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ProtoKinetix, Incorporated (PKTX)

USD0.01 +0.00 (+10.67%)
US OTC Healthcare Biotechnology
Address 412 Mulberry Street 45750
Marietta, OH, US
CEO Michael Richard Guzzetta
IPO 2002-04-22
CIK 1128189 ISIN US7437221002

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Description

ProtoKinetix, Incorporated is a biotechnology firm engaged in research and development, specializing in the scientific and medical investigation of glycoproteins known as anti-freeze glycoproteins (AFGPs) and anti-aging glycoproteins (AAGPs). These AFGPs are particularly relevant for their commercial potential within the healthcare sector, with a key area of their development involving utilizing AAGPs for the treatment of dry-eye conditions. Their research efforts are bolstered by a collaborative agreement with the University of British Columbia. Originally incorporated in 1999 as RJV Network, Inc., the company adopted its current name, ProtoKinetix, Incorporated, in July 2003. Its operational headquarters are situated in Marietta, Ohio.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
USD0.01 +0.00 (+10.67%)
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Volume Profile
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Liquidity & share structure
Average Volume
33.8K
Beta
0.75
Float Shares
244.02M
Free Float %
62.3%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
+0.00% +0.00% +14.89% -34.15% -22.86% -10.00% -38.36% -79.23% -97.40% -91.52% -98.71%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
vs.
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Price Targets & DCF
Current price
0.01
Ratings Trend (MoM)
Rating 2024-11 Change
Strong Buy 0 0
Buy 0 0
Hold 0 0
Sell 0 0
Strong Sell 0 0
Quality scores
Altman Z-Score
-139.65
Distress
Piotroski F-Score
2 / 9
Weak
MOAT Score
2 / 10
No MOAT
Composite Rating
D+
Overall Score
1 / 5
Low
DCF Score
1 / 5
Low
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
1 / 5
Low
P/E Score
1 / 5
Low
P/Book Score
1 / 5
Low
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
  • EPS growth Biotechnology: +29.7%
    +16.7% Q3'25: +200.0% (vs Q3'24)
  • FCF margin FCF growth · Biotechnology: +16.2%
  • EBIT margin Biotechnology: +0.0%
  • ROIC Biotechnology: -16.1%
    -105.0% Q3'25: -135.9% (vs Q3'24)
  • Share dilution Biotechnology: -3.4%
    +7.6% Q3'25: +6.7% (vs Q3'24)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    0.00× Q3'25: 0.00× (vs Q3'24)
Valuation Multiples From To
DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (0.74) × ERP
WACC = 100% × Ke + 0% × Kd (4.1%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Current price: 0.01
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-11 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-05 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-29 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-24 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-23 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-22 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-21 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-20 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-17 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-16 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
-396.6K
OE per share TTM
0.00
Owner's Yield
-18.86%
Maintenance CapEx ratio
Maint CapEx / Avg PPE
217.0%

Ownership Overview

Ownership breakdown
At a glance
Institutional holders
1
Total invested
200.00
Insider transactions (90d)
0
Beneficial owners (>5%)
10
Beneficial owners (>5%)
# Reporting person Amount owned % of class Sole voting Shared voting Sole dispositive Shared dispositive Type Citizenship Filing date SEC filing
1 E. Smith 70.86M 22.15% 70.86M 70.86M IN States 2021-08-06
2 Grant Young 51.73M 15.20% 50.61M 1.13M 50.61M 1.13M IN Canada 2022-03-21
3 Lachlan Grant Young 32.85M 11.50% 32.85M 32.85M IN Canada 2019-02-20
4 Blake Smith 27.70M 9.20% 27.70M 27.70M IN United States 2022-03-21
5 Peter J. Richards 4.65M 6.80% 4.65M 4.65M IN Delaware 2010-02-16
6 Scott A. Fine 4.65M 6.80% 4.65M 4.65M IN Delaware 2010-02-16
7 Dr. John D. Todd 3.13M 7.01% 3.13M 3.13M 10.00 IN Canada 2007-04-04
8 Capital Management, L.L.C. 2.46M 3.60% 2.46M 2.46M OO Delaware 2010-02-16
9 Empire Capital Partners, L.P. 2.20M 3.20% 2.20M 2.20M PN Delaware 2010-02-16
10 Empire GP, L.L.C. 2.20M 3.20% 2.20M 2.20M OO Delaware 2010-02-16

Institutional Activity (13F)

Institutional ownership trend From To
13F snapshot — 2025 Q4
Investors holding
1
+0 vs prev Q
New positions
0
Closed positions
0
Increased
0
Reduced
0
Put/Call ratio
0.00
Calls held
Puts held
Top institutional holders
# Investor Shares / Δ Mkt value / Δ Own% / Δ Weight% / Δ Avg px / Perf. Hold / Status
1 WILLIAMS JONES WEALTH MANAGEMENT, LLC. 20.0K +— (+0.0%) 200.00 +— (+0.0%) 0.01% +0.000 pp 0.00% +0.000 pp USD0.10 -100.0% 27 qtrs
Ownership breakdown by holder

ETF Ownership

Top ETFs holding this stock

This company is not held by any ETF in our universe.

Insider Activity

Insider Activity — Latest Quarter
Ratio by transactions
0.00
Bearish
Buys
1
Sells
0
Shares acquired
2.00M
Shares disposed
Cash buys
1.00
Cash sales
Net activity
+2,000,000
Insider buys vs sells (history) From To
Recent insider transactions From To
Date Person Role Transaction A/D Security Shares Price Value Owned after D/I Filing
2024-09-26 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 2,000,000 0.01 20.0K 70,214,444 D
2024-06-14 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 3,100,000 0.01 31.0K 68,214,444
2024-06-13 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 3,400,000 0.01 34.0K 65,114,444
2024-03-29 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 2,500,000 0.01 25.0K 61,714,444
2024-03-20 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 666,667 0.02 10.0K 59,214,444
2023-12-26 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 7,333,334 0.02 110.0K 58,547,777
2023-10-26 Guzzetta Michael Richard Officer P-Purchase A Common Stock 20,000 0.02 330.00 736,369
2023-08-29 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 1,500,000 0.02 30.0K 51,214,443
2023-06-15 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 2,000,000 0.02 40.0K 49,714,443
2023-05-22 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 3,750,000 0.02 75.0K 47,714,443
2023-01-23 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 2,000,000 0.02 40.0K 43,964,443
2022-12-30 SMITH CLARENCE EDWARD Officer P-Purchase A Common Stock 1,850,000 0.02 37.0K 41,964,443
2022-12-21 SMITH CLARENCE EDWARD Officer P-Purchase A Common Stock 100,000 0.03 3.3K 13,572,649
2022-12-18 SMITH CLARENCE EDWARD Officer J-Other D Warrant 216,666 0.00 0
2022-12-16 SMITH CLARENCE EDWARD Officer P-Purchase A Common Stock 65,000 0.03 2.0K 13,472,649
2022-12-15 SMITH CLARENCE EDWARD Officer P-Purchase A Common Stock 78,400 0.03 2.3K 13,407,649
2022-12-14 SMITH CLARENCE EDWARD Officer P-Purchase A Common Stock 94,089 0.02 2.3K 13,329,249
2022-12-13 Young Lachlan Grant Director A-Award A Warrant 6,000,000 0.00 6,000,000
2022-12-08 SMITH CLARENCE EDWARD Officer P-Purchase A Common Stock 2,520,000 0.03 63.0K 40,114,443
2022-12-07 Young Lachlan Grant Director A-Award A Stock Option 34,280,000 0.00 34,280,000
2022-12-07 SMITH CLARENCE EDWARD Officer A-Award A Stock Option 4,750,000 0.00 4,750,000
2022-12-07 McDonough Edward P. Director J-Other D Stock Option 7,000,000 0.00 0
2022-12-07 Guzzetta Michael Richard Officer J-Other D Stock Option 4,000,000 0.00 0
2022-09-29 SMITH CLARENCE EDWARD Officer P-Purchase A Common Stock 3,333,333 0.03 100.0K 37,594,443
2022-07-11 SMITH CLARENCE EDWARD Officer P-Purchase A Common Stock 2,666,667 0.03 80.0K 34,261,110
2022-05-16 Guzzetta Michael Richard Officer P-Purchase A Common Stock 10,000 0.05 490.00 716,369
2022-03-30 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Warrant 600,000 0.05 30.0K 600,000
2022-03-18 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 1,000,000 0.05 50.0K 30,994,443
2022-03-15 Young Lachlan Grant Director A-Award A Stock Option 2,000,000 0.00 2,000,000
2022-03-15 SMITH CLARENCE EDWARD Officer J-Other D Warrant 142,857 0.00 0
2022-03-15 McDonough Edward P. Director A-Award A Stock Option 500,000 0.00 500,000
2022-03-15 Guzzetta Michael Richard Officer A-Award A Stock Option 1,500,000 0.00 1,500,000
2022-03-01 SMITH CLARENCE EDWARD Director / Officer / 10% Owner J-Other D Warrant 142,857 0.07 10.0K 0
2021-12-22 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 833,333 0.06 50.0K 29,994,443
2021-09-01 Guzzetta Michael Richard Officer P-Purchase A Common Stock 1,500 0.15 225.00 706,369
2021-08-26 Guzzetta Michael Richard Officer P-Purchase A Common Stock 1,000 0.15 150.00 704,869
2021-08-19 Guzzetta Michael Richard Officer P-Purchase A Common Stock 2,500 0.11 275.00 703,869
2021-08-04 Young Lachlan Grant 10% Owner D-Return D Stock Option 3,500,000 0.12 420.0K 0
2021-08-04 SMITH CLARENCE EDWARD Director / Officer / 10% Owner D-Return D Stock Option 5,000,000 0.26 1.30M 0
2021-08-04 McDonough Edward P. Director D-Return D Stock Option 1,000,000 0.09 90.0K 0
2021-08-04 Guzzetta Michael Richard Officer D-Return D Stock Option 3,500,000 0.12 420.0K 0
2021-04-27 Guzzetta Michael Richard Officer S-Sale D Common Stock 1,500 0.23 348.00 701,369
2021-04-26 Guzzetta Michael Richard Officer S-Sale D Common Stock 12,000 0.25 3.0K 702,869
2021-04-22 Guzzetta Michael Richard Officer S-Sale D Common Stock 11,500 0.21 2.4K 714,869
2021-04-21 Guzzetta Michael Richard Officer S-Sale D Common Stock 2,500 0.19 475.00 726,369
2021-04-13 Guzzetta Michael Richard Officer M-Exempt D Stock Option 750,000 0.07 52.5K 0
2021-01-12 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 142,857 0.07 10.0K 29,161,110
2020-11-02 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 107,143 0.07 7.5K 29,019,253
2020-08-04 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 1,000,000 0.07 65.0K 28,911,110
2020-06-12 Young Lachlan Grant 10% Owner D-Return D Stock Option 5,000,000 0.26 1.30M 0
2020-06-12 Guzzetta Michael Richard Officer A-Award A Stock Option 3,500,000 0.12 420.0K 3,500,000
2020-05-29 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 511,111 0.09 46.0K 55,411,110
2020-03-26 Young Lachlan Grant 10% Owner A-Award A Stock Option 5,000,000 0.14 700.0K 5,000,000
2020-03-26 SMITH CLARENCE EDWARD Director / Officer / 10% Owner D-Return D Stock Option 5,000,000 0.26 1.30M 0
2020-03-26 McDonough Edward P. Director A-Award A Stock Option 1,000,000 0.14 140.0K 1,000,000
2020-01-03 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 4,200 0.10 420.00 13,235,160
2019-12-31 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 45,249 0.11 5.0K 13,230,960
2019-12-30 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 21,551 0.10 2.2K 13,185,711
2019-12-19 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Warrant 216,666 0.12 26.0K 216,666
2019-11-18 Young Lachlan Grant 10% Owner A-Award A Stock Option 5,000,000 0.11 550.0K 5,000,000
2019-11-18 SMITH CLARENCE EDWARD Director / Officer / 10% Owner A-Award A Stock Option 5,000,000 0.11 550.0K 5,000,000
2019-11-18 McDonough Edward P. Director A-Award A Stock Option 1,000,000 0.11 110.0K 1,000,000
2019-11-18 Guzzetta Michael Richard Officer A-Award A Stock Option 4,000,000 0.11 440.0K 4,000,000
2019-09-24 Guzzetta Michael Richard Officer M-Exempt D Stock Option 250,000 0.07 17.5K 750,000
2019-09-20 Guzzetta Michael Richard Officer A-Award A Common Stock 1,000 0.12 115.00 75,487
2019-09-18 Guzzetta Michael Richard Officer A-Award A Common Stock 2,500 0.14 337.50 74,487
2019-07-15 Young Lachlan Grant 10% Owner A-Award A Warrant 6,000,000 0.26 1.56M 6,000,000
2019-07-15 SMITH CLARENCE EDWARD Director / Officer / 10% Owner D-Return D Stock Option 5,000,000 0.08 400.0K 0
2019-07-15 McDonough Edward P. Director D-Return D Stock Option 1,000,000 0.08 80.0K 0
2019-07-15 Guzzetta Michael Richard Officer A-Award A Stock Option 4,000,000 0.26 1.04M 4,000,000
2019-06-13 Guzzetta Michael Richard Officer P-Purchase A Common Stock 1,000 0.18 180.00 71,987
2019-06-12 Guzzetta Michael Richard Officer P-Purchase A Common Stock 1,000 0.23 230.00 70,987
2019-06-04 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 21,000 0.16 3.4K 6,467,883
2019-06-03 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 33,000 0.15 5.0K 6,446,883
2019-05-31 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 88,252 0.15 13.2K 6,413,883
2019-05-10 Guzzetta Michael Richard Officer P-Purchase A Common Stock 2,500 0.12 287.50 69,987
2019-04-29 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 41,303 0.09 3.8K 6,325,631
2019-04-25 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 34,600 0.08 2.8K 6,284,328
2019-04-23 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 60,294 0.09 5.1K 6,249,728
2019-04-22 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 12,500 0.75 9.4K 6,086,101
2019-04-15 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 38,000 0.07 2.7K 6,073,601
2019-04-11 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 9,000 0.06 576.00 6,001,601
2019-04-10 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 66,667 0.07 4.6K 5,992,601
2019-04-09 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 152,000 0.07 10.6K 5,831,692
2019-04-08 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 146,667 0.06 8.8K 5,669,692
2019-04-05 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 60,000 0.06 3.6K 5,523,025
2019-04-05 Guzzetta Michael Richard Officer P-Purchase A Common Stock 6,000 0.69 4.1K 67,487
2019-04-04 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 10,000 0.08 800.00 5,463,025
2019-04-03 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 10,000 0.08 800.00 5,453,025
2019-04-02 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 20,000 0.07 1.5K 5,443,025
2019-04-01 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 2,000,000 0.05 100.0K 61,353,833
2019-03-29 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 60,000 0.08 4.5K 5,339,725
2019-03-28 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 18,700 0.07 1.3K 5,179,725
2019-03-27 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 15,000 0.07 1.1K 5,161,025
2019-03-26 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 20,000 0.06 1.2K 5,146,025
2019-03-22 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 34,700 0.06 2.1K 5,105,725
2019-03-05 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 50,000 0.08 3.8K 5,071,025
2019-02-04 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 500,000 0.06 30.0K 59,353,833
2018-12-31 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 1,833,333 0.06 110.0K 58,853,833
2018-12-14 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 44,223 0.08 3.3K 5,021,025
2018-12-13 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 72,550 0.07 5.1K 4,976,802
2018-12-11 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 27,000 0.08 2.0K 4,976,352
2018-12-07 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 27,000 0.08 2.0K 4,903,802
2018-12-06 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 2,000 0.09 170.00 4,876,802
2018-12-04 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 13,000 0.09 1.1K 4,874,802
2018-12-03 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 5,000 0.09 425.00 4,861,802
2018-11-30 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 40,000 0.09 3.6K 4,856,802
2018-11-09 Young Lachlan Grant 10% Owner A-Award A Stock Option 5,000,000 0.09 450.0K 5,000,000
2018-11-09 SMITH CLARENCE EDWARD Director / Officer / 10% Owner A-Award A Stock Option 5,000,000 0.09 450.0K 5,000,000
2018-11-09 McDonough Edward P. Director A-Award A Stock Option 1,000,000 0.09 90.0K 1,000,000
2018-11-09 Guzzetta Michael Richard Officer A-Award A Stock Option 4,000,000 0.09 360.0K 4,000,000
2018-09-17 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 24,374 0.12 2.9K 4,746,802
2018-09-13 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 5,626 0.13 703.25 4,722,428
2018-09-12 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 50,000 0.12 6.0K 4,716,802
2018-09-11 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 50,000 0.12 6.0K 4,666,802
2018-08-02 Guzzetta Michael Richard Officer P-Purchase A Common Stock 10,000 0.07 740.00 41,500
2018-06-29 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 840,760 0.05 42.0K 57,020,500
2018-06-22 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 41,200 0.09 3.6K 4,596,802
2018-06-18 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 5,800 0.08 440.80 4,555,602
2018-06-15 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 11,900 0.10 1.2K 4,549,802
2018-06-14 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 77,000 0.10 7.7K 4,537,902
2018-06-13 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 251,000 0.10 25.1K 4,460,902
2018-06-12 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 18,600 0.09 1.6K 4,209,802
2018-06-11 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 100,000 0.09 8.5K 4,101,202
2018-06-08 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 91,000 0.08 7.3K 4,001,202
2018-06-06 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 12,700 0.09 1.1K 3,910,202
2018-06-05 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 37,300 0.09 3.2K 3,897,502
2018-06-01 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 170,000 0.08 12.8K 3,860,202
2018-05-25 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 35,000 0.06 2.1K 3,608,773
2018-05-24 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 60,000 0.06 3.3K 3,465,673
2018-05-23 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 20,000 0.05 1.1K 3,405,673
2018-05-22 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 187,000 0.05 9.0K 3,380,673
2018-05-21 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 60,000 0.05 2.9K 3,193,673
2018-05-18 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 10,000 0.04 400.00 2,956,626
2018-05-18 Guzzetta Michael Richard Officer P-Purchase A Common Stock 7,629 0.04 305.16 7,629
2018-05-17 Guzzetta Michael Richard Officer P-Purchase A Common Stock 2,500 0.04 100.00 2,500
2018-01-12 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 2,359,240 0.05 118.0K 2,359,240
2017-12-31 Young Lachlan Grant 10% Owner D Common Stock 0 0.00 6,850,000
2017-11-15 Woodward Susan Marie J-Other D Option 4,000,000 0.04 160.0K 0
2017-11-14 Guzzetta Michael Richard Officer D Stock Options 1,000,000 0.07 70.0K 0
2017-09-01 SMITH CLARENCE EDWARD Director / Officer / 10% Owner A-Award A Option 5,000,000 0.06 300.0K 5,000,000
2017-09-01 McDonough Edward P. Director A-Award A Option 1,000,000 0.06 60.0K 1,000,000
2017-06-30 McDonough Edward P. Director J-Other D Stock Option 1,000,000 0.10 100.0K 0
2017-02-06 Woodward Susan Marie Officer P-Purchase A Common Stock 250,000 0.04 10.0K 250,000
2017-02-06 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 750,000 0.04 30.0K 53,820,500
2017-01-01 Woodward Susan Marie Officer A-Award A Option 4,000,000 0.05 200.0K 4,000,000
2017-01-01 SMITH CLARENCE EDWARD Director / Officer / 10% Owner A-Award A Option 5,000,000 0.05 250.0K 5,000,000
2017-01-01 McDonough Edward P. Director A-Award A Option 1,000,000 0.05 50.0K 1,000,000
2016-12-20 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 4,000,000 0.04 160.0K 53,070,500
2016-11-30 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 3,500,000 0.04 140.0K 49,070,500
2016-11-04 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 1,250,000 0.04 50.0K 45,570,500
2016-10-14 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 50,000 0.05 2.7K 2,900,126
2016-10-12 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 55,900 0.06 3.2K 2,850,126
2016-09-29 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 500,000 0.04 20.0K 44,320,500
2016-09-23 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 22,700 0.06 1.4K 2,794,226
2016-09-22 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 20,000 0.06 1.2K 2,747,126
2016-09-21 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 25,000 0.06 1.6K 2,717,126
2016-09-20 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 5,000 0.06 300.00 2,565,226
2016-09-19 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 37,263 0.06 2.1K 2,510,226
2016-09-16 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 1,250,000 0.04 50.0K 43,820,500
2016-09-15 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 60,000 0.05 3.2K 2,472,963
2016-09-02 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 1,250,000 0.04 50.0K 42,570,500
2016-08-25 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 50,000 0.05 2.5K 2,127,410
2016-08-22 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 21,100 0.05 1.0K 2,077,410
2016-08-18 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 19,653 0.05 943.34 2,056,310
2016-07-07 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 90,000 0.06 5.4K 45,207,157
2016-07-01 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 1,850,000 0.04 74.0K 45,117,157
2016-06-30 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 50,000 0.06 3.2K 43,267,157
2016-06-24 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 40,000 0.06 2.5K 43,202,157
2016-06-23 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 4,100 0.07 278.80 43,112,157
2016-06-16 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 650,000 0.04 26.0K 42,902,157
2016-06-15 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 60,000 0.07 3.9K 42,212,157
2016-06-14 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 30,000 0.07 2.0K 42,152,157
2016-05-27 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 10,000 0.07 690.00 42,262,157
2016-05-25 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 50,000 0.06 3.2K 42,122,157
2016-05-24 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 50,000 0.06 3.2K 42,172,157
2016-05-20 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 6,000 0.06 372.00 42,122,157
2016-05-18 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 50,000 0.06 3.2K 42,022,157
2016-05-17 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 35,000 0.06 2.2K 41,972,157
2016-05-16 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 42,000 0.07 2.9K 41,919,157
2016-05-11 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 80,000 0.07 5.2K 41,877,157
2016-05-10 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 20,000 0.06 1.2K 41,797,157
2016-05-03 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 68,500 0.06 4.2K 41,653,777
2016-05-02 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 80,000 0.07 5.4K 41,498,777
2016-04-28 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 3,146 0.06 173.03 41,287,777
2016-04-27 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 100,000 0.05 5.4K 41,234,631
2016-04-26 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 36,500 0.05 1.6K 40,109,631
2016-04-25 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 78,947 0.04 3.0K 41,073,131
2016-04-22 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 105,790 0.04 4.0K 40,994,184
2016-04-21 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 173,613 0.04 6.6K 40,888,394
2016-01-01 Woodward Susan Marie Officer A-Award A Option 4,000,000 0.08 320.0K 4,000,000
2016-01-01 SMITH CLARENCE EDWARD Director / Officer / 10% Owner A-Award A Option 5,000,000 0.08 400.0K 5,000,000
2016-01-01 McDonough Edward P. Director A-Award A Option 1,000,000 0.08 80.0K 1,000,000
2015-12-30 SMITH CLARENCE EDWARD Director / Officer / 10% Owner A-Award A Common 2,000,000 0.00 40,670,500
2015-09-08 SMITH CLARENCE EDWARD Director / Officer / 10% Owner A-Award A Common Stock 625,000 0.04 25.0K 38,670,500
2015-07-01 SMITH CLARENCE EDWARD Director / Officer / 10% Owner M-Exempt D Convertible Debt 1,250,000 0.08 100.0K 0
2015-07-01 McDonough Edward P. Director D Stock Options 1,000,000 0.10 100.0K 0
2015-06-30 SMITH CLARENCE EDWARD Director / Officer / 10% Owner A-Award A Common Stock 625,000 0.08 50.0K 36,795,500
2015-03-30 Woodward Susan Marie Officer A-Award A Option 4,000,000 0.04 160.0K 800,000
2015-03-19 SMITH CLARENCE EDWARD Director / Officer / 10% Owner P-Purchase A Common Stock 1,500,000 0.05 75.0K 36,170,500

Executive team

Top executives
Shares Outstanding
391.58M

Executive compensation

Executive compensation (annual)
# Year Executive Salary Bonus Stock award Option award Incentive Other Total % Stock-
based
Filing
1 2020 Clarence E. Smith President CEO 1.92M 1.92M 100.00%
2 2020 Michael R Guzzetta Chief Financial Officer 60.0K 871.5K 931.5K 93.56%
3 2019 Clarence E. Smith President CEO 941.7K 941.7K 100.00%
4 2019 Michael R Guzzetta Chief Financial Officer 60.0K 515.1K 575.1K 89.57%
CEO compensation breakdown

Proxy statements

Proxy statements (DEF 14A)
Filing date Form type Filing
2025-09-15 DEF 14A
2025-09-05 PRE 14A
2022-02-11 DEFA14A
2022-01-14 DEFA14A
2021-12-30 DEFA14A
2021-12-30 DEF 14A
2021-12-20 PRE 14A

Recent SEC filings

Recent SEC filings
Filing date Form type Filing
2026-03-31 NT 10-K
2025-12-23 D/A
2025-11-21 8-K
2025-11-19 8-K/A
2025-11-17 8-K
2025-11-13 10-Q
2025-10-10 8-K
2025-10-02 D
2025-09-15 DEF 14A
2025-09-05 PRE 14A

Executive team

NameTitleCompensationGender
Michael Richard Guzzetta Chairman, President, CEO, CFO, Treasurer & Secretary 60.0K male
ESG Rating
B
BIOTECHNOLOGY
Rank: 112 out of 662
2021
E (Environmental)
68.6 / 56.3
Company / Sector avg.
S (Social)
64.6 / 62.4
Company / Sector avg.
G (Governance)
63.4 / 60.9
Company / Sector avg.
ESG Total
65.6 / 59.9
Company / Sector avg.
ESG Score History BIOTECHNOLOGY
Benchmark vs Sector
Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend history

Earnings history

Earnings reports

Stock splits