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Pliant Therapeutics, Inc. (PLRX)

USD1.12 +0.03 (+2.29%)
US NASDAQ Healthcare Biotechnology
Address 260 Littlefield Avenue 94080
South San Francisco, CA, US
CEO Bernard Coulie
IPO 2020-06-03
CIK 1746473 ISIN US7291391057

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Description

Pliant Therapeutics, Inc. is a biopharmaceutical company in the clinical development stage, dedicated to discovering, advancing, and bringing to market innovative therapies for fibrotic and related diseases across the United States. Its flagship investigational product, PLN-74809, is an orally administered, small-molecule, dual-selective inhibitor targeting both avß6 and avß1 integrins, which is currently progressing through three distinct Phase 2a clinical trials. The company's pipeline also includes PLN-1474, a small-molecule selective inhibitor of avß1, which has successfully completed its Phase 1 clinical assessment for treating liver fibrosis associated with nonalcoholic steatohepatitis (NASH). Furthermore, Pliant is nurturing two additional integrin-based initiatives in preclinical development: one focused on oncology, and another involving an allosteric agonistic monoclonal antibody designed to act upon an undisclosed integrin receptor for the treatment of various muscular dystrophies, including Duchenne muscular dystrophy. Founded in 2015, Pliant Therapeutics, Inc. maintains its corporate headquarters in South San Francisco, California.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
USD1.12 +0.03 (+2.29%)
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Volume Profile
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Liquidity & share structure
Average Volume
468.2K
Beta
1.21
Float Shares
60.23M
Free Float %
97.3%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
-1.67% -5.60% -9.23% +6.31% -31.40% -3.28% -14.49% -94.72% -95.97% -94.46% -94.46%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Analyst Consensus (16 ratings, all time) Buy
Price Targets & DCF
Current price
1.12
Low 3.00 +169.1%
Consensus 3.00 +169.1%
Median 3.00 +169.1%
High 3.00 +169.1%
DCF (Unlevered) 0.27 -75.7%
DCF (Levered) 0.27 -76.1%

DCF figures are point estimates: small changes in growth or discount-rate assumptions move them materially. Read them as a reference, not a precise target.

Ratings Trend (MoM) 17% Bullish
Rating 2026-05 Change
Strong Buy 1 0
Buy 0 0
Hold 4 -1
Sell 0 0
Strong Sell 1 0
Price Target Summary
Period # Analysts Avg Target
Last Month
Last Quarter 1
3.00
+169.1%
Last Year 1
3.00
+169.1%
All Time 11
29.27
+2,525.1%
Quality scores
Altman Z-Score
-5.81
Distress
Piotroski F-Score
3 / 9
Average
MOAT Score
2 / 10
No MOAT
Composite Rating
C+
Overall Score
2 / 5
Medium
DCF Score
3 / 5
Medium
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
2 / 5
Medium
P/E Score
1 / 5
Low
P/Book Score
5 / 5
High
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
  • EPS growth Biotechnology: +29.7%
    +30.0% Q1'26: +65.2% (vs Q1'25)
  • FCF margin FCF growth · Biotechnology: +16.2%
  • EBIT margin Biotechnology: +0.0%
  • ROIC Biotechnology: -16.1%
    -774.9% Q1'26: +0.0% (vs Q1'25)
  • Share dilution Biotechnology: -3.4%
    +1.4% Q1'26: +0.9% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    -0.20× Q1'26: -0.33× (vs Q1'25)
Valuation Multiples From To
DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (1.21) × ERP
WACC = 72% × Ke + 28% × Kd (8.8%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Intrinsic value (base): 0.27 Current price: 1.12
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2020
actual
Dec 2021
actual
Dec 2022
actual
Dec 2023
actual
Dec 2024
actual
Dec 2025
actual
Dec 2026
6 Rev. Ana.
4 EPS Ana.
Dec 2027
6 Rev. Ana.
4 EPS Ana.
Dec 2028
5 Rev. Ana.
4 EPS Ana.
Dec 2029
2 Rev. Ana.
2 EPS Ana.
Dec 2030
2 Rev. Ana.
2 EPS Ana.
Revenue
41.82M
est: 39.43M (+6.0%)
7.57M
est: 7.72M (-2.0%)
9.69M
est: 8.99M (+7.7%)
1.58M
est: 248.0K (+537.1%)
est: 90.9K (-100.0%)
est: 3.33M (-100.0%)
2.50M
2.50M – 2.50M
-25.0% YoY
5.00M
5.00M – 5.00M
+100.0% YoY
25.00M
25.00M – 25.00M
+400.0% YoY
15.00M
15.00M – 15.00M
-40.0% YoY
107.50M
107.50M – 107.50M
+616.7% YoY
EBITDA
-40.34M
est: -23.38M (-72.5%)
-95.73M
est: -94.96M (-0.8%)
-118.85M
est: -103.22M (-15.1%)
-158.23M
est: -49.6K (-318,914.5%)
-205.16M
est: -18.2K (-1,128,303.3%)
-148.38M
est: -666.7K (-22,156.6%)
-500.0K
-500.0K – -500.0K
+25.0% YoY
-1,000.0K
-1,000.0K – -1,000.0K
-100.0% YoY
-5.00M
-5.00M – -5.00M
-400.0% YoY
-3.00M
-3.00M – -3.00M
+40.0% YoY
-21.50M
-21.50M – -21.50M
-616.7% YoY
EBIT
-41.65M
est: -23.63M (-76.3%)
-97.26M
est: -97.07M (-0.2%)
-122.53M
est: -105.70M (-15.9%)
-160.07M
est: -49.6K (-322,626.3%)
-207.28M
est: -18.2K (-1,139,991.3%)
-150.07M
est: -666.7K (-22,411.0%)
-500.0K
-500.0K – -500.0K
+25.0% YoY
-1,000.0K
-1,000.0K – -1,000.0K
-100.0% YoY
-5.00M
-5.00M – -5.00M
-400.0% YoY
-3.00M
-3.00M – -3.00M
+40.0% YoY
-21.50M
-21.50M – -21.50M
-616.7% YoY
Net Income
-41.53M
est: -131.15M (+68.3%)
-97.26M
est: -96.80M (-0.5%)
-123.32M
est: -144.42M (+14.6%)
-161.34M
est: -189.48M (+14.9%)
-210.30M
est: -218.38M (+3.7%)
-149.34M
est: -149.34M (+0.0%)
-94.31M
-105.95M – -73.81M
+36.9% YoY
-78.73M
-86.85M – -56.43M
+16.5% YoY
-62.91M
-111.11M – -14.71M
+20.1% YoY
-68.12M
-68.12M – -68.12M
-8.3% YoY
-48.48M
-48.48M – -48.48M
+28.8% YoY
SGA
17.27M
est: 361.53M (-95.2%)
27.56M
est: -33.40M (+182.5%)
39.95M
est: -25.65M (+255.7%)
57.93M
est: 2.30M (+2,415.5%)
59.06M
est: 844.1K (+6,895.9%)
47.22M
est: 30.95M (+52.5%)
23.21M
23.21M – 23.21M
-25.0% YoY
46.43M
46.43M – 46.43M
+100.0% YoY
232.14M
232.14M – 232.14M
+400.0% YoY
139.28M
139.28M – 139.28M
-40.0% YoY
998.19M
998.19M – 998.19M
+616.7% YoY
EPS
-1.17
est: -2.17 (+46.0%)
-2.71
est: -2.79 (+3.0%)
-2.94
est: -2.89 (-1.6%)
-2.75
est: -3.09 (+10.9%)
-3.47
est: -3.56 (+2.6%)
-2.43
est: -2.43 (-0.2%)
-1.46
-1.73 – -1.20
+39.6% YoY
-1.10
-1.42 – -0.92
+24.7% YoY
-0.97
-1.81 – -0.24
+12.4% YoY
-1.11
-1.11 – -1.11
-15.0% YoY
-0.79
-0.79 – -0.79
+28.8% YoY
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-11 C+ 2/5 3/5 1/5 1/5 2/5 1/5 5/5
2026-05-08 C+ 2/5 3/5 1/5 1/5 2/5 1/5 5/5
2026-05-07 C+ 2/5 3/5 1/5 1/5 2/5 1/5 5/5
2026-05-06 C+ 2/5 3/5 1/5 1/5 2/5 1/5 5/5
2026-05-05 C+ 2/5 3/5 1/5 1/5 2/5 1/5 5/5
2026-05-04 C+ 2/5 3/5 1/5 1/5 2/5 1/5 5/5
2026-05-01 C+ 2/5 3/5 1/5 1/5 2/5 1/5 5/5
2026-04-30 C+ 2/5 3/5 1/5 1/5 2/5 1/5 5/5
2026-04-29 C+ 2/5 3/5 1/5 1/5 2/5 1/5 5/5
2026-04-28 C+ 2/5 3/5 1/5 1/5 2/5 1/5 5/5
2026-04-27 C+ 2/5 3/5 1/5 1/5 2/5 1/5 5/5
2026-04-24 C+ 2/5 3/5 1/5 1/5 2/5 1/5 5/5
2026-04-23 C+ 2/5 3/5 1/5 1/5 2/5 1/5 5/5
2026-04-22 C+ 2/5 3/5 1/5 1/5 2/5 1/5 5/5
2026-04-21 C+ 2/5 3/5 1/5 1/5 2/5 1/5 5/5
2026-04-20 C+ 2/5 3/5 1/5 1/5 2/5 1/5 5/5
2026-04-17 C+ 2/5 3/5 1/5 1/5 2/5 1/5 5/5
2026-04-16 C+ 2/5 3/5 1/5 1/5 2/5 1/5 5/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
-98.70M
OE per share TTM
-1.61
Owner's Yield
-133.08%
Maintenance CapEx ratio
Maint CapEx / Avg PPE
78.0%

Ownership Overview

Ownership breakdown
At a glance
Institutional holders
7
Total invested
1.76M
Insider transactions (90d)
4
Beneficial owners (>5%)
32
Beneficial owners (>5%)
# Reporting person Amount owned % of class Sole voting Shared voting Sole dispositive Shared dispositive Type Citizenship Filing date SEC filing
1 Kevin P. Starr 5.84M 16.50% 5.84M 5.84M IN Delaware 2021-02-16
2 Mark Levin 5.84M 16.50% 5.84M 5.84M IN Delaware 2021-02-16
3 Robert I. Tepper 5.84M 16.50% 5.84M 5.84M IN Delaware 2021-02-16
4 TRV GP III, LLC 5.84M 16.50% 5.84M 5.84M OO Delaware 2021-02-16
5 Third Rock Ventures GP III, L.P. 5.84M 16.50% 5.84M 5.84M PN Delaware 2021-02-16
6 Third Rock Ventures III, L.P. 5.84M 16.50% 5.84M 5.84M PN Delaware 2021-02-16
7 Abigail P. Johnson 5.33M 15.00% 5.33M IN Delaware 2020-07-10
8 FMR LLC 5.33M 15.00% 697.9K 5.33M HC Delaware 2020-07-10
9 (1) BlackRock, Inc. 4.80M 8.00% 4.74M 4.80M HC Delaware 2024-01-25
10 52-0556948 3.79M 6.30% 791.2K 3.79M IA Maryland 2024-02-14
11 Mathew P. Arens 3.68M 6.14% 2.0K 3.68M 2.0K IN Delaware 2024-02-14
12 First Light Asset Management, LLC 3.63M 6.07% 3.63M IA Delaware 2024-02-14
13 Benjamin Alexander Smith 3.58M 5.98% 3.58M IN United States 2024-02-08
14 Janaka Sheehan Maduraperuma 3.58M 5.98% 3.58M IN United Kingdom 2024-02-08
15 Laurion Capital Management LP 3.58M 5.98% 3.58M IA, PN Delaware 2024-02-08
16 Jeremy C. Green 3.20M 5.30% 3.20M 3.20M HC, IN Delaware 2024-11-14
17 Redmile Group, LLC 3.20M 5.30% 3.20M 3.20M IA, OO Delaware 2024-11-14
18 David Kroin 3.10M 5.27% 3.10M HC, IN Delaware 2023-03-20
19 Deep Track Biotechnology Master Fund, Ltd. 3.10M 5.27% 3.10M CO Delaware 2023-03-20
20 Deep Track Capital, LP 3.10M 5.27% 3.10M IA, OO Delaware 2023-03-20
21 Blue Owl Capital Holdings LP 3.00M 5.02% 3.00M 3.00M PN Delaware 2024-02-14
22 CHI Advisors LLC 2.35M 6.60% 2.35M 2.35M IA Delaware 2021-03-02
23 2. 2.15M 6.10% 2.15M 2.15M CO 2020-06-15
24 Novartis AG 2.15M 4.40% 2.15M 2.15M HC, CO Delaware 2022-08-31
25 Novartis Institutes for BioMedical Research, Inc. 2.15M 4.40% 2.15M 2.15M CO Delaware 2022-08-31
26 TRV GP IV, LLC 2.13M 6.00% 2.13M 2.13M OO Delaware 2021-02-16
27 Third Rock Ventures GP IV, L.P. 2.13M 6.00% 2.13M 2.13M PN Delaware 2021-02-16
28 Third Rock Ventures IV, L.P. 2.13M 6.00% 2.13M 2.13M PN Delaware 2021-02-16
29 Redmile Biopharma Investments II, L.P. 1.91M 5.30% 1.91M 1.91M PN 2022-02-14
30 Eventide Asset Management, LLC 42.5K 0.10% 42.5K 42.5K IA Delaware 2022-02-14
31 Finny Kuruvilla, M.D. Ph. D. 42.5K 0.10% 42.5K HC, IN United States 2022-02-14
32 Robin C. John 42.5K 0.10% 42.5K HC, IN United States 2022-02-14

Institutional Activity (13F)

Institutional ownership trend From To
13F snapshot — 2026 Q1
Investors holding
7
-92 vs prev Q
New positions
1
Closed positions
89
Increased
3
Reduced
1
Put/Call ratio
0.00
Calls held
Puts held
Top institutional holders
# Investor Shares / Δ Mkt value / Δ Own% / Δ Weight% / Δ Avg px / Perf. Hold / Status
1 NANO CAP NEW MILLENNIUM GROWTH FUND L P 235.0K +235.0K (+100.0%) 286.70M +286.7M (+100.0%) 0.38% +0.383 pp 0.24% +0.245 pp USD1.22 +0.0% 1 qtrs NEW
2 TANG CAPITAL MANAGEMENT LLC 6.14M +139.7K (+2.3%) 7.49M -1.4M (-15.6%) 10.00% +0.224 pp 0.37% +0.028 pp USD1.35 -9.6% 4 qtrs
3 BLUE OWL CAPITAL HOLDINGS LP 2.97M +— (+0.0%) 3.62M -772.0K (-17.6%) 4.84% -0.002 pp 0.27% -1.093 pp USD16.98 -92.8% 9 qtrs
4 VANGUARD GROUP INC 2.82M +42.3K (+1.5%) 3.44M -670.1K (-16.3%) 4.59% +0.067 pp 0.00% +0.000 pp USD21.52 -94.3% 23 qtrs
5 CITADEL ADVISORS LLC 2.58M +243.9K (+10.4%) 3.15M -310.7K (-9.0%) 4.21% +0.396 pp 0.00% 0.000 pp USD1.17 +4.3% 23 qtrs
6 ACADIAN ASSET MANAGEMENT LLC 2.36M -4.9K (-0.2%) 2.88M -622.0K (-17.8%) 3.85% -0.009 pp 0.00% -0.001 pp USD1.36 -10.3% 4 qtrs
7 WOODLINE PARTNERS LP 2.03M -2.5M (-55.0%) 2.47M -4.2M (-62.9%) 3.30% -4.039 pp 0.01% -0.022 pp USD1.82 -33.0% 11 qtrs
8 MONACO ASSET MANAGEMENT SAM 1.94M +1.1M (+135.7%) 2.37M +1.1M (+94.3%) 3.16% +1.817 pp 0.41% +0.336 pp USD1.21 +0.8% 3 qtrs
9 REDMILE GROUP, LLC 1.62M +24.5K (+1.5%) 1.97M -383.9K (-16.3%) 2.63% +0.039 pp 0.15% -0.084 pp USD25.95 -95.3% 23 qtrs
10 PROSIGHT MANAGEMENT, LP 1.56M +1.5M (+7,493.8%) 1.90M +1.9M (+6,159.7%) 2.53% +2.500 pp 0.39% +0.385 pp USD1.22 +0.0% 4 qtrs
11 BML CAPITAL MANAGEMENT, LLC 1.55M +1.5M (+100.0%) 1.89M +1.9M (+100.0%) 2.52% +2.518 pp 1.63% +1.631 pp USD1.22 +0.0% 1 qtrs NEW
12 TWO SIGMA ADVISERS, LP 1.25M +173.1K (+16.1%) 1.52M -67.7K (-4.3%) 2.03% +0.281 pp 0.00% 0.000 pp USD3.05 -60.0% 17 qtrs
13 JPMORGAN CHASE & CO 1.21M -917.6K (-43.1%) 1.48M -1.7M (-53.1%) 1.98% -1.496 pp 0.00% 0.000 pp USD2.46 -50.4% 22 qtrs
14 MARSHALL WACE, LLP 1.08M +780.7K (+260.7%) 1.32M +874.6K (+197.3%) 1.76% +1.271 pp 0.00% +0.001 pp USD1.29 -5.4% 5 qtrs
15 BLACKROCK, INC. 1.07M -347.6K (-24.5%) 1.31M -793.5K (-37.7%) 1.75% -0.567 pp 0.00% +0.000 pp USD11.09 -89.0% 6 qtrs
16 UBS GROUP AG 1.06M -259.4K (-19.6%) 1.30M -660.2K (-33.7%) 1.73% -0.423 pp 0.00% 0.000 pp USD4.34 -71.9% 22 qtrs
17 RENAISSANCE TECHNOLOGIES LLC 1.05M +34.0K (+3.4%) 1.28M -221.6K (-14.8%) 1.70% +0.055 pp 0.00% +0.000 pp USD1.72 -29.1% 8 qtrs
18 CENTIVA CAPITAL, LP 1.00M +1.0M (+100.0%) 1.22M +1.2M (+100.0%) 1.63% +1.629 pp 0.01% +0.010 pp USD1.22 +0.0% 1 qtrs NEW
19 TWO SIGMA INVESTMENTS, LP 953.3K +170.0K (+21.7%) 1.16M +3.8K (+0.3%) 1.55% +0.277 pp 0.00% 0.000 pp USD2.54 -52.0% 17 qtrs
20 PEAPOD LANE CAPITAL LLC 886.4K -210.7K (-19.2%) 1.08M -542.2K (-33.4%) 1.44% -0.344 pp 0.92% -0.532 pp USD1.33 -8.3% 4 qtrs
21 EVERSEPT PARTNERS, LP 842.0K +17.4K (+2.1%) 1.03M -193.1K (-15.8%) 1.37% +0.028 pp 0.05% -0.032 pp USD1.47 -17.0% 2 qtrs
22 BANK OF AMERICA CORP /DE/ 711.8K +3.7K (+0.5%) 868.4K -179.6K (-17.1%) 1.16% +0.006 pp 0.00% +0.000 pp USD2.58 -52.7% 22 qtrs
23 JANE STREET GROUP, LLC 653.8K +273.4K (+71.9%) 797.6K +234.7K (+41.7%) 1.06% +0.445 pp 0.00% +0.000 pp USD4.09 -70.2% 13 qtrs
24 GSA CAPITAL PARTNERS LLP 623.7K +462.8K (+287.7%) 761.0K +523.0K (+219.7%) 1.02% +0.754 pp 0.07% +0.046 pp USD1.28 -4.7% 4 qtrs
25 GEODE CAPITAL MANAGEMENT, LLC 592.7K +5.3K (+0.9%) 723.4K -146.4K (-16.8%) 0.97% +0.008 pp 0.00% +0.000 pp USD18.70 -93.5% 23 qtrs
26 JACOBS LEVY EQUITY MANAGEMENT, INC 556.9K +189.8K (+51.7%) 679.5K +136.1K (+25.1%) 0.91% +0.309 pp 0.00% +0.001 pp USD1.39 -12.2% 2 qtrs
27 MORGAN STANLEY 549.0K -3.0M (-84.3%) 669.7K -4.5M (-87.1%) 0.89% -4.820 pp 0.00% 0.000 pp USD4.10 -70.2% 23 qtrs
28 XTX TOPCO LTD 545.0K +78.0K (+16.7%) 664.9K -26.2K (-3.8%) 0.89% +0.127 pp 0.02% -0.018 pp USD1.34 -9.0% 4 qtrs
29 BESSEMER GROUP INC 532.1K +— (+0.0%) 649.0K -138.0K (-17.5%) 0.87% 0.000 pp 0.00% 0.000 pp USD31.41 -96.1% 23 qtrs
30 DEKABANK DEUTSCHE GIROZENTRALE 40.0K +— (+0.0%) 633.0K +576.0K (+1,010.5%) 0.07% +0.000 pp 0.00% +0.001 pp USD24.48 -95.0% 12 qtrs
31 MILLENNIUM MANAGEMENT LLC 408.8K -128.5K (-23.9%) 498.8K -296.5K (-37.3%) 0.67% -0.210 pp 0.00% 0.000 pp USD1.16 +5.2% 3 qtrs
32 CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD. 372.0K +347.6K (+1,428.1%) 453.8K +417.8K (+1,159.7%) 0.61% +0.566 pp 0.00% +0.001 pp USD1.24 -1.6% 2 qtrs
33 BRIDGEWAY CAPITAL MANAGEMENT, LLC 321.5K +239.2K (+290.7%) 392.3K +270.5K (+222.0%) 0.52% +0.390 pp 0.01% +0.006 pp USD1.20 +1.7% 3 qtrs
34 TORNO CAPITAL, LLC 320.0K +189.1K (+144.4%) 390.4K +196.6K (+101.5%) 0.52% +0.308 pp 0.09% +0.071 pp USD1.33 -8.3% 2 qtrs
35 SEI INVESTMENTS CO 297.3K +— (+0.0%) 362.7K -77.3K (-17.6%) 0.48% 0.000 pp 0.00% 0.000 pp USD1.32 -7.6% 4 qtrs
36 ARROWMARK COLORADO HOLDINGS LLC 281.2K +— (+0.0%) 343.1K -73.1K (-17.6%) 0.46% 0.000 pp 0.01% 0.000 pp USD18.12 -93.3% 11 qtrs
37 GOLDMAN SACHS GROUP INC 276.9K -278.2K (-50.1%) 337.8K -483.7K (-58.9%) 0.45% -0.453 pp 0.00% 0.000 pp USD11.30 -89.2% 23 qtrs
38 276.5K +276.5K (+100.0%) 337.3K +337.3K (+100.0%) 0.45% +0.450 pp 0.26% +0.257 pp USD1.22 +0.0% 1 qtrs NEW
39 LAURION CAPITAL MANAGEMENT LP 257.4K +257.4K (+100.0%) 314.0K +314.0K (+100.0%) 0.42% +0.419 pp 0.01% +0.012 pp USD1.22 +0.0% 1 qtrs NEW
40 STATE STREET CORP 253.4K -416.0 (-0.2%) 309.2K -66.5K (-17.7%) 0.41% -0.001 pp 0.00% +0.000 pp USD18.76 -93.5% 22 qtrs
41 STONEPINE CAPITAL MANAGEMENT, LLC 230.1K -59.2K (-20.5%) 280.7K -147.4K (-34.4%) 0.37% -0.097 pp 0.20% -0.143 pp USD1.48 -17.6% 2 qtrs
42 RANGELEY CAPITAL, LLC 225.0K +164.8K (+273.6%) 274.5K +185.4K (+208.0%) 0.37% +0.268 pp 0.23% +0.151 pp USD1.25 -2.4% 4 qtrs
43 HIGHMARK WEALTH MANAGEMENT LLC 170.9K -48.1K (-22.0%) 208.5K -115.6K (-35.7%) 0.28% -0.078 pp 0.09% -0.058 pp USD5.39 -77.4% 9 qtrs
44 RICE HALL JAMES & ASSOCIATES, LLC 147.7K +2.9K (+2.0%) 180.2K -34.2K (-15.9%) 0.24% +0.005 pp 0.01% -0.002 pp USD10.29 -88.1% 7 qtrs
45 DIADEMA PARTNERS LP 144.9K +144.9K (+100.0%) 176.8K +176.8K (+100.0%) 0.24% +0.236 pp 0.03% +0.031 pp USD1.22 +0.0% 1 qtrs NEW
46 NORTHERN TRUST CORP 123.3K -13.2K (-9.7%) 150.4K -51.6K (-25.6%) 0.20% -0.022 pp 0.00% +0.000 pp USD18.50 -93.4% 22 qtrs
47 DIMENSIONAL FUND ADVISORS LP 121.8K -29.9K (-19.7%) 148.5K -76.0K (-33.9%) 0.20% -0.049 pp 0.00% +0.000 pp USD14.72 -91.7% 16 qtrs
48 SUSQUEHANNA INTERNATIONAL GROUP, LLP 115.3K +58.8K (+104.1%) 140.7K +57.0K (+68.2%) 0.19% +0.096 pp 0.00% +0.000 pp USD5.67 -78.5% 17 qtrs
49 ADVISOR GROUP HOLDINGS, INC. 115.0K -10.4K (-8.3%) 140.3K -45.4K (-24.4%) 0.19% -0.017 pp 0.00% 0.000 pp USD1.95 -37.4% 14 qtrs
50 INVESCO LTD. 113.9K +6.8K (+6.4%) 139.0K -19.5K (-12.3%) 0.19% +0.011 pp 0.00% +0.000 pp USD7.81 -84.4% 11 qtrs
51 HENNION & WALSH ASSET MANAGEMENT, INC. 113.4K +15.3K (+15.7%) 138.3K -6.8K (-4.7%) 0.18% +0.025 pp 0.00% -0.001 pp USD9.93 -87.7% 7 qtrs
52 BOND & DEVICK FINANCIAL NETWORK, INC. 100.2K +— (+0.0%) 122.2K -26.0K (-17.6%) 0.16% 0.000 pp 0.03% -0.010 pp USD29.12 -95.8% 19 qtrs
53 SQUAREPOINT OPS LLC 99.0K +65.2K (+192.6%) 120.8K +70.7K (+141.2%) 0.16% +0.106 pp 0.00% +0.000 pp USD1.75 -30.3% 7 qtrs
54 QUADRATURE CAPITAL LTD 97.9K +60.3K (+160.4%) 119.4K +64.0K (+115.4%) 0.16% +0.098 pp 0.00% +0.001 pp USD1.27 -3.9% 4 qtrs
55 KOTLER KEVIN 93.0K +93.0K (+100.0%) 113.5K +113.5K (+100.0%) 0.15% +0.151 pp 0.03% +0.027 pp USD1.22 +0.0% 1 qtrs NEW
56 ALGERT GLOBAL LLC 84.5K -19.9K (-19.1%) 103.0K -51.0K (-33.1%) 0.14% -0.033 pp 0.00% -0.001 pp USD10.54 -88.4% 12 qtrs
57 ADAR1 CAPITAL MANAGEMENT, LLC 73.8K +73.8K (+100.0%) 90.1K +90.1K (+100.0%) 0.12% +0.120 pp 0.01% +0.007 pp USD1.22 +0.0% 7 qtrs
58 CANADA PENSION PLAN INVESTMENT BOARD 61.4K +61.4K (+100.0%) 74.9K +74.9K (+100.0%) 0.10% +0.100 pp 0.00% +0.000 pp USD1.22 +0.0% 3 qtrs
59 FEDERATED HERMES, INC. 59.5K +4.2K (+7.6%) 72.6K -9.3K (-11.3%) 0.10% +0.007 pp 0.00% +0.000 pp USD1.70 -28.2% 6 qtrs
60 POINT72 ASSET MANAGEMENT, L.P. 46.5K -4.3M (-98.9%) 56.8K -6.4M (-99.1%) 0.08% -6.992 pp 0.00% -0.011 pp USD1.48 -17.6% 2 qtrs
61 SIMPLEX TRADING, LLC 45.9K +32.9K (+253.5%) 56.0K +37.0K (+194.8%) 0.07% +0.054 pp 0.00% +0.000 pp USD2.48 -50.8% 15 qtrs
62 PERSISTENT ASSET PARTNERS LTD 38.8K +38.8K (+100.0%) 47.4K +47.4K (+100.0%) 0.06% +0.063 pp 0.02% +0.021 pp USD1.22 +0.0% 1 qtrs NEW
63 HRT FINANCIAL LP 32.2K +32.2K (+100.0%) 39.0K +39.0K (+100.0%) 0.05% +0.052 pp 0.00% +0.000 pp USD1.22 +0.0% 3 qtrs
64 ENGINEERS GATE MANAGER LP 30.5K +7.1K (+30.0%) 37.3K +2.5K (+7.2%) 0.05% +0.012 pp 0.00% +0.000 pp USD1.23 -0.8% 6 qtrs
65 TUDOR INVESTMENT CORP ET AL 29.7K +— (+0.0%) 36.3K -7.7K (-17.6%) 0.05% +0.000 pp 0.00% +0.000 pp USD1.35 -9.6% 8 qtrs
66 VANGUARD PERSONALIZED INDEXING MANAGEMENT, LLC 26.2K -8.5K (-24.5%) 32.0K -19.4K (-37.7%) 0.04% -0.014 pp 0.00% 0.000 pp USD1.25 -2.4% 4 qtrs
67 BLACKSTONE INC. 22.2K +— (+0.0%) 27.1K -5.8K (-17.6%) 0.04% +0.000 pp 0.00% +0.000 pp USD19.71 -93.8% 14 qtrs
68 BRONTE CAPITAL MANAGEMENT PTY LTD. 18.6K +18.6K (+100.0%) 22.7K +22.7K (+100.0%) 0.03% +0.030 pp 0.00% +0.002 pp USD1.22 +0.0% 1 qtrs NEW
69 UNIVERSAL- BETEILIGUNGS- UND SERVICEGESELLSCHAFT MBH 18.1K +— (+0.0%) 22.0K -4.7K (-17.6%) 0.03% +0.000 pp 0.00% +0.000 pp USD1.35 -9.6% 4 qtrs
70 BANK OF NEW YORK MELLON CORP 15.8K -109.0 (-0.7%) 19.3K -4.3K (-18.1%) 0.03% 0.000 pp 0.00% +0.000 pp USD17.81 -93.1% 23 qtrs
71 GROUP ONE TRADING, L.P. 15.8K +12.7K (+405.9%) 19.3K +14.6K (+317.1%) 0.03% +0.021 pp 0.00% +0.000 pp USD4.35 -72.0% 12 qtrs
72 QUBE RESEARCH & TECHNOLOGIES LTD 15.4K -34.1K (-68.8%) 18.8K -54.5K (-74.3%) 0.03% -0.056 pp 0.00% 0.000 pp USD1.16 +5.2% 3 qtrs
73 SG AMERICAS SECURITIES, LLC 12.3K -4.5K (-26.9%) 15.0K -10.0K (-40.0%) 0.02% -0.007 pp 0.00% 0.000 pp USD9.28 -86.9% 8 qtrs
74 QUEST PARTNERS LLC 11.7K +— (+0.0%) 14.3K -3.0K (-17.6%) 0.02% +0.000 pp 0.00% 0.000 pp USD8.17 -85.1% 9 qtrs
75 FIDUCIARY TRUST CO 11.6K +— (+0.0%) 14.2K -3.0K (-17.6%) 0.02% +0.000 pp 0.00% +0.000 pp USD18.95 -93.6% 13 qtrs
76 BARCLAYS PLC 10.6K -410.9K (-97.5%) 12.9K -4.7M (-99.7%) 0.02% -0.669 pp 0.00% -0.001 pp USD1.94 -37.1% 16 qtrs
77 RHUMBLINE ADVISERS 2.4K +— (+0.0%) 2.9K -618.0 (-17.6%) 0.00% +0.000 pp 0.00% +0.000 pp USD16.97 -92.8% 11 qtrs
78 FMR LLC 1.9K -3.0K (-61.1%) 2.4K -5.0K (-67.9%) 0.00% -0.005 pp 0.00% +0.000 pp USD27.20 -95.5% 23 qtrs
79 ROYAL BANK OF CANADA 1.2K -15.0K (-92.7%) 2.0K -22.0K (-91.7%) 0.00% -0.024 pp 0.00% +0.000 pp USD5.81 -79.0% 21 qtrs
80 FORTITUDE FAMILY OFFICE, LLC 1.3K +— (+0.0%) 1.6K -332.0 (-17.6%) 0.00% +0.000 pp 0.00% 0.000 pp USD1.48 -17.6% 2 qtrs
81 PNC FINANCIAL SERVICES GROUP, INC. 978.00 -6.0 (-0.6%) 1.2K -263.0 (-18.1%) 0.00% +0.000 pp 0.00% +0.000 pp USD2.40 -49.2% 12 qtrs
82 ROCKEFELLER CAPITAL MANAGEMENT L.P. 660.00 -425.0 (-39.2%) 805.00 -801.0 (-49.9%) 0.00% -0.001 pp 0.00% +0.000 pp USD1.48 -17.6% 2 qtrs
83 BNP PARIBAS ARBITRAGE, SNC 657.00 -181.7K (-99.6%) 802.00 -269.1K (-99.7%) 0.00% -0.296 pp 0.00% 0.000 pp USD1.78 -31.5% 5 qtrs
84 RUSSELL INVESTMENTS GROUP, LTD. 542.00 -864.0 (-61.5%) 661.00 -1.4K (-68.2%) 0.00% -0.001 pp 0.00% +0.000 pp USD1.97 -38.1% 19 qtrs
85 BARE FINANCIAL SERVICES, INC 413.00 +413.0 (+100.0%) 504.00 +504.0 (+100.0%) 0.00% +0.001 pp 0.00% +0.000 pp USD1.22 +0.0% 1 qtrs NEW
86 MAI CAPITAL MANAGEMENT 400.00 +— (+0.0%) 488.00 -104.0 (-17.6%) 0.00% +0.000 pp 0.00% +0.000 pp USD13.17 -90.7% 5 qtrs
87 SBI SECURITIES CO., LTD. 320.00 +— (+0.0%) 390.00 -84.0 (-17.7%) 0.00% +0.000 pp 0.00% +0.000 pp USD4.68 -73.9% 5 qtrs
88 TRUVESTMENTS CAPITAL LLC 50.00 +— (+0.0%) 61.00 -13.0 (-17.6%) 0.00% +0.000 pp 0.00% +0.000 pp USD11.20 -89.1% 12 qtrs
89 WELLS FARGO & COMPANY/MN 50.00 +— (+0.0%) 61.00 -13.0 (-17.6%) 0.00% +0.000 pp 0.00% +0.000 pp USD16.44 -92.6% 22 qtrs
90 ZURCHER KANTONALBANK (ZURICH CANTONALBANK) 36.00 -570.0 (-94.1%) 44.00 -853.0 (-95.1%) 0.00% -0.001 pp 0.00% +0.000 pp USD16.06 -92.4% 13 qtrs
91 COMERICA BANK 6.00 -8.0 (-57.1%) 7.00 -14.0 (-66.7%) 0.00% +0.000 pp 0.00% +0.000 pp USD17.17 -92.9% 10 qtrs
92 FARTHER FINANCE ADVISORS, LLC 5.00 +— (+0.0%) 6.00 -1.0 (-14.3%) 0.00% +0.000 pp 0.00% +0.000 pp USD18.00 -93.2% 9 qtrs
93 GLOBAL RETIREMENT PARTNERS, LLC 4.00 +— (+0.0%) 5.00 -1.0 (-16.7%) 0.00% +0.000 pp 0.00% +0.000 pp USD1.00 +22.0% 3 qtrs
94 CAITONG INTERNATIONAL ASSET MANAGEMENT CO., LTD 1.00 -2.0K (-100.0%) 1.00 -3.0K (-100.0%) 0.00% -0.003 pp 0.00% -0.002 pp USD1.00 +22.0% 3 qtrs
95 GREAT POINT PARTNERS LLC -850.0K (-100.0%) -1.3M (-100.0%) 0.00% -1.385 pp 0.00% -0.519 pp USD 15 qtrs SOLD
Ownership breakdown by holder

ETF Ownership

Top ETFs holding this stock Held by 14 ETFs in our universe
# ETF Weight Est. AUM exposure TER
1 iShares Micro-Cap ETF IWC 0.02% 231.4K 0.60%
2 Invesco RAFI US 1500 Small-Mid ETF PRFZ 0.00% 116.6K 0.34%
3 Vanguard Health Care ETF VHT 0.00% 193.1K 0.09%
4 Vanguard Extended Market ETF VXF 0.00% 758.4K 0.05%
5 Vanguard U.S. Total Market Index ETF (CAD-hedged) VUS.TO 0.00% 945.84 0.17%
6 Vanguard U.S. Total Market Shares Index ETF VTS.AX 0.00% 4.7K 0.03%
7 Vanguard U.S. Total Market Index ETF VUN.TO 0.00% 12.8K 0.17%
8 Vanguard Total Stock Market ETF VTI 0.00% 2.19M 0.03%
9 Vanguard All-Equity ETF Portfolio VEQT.TO 0.00% 4.8K 0.22%
10 Vanguard Growth ETF Portfolio VGRO.TO 0.00% 2.6K 0.22%

Insider Activity

Insider Activity — Latest Quarter
Ratio by transactions
1.00
Neutral
Ratio by volume
1.00
Neutral
Buys
20
Sells
20
Shares acquired
3.02M
Shares disposed
3.02M
Cash buys
Cash sales
Net activity
+0
Insider buys vs sells (history) From To
Recent insider transactions From To
Date Person Role Transaction A/D Security Shares Price Value Owned after D/I Filing
2026-04-17 Kuo Minnie Officer A-Award A Stock Option (Right to Buy) 150,000 1.33 199.5K 150,000 D
2026-04-17 Cummings Keith Lamont Officer D-Return D Stock Option (Right to Buy) 18,198 6.22 113.2K 0 D
2026-04-17 Coulie Bernard Director / Officer A-Award A Stock Option (Right to Buy) 440,000 1.33 585.2K 440,000 D
2026-04-17 Cheung Lily Officer A-Award A Stock Option (Right to Buy) 123,000 1.33 163.6K 123,000 D
2026-01-22 Kuo Minnie Officer A-Award A Stock Option (Right to Buy) 300,000 1.30 390.0K 300,000 D
2026-01-22 Cummings Keith Lamont Officer A-Award A Stock Option (Right to Buy) 400,000 1.30 520.0K 400,000 D
2026-01-22 Coulie Bernard Director / Officer A-Award A Stock Option (Right to Buy) 1,230,000 1.30 1.60M 1,230,000 D
2026-01-22 Cheung Lily Officer A-Award A Stock Option (Right to Buy) 300,000 1.30 390.0K 300,000 D
2026-01-20 Kuo Minnie Officer S-Sale D Common Stock 6,917 1.28 8.9K 37,806 D
2026-01-20 Cummings Keith Lamont Officer S-Sale D Common Stock 24,002 1.28 30.7K 297,214 D
2026-01-20 Coulie Bernard Director / Officer S-Sale D Common Stock 89,375 1.28 114.4K 505,601 D
2026-01-20 Cheung Lily Officer S-Sale D Common Stock 7,534 1.28 9.6K 44,847 D
2025-12-10 Kuo Minnie Officer Common Stock 0 0.00 44,723 D
2025-06-05 PYOTT DAVID E I Director A-Award A Common Stock (Right to Buy) 30,000 1.61 48.3K 30,000 D
2025-06-05 MCCOURT Thomas A Director A-Award A Common Stock (Right to Buy) 30,000 1.61 48.3K 30,000 D
2025-06-05 Krognes Steve E. Director A-Award A Common Stock (Right to Buy) 30,000 1.61 48.3K 30,000 D
2025-06-05 Knobil Katharine Director A-Award A Common Stock (Right to Buy) 30,000 1.61 48.3K 30,000 D
2025-06-05 Huh Hoyoung Director A-Award A Common Stock (Right to Buy) 30,000 1.61 48.3K 30,000 D
2025-06-05 Curnutte John T Director A-Award A Common Stock (Right to Buy) 30,000 1.61 48.3K 30,000 D
2025-06-05 Cline Darren S Director A-Award A Common Stock (Right to Buy) 30,000 1.61 48.3K 30,000 D
2025-06-05 CROWELL GAYLE A Director A-Award A Common Stock (Right to Buy) 30,000 1.61 48.3K 30,000 D
2025-06-05 Bruhn Suzanne Louise Director A-Award A Common Stock (Right to Buy) 30,000 1.61 48.3K 30,000 D
2025-01-23 Ouimette Mike Officer A-Award A Stock Option (Right to Buy) 70,000 11.14 779.8K 70,000 D
2025-01-23 Lefebvre Eric Officer A-Award A Stock Option (Right to Buy) 91,300 11.14 1.02M 91,300 D
2025-01-23 Hull Hans Officer A-Award A Stock Option (Right to Buy) 80,300 11.14 894.5K 80,300 D
2025-01-23 Cummings Keith Lamont Officer A-Award A Stock Option (Right to Buy) 113,300 11.14 1.26M 113,300 D
2025-01-23 Coulie Bernard Director / Officer A-Award A Stock Option (Right to Buy) 325,000 11.14 3.62M 325,000 D
2025-01-23 Cheung Lily Officer A-Award A Common Stock 25,875 0.00 50,425 D
2025-01-22 Ouimette Mike Officer S-Sale D Common Stock 10,230 10.99 112.5K 70,544 D
2025-01-17 Ouimette Mike Officer S-Sale D Common Stock 13,270 11.20 148.6K 80,774 D
2025-01-17 Lefebvre Eric Officer S-Sale D Common Stock 18,478 11.20 207.0K 194,574 D
2025-01-17 Hull Hans Officer S-Sale D Common Stock 15,936 11.20 178.5K 211,558 D
2025-01-17 Cummings Keith Lamont Officer S-Sale D Common Stock 20,148 11.20 225.7K 262,608 D
2025-01-17 Coulie Bernard Director / Officer S-Sale D Common Stock 52,419 11.20 587.2K 430,517 D
2025-01-17 Cheung Lily Officer S-Sale D Common Stock 3,740 11.20 41.9K 24,550 D
2024-07-10 Ouimette Mike Officer S-Sale D Common Stock 7,656 11.56 88.5K 94,044
2024-07-10 Lefebvre Eric Officer S-Sale D Common Stock 12,319 11.56 142.4K 213,052
2024-07-10 Hull Hans Officer S-Sale D Common Stock 9,900 11.56 114.4K 227,494
2024-07-10 Cummings Keith Lamont Officer S-Sale D Common Stock 10,911 11.56 126.1K 282,115
2024-07-10 Coulie Bernard Director / Officer S-Sale D Common Stock 38,710 11.56 447.5K 482,936
2024-07-09 Ouimette Mike Officer A-Award A Common Stock 14,954 0.00 101,700
2024-07-09 Lefebvre Eric Officer A-Award A Common Stock 24,063 0.00 225,371
2024-07-09 Hull Hans Officer A-Award A Common Stock 19,337 0.00 237,394
2024-07-09 Cummings Keith Lamont Officer A-Award A Common Stock 21,313 0.00 293,026
2024-07-09 Coulie Bernard Director / Officer A-Award A Common Stock 75,625 0.00 521,646
2024-06-13 Shah Smital Director A-Award A Common Stock (Right to Buy) 26,764 13.06 349.5K 26,764
2024-06-13 PYOTT DAVID E I Director A-Award A Common Stock (Right to Buy) 26,764 13.06 349.5K 26,764
2024-06-13 MCCOURT Thomas A Director A-Award A Common Stock (Right to Buy) 26,764 13.06 349.5K 26,764
2024-06-13 Krognes Steve E. Director 0 0.00 0
2024-06-13 Knobil Katharine Director A-Award A Common Stock (Right to Buy) 26,764 13.06 349.5K 26,764
2024-06-13 Huh Hoyoung Director A-Award A Common Stock (Right to Buy) 26,764 13.06 349.5K 26,764
2024-06-13 Curnutte John T Director A-Award A Common Stock (Right to Buy) 26,764 13.06 349.5K 26,764
2024-06-13 Cline Darren S Director A-Award A Common Stock (Right to Buy) 26,764 13.06 349.5K 26,764
2024-06-13 CROWELL GAYLE A Director A-Award A Common Stock (Right to Buy) 26,764 13.06 349.5K 26,764
2024-06-13 Bruhn Suzanne Louise Director A-Award A Common Stock (Right to Buy) 26,764 13.06 349.5K 26,764
2024-05-02 Cummings Keith Lamont Officer M-Exempt A Common Stock 21,000 2.08 43.7K 271,713
2024-01-23 Ouimette Mike Officer A-Award A Stock Option (Right to Buy) 63,000 17.44 1.10M 63,000
2024-01-23 Lefebvre Eric Officer A-Award A Stock Option (Right to Buy) 85,800 17.44 1.50M 85,800
2024-01-23 Hull Hans Officer A-Award A Common Stock 31,500 0.00 216,569
2024-01-23 Cummings Keith Lamont Officer A-Award A Common Stock 55,250 0.00 249,855
2024-01-23 Coulie Bernard Director / Officer A-Award A Stock Option (Right to Buy) 256,300 17.44 4.47M 256,300
2024-01-23 Cheung Lily Officer A-Award A Common Stock 26,000 0.00 26,795
2024-01-17 Ouimette Mike Officer S-Sale D Common Stock 5,197 17.23 89.5K 55,246
2024-01-17 Lefebvre Eric Officer S-Sale D Common Stock 10,295 17.23 177.4K 156,920
2024-01-17 Hull Hans Officer S-Sale D Common Stock 9,786 17.23 168.6K 185,069
2024-01-17 Cummings Keith Lamont Officer S-Sale D Common Stock 9,781 17.23 168.5K 194,605
2024-01-17 Coulie Bernard Director / Officer S-Sale D Common Stock 25,721 17.23 443.2K 316,382
2023-08-04 Hull Hans Officer M-Exempt D Common Stock (Right to Buy) 8,791 2.08 18.3K 31,367
2023-08-03 Hull Hans Officer M-Exempt A Common Stock 1,800 2.08 3.7K 207,914
2023-07-20 Ouimette Mike Officer S-Sale D Common Stock 4,755 17.55 83.5K 60,443
2023-07-17 Ouimette Mike Officer S-Sale D Common Stock 12,778 18.01 230.1K 65,198
2023-07-17 Lefebvre Eric Officer S-Sale D Common Stock 22,321 18.01 402.0K 167,215
2023-07-17 Hull Hans Officer S-Sale D Common Stock 17,937 18.01 323.0K 219,183
2023-07-17 Cummings Keith Lamont Officer S-Sale D Common Stock 19,771 18.01 356.1K 203,999
2023-07-17 Coulie Bernard Director / Officer S-Sale D Common Stock 70,150 18.01 1.26M 342,103
2023-07-14 Ouimette Mike Officer A-Award A Common Stock 27,187 0.00 77,976
2023-07-14 Lefebvre Eric Officer A-Award A Common Stock 43,750 0.00 189,536
2023-07-14 Hull Hans Officer A-Award A Common Stock 35,156 0.00 237,120
2023-07-14 Cummings Keith Lamont Officer A-Award A Common Stock 38,750 0.00 223,770
2023-07-14 Coulie Bernard Director / Officer A-Award A Common Stock 137,500 0.00 412,253
2023-06-13 Cummings Keith Lamont Officer M-Exempt A Common Stock 30,750 2.08 64.0K 185,020
2023-06-09 Cummings Keith Lamont Officer M-Exempt A Common Stock 5,800 2.08 12.1K 154,270
2023-06-07 Shah Smital Director A-Award A Stock Option (Right to Buy) 14,000 23.09 323.3K 14,000
2023-06-07 PYOTT DAVID E I Director A-Award A Stock Option (Right to Buy) 14,000 23.09 323.3K 14,000
2023-06-07 MCCOURT Thomas A Director A-Award A Stock Option (Right to Buy) 14,000 23.09 323.3K 14,000
2023-06-07 Knobil Katharine Director A-Award A Stock Option (Right to Buy) 14,000 23.09 323.3K 14,000
2023-06-07 Huh Hoyoung Director A-Award A Stock Option (Right to Buy) 14,000 23.09 323.3K 14,000
2023-06-07 Curnutte John T Director A-Award A Stock Option (Right to Buy) 14,000 23.09 323.3K 14,000
2023-06-07 Cline Darren S Director A-Award A Stock Option (Right to Buy) 14,000 23.09 323.3K 14,000
2023-06-07 CROWELL GAYLE A Director A-Award A Stock Option (Right to Buy) 14,000 23.09 323.3K 14,000
2023-06-07 Bruhn Suzanne Louise Director A-Award A Stock Option (Right to Buy) 14,000 23.09 323.3K 14,000
2023-04-03 Ouimette Mike Officer S-Sale D Common Stock 2,677 26.74 71.6K 50,989
2023-03-30 Ouimette Mike Officer S-Sale D Common Stock 4,874 26.52 129.3K 53,666
2023-03-30 Lefebvre Eric Officer S-Sale D Common Stock 11,245 26.52 298.2K 145,786
2023-03-30 Hull Hans Officer S-Sale D Common Stock 9,036 26.52 239.6K 201,964
2023-03-30 Cummings Keith Lamont Officer S-Sale D Common Stock 9,960 26.52 264.1K 148,470
2023-03-30 Coulie Bernard Director / Officer S-Sale D Common Stock 35,339 26.52 937.2K 274,753
2023-03-29 Ouimette Mike Officer A-Award A Common Stock 13,593 0.00 58,540
2023-03-29 Lefebvre Eric Officer A-Award A Common Stock 21,874 0.00 157,031
2023-03-29 Hull Hans Officer A-Award A Common Stock 17,578 0.00 211,000
2023-03-29 Cummings Keith Lamont Officer A-Award A Common Stock 19,375 0.00 158,430
2023-03-29 Coulie Bernard Director / Officer A-Award A Common Stock 68,749 0.00 310,092
2023-03-06 MCCOURT Thomas A Director A-Award A Stock Option (Right to Buy) 22,000 31.11 684.4K 22,000
2023-03-06 Cline Darren S Director A-Award A Stock Option (Right to Buy) 22,000 31.11 684.4K 22,000
2023-02-03 Coulie Bernard Director / Officer S-Sale D Common Stock 5,262 34.08 179.3K 240,112
2023-02-02 Coulie Bernard Director / Officer S-Sale D Common Stock 13,395 34.13 457.1K 241,717
2023-02-01 Coulie Bernard Director / Officer M-Exempt D Stock Option (right to buy) 15,000 6.22 93.3K 357,262
2023-01-31 Coulie Bernard Director / Officer S-Sale D Common Stock 15,000 34.92 523.8K 240,112
2023-01-30 Coulie Bernard Director / Officer S-Sale D Common Stock 3,605 34.66 124.9K 240,112
2023-01-27 Coulie Bernard Director S-Sale D Common Stock 221 36.64 8.1K 409,317
2023-01-26 Coulie Bernard Director M-Exempt D Stock Option (right to buy) 15,000 0.00 172,380
2023-01-25 Ouimette Mike Director A-Award A Stock Option (right to buy) 55,000 0.00 55,000
2023-01-25 Lefebvre Eric Director / Officer A-Award A Stock Option (right to buy) 80,000 0.00 80,000
2023-01-25 Hull Hans Director / Officer A-Award A Common Stock 54,000 0.00 192,191
2023-01-25 Cummings Keith Lamont Director / Officer A-Award A Common Stock 54,000 0.00 138,424
2023-01-25 Coulie Bernard Director S-Sale D Common Stock 13,304 32.40 431.1K 95,508
2023-01-24 Coulie Bernard Director M-Exempt D Stock Option (right to buy) 15,000 0.00 217,380
2023-01-23 Ouimette Mike Director S-Sale D Common Stock 20,000 34.19 683.9K 5,947
2023-01-23 Lefebvre Eric Director / Officer S-Sale D Common Stock 67,500 34.48 2.33M 76,926
2023-01-23 Cummings Keith Lamont Director / Officer M-Exempt D Stock Option (right to buy) 17,500 0.00 18,198
2023-01-23 Coulie Bernard Director M-Exempt D Stock Option (right to buy) 15,000 0.00 232,380
2023-01-19 Cheung Lily Director / Officer A-Award A Stock Option (Right to Buy) 123,000 0.00 123,000
2023-01-09 Coulie Bernard Director M-Exempt D Stock Option (right to buy) 5,000 0.00 247,380
2023-01-06 Coulie Bernard Director M-Exempt D Stock Option (right to buy) 15,000 0.00 252,380
2023-01-04 Coulie Bernard Director M-Exempt A Common Stock 15,000 2.08 31.2K 108,812
2023-01-03 Coulie Bernard Director M-Exempt D Stock Option (right to buy) 15,000 0.00 282,380
2022-12-22 Ouimette Mike Director S-Sale D Common Stock 2,928 19.38 56.7K 5,947
2022-12-22 Cummings Keith Lamont Director / Officer M-Exempt D Stock Option (right to buy) 4,000 0.00 146,097
2022-12-20 Ouimette Mike Director S-Sale D Common Stock 4,719 19.10 90.1K 8,875
2022-12-20 Lefebvre Eric Director / Officer S-Sale D Common Stock 10,887 19.10 208.0K 144,426
2022-12-20 Hull Hans Director / Officer S-Sale D Common Stock 8,748 19.10 167.1K 138,191
2022-12-20 Cummings Keith Lamont Director / Officer S-Sale D Common Stock 9,643 19.10 184.2K 80,424
2022-12-20 Coulie Bernard Director S-Sale D Common Stock 34,212 19.10 653.5K 93,812
2022-12-19 Ouimette Mike Director A-Award A Common Stock 13,594 0.00 13,594
2022-12-19 Lefebvre Eric Director / Officer A-Award A Common Stock 21,876 0.00 155,313
2022-12-19 Hull Hans Director / Officer A-Award A Common Stock 17,578 0.00 146,939
2022-12-19 Cummings Keith Lamont Director / Officer A-Award A Common Stock 19,375 0.00 90,067
2022-12-19 Coulie Bernard Director A-Award A Common Stock 68,751 0.00 128,024
2022-11-29 Third Rock Ventures III, L.P. Director J-Other D Common Stock 2,000,000 0.00 1,839,160
2022-10-25 Lefebvre Eric Officer S-Sale D Common Stock 5,000 25.05 125.2K 133,437
2022-09-14 Knobil Katharine Director A-Award A Stock Option (Right to Buy) 30,000 24.23 726.9K 30,000
2022-09-12 Coulie Bernard Director / Officer M-Exempt A Common Stock 12,502 2.08 26.0K 71,775
2022-07-12 Coulie Bernard Director / Officer M-Exempt A Common Stock 12,498 2.08 26.0K 71,771
2022-07-11 Lefebvre Eric Officer S-Sale D Common Stock 3,000 20.00 60.0K 138,436
2022-07-11 Coulie Bernard Director / Officer M-Exempt D Stock Option (right to buy) 15,000 2.08 31.2K 322,380
2022-06-16 Shah Smital Director A-Award A Stock Option (right to buy) 15,000 0.00 15,000
2022-06-16 PYOTT DAVID E I Director A-Award A Stock Option (right to buy) 15,000 0.00 15,000
2022-06-16 Huh Hoyoung Director A-Award A Stock Option (right to buy) 15,000 0.00 15,000
2022-06-16 Exter Neil Director A-Award A Stock Option (right to buy) 15,000 6.80 102.0K 15,000
2022-06-16 Curnutte John T Director A-Award A Stock Option (right to buy) 15,000 0.00 15,000
2022-06-16 CROWELL GAYLE A Director A-Award A Stock Option (right to buy) 15,000 6.80 102.0K 15,000
2022-06-16 Bruhn Suzanne Louise Director A-Award A Stock Option (right to buy) 15,000 6.80 102.0K 15,000
2022-01-26 Ouimette Mike Officer A-Award A Stock Option (right to buy) 87,000 11.86 1.03M 87,000
2022-01-26 Lefebvre Eric Officer A-Award A Stock Option (right to buy) 140,000 11.86 1.66M 140,000
2022-01-26 Hull Hans Officer A-Award A Stock Option (right to buy) 112,500 11.86 1.33M 112,500
2022-01-26 Cummings Keith Lamont Officer A-Award A Stock Option (right to buy) 124,000 11.86 1.47M 124,000
2022-01-26 Coulie Bernard Director / Officer A-Award A Stock Option (right to buy) 440,000 11.86 5.22M 440,000
2021-09-03 Cummings Keith Lamont Officer M-Exempt D Stock Option (right to buy) 20,000 2.08 41.6K 150,097
2021-06-29 Shah Smital Director A-Award A Stock Option (right to buy) 13,286 28.20 374.7K 13,286
2021-06-29 PYOTT DAVID E I Director A-Award A Stock Option (right to buy) 13,286 28.20 374.7K 13,286
2021-06-29 Huh Hoyoung Director A-Award A Stock Option (right to buy) 13,286 28.20 374.7K 13,286
2021-06-29 HOMCY CHARLES J Director A-Award A Stock Option (right to buy) 13,286 28.20 374.7K 13,286
2021-06-29 Exter Neil Director A-Award A Stock Option (right to buy) 13,286 28.20 374.7K 13,286
2021-06-29 Curnutte John T Director A-Award A Stock Option (right to buy) 13,286 28.20 374.7K 13,286
2021-06-29 CROWELL GAYLE A Director A-Award A Stock Option (right to buy) 13,286 28.20 374.7K 13,286
2021-06-29 Bruhn Suzanne Louise Director A-Award A Stock Option (right to buy) 13,286 28.20 374.7K 13,286
2021-06-18 Lefebvre Eric Officer S-Sale D Common Stock 8,750 28.62 250.4K 140,830
2021-06-14 Coulie Bernard Director / Officer S-Sale D Common Stock 3,757 32.98 123.9K 449,560
2021-05-26 Hull Hans Officer M-Exempt A Common Stock 4,500 2.08 9.4K 125,246
2021-05-14 Coulie Bernard Director / Officer S-Sale D Common Stock 503 29.28 14.7K 453,317
2021-04-14 Coulie Bernard Director / Officer S-Sale D Common Stock 3,500 30.33 106.2K 456,817
2021-04-13 Coulie Bernard Director / Officer M-Exempt D Stock Option (right to buy) 6,000 2.08 12.5K 337,380
2021-03-18 Lefebvre Eric Officer S-Sale D Common Stock 11,365 39.38 447.5K 150,715
2021-03-15 Coulie Bernard Director / Officer S-Sale D Common Stock 1,322 38.03 50.3K 462,495
2021-03-05 Cummings Keith Lamont Officer M-Exempt D Stock Option (right to buy) 20,000 2.08 41.6K 170,097
2021-02-16 Coulie Bernard Director / Officer S-Sale D Common Stock 2,100 32.87 69.0K 464,017
2021-01-23 Ouimette Mike Officer A-Award A Stock Option (right to buy) 15,520 26.50 411.3K 15,520
2021-01-23 Lefebvre Eric Officer A-Award A Stock Option (right to buy) 73,250 26.50 1.94M 73,250
2021-01-23 Hull Hans Officer A-Award A Stock Option (right to buy) 62,250 26.50 1.65M 62,250
2021-01-23 Howes Barbara Officer A-Award A Stock Option (right to buy) 42,500 26.50 1.13M 42,500
2021-01-23 Cummings Keith Lamont Officer A-Award A Stock Option (right to buy) 74,250 26.50 1.97M 74,250
2021-01-23 Coulie Bernard Director / Officer A-Award A Stock Option (right to buy) 250,000 26.50 6.63M 250,000
2021-01-14 Coulie Bernard Director / Officer S-Sale D Common Stock 2,870 26.20 75.2K 467,947
2021-01-12 PYOTT DAVID E I Director A-Award A Stock Option (right to buy) 26,573 27.71 736.3K 26,573
2020-12-30 Hull Hans Officer M-Exempt A Common Stock 3,500 2.08 7.3K 120,746
2020-12-21 Cummings Keith Lamont Officer M-Exempt D Stock Option (right to buy) 4,500 2.08 9.4K 190,097
2020-12-18 Lefebvre Eric Officer S-Sale D Common Stock 6,788 26.17 177.6K 167,792
2020-12-14 Coulie Bernard Director / Officer S-Sale D Common Stock 3,163 27.32 86.4K 471,154
2020-12-01 Cummings Keith Lamont Officer M-Exempt D Stock Option (right to buy) 7,143 6.22 44.4K 35,698
2020-10-09 Ouimette Mike Officer A-Award A Stock Option (right to buy) 108,240 24.32 2.63M 108,240
2020-10-01 Ouimette Mike Officer 0 0.00 0
2020-06-05 Third Rock Ventures III, L.P. 10% Owner C-Conversion A Common Stock 5,559,440 0.00 5,839,160
2020-06-05 Redmile Group, LLC 10% Owner C-Conversion A Common Stock 1,910,657 0.00 1,910,657
2020-06-05 Hull Hans Officer C-Conversion A Common Stock 5,079 0.00 117,246
2020-06-05 Huh Hoyoung Director C-Conversion A Series A Preferred Stock 1,000,000 0.00 0
2020-06-05 Howes Barbara Officer C-Conversion D Series C Preferred Stock 27,322 0.00 0
2020-06-05 Exter Neil Director C-Conversion D Series A Preferred Stock 0 0.00 0
2020-06-05 Cummings Keith Lamont Officer C-Conversion D Series C Preferred Stock 27,322 0.00 0
2020-06-05 Coulie Bernard Director / Officer C-Conversion D Series B Preferred Stock 181,594 0.00 0
2020-06-02 Third Rock Ventures III, L.P. 10% Owner I Series A Preferred Stock 2,132,867 0.00 0

Executive team

Top executives
Shares Outstanding
61.91M

Executive compensation

Executive compensation (annual)
# Year Executive Salary Bonus Stock award Option award Incentive Other Total % Stock-
based
Filing
1 2025 Bernard Coulie, M.D., Ph.D., M.B.A. President, Chief Executive Officer and Director 682.0K 1.81M 2.71M 204.6K 52.3K 5.46M 82.81%
2 2025 Éric Lefebvre, M.D. Former Chief Medical Officer 571.9K 215.6K 508.5K 762.4K 666.5K 2.72M 46.64%
3 2025 Keith Cummings, M.D., M.B.A. Chief Financial Officer 503.9K 201.6K 631.1K 946.1K 100.8K 14.0K 2.40M 65.79%
4 2025 Minnie Kuo Chief Operating Officer 470.7K 188.3K 307.5K 460.9K 103.6K 11.9K 1.54M 49.80%
5 2024 Bernard Coulie, M.D., Ph.D., M.B.A. President, Chief Executive Officer and Director 640.8K 2.23M 3.30M 384.5K 53.3K 6.61M 83.69%
6 2024 Keith Cummings, M.D., M.B.A. Chief Financial Officer 484.5K 963.6K 1.42M 213.2K 15.4K 3.10M 77.00%
7 2024 Éric Lefebvre, M.D. Chief Medical Officer 520.3K 748.2K 1.11M 228.9K 13.1K 2.62M 70.85%
8 2024 Éric Lefebvre, M.D. Former Chief Medical Officer 520.3K 748.2K 1.11M 228.9K 13.1K 2.62M 70.85%
9 2024 Hans Hull, J.D. Chief Business Officer 444.4K 549.4K 811.4K 195.5K 14.6K 2.02M 67.52%
10 2024 Mike Ouimette, J.D. Chief Legal and Compliance Officer and Secretary 442.9K 549.4K 811.4K 177.2K 13.4K 1.99M 68.24%
11 2023 Bernard Coulie, M.D., Ph.D., MBA President, Chief Executive Officer and Director 610.3K 5.07M 5.10M 335.7K 51.0K 11.17M 91.07%
12 2023 Bernard Coulie, M.D., Ph.D., M.B.A. President, Chief Executive Officer and Director 610.3K 5.07M 5.10M 335.7K 51.0K 11.17M 91.07%
13 2023 Éric Lefebvre, M.D. Chief Medical Officer 500.3K 1.98M 1.98M 220.1K 14.0K 4.69M 84.33%
14 2023 Keith Cummings, M.D., MBA Chief Financial Officer 452.8K 1.87M 1.88M 217.3K 14.0K 4.44M 84.59%
15 2023 Keith Cummings, M.D., M.B.A. Chief Financial Officer 452.8K 1.87M 1.88M 217.3K 14.0K 4.44M 84.59%
16 2023 Hans Hull, J.D. Chief Business Officer 427.3K 1.87M 1.88M 170.9K 4.3K 4.36M 86.17%
17 2023 Mike Ouimette, J.D. General Counsel and Corporate Secretary 425.9K 1.35M 1.36M 170.4K 9.8K 3.32M 81.73%
18 2023 Mike Ouimette, J.D. Chief Legal and Compliance Officer and Secretary 425.9K 1.35M 1.36M 170.4K 9.8K 3.32M 81.73%
19 2022 Bernard Coulie, M.D., Ph.D., M.B.A. President, Chief Executive Officer and Director 586.8K 6.42M 3.44M 440.0K 32.8K 10.93M 90.30%
20 2022 Bernard Coulie, M.D., Ph.D. President, Chief Executive Officer and Director 586.8K 6.42M 3.44M 440.0K 32.8K 10.93M 90.30%
21 2022 Bernard Coulie, M.D., Ph.D., MBA President, Chief Executive Officer and Director 586.8K 6.42M 3.44M 440.0K 32.8K 10.93M 90.30%
22 2022 Éric Lefebvre, M.D. Chief Medical Officer 481.1K 2.04M 1.10M 269.4K 13.0K 3.90M 80.44%
23 2022 Keith Cummings, M.D., MBA Chief Financial Officer 427.2K 1.81M 970.6K 222.1K 13.0K 3.44M 80.76%
24 2022 Keith Cummings, M.D., M.B.A. Chief Financial Officer 427.2K 1.81M 970.6K 222.1K 13.0K 3.44M 80.76%
25 2022 Hans Hull, J.D. Chief Business Officer 407.0K 1.64M 880.6K 211.6K 13.0K 3.15M 79.98%
26 2022 Mike Ouimette, J.D. General Counsel and Corporate Secretary 398.0K 1.27M 681.0K 191.0K 2.0K 2.54M 76.75%
27 2022 Mike Ouimette, J.D. Chief Legal and Compliance Officer and Secretary 398.0K 1.27M 681.0K 191.0K 2.0K 2.54M 76.75%
28 2021 Bernard Coulie, M.D., Ph.D., MBA President, Chief Executive Officer and Director 556.2K 4.30M 321.2K 42.2K 5.22M 82.39%
29 2021 Bernard Coulie, M.D., Ph.D. President, Chief Executive Officer and Director 556.2K 4.30M 321.2K 42.2K 5.22M 82.39%
30 2021 Éric Lefebvre, M.D. Chief Medical Officer 456.0K 1.26M 246.2K 11.6K 1.97M 63.84%
31 2021 Keith Cummings, M.D., MBA Chief Financial Officer 401.7K 1.28M 192.8K 11.6K 1.88M 67.82%
32 2021 Hans Hull, J.D. Chief Business Officer 385.7K 1.07M 185.2K 11.6K 1.65M 64.78%
33 2021 Barbara Howes, MBA Former Chief Human Resources Officer 254.5K 731.3K 10.1K 995.9K 73.43%
34 2021 Mike Ouimette, J.D. General Counsel and Corporate Secretary 362.7K 267.1K 174.1K 1.2K 805.0K 33.17%
35 2020 Bernard J. Coulie, M.D., Ph.D. Chief Executive Officer 499.0K 1.50M 351.0K 45.2K 2.39M 62.57%
36 2020 Bernard Coulie, M.D., Ph.D. President, Chief Executive Officer and Director 499.0K 1.50M 351.0K 45.2K 2.39M 62.57%
37 2020 Éric Lefebvre, M.D. Chief Medical Officer 425.5K 288.6K 209.2K 11.4K 874.7K 33.00%
38 2020 Hans Hull, J.D. Chief Business Officer 372.5K 279.0K 177.0K 11.4K 839.9K 33.22%
39 2019 Bernard J. Coulie, M.D., Ph.D. Chief Executive Officer 428.1K 2.0K 1.67M 219.2K 49.9K 2.37M 70.53%
40 2019 Bernard Coulie, M.D., Ph.D. President, Chief Executive Officer and Director 428.1K 2.0K 1.67M 219.2K 49.9K 2.37M 70.53%
41 2019 Hans Hull, J.D. Chief Business Officer 355.1K 75.0K 268.6K 136.4K 11.2K 846.3K 31.73%
CEO compensation breakdown

Proxy statements

Proxy statements (DEF 14A)
Filing date Form type Filing
2026-04-22 DEFA14A
2026-04-22 DEF 14A
2025-04-23 DEFA14A
2025-04-23 DEF 14A
2025-04-10 PRE 14A

Recent SEC filings

Recent SEC filings
Filing date Form type Filing
2026-05-11 8-K
2026-05-11 10-Q
2026-04-22 DEFA14A
2026-04-22 DEF 14A
2026-04-22 ARS
2026-04-17 8-K
2026-04-17 4
2026-04-17 4
2026-04-17 4
2026-04-17 4

Executive team

NameTitleCompensationGender
Bernard Coulie President, Chief Executive Officer & Director 938.9K
Keith Lamont Cummings Chief Financial Officer 820.2K
Minnie Kuo Chief Operating Officer 774.5K female
Delphine Imbert Chief Technical Officer female
Hal Chapman Scientific Founder & Member of Scientific Advisory Board male
Christopher S. Keenan Vice President of Investor Relations & Corporate Communications male
Lily Cheung Chief Human Resources Officer female
Monica Sandberg Vice President, Regulatory & Compliance
Dean Sheppard Scientific Founder & Member of Scientific Advisory Board male
Rik Derynck Scientific Founder & Member of Scientific Advisory Board
ESG Rating
B
BIOTECHNOLOGY
Rank: 418 out of 710
2026
E (Environmental)
54.6 / 56.3
Company / Sector avg.
S (Social)
60.5 / 62.4
Company / Sector avg.
G (Governance)
61.8 / 60.9
Company / Sector avg.
ESG Total
59.0 / 59.9
Company / Sector avg.
ESG Score History BIOTECHNOLOGY
Benchmark vs Sector
Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend history

Earnings history

Earnings reports

Stock splits