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Rapport Therapeutics, Inc. Common Stock (RAPP)

USD40.28 -1.19 (-2.86%)
US NASDAQ Healthcare Biotechnology
Address 1325 Boylston Street
Boston, DE, US
CEO Abraham N. Ceesay
IPO 2024-06-07
CIK 2012593 ISIN US75383L1026

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Description

Rapport Therapeutics, Inc. functions as a clinical-phase biopharmaceutical enterprise, concentrating its efforts on discovering and developing innovative small-molecule therapeutics for individuals living with central nervous system (CNS) disorders. Its flagship product candidate, RAP-219, is an experimental small molecule precisely designed to inhibit TARPy8-containing AMPARs with exceptional potency (picomolar affinity). This promising compound aims to treat focal epilepsy and a range of other neurological conditions, including peripheral neuropathic pain and bipolar disorder. The company's pipeline further includes RAP-199, another molecule targeting TARPy8, which boasts distinct chemical and pharmacokinetic profiles. Moreover, Rapport is advancing several nicotinic acetylcholine receptor (nAChR) programs, such as an a6 nAChR therapy for chronic pain and an a9a10 nAChR treatment intended for hearing impairments. Formed in 2022 under the initial name Precision Neuroscience NewCo, Inc., the company adopted its current identity as Rapport Therapeutics, Inc. in October 2022, and its operations are based in Boston, Massachusetts.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
USD40.28 -1.19 (-2.86%)
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Volume Profile
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Liquidity & share structure
Average Volume
356.4K
Beta
0.95
Float Shares
17.46M
Free Float %
47.8%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
+1.03% +2.43% +12.47% +37.40% +52.68% +26.66% +267.05% +84.76% +84.76% +84.76% +84.76%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
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Annual Monthly Returns
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Daily Returns Distribution
vs.
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

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By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Analyst Consensus (5 ratings, all time) Buy
Price Targets & DCF
Current price
40.28
Low 40.00 -0.7%
Consensus 49.00 +21.7%
Median 45.00 +11.7%
High 66.00 +63.9%
DCF (Unlevered) 0.79 -98.0%
DCF (Levered) 0.88 -97.8%

DCF figures are point estimates: small changes in growth or discount-rate assumptions move them materially. Read them as a reference, not a precise target.

Ratings Trend (MoM) 100% Bullish
Rating 2026-05 Change
Strong Buy 1 0
Buy 10 0
Hold 0 0
Sell 0 0
Strong Sell 0 0
Price Target Summary
Period # Analysts Avg Target
Last Month 1
66.00
+63.9%
Last Quarter 2
56.50
+40.3%
Last Year 6
48.50
+20.4%
All Time 8
45.13
+12.1%
Quality scores
Altman Z-Score
32.77
Safe zone
Piotroski F-Score
3 / 9
Average
MOAT Score
2 / 10
No MOAT
Composite Rating
C
Overall Score
2 / 5
Medium
DCF Score
2 / 5
Medium
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
3 / 5
Medium
P/E Score
1 / 5
Low
P/Book Score
2 / 5
Medium
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
  • EPS growth Biotechnology: +29.7%
    +24.3% Q1'26: +38.2% (vs Q1'25)
  • FCF margin FCF growth · Biotechnology: +16.2%
    Q1'26: -65.7% (vs Q1'25)
  • EBIT margin Biotechnology: +0.0%
    Q1'26: -121.1% (vs Q1'25)
  • ROIC Biotechnology: -16.1%
    -2,234.7% Q1'26: -1,750.6% (vs Q1'25)
  • Share dilution Biotechnology: -3.4%
    +126.5% Q1'26: +144.9% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    -0.09× Q1'26: -0.11× (vs Q1'25)
Valuation Multiples From To
DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (0.82) × ERP
WACC = 99% × Ke + 1% × Kd (4.0%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Intrinsic value (base): 0.79 Current price: 40.28
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2024
actual
Dec 2025
actual
Dec 2026
7 Rev. Ana.
6 EPS Ana.
Dec 2027
6 EPS Ana.
Dec 2028
7 EPS Ana.
Dec 2029
3 Rev. Ana.
2 EPS Ana.
Dec 2030
6 Rev. Ana.
5 EPS Ana.
Revenue
est: 20.00M (-100.0%)
20.00M
20.00M – 20.00M
+0.0% YoY
— – —
-100.0% YoY
— – —
30.11M
30.11M – 30.11M
65.04M
65.04M – 65.04M
+116.0% YoY
EBITDA
-77.47M
-124.08M
— – —
— – —
— – —
— – —
— – —
EBIT
-78.31M
-125.10M
— – —
— – —
— – —
— – —
— – —
Net Income
-78.31M
est: -79.70M (+1.7%)
-111.48M
est: -135.61M (+17.8%)
-159.73M
-179.90M – -123.36M
-17.8% YoY
-214.84M
-233.08M – -189.88M
-34.5% YoY
-258.46M
-321.12M – -151.37M
-20.3% YoY
-226.28M
-226.28M – -226.28M
+12.5% YoY
-177.73M
-177.73M – -177.73M
+21.5% YoY
SGA
22.12M
30.31M
— – —
— – —
— – —
— – —
— – —
EPS
-3.78
est: -3.70 (-2.1%)
-2.86
est: -2.84 (-0.7%)
-3.35
-3.83 – -2.63
-17.9% YoY
-4.53
-4.96 – -4.04
-35.3% YoY
-5.01
-6.84 – -3.22
-10.5% YoY
-4.82
-4.82 – -4.82
+3.8% YoY
-3.78
-3.78 – -3.78
+21.5% YoY
Recent Grade Changes (3M)
Date Firm Previous New Grade Action
2026-04-22 BTIG Buy Buy Maintain
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-07 C 2/5 2/5 1/5 1/5 3/5 1/5 2/5
2026-05-06 C 2/5 2/5 1/5 1/5 3/5 1/5 2/5
2026-05-05 C 2/5 2/5 1/5 1/5 3/5 1/5 2/5
2026-05-04 C 2/5 2/5 1/5 1/5 3/5 1/5 2/5
2026-05-01 C 2/5 2/5 1/5 1/5 3/5 1/5 2/5
2026-04-30 C 2/5 2/5 1/5 1/5 3/5 1/5 2/5
2026-04-29 C 2/5 2/5 1/5 1/5 3/5 1/5 2/5
2026-04-28 C 2/5 2/5 1/5 1/5 3/5 1/5 2/5
2026-04-27 C 2/5 2/5 1/5 1/5 3/5 1/5 2/5
2026-04-24 C- 1/5 2/5 1/5 1/5 2/5 1/5 2/5
2026-04-23 C 2/5 3/5 1/5 1/5 2/5 1/5 2/5
2026-04-22 C 2/5 3/5 1/5 1/5 2/5 1/5 2/5
2026-04-21 C 2/5 3/5 1/5 1/5 2/5 1/5 2/5
2026-04-20 C 2/5 3/5 1/5 1/5 2/5 1/5 2/5
2026-04-17 C 2/5 3/5 1/5 1/5 2/5 1/5 3/5
2026-04-16 C 2/5 3/5 1/5 1/5 2/5 1/5 3/5

Owner Earnings

Owner's Earnings (history)

Owner's Earnings history not available.

Owner alignment
Owner's Earnings TTM
OE per share TTM
Owner's Yield
Maintenance CapEx ratio
Maint CapEx / Avg PPE

Ownership Overview

Ownership breakdown
At a glance
Institutional holders
28
Total invested
22.64M
Insider transactions (90d)
2
Beneficial owners (>5%)
23
Beneficial owners (>5%)
# Reporting person Amount owned % of class Sole voting Shared voting Sole dispositive Shared dispositive Type Citizenship Filing date SEC filing
1 Abigail P. Johnson 4.98M 13.62% 4.98M IN Delaware 2024-07-10
2 FMR LLC 4.98M 13.62% 4.98M 4.98M HC Delaware 2024-07-10
3 ARCH Venture Fund XII, L.P. 3.73M 10.20% 3.73M 3.73M PN Delaware 2024-11-14
4 Bihua Chen 2.94M 8.04% 2.94M 2.94M IN United States 2024-06-20
5 Cormorant Asset Management, LP 2.94M 8.04% 2.94M 2.94M PN Delaware 2024-06-20
6 GOLDMAN SACHS & CO. LLC 2.67M 7.50% 2.66M 2.67M BD, IA, OO 2024-06-21
7 THE GOLDMAN SACHS GROUP, INC. 2.67M 7.50% 2.66M 2.67M HC, CO 2024-06-21
8 Johnson & Johnson 2.50M 6.80% 2.50M CO New Jersey 2024-10-18
9 Johnson & Johnson Innovation-JJDC, Inc. 2.50M 6.80% 2.50M CO New Jersey 2024-10-18
10 Cormorant Global Healthcare GP, LLC 1.28M 3.51% 1.28M 1.28M OO Delaware 2024-06-20
11 Cormorant Global Healthcare Master Fund, LP 1.28M 3.51% 1.28M 1.28M PN Cayman Islands 2024-06-20
12 Cormorant Global Healthcare GP V, LLC 732.5K 2.00% 732.5K 732.5K OO Delaware 2024-06-20
13 Cormorant Private Healthcare Fund V, LP 732.5K 2.00% 732.5K 732.5K PN Delaware 2024-06-20
14 Cormorant Global Healthcare GP III, LLC 694.4K 1.90% 694.4K 694.4K OO Delaware 2024-06-20
15 Cormorant Private Healthcare Fund III, LP 694.4K 1.90% 694.4K 694.4K PN Delaware 2024-06-20
16 WSLS OFFSHORE INVESTMENTS, SLP 327.1K 0.90% 327.1K 327.1K PN 2024-06-21
17 WEST STREET LIFE SCIENCES I, L.P. 326.6K 0.90% 326.6K PN 2024-06-21
18 WSLS EMP ONSHORE INVESTMENTS, L.P. 237.9K 0.70% 237.9K 237.9K PN 2024-06-21
19 BROAD STREET PRINCIPAL INVESTMENTS, L.L.C. 233.7K 0.70% 233.7K 233.7K OO 2024-06-21
20 Cormorant Global Healthcare GP IV, LLC 229.7K 0.63% 229.7K 229.7K OO Delaware 2024-06-20
21 Cormorant Private Healthcare Fund IV, LP 229.7K 0.63% 229.7K 229.7K PN Delaware 2024-06-20
22 WSLS EMP OFFSHORE INVESTMENTS, L.P. 89.7K 0.30% 89.7K 89.7K PN 2024-06-21
23 95-1411037 13.00 7.10% 2.60M 2.60M IA Delaware 2024-11-13

Institutional Activity (13F)

Institutional ownership trend From To
13F snapshot — 2026 Q1
Investors holding
28
-116 vs prev Q
New positions
5
Closed positions
120
Increased
12
Reduced
7
Put/Call ratio
0.00
Calls held
Puts held
Top institutional holders
# Investor Shares / Δ Mkt value / Δ Own% / Δ Weight% / Δ Avg px / Perf. Hold / Status
1 17.5K +17.5K (+100.0%) 531.13M +531.1M (+100.0%) 0.00% +0.005 pp 0.46% +0.464 pp USD30.34 +0.0% 1 qtrs NEW
2 TRV GP V, LLC 7.14M +— (+0.0%) 216.48M +4.6M (+2.2%) 1.88% -0.132 pp 50.44% -9.508 pp USD17.74 +71.0% 5 qtrs
3 FMR LLC 7.11M +194.9K (+2.8%) 215.77M +10.3M (+5.0%) 1.87% -0.077 pp 0.01% +0.000 pp USD26.09 +16.3% 7 qtrs
4 ARCH VENTURE MANAGEMENT, LLC 3.73M +— (+0.0%) 113.13M +2.4M (+2.2%) 0.98% -0.069 pp 17.36% -5.133 pp USD25.44 +19.3% 7 qtrs
5 CAPITAL INTERNATIONAL INVESTORS 3.40M +— (+0.0%) 103.23M +2.2M (+2.2%) 0.90% -0.063 pp 0.02% 0.000 pp USD26.44 +14.8% 7 qtrs
6 CORMORANT ASSET MANAGEMENT, LP 3.03M -165.0K (-5.2%) 91.85M -3.0M (-3.1%) 0.80% -0.103 pp 4.25% -2.295 pp USD25.77 +17.7% 7 qtrs
7 GOLDMAN SACHS GROUP INC 3.00M +579.9K (+23.9%) 91.08M +19.1M (+26.6%) 7.91% +7.231 pp 0.01% +0.002 pp USD26.03 +16.6% 6 qtrs
8 BLACKROCK, INC. 2.43M +863.8K (+55.1%) 73.78M +27.2M (+58.4%) 6.41% +5.969 pp 0.00% +0.000 pp USD23.14 +31.1% 6 qtrs
9 SOFINNOVA INVESTMENTS, INC. 1.90M -43.2K (-2.2%) 57.78M -63.4K (-0.1%) 0.50% -0.047 pp 2.49% -0.672 pp USD25.33 +19.8% 7 qtrs
10 VANGUARD GROUP INC 1.82M +191.2K (+11.8%) 55.15M +6.8M (+14.2%) 4.79% +4.333 pp 0.00% +0.000 pp USD21.07 +44.0% 7 qtrs
11 JOHNSON & JOHNSON 1.78M +— (+0.0%) 54.14M +1.1M (+2.2%) 4.70% +4.201 pp 9.75% -0.709 pp USD25.44 +19.3% 7 qtrs
12 BAKER BROS. ADVISORS LP 1.55M +— (+0.0%) 46.94M +990.1K (+2.2%) 4.08% +3.642 pp 0.27% -0.057 pp USD23.18 +30.9% 3 qtrs
13 VESTAL POINT CAPITAL, LP 1.11M +160.0K (+16.8%) 33.68M +5.5M (+19.4%) 2.93% +2.658 pp 1.15% -0.129 pp USD29.79 +1.8% 2 qtrs
14 POLAR CAPITAL HOLDINGS PLC 1.00M +65.8K (+7.0%) 30.48M +2.6M (+9.3%) 2.65% +2.384 pp 0.12% -0.016 pp USD29.74 +2.0% 2 qtrs
15 TRV GP VI, LLC 969.2K +— (+0.0%) 29.41M +620.3K (+2.2%) 0.26% -0.018 pp 19.80% -6.460 pp USD17.74 +71.0% 5 qtrs
16 UBS ASSET MANAGEMENT AMERICAS INC 952.4K +60.1K (+6.7%) 28.89M +2.4M (+9.0%) 0.25% -0.001 pp 0.01% +0.000 pp USD24.76 +22.5% 4 qtrs
17 PRICE T ROWE ASSOCIATES INC /MD/ 881.6K -220.8K (-20.0%) 26.75M -6.0M (-18.3%) 2.32% +2.013 pp 0.00% -0.001 pp USD20.81 +45.8% 7 qtrs
18 ALLIANCEBERNSTEIN L.P. 788.4K -67.2K (-7.9%) 23.92M -1.5M (-5.9%) 2.08% +1.837 pp 0.01% 0.000 pp USD24.68 +22.9% 7 qtrs
19 STATE STREET CORP 714.8K +343.2K (+92.3%) 21.69M +10.7M (+96.5%) 1.88% +1.780 pp 0.00% +0.000 pp USD24.02 +26.3% 6 qtrs
20 SIREN, L.L.C. 708.5K -345.0K (-32.7%) 21.49M -9.8M (-31.3%) 0.19% -0.110 pp 0.64% -0.583 pp USD26.39 +15.0% 6 qtrs
21 GEODE CAPITAL MANAGEMENT, LLC 694.7K +161.3K (+30.2%) 21.08M +5.2M (+33.0%) 1.83% +1.681 pp 0.00% +0.000 pp USD23.58 +28.7% 6 qtrs
22 PERCEPTIVE ADVISORS LLC 673.9K +270.0K (+66.8%) 20.45M +8.5M (+70.4%) 1.78% +1.663 pp 0.36% +0.018 pp USD29.96 +1.3% 2 qtrs
23 T. ROWE PRICE INVESTMENT MANAGEMENT, INC. 619.0K -88.5K (-12.5%) 18.78M -2.2M (-10.6%) 1.63% +1.432 pp 0.01% -0.001 pp USD25.53 +18.8% 7 qtrs
24 INVESCO LTD. 267.1K +109.1K (+69.1%) 8.10M +3.4M (+72.7%) 0.70% +0.660 pp 0.00% +0.001 pp USD29.96 +1.3% 2 qtrs
25 PRUDENTIAL FINANCIAL INC 255.0K +255.0K (+100.0%) 7.74M +7.7M (+100.0%) 0.67% +0.672 pp 0.01% +0.009 pp USD30.34 +0.0% 1 qtrs NEW
26 BURKEHILL GLOBAL MANAGEMENT, LP 250.0K +— (+0.0%) 7.59M +160.0K (+2.2%) 0.66% +0.589 pp 0.50% +0.078 pp USD29.70 +2.2% 2 qtrs
27 D. E. SHAW & CO., INC. 247.3K +247.3K (+100.0%) 7.50M +7.5M (+100.0%) 0.07% +0.065 pp 0.00% +0.004 pp USD30.34 +0.0% 1 qtrs NEW
28 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 244.4K +41.9K (+20.7%) 7.41M +1.4M (+23.3%) 0.06% +0.007 pp 0.00% +0.000 pp USD25.44 +19.3% 6 qtrs
29 UBS GROUP AG 226.4K -331.7K (-59.4%) 6.87M -9.7M (-58.6%) 0.60% +0.439 pp 0.00% -0.002 pp USD20.91 +45.1% 7 qtrs
30 NORTHERN TRUST CORP 220.8K +67.0K (+43.5%) 6.70M +2.1M (+46.6%) 0.06% +0.015 pp 0.00% +0.000 pp USD22.66 +33.9% 6 qtrs
31 MORGAN STANLEY 210.3K -64.2K (-23.4%) 6.38M -1.8M (-21.7%) 0.55% +0.477 pp 0.00% 0.000 pp USD25.50 +19.0% 6 qtrs
32 MILLENNIUM MANAGEMENT LLC 201.8K +47.7K (+30.9%) 6.12M +1.5M (+33.7%) 0.53% +0.489 pp 0.00% +0.001 pp USD29.85 +1.6% 2 qtrs
33 ENSIGN PEAK ADVISORS, INC 194.2K +— (+0.0%) 5.89M +124.3K (+2.2%) 0.05% -0.004 pp 0.01% +0.001 pp USD10.03 +202.5% 4 qtrs
34 SIO CAPITAL MANAGEMENT, LLC 185.3K +— (+0.0%) 5.62M +118.6K (+2.2%) 0.49% +0.436 pp 0.88% -0.508 pp USD29.70 +2.2% 2 qtrs
35 KENNEDY CAPITAL MANAGEMENT LLC 178.7K +178.7K (+100.0%) 5.42M +5.4M (+100.0%) 0.05% +0.047 pp 0.11% +0.115 pp USD30.34 +0.0% 3 qtrs
36 ADAGE CAPITAL PARTNERS GP, L.L.C. 150.0K -300.0K (-66.7%) 4.55M -8.8M (-65.9%) 0.40% +0.269 pp 0.01% -0.014 pp USD29.70 +2.2% 2 qtrs
37 ARTIA GLOBAL PARTNERS LP 138.5K +73.9K (+114.4%) 4.20M +2.3M (+119.0%) 0.37% +0.347 pp 0.67% +0.366 pp USD30.04 +1.0% 2 qtrs
38 RENAISSANCE TECHNOLOGIES LLC 118.8K +83.5K (+236.6%) 3.60M +2.6M (+243.8%) 0.31% +0.303 pp 0.01% +0.004 pp USD27.74 +9.4% 3 qtrs
39 TD ASSET MANAGEMENT INC 115.2K -21.8K (-15.9%) 3.49M -574.5K (-14.1%) 0.03% -0.008 pp 0.00% -0.001 pp USD18.86 +60.9% 7 qtrs
40 SWEDBANK AB 113.2K +113.2K (+100.0%) 3.43M +3.4M (+100.0%) 0.03% +0.030 pp 0.00% +0.003 pp USD30.34 +0.0% 1 qtrs NEW
41 EAM INVESTORS, LLC 85.6K -1.7K (-2.0%) 2.60M +45.8K (+1.8%) 0.02% -0.002 pp 0.29% -0.003 pp USD29.70 +2.2% 2 qtrs
42 DIMENSIONAL FUND ADVISORS LP 83.5K +72.2K (+636.9%) 2.53M +2.2M (+652.7%) 0.02% +0.019 pp 0.00% +0.001 pp USD30.25 +0.3% 2 qtrs
43 MANUFACTURERS LIFE INSURANCE COMPANY, THE 78.7K -3.7K (-4.5%) 2.41M -38.1K (-1.6%) 0.02% -0.003 pp 0.00% +0.000 pp USD22.08 +37.4% 7 qtrs
44 DAFNA CAPITAL MANAGEMENT LLC 75.0K +— (+0.0%) 2.28M +48.0K (+2.2%) 0.02% -0.001 pp 0.53% -0.022 pp USD29.70 +2.2% 2 qtrs
45 BANK OF NEW YORK MELLON CORP 74.1K +26.7K (+56.2%) 2.25M +839.2K (+59.6%) 0.02% +0.006 pp 0.00% +0.000 pp USD22.18 +36.8% 6 qtrs
46 NUVEEN, LLC 70.9K +49.1K (+224.4%) 2.15M +1.5M (+231.3%) 0.19% +0.181 pp 0.00% +0.000 pp USD24.08 +26.0% 4 qtrs
47 VOYA INVESTMENT MANAGEMENT LLC 66.1K +52.8K (+395.8%) 2.01M +1.6M (+406.5%) 0.02% +0.014 pp 0.00% +0.002 pp USD30.21 +0.4% 2 qtrs
48 TREXQUANT INVESTMENT LP 63.0K +42.5K (+206.9%) 1.91M +1.3M (+213.5%) 0.17% +0.160 pp 0.02% +0.011 pp USD30.13 +0.7% 2 qtrs
49 EVERSEPT PARTNERS, LP 59.2K -84.3K (-58.7%) 1.80M -2.5M (-57.9%) 0.16% +0.116 pp 0.09% -0.203 pp USD29.70 +2.2% 2 qtrs
50 CITIGROUP INC 56.5K +54.7K (+3,091.2%) 1.71M +1.7M (+3,160.0%) 0.01% +0.014 pp 0.00% +0.001 pp USD29.91 +1.4% 6 qtrs
51 WELLINGTON MANAGEMENT GROUP LLP 56.5K -6.4K (-10.1%) 1.71M -152.9K (-8.2%) 0.01% -0.003 pp 0.00% +0.000 pp USD29.70 +2.2% 2 qtrs
52 SWISS NATIONAL BANK 54.6K +54.6K (+100.0%) 1.66M +1.7M (+100.0%) 0.01% +0.014 pp 0.00% +0.001 pp USD30.34 +0.0% 1 qtrs NEW
53 BARCLAYS PLC 52.5K +39.6K (+308.0%) 1.59M +1.3M (+504.4%) 0.14% +0.135 pp 0.00% +0.000 pp USD26.17 +15.9% 7 qtrs
54 TWO SIGMA INVESTMENTS, LP 50.6K +29.1K (+135.4%) 1.54M +897.2K (+140.5%) 0.13% +0.127 pp 0.00% +0.001 pp USD22.40 +35.4% 4 qtrs
55 AMERICAN CENTURY COMPANIES INC 46.8K +28.6K (+156.7%) 1.42M +879.4K (+162.2%) 0.01% +0.007 pp 0.00% +0.000 pp USD30.09 +0.8% 2 qtrs
56 ACADIAN ASSET MANAGEMENT LLC 44.3K +42.8K (+2,896.7%) 1.34M +1.3M (+3,016.3%) 0.01% +0.011 pp 0.00% +0.002 pp USD30.32 +0.1% 2 qtrs
57 ALPS ADVISORS INC 39.1K +22.0K (+128.9%) 1.19M +679.5K (+133.8%) 0.01% +0.006 pp 0.01% +0.004 pp USD24.83 +22.2% 5 qtrs
58 SECTORAL ASSET MANAGEMENT INC 38.9K -4.6K (-10.5%) 1.18M -110.4K (-8.5%) 0.01% -0.002 pp 0.95% +0.150 pp USD11.37 +166.8% 3 qtrs
59 EXODUSPOINT CAPITAL MANAGEMENT, LP 34.7K +34.7K (+100.0%) 1.05M +1.1M (+100.0%) 0.09% +0.091 pp 0.01% +0.008 pp USD30.34 +0.0% 1 qtrs NEW
60 BANK OF AMERICA CORP /DE/ 34.6K -23.5K (-40.5%) 1.05M -676.1K (-39.2%) 0.09% +0.075 pp 0.00% +0.000 pp USD26.88 +12.9% 6 qtrs
61 WELLS FARGO & COMPANY/MN 32.1K +18.6K (+138.5%) 974.2K +574.4K (+143.7%) 0.08% +0.081 pp 0.00% +0.000 pp USD24.72 +22.7% 6 qtrs
62 RHUMBLINE ADVISERS 30.7K +6.4K (+26.5%) 932.2K +210.9K (+29.2%) 0.08% +0.074 pp 0.00% +0.000 pp USD18.13 +67.3% 6 qtrs
63 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 26.7K +25.6K (+2,335.2%) 809.8K +777.2K (+2,387.7%) 0.01% +0.007 pp 0.00% +0.001 pp USD29.60 +2.5% 6 qtrs
64 JANE STREET GROUP, LLC 26.0K -160.1K (-86.0%) 788.8K -4.7M (-85.7%) 0.07% +0.016 pp 0.00% -0.001 pp USD29.70 +2.2% 2 qtrs
65 LEGAL & GENERAL GROUP PLC 22.4K -11.5K (-34.0%) 679.1K -327.5K (-32.5%) 0.01% -0.004 pp 0.00% 0.000 pp USD29.10 +4.3% 6 qtrs
66 DEUTSCHE BANK AG\ 21.5K +15.3K (+244.6%) 653.4K +467.8K (+252.0%) 0.01% +0.004 pp 0.00% +0.000 pp USD25.24 +20.2% 5 qtrs
67 DARK FOREST CAPITAL MANAGEMENT LP 21.1K +21.1K (+100.0%) 639.4K +639.4K (+100.0%) 0.01% +0.006 pp 0.03% +0.029 pp USD30.34 +0.0% 1 qtrs NEW
68 AQR CAPITAL MANAGEMENT LLC 20.9K +256.0 (+1.2%) 633.4K +21.0K (+3.4%) 0.01% 0.000 pp 0.00% 0.000 pp USD14.81 +104.9% 3 qtrs
69 SEI INVESTMENTS CO 18.3K +10.1K (+124.1%) 554.3K +312.1K (+128.9%) 0.00% +0.003 pp 0.00% +0.000 pp USD30.05 +1.0% 2 qtrs
70 CITADEL ADVISORS LLC 16.9K -17.7K (-51.2%) 512.7K -514.9K (-50.1%) 0.04% +0.035 pp 0.00% 0.000 pp USD29.70 +2.2% 4 qtrs
71 BREVAN HOWARD CAPITAL MANAGEMENT LP 16.8K +16.8K (+100.0%) 509.2K +509.2K (+100.0%) 0.04% +0.044 pp 0.01% +0.006 pp USD30.34 +0.0% 1 qtrs NEW
72 METLIFE INVESTMENT MANAGEMENT, LLC 16.0K +5.1K (+47.3%) 485.3K +162.7K (+50.4%) 0.00% +0.001 pp 0.00% +0.001 pp USD20.28 +49.6% 6 qtrs
73 JPMORGAN CHASE & CO 15.1K +5.1K (+51.5%) 459.0K +162.5K (+54.8%) 0.00% +0.001 pp 0.00% +0.000 pp USD21.08 +43.9% 6 qtrs
74 AMERIPRISE FINANCIAL INC 14.8K -110.0K (-88.1%) 448.9K -3.3M (-87.9%) 0.00% -0.031 pp 0.00% -0.001 pp USD29.70 +2.2% 2 qtrs
75 JANUS HENDERSON GROUP PLC 13.8K +13.8K (+100.0%) 418.7K +418.7K (+100.0%) 0.00% +0.004 pp 0.00% +0.000 pp USD30.34 +0.0% 1 qtrs NEW
76 MIRAE ASSET GLOBAL ETFS HOLDINGS LTD. 13.2K +5.2K (+64.5%) 402.0K +162.8K (+68.1%) 0.00% +0.001 pp 0.00% +0.000 pp USD21.36 +42.0% 6 qtrs
77 ALLIANZ ASSET MANAGEMENT GMBH 13.2K +13.2K (+100.0%) 400.5K +400.5K (+100.0%) 0.00% +0.004 pp 0.00% +0.000 pp USD30.34 +0.0% 1 qtrs NEW
78 XTX TOPCO LTD 13.1K +13.1K (+100.0%) 396.3K +396.3K (+100.0%) 0.03% +0.034 pp 0.01% +0.010 pp USD30.34 +0.0% 1 qtrs NEW
79 GSA CAPITAL PARTNERS LLP 12.7K +12.7K (+100.0%) 386.0K +386.0K (+100.0%) 0.00% +0.003 pp 0.03% +0.033 pp USD30.34 +0.0% 1 qtrs NEW
80 BNP PARIBAS ARBITRAGE, SNC 12.4K +5.1K (+71.1%) 374.8K +160.4K (+74.8%) 0.03% +0.031 pp 0.00% +0.000 pp USD27.95 +8.6% 6 qtrs
81 CREATIVE PLANNING 12.2K +253.0 (+2.1%) 370.5K +15.3K (+4.3%) 0.00% 0.000 pp 0.00% +0.000 pp USD13.80 +119.9% 3 qtrs
82 CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD. 10.8K +3.4K (+45.5%) 326.6K +106.9K (+48.7%) 0.00% +0.001 pp 0.03% +0.007 pp USD21.76 +39.4% 5 qtrs
83 SUSQUEHANNA INTERNATIONAL GROUP, LLP 10.2K -10.9K (-51.7%) 309.7K -318.2K (-50.7%) 0.03% +0.021 pp 0.00% +0.000 pp USD10.05 +201.9% 4 qtrs
84 CATALYST PRIVATE WEALTH, LLC 10.0K +— (+0.0%) 303.4K +6.4K (+2.2%) 0.00% 0.000 pp 0.13% +0.002 pp USD10.03 +202.5% 4 qtrs
85 SILVERARC CAPITAL MANAGEMENT, LLC 9.7K -194.3K (-95.3%) 293.1K -5.8M (-95.2%) 0.00% -0.055 pp 0.04% -0.776 pp USD29.70 +2.2% 2 qtrs
86 SG AMERICAS SECURITIES, LLC 9.7K +3.4K (+54.4%) 293.0K +107.0K (+57.5%) 0.00% +0.001 pp 0.00% 0.000 pp USD29.93 +1.4% 2 qtrs
87 CANADA PENSION PLAN INVESTMENT BOARD 9.1K +9.1K (+100.0%) 276.1K +276.1K (+100.0%) 0.02% +0.024 pp 0.00% +0.000 pp USD30.34 +0.0% 1 qtrs NEW
88 PROFUND ADVISORS LLC 8.9K +8.9K (+100.0%) 269.4K +269.4K (+100.0%) 0.00% +0.002 pp 0.01% +0.008 pp USD30.34 +0.0% 1 qtrs NEW
89 QUADRATURE CAPITAL LTD 8.8K +8.8K (+100.0%) 268.1K +268.1K (+100.0%) 0.02% +0.023 pp 0.00% +0.003 pp USD30.34 +0.0% 1 qtrs NEW
90 VIRTUS INVESTMENT ADVISERS, INC. 8.8K -1.4K (-14.0%) 266.7K -36.7K (-12.1%) 0.02% +0.020 pp 0.07% -0.014 pp USD13.44 +125.7% 4 qtrs
91 STATE OF WISCONSIN INVESTMENT BOARD 8.3K +8.3K (+100.0%) 251.7K +251.7K (+100.0%) 0.00% +0.002 pp 0.00% +0.001 pp USD30.34 +0.0% 1 qtrs NEW
92 INTECH INVESTMENT MANAGEMENT LLC 8.0K +8.0K (+100.0%) 243.5K +243.5K (+100.0%) 0.00% +0.002 pp 0.00% +0.002 pp USD30.34 +0.0% 3 qtrs
93 SQUAREPOINT OPS LLC 7.9K +7.9K (+100.0%) 238.4K +238.4K (+100.0%) 0.00% +0.002 pp 0.00% +0.000 pp USD30.34 +0.0% 1 qtrs NEW
94 SUSQUEHANNA PORTFOLIO STRATEGIES, LLC 7.0K -500.0 (-6.6%) 213.3K -10.4K (-4.6%) 0.02% +0.016 pp 0.00% 0.000 pp USD29.70 +2.2% 2 qtrs
95 SANDIA INVESTMENT MANAGEMENT LP 6.0K +— (+0.0%) 182.0K +3.8K (+2.2%) 0.02% +0.014 pp 0.45% -0.077 pp USD29.70 +2.2% 2 qtrs
96 STERLING CAPITAL MANAGEMENT LLC 1.6K +429.0 (+35.4%) 49.8K +13.8K (+38.3%) 0.00% +0.004 pp 0.00% +0.000 pp USD25.15 +20.6% 6 qtrs
97 CWM, LLC 1.5K +10.0 (+0.7%) 45.0K +2.0K (+4.7%) 0.00% +0.004 pp 0.00% +0.000 pp USD12.51 +142.5% 4 qtrs
98 NISA INVESTMENT ADVISORS, LLC 1.4K +— (+0.0%) 41.1K +866.0 (+2.2%) 0.00% +0.003 pp 0.00% +0.000 pp USD11.37 +166.8% 5 qtrs
99 ROYAL BANK OF CANADA 1.1K +8.0 (+0.7%) 33.0K +1.0K (+3.1%) 0.00% +0.003 pp 0.00% +0.000 pp USD17.42 +74.2% 7 qtrs
Ownership breakdown by holder

ETF Ownership

Top ETFs holding this stock Held by 92 ETFs in our universe
# ETF Weight Est. AUM exposure TER
1 State Street SPDR S&P Pharmaceuticals ETF XPH 1.38% 6.49M 0.35%
2 ALPS Medical Breakthroughs ETF SBIO 1.02% 2.17M 0.50%
3 Virtus Biotech Clinical Trials ETF BBC 0.67% 385.2K 0.65%
4 Invesco Dorsey Wright SmallCap Momentum ETF DWAS 0.48% 2.26M 0.60%
5 iShares Micro-Cap ETF IWC 0.29% 4.28M 0.60%
6 Direxion Daily Pharmaceutical & Medical Bull 3X ETF PILL 0.29% 66.7K 1.22%
7 iShares U.S. Pharmaceuticals ETF IHE 0.27% 3.61M 0.38%
8 Vanguard U.S. Momentum Factor ETF VFMO 0.15% 2.59M 0.13%
9 Invesco NASDAQ Biotech UCITS ETF SBIO.L 0.14% 635.5K 0.40%
10 Invesco Nasdaq Biotechnology ETF IBBQ 0.14% 102.7K 0.19%

Insider Activity

Insider Activity — Latest Quarter
Ratio by transactions
0.00
Bearish
Ratio by volume
0.00
Bearish
Buys
0
Sells
4
Shares acquired
Shares disposed
20.2K
Cash buys
Cash sales
4.00
Net activity
-20,225
Insider buys vs sells (history) From To
Recent insider transactions From To
Date Person Role Transaction A/D Security Shares Price Value Owned after D/I Filing
2026-04-17 Yeleswaram Krishnaswamy Officer S-Sale D Common Stock 20,225 39.99 808.8K 246,426 D
2026-04-17 Third Rock Ventures V, L.P. 10% Owner S-Sale D Common Stock 426,005 40.32 17.18M 6,709,228 D
2026-04-14 Yeleswaram Krishnaswamy Officer S-Sale D Common Stock 10,200 35.08 357.8K 266,651 D
2026-04-13 Yeleswaram Krishnaswamy Officer S-Sale D Common Stock 9,165 34.97 320.5K 276,851 D
2026-04-10 Yeleswaram Krishnaswamy Officer S-Sale D Common Stock 500 34.98 17.5K 286,016 D
2026-04-08 Yeleswaram Krishnaswamy Officer S-Sale D Common Stock 360 34.90 12.6K 286,516 D
2026-03-30 Gault Cheryl Officer S-Sale D Common Stock 7,161 28.04 200.8K 162,753 D
2026-03-25 Yeleswaram Krishnaswamy Officer S-Sale D Common Stock 10,115 29.99 303.4K 286,876 D
2026-03-05 Gault Cheryl Officer S-Sale D Common Stock 2,014 28.93 58.3K 169,914 D
2026-02-19 Bredt David Officer M-Exempt D Stock Options (Right to Buy) 6,000 1.80 10.8K 88,080 D
2026-02-18 Ceesay Abraham Director / Officer S-Sale D Common Stock 2,100 29.80 62.6K 20,729 I
2026-02-17 Bredt David Officer S-Sale D Common Stock 900 28.02 25.2K 394,675 D
2026-02-02 Yeleswaram Krishnaswamy Officer A-Award A Stock Option (Right to Buy) 120,000 27.75 3.33M 120,000 D
2026-02-02 Sevigny Jeffrey Officer A-Award A Stock Option (Right to Buy) 130,000 27.75 3.61M 130,000 D
2026-02-02 Ignelzi Troy A. Officer A-Award A Stock Option (Right to Buy) 148,000 27.75 4.11M 148,000 D
2026-02-02 Gault Cheryl Officer A-Award A Stock Option (Right to Buy) 132,000 27.75 3.66M 132,000 D
2026-02-02 Ceesay Abraham Director / Officer A-Award A Stock Option (Right to Buy) 428,000 27.75 11.88M 428,000 D
2026-02-02 Bredt David Officer A-Award A Stock Option (Right to Buy) 103,000 27.75 2.86M 103,000 D
2026-01-20 Ceesay Abraham Director / Officer S-Sale D Common Stock 5,833 26.12 152.3K 562,080 D
2026-01-15 Bredt David Officer S-Sale D Common Stock 8,300 26.83 222.7K 395,775 D
2025-12-31 Yeleswaram Krishnaswamy Officer A-Award A Common Stock 9,000 0.00 299,831 D
2025-12-31 Bredt David Officer A-Award D Common Stock 18,000 0.00 410,642 D
2025-12-17 Ceesay Abraham Director / Officer S-Sale D Common Stock 600 31.04 18.6K 567,913 D
2025-12-15 Bredt David Officer S-Sale D Common Stock 7,704 29.95 230.7K 393,438 D
2025-11-26 Gault Cheryl Officer M-Exempt A Common Stock 5,000 1.80 9.0K 176,928 D
2025-11-17 Ceesay Abraham Director / Officer S-Sale D Common Stock 2,777 24.92 69.2K 576,802 D
2025-11-17 Bredt David Officer S-Sale D Common Stock 3,156 24.84 78.4K 406,486 D
2025-10-15 Ceesay Abraham Director / Officer S-Sale D Common Stock 4,647 25.72 119.5K 580,765 D
2025-10-15 Bredt David Officer S-Sale D Common Stock 7,418 25.73 190.9K 410,724 D
2025-09-17 Ceesay Abraham Director / Officer S-Sale D Common Stock 39,435 26.30 1.04M 586,812 D
2025-09-15 Bredt David Officer S-Sale D Common Stock 3,402 24.66 83.9K 418,142 D
2025-09-12 PAUL STEVEN M Director P-Purchase A Common Stock 28,284 24.50 692.9K 28,284 I
2025-09-12 Huber Reid M Director P-Purchase A Common Stock 20,400 24.48 499.4K 20,400 D
2025-09-11 Young Wendy B. Director P-Purchase A Common Stock 3,500 22.60 79.1K 9,500 D
2025-09-08 Gault Cheryl Officer M-Exempt A Common Stock 5,000 1.80 9.0K 176,928 D
2025-08-15 Bredt David Officer S-Sale D Common Stock 8,300 14.98 124.3K 426,842 D
2025-07-15 Bredt David Officer S-Sale D Common Stock 8,500 14.00 119.0K 435,142 D
2025-06-17 Young Wendy B. Director A-Award A Stock Option (Right to Buy) 10,925 10.95 119.6K 10,925 D
2025-06-17 Silva Paul M Director A-Award A Stock Option (Right to Buy) 10,925 10.95 119.6K 10,925 D
2025-06-17 Sanchez Ramiro Director A-Award A Stock Option (Right to Buy) 10,925 10.95 119.6K 10,925 D
2025-06-17 PEREZ ROBERT J Director A-Award A Stock Option (Right to Buy) 10,925 10.95 119.6K 10,925 D
2025-06-17 PAUL STEVEN M Director A-Award A Stock Option (Right to Buy) 21,850 10.95 239.3K 21,850 D
2025-06-17 MARAGANORE JOHN Director A-Award A Stock Option (Right to Buy) 21,850 10.95 239.3K 21,850 D
2025-06-17 Huber Reid M Director A-Award A Stock Option (Right to Buy) 21,850 10.95 239.3K 21,850 D
2025-06-17 HEALY JAMES Director A-Award A Stock Option (Right to Buy) 21,850 10.95 239.3K 21,850 D
2025-06-16 Bredt David Officer S-Sale D Common Stock 8,500 11.00 93.5K 443,642 D
2025-05-15 Bredt David Officer S-Sale D Common Stock 8,500 9.56 81.3K 452,142 D
2025-04-15 Bredt David Officer S-Sale D Common Stock 8,500 9.57 81.3K 460,642 D
2025-04-01 Sevigny Jeffrey Officer A-Award A Stock Option (Right to Buy) 300,000 9.56 2.87M 300,000 D
2025-03-14 Bredt David Officer S-Sale D Common Stock 8,500 10.85 92.2K 469,142 D
2025-03-13 Ignelzi Troy A. Officer P-Purchase A Common Stock 100 9.98 998.00 10,000 D
2025-03-12 Young Wendy B. Director P-Purchase A Common Stock 6,000 10.21 61.2K 6,000 D
2025-03-12 Ignelzi Troy A. Officer P-Purchase A Common Stock 9,900 10.10 100.0K 9,900 D
2025-03-03 Sevigny Jeffrey 0 0.00 0
2025-03-03 Gault Cheryl Officer A-Award A Common Stock 13,987 0.00 171,928 D
2025-02-03 Yeleswaram Krishnaswamy Officer A-Award A Stock Option (Right to Buy) 110,000 16.60 1.83M 110,000 D
2025-02-03 Ignelzi Troy A. Officer A-Award A Stock Option (Right to Buy) 142,000 16.60 2.36M 142,000 D
2025-02-03 Gault Cheryl Officer A-Award A Stock Option (Right to Buy) 129,000 16.60 2.14M 129,000 D
2025-02-03 Ceesay Abraham Director / Officer A-Award A Stock Option (Right to Buy) 428,000 16.60 7.10M 428,000 D
2025-02-03 Bredt David Officer A-Award A Stock Option (Right to Buy) 100,000 16.60 1.66M 100,000 D
2024-11-07 Young Wendy B. Director A-Award A Stock Option (Right to Buy) 29,756 26.90 800.4K 29,756 D
2024-11-07 Silva Paul M 0 0.00 0
2024-11-07 Sanchez Ramiro Director A-Award A Stock Option (Right to Buy) 29,756 26.90 800.4K 29,756 D
2024-11-07 PEREZ ROBERT J 0 0.00 0

Executive team

Top executives
Shares Outstanding
36.50M

Executive compensation

Executive compensation (annual)
# Year Executive Salary Bonus Stock award Option award Incentive Other Total % Stock-
based
Filing
1 2025 Abraham Ceesay, M.B.A. Chief Executive Officer 652.9K 5.16M 431.1K 24.8K 6.27M 82.30%
2 2025 Jeffrey Sevigny, M.D. 561.1K 2.10M 283.8K 77.8K 3.02M 69.49%
3 2025 Troy Ignelzi Chief Financial Officer 519.8K 1.71M 249.6K 25.9K 2.51M 68.26%
4 2024 Abraham Ceesay, M.B.A. Chief Executive Officer 576.5K 8.95M 293.6K 21.2K 9.84M 90.94%
5 2024 Abraham Ceesay, M.B.A. Chief Executive Officer 576.5K 8.95M 293.6K 21.2K 9.84M 90.94%
6 2024 Troy Ignelzi Chief Financial Officer 468.5K 1.79M 170.0K 37.1K 2.46M 72.59%
7 2024 Troy Ignelzi Chief Financial Officer 468.5K 1.79M 170.0K 37.1K 2.46M 72.59%
8 2024 Bradley Galer, M.D. Former Chief Medical Officer 466.9K 75.0K 1.71M 163.2K 18.4K 2.43M 70.24%
9 2023 Abraham Ceesay, M.B.A. Chief Executive Officer 400.1K 250.0K 1.51M 231.2K 20.8K 2.42M 62.66%
10 2023 Troy Ignelzi Chief Financial Officer 69.5K 2.02M 35.8K 7.1K 2.13M 94.73%
CEO compensation breakdown

Proxy statements

Proxy statements (DEF 14A)
Filing date Form type Filing
2026-04-23 DEFA14A
2026-04-23 DEF 14A
2025-04-24 DEFA14A
2025-04-24 DEF 14A

Recent SEC filings

Recent SEC filings
Filing date Form type Filing
2026-05-07 8-K
2026-05-07 10-Q
2026-04-23 DEFA14A
2026-04-23 DEF 14A
2026-04-23 ARS
2026-04-21 8-K
2026-04-21 4
2026-04-21 4
2026-04-14 4
2026-04-09 4

Executive team

NameTitleCompensationGender
Abraham N. Ceesay Chief Executive Officer, President, Treasurer & Director 1M male
Jeffrey Sevigny Chief Medical Officer 1M
Troy A. Ignelzi Chief Financial Officer 795.4K
Cheryl Gault Chief Operating Officer 281.1K female
Steven Paul Founder & Independent Chairman 44.0K
Arnold R. Gammaitoni Senior Vice President of Medical Affairs
Brian Corcoran Controller
Karina Chmielewski Chief Information Officer & Head of Operations female
Kathleen A. Wilkinson Chief People Officer female
Swamy Yeleswaram Chief Development Officer male
Julie DiCarlo Head of Communications & Investor Relations female
David Bredt Founder & Chief Scientific Officer male
ESG Rating
B
2026
E (Environmental)
58.3
S (Social)
63.3
G (Governance)
60.8
ESG Total
60.8
ESG Score History
Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend history

Earnings history

Earnings reports

Stock splits