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ProQR Therapeutics N.V. (PRQR)
USD1.73
+0.03 (+1.47%)
NL NASDAQ Healthcare Biotechnology
Address
Zernikedreef 9 2333 Ck
Leiden, NL
Leiden, NL
CEO
Daniel Anton de Boer
Website
proqr.com
IPO
2014-09-18
CIK 1612940 ISIN NL0010872495
Description
ProQR Therapeutics N.V. operates as a biopharmaceutical enterprise dedicated to discovering and developing RNA-based therapies designed to address genetic disorders. The company's pipeline includes two primary drug candidates in advanced clinical stages: Sepofarsen is currently in a Phase II/III clinical trial, known as the ILLUMINATE trial, targeting Leber Congenital Amaurosis 10 (LCA10). Ultevursen is also undergoing Phase II/III evaluation for the treatment of USH2A-mediated retinitis pigmentosa and Usher syndrome. Beyond its clinical programs, ProQR is actively developing its proprietary Axiomer RNA base-editing platform technology. Strategic collaborations are central to ProQR's strategy, evidenced by its licensing agreements with institutions such as Radboud University Medical Center, Inserm Transfert SA, Ionis Pharmaceuticals, Inc., and Leiden University Medical Center. Furthermore, a significant license and research partnership exists with Eli Lilly and Company, focused on the discovery, advancement, and commercialization of novel medicines for genetic conditions impacting the liver and nervous system. Established in 2012, ProQR Therapeutics N.V. maintains its corporate headquarters in Leiden, the Netherlands.
News Sentiment (7d)
Based on only 1 article — low confidence
Market Cap & Enterprise Value
Merger & Acquisition History
No mergers or acquisitions recorded for this company.
Technical Outlook
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Signal Summary
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| Indicator | 1D | 1W | 2W | 3W | 1M |
|---|
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
USD1.73
+0.03 (+1.47%)
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Volume Profile
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Liquidity & share structure
Average Volume
881.4K
Beta
0.06
Float Shares
64.35M
Free Float %
61.1%
Price Performance
| 1D | 5D | 1M | 3M | 6M | YTD | 1Y | 3Y | 5Y | 10Y | Max |
|---|---|---|---|---|---|---|---|---|---|---|
| -2.94% | +5.10% | -17.09% | +13.01% | -23.96% | -18.32% | +6.45% | -14.06% | -74.26% | -65.84% | -88.80% |
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From
To
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Annual Monthly Returns
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Daily Returns Distribution
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Revenue flow
Revenue by geography
Revenue by segment
From
To
Revenue composition
From
To
By product
By geography
Financial Statements
Select metrics from the tables below to build your comparison.
Income Statement
Balance Sheet
Cash Flow Statement
Key Metrics
Financial Ratios
Employees
Financial Growth (CAGR)
Market Data
Analyst Consensus (10 ratings, all time)
Buy
Price Targets & DCF
Current price
1.73
Low
2.00
+15.9%
Consensus
3.63
+110.4%
Median
3.75
+117.4%
High
5.00
+189.9%
Ratings Trend (MoM)
100% Bullish
| Rating | 2026-05 | Change |
|---|---|---|
| Strong Buy | 1 | 0 |
| Buy | 7 | 0 |
| Hold | 0 | 0 |
| Sell | 0 | 0 |
| Strong Sell | 0 | 0 |
Price Target Summary
| Period | # Analysts | Avg Target |
|---|---|---|
| Last Month | — | — |
| Last Quarter | — | — |
| Last Year | — | — |
| All Time | 4 |
3.63
+110.4%
|
Quality scores
Altman Z-Score
-6.05
Distress
Piotroski F-Score
0 / 9
Weak
MOAT Score
1 / 10
No MOAT
Composite Rating
C
Overall Score
2 / 5
Medium
DCF Score
3 / 5
Medium
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
2 / 5
Medium
P/E Score
1 / 5
Low
P/Book Score
2 / 5
Medium
Operational MOAT
✗ Below peers
-
Revenue growth Biotechnology: +1.6%-19.2% Q1'26: -54.3% (vs Q1'25)
-
EPS growth Biotechnology: +29.7%-11.8% Q1'26: -30.0% (vs Q1'25)
-
FCF margin FCF growth · Biotechnology: +16.2%-380.6% Q1'26: -556.3% (vs Q1'25)
-
EBIT margin Biotechnology: +0.0%-275.9% Q1'26: -671.4% (vs Q1'25)
-
ROIC Biotechnology: -16.1%— Q1'26: +186.0% (vs Q1'25)
-
Share dilution Biotechnology: -3.4%+29.0% Q1'26: +0.1% (vs Q1'25)
-
Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×-0.35× Q1'26: -0.26× (vs Q1'25)
Valuation Multiples
From
To
Price Forecast (3Y)
From
To
Theoretical Return — If Invested Today
* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.
Consensus Estimates
| Metric |
Dec 2015 actual |
Dec 2016 actual |
Dec 2017 actual |
Dec 2018 actual |
Dec 2019 actual |
Dec 2020 actual |
Dec 2021 actual |
Dec 2022 actual |
Dec 2023 actual |
Dec 2024 actual |
Dec 2025 actual |
Dec 2026 4 Rev. Ana. 3 EPS Ana. |
Dec 2027 3 Rev. Ana. 3 EPS Ana. |
Dec 2028 3 Rev. Ana. 3 EPS Ana. |
Dec 2029 2 Rev. Ana. 1 EPS Ana. |
Dec 2030 1 Rev. Ana. 1 EPS Ana. |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue |
9.41M
est: 2.16M (+335.6%)
|
2.28M
est: 1.96M (+16.7%)
|
-1.53M
est: 1.08M (-242.1%)
|
4.94M
est: 5.22M (-5.4%)
|
1.93M
est: 1.99M (-3.1%)
|
1.03M
est: 9.30M (-88.9%)
|
1.34M
est: 2.57M (-48.1%)
|
3.59M
est: 22.14M (-83.8%)
|
6.51M
est: 14.70M (-55.7%)
|
18.91M
est: 17.45M (+8.3%)
|
15.28M
est: 16.24M (-5.9%)
|
21.01M
18.89M – 22.95M
+29.4% YoY
|
17.11M
9.75M – 22.70M
-18.6% YoY
|
59.76M
58.89M – 60.63M
+249.4% YoY
|
72.63M
53.81M – 88.50M
+21.5% YoY
|
138.78M
102.82M – 169.11M
+91.1% YoY
|
| EBITDA |
-84.24M
est: -2.16M (-3,801.1%)
|
-120.55M
est: -1.96M (-6,062.8%)
|
—
est: -1.08M (+100.0%)
|
-35.29M
est: -31.80M (-11.0%)
|
-174.27M
est: -48.84M (-256.8%)
|
-48.44M
est: -37.05M (-30.7%)
|
-54.95M
est: -43.37M (-26.7%)
|
-56.46M
est: -56.56M (+0.2%)
|
-24.10M
est: -14.70M (-63.9%)
|
-24.12M
est: -17.45M (-38.2%)
|
-39.56M
est: -16.24M (-143.6%)
|
-21.01M
-22.95M – -18.89M
-29.4% YoY
|
-17.11M
-22.70M – -9.75M
+18.6% YoY
|
-59.76M
-60.63M – -58.89M
-249.4% YoY
|
-72.63M
-88.50M – -53.81M
-21.5% YoY
|
-138.78M
-169.11M – -102.82M
-91.1% YoY
|
| EBIT |
36.80M
est: -2.16M (+1,804.3%)
|
-37.21M
est: -1.96M (-1,802.2%)
|
—
est: -1.08M (+100.0%)
|
-36.28M
est: -31.13M (-16.5%)
|
-172.35M
est: -52.43M (-228.7%)
|
-50.79M
est: -37.75M (-34.5%)
|
-57.28M
est: -41.79M (-37.1%)
|
-58.98M
est: -59.72M (+1.2%)
|
-26.61M
est: -14.70M (-81.0%)
|
-26.88M
est: -17.45M (-54.0%)
|
-42.15M
est: -16.24M (-159.5%)
|
-21.01M
-22.95M – -18.89M
-29.4% YoY
|
-17.11M
-22.70M – -9.75M
+18.6% YoY
|
-59.76M
-60.63M – -58.89M
-249.4% YoY
|
-72.63M
-88.50M – -53.81M
-21.5% YoY
|
-138.78M
-169.11M – -102.82M
-91.1% YoY
|
| Net Income |
-20.83M
est: -80.30M (+74.1%)
|
-39.10M
est: -138.91M (+71.8%)
|
-43.64M
est: -130.40M (+66.5%)
|
-36.89M
est: -31.58M (-16.8%)
|
-56.75M
est: -51.32M (-10.6%)
|
-46.57M
est: -41.71M (-11.6%)
|
-60.74M
est: -45.09M (-34.7%)
|
-64.42M
est: -54.23M (-18.8%)
|
-28.12M
est: -20.07M (-40.1%)
|
-27.76M
est: -33.86M (+18.0%)
|
-40.52M
est: -43.29M (+6.4%)
|
-50.32M
-66.01M – -45.05M
-16.3% YoY
|
-63.90M
-87.94M – -41.04M
-27.0% YoY
|
-29.67M
-41.57M – -17.76M
+53.6% YoY
|
-32.98M
-42.35M – -21.87M
-11.2% YoY
|
3.57M
2.37M – 4.59M
+110.8% YoY
|
| SGA |
6.84M
est: 14.99M (-54.4%)
|
9.48M
est: 13.58M (-30.2%)
|
10.84M
est: 7.47M (+45.1%)
|
12.54M
est: 36.25M (-65.4%)
|
12.89M
est: 13.85M (-6.9%)
|
13.69M
est: 64.57M (-78.8%)
|
17.37M
est: 17.86M (-2.8%)
|
18.65M
est: 18.70M (-0.3%)
|
16.24M
est: 65.67M (-75.3%)
|
13.66M
est: 77.97M (-82.5%)
|
14.12M
est: 72.57M (-80.5%)
|
93.88M
84.40M – 102.54M
+29.4% YoY
|
76.43M
43.55M – 101.43M
-18.6% YoY
|
267.00M
263.11M – 270.89M
+249.4% YoY
|
324.49M
240.42M – 395.41M
+21.5% YoY
|
620.02M
459.38M – 755.53M
+91.1% YoY
|
| EPS |
-0.89
est: -0.98 (+9.5%)
|
-1.67
est: -1.70 (+1.8%)
|
-1.72
est: -1.60 (-7.7%)
|
-1.08
est: -0.95 (-13.1%)
|
-1.38
est: -1.34 (-2.7%)
|
-0.93
est: -0.92 (-1.3%)
|
-0.96
est: -0.90 (-6.5%)
|
-0.91
est: -0.93 (+2.6%)
|
-0.35
est: -0.25 (-41.9%)
|
-0.34
est: -0.33 (-2.0%)
|
-0.38
est: -0.41 (+6.5%)
|
-0.53
-0.63 – -0.43
-29.7% YoY
|
-0.60
-0.83 – -0.39
-14.4% YoY
|
-0.30
-0.39 – -0.17
+50.6% YoY
|
-0.31
-0.40 – -0.21
-5.2% YoY
|
0.03
0.02 – 0.04
+110.8% YoY
|
Historical Ratings (3M)
| Date | Rating | Overall | DCF | ROE | ROA | D/E | P/E | P/B |
|---|---|---|---|---|---|---|---|---|
| 2026-05-11 | C | 2/5 | 3/5 | 1/5 | 1/5 | 2/5 | 1/5 | 2/5 |
| 2026-05-08 | C | 2/5 | 3/5 | 1/5 | 1/5 | 2/5 | 1/5 | 2/5 |
| 2026-05-07 | C | 2/5 | 3/5 | 1/5 | 1/5 | 2/5 | 1/5 | 2/5 |
| 2026-05-06 | C | 2/5 | 3/5 | 1/5 | 1/5 | 2/5 | 1/5 | 2/5 |
| 2026-05-05 | C | 2/5 | 3/5 | 1/5 | 1/5 | 2/5 | 1/5 | 2/5 |
| 2026-05-04 | C | 2/5 | 3/5 | 1/5 | 1/5 | 2/5 | 1/5 | 2/5 |
| 2026-05-01 | C | 2/5 | 3/5 | 1/5 | 1/5 | 2/5 | 1/5 | 2/5 |
| 2026-04-30 | C | 2/5 | 3/5 | 1/5 | 1/5 | 2/5 | 1/5 | 2/5 |
| 2026-04-29 | C | 2/5 | 3/5 | 1/5 | 1/5 | 2/5 | 1/5 | 2/5 |
| 2026-04-28 | C | 2/5 | 3/5 | 1/5 | 1/5 | 2/5 | 1/5 | 2/5 |
| 2026-04-27 | C | 2/5 | 3/5 | 1/5 | 1/5 | 2/5 | 1/5 | 2/5 |
| 2026-04-24 | C- | 1/5 | 3/5 | 1/5 | 1/5 | 1/5 | 1/5 | 2/5 |
| 2026-04-23 | C- | 1/5 | 3/5 | 1/5 | 1/5 | 1/5 | 1/5 | 2/5 |
| 2026-04-22 | C- | 1/5 | 3/5 | 1/5 | 1/5 | 1/5 | 1/5 | 2/5 |
| 2026-04-21 | C- | 1/5 | 3/5 | 1/5 | 1/5 | 1/5 | 1/5 | 2/5 |
| 2026-04-20 | C- | 1/5 | 3/5 | 1/5 | 1/5 | 1/5 | 1/5 | 2/5 |
| 2026-04-17 | C- | 1/5 | 3/5 | 1/5 | 1/5 | 1/5 | 1/5 | 2/5 |
| 2026-04-16 | C- | 1/5 | 3/5 | 1/5 | 1/5 | 1/5 | 1/5 | 2/5 |
Owner Earnings
Owner's Earnings (history)
From
To
Owner alignment
Owner's Earnings TTM
-59.99M
OE per share TTM
-0.57
Owner's Yield
-36.17%
Maintenance CapEx ratio
—
Maint CapEx / Avg PPE
215.0%
Ownership Overview
Ownership breakdown
At a glance
Institutional holders
12
Total invested
5.85M
Insider transactions (90d)
0
Beneficial owners (>5%)
27
Beneficial owners (>5%)
| # | Reporting person | Amount owned | % of class | Sole voting | Shared voting | Sole dispositive | Shared dispositive | Type | Citizenship | Filing date | SEC filing |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Wellington Group Holdings LLP | 5.32M | 10.78% | — | 4.91M | — | — | HC | Massachusetts | 2019-11-08 | ↗ |
| 2 | Wellington Investment Advisors Holdings LLP | 5.32M | 10.78% | — | 4.91M | — | — | HC | Massachusetts | 2019-11-08 | ↗ |
| 3 | Wellington Management Group LLP | 5.32M | 10.78% | — | 4.91M | — | — | HC | Massachusetts | 2019-11-08 | ↗ |
| 4 | Wellington Management Company LLP | 5.08M | 10.29% | — | 4.91M | — | — | IA | Massachusetts | 2019-11-08 | ↗ |
| 5 | Patrick Johan Hendrik Krol | 4.83M | 6.80% | 4.83M | — | 4.83M | — | IN | The Netherlands | 2022-02-04 | ↗ |
| 6 | Privium Fund Management B.V. | 4.77M | 6.70% | 4.77M | — | 4.77M | — | FI | The Netherlands | 2022-02-04 | ↗ |
| 7 | Stichting Aescap Life Sciences | 4.77M | 6.70% | 4.77M | — | 4.77M | — | FI | The Netherlands | 2022-02-04 | ↗ |
| 8 | Abigail P. Johnson | 4.46M | 6.27% | — | — | 4.46M | — | IN | United States of America | 2022-02-09 | ↗ |
| 9 | FMR LLC | 4.46M | 6.27% | — | — | 4.46M | — | HC | — | 2022-02-09 | ↗ |
| 10 | A. van Herk Holding B.V. | 4.28M | 5.30% | — | 4.28M | — | — | CO | The Netherlands | 2023-09-14 | ↗ |
| 11 | Adrianus van Herk | 4.28M | 5.30% | — | 4.28M | — | — | IN | The Netherlands | 2023-09-14 | ↗ |
| 12 | Onroerend Goed Beheer- en Beleggingsmaatschappij A. van Herk B.V. | 4.28M | 5.30% | — | 4.28M | — | — | CO | The Netherlands | 2023-09-14 | ↗ |
| 13 | Stichting Administratiekantoor Abchrys | 4.28M | 5.30% | — | 4.28M | — | — | OO | The Netherlands | 2023-09-14 | ↗ |
| 14 | Stichting Administratiekantoor Penulata | 4.28M | 5.30% | — | 4.28M | — | — | OO | The Netherlands | 2023-09-14 | ↗ |
| 15 | Van Herk Investments B.V. | 4.28M | 5.30% | 4.28M | — | 4.28M | — | CO | The Netherlands | 2023-09-14 | ↗ |
| 16 | Van Herk Investments THI B.V. | 4.28M | 5.30% | — | 4.28M | — | — | CO | The Netherlands | 2023-09-14 | ↗ |
| 17 | Van Herk Management Services B.V. | 4.28M | 5.30% | — | 4.28M | — | — | CO | The Netherlands | 2023-09-14 | ↗ |
| 18 | Van Herk Private Equity Investments B.V. | 4.28M | 5.30% | — | 4.28M | — | — | CO | The Netherlands | 2023-09-14 | ↗ |
| 19 | 35-0470950 | 3.99M | 5.60% | 3.99M | — | 3.99M | — | CO | Indiana | 2021-09-10 | ↗ |
| 20 | GOLDMAN SACHS & CO. LLC | 3.97M | 5.60% | — | 3.97M | — | 3.97M | BD, IA, OO | Delaware | 2022-02-07 | ↗ |
| 21 | THE GOLDMAN SACHS GROUP, INC. | 3.97M | 5.60% | — | 3.97M | — | 3.97M | HC, CO | Delaware | 2022-02-07 | ↗ |
| 22 | RTW Investments, LP | 3.57M | 9.22% | — | 3.57M | — | 3.57M | IA, PN, OO | Delaware | 2019-02-22 | ↗ |
| 23 | Roderick Wong | 3.57M | 9.22% | — | 3.57M | — | 3.57M | HC, IN | Delaware | 2019-02-22 | ↗ |
| 24 | Identification #52-2069785 (formerly 13-2631108) | 3.00M | 11.00% | 3.00M | — | — | 3.00M | IA | Delaware | 2019-02-01 | ↗ |
| 25 | RTW Master Fund, Ltd. | 2.57M | 6.63% | — | 2.57M | — | 2.57M | CO | Delaware | 2019-02-22 | ↗ |
| 26 | UBS Group AG directly and on behalf of certain subsidiaries | 2.08M | 5.39% | — | 2.08M | — | 2.08M | BK | Switzerland | 2019-02-15 | ↗ |
| 27 | Inspirational Visions BV | 35.4K | 0.10% | 35.4K | — | 35.4K | — | FI | The Netherlands | 2022-02-04 | ↗ |
Institutional Activity (13F)
Institutional ownership trend
From
To
13F snapshot — 2026 Q1
Investors holding
12
-55 vs prev Q
New positions
2
Closed positions
56
Increased
3
Reduced
1
Put/Call ratio
0.00
Calls held
—
Puts held
—
Top institutional holders
| # | Investor | Shares / Δ | Mkt value / Δ | Own% / Δ | Weight% / Δ | Avg px / Perf. | Hold / Status |
|---|---|---|---|---|---|---|---|
| 1 | MACQUARIE MANAGEMENT HOLDINGS, INC. | 620.0K +620.0K (+100.0%) | 1.25B +1.3B (+100.0%) | 0.59% +0.589 pp | 0.00% +0.002 pp | USD2.02 +0.0% | 1 qtrs NEW |
| 2 | NANO CAP NEW MILLENNIUM GROWTH FUND L P | 10.0K +10.0K (+100.0%) | 20.20M +20.2M (+100.0%) | 0.01% +0.010 pp | 0.02% +0.017 pp | USD2.02 +0.0% | 1 qtrs NEW |
| 3 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 6.25M +— (+0.0%) | 12.63M -687.9K (-5.2%) | 5.94% 0.000 pp | 0.02% -0.002 pp | USD5.37 -62.4% | 33 qtrs — |
| 4 | PRIVIUM FUND MANAGEMENT B.V. | 5.36M +359.5K (+7.2%) | 10.82M +176.3K (+1.7%) | 5.09% +0.341 pp | 1.99% +0.079 pp | USD6.61 -69.4% | 17 qtrs — |
| 5 | ABRDN PLC | 2.95M +651.9K (+28.4%) | 5.96M +1.1M (+21.7%) | 2.80% +0.619 pp | 0.01% +0.002 pp | USD1.60 +26.3% | 4 qtrs — |
| 6 | AFFINITY ASSET ADVISORS, LLC | 2.45M -1.1M (-31.8%) | 4.96M -2.7M (-35.3%) | 2.33% -1.088 pp | 0.28% -0.386 pp | USD2.43 -16.9% | 5 qtrs — |
| 7 | SIO CAPITAL MANAGEMENT, LLC | 2.16M +89.0K (+4.3%) | 4.37M -48.4K (-1.1%) | 2.05% +0.085 pp | 0.69% -0.431 pp | USD2.62 -22.9% | 5 qtrs — |
| 8 | DAFNA CAPITAL MANAGEMENT LLC | 1.57M +— (+0.0%) | 3.17M -172.4K (-5.2%) | 1.49% +0.000 pp | 0.74% -0.089 pp | USD2.35 -14.0% | 14 qtrs — |
| 9 | KYNAM CAPITAL MANAGEMENT, LP | 1.57M -83.1K (-5.0%) | 3.16M -349.4K (-9.9%) | 1.49% -0.079 pp | 0.20% -0.060 pp | USD2.65 -23.8% | 5 qtrs — |
| 10 | IKARIAN CAPITAL, LLC | 1.49M +600.0K (+67.2%) | 3.01M +1.1M (+58.6%) | 1.42% +0.570 pp | 0.24% +0.043 pp | USD2.03 -0.5% | 3 qtrs — |
| 11 | MORGAN STANLEY | 1.37M -1.5M (-52.9%) | 2.76M -3.4M (-55.3%) | 1.30% -1.456 pp | 0.00% 0.000 pp | USD1.85 +9.2% | 46 qtrs — |
| 12 | PLATINUM INVESTMENT MANAGEMENT LTD | 1.24M +— (+0.0%) | 2.50M -135.9K (-5.2%) | 1.17% +0.000 pp | 0.58% +0.407 pp | USD2.65 -23.8% | 5 qtrs — |
| 13 | ARROWMARK COLORADO HOLDINGS LLC | 1.16M -81.5K (-6.5%) | 2.35M -301.7K (-11.4%) | 1.11% -0.077 pp | 0.05% +0.003 pp | USD2.57 -21.4% | 5 qtrs — |
| 14 | M28 CAPITAL MANAGEMENT LP | 1.02M +— (+0.0%) | 2.06M -112.1K (-5.2%) | 0.97% +0.000 pp | 1.50% -1.696 pp | USD2.23 -9.4% | 16 qtrs — |
| 15 | TWO SIGMA INVESTMENTS, LP | 839.4K +422.1K (+101.1%) | 1.70M +806.7K (+90.8%) | 0.80% +0.401 pp | 0.00% +0.001 pp | USD2.15 -6.0% | 30 qtrs — |
| 16 | POINT72 ASSET MANAGEMENT, L.P. | 813.7K +63.7K (+8.5%) | 1.64M +46.1K (+2.9%) | 0.77% +0.060 pp | 0.00% -0.001 pp | USD2.60 -22.3% | 5 qtrs — |
| 17 | UBS GROUP AG | 797.7K +703.1K (+743.6%) | 1.61M +1.4M (+700.1%) | 0.76% +0.667 pp | 0.00% +0.000 pp | USD2.09 -3.3% | 14 qtrs — |
| 18 | WALLEYE CAPITAL LLC | 591.8K +59.8K (+11.2%) | 1.20M +62.3K (+5.5%) | 0.56% +0.057 pp | 0.00% -0.001 pp | USD2.44 -17.2% | 5 qtrs — |
| 19 | CITADEL ADVISORS LLC | 583.2K -73.8K (-11.2%) | 1.18M -221.3K (-15.8%) | 0.55% -0.070 pp | 0.00% +0.000 pp | USD2.00 +1.0% | 12 qtrs — |
| 20 | TWO SIGMA ADVISERS, LP | 452.4K +223.8K (+97.9%) | 913.8K +426.9K (+87.7%) | 0.43% +0.212 pp | 0.00% +0.001 pp | USD1.98 +2.0% | 18 qtrs — |
| 21 | MILLENNIUM MANAGEMENT LLC | 435.0K +194.4K (+80.8%) | 878.7K +366.2K (+71.4%) | 0.41% +0.185 pp | 0.00% +0.000 pp | USD2.36 -14.4% | 21 qtrs — |
| 22 | MONACO ASSET MANAGEMENT SAM | 428.8K -31.2K (-6.8%) | 866.2K -113.6K (-11.6%) | 0.41% -0.030 pp | 0.15% +0.091 pp | USD1.24 +62.9% | 16 qtrs — |
| 23 | BOOTHBAY FUND MANAGEMENT, LLC | 355.3K +107.0K (+43.1%) | 717.7K +188.8K (+35.7%) | 0.34% +0.102 pp | 0.01% +0.003 pp | USD2.64 -23.5% | 13 qtrs — |
| 24 | RAYMOND JAMES FINANCIAL INC | 342.9K +232.6K (+211.0%) | 692.6K +457.8K (+194.9%) | 0.33% +0.221 pp | 0.00% +0.000 pp | USD2.19 -7.8% | 5 qtrs — |
| 25 | NORTHERN TRUST CORP | 294.7K +— (+0.0%) | 595.4K -32.4K (-5.2%) | 0.28% +0.000 pp | 0.00% +0.000 pp | USD2.62 -22.9% | 12 qtrs — |
| 26 | PALO ALTO INVESTORS LP | 188.8K +— (+0.0%) | 381.4K -20.8K (-5.2%) | 0.18% +0.000 pp | 0.05% -0.021 pp | USD2.13 -5.2% | 2 qtrs — |
| 27 | BANK OF AMERICA CORP /DE/ | 173.9K +54.7K (+45.9%) | 351.3K +97.4K (+38.4%) | 0.17% +0.052 pp | 0.00% +0.000 pp | USD2.23 -9.4% | 22 qtrs — |
| 28 | DIADEMA PARTNERS LP | 167.5K +9.8K (+6.2%) | 338.4K +2.5K (+0.8%) | 0.16% +0.009 pp | 0.06% -0.028 pp | USD2.32 -12.9% | 5 qtrs — |
| 29 | JANE STREET GROUP, LLC | 160.2K +149.4K (+1,388.5%) | 323.6K +300.6K (+1,311.6%) | 0.15% +0.142 pp | 0.00% +0.000 pp | USD1.98 +2.0% | 5 qtrs — |
| 30 | BNP PARIBAS ARBITRAGE, SNC | 157.1K +17.6K (+12.6%) | 317.4K +20.1K (+6.8%) | 0.15% +0.017 pp | 0.00% +0.000 pp | USD1.97 +2.5% | 17 qtrs — |
| 31 | FRANKLIN STREET ADVISORS INC /NC | 150.0K +— (+0.0%) | 303.0K -16.5K (-5.2%) | 0.14% +0.000 pp | 0.02% -0.001 pp | USD3.98 -49.2% | 32 qtrs — |
| 32 | XTX TOPCO LTD | 117.9K +107.7K (+1,057.4%) | 238.2K +216.5K (+997.6%) | 0.11% +0.102 pp | 0.01% +0.005 pp | USD2.03 -0.5% | 5 qtrs — |
| 33 | DEUTSCHE BANK AG\ | 108.8K +— (+0.0%) | 219.7K -12.0K (-5.2%) | 0.10% +0.000 pp | 0.00% +0.000 pp | USD1.98 +2.0% | 21 qtrs — |
| 34 | QUADRATURE CAPITAL LTD | 104.2K +68.1K (+188.4%) | 210.5K +133.4K (+172.9%) | 0.10% +0.065 pp | 0.00% +0.001 pp | USD2.06 -1.9% | 4 qtrs — |
| 35 | RESOURCES INVESTMENT ADVISORS, LLC. | 85.0K +5.0K (+6.3%) | 171.7K +1.3K (+0.8%) | 0.08% +0.005 pp | 0.00% 0.000 pp | USD1.89 +6.9% | 11 qtrs — |
| 36 | GEODE CAPITAL MANAGEMENT, LLC | 84.9K +36.1K (+73.9%) | 171.5K +67.5K (+64.9%) | 0.08% +0.034 pp | 0.00% +0.000 pp | USD4.92 -58.9% | 31 qtrs — |
| 37 | LYNX1 CAPITAL MANAGEMENT LP | 68.5K +68.5K (+100.0%) | 138.3K +138.3K (+100.0%) | 0.07% +0.065 pp | 0.03% +0.028 pp | USD2.02 +0.0% | 1 qtrs NEW |
| 38 | PERSISTENT ASSET PARTNERS LTD | 45.2K +8.9K (+24.5%) | 91.2K +13.9K (+18.0%) | 0.04% +0.008 pp | 0.04% -0.012 pp | USD1.47 +37.4% | 4 qtrs — |
| 39 | VELAN CAPITAL INVESTMENT MANAGEMENT LP | 45.0K +— (+0.0%) | 90.9K -5.0K (-5.2%) | 0.04% +0.000 pp | 0.05% -0.037 pp | USD2.52 -19.8% | 5 qtrs — |
| 40 | SIMPLEX TRADING, LLC | 44.3K +44.3K (+100.0%) | 89.4K +89.4K (+100.0%) | 0.04% +0.042 pp | 0.00% +0.000 pp | USD2.02 +0.0% | 14 qtrs — |
| 41 | GROUP ONE TRADING, L.P. | 30.4K +30.4K (+100.0%) | 61.4K +61.4K (+100.0%) | 0.03% +0.029 pp | 0.00% +0.000 pp | USD2.02 +0.0% | 3 qtrs — |
| 42 | FIFTH THIRD BANCORP | 30.0K +— (+0.0%) | 60.6K -3.3K (-5.2%) | 0.03% +0.000 pp | 0.00% +0.000 pp | USD2.13 -5.2% | 2 qtrs — |
| 43 | RFG ADVISORY, LLC | 30.0K +— (+0.0%) | 60.6K -3.3K (-5.2%) | 0.03% +0.000 pp | 0.00% 0.000 pp | USD2.10 -3.8% | 8 qtrs — |
| 44 | INVESCO LTD. | 25.3K +25.3K (+100.0%) | 51.2K +51.2K (+100.0%) | 0.02% +0.024 pp | 0.00% +0.000 pp | USD2.02 +0.0% | 1 qtrs NEW |
| 45 | MOODY LYNN & LIEBERSON, LLC | 25.0K +25.0K (+100.0%) | 50.5K +50.5K (+100.0%) | 0.02% +0.024 pp | 0.00% +0.003 pp | USD2.02 +0.0% | 1 qtrs NEW |
| 46 | VANGUARD PERSONALIZED INDEXING MANAGEMENT, LLC | 22.3K +— (+0.0%) | 45.1K -2.5K (-5.2%) | 0.02% +0.000 pp | 0.00% +0.000 pp | USD3.59 -43.7% | 16 qtrs — |
| 47 | PNC FINANCIAL SERVICES GROUP, INC. | 20.1K +570.0 (+2.9%) | 40.6K -997.0 (-2.4%) | 0.02% +0.001 pp | 0.00% +0.000 pp | USD2.58 -21.7% | 5 qtrs — |
| 48 | — | 20.0K +20.0K (+100.0%) | 40.4K +40.4K (+100.0%) | 0.02% +0.019 pp | 0.01% +0.006 pp | USD2.02 +0.0% | 1 qtrs NEW |
| 49 | MARINER, LLC | 19.2K +— (+0.0%) | 38.8K -2.1K (-5.2%) | 0.02% +0.000 pp | 0.00% +0.000 pp | USD3.62 -44.2% | 13 qtrs — |
| 50 | GUGGENHEIM CAPITAL LLC | 17.2K +17.2K (+100.0%) | 34.8K +34.8K (+100.0%) | 0.02% +0.016 pp | 0.00% +0.000 pp | USD2.02 +0.0% | 1 qtrs NEW |
| 51 | ATOM INVESTORS LP | 13.1K +— (+0.0%) | 26.5K -1.4K (-5.2%) | 0.01% +0.000 pp | 0.00% +0.000 pp | USD0.90 +124.4% | 16 qtrs — |
| 52 | TRUIST FINANCIAL CORP | 10.0K +— (+0.0%) | 20.2K -1.1K (-5.2%) | 0.01% +0.000 pp | 0.00% +0.000 pp | USD1.62 +24.7% | 11 qtrs — |
| 53 | ADAR1 CAPITAL MANAGEMENT, LLC | 10.0K +— (+0.0%) | 20.2K -1.1K (-5.2%) | 0.01% +0.000 pp | 0.00% -0.001 pp | USD2.65 -23.8% | 5 qtrs — |
| 54 | ROYAL BANK OF CANADA | 10.3K -81.9K (-88.8%) | 20.0K -176.0K (-89.8%) | 0.01% -0.078 pp | 0.00% +0.000 pp | USD2.04 -1.0% | 7 qtrs — |
| 55 | WELLS FARGO & COMPANY/MN | 4.0K -1.6K (-28.7%) | 8.1K -3.9K (-32.4%) | 0.00% -0.002 pp | 0.00% +0.000 pp | USD5.90 -65.8% | 43 qtrs — |
| 56 | BLACKROCK, INC. | 3.9K +— (+0.0%) | 8.0K -434.0 (-5.2%) | 0.00% +0.000 pp | 0.00% +0.000 pp | USD2.62 -22.9% | 6 qtrs — |
| 57 | STEWARD PARTNERS INVESTMENT ADVISORY, LLC | 1.3K +— (+0.0%) | 2.6K -143.0 (-5.2%) | 0.00% +0.000 pp | 0.00% +0.000 pp | USD2.34 -13.7% | 5 qtrs — |
| 58 | TOWER RESEARCH CAPITAL LLC (TRC) | 1.2K +318.0 (+35.6%) | 2.4K +544.0 (+28.6%) | 0.00% +0.000 pp | 0.00% +0.000 pp | USD2.10 -3.8% | 2 qtrs — |
| 59 | PFS PARTNERS, LLC | 1.0K +— (+0.0%) | 2.0K -110.0 (-5.2%) | 0.00% +0.000 pp | 0.00% 0.000 pp | USD3.70 -45.4% | 13 qtrs — |
| 60 | FARTHER FINANCE ADVISORS, LLC | 1.0K +1.0K (+100.0%) | 2.0K +2.0K (+100.0%) | 0.00% +0.001 pp | 0.00% +0.000 pp | USD2.02 +0.0% | 1 qtrs NEW |
| 61 | SBI SECURITIES CO., LTD. | 515.00 -37.0 (-6.7%) | 1.0K -136.0 (-11.6%) | 0.00% +0.000 pp | 0.00% +0.000 pp | USD1.56 +29.5% | 5 qtrs — |
| 62 | JPMORGAN CHASE & CO | 283.00 -185.0 (-39.5%) | 572.00 -425.0 (-42.6%) | 0.00% 0.000 pp | 0.00% +0.000 pp | USD2.64 -23.5% | 28 qtrs — |
| 63 | TD WATERHOUSE CANADA INC. | 40.00 +— (+0.0%) | 80.00 -6.0 (-7.0%) | 0.00% +0.000 pp | 0.00% +0.000 pp | USD1.80 +12.2% | 6 qtrs — |
| 64 | ROCKEFELLER CAPITAL MANAGEMENT L.P. | 34.00 +— (+0.0%) | 69.00 -3.0 (-4.2%) | 0.00% +0.000 pp | 0.00% +0.000 pp | USD2.12 -4.7% | 2 qtrs — |
| 65 | ADVISOR GROUP HOLDINGS, INC. | — -6.0K (-100.0%) | — -13.5K (-100.0%) | 0.00% -0.006 pp | 0.00% +0.000 pp | USD— | 20 qtrs SOLD |
| 66 | KESTRA ADVISORY SERVICES, LLC | — -10.0K (-100.0%) | — -21.3K (-100.0%) | 0.00% -0.010 pp | 0.00% 0.000 pp | USD— | 21 qtrs SOLD |
| 67 | WOODLINE PARTNERS LP | — -92.1K (-100.0%) | — -196.3K (-100.0%) | 0.00% -0.088 pp | 0.00% -0.001 pp | USD— | 5 qtrs SOLD |
| 68 | ACTIVEST WEALTH MANAGEMENT | — -100.0 (-100.0%) | — -213.0 (-100.0%) | 0.00% 0.000 pp | 0.00% +0.000 pp | USD— | 4 qtrs SOLD |
| 69 | MACQUARIE GROUP LTD | — -620.0K (-100.0%) | — -1.3M (-100.0%) | 0.00% -0.589 pp | 0.00% -0.002 pp | USD— | 20 qtrs SOLD |
| 70 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | — -25.2K (-100.0%) | — -53.8K (-100.0%) | 0.00% -0.024 pp | 0.00% +0.000 pp | USD— | 2 qtrs SOLD |
| 71 | CITIGROUP INC | — -22.7K (-100.0%) | — -48.4K (-100.0%) | 0.00% -0.022 pp | 0.00% +0.000 pp | USD— | 2 qtrs SOLD |
| 72 | SIREN, L.L.C. | — -1.6M (-100.0%) | — -3.3M (-100.0%) | 0.00% -1.473 pp | 0.00% -0.129 pp | USD— | 5 qtrs SOLD |
Ownership breakdown by holder
ETF Ownership
Top ETFs holding this stock
Held by 6 ETFs in our universe
| # | ETF | Weight | Est. AUM exposure | TER |
|---|---|---|---|---|
| 1 | Xtrackers S&P 500 Swap UCITS ETF XS5G.L | 0.00% | 104.3K | 0.20% |
| 2 | Xtrackers S&P 500 Swap UCITS ETF 5C EUR Hedged XS5E.DE | 0.00% | 104.3K | 0.20% |
| 3 | Xtrackers S&P 500 Swap UCITS ETF 1C XSPU.L | 0.00% | 104.4K | 0.15% |
| 4 | Xtrackers S&P 500 Swap UCITS ETF 1D XSXD.L | 0.00% | 104.4K | 0.07% |
| 5 | Xtrackers MSCI World Swap UCITS ETF 1C XMWD.L | 0.00% | 98.7K | 0.45% |
| 6 | Xtrackers - Xtrackers MSCI World Swap UCITS ETF 4C - EUR Hedged XWEH.DE | 0.00% | 98.6K | 0.39% |
Insider Activity
Insider Activity — Latest Quarter
Ratio by transactions
0.00
Bearish
Buys
0
Sells
0
Shares acquired
—
Shares disposed
—
Cash buys
—
Cash sales
—
Net activity
+0
Insider buys vs sells (history)
From
To
Recent insider transactions
From
To
| Date | Person | Role | Transaction | A/D | Security | Shares | Price | Value | Owned after | D/I | Filing |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026-03-18 | de Boer Daniel Anton | Director / Officer | — | — | Share Option (Right to Buy) | 1,200,000 | 0.66 | 792.0K | 0 | D | ↗ |
| 2026-03-18 | Valerio Domenico | Director | — | — | Ordinary Shares | 0 | 0.00 | — | 304,963 | I | ↗ |
| 2026-03-18 | Shannon James Samuel | Director | — | — | Share Option (Right to Buy) | 25,192 | 2.02 | 50.9K | 0 | D | ↗ |
| 2026-03-18 | Platenburg Gerardus Johannes | Director / Officer | — | — | Share Option (Right to Buy) | 186,139 | 2.02 | 376.0K | 0 | D | ↗ |
| 2026-03-18 | Maier Martin Alexander | Director | — | — | Share Option (Right to Buy) | 500 | 1.02 | 510.00 | 0 | D | ↗ |
| 2026-03-18 | Lawton Alison Frances | Director | — | — | Share Option (Right to Buy) | 27,500 | 3.30 | 90.8K | 0 | D | ↗ |
| 2026-03-18 | Hom Dennis | Officer | — | — | Share Option (Right to Buy) | 750,000 | 1.66 | 1.25M | 0 | D | ↗ |
| 2026-03-18 | HEGGIE THERESA | Director | — | — | Ordinary Shares | 0 | 0.00 | — | 43,623 | D | ↗ |
| 2026-03-18 | Filius Bart | Director | — | — | Share Option (Right to Buy) | 12,755 | 11.69 | 149.1K | 0 | D | ↗ |
| 2026-03-18 | Carreno-Gomez Begona | Director | — | — | Share Option (Right to Buy) | 3,565 | 0.95 | 3.4K | 0 | D | ↗ |
Executive team
Top executives
EBIT / Employee
-2.5K
Shares Outstanding
105.36M
Executive compensation
Executive compensation (annual)
Executive compensation not available.
CEO compensation breakdown
No CEO compensation history available.
Proxy statements
Proxy statements (DEF 14A)
No proxy statements available for this company yet.
Recent SEC filings
Executive team
| Name | Title | Compensation | Gender |
|---|---|---|---|
| Daniel Anton de Boer | Founder, CEO & Executive Director | 1M | male |
| Gerard Platenburg | Co-Founder, Chief Scientific Officer & Executive Director | 676.6K | — |
| Domenico Valerio | Founder & Independent Member of Supervisory Board | 51.8K | — |
| Sarah Cue Kiely | Vice President of Investor Relations & Corporate Communications | — | female |
| Cristina Lopez Lopez | Chief Medical Officer | — | — |
| Sheila Sponselee | Chief People & Operations Officer | — | female |
| Dennis Hom | Chief Financial Officer | — | male |
| Sandra van der Kolk | Junior Financial Controller | — | female |
ESG Rating
ESG Score History BIOTECHNOLOGY
Benchmark vs Sector
Senate Trading Activity
No Senate trading activity found for this company.
House Trading Activity
No House trading activity found for this company.
Market share among peers
Peer comparison — filtered group (TTM)
Your opinion
Share your view on this stock and instantly see how the community has voted over the last 6 months.
Community Opinion for PRQR
Short-term intention
Target Price Distribution
These are community opinions and do not constitute buy or sell advice to act on. The results shown are based on aggregated opinions and are not an investment recommendation, nor do they intend to influence any investment decision.
