common Stock | 6,099 | 6.80 | 41.5K | 116,611 | D | ↗ |
| 2026-03-02 | Mazabraud Yann | Officer | A-Award | A | Stock Options (Right to Buy) | 35,000 | 94.94 | 3.32M | 35,000 | D | ↗ |
| 2026-03-02 | Mathers Edward T | Director | J-Other | A | Common Stock | 4,198 | 0.00 | — | 9,969 | I | ↗ |
| 2026-03-01 | German Christopher Paul | Officer | M-Exempt | A | Common Stock | 1,162 | 0.00 | — | 4,595 | D | ↗ |
| 2026-02-19 | Smith Hunter C | Officer | S-Sale | D | Common Stock | 585 | 103.28 | 60.4K | 110,512 | D | ↗ |
| 2026-02-17 | Smith Hunter C | Officer | S-Sale | D | Common Stock | 200 | 103.84 | 20.8K | 114,897 | D | ↗ |
| 2026-02-14 | Mazabraud Yann | Officer | M-Exempt | A | Common Stock | 10,000 | 0.00 | — | 53,155 | D | ↗ |
| 2026-02-12 | Smith Hunter C | Officer | S-Sale | D | Common Stock | 100 | 100.10 | 10.0K | 118,466 | D | ↗ |
| 2026-02-11 | Smith Hunter C | Officer | A-Award | A | Restricted Stock Units | 25,000 | 0.00 | — | 25,000 | D | ↗ |
| 2026-02-11 | Shulman Joseph | Officer | A-Award | A | Restricted Stock Units | 15,000 | 0.00 | — | 15,000 | D | ↗ |
| 2026-02-11 | Meeker David P | Director / Officer | A-Award | A | Stock Options (Right to Buy) | 107,850 | 98.47 | 10.62M | 107,850 | D | ↗ |
| 2026-02-11 | Mazabraud Yann | Officer | A-Award | A | Restricted Stock Units | 23,350 | 0.00 | — | 23,350 | D | ↗ |
| 2026-02-11 | Lee Jennifer Kayden | Officer | A-Award | A | Stock Options (Right to Buy) | 32,500 | 98.47 | 3.20M | 32,500 | D | ↗ |
| 2026-02-11 | German Christopher Paul | Officer | A-Award | A | Restricted Stock Units | 5,215 | 0.00 | — | 5,215 | D | ↗ |
| 2026-02-11 | Garfield Alastair | Officer | A-Award | A | Stock Options (Right to Buy) | 25,000 | 98.47 | 2.46M | 25,000 | D | ↗ |
| 2026-02-11 | Cramer Pamela J. | Officer | A-Award | A | Stock Options (Right to Buy) | 17,500 | 98.47 | 1.72M | 17,500 | D | ↗ |
| 2026-02-10 | Smith Hunter C | Officer | S-Sale | D | Common Stock | 1,913 | 102.66 | 196.4K | 123,624 | D | ↗ |
| 2026-02-05 | Smith Hunter C | Officer | S-Sale | D | Common Stock | 3,381 | 106.06 | 358.6K | 125,537 | D | ↗ |
| 2026-02-04 | Smith Hunter C | Officer | S-Sale | D | Common Stock | 1,500 | 104.74 | 157.1K | 130,665 | D | ↗ |
| 2026-02-01 | Smith Hunter C | Officer | M-Exempt | A | Common Stock | 26,000 | 0.00 | — | 142,915 | D | ↗ |
| 2026-02-01 | Shulman Joseph | Officer | M-Exempt | D | Restricted Stock Units | 3,937 | 0.00 | — | 3,937 | D | ↗ |
| 2026-02-01 | Meeker David P | Director / Officer | M-Exempt | D | Restricted Stock Units | 14,125 | 0.00 | — | 14,125 | D | ↗ |
| 2026-02-01 | Mazabraud Yann | Officer | M-Exempt | A | Common Stock | 5,500 | 0.00 | — | 43,155 | D | ↗ |
| 2026-02-01 | Lee Jennifer Kayden | Officer | F-InKind | D | Common Stock | 9,237 | 108.99 | 1.01M | 19,233 | D | ↗ |
| 2026-02-01 | German Christopher Paul | Officer | M-Exempt | D | Restricted Stock Units | 1,807 | 0.00 | — | 5,418 | D | ↗ |
| 2026-02-01 | Garfield Alastair | Officer | M-Exempt | D | Restricted Stock Units | 6,663 | 0.00 | — | 19,987 | D | ↗ |
| 2026-02-01 | Cramer Pamela J. | Officer | M-Exempt | D | Restricted Stock Units | 2,343 | 0.00 | — | 0 | D | ↗ |
| 2025-12-11 | Cramer Pamela J. | Officer | M-Exempt | D | Stock Options (Right to Buy) | 3,350 | 27.35 | 91.6K | 8,375 | D | ↗ |
| 2025-11-20 | Cramer Pamela J. | Officer | M-Exempt | A | Common Stock | 3,350 | 27.35 | 91.6K | 24,164 | D | ↗ |
| 2025-11-10 | Cramer Pamela J. | Officer | M-Exempt | D | Stock Options (Right to Buy) | 3,515 | 6.80 | 23.9K | 3,520 | D | ↗ |
| 2025-11-07 | Cramer Pamela J. | Officer | S-Sale | D | Common Stock | 19,351 | 98.82 | 1.91M | 20,814 | D | ↗ |
| 2025-10-30 | Shulman Joseph | Officer | M-Exempt | A | Common Stock | 9,748 | 30.66 | 298.9K | 18,257 | D | ↗ |
| 2025-10-28 | Shulman Joseph | Officer | M-Exempt | D | Stock Options (Right to Buy) | 2,094 | 27.35 | 57.3K | 12,563 | D | ↗ |
| 2025-10-16 | Shulman Joseph | Officer | S-Sale | D | Common Stock | 8,332 | 112.06 | 933.6K | 11,921 | D | ↗ |
| 2025-09-02 | Shulman Joseph | Officer | M-Exempt | A | Common Stock | 14,687 | 30.66 | 450.3K | 25,290 | D | ↗ |
| 2025-08-21 | Shulman Joseph | Officer | M-Exempt | A | Common Stock | 4,188 | 27.35 | 114.5K | 12,697 | D | ↗ |
| 2025-08-13 | Smith Hunter C | Officer | M-Exempt | A | Common Stock | 3,477 | 6.88 | 23.9K | 120,392 | D | ↗ |
| 2025-08-12 | Smith Hunter C | Officer | M-Exempt | D | Stock Options (Right to Buy) | 24,611 | 6.88 | 169.3K | 3,477 | D | ↗ |
| 2025-08-12 | German Christopher Paul | Officer | M-Exempt | D | Stock Options (Right to Buy) | 500 | 49.23 | 24.6K | 4,050 | D | ↗ |
| 2025-08-11 | Shulman Joseph | Officer | M-Exempt | A | Common Stock | 3,984 | 6.80 | 27.1K | 12,493 | D | ↗ |
| 2025-07-29 | Cramer Pamela J. | Officer | S-Sale | D | Common Stock | 1,520 | 85.93 | 130.6K | 20,814 | D | ↗ |
| 2025-07-26 | Cramer Pamela J. | Officer | M-Exempt | A | Common Stock | 3,125 | 0.00 | — | 22,334 | D | ↗ |
| 2025-07-09 | Smith Hunter C | Officer | M-Exempt | D | Stock Options (Right to Buy) | 42,120 | 6.88 | 289.8K | 28,088 | D | ↗ |
| 2025-07-09 | Shulman Joseph | Officer | S-Sale | D | Common Stock | 3,984 | 75.56 | 301.1K | 12,494 | D | ↗ |
| 2025-07-09 | German Christopher Paul | Officer | M-Exempt | A | Common Stock | 2,000 | 17.97 | 35.9K | 3,889 | D | ↗ |
| 2025-07-09 | Cramer Pamela J. | Officer | S-Sale | D | Common Stock | 4,225 | 75.55 | 319.2K | 30,556 | D | ↗ |
| 2025-07-07 | Smith Hunter C | Officer | M-Exempt | A | Common Stock | 6,986 | 6.88 | 48.1K | 116,915 | D | ↗ |
| 2025-07-02 | Garfield Alastair | Officer | S-Sale | D | Common Stock | 1,313 | 64.81 | 85.1K | 3,132 | D | ↗ |
| 2025-07-01 | Garfield Alastair | Officer | M-Exempt | A | Common Stock | 4,445 | 0.00 | — | 4,445 | D | ↗ |
| 2025-06-24 | TETRAULT LYNN A. | Director | A-Award | A | Restricted Stock Units | 4,712 | 0.00 | — | 4,712 | D | ↗ |
| 2025-06-24 | Mathers Edward T | Director | A-Award | A | Restricted Stock Units | 4,712 | 0.00 | — | 4,712 | D | ↗ |
| 2025-06-24 | MCGIRR DAVID W J | Director | A-Award | A | Restricted Stock Units | 4,712 | 0.00 | — | 4,712 | D | ↗ |
| 2025-06-24 | JEAN CHRISTOPHE | Director | A-Award | A | Stock Option (right to buy) | 7,037 | 63.66 | 448.0K | 7,037 | D | ↗ |
| 2025-06-24 | GOOD JENNIFER L | Director | A-Award | A | Restricted Stock Units | 4,712 | 0.00 | — | 4,712 | D | ↗ |
| 2025-06-24 | Bedrosian Camille L | Director | A-Award | A | Restricted Stock Units | 4,712 | 0.00 | — | 4,712 | D | ↗ |
| 2025-06-24 | Arbuckle Stuart A | Director | A-Award | A | Restricted Stock Units | 4,712 | 0.00 | — | 4,712 | D | ↗ |
| 2025-06-18 | TETRAULT LYNN A. | Director | M-Exempt | A | Common Stock | 4,000 | 0.00 | — | 7,000 | D | ↗ |
| 2025-06-18 | Mathers Edward T | Director | M-Exempt | D | Restricted Stock Units | 4,000 | 0.00 | — | 0 | D | ↗ |
| 2025-06-18 | MCGIRR DAVID W J | Director | M-Exempt | D | Restricted Stock Units | 4,000 | 0.00 | — | 0 | D | ↗ |
| 2025-06-18 | JEAN CHRISTOPHE | Director | M-Exempt | D | Restricted Stock Units | 4,000 | 0.00 | — | 0 | D | ↗ |
| 2025-06-18 | GOOD JENNIFER L | Director | M-Exempt | D | Restricted Stock Units | 4,000 | 0.00 | — | 0 | D | ↗ |
| 2025-06-18 | Bedrosian Camille L | Director | M-Exempt | A | Common Stock | 4,000 | 0.00 | — | 7,000 | D | ↗ |
| 2025-06-18 | Arbuckle Stuart A | Director | M-Exempt | D | Restricted Stock Units | 4,000 | 0.00 | — | 0 | D | ↗ |
| 2025-06-10 | German Christopher Paul | Officer | S-Sale | D | Common Stock | 2,069 | 67.19 | 139.0K | 1,889 | D | ↗ |
| 2025-06-06 | Cramer Pamela J. | Officer | M-Exempt | D | Stock Options (Right to Buy) | 7,031 | 6.80 | 47.8K | 28,128 | D | ↗ |
| 2025-06-03 | Meeker David P | Director / Officer | S-Sale | D | Common Stock | 274 | 65.60 | 18.0K | 201,825 | D | ↗ |
| 2025-06-03 | MCGIRR DAVID W J | Director | M-Exempt | A | Common Stock | 65,431 | 4.59 | 300.3K | 68,431 | D | ↗ |
| 2025-05-30 | Smith Hunter C | Officer | S-Sale | D | Common Stock | 4,407 | 60.93 | 268.5K | 128,922 | D | ↗ |
| 2025-04-29 | Mazabraud Yann | Officer | S-Sale | D | Common Stock | 6,745 | 65.08 | 438.9K | 37,655 | D | ↗ |
| 2025-04-29 | Cramer Pamela J. | Officer | M-Exempt | D | Stock Options (Right to Buy) | 7,031 | 6.80 | 47.8K | 35,159 | D | ↗ |
| 2025-04-15 | Mazabraud Yann | Officer | M-Exempt | D | Restricted Stock Units | 2,500 | 0.00 | — | 7,500 | D | ↗ |
| 2025-04-14 | Mazabraud Yann | Officer | M-Exempt | D | Restricted Stock Units | 10,375 | 0.00 | — | 20,750 | D | ↗ |
| 2025-04-08 | Mazabraud Yann | Officer | S-Sale | D | Common Stock | 9,312 | 61.54 | 573.1K | 22,620 | D | ↗ |
| 2025-04-08 | Cramer Pamela J. | Officer | S-Sale | D | Common Stock | 600 | 59.00 | 35.4K | 32,939 | D | ↗ |
| 2025-03-21 | German Christopher Paul | Officer | S-Sale | D | Common Stock | 344 | 54.23 | 18.7K | 2,889 | D | ↗ |
| 2025-03-20 | German Christopher Paul | Officer | M-Exempt | A | Common Stock | 1,163 | 0.00 | — | 3,233 | D | ↗ |
| 2025-03-14 | Mazabraud Yann | Officer | M-Exempt | A | Common Stock | 75,000 | 22.28 | 1.67M | 115,370 | D | ↗ |
| 2025-02-19 | Smith Hunter C | Officer | S-Sale | D | Common Stock | 2,215 | 57.22 | 126.7K | 109,929 | D | ↗ |
| 2025-02-19 | Shulman Joseph | Officer | S-Sale | D | Common Stock | 1,228 | 57.22 | 70.3K | 8,509 | D | ↗ |
| 2025-02-19 | Meeker David P | Director / Officer | S-Sale | D | Common Stock | 9,896 | 57.22 | 566.2K | 201,281 | D | ↗ |
| 2025-02-19 | Lee Jennifer Kayden | Officer | S-Sale | D | Common Stock | 2,035 | 57.22 | 116.4K | 5,858 | D | ↗ |
| 2025-02-19 | German Christopher Paul | Officer | S-Sale | D | Common Stock | 635 | 57.22 | 36.3K | 2,070 | D | ↗ |
| 2025-02-19 | Cramer Pamela J. | Officer | S-Sale | D | Common Stock | 982 | 57.22 | 56.2K | 19,209 | D | ↗ |
| 2025-02-16 | Smith Hunter C | Officer | M-Exempt | D | Restricted Stock Units | 6,600 | 0.00 | — | 19,800 | D | ↗ |
| 2025-02-16 | Shulman Joseph | Officer | M-Exempt | A | Common Stock | 4,125 | 0.00 | — | 9,737 | D | ↗ |
| 2025-02-16 | Meeker David P | Director / Officer | M-Exempt | D | Restricted Stock Units | 21,250 | 0.00 | — | 63,750 | D | ↗ |
| 2025-02-16 | Mazabraud Yann | Officer | M-Exempt | A | Common Stock | 5,500 | 0.00 | — | 40,370 | D | ↗ |
| 2025-02-16 | Lee Jennifer Kayden | Officer | M-Exempt | A | Common Stock | 5,500 | 0.00 | — | 7,893 | D | ↗ |
| 2025-02-16 | German Christopher Paul | Officer | M-Exempt | D | Restricted Stock Units | 1,807 | 0.00 | — | 5,418 | D | ↗ |
| 2025-02-16 | Cramer Pamela J. | Officer | M-Exempt | D | Restricted Stock Units | 3,300 | 0.00 | — | 9,900 | D | ↗ |
| 2025-02-14 | Smith Hunter C | Officer | A-Award | A | Stock Options (Right to Buy) | 62,500 | 56.69 | 3.54M | 62,500 | D | ↗ |
| 2025-02-14 | Shulman Joseph | Officer | A-Award | A | Restricted Stock Units | 25,000 | 0.00 | — | 25,000 | D | ↗ |
| 2025-02-14 | Meeker David P | Director / Officer | A-Award | A | Restricted Stock Units | 133,350 | 0.00 | — | 133,350 | D | ↗ |
| 2025-02-14 | Mazabraud Yann | Officer | A-Award | A | Restricted Stock Units | 40,000 | 0.00 | — | 40,000 | D | ↗ |
| 2025-02-14 | Lee Jennifer Kayden | Officer | A-Award | A | Restricted Stock Units | 36,650 | 0.00 | — | 36,650 | D | ↗ |
| 2025-02-14 | German Christopher Paul | Officer | A-Award | A | Restricted Stock Units | 7,225 | 0.00 | — | 7,225 | D | ↗ |
| 2025-02-14 | Garfield Alastair | Officer | A-Award | A | Stock Options (Right to Buy) | 40,000 | 56.69 | 2.27M | 40,000 | D | ↗ |
| 2025-02-14 | Cramer Pamela J. | Officer | A-Award | A | Restricted Stock Units | 20,000 | 0.00 | — | 20,000 | D | ↗ |
| 2025-02-13 | Lee Jennifer Kayden | Officer | S-Sale | D | Common Stock | 1,205 | 58.00 | 69.9K | 2,393 | D | ↗ |
| 2025-02-12 | Smith Hunter C | Officer | S-Sale | D | Common Stock | 739 | 56.39 | 41.7K | 105,556 | D | ↗ |
| 2025-02-12 | Shulman Joseph | Officer | S-Sale | D | Common Stock | 462 | 56.39 | 26.1K | 5,619 | D | ↗ |
| 2025-02-12 | Lee Jennifer Kayden | Officer | S-Sale | D | Common Stock | 600 | 56.39 | 33.8K | 4,813 | D | ↗ |
| 2025-02-11 | Smith Hunter C | Officer | S-Sale | D | Common Stock | 5 | 57.53 | 287.65 | 106,295 | D | ↗ |
| 2025-02-11 | Shulman Joseph | Officer | M-Exempt | D | Restricted Stock Units | 1,562 | 0.00 | — | 0 | D | ↗ |
| 2025-02-11 | Lee Jennifer Kayden | Officer | M-Exempt | D | Restricted Stock Units | 2,031 | 0.00 | — | 0 | D | ↗ |
| 2025-02-11 | Cramer Pamela J. | Officer | S-Sale | D | Common Stock | 3 | 57.54 | 172.62 | 16,891 | D | ↗ |
| 2025-02-10 | Lee Jennifer Kayden | Officer | S-Sale | D | Common Stock | 1,894 | 58.39 | 110.6K | 6,704 | D | ↗ |
| 2025-02-09 | Smith Hunter C | Officer | M-Exempt | A | Common Stock | 4,062 | 0.00 | — | 105,248 | D | ↗ |
| 2025-02-09 | Shulman Joseph | Officer | M-Exempt | D | Restricted Stock Units | 2,656 | 0.00 | — | 2,656 | D | ↗ |
| 2025-02-09 | Lee Jennifer Kayden | Officer | M-Exempt | A | Common Stock | 3,437 | 0.00 | — | 4,409 | D | ↗ |
| 2025-02-09 | Cramer Pamela J. | Officer | M-Exempt | D | Restricted Stock Units | 2,344 | 0.00 | — | 2,343 | D | ↗ |
| 2025-02-05 | Lee Jennifer Kayden | Officer | S-Sale | D | Common Stock | 200 | 61.95 | 12.4K | 972 | D | ↗ |
| 2025-02-04 | Smith Hunter C | Officer | S-Sale | D | Common Stock | 1,678 | 59.43 | 99.7K | 101,186 | D | ↗ |
| 2025-02-04 | Shulman Joseph | Officer | S-Sale | D | Common Stock | 1,281 | 59.43 | 76.1K | 2,657 | D | ↗ |
| 2025-02-04 | Meeker David P | Director / Officer | S-Sale | D | Common Stock | 4,278 | 59.43 | 254.2K | 189,927 | D | ↗ |
| 2025-02-04 | Lee Jennifer Kayden | Officer | S-Sale | D | Common Stock | 1,447 | 59.43 | 86.0K | 4,038 | D | ↗ |
| 2025-02-04 | Cramer Pamela J. | Officer | S-Sale | D | Common Stock | 902 | 59.43 | 53.6K | 15,248 | D | ↗ |
| 2025-02-01 | Smith Hunter C | Officer | M-Exempt | D | Restricted Stock Units | 4,925 | 0.00 | — | 9,850 | D | ↗ |
| 2025-02-01 | Shulman Joseph | Officer | M-Exempt | A | Common Stock | 3,938 | 0.00 | — | 3,938 | D | ↗ |
| 2025-02-01 | Meeker David P | Director / Officer | M-Exempt | A | Common Stock | 14,125 | 0.00 | — | 194,205 | D | ↗ |
| 2025-02-01 | Lee Jennifer Kayden | Officer | M-Exempt | D | Restricted Stock Units | 4,513 | 0.00 | — | 9,024 | D | ↗ |
| 2025-02-01 | Cramer Pamela J. | Officer | M-Exempt | A | Common Stock | 2,650 | 0.00 | — | 16,150 | D | ↗ |
| 2024-11-11 | Shulman Joseph | Officer | S-Sale | D | Common Stock | 6,604 | 65.73 | 434.1K | 6,677 | D | ↗ |
| 2024-11-11 | Lee Jennifer Kayden | Officer | S-Sale | D | Common Stock | 11,070 | 67.56 | 747.9K | 1,172 | D | ↗ |
| 2024-11-07 | Cramer Pamela J. | Officer | M-Exempt | A | Common Stock | 4,688 | 19.02 | 89.2K | 18,188 | D | ↗ |
| 2024-11-06 | Cramer Pamela J. | Officer | S-Sale | D | Common Stock | 4,687 | 60.00 | 281.2K | 13,500 | D | ↗ |
| 2024-09-17 | GOOD JENNIFER L | Director | M-Exempt | D | Stock Option (right to buy) | 7,501 | 18.99 | 142.4K | 0 | — | ↗ |
| 2024-09-10 | TETRAULT LYNN A. | Director | M-Exempt | D | Stock Option (right to buy) | 7,501 | 18.99 | 142.4K | 0 | — | ↗ |
| 2024-09-09 | TETRAULT LYNN A. | Director | M-Exempt | A | Common Stock | 3,199 | 18.99 | 60.7K | 6,199 | — | ↗ |
| 2024-09-09 | GOOD JENNIFER L | Director | M-Exempt | D | Stock Option (right to buy) | 12,900 | 22.93 | 295.8K | 15,000 | — | ↗ |
| 2024-09-09 | Cramer Pamela J. | Officer | S-Sale | D | Common Stock | 4,099 | 50.03 | 205.1K | 13,500 | — | ↗ |
| 2024-08-26 | TETRAULT LYNN A. | Director | S-Sale | D | Common Stock | 4,300 | 50.01 | 215.0K | 3,000 | — | ↗ |
| 2024-08-26 | GOOD JENNIFER L | Director | S-Sale | D | Common Stock | 14,508 | 50.01 | 725.5K | 3,000 | — | ↗ |
| 2024-08-26 | Cramer Pamela J. | Officer | S-Sale | D | Common Stock | 3,200 | 50.01 | 160.0K | 13,500 | — | ↗ |
| 2024-08-12 | TETRAULT LYNN A. | Director | S-Sale | D | Common Stock | 9,593 | 44.62 | 428.0K | 3,407 | — | ↗ |
| 2024-08-09 | Cramer Pamela J. | Officer | S-Sale | D | Common Stock | 2,104 | 45.62 | 96.0K | 13,500 | — | ↗ |
| 2024-07-29 | Cramer Pamela J. | Officer | S-Sale | D | Common Stock | 1,395 | 49.06 | 68.4K | 31,735 | — | ↗ |
| 2024-07-26 | Cramer Pamela J. | Officer | M-Exempt | A | Common Stock | 3,125 | 0.00 | — | 33,130 | — | ↗ |
| 2024-07-16 | Shulman Joseph | Officer | S-Sale | D | Common Stock | 10,468 | 53.00 | 554.8K | 30 | — | ↗ |
| 2024-07-12 | Shulman Joseph | Officer | M-Exempt | A | Common Stock | 5,313 | 21.38 | 113.6K | 5,343 | — | ↗ |
| 2024-07-08 | Garfield Alastair | Officer | A-Award | A | Restricted Stock Units | 17,778 | 0.00 | — | 17,778 | — | ↗ |
| 2024-06-21 | TETRAULT LYNN A. | Director | M-Exempt | D | Restricted Stock Units | 3,000 | 0.00 | — | 0 | — | ↗ |
| 2024-06-21 | Mathers Edward T | Director | M-Exempt | A | Common Stock | 3,000 | 0.00 | — | 3,000 | — | ↗ |
| 2024-06-21 | MCGIRR DAVID W J | Director | M-Exempt | D | Restricted Stock Units | 3,000 | 0.00 | — | 0 | — | ↗ |
| 2024-06-21 | JEAN CHRISTOPHE | Director | M-Exempt | A | Common Stock | 3,000 | 0.00 | — | 3,000 | — | ↗ |
| 2024-06-21 | GOOD JENNIFER L | Director | M-Exempt | A | Common Stock | 3,000 | 0.00 | — | 3,000 | — | ↗ |
| 2024-06-21 | Bedrosian Camille L | Director | M-Exempt | A | Common Stock | 3,000 | 0.00 | — | 3,000 | — | ↗ |
| 2024-06-21 | Arbuckle Stuart A | Director | M-Exempt | A | Common Stock | 3,000 | 0.00 | — | 3,000 | — | ↗ |
| 2024-06-18 | TETRAULT LYNN A. | Director | A-Award | A | Restricted Stock Units | 4,000 | 0.00 | — | 4,000 | — | ↗ |
| 2024-06-18 | Mathers Edward T | Director | A-Award | A | Stock Option (right to buy) | 14,000 | 41.39 | 579.5K | 14,000 | — | ↗ |
| 2024-06-18 | MCGIRR DAVID W J | Director | A-Award | A | Restricted Stock Units | 4,000 | 0.00 | — | 4,000 | — | ↗ |
| 2024-06-18 | JEAN CHRISTOPHE | Director | A-Award | A | Restricted Stock Units | 4,000 | 0.00 | — | 4,000 | — | ↗ |
| 2024-06-18 | GOOD JENNIFER L | Director | A-Award | A | Stock Option (right to buy) | 14,000 | 41.39 | 579.5K | 14,000 | — | ↗ |
| 2024-06-18 | Bedrosian Camille L | Director | A-Award | A | Restricted Stock Units | 4,000 | 0.00 | — | 4,000 | — | ↗ |
| 2024-06-18 | Arbuckle Stuart A | Director | A-Award | A | Stock Option (right to buy) | 14,000 | 41.39 | 579.5K | 14,000 | — | ↗ |
| 2024-05-09 | Shulman Joseph | Officer | S-Sale | D | Common Stock | 3,484 | 38.38 | 133.7K | 530 | — | ↗ |
| 2024-04-15 | Mazabraud Yann | Officer | A-Award | A | Restricted Stock Units | 10,000 | 0.00 | — | 10,000 | — | ↗ |
| 2024-04-14 | Mazabraud Yann | Officer | M-Exempt | D | Common Stock | 10,375 | 0.00 | — | 34,870 | — | ↗ |
| 2024-04-02 | German Christopher Paul | Officer | S-Sale | D | Common Stock | 368 | 41.76 | 15.4K | 795 | — | ↗ |
| 2024-03-21 | Shulman Joseph | Officer | S-Sale | D | Common Stock | 18,235 | 40.34 | 735.6K | 30 | — | ↗ |
| 2024-03-20 | Lee Jennifer Kayden | Officer | S-Sale | D | Common Stock | 9,169 | 38.22 | 350.4K | 15,918 | — | ↗ |
| 2024-03-20 | German Christopher Paul | Officer | M-Exempt | D | Restricted Stock Units | 1,163 | 0.00 | — | 3,487 | — | ↗ |
| 2024-03-19 | Smith Hunter C | Officer | S-Sale | D | Common Stock | 15,515 | 39.22 | 608.5K | 97,939 | — | ↗ |
| 2024-03-19 | Shulman Joseph | Officer | S-Sale | D | Common Stock | 15,515 | 39.22 | 608.5K | 18,265 | — | ↗ |
| 2024-03-19 | Meeker David P | Director / Officer | S-Sale | D | Common Stock | 45,494 | 39.22 | 1.78M | 174,605 | — | ↗ |
| 2024-03-19 | Mazabraud Yann | Officer | S-Sale | D | Common Stock | 16,000 | 39.22 | 627.5K | 24,495 | — | ↗ |
| 2024-03-19 | Lee Jennifer Kayden | Officer | S-Sale | D | Common Stock | 15,515 | 39.22 | 608.5K | 25,087 | — | ↗ |
| 2024-03-19 | Cramer Pamela J. | Officer | S-Sale | D | Common Stock | 15,515 | 39.22 | 608.5K | 30,005 | — | ↗ |
| 2024-02-16 | Smith Hunter C | Officer | A-Award | A | Restricted Stock Units | 26,400 | 0.00 | — | 26,400 | — | ↗ |
| 2024-02-16 | Shulman Joseph | Officer | A-Award | A | Common Stock | 33,750 | 0.00 | — | 33,780 | — | ↗ |
| 2024-02-16 | Meeker David P | Director / Officer | A-Award | A | Restricted Stock Units | 85,000 | 0.00 | — | 85,000 | — | ↗ |
| 2024-02-16 | Mazabraud Yann | Officer | A-Award | A | Stock Option (Right to Buy) | 67,000 | 49.23 | 3.30M | 67,000 | — | ↗ |
| 2024-02-16 | Lee Jennifer Kayden | Officer | A-Award | A | Stock Option (Right to Buy) | 67,000 | 49.23 | 3.30M | 67,000 | — | ↗ |
| 2024-02-16 | German Christopher Paul | Officer | A-Award | A | Restricted Stock Units | 7,225 | 0.00 | — | 7,225 | — | ↗ |
| 2024-02-14 | Shulman Joseph | Officer | S-Sale | D | Common Stock | 1,089 | 50.01 | 54.5K | 30 | — | ↗ |
| 2024-02-13 | Smith Hunter C | Officer | S-Sale | D | Common Stock | 709 | 49.82 | 35.3K | 79,704 | — | ↗ |
| 2024-02-13 | Shulman Joseph | Officer | S-Sale | D | Common Stock | 473 | 49.84 | 23.6K | 2,984 | — | ↗ |
| 2024-02-13 | Mazabraud Yann | Officer | S-Sale | D | Common Stock | 957 | 49.84 | 47.7K | 6,745 | — | ↗ |
| 2024-02-13 | Lee Jennifer Kayden | Officer | S-Sale | D | Common Stock | 615 | 49.83 | 30.6K | 6,852 | — | ↗ |
| 2024-02-12 | Smith Hunter C | Officer | S-Sale | D | Common Stock | 1,209 | 51.38 | 62.1K | 80,413 | — | ↗ |
| 2024-02-12 | Shulman Joseph | Officer | S-Sale | D | Common Stock | 791 | 51.38 | 40.6K | 3,457 | — | ↗ |
| 2024-02-12 | Mazabraud Yann | Officer | S-Sale | D | Common Stock | 1,594 | 51.38 | 81.9K | 7,702 | — | ↗ |
| 2024-02-12 | Lee Jennifer Kayden | Officer | S-Sale | D | Common Stock | 1,023 | 51.38 | 52.6K | 7,467 | — | ↗ |
| 2024-02-12 | Cramer Pamela J. | Officer | S-Sale | D | Common Stock | 696 | 51.38 | 35.8K | 11,770 | — | ↗ |
| 2024-02-11 | Smith Hunter C | Officer | M-Exempt | A | Common Stock | 2,344 | 0.00 | — | 81,622 | — | ↗ |
| 2024-02-11 | Shulman Joseph | Officer | M-Exempt | A | Common Stock | 1,562 | 0.00 | — | 4,248 | — | ↗ |
| 2024-02-11 | Mazabraud Yann | Officer | M-Exempt | A | Common Stock | 2,031 | 0.00 | — | 9,296 | — | ↗ |
| 2024-02-11 | Lee Jennifer Kayden | Officer | M-Exempt | D | Restricted Stock Units | 2,031 | 0.00 | — | 2,031 | — | ↗ |
| 2024-02-09 | Smith Hunter C | Officer | M-Exempt | D | Restricted Stock Units | 4,063 | 0.00 | — | 8,124 | — | ↗ |
| 2024-02-09 | Shulman Joseph | Officer | M-Exempt | A | Common Stock | 2,656 | 0.00 | — | 5,270 | — | ↗ |
| 2024-02-09 | Mazabraud Yann | Officer | M-Exempt | A | Common Stock | 3,438 | 0.00 | — | 7,265 | — | ↗ |
| 2024-02-09 | Lee Jennifer Kayden | Officer | M-Exempt | D | Restricted Stock Units | 3,438 | 0.00 | — | 6,874 | — | ↗ |
| 2024-02-09 | Cramer Pamela J. | Officer | M-Exempt | D | Restricted Stock Units | 2,344 | 0.00 | — | 4,687 | — | ↗ |
| 2024-02-01 | Smith Hunter C | Officer | S-Sale | D | Common Stock | 1,616 | 45.06 | 72.8K | 75,215 | — | ↗ |
| 2024-02-01 | Shulman Joseph | Officer | M-Exempt | A | Common Stock | 3,938 | 0.00 | — | 3,938 | — | ↗ |
| 2024-02-01 | Meeker David P | Director / Officer | M-Exempt | D | Restricted Stock Units | 14,125 | 0.00 | — | 42,375 | — | ↗ |
Executive team
Top executives
EBIT / Employee
-620.0K
Shares Outstanding
68.29M
Executive compensation
Executive compensation (annual)
| # | Year | Executive | Salary | Bonus | Stock award | Option award | Incentive | Other | Total | % Stock- based |
Filing |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 2025 | David P. Meeker Chief Executive Officer | 807.7K | — | 8.27M | 7.69M | 759.5K | 14.0K | 17.54M | 90.99% | ↗ |
| 2 | 2025 | Hunter C. Smith Chief Financial Officer | 540.5K | — | 2.93M | 2.40M | 338.0K | 14.0K | 6.23M | 85.67% | ↗ |
| 3 | 2025 | Yann Mazabraud Executive Vice President, Head of International | 557.2K | — | 2.84M | 2.31M | 344.7K | 70.3K | 6.12M | 84.11% | ↗ |
| 4 | 2025 | Jennifer Lee Executive Vice President, Head of North America | 531.6K | — | 2.65M | 2.11M | 293.0K | 14.0K | 5.60M | 85.03% | ↗ |
| 5 | 2025 | Alastair Garfield Chief Scientific Officer | 505.4K | — | 2.08M | 1.54M | 287.0K | 14.0K | 4.43M | 81.78% | ↗ |
| 6 | 2024 | David P. Meeker Chief Executive Officer | 740.5K | — | 4.38M | 8.78M | 744.1K | 12.1K | 14.66M | 89.79% | ↗ |
| 7 | 2024 | Yann Mazabraud Executive Vice President, Head of International | 467.2K | — | 2.00M | 2.27M | 297.1K | 58.9K | 5.10M | 83.84% | ↗ |
| 8 | 2024 | Hunter C. Smith Chief Financial Officer | 499.4K | — | 1.46M | 2.73M | 352.0K | 13.8K | 5.05M | 82.87% | ↗ |
| 9 | 2024 | Jennifer Lee Executive Vice President, Head of North America | 488.3K | — | 1.24M | 2.27M | 302.0K | 13.8K | 4.32M | 81.38% | ↗ |
| 10 | 2024 | Joseph Shulman Chief Technical Officer | 449.1K | — | 971.0K | 1.70M | 272.0K | 13.8K | 3.41M | 78.45% | ↗ |
| 11 | 2023 | David P. Meeker Chief Executive Officer | 704.7K | — | 1.55M | 4.33M | 634.1K | 11.9K | 7.23M | 81.32% | ↗ |
| 12 | 2023 | Hunter C. Smith Chief Financial Officer | 476.2K | — | 538.8K | 1.01M | 261.0K | 20.2K | 2.31M | 67.19% | ↗ |
| 13 | 2023 | Jennifer Lee Executive Vice President, Head of North America | 464.7K | — | 493.7K | 885.4K | 246.0K | 16.4K | 2.11M | 65.48% | ↗ |
| 14 | 2023 | Joseph Shulman Chief Technical Officer | 430.2K | — | 430.8K | 632.4K | 226.0K | 21.1K | 1.74M | 61.09% | ↗ |
| 15 | 2023 | Yann Mazabraud Executive Vice President, Head of International | 448.8K | — | 805.1K | — | 238.7K | 51.6K | 1.54M | 52.14% | ↗ |
| 16 | 2022 | David P. Meeker Chief Executive Officer | 652.1K | — | — | 2.16M | 505.4K | 11.0K | 3.33M | 64.87% | ↗ |
| 17 | 2022 | Hunter C. Smith Chief Financial Officer | 460.0K | — | 110.5K | 412.4K | 217.0K | 15.2K | 1.22M | 43.03% | ↗ |
| 18 | 2022 | Yann Mazabraud Executive Vice President, Head of International | 380.6K | — | 93.5K | 349.0K | 202.7K | 164.1K | 1.19M | 37.19% | ↗ |
| 19 | 2022 | Jennifer Lee Executive Vice President, Head of North America | 430.0K | — | 93.5K | 349.0K | 202.0K | 12.2K | 1.09M | 40.72% | ↗ |
| 20 | 2022 | Jennifer Chien Executive Vice President, Head of North America | 430.0K | — | 93.5K | 349.0K | 202.0K | 12.2K | 1.09M | 40.72% | ↗ |
| 21 | 2022 | Joseph Shulman Chief Technical Officer | 410.0K | — | 72.3K | 269.7K | 186.0K | 12.2K | 950.1K | 35.99% | ↗ |
| 22 | 2021 | David P. Meeker Chief Executive Officer | 630.0K | — | 1.16M | 4.20M | 451.0K | 8.4K | 6.46M | 83.13% | ↗ |
| 23 | 2021 | Hunter C. Smith Chief Financial Officer | 436.0K | — | 576.3K | 1.07M | 210.7K | 11.6K | 2.31M | 71.50% | ↗ |
| 24 | 2021 | Yann Mazabraud Executive Vice President, Head of International | 384.3K | — | 552.4K | 931.6K | 190.9K | 118.5K | 2.18M | 68.15% | ↗ |
| 25 | 2021 | Jennifer Lee Executive Vice President, Head of North America | 395.0K | — | 552.4K | 931.6K | 190.9K | 11.6K | 2.08M | 71.30% | ↗ |
| 26 | 2021 | Jennifer Chien Executive Vice President, Head of North America | 395.0K | — | 552.4K | 931.6K | 190.9K | 11.6K | 2.08M | 71.30% | ↗ |
| 27 | 2021 | Murray Stewart Former Chief Medical Officer | 365.8K | — | 320.5K | 1.07M | 187.9K | 5.00 | 1.99M | 70.10% | ↗ |
| 28 | 2021 | Joseph Shulman Chief Technical Officer | 386.3K | — | 516.5K | 716.6K | 157.2K | 11.6K | 1.79M | 68.96% | ↗ |
| 29 | 2020 | David P. Meeker Chief Executive Officer | 262.3K | — | 918.5K | 12.84M | 208.0K | 43.7K | 14.28M | 96.40% | ↗ |
| 30 | 2020 | David P. Meeker, M.D. President and Chief Executive Officer | 262.3K | — | 918.5K | 12.84M | 208.0K | 43.7K | 13.36M | 103.03% | ↗ |
| 31 | 2020 | Keith M. Gottesdiener, M.D. Former President and Chief Executive Officer | 142.9K | — | — | 2.81M | — | 495.5K | 3.45M | 81.49% | ↗ |
| 32 | 2020 | Hunter C. Smith Chief Financial Officer | 416.1K | 60.0K | 132.0K | 1.84M | 209.6K | 7.1K | 2.66M | 73.98% | ↗ |
| 33 | 2020 | Hunter C. Smith Chief Financial Officer, Treasurer, Secretary and Former Interim President and Chief Executive Officer | 416.1K | 60.0K | 132.0K | 1.84M | 209.6K | 7.1K | 2.53M | 77.84% | ↗ |
| 34 | 2020 | Murray Stewart Former Chief Medical Officer | 451.2K | 60.0K | 113.0K | 1.56M | 226.6K | 7.1K | 2.30M | 72.53% | ↗ |
| 35 | 2020 | Murray Stewart, D.M., F.R.C.P. Chief Medical Officer | 451.2K | 60.0K | 113.0K | 1.56M | 226.6K | 7.1K | 2.30M | 72.53% | ↗ |
| 36 | 2020 | Nithya Desikan Former Chief Commercial Officer | 305.5K | — | 105.0K | 1.53M | — | 104.6K | 1.94M | 84.30% | ↗ |
| 37 | 2020 | Jennifer Chien Executive Vice President, Head of North America | 45.6K | 100.0K | 100.0K | 1.52M | 49.4K | 7.1K | 1.82M | 88.89% | ↗ |
| 38 | 2019 | Keith M. Gottesdiener, M.D., Former President and Chief Executive Officer | 525.9K | — | — | 4.13M | 277.3K | — | 4.94M | 83.73% | ↗ |
| 39 | 2019 | Keith M. Gottesdiener, M.D. Former President and Chief Executive Officer | 525.9K | — | — | 4.13M | 277.3K | — | 4.94M | 83.73% | ↗ |
| 40 | 2019 | Hunter C. Smith Chief Financial Officer | 394.0K | — | — | 1.29M | 153.2K | 86.6K | 1.92M | 66.88% | ↗ |
| 41 | 2019 | Hunter C. Smith Chief Financial Officer, Treasurer, Secretary and Former Interim President and Chief Executive Officer | 397.0K | — | — | 1.29M | 153.2K | 86.6K | 1.92M | 66.88% | ↗ |
| 42 | 2019 | Hunter C. Smith, Chief Financial Officer, Treasurer, Secretary and Interim President and Chief Executive Officer | 397.0K | — | — | 1.29M | 153.2K | 86.6K | 1.92M | 66.88% | ↗ |
| 43 | 2019 | Nithya Desikan Chief Commercial Officer | 379.1K | — | — | 1.29M | 145.1K | — | 1.81M | 71.04% | ↗ |
| 44 | 2019 | Nithya Desikan Former Chief Commercial Officer | 379.1K | — | — | 1.29M | 145.1K | — | 1.81M | 71.04% | ↗ |
| 45 | 2018 | Keith M. Gottesdiener, M.D., President and Chief Executive Officer, Director | 505.5K | — | — | 2.76M | 278.0K | — | 3.54M | 77.86% | ↗ |
| 46 | 2018 | Keith M. Gottesdiener, M.D., Former President and Chief Executive Officer | 505.5K | — | — | 2.76M | 278.0K | — | 3.54M | 77.86% | ↗ |
| 47 | 2018 | Hunter C. Smith, Chief Financial Officer, Treasurer, Secretary and Interim President and Chief Executive Officer | 387.6K | — | — | 960.8K | 152.2K | 86.6K | 1.59M | 60.53% | ↗ |
| 48 | 2018 | Hunter C. Smith, Chief Financial Officer | 387.6K | — | — | 960.8K | 152.2K | 86.6K | 1.59M | 60.53% | ↗ |
| 49 | 2018 | Lex H.T. Van der Ploeg, Ph.D., Chief Scientific Officer | 383.4K | — | — | 866.3K | 147.6K | — | 1.40M | 62.00% | ↗ |
| 50 | 2017 | Keith M. Gottesdiener, M.D., President and Chief Executive Officer, Director | 490.8K | — | — | 800.0K | 245.4K | — | 1.54M | 52.08% | ↗ |
| 51 | 2017 | Nithya Desikan, Chief Commercial Officer | 158.1K | 100.0K | — | 832.5K | 66.8K | — | 1.16M | 71.93% | ↗ |
| 52 | 2017 | Hunter C. Smith, Chief Financial Officer | 159.8K | — | — | 832.5K | 70.5K | 27.5K | 1.09M | 76.36% | ↗ |
| 53 | 2016 | Keith M. Gottesdiener, M.D., President and Chief Executive Officer, Director | 476.5K | — | — | — | 85.8K | — | 562.3K | 0.00% | ↗ |
CEO compensation breakdown
Proxy statements
Recent SEC filings
Executive team
| Name | Title | Compensation | Gender |
|---|---|---|---|
| David Meeker | Chairman, President & Chief Executive Officer | 2M | — |
| Yann Mazabraud | Executive Vice President & Head of International | 972.1K | male |
| Hunter C. Smith | Chief Financial Officer & Treasurer | 892.5K | male |
| Jennifer Lee | Executive Vice President & Head of North America | 838.6K | female |
| Alastair Garfield | Chief Scientific Officer | 806.4K | — |
| Joseph Shulman | Chief Technical Officer | 734.9K | male |
| Jim Flaherty | Senior Vice President & General Counsel | — | male |
| Pamela J. Cramer | Chief Human Resources Officer | — | female |
| Sarah Ryan | Vice President of Sales & Marketing | — | female |
| Elisabeth Cronert-Bendell | Senior Vice President & Head of Strategy | — | — |
| Christopher German | Corporate Controller & Principal Accounting Officer | — | male |
| David Connolly | Head of Investor Relations & Corporate Communications | — | male |
ESG Rating
ESG Score History BIOTECHNOLOGY
Benchmark vs Sector
Senate Trading Activity
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House Trading Activity
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Market share among peers
Peer comparison — filtered group (TTM)
Your opinion
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Community Opinion for RYTM
Short-term intention
Target Price Distribution
These are community opinions and do not constitute buy or sell advice to act on. The results shown are based on aggregated opinions and are not an investment recommendation, nor do they intend to influence any investment decision.
