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PepGen Inc. (PEPG)

USD2.43 -0.02 (-0.61%)
US NASDAQ Healthcare Biotechnology
Address 321 Harrison Avenue 2118
Boston, MA, US
CEO James McArthur
Website pepgen.com
IPO 2022-05-06
CIK 1835597 ISIN US7133171055

Explore sections of this company profile

Description

PepGen Inc., a clinical-stage biotechnology company, develops oligonucleotide therapeutics for the treatment of severe neuromuscular and neurologic diseases in the United States. The company engages in the development of PGN-EDODM1, an EDO peptide-conjugated PMO, which is in Phase 2 clinical trial for the treatment of myotonic dystrophy type 1; and FREEDOM2-DM1, which is in Phase 2 for the treatment of myotonic dystrophy type 1. It is also involved in FREEDOM-OLE, an open label expansion study. The company was founded in 2018 and is based in Boston, Massachusetts.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
USD2.43 -0.02 (-0.61%)
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Volume Profile
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Liquidity & share structure
Average Volume
894.3K
Beta
1.93
Float Shares
37.03M
Free Float %
53.5%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
+0.00% -1.32% -8.54% -75.88% -76.71% -76.96% +4.17% -89.99% -88.36% -88.36% -88.36%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
vs.
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Analyst Consensus (6 ratings, all time) Buy
Price Targets & DCF
Current price
2.43
Low 4.00 +64.9%
Consensus 5.50 +126.8%
Median 5.50 +126.8%
High 7.00 +188.7%
DCF (Unlevered) 1.01 -58.2%
DCF (Levered) 1.03 -57.5%

DCF figures are point estimates: small changes in growth or discount-rate assumptions move them materially. Read them as a reference, not a precise target.

Ratings Trend (MoM) 86% Bullish
Rating 2026-05 Change
Strong Buy 0 0
Buy 6 0
Hold 0 0
Sell 0 0
Strong Sell 1 0
Price Target Summary
Period # Analysts Avg Target
Last Month 1
4.00
+64.9%
Last Quarter 1
4.00
+64.9%
Last Year 5
10.00
+312.4%
All Time 7
15.57
+542.1%
Quality scores
Altman Z-Score
-1.36
Distress
Piotroski F-Score
2 / 9
Weak
MOAT Score
3 / 10
No MOAT
Composite Rating
B-
Overall Score
2 / 5
Medium
DCF Score
4 / 5
High
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
3 / 5
Medium
P/E Score
1 / 5
Low
P/Book Score
4 / 5
High
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
  • EPS growth Biotechnology: +29.7%
    +25.6% Q1'26: +54.3% (vs Q1'25)
  • FCF margin FCF growth · Biotechnology: +16.2%
  • EBIT margin Biotechnology: +0.0%
  • ROIC Biotechnology: -16.1%
    -585.4% Q1'26: -415.4% (vs Q1'25)
  • Share dilution Biotechnology: -3.4%
    +33.7% Q1'26: +29.2% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    -0.18× Q1'26: -0.22× (vs Q1'25)
Valuation Multiples From To
DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (2.01) × ERP
WACC = 79% × Ke + 21% × Kd (4.1%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Intrinsic value (base): 1.01 Current price: 2.43
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2024
actual
Dec 2025
actual
Dec 2026
6 Rev. Ana.
5 EPS Ana.
Dec 2027
3 Rev. Ana.
6 EPS Ana.
Dec 2028
4 Rev. Ana.
4 EPS Ana.
Dec 2029
3 Rev. Ana.
2 EPS Ana.
Dec 2030
3 Rev. Ana.
2 EPS Ana.
Revenue
est: 4.00M (-100.0%)
37.46M
37.46M – 37.46M
+837.5% YoY
4.61M
4.61M – 4.61M
-87.7% YoY
31.13M
31.13M – 31.13M
+574.9% YoY
28.87M
28.87M – 28.87M
-7.3% YoY
73.04M
73.04M – 73.04M
+153.0% YoY
EBITDA
-89.09M
-92.22M
— – —
— – —
— – —
— – —
— – —
EBIT
-90.60M
-93.61M
— – —
— – —
— – —
— – —
— – —
Net Income
-89.98M
est: -96.92M (+7.2%)
-89.66M
est: -77.22M (-16.1%)
-50.28M
-61.15M – -39.40M
+34.9% YoY
-62.41M
-88.44M – -36.37M
-24.1% YoY
-55.69M
-77.69M – -33.68M
+10.8% YoY
-37.86M
-37.86M – -37.86M
+32.0% YoY
-14.07M
-14.07M – -14.07M
+62.8% YoY
SGA
21.26M
22.57M
— – —
— – —
— – —
— – —
— – —
EPS
-2.85
est: -2.73 (-4.4%)
-2.12
est: -2.27 (+6.4%)
-1.15
-1.45 – -0.93
+49.4% YoY
-1.32
-2.09 – -0.86
-15.2% YoY
-1.17
-1.84 – -0.80
+11.5% YoY
-0.90
-0.90 – -0.90
+23.4% YoY
-0.33
-0.33 – -0.33
+62.8% YoY
Recent Grade Changes (3M)
Date Firm Previous New Grade Action
2026-05-13 Wedbush Outperform Outperform Maintain
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-28 B- 2/5 4/5 1/5 1/5 3/5 1/5 4/5
2026-05-27 B- 2/5 4/5 1/5 1/5 3/5 1/5 4/5
2026-05-26 B- 2/5 4/5 1/5 1/5 3/5 1/5 4/5
2026-05-22 B- 2/5 4/5 1/5 1/5 3/5 1/5 4/5
2026-05-21 B- 2/5 4/5 1/5 1/5 3/5 1/5 4/5
2026-05-20 B- 2/5 4/5 1/5 1/5 3/5 1/5 4/5
2026-05-19 B- 2/5 4/5 1/5 1/5 3/5 1/5 4/5
2026-05-18 B- 2/5 4/5 1/5 1/5 3/5 1/5 4/5
2026-05-15 B- 2/5 4/5 1/5 1/5 3/5 1/5 4/5
2026-05-14 C+ 2/5 3/5 1/5 1/5 3/5 1/5 4/5
2026-05-13 C+ 2/5 3/5 1/5 1/5 3/5 1/5 4/5
2026-05-12 C+ 2/5 3/5 1/5 1/5 3/5 1/5 4/5
2026-05-11 C+ 2/5 3/5 1/5 1/5 3/5 1/5 3/5
2026-05-08 C+ 2/5 3/5 1/5 1/5 3/5 1/5 3/5
2026-05-07 C+ 2/5 3/5 1/5 1/5 3/5 1/5 3/5
2026-05-06 C+ 2/5 3/5 1/5 1/5 3/5 1/5 3/5
2026-05-05 C+ 2/5 3/5 1/5 1/5 3/5 1/5 3/5
2026-05-04 C+ 2/5 3/5 1/5 1/5 3/5 1/5 3/5
2026-05-01 C 2/5 3/5 1/5 1/5 2/5 1/5 3/5
2026-04-30 C 2/5 3/5 1/5 1/5 2/5 1/5 3/5
2026-04-29 C 2/5 3/5 1/5 1/5 2/5 1/5 3/5
2026-04-28 C 2/5 3/5 1/5 1/5 2/5 1/5 3/5
2026-04-27 C 2/5 3/5 1/5 1/5 2/5 1/5 3/5
2026-04-24 C 2/5 3/5 1/5 1/5 2/5 1/5 3/5
2026-04-23 C 2/5 3/5 1/5 1/5 2/5 1/5 3/5
2026-04-22 C 2/5 3/5 1/5 1/5 2/5 1/5 3/5
2026-04-21 C 2/5 3/5 1/5 1/5 2/5 1/5 3/5
2026-04-20 C 2/5 3/5 1/5 1/5 2/5 1/5 3/5
2026-04-17 C 2/5 3/5 1/5 1/5 2/5 1/5 3/5
2026-04-16 C 2/5 3/5 1/5 1/5 2/5 1/5 3/5

Owner Earnings

Owner's Earnings (history)

Owner's Earnings history not available.

Owner alignment
Owner's Earnings TTM
OE per share TTM
Owner's Yield
Maintenance CapEx ratio
Maint CapEx / Avg PPE

Ownership Overview

Ownership breakdown
At a glance
Institutional holders
102
Total invested
98.32M
Insider transactions (90d)
1
Beneficial owners (>5%)
28
Beneficial owners (>5%)
# Reporting person Amount owned % of class Sole voting Shared voting Sole dispositive Shared dispositive Type Citizenship Filing date SEC filing
1 Peter Kolchinsky 8.13M 36.30% 8.13M 10.00 HC, IN United States 2022-05-20
2 RA Capital Management, L.P. 8.13M 36.30% 8.13M 10.00 IA, PN Delaware 2022-05-20
3 Rajeev Shah 8.13M 36.30% 8.13M 10.00 HC, IN United States 2022-05-20
4 RA Capital Healthcare Fund, L.P. 6.62M 25.60% 6.62M 10.00 PN Delaware 2022-05-20
5 2 4.76M 14.70% 4.76M 4.76M CO England, United Kingdom 2024-04-09
6 EIN #00-0000000 2.34M 7.20% 2.34M 2.34M IA, HC Jersey, Channel Islands 2024-11-14
7 Abigail P. Johnson 2.19M 9.28% 2.19M IN United States of America 2023-02-09
8 FMR LLC 2.19M 9.28% 2.19M 2.19M HC Delaware 2023-02-09
9 00-0000000 2.14M 6.60% 2.14M 2.14M IV Massachusetts 2024-11-14
10 David C. Ott 1.79M 8.00% 1.79M 1.79M IN Delaware 2022-05-20
11 O. Andreas Halvorsen 1.79M 8.00% 1.79M 1.79M IN Delaware 2022-05-20
12 Rose S. Shabet 1.79M 8.00% 1.79M 1.79M IN Delaware 2022-05-20
13 Viking Global Investors LP 1.79M 8.00% 1.79M 1.79M PN Delaware 2022-05-20
14 Viking Global Opportunities GP LLC 1.79M 8.00% 1.79M 1.79M OO Delaware 2022-05-20
15 Viking Global Opportunities Illiquid Investments Sub-Master LP 1.79M 8.00% 1.79M 1.79M PN Delaware 2022-05-20
16 Viking Global Opportunities Parent GP LLC 1.79M 8.00% 1.79M 1.79M OO Delaware 2022-05-20
17 Viking Global Opportunities Portfolio GP LLC 1.79M 8.00% 1.79M 1.79M OO Delaware 2022-05-20
18 Aaron Cowen 1.66M 5.10% 1.66M 1.66M HC, IN Delaware 2024-08-12
19 Averill Master Fund, Ltd. 1.66M 5.10% 1.66M 1.66M CO Delaware 2024-08-12
20 Suvretta Capital Management, LLC 1.66M 5.10% 1.66M 1.66M IA, OO Delaware 2024-08-12
21 Qatar Investment Authority 1.25M 5.59% OO Qatar 2022-05-13
22 KAVRA 16 LLC 1.07M 4.80% 1.07M 1.07M PN Delaware 2022-05-20
23 Company, L.P. 953.6K 4.26% 953.6K PN Delaware 2022-05-10
24 James E. Flynn 953.6K 4.26% 953.6K IN Delaware 2022-05-10
25 Deerfield Mgmt V, L.P. 476.8K 2.13% 476.8K PN Delaware 2022-05-10
26 Deerfield Mgmt, L.P. 476.8K 2.13% 476.8K PN Delaware 2022-05-10
27 Deerfield Partners, L.P. 476.8K 2.13% 476.8K PN Delaware 2022-05-10
28 Deerfield Private Design Fund V, L.P. 476.8K 2.13% 476.8K PN Delaware 2022-05-10

Institutional Activity (13F)

Institutional ownership trend From To
13F snapshot — 2026 Q1
Investors holding
102
+11 vs prev Q
New positions
29
Closed positions
21
Increased
56
Reduced
26
Put/Call ratio
0.11
Calls held
1.07M
Puts held
117.3K
Top institutional holders
# Investor Shares / Δ Mkt value / Δ Own% / Δ Weight% / Δ Avg px / Perf. Hold / Status
1 RA CAPITAL MANAGEMENT, L.P. 20.06M +— (+0.0%) 130.62M +37.9M (+40.9%) 61.27% +0.000 pp 1.34% +0.196 pp USD8.03 -18.9% 15 qtrs
2 VIKING GLOBAL INVESTORS LP 3.48M +— (+0.0%) 22.67M +6.6M (+40.9%) 10.63% +0.000 pp 0.06% +0.018 pp USD6.88 -5.4% 15 qtrs
3 COMMODORE CAPITAL LP 3.40M +1.0M (+44.2%) 22.13M +11.2M (+103.2%) 10.38% +3.184 pp 1.47% +0.942 pp USD5.20 +25.2% 2 qtrs
4 VIVO CAPITAL, LLC 2.33M +— (+0.0%) 15.14M +4.4M (+40.9%) 7.10% +0.000 pp 0.98% +0.114 pp USD4.62 +40.9% 2 qtrs
5 POINT72 ASSET MANAGEMENT, L.P. 2.27M +244.4K (+12.0%) 14.81M +5.4M (+57.9%) 6.95% +0.746 pp 0.02% +0.001 pp USD1.95 +233.8% 4 qtrs
6 VANGUARD GROUP INC 2.21M +444.5K (+25.1%) 14.41M +6.2M (+76.3%) 6.76% +1.357 pp 0.00% +0.000 pp USD8.03 -18.9% 15 qtrs
7 LAURION CAPITAL MANAGEMENT LP 2.05M +160.0K (+8.5%) 13.36M +4.6M (+52.8%) 6.27% +0.489 pp 0.50% +0.347 pp USD7.24 -10.1% 15 qtrs
8 BVF INC/IL 1.92M +— (+0.0%) 12.47M +3.6M (+40.9%) 5.85% +0.000 pp 0.42% +0.061 pp USD4.62 +40.9% 2 qtrs
9 NANTAHALA CAPITAL MANAGEMENT, LLC 1.55M +1.5M (+100.0%) 10.07M +10.1M (+100.0%) 4.72% +4.725 pp 0.33% +0.333 pp USD6.51 +0.0% 1 qtrs NEW
10 JANUS HENDERSON GROUP PLC 1.50M +— (+0.0%) 9.80M +2.9M (+41.6%) 4.58% +0.000 pp 0.00% +0.001 pp USD4.62 +40.9% 2 qtrs
11 PICTET ASSET MANAGEMENT HOLDING SA 1.35M +871.1K (+181.0%) 8.80M +6.6M (+295.9%) 4.13% +2.660 pp 0.01% +0.006 pp USD5.84 +11.5% 2 qtrs
12 WOODLINE PARTNERS LP 1.31M +— (+0.0%) 8.53M +2.5M (+40.9%) 4.00% +0.000 pp 0.03% +0.005 pp USD2.93 +122.2% 4 qtrs
13 AWM INVESTMENT COMPANY, INC. 1.30M +275.0K (+26.8%) 8.46M +3.7M (+78.7%) 3.97% +0.840 pp 0.82% +0.373 pp USD5.02 +29.7% 2 qtrs
14 BLACKROCK, INC. 1.23M +784.3K (+174.2%) 8.04M +6.0M (+286.4%) 3.77% +2.395 pp 0.00% +0.000 pp USD6.97 -6.6% 6 qtrs
15 MORGAN STANLEY 1.08M +509.2K (+88.5%) 7.06M +4.4M (+165.7%) 3.31% +1.555 pp 0.00% +0.000 pp USD5.49 +18.6% 15 qtrs
16 BALYASNY ASSET MANAGEMENT L.P. 866.3K -467.3K (-35.0%) 5.64M -521.7K (-8.5%) 2.65% -1.427 pp 0.01% -0.001 pp USD4.62 +40.9% 2 qtrs
17 PERCEPTIVE ADVISORS LLC 829.9K +— (+0.0%) 5.40M +1.6M (+40.9%) 2.53% +0.000 pp 0.10% -0.014 pp USD4.62 +40.9% 2 qtrs
18 OCTAGON CAPITAL ADVISORS LP 700.0K +— (+0.0%) 4.56M +1.3M (+40.9%) 2.14% +0.000 pp 0.55% +0.063 pp USD4.62 +40.9% 2 qtrs
19 SIREN, L.L.C. 700.0K +— (+0.0%) 4.56M +1.3M (+40.9%) 2.14% +0.000 pp 0.14% +0.009 pp USD4.62 +40.9% 2 qtrs
20 GEODE CAPITAL MANAGEMENT, LLC 542.1K +341.4K (+170.1%) 3.53M +2.6M (+280.6%) 1.66% +1.042 pp 0.00% +0.000 pp USD8.83 -26.3% 15 qtrs
21 BOOTHBAY FUND MANAGEMENT, LLC 418.0K +67.6K (+19.3%) 2.72M +1.1M (+68.1%) 1.28% +0.207 pp 0.04% +0.017 pp USD4.58 +42.1% 4 qtrs
22 BOXER CAPITAL MANAGEMENT, LLC 373.9K +123.9K (+49.6%) 2.43M +1.3M (+110.7%) 1.14% +0.378 pp 0.53% +0.165 pp USD5.25 +24.0% 2 qtrs
23 BANK OF AMERICA CORP /DE/ 351.1K +348.5K (+12,977.9%) 2.29M +2.3M (+18,329.0%) 1.07% +1.064 pp 0.00% +0.000 pp USD6.55 -0.6% 15 qtrs
24 DRIEHAUS CAPITAL MANAGEMENT LLC 315.0K +— (+0.0%) 2.05M +595.4K (+40.9%) 0.96% +0.000 pp 0.01% +0.004 pp USD4.62 +40.9% 2 qtrs
25 IKARIAN CAPITAL, LLC 300.0K +300.0K (+100.0%) 1.95M +2.0M (+100.0%) 0.92% +0.916 pp 0.15% +0.153 pp USD6.51 +0.0% 1 qtrs NEW
26 MARSHALL WACE, LLP 290.6K +290.6K (+100.0%) 1.89M +1.9M (+100.0%) 0.89% +0.887 pp 0.00% +0.002 pp USD6.51 +0.0% 3 qtrs
27 CITADEL ADVISORS LLC 267.8K -29.5K (-9.9%) 1.74M +370.0K (+26.9%) 0.82% -0.090 pp 0.00% +0.000 pp USD4.62 +40.9% 5 qtrs
28 TWO SIGMA INVESTMENTS, LP 267.4K +174.9K (+189.1%) 1.74M +1.3M (+307.4%) 0.82% +0.534 pp 0.00% +0.002 pp USD5.07 +28.4% 6 qtrs
29 WALLEYE CAPITAL LLC 256.0K +256.0K (+100.0%) 1.67M +1.7M (+100.0%) 0.78% +0.782 pp 0.01% +0.005 pp USD6.51 +0.0% 1 qtrs NEW
30 GOLDMAN SACHS GROUP INC 241.6K +241.6K (+100.0%) 1.57M +1.6M (+100.0%) 0.74% +0.738 pp 0.00% +0.000 pp USD6.51 +0.0% 13 qtrs
31 STATE STREET CORP 217.5K +151.7K (+230.6%) 1.42M +1.1M (+365.8%) 0.66% +0.463 pp 0.00% +0.000 pp USD8.33 -21.8% 15 qtrs
32 ARTIA GLOBAL PARTNERS LP 205.3K +205.3K (+100.0%) 1.34M +1.3M (+100.0%) 0.63% +0.627 pp 0.21% +0.213 pp USD6.51 +0.0% 1 qtrs NEW
33 SUSQUEHANNA INTERNATIONAL GROUP, LLP 205.1K +186.9K (+1,026.9%) 1.34M +1.3M (+1,487.9%) 0.63% +0.571 pp 0.00% +0.000 pp USD6.34 +2.7% 2 qtrs
34 MILLENNIUM MANAGEMENT LLC 197.9K -302.3K (-60.4%) 1.29M -1.0M (-44.2%) 0.60% -0.923 pp 0.00% 0.000 pp USD1.61 +304.3% 6 qtrs
35 JANE STREET GROUP, LLC 192.7K +192.7K (+100.0%) 1.25M +1.3M (+100.0%) 0.59% +0.589 pp 0.00% +0.000 pp USD6.51 +0.0% 1 qtrs NEW
36 683 CAPITAL MANAGEMENT, LLC 186.9K +186.9K (+100.0%) 1.22M +1.2M (+100.0%) 0.57% +0.571 pp 0.05% +0.053 pp USD6.51 +0.0% 1 qtrs NEW
37 POLYMER CAPITAL MANAGEMENT (HK) LTD 160.0K +160.0K (+100.0%) 1.04M +1.0M (+100.0%) 0.49% +0.489 pp 0.15% +0.148 pp USD6.51 +0.0% 1 qtrs NEW
38 RENAISSANCE TECHNOLOGIES LLC 147.9K +72.2K (+95.4%) 962.8K +613.1K (+175.3%) 0.45% +0.221 pp 0.00% +0.001 pp USD4.42 +47.3% 7 qtrs
39 MONIMUS CAPITAL MANAGEMENT, LP 138.4K +33.6K (+32.1%) 901.0K +416.8K (+86.1%) 0.42% +0.103 pp 0.59% +0.296 pp USD5.08 +28.1% 2 qtrs
40 DIMENSIONAL FUND ADVISORS LP 135.2K +102.2K (+309.7%) 880.1K +727.6K (+477.1%) 0.41% +0.312 pp 0.00% +0.000 pp USD6.77 -3.8% 6 qtrs
41 SPHERA FUNDS MANAGEMENT LTD. 121.5K -50.0K (-29.2%) 790.8K -1.4K (-0.2%) 0.37% -0.153 pp 0.15% -0.014 pp USD1.42 +358.5% 3 qtrs
42 EXODUSPOINT CAPITAL MANAGEMENT, LP 120.7K -69.5K (-36.5%) 785.9K -93.0K (-10.6%) 0.37% -0.212 pp 0.01% -0.003 pp USD4.62 +40.9% 2 qtrs
43 NORTHERN TRUST CORP 118.3K +58.7K (+98.7%) 769.9K +494.8K (+179.9%) 0.36% +0.179 pp 0.00% +0.000 pp USD7.95 -18.1% 15 qtrs
44 READYSTATE ASSET MANAGEMENT LP 113.5K +113.5K (+100.0%) 738.9K +738.9K (+100.0%) 0.35% +0.347 pp 0.03% +0.030 pp USD6.51 +0.0% 1 qtrs NEW
45 ADAGE CAPITAL PARTNERS GP, L.L.C. 100.0K -1.4M (-93.1%) 651.0K -6.0M (-90.3%) 0.31% -4.122 pp 0.00% -0.010 pp USD5.90 +10.3% 15 qtrs
46 XTX TOPCO LTD 98.0K +98.0K (+100.0%) 638.2K +638.2K (+100.0%) 0.30% +0.299 pp 0.02% +0.017 pp USD6.51 +0.0% 1 qtrs NEW
47 RBF CAPITAL, LLC 95.0K -5.0K (-5.0%) 618.7K +156.7K (+33.9%) 0.29% -0.015 pp 0.03% +0.007 pp USD1.11 +486.5% 3 qtrs
48 BNP PARIBAS ARBITRAGE, SNC 89.6K +88.2K (+6,316.5%) 583.1K +576.7K (+8,940.8%) 0.27% +0.269 pp 0.00% +0.000 pp USD6.44 +1.1% 5 qtrs
49 CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD. 73.3K +35.2K (+92.5%) 477.2K +301.3K (+171.3%) 0.22% +0.108 pp 0.00% +0.001 pp USD5.53 +17.7% 2 qtrs
50 HUDSON BAY CAPITAL MANAGEMENT LP 69.4K +69.4K (+100.0%) 451.7K +451.7K (+100.0%) 0.21% +0.212 pp 0.00% +0.002 pp USD6.51 +0.0% 1 qtrs NEW
51 BRIDGEWAY CAPITAL MANAGEMENT, LLC 63.0K +— (+0.0%) 410.1K +119.1K (+40.9%) 0.19% +0.000 pp 0.01% +0.002 pp USD3.39 +92.0% 10 qtrs
52 BARCLAYS PLC 55.7K +33.7K (+153.6%) 362.7K +174.9K (+93.1%) 0.17% +0.103 pp 0.00% +0.000 pp USD5.96 +9.2% 15 qtrs
53 JUMP FINANCIAL, LLC 55.4K +55.4K (+100.0%) 360.9K +360.9K (+100.0%) 0.17% +0.169 pp 0.00% +0.004 pp USD6.51 +0.0% 1 qtrs NEW
54 RESOLUTE CAPITAL ASSET PARTNERS LLC 50.0K +50.0K (+100.0%) 325.5K +325.5K (+100.0%) 0.15% +0.153 pp 0.16% +0.157 pp USD6.51 +0.0% 1 qtrs NEW
55 GSA CAPITAL PARTNERS LLP 43.4K -2.7K (-5.9%) 283.0K +70.0K (+32.9%) 0.13% -0.008 pp 0.02% +0.007 pp USD4.62 +40.9% 2 qtrs
56 SIMPLEX TRADING, LLC 43.2K +43.2K (+100.0%) 281.2K +281.2K (+100.0%) 0.13% +0.132 pp 0.00% +0.000 pp USD6.51 +0.0% 1 qtrs NEW
57 ADAR1 CAPITAL MANAGEMENT, LLC 36.8K +— (+0.0%) 239.8K +69.6K (+40.9%) 0.11% +0.000 pp 0.02% +0.002 pp USD2.85 +128.4% 4 qtrs
58 RANGELEY CAPITAL, LLC 36.2K -7.8K (-17.7%) 235.7K +32.4K (+15.9%) 0.11% -0.024 pp 0.20% +0.020 pp USD1.93 +237.3% 4 qtrs
59 LANDSCAPE CAPITAL MANAGEMENT, L.L.C. 36.1K +36.1K (+100.0%) 235.2K +235.2K (+100.0%) 0.11% +0.110 pp 0.02% +0.016 pp USD6.51 +0.0% 1 qtrs NEW
60 RATHBONES GROUP PLC 32.0K +— (+0.0%) 208.3K +60.5K (+40.9%) 0.10% +0.000 pp 0.00% +0.000 pp USD5.08 +28.1% 10 qtrs
61 CITIGROUP INC 31.3K +29.8K (+1,997.5%) 204.0K +197.1K (+2,855.3%) 0.10% +0.091 pp 0.00% +0.000 pp USD6.66 -2.3% 15 qtrs
62 QUBE RESEARCH & TECHNOLOGIES LTD 31.2K +31.2K (+100.0%) 203.3K +203.3K (+100.0%) 0.10% +0.095 pp 0.00% +0.000 pp USD6.51 +0.0% 3 qtrs
63 SQUAREPOINT OPS LLC 31.2K +31.2K (+100.0%) 203.2K +203.2K (+100.0%) 0.10% +0.095 pp 0.00% +0.000 pp USD6.51 +0.0% 1 qtrs NEW
64 OMERS ADMINISTRATION CORP 27.6K +27.6K (+100.0%) 179.7K +179.7K (+100.0%) 0.08% +0.084 pp 0.00% +0.001 pp USD6.51 +0.0% 1 qtrs NEW
65 TREXQUANT INVESTMENT LP 24.3K +24.3K (+100.0%) 158.2K +158.2K (+100.0%) 0.07% +0.074 pp 0.00% +0.001 pp USD6.51 +0.0% 1 qtrs NEW
66 TWO SIGMA ADVISERS, LP 20.8K +20.8K (+100.0%) 135.4K +135.4K (+100.0%) 0.06% +0.064 pp 0.00% +0.000 pp USD6.51 +0.0% 1 qtrs NEW
67 ACADIAN ASSET MANAGEMENT LLC 20.8K -129.4K (-86.1%) 134.0K -559.0K (-80.7%) 0.06% -0.395 pp 0.00% -0.001 pp USD4.62 +40.9% 2 qtrs
68 AMERICAN CENTURY COMPANIES INC 15.8K +15.8K (+100.0%) 102.5K +102.5K (+100.0%) 0.05% +0.048 pp 0.00% +0.000 pp USD6.51 +0.0% 1 qtrs NEW
69 LIGHTHOUSE INVESTMENT PARTNERS, LLC 14.6K +14.6K (+100.0%) 94.9K +94.9K (+100.0%) 0.04% +0.045 pp 0.00% +0.003 pp USD6.51 +0.0% 1 qtrs NEW
70 JEFFERIES FINANCIAL GROUP INC. 13.7K +13.7K (+100.0%) 89.4K +89.4K (+100.0%) 0.04% +0.042 pp 0.00% +0.001 pp USD6.51 +0.0% 1 qtrs NEW
71 CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD. 11.2K +5.5K (+94.9%) 72.9K +46.4K (+174.6%) 0.03% +0.017 pp 0.01% +0.003 pp USD5.11 +27.4% 5 qtrs
72 BANK OF MONTREAL /CAN/ 10.0K -10.0K (-50.0%) 65.1K -27.3K (-29.5%) 0.03% -0.031 pp 0.00% +0.000 pp USD4.62 +40.9% 2 qtrs
73 TOWER RESEARCH CAPITAL LLC (TRC) 9.5K +1.7K (+21.0%) 61.8K +25.6K (+70.6%) 0.03% +0.005 pp 0.00% +0.001 pp USD7.39 -11.9% 15 qtrs
74 UBS GROUP AG 8.1K -234.4K (-96.7%) 52.5K -1.1M (-95.3%) 0.02% -0.716 pp 0.00% 0.000 pp USD4.55 +43.1% 15 qtrs
75 JPMORGAN CHASE & CO 5.2K +3.1K (+141.0%) 34.1K +24.1K (+239.5%) 0.02% +0.009 pp 0.00% +0.000 pp USD7.12 -8.6% 15 qtrs
76 MIRAE ASSET GLOBAL INVESTMENTS CO., LTD. 3.3K +2.1K (+163.5%) 21.8K +15.9K (+271.3%) 0.01% +0.006 pp 0.00% +0.000 pp USD5.28 +23.3% 5 qtrs
77 FMR LLC 1.7K -766.0 (-31.5%) 10.8K -394.0 (-3.5%) 0.01% -0.002 pp 0.00% +0.000 pp USD1.74 +274.1% 14 qtrs
78 GF FUND MANAGEMENT CO. LTD. 1.4K +671.0 (+98.8%) 8.8K +5.7K (+180.2%) 0.00% +0.002 pp 0.00% +0.000 pp USD4.96 +31.3% 5 qtrs
79 ROYAL BANK OF CANADA 383.00 -4.1K (-91.4%) 2.0K -19.0K (-90.5%) 0.00% -0.012 pp 0.00% +0.000 pp USD3.41 +90.9% 14 qtrs
80 NISA INVESTMENT ADVISORS, LLC 195.00 +— (+0.0%) 1.3K +368.0 (+40.8%) 0.00% +0.000 pp 0.00% +0.000 pp USD1.28 +408.6% 4 qtrs
81 PARALLEL ADVISORS, LLC 135.00 +135.0 (+100.0%) 879.00 +879.0 (+100.0%) 0.00% +0.000 pp 0.00% +0.000 pp USD6.50 +0.2% 1 qtrs NEW
82 121.00 +121.0 (+100.0%) 788.00 +788.0 (+100.0%) 0.00% +0.000 pp 0.00% +0.001 pp USD6.50 +0.2% 1 qtrs NEW
83 OPTIMA CAPITAL LLC 108.00 +108.0 (+100.0%) 703.00 +703.0 (+100.0%) 0.00% +0.000 pp 0.00% +0.000 pp USD6.51 +0.0% 1 qtrs NEW
84 ALLWORTH FINANCIAL LP 28.00 +28.0 (+100.0%) 183.00 +183.0 (+100.0%) 0.00% +0.000 pp 0.00% +0.000 pp USD6.50 +0.2% 1 qtrs NEW
85 LARSON FINANCIAL GROUP LLC 13.00 +13.0 (+100.0%) 85.00 +85.0 (+100.0%) 0.00% +0.000 pp 0.00% +0.000 pp USD6.46 +0.8% 1 qtrs NEW
86 ADVISOR GROUP HOLDINGS, INC. 8.00 +8.0 (+100.0%) 52.00 +52.0 (+100.0%) 0.00% +0.000 pp 0.00% +0.000 pp USD6.50 +0.2% 1 qtrs NEW
87 STEMPOINT CAPITAL LP -389.2K (-100.0%) -1.8M (-100.0%) 0.00% -1.188 pp 0.00% -0.360 pp USD 2 qtrs SOLD
88 OPALEYE MANAGEMENT INC. -75.0K (-100.0%) -346.5K (-100.0%) 0.00% -0.229 pp 0.00% -0.049 pp USD 6 qtrs SOLD
89 BURKEHILL GLOBAL MANAGEMENT, LP -10.0K (-100.0%) -46.2K (-100.0%) 0.00% -0.031 pp 0.00% -0.003 pp USD 2 qtrs SOLD
90 CWM, LLC -767.0 (-100.0%) -4.0K (-100.0%) 0.00% -0.002 pp 0.00% +0.000 pp USD 4 qtrs SOLD
91 HEIGHTS CAPITAL MANAGEMENT, INC -10.0K (-100.0%) -46.2K (-100.0%) 0.00% -0.031 pp 0.00% -0.013 pp USD 2 qtrs SOLD
92 FIFTH LANE CAPITAL, LP -70.0K (-100.0%) -323.4K (-100.0%) 0.00% -0.214 pp 0.00% -0.325 pp USD 2 qtrs SOLD
93 ECOR1 CAPITAL, LLC -800.0K (-100.0%) -3.7M (-100.0%) 0.00% -2.443 pp 0.00% -0.177 pp USD 2 qtrs SOLD
94 MONASHEE INVESTMENT MANAGEMENT LLC -300.0K (-100.0%) -1.4M (-100.0%) 0.00% -0.916 pp 0.00% -0.691 pp USD 2 qtrs SOLD
Ownership breakdown by holder

ETF Ownership

Top ETFs holding this stock Held by 19 ETFs in our universe
# ETF Weight Est. AUM exposure TER
1 iShares Micro-Cap ETF IWC 0.02% 329.4K 0.60%
2 iShares Nasdaq US Biotechnology UCITS ETF BTEC.L 0.01% 137.4K 0.35%
3 iShares Nasdaq US Biotechnology UCITS ETF BTEE.L 0.01% 9.2K 0.35%
4 iShares Biotechnology ETF IBB 0.01% 1.07M 0.44%
5 Invesco NASDAQ Biotech UCITS ETF SBIO.L 0.01% 51.6K 0.40%
6 Invesco Nasdaq Biotechnology ETF IBBQ 0.01% 8.3K 0.19%
7 ProShares Ultra Nasdaq Biotechnology BIB 0.01% 5.4K 1.19%
8 Avantis U.S. Small Cap Equity ETF AVSC 0.00% 99.7K 0.25%
9 Vanguard Extended Market ETF VXF 0.00% 705.1K 0.05%
10 Vanguard U.S. Total Market Index ETF VUN.TO 0.00% 12.3K 0.17%

Insider Activity

Insider Activity — Latest Quarter
Ratio by transactions
1.67
Bullish
Ratio by volume
3.00
Bullish
Buys
10
Sells
6
Shares acquired
1.86M
Shares disposed
9.2K
Cash buys
Cash sales
6.00
Net activity
+1,853,567
Insider buys vs sells (history) From To
Recent insider transactions From To
Date Person Role Transaction A/D Security Shares Price Value Owned after D/I Filing
2026-05-21 Kasraian Kasra Officer S-Sale D Common Stock 1,233 1.41 1.7K 50,074 D
2026-03-04 STRECK PAUL Officer S-Sale D Common Stock 1,832 6.23 11.4K 76,273 D
2026-03-04 McArthur James G Director / Officer S-Sale D Common Stock 5,144 6.23 32.0K 296,457 D
2026-03-04 Donnelly Noel Officer S-Sale D Common Stock 2,032 6.23 12.7K 111,655 D
2026-03-01 Vittiglio Joseph Officer A-Award A Common Stock 30,717 0.00 65,717 D
2026-03-01 STRECK PAUL Officer A-Award A Stock Option (Right to Buy) 196,500 6.22 1.22M 196,500 D
2026-03-01 McArthur James G Director / Officer A-Award A Common Stock 187,688 0.00 301,601 D
2026-03-01 Kasraian Kasra Officer A-Award A Common Stock 34,557 0.00 51,307 D
2026-03-01 Donnelly Noel Officer A-Award A Common Stock 76,793 0.00 113,687 D
2025-12-08 Vittiglio Joseph Officer 0 0.00 0
2025-11-04 STRECK PAUL Officer D-Return D Stock Option (Right to Buy) 40,000 9.83 393.2K 0 D
2025-11-04 McArthur James G Director / Officer D-Return D Stock Option (Right to Buy) 466,095 12.00 5.59M 0 D
2025-11-04 Donnelly Noel Officer D-Return D Stock Option (Right to Buy) 144,000 16.62 2.39M 0 D
2025-09-30 Oxford Science Enterprises plc 10% Owner P-Purchase A Common Stock 200,000 3.20 640.0K 4,955,388 D
2025-09-26 RA CAPITAL MANAGEMENT, L.P. Director / 10% Owner P-Purchase A Common Stock 9,375,000 3.20 30.00M 18,554,273 I
2025-06-04 Resnick Joshua Director A-Award A Stock Option (Right to Buy) 16,000 1.51 24.2K 16,000 D
2025-06-04 RA CAPITAL MANAGEMENT, L.P. Director / 10% Owner A-Award A Stock Option (Right to Buy) 16,000 1.51 24.2K 16,000 I
2025-06-04 Mayer Howard Director A-Award A Stock Option (Right to Buy) 16,000 1.51 24.2K 16,000 D
2025-06-04 KEATING LAURIE Director A-Award A Stock Option (Right to Buy) 16,000 1.51 24.2K 16,000 D
2025-06-04 HENSON HEIDI Director A-Award A Stock Option (Right to Buy) 16,000 1.51 24.2K 16,000 D
2025-06-04 Dable Habib J Director A-Award A Stock Option (Right to Buy) 16,000 1.51 24.2K 16,000 D
2025-05-30 STRECK PAUL Officer P-Purchase A Common Stock 8,375 1.24 10.4K 27,805 D
2025-05-20 Kasraian Kasra Officer A-Award A Stock Option (Right to Buy) 75,000 1.58 118.5K 75,000 D
2025-04-17 McArthur James G Director / Officer P-Purchase A Common Stock 10,000 1.36 13.6K 113,913 D
2025-04-08 McArthur James G Director / Officer P-Purchase A Common Stock 41,500 1.15 47.7K 103,913 D
2025-03-27 Wyman Lisa Director 0 0.00 0
2025-03-27 Finer Mitchell H. Director 0 0.00 0
2025-03-03 STRECK PAUL Officer A-Award A Stock Option (Right to Buy) 87,000 2.81 244.5K 87,000 D
2025-03-03 McArthur James G Director / Officer A-Award A Stock Option (Right to Buy) 271,875 2.81 764.0K 271,875 D
2025-03-03 Donnelly Noel Officer A-Award A Stock Option (Right to Buy) 104,250 2.81 292.9K 104,250 D
2025-03-03 DeLena Mary Beth Officer A-Award A Stock Option (Right to Buy) 60,000 2.81 168.6K 60,000 D
2025-02-26 Donnelly Noel Officer S-Sale D Common Stock 1,527 1.68 2.6K 1,673 D
2025-02-26 DeLena Mary Beth Officer S-Sale D Common Stock 1,432 1.68 2.4K 1,568 D
2025-02-24 Donnelly Noel Officer A-Award A Common Stock 3,200 0.00 3,200 D
2025-02-24 DeLena Mary Beth Officer A-Award A Common Stock 3,000 0.00 3,000 D
2024-08-19 STRECK PAUL Officer A-Award A Stock Option (Right to Buy) 40,000 9.83 393.2K 242,816
2024-07-25 Mellion Michelle L Officer M-Exempt D Stock Option (Right to Buy) 7,571 10.21 77.3K 50,000
2024-07-24 Mellion Michelle L Officer M-Exempt D Stock Option (Right to Buy) 201 10.21 2.1K 57,571
2024-07-18 Mellion Michelle L Officer M-Exempt D Stock Option (Right to Buy) 12,625 10.21 128.9K 57,772
2024-07-16 Mellion Michelle L Officer M-Exempt D Stock Option (Right to Buy) 5,901 10.21 60.2K 70,397
2024-07-12 Mellion Michelle L Officer M-Exempt D Stock Option (Right to Buy) 3,288 10.21 33.6K 76,298
2024-07-02 Mellion Michelle L Officer M-Exempt D Stock Option (Right to Buy) 37 10.21 377.77 79,586
2024-07-01 Mellion Michelle L Officer M-Exempt D Stock Option (Right to Buy) 875 10.21 8.9K 79,623
2024-06-24 Mellion Michelle L Officer M-Exempt A Common Stock 9,260 10.21 94.5K 9,260
2024-06-20 Resnick Joshua Director A-Award A Stock Option (Right to Buy) 13,000 16.80 218.4K 13,000
2024-06-20 RA CAPITAL MANAGEMENT, L.P. Director / 10% Owner A-Award A Stock Option (Right to Buy) 13,000 16.80 218.4K 13,000
2024-06-20 Mayer Howard Director A-Award A Stock Option (Right to Buy) 8,667 16.80 145.6K 8,667
2024-06-20 KEATING LAURIE Director A-Award A Stock Option (Right to Buy) 13,000 16.80 218.4K 13,000
2024-06-20 HENSON HEIDI Director A-Award A Stock Option (Right to Buy) 13,000 16.80 218.4K 13,000
2024-06-20 Dable Habib J Director A-Award A Stock Option (Right to Buy) 13,000 16.80 218.4K 13,000
2024-06-20 Ashton Christopher Director A-Award A Stock Option (Right to Buy) 13,000 16.80 218.4K 13,000
2024-06-12 Mellion Michelle L Officer M-Exempt D Stock Option (Right to Buy) 1,086 10.21 11.1K 89,758
2024-06-11 Mellion Michelle L Officer M-Exempt D Stock Option (Right to Buy) 500 10.21 5.1K 90,844
2024-06-06 Mellion Michelle L Officer S-Sale D Common Stock 1,411 18.00 25.4K 0
2024-06-05 Mellion Michelle L Officer M-Exempt D Stock Option (Right to Buy) 7,245 10.21 74.0K 92,755
2024-05-17 Svenstrup Niels Officer S-Sale D Common Stock 10,000 13.41 134.1K 0
2024-03-01 Svenstrup Niels Officer A-Award A Stock Option (Right to Buy) 83,000 16.62 1.38M 83,000
2024-03-01 Mellion Michelle L Officer A-Award A Stock Option (Right to Buy) 83,000 16.62 1.38M 83,000
2024-03-01 McArthur James G Director / Officer A-Award A Stock Option (Right to Buy) 300,000 16.62 4.99M 300,000
2024-03-01 Donnelly Noel Officer A-Award A Stock Option (Right to Buy) 144,000 16.62 2.39M 144,000
2024-02-09 RA CAPITAL MANAGEMENT, L.P. Director / 10% Owner P-Purchase A Common Stock 2,557,593 10.64 27.21M 9,179,273
2024-01-15 DeLena Mary Beth Officer A-Award A Stock Option (Right to Buy) 125,000 6.87 858.8K 125,000
2023-11-30 McArthur James G Director / Officer P-Purchase A Common Stock 1,694 4.17 7.1K 1,694
2023-11-10 Mayer Howard Director A-Award A Stock Option (Right to Buy) 22,686 3.86 87.6K 22,686
2023-06-22 Resnick Joshua Director A-Award A Stock Option (Right to Buy) 12,000 9.61 115.3K 12,000
2023-06-22 KEATING LAURIE Director A-Award A Stock Option (Right to Buy) 12,000 9.61 115.3K 12,000
2023-06-22 HENSON HEIDI Director A-Award A Stock Option (Right to Buy) 12,000 9.61 115.3K 12,000
2023-06-22 Dable Habib J Director A-Award A Stock Option (Right to Buy) 9,000 9.61 86.5K 9,000
2023-06-22 Ashton Christopher Director A-Award A Stock Option (Right to Buy) 12,000 9.61 115.3K 12,000
2023-06-08 McArthur James G Director / Officer M-Exempt A Common Stock 2,381 2.71 6.5K 2,381
2023-06-07 McArthur James G Director / Officer M-Exempt A Common Stock 8,419 2.71 22.8K 8,419
2023-06-06 McArthur James G Director / Officer S-Sale D Common Stock 18,150 16.18 293.7K 0
2023-06-05 McArthur James G Director / Officer M-Exempt D Stock Option (Right to Buy) 500 2.71 1.4K 354,004
2023-06-02 McArthur James G Director / Officer S-Sale D Common Stock 1,800 16.04 28.9K 0
2023-03-24 Goyal Jaya Officer M-Exempt D Stock Option (Right to Buy) 392 10.88 4.3K 143,804
2023-03-01 Svenstrup Niels Officer A-Award A Stock Option (Right to Buy) 75,000 15.25 1.14M 75,000
2023-03-01 Mellion Michelle L Officer A-Award A Stock Option (Right to Buy) 20,000 15.25 305.0K 95,000
2023-03-01 McArthur James G Director / Officer A-Award A Stock Option (Right to Buy) 275,000 15.25 4.19M 275,000
2023-03-01 Goyal Jaya Officer A-Award A Stock Option (Right to Buy) 75,000 15.25 1.14M 75,000
2023-03-01 Donnelly Noel Officer A-Award A Stock Option (Right to Buy) 144,000 15.25 2.20M 144,000
2023-02-08 Goyal Jaya Officer M-Exempt A Common Stock 644 10.88 7.0K 644
2023-02-07 Goyal Jaya Officer M-Exempt A Common Stock 3,679 10.88 40.0K 3,679
2023-02-06 Goyal Jaya Officer M-Exempt D Stock Option (Right to Buy) 1,677 10.88 18.2K 148,519
2022-12-19 Svenstrup Niels Officer M-Exempt A Common Stock 10,000 2.71 27.1K 10,000
2022-10-03 Dable Habib J Director A-Award A Stock Option (Right to Buy) 22,686 0.00 22,686
2022-07-01 Mellion Michelle L Officer A-Award A Stock Option (Right to Buy) 100,000 0.00 100,000
2022-05-10 Shah Rajeev M. Director C-Conversion D Series B Preferred Stock 1,508,048 0.00 0
2022-05-10 RA CAPITAL MANAGEMENT, L.P. Director / 10% Owner C-Conversion A Common Stock 207,672 0.00 207,672
2022-05-10 Oxford Science Enterprises plc Director C-Conversion D Series B Preferred stock 1,575,572 0.00 0
2022-05-10 Flynn James E 10% Owner C-Conversion D Series B Preferred Stock 273,313 0.00 0
2022-05-10 Deerfield Private Design Fund V, L.P. Director C-Conversion D Series B Preferred Stock 273,313 0.00 0
2022-05-06 Svenstrup Niels Officer A-Award A Stock Option (Right to Buy) 109,874 0.00 109,874
2022-05-06 Shah Rajeev M. Director A-Award A Stock Option (Right to Buy) 11,667 0.00 11,667
2022-05-06 Resnick Joshua Director A-Award A Stock Option (Right to Buy) 11,667 12.00 140.0K 11,667
2022-05-06 RA CAPITAL MANAGEMENT, L.P. Director / 10% Owner A-Award A Stock Option (Right to Buy) 11,667 12.00 140.0K 11,667
2022-05-06 Mellion Michelle L Officer A-Award A Stock Option (Right to Buy) 16,655 0.00 16,655
2022-05-06 McArthur James G Officer A-Award A Stock Option (Right to Buy) 466,095 0.00 466,095
2022-05-06 KEATING LAURIE Director P-Purchase A Common Stock 4,166 12.00 50.0K 4,166
2022-05-06 HENSON HEIDI Director A-Award A Stock Option (Right to Buy) 11,667 0.00 11,667
2022-05-06 Goyal Jaya Officer A-Award A Stock Option (Right to Buy) 79,920 0.00 79,920
2022-05-06 Donnelly Noel Officer A-Award A Stock Option (Right to Buy) 169,037 0.00 169,037
2022-05-06 Bracegirdle Sonia Officer A-Award A Stock Option (Right to Buy) 79,547 0.00 79,547
2022-05-06 Ashton Christopher Director A-Award A Stock Option (Right to Buy) 11,667 0.00 11,667
2022-05-05 Svenstrup Niels Officer D Stock Option (Right to Buy) 84,874 8.96 760.5K 0
2022-05-05 Resnick Joshua Director 0 0.00 0
2022-05-05 RA CAPITAL MANAGEMENT, L.P. Director / 10% Owner I Series A-2 Preferred Stock 207,672 0.00 0
2022-05-05 Oxford Science Enterprises plc 10% Owner D Series B Preferred Stock 1,547,713 0.00 0
2022-05-05 Mellion Michelle L Officer 0 0.00 0
2022-05-05 McArthur James G Director / Officer D Stock Option (Right to Buy) 356,304 2.71 965.6K 0
2022-05-05 KEATING LAURIE Director D Stock Option (Right to Buy) 98,231 10.88 1.07M 0
2022-05-05 HENSON HEIDI Director D Stock Option (Right to Buy) 55,009 8.96 492.9K 0
2022-05-05 Goyal Jaya Officer D Stock Option (Right to Buy) 150,196 10.88 1.63M 0
2022-05-05 Flynn James E 10% Owner I Series B Preferred Stock 268,480 0.00 0
2022-05-05 Donnelly Noel Officer D Stock Option (Right to Buy) 203,339 10.88 2.21M 0
2022-05-05 Bracegirdle Sonia Officer D Stock Option (Right to Buy) 19,646 11.77 231.2K 0
2022-05-05 Ashton Christopher Director D Stock Option (Right to Buy) 35,630 0.00 0

Executive team

Top executives
Shares Outstanding
69.17M

Executive compensation

Executive compensation (annual)
# Year Executive Salary Bonus Stock award Option award Incentive Other Total % Stock-
based
Filing
1 2025 James McArthur, Ph.D. President and Chief Executive Officer 619.0K 428.1K 170.6K 2.09M 10.5K 3.32M 68.11%
2 2025 Noel P. Donnelly, M.B.A. Chief Financial Officer 487.1K 245.0K 99.5K 916.8K 10.5K 1.76M 57.78%
3 2025 Joseph D. Vittiglio, J.D., Chief Business and Legal Officer 31.2K 244.0K 195.7K 732.5K 116.4K 1.32M 70.33%
4 2024 James McArthur, Ph.D. President and Chief Executive Officer 594.9K 245.4K 3.58M 10.4K 4.43M 80.78%
5 2024 Noel P. Donnelly, M.B.A. Chief Financial Officer 468.4K 155.0K 1.72M 10.4K 2.35M 73.03%
6 2024 Paul Streck, M.D., M.B.A. Executive Vice President, Head of Research & Development 194.9K 132.0K 1.74M 5.8K 2.07M 83.94%
7 2023 James McArthur, Ph.D. President and Chief Executive Officer 572.0K 228.8K 2.62M 9.9K 3.43M 76.33%
8 2023 Noel P. Donnelly, M.B.A. Chief Financial Officer 450.3K 144.0K 1.37M 9.9K 1.97M 69.38%
9 2023 Michelle Mellion, M.D. Senior Vice President, Clinical Development 388.9K 109.0K 903.4K 9.9K 1.41M 64.02%
10 2022 James McArthur, Ph.D. President and Chief Executive Officer 522.3K 302.5K 3.68M 9.2K 4.51M 81.51%
11 2022 Noel P. Donnelly, M.B.A. Chief Financial Officer 433.0K 208.0K 1.33M 9.2K 1.98M 67.23%
12 2022 Niels Svenstrup, Ph.D. Senior Vice President, Chemistry, Manufacturing and Controls 333.0K 113.0K 866.9K 9.2K 1.32M 65.57%
13 2021 James McArthur, Ph.D. President and Chief Executive Officer 407.6K 190.4K 3.49M 4.09M 85.38%
14 2021 Noel P. Donnelly, M.B.A. Chief Financial Officer 91.2K 154.8K 1.53M 1.78M 86.14%
CEO compensation breakdown

Proxy statements

Proxy statements (DEF 14A)
Filing date Form type Filing
2026-04-28 DEFA14A
2026-04-28 DEF 14A
2025-04-25 DEFA14A
2025-04-25 DEF 14A

Recent SEC filings

Recent SEC filings
Filing date Form type Filing
2026-05-26 4
2026-05-21 EFFECT
2026-05-21 8-K
2026-05-18 S-3
2026-05-15 SC 13G/A
2026-05-15 SC 13G/A
2026-05-12 8-K
2026-05-12 10-Q
2026-04-28 DEFA14A
2026-04-28 DEF 14A

Executive team

NameTitleCompensationGender
James G. McArthur President, Chief Executive Officer, Treasurer, Secretary & Director 1M
Noel Donnelly Chief Financial Officer 742.6K male
Joseph D. Vittiglio Chief Business & Legal Officer and Secretary 391.6K male
Paul D. Streck Executive Vice President and Head of Research & Development 332.7K
Melissa Michaels Executive Director & Head of Regulatory Affairs CMC female
Pallavi Lonkar Vice President & Head of Preclinical female
Kasra Kasraian Chief Technology Officer
Gregory Song Executive Director & Head of Biometrics male
Hayley Parker Senior Vice President of Global Regulatory Affairs & Quality
Emiko Bryant Senior Vice President of HR & Administration female
ESG Rating
B
BIOTECHNOLOGY
Rank: 505 out of 714
2026
E (Environmental)
55.8 / 56.3
Company / Sector avg.
S (Social)
58.4 / 62.4
Company / Sector avg.
G (Governance)
59.3 / 60.9
Company / Sector avg.
ESG Total
57.8 / 59.9
Company / Sector avg.
ESG Score History BIOTECHNOLOGY
Benchmark vs Sector
Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
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Dividend history

Earnings history

Earnings reports

Stock splits