TransCode Therapeutics, Inc. (RNAZ)
Boston, MA, US
TransCode Therapeutics, Inc. is a biopharmaceutical firm dedicated to pioneering and marketing therapeutic agents and diagnostic tools specifically aimed at combating and detecting metastatic disease. Central to its pipeline is TTX-MC138, a lead therapeutic compound currently undergoing preclinical evaluation for its potential in treating advanced, spreading cancers. Beyond its primary candidate, the company's preclinical portfolio also features TTX-siPDL1, an siRNA designed to modulate programmed death-ligand 1, and TTX-siLIN28B, another siRNA that inhibits the RNA-binding protein LIN28B. TransCode also pursues several cancer-agnostic initiatives. These encompass TTX-RIGA, an RNA-based agent engineered to stimulate the RIG-I immune pathway within the tumor's immediate surroundings; TTX-CRISPR, a gene-editing platform utilizing CRISPR/Cas9 technology to correct or eradicate oncogenic genes within cancer cells; and TTX-mRNA, an innovative mRNA platform dedicated to creating cancer vaccines that incite powerful cytotoxic immune reactions against malignant cells. Established in 2016, TransCode Therapeutics is headquartered in Boston, Massachusetts.
No mergers or acquisitions recorded for this company.
| Indicator | 1D | 1W | 2W | 3W | 1M |
|---|
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
| 1D | 5D | 1M | 3M | 6M | YTD | 1Y | 3Y | 5Y | 10Y | Max |
|---|---|---|---|---|---|---|---|---|---|---|
| -2.78% | -7.30% | -25.00% | -23.79% | -29.86% | -3.37% | -1.49% | -100.00% | -100.00% | -100.00% | -100.00% |
Revenue flow
Revenue by geography
Revenue by segment
Revenue composition
By product
By geography
Income Statement
Balance Sheet
Cash Flow Statement
Key Metrics
Financial Ratios
Employees
Financial Growth (CAGR)
Market Data
DCF figures are point estimates: small changes in growth or discount-rate assumptions move them materially. Read them as a reference, not a precise target.
| Rating | 2025-07 | Change |
|---|---|---|
| Strong Buy | 1 | 0 |
| Buy | 0 | 0 |
| Hold | 0 | 0 |
| Sell | 0 | 0 |
| Strong Sell | 0 | 0 |
-
Revenue growth Biotechnology: +1.6%—
-
EPS growth Biotechnology: +29.7%-11.6% Q1'26: -30,174.6% (vs Q1'25)
-
FCF margin FCF growth · Biotechnology: +16.2%—
-
EBIT margin Biotechnology: +0.0%—
-
ROIC Biotechnology: -16.1%— Q1'26: +0.2% (vs Q1'25)
-
Share dilution Biotechnology: -3.4%+93.7% Q1'26: +432.3% (vs Q1'25)
-
Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×0.00× Q1'26: 0.00× (vs Q1'25)
* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.
| Metric |
Dec 2024 actual |
Dec 2025 actual |
Dec 2026 1 Rev. Ana. 1 EPS Ana. |
Dec 2027 1 Rev. Ana. 1 EPS Ana. |
Dec 2028 1 Rev. Ana. 1 EPS Ana. |
Dec 2029 1 Rev. Ana. 1 EPS Ana. |
|---|---|---|---|---|---|---|
| Revenue |
—
est: 300.0K (-100.0%)
|
—
est: 1.00M (-100.0%)
|
500.0K
500.0K – 500.0K
-50.0% YoY
|
9.70M
9.70M – 9.70M
+1,840.0% YoY
|
9.90M
9.90M – 9.90M
+2.1% YoY
|
27.80M
27.80M – 27.80M
+180.8% YoY
|
| EBITDA |
-16.19M
|
-34.31M
|
—
— – —
|
—
— – —
|
—
— – —
|
—
— – —
|
| EBIT |
-16.73M
|
-34.43M
|
—
— – —
|
—
— – —
|
—
— – —
|
—
— – —
|
| Net Income |
-16.75M
est: -3.03B (+99.4%)
|
-34.66M
est: -31.48M (-10.1%)
|
-6.18M
-6.18M – -6.18M
+80.4% YoY
|
-4.63M
-4.63M – -4.63M
+25.0% YoY
|
-3.86M
-3.86M – -3.86M
+16.7% YoY
|
-3.48M
-3.48M – -3.48M
+10.0% YoY
|
| SGA |
5.51M
|
5.77M
|
—
— – —
|
—
— – —
|
—
— – —
|
—
— – —
|
| EPS |
-47.14
est: -4,398.24 (+98.9%)
|
-52.59
est: -45.64 (-15.2%)
|
-8.96
-8.96 – -8.96
+80.4% YoY
|
-6.72
-6.72 – -6.72
+25.0% YoY
|
-5.60
-5.60 – -5.60
+16.7% YoY
|
-5.04
-5.04 – -5.04
+10.0% YoY
|
| Date | Rating | Overall | DCF | ROE | ROA | D/E | P/E | P/B |
|---|---|---|---|---|---|---|---|---|
| 2026-05-15 | B- | 2/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 | 5/5 |
| 2026-05-14 | B- | 2/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 | 5/5 |
| 2026-05-13 | B- | 2/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 | 5/5 |
| 2026-05-12 | B- | 2/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 | 5/5 |
| 2026-05-11 | B- | 2/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 | 5/5 |
| 2026-05-08 | B- | 2/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 | 5/5 |
| 2026-05-07 | B- | 2/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 | 5/5 |
| 2026-05-06 | B- | 2/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 | 5/5 |
| 2026-05-05 | B- | 2/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 | 5/5 |
| 2026-05-04 | B- | 2/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 | 5/5 |
| 2026-05-01 | B- | 2/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 | 5/5 |
| 2026-04-30 | B- | 2/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 | 5/5 |
| 2026-04-29 | B- | 2/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 | 5/5 |
| 2026-04-28 | B- | 2/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 | 5/5 |
| 2026-04-27 | C+ | 2/5 | 4/5 | 1/5 | 1/5 | 1/5 | 1/5 | 5/5 |
| 2026-04-24 | B- | 2/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 | 5/5 |
| 2026-04-23 | B- | 2/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 | 5/5 |
| 2026-04-22 | C+ | 2/5 | 4/5 | 1/5 | 1/5 | 1/5 | 1/5 | 5/5 |
| 2026-04-21 | C+ | 2/5 | 4/5 | 1/5 | 1/5 | 1/5 | 1/5 | 5/5 |
| 2026-04-20 | C+ | 2/5 | 4/5 | 1/5 | 1/5 | 1/5 | 1/5 | 5/5 |
| 2026-04-17 | C+ | 2/5 | 4/5 | 1/5 | 1/5 | 1/5 | 1/5 | 5/5 |
| 2026-04-16 | B- | 2/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 | 5/5 |
Owner Earnings
Owner's Earnings history not available.
Ownership Overview
| # | Reporting person | Amount owned | % of class | Sole voting | Shared voting | Sole dispositive | Shared dispositive | Type | Citizenship | Filing date | SEC filing |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Jeff Easton | 2.50M | 9.90% | 2.50M | — | 2.50M | — | IN | Delaware | 2023-12-07 | ↗ |
| 2 | Lind Global Fund II LP | 2.50M | 9.90% | 2.50M | — | 2.50M | — | PN | Delaware | 2023-12-07 | ↗ |
| 3 | Lind Global Partners II LLC | 2.50M | 9.90% | 2.50M | — | 2.50M | — | OO | Delaware | 2023-12-07 | ↗ |
| 4 | Robert Michael Dudley | 1.76M | 12.70% | 1.76M | — | 1.76M | — | IN | United States of America | 2022-12-20 | ↗ |
| 5 | LP | 1.72M | 9.90% | — | 1.72M | — | 1.72M | PN | Delaware, United States | 2024-07-26 | ↗ |
| 6 | Maier Joshua Tarlow | 1.72M | 9.90% | — | 1.72M | — | 1.72M | IN | Delaware, United States | 2024-07-26 | ↗ |
| 7 | Management LLC | 1.72M | 9.90% | — | 1.72M | — | 1.72M | OO | Delaware, United States | 2024-07-26 | ↗ |
| 8 | Zdravka Medarova | 1.62M | 12.50% | 1.62M | — | 1.62M | — | IN | United States of America | 2022-12-20 | ↗ |
| 9 | (. | 1.27M | 9.90% | 1.27M | — | 1.27M | — | IN | Maryland | 2021-07-21 | ↗ |
| 10 | 27-4413262 | 1.27M | 9.90% | 1.27M | — | 1.27M | — | OO | Maryland | 2021-07-21 | ↗ |
| 11 | Thomas A. Fitzgerald | 422.0K | 5.50% | 422.0K | — | 422.0K | — | IN | United States of America | 2024-06-21 | ↗ |
Institutional Activity (13F)
| # | Investor | Shares / Δ | Mkt value / Δ | Own% / Δ | Weight% / Δ | Avg px / Perf. | Hold / Status |
|---|---|---|---|---|---|---|---|
| 1 | GEODE CAPITAL MANAGEMENT, LLC | 12.7K +12.7K (+100.0%) | 109.7K +109.7K (+100.0%) | 1.39% +1.389 pp | 0.00% +0.000 pp | USD8.61 +0.0% | 1 qtrs NEW |
| 2 | UBS GROUP AG | 8.3K +5.3K (+179.9%) | 71.4K +51.2K (+252.8%) | 0.90% +0.475 pp | 0.00% +0.000 pp | USD7.97 +8.0% | 4 qtrs — |
| 3 | — | 6.5K +6.5K (+100.0%) | 56.4K +56.4K (+100.0%) | 0.71% +0.714 pp | 0.00% +0.000 pp | USD8.61 +0.0% | 1 qtrs NEW |
| 4 | VANGUARD FIDUCIARY TRUST CO | 3.0K +3.0K (+100.0%) | 25.7K +25.7K (+100.0%) | 0.33% +0.325 pp | 0.00% +0.000 pp | USD8.61 +0.0% | 1 qtrs NEW |
| 5 | TOWER RESEARCH CAPITAL LLC (TRC) | 228.00 -659.0 (-74.3%) | 2.0K -4.1K (-67.6%) | 0.02% -0.104 pp | 0.00% 0.000 pp | USD6.98 +23.4% | 4 qtrs — |
| 6 | WELLS FARGO & COMPANY/MN | 55.00 +55.0 (+100.0%) | 474.00 +474.0 (+100.0%) | 0.01% +0.006 pp | 0.00% +0.000 pp | USD8.60 +0.1% | 1 qtrs NEW |
| 7 | SBI SECURITIES CO., LTD. | 12.00 +2.0 (+20.0%) | 103.00 +35.0 (+51.5%) | 0.00% 0.000 pp | 0.00% +0.000 pp | USD7.92 +8.7% | 4 qtrs — |
| 8 | ADVISOR GROUP HOLDINGS, INC. | — -3.0 (-100.0%) | — -20.0 (-100.0%) | 0.00% 0.000 pp | 0.00% +0.000 pp | USD— | 4 qtrs SOLD |
ETF Ownership
| # | ETF | Weight | Est. AUM exposure | TER |
|---|---|---|---|---|
| 1 | Vanguard Extended Market ETF VXF | 0.00% | 32.9K | 0.05% |
| 2 | Vanguard Extended Market ETF VXF | 0.00% | 1.0K | 0.05% |
Insider Activity
| Date | Person | Role | Transaction | A/D | Security | Shares | Price | Value | Owned after | D/I | Filing |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-12-19 | STOVER JACK E | Director | — | — | — | 0 | 0.00 | — | 0 | — | ↗ |
| 2025-10-06 | CZEREPAK ELIZABETH | Director | — | — | — | 0 | 0.00 | — | 0 | — | ↗ |
| 2024-06-14 | Marquet Magda | Director | A-Award | A | Stock Option (right to buy) | 70,000 | 1.20 | 84.0K | 70,000 | — | ↗ |
| 2024-06-14 | Manting Erik | Director | A-Award | A | Stock Option (right to buy) | 70,000 | 1.20 | 84.0K | 70,000 | — | ↗ |
| 2024-06-14 | Fitzgerald Thomas A | Director / Officer | A-Award | A | Stock Option (right to buy) | 650,000 | 1.20 | 780.0K | 650,000 | — | ↗ |
| 2024-06-14 | Calais Philippe | Director | A-Award | A | Stock Option (right to buy) | 70,000 | 1.20 | 84.0K | 70,000 | — | ↗ |
| 2023-09-28 | Fitzgerald Thomas A | Director / Officer | P-Purchase | A | Common Stock | 49,350 | 0.51 | 25.2K | 56,318 | — | ↗ |
| 2023-09-28 | Dudley Robert Michael | Director / Officer | P-Purchase | A | Common Stock | 98,000 | 0.51 | 50.0K | 180,262 | — | ↗ |
| 2023-06-21 | Dudley Robert Michael | Director / Officer | P-Purchase | A | Common Stock | 12,000 | 2.65 | 31.8K | 82,262 | — | ↗ |
| 2023-06-20 | Dudley Robert Michael | Director / Officer | P-Purchase | A | Common Stock | 6,607 | 2.55 | 16.8K | 70,262 | — | ↗ |
| 2023-06-09 | Dudley Robert Michael | Director / Officer | P-Purchase | A | Common Stock | 19,000 | 2.76 | 52.4K | 61,155 | — | ↗ |
| 2023-05-19 | Marquet Magda | Director | A-Award | A | Stock Option (right to buy) | 45,000 | 0.28 | 12.8K | 45,000 | — | ↗ |
| 2023-05-19 | Manting Erik | Director | A-Award | A | Stock Option (right to buy) | 45,000 | 0.28 | 12.8K | 45,000 | — | ↗ |
| 2023-05-19 | Fitzgerald Thomas A | Director / Officer | A-Award | A | Stock Option (right to buy) | 300,000 | 0.28 | 85.0K | 300,000 | — | ↗ |
| 2023-05-19 | Dudley Robert Michael | Director / Officer | A-Award | A | Stock Option (right to buy) | 735,000 | 0.28 | 208.3K | 735,000 | — | ↗ |
| 2023-05-19 | Calais Philippe | Director | A-Award | A | Stock Option (right to buy) | 45,000 | 0.28 | 12.8K | 45,000 | — | ↗ |
| 2023-05-10 | Marquet Magda | Director | A-Award | A | Stock Option (Right to Buy) | 9,500 | 0.30 | 2.8K | 9,500 | — | ↗ |
| 2023-05-10 | Manting Erik | Director | A-Award | A | Stock Option (Right to Buy) | 9,500 | 0.30 | 2.8K | 9,500 | — | ↗ |
| 2023-05-10 | Calais Philippe | Director | A-Award | A | Stock Option (Right to Buy) | 9,500 | 0.30 | 2.8K | 9,500 | — | ↗ |
| 2022-12-12 | Medarova Zdravka | Officer | A-Award | A | Stock Option (Right to Buy) | 60,000 | 0.00 | — | 60,000 | — | ↗ |
| 2022-12-12 | Fitzgerald Thomas A | Officer | A-Award | A | Stock Option (Right to Buy) | 100,000 | 0.00 | — | 100,000 | — | ↗ |
| 2022-12-12 | Dudley Robert Michael | Officer | A-Award | A | Stock Option (Right to Buy) | 135,000 | 0.00 | — | 135,000 | — | ↗ |
| 2022-09-14 | Dudley Robert Michael | Director / Officer / 10% Owner | P-Purchase | A | Common Stock | 20,000 | 1.15 | 23.0K | 893,114 | — | ↗ |
| 2022-06-22 | Marquet Magda | Director | A-Award | A | Stock Option (Right to Buy) | 9,500 | 1.24 | 11.8K | 9,500 | — | ↗ |
| 2022-06-22 | Manting Erik | Director | A-Award | A | Stock Option (Right to Buy) | 9,500 | 0.00 | — | 9,500 | — | ↗ |
| 2022-06-22 | Calais Philippe | Director | A-Award | A | Stock Option (Right to Buy) | 9,500 | 0.00 | — | 9,500 | — | ↗ |
| 2022-06-16 | Fitzgerald Thomas A | Officer | P-Purchase | A | Common Stock | 12,000 | 1.27 | 15.2K | 139,377 | — | ↗ |
| 2022-05-27 | Dudley Robert Michael | Officer | P-Purchase | A | Common Stock | 28,000 | 1.84 | 51.6K | 871,114 | — | ↗ |
| 2022-03-01 | Fitzgerald Thomas A | Officer | A-Award | A | Stock Option (Right to Buy) | 52,000 | 0.00 | — | 52,000 | — | ↗ |
| 2022-02-01 | Medarova Zdravka | Officer | A-Award | A | Stock Option (Right to Buy) | 33,000 | 0.00 | — | 33,000 | — | ↗ |
| 2022-02-01 | Fitzgerald Thomas A | Director / Officer | A-Award | A | Stock Option (Right to Buy) | 33,000 | 2.45 | 80.9K | 33,000 | — | ↗ |
| 2022-02-01 | Dudley Robert Michael | Director / Officer / 10% Owner | A-Award | A | Stock Option (Right to Buy) | 135,000 | 2.45 | 330.8K | 135,000 | — | ↗ |
| 2021-07-08 | Marquet Magda | Director | — | D | Stock Option (Right to Buy) | 36,393 | 3.91 | 142.2K | 0 | — | ↗ |
| 2021-07-08 | Manting Erik | Director | — | D | Stock Option (Right to Buy) | 36,393 | 3.91 | 142.2K | 0 | — | ↗ |
| 2021-07-08 | Fitzgerald Thomas A | Director / Officer | — | D | Stock Option (Right to Buy) | 242,622 | 0.08 | 19.9K | 0 | — | ↗ |
| 2021-07-08 | Dudley Robert Michael | Director / Officer / 10% Owner | — | D | Stock Option (Right to Buy) | 818,852 | 0.09 | 74.5K | 0 | — | ↗ |
| 2021-07-08 | Calais Philippe | Director | — | D | Common Stock | 0 | 0.00 | — | 127,377 | — | ↗ |
Executive team
Executive compensation
| # | Year | Executive | Salary | Bonus | Stock award | Option award | Incentive | Other | Total | % Stock- based |
Filing |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 2024 | Thomas A. Fitzgerald Interim Chief Executive Officer, Vice President and Chief Financial Officer | 255.1K | — | — | 701.9K | — | — | 957.0K | 73.35% | ↗ |
| 2 | 2024 | Robert Michael Dudley Former Chief Executive Officer | 85.4K | — | — | — | — | — | 85.4K | 0.00% | ↗ |
| 3 | 2023 | Robert Michael Dudley Former Chief Executive Officer | 474.4K | — | — | 168.4K | — | — | 642.8K | 26.20% | ↗ |
| 4 | 2023 | Thomas A. Fitzgerald Interim Chief Executive Officer, Vice President and Chief Financial Officer | 358.1K | — | — | 68.7K | — | — | 426.9K | 16.10% | ↗ |
| 5 | 2022 | Robert Michael Dudley Former Chief Executive Officer | 494.0K | — | — | 311.0K | — | — | 805.0K | 38.64% | ↗ |
| 6 | 2022 | Robert Michael Dudley Chief Executive Officer | 494.0K | — | — | 311.0K | — | — | 805.0K | 38.64% | ↗ |
| 7 | 2022 | Thomas A. Fitzgerald Interim Chief Executive Officer, Vice President and Chief Financial Officer | 371.0K | — | — | 189.7K | — | — | 560.7K | 33.83% | ↗ |
| 8 | 2022 | Thomas A. Fitzgerald Vice President and Chief Financial Officer | 371.0K | — | — | 189.7K | — | — | 560.7K | 33.83% | ↗ |
| 9 | 2021 | Robert Michael Dudley Chief Executive Officer | 240.0K | 255.5K | — | — | — | — | 495.5K | 0.00% | ↗ |
| 10 | 2021 | Thomas A. Fitzgerald Vice President and Chief Financial Officer | 180.0K | 137.6K | — | — | — | — | 317.6K | 0.00% | ↗ |
| 11 | 2020 | Robert Michael Dudley Chief Executive Officer | — | — | — | 43.0K | — | — | 43.0K | 100.00% | ↗ |
| 12 | 2020 | Thomas A. Fitzgerald Vice President and Chief Financial Officer | — | — | — | 15.4K | — | — | 15.4K | 100.00% | ↗ |
Proxy statements
| Filing date | Form type | Filing |
|---|---|---|
| 2026-05-08 | PRE 14A | ↗ |
| 2026-04-07 | DEFA14A | ↗ |
| 2026-03-03 | DEFA14A | ↗ |
| 2025-12-23 | DEFA14A | ↗ |
| 2025-10-27 | DEFA14A | ↗ |
| 2025-10-17 | DEFA14A | ↗ |
| 2025-10-08 | DEFA14A | ↗ |
| 2025-10-08 | DEFA14A | ↗ |
| 2025-07-15 | DEF 14A | ↗ |
| 2025-04-21 | DEFA14A | ↗ |
| 2025-04-16 | DEFA14A | ↗ |
| 2025-04-11 | DEF 14A | ↗ |
| 2025-04-02 | PRE 14A | ↗ |
| 2025-02-04 | DEFA14A | ↗ |
| 2024-12-30 | DEF 14A | ↗ |
| 2024-12-19 | PRE 14A | ↗ |
| 2024-11-13 | DEFA14A | ↗ |
| 2024-11-06 | DEFA14A | ↗ |
| 2024-10-28 | DEF 14A | ↗ |
| 2024-10-15 | PRE 14A | ↗ |
Recent SEC filings
Executive team
| Name | Title | Compensation | Gender |
|---|---|---|---|
| Thomas A. Fitzgerald | Chief Financial Officer, President, Vice President of Administration & Director | 1M | male |
| Philippe Calais | Chief Executive Officer & Executive Chairman of the Board | 566.1K | — |
| Anna Moore | Scientific Co-Founder, Scientific Advisor & Chair of Scientific Advisory Board | — | — |
| Daniel R. Vlock | Chief Medical Officer | — | — |
| Susan Duggan | Senior Vice President of Operations | — | female |
| Zdravka Medarova | Scientific Co-Founder & Chief Scientific Officer | — | — |
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No House trading activity found for this company.
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Community Opinion for RNAZ
Short-term intention
Target Price Distribution
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