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OPKO Health, Inc. (OPK)

USD1.22 -0.01 (-0.41%)
US NASDAQ Healthcare Biotechnology
Address 4400 Biscayne Boulevard 33137
Miami, FL, US
CEO Phillip Frost
Website opko.com
IPO 1995-11-02
CIK 944809 ISIN US68375N1037

Explore sections of this company profile

Also trades on London Stock Exchange · 0KCS.L (USD) NASDAQ Global Select · OPK (USD) Tel Aviv Stock Exchange · OPK.TA (ILA)
Description

OPKO Health, Inc. operates as a healthcare enterprise with a dual focus on diagnostics and pharmaceuticals. Its operations span the United States, Ireland, Chile, Spain, Israel, Mexico, and other international markets. The company's Diagnostics division encompasses BioReference Laboratories, which delivers a comprehensive suite of laboratory testing services. These services are crucial for disease detection, diagnosis, evaluation, monitoring, and treatment, covering areas such as esoteric testing, molecular diagnostics, anatomical pathology, genetics, women's health, and correctional healthcare. BioReference serves a diverse client base, including medical practices, clinics, hospitals, employers, and government entities. Additionally, this segment provides a cutting-edge diagnostic instrument system designed for immediate, point-of-care blood test results, alongside its specialized 4Kscore testing for prostate cancer. Within the Pharmaceutical segment, OPKO offers a range of therapeutic products and a robust development pipeline. Key offerings include Rayaldee, indicated for the management of secondary hyperparathyroidism in adults suffering from stage 3 or 4 chronic kidney disease and vitamin D insufficiency. The pipeline features OPK88004, an investigational orally administered selective androgen receptor modulator; OPK88003, a peptide administered once weekly currently in Phase IIb trials for the treatment of type 2 diabetes and obesity; and hGH-CTP, a once-weekly human growth hormone injection that has successfully completed Phase III clinical trials in collaboration with Pfizer, Inc. A core strategy for this segment involves the development and commercialization of proprietary, extended-release versions of existing therapeutic proteins. Furthermore, OPKO Health supplies specialty active pharmaceutical ingredients (APIs) and is involved in the development, manufacturing, marketing, and sale of pharmaceutical, nutraceutical, veterinary, and ophthalmic products. The company also commercializes food supplements and over-the-counter products, produces and sells items primarily within the generics market, and handles the import, marketing, distribution, and sales of pharmaceutical products across various therapeutic areas, including cardiovascular conditions, vaccines, antibiotics, gastro-intestinal ailments, and hormone-related treatments, among others. Its pharmaceutical operations are further bolstered by platforms situated in Ireland, Chile, Spain, and Mexico. Founded in 1991, OPKO Health, Inc. maintains its corporate headquarters in Miami, Florida.

Market Cap & Enterprise Value
Merger & Acquisition History
Target company Ticker Date Filing
Pain Management EXEG 2002-10-31 View
PROLOR PBTH 2013-06-27 View
Brilliant Acquisition Corporation BRLI 2015-07-02 View
Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
USD1.22 -0.01 (-0.41%)
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Volume Profile
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Liquidity & share structure
Average Volume
3M
Beta
1.49
Float Shares
332.68M
Free Float %
44.1%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
+2.10% +14.96% +29.20% +21.67% +7.35% +15.87% +5.80% +5.04% -59.56% -86.27% -67.56%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
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Annual Monthly Returns
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Daily Returns Distribution
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Analyst Consensus (13 ratings, all time) Buy
Price Targets & DCF
Current price
1.22
Low 1.60 +31.7%
Consensus 2.87 +136.2%
Median 3.00 +146.9%
High 4.00 +229.2%
DCF (Unlevered) 0.10 -91.7%

DCF figures are point estimates: small changes in growth or discount-rate assumptions move them materially. Read them as a reference, not a precise target.

Ratings Trend (MoM) 63% Bullish
Rating 2026-05 Change
Strong Buy 3 0
Buy 2 0
Hold 3 0
Sell 0 0
Strong Sell 0 0
Price Target Summary
Period # Analysts Avg Target
Last Month
Last Quarter
Last Year 1
1.60
+31.7%
All Time 4
2.90
+138.7%
Quality scores
Altman Z-Score
-0.67
Distress
Piotroski F-Score
3 / 9
Average
MOAT Score
2 / 10
No MOAT
Composite Rating
C
Overall Score
2 / 5
Medium
DCF Score
1 / 5
Low
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
2 / 5
Medium
P/E Score
1 / 5
Low
P/Book Score
4 / 5
High
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
    -14.9% Q1'26: -17.2% (vs Q1'25)
  • EPS growth Biotechnology: +29.7%
    -291.1% Q1'26: +27.7% (vs Q1'25)
  • FCF margin FCF growth · Biotechnology: +16.2%
    -45.1% Q1'26: -17.0% (vs Q1'25)
  • EBIT margin Biotechnology: +0.0%
    -36.1% Q1'26: -41.1% (vs Q1'25)
  • ROIC Biotechnology: -16.1%
    -16.4% Q1'26: -14.6% (vs Q1'25)
  • Share dilution Biotechnology: -3.4%
    +8.2% Q1'26: +13.0% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    -3.40× Q1'26: -3.44× (vs Q1'25)
Valuation Multiples From To
Price Forecast (3Y) From To
Model
Adjust
P/E
Theoretical Return — If Invested Today

* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.

DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (1.41) × ERP
WACC = 72% × Ke + 28% × Kd (25.0%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Intrinsic value (base): 0.10 Current price: 1.22
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2014
actual
Dec 2015
actual
Dec 2016
actual
Dec 2017
actual
Dec 2018
actual
Dec 2019
actual
Dec 2020
actual
Dec 2021
actual
Dec 2022
actual
Dec 2023
actual
Dec 2024
actual
Dec 2025
actual
Dec 2026
6 Rev. Ana.
4 EPS Ana.
Dec 2027
6 Rev. Ana.
4 EPS Ana.
Dec 2028
3 Rev. Ana.
3 EPS Ana.
Dec 2029
2 Rev. Ana.
1 EPS Ana.
Dec 2030
1 Rev. Ana.
1 EPS Ana.
Revenue
91.10M
est: 98.50M (-7.5%)
491.70M
est: 502.11M (-2.1%)
1.22B
est: 1.25B (-2.0%)
966.01M
est: 1.18B (-18.3%)
990.30M
est: 1.01B (-2.3%)
901.94M
est: 893.70M (+0.9%)
1.44B
est: 1.38B (+4.0%)
1.77B
est: 1.70B (+4.2%)
1.00B
est: 986.82M (+1.8%)
863.50M
est: 716.37M (+20.5%)
713.14M
est: 684.92M (+4.1%)
606.88M
est: 598.10M (+1.5%)
537.77M
530.61M – 548.03M
-10.1% YoY
567.70M
552.72M – 580.96M
+5.6% YoY
609.00M
608.95M – 609.05M
+7.3% YoY
649.70M
627.90M – 665.21M
+6.7% YoY
690.05M
666.90M – 706.53M
+6.2% YoY
EBITDA
-143.84M
est: -129.94M (-10.7%)
-87.33M
est: -10.3K (-848,268.0%)
7.18M
est: -25.6K (+28,199.8%)
-163.23M
est: -24.2K (-673,041.2%)
-68.04M
est: -48.30M (-40.8%)
-189.64M
est: -202.61M (+6.4%)
155.98M
est: 235.00M (-33.6%)
83.57M
est: 261.69M (-68.1%)
-270.81M
est: -649.77M (+58.3%)
-65.52M
est: -45.65M (-43.5%)
135.28M
est: -43.65M (+409.9%)
-127.36M
est: -38.11M (-234.1%)
-34.27M
-34.92M – -33.81M
+10.1% YoY
-36.18M
-37.02M – -35.22M
-5.6% YoY
-38.81M
-38.81M – -38.81M
-7.3% YoY
-41.40M
-42.39M – -40.01M
-6.7% YoY
-43.97M
-45.02M – -42.50M
-6.2% YoY
EBIT
-158.76M
est: -134.51M (-18.0%)
-129.58M
est: -47.37M (-173.5%)
-89.39M
est: -117.65M (+24.0%)
-265.32M
est: -111.59M (-137.8%)
-165.38M
est: -168.56M (+1.9%)
-283.45M
est: -287.42M (+1.4%)
70.62M
est: 84.59M (-16.5%)
4.86M
est: 61.53M (-92.1%)
-379.47M
est: -196.82M (-92.8%)
-170.81M
est: -126.34M (-35.2%)
37.10M
est: -120.79M (+130.7%)
-218.99M
est: -105.48M (-107.6%)
-94.84M
-96.65M – -93.58M
+10.1% YoY
-100.12M
-102.45M – -97.48M
-5.6% YoY
-107.40M
-107.41M – -107.39M
-7.3% YoY
-114.58M
-117.31M – -110.73M
-6.7% YoY
-121.69M
-124.60M – -117.61M
-6.2% YoY
Net Income
-171.67M
est: -156.98M (-9.4%)
-30.03M
est: -48.58M (+38.2%)
-48.36M
est: -52.75M (+8.3%)
-305.25M
est: -181.31M (-68.4%)
-153.04M
est: -154.57M (+1.0%)
-314.93M
est: -321.48M (+2.0%)
30.59M
est: 71.14M (-57.0%)
-30.14M
est: -97.11M (+69.0%)
-328.41M
est: -209.23M (-57.0%)
-188.86M
est: -243.10M (+22.3%)
-53.22M
est: -177.14M (+70.0%)
-225.68M
est: -279.37M (+19.2%)
-229.27M
-277.14M – -197.95M
+17.9% YoY
-195.06M
-253.28M – -136.91M
+14.9% YoY
-48.47M
-142.81M – 127.8K
+75.1% YoY
-75.11M
-77.44M – -71.84M
-55.0% YoY
-60.09M
-61.96M – -57.47M
+20.0% YoY
SGA
57.94M
est: 56.63M (+2.3%)
196.58M
est: 166.47M (+18.1%)
490.90M
est: 413.42M (+18.7%)
414.63M
est: 392.12M (+5.7%)
358.40M
est: 446.94M (-19.8%)
343.31M
est: 324.38M (+5.8%)
355.57M
est: 442.26M (-19.6%)
468.86M
est: 1.47B (-68.1%)
372.67M
est: 327.17M (+13.9%)
300.56M
est: 254.66M (+18.0%)
304.22M
est: 243.48M (+24.9%)
223.00M
est: 212.62M (+4.9%)
191.17M
188.63M – 194.82M
-10.1% YoY
201.81M
196.48M – 206.52M
+5.6% YoY
216.49M
216.47M – 216.51M
+7.3% YoY
230.96M
223.21M – 236.47M
+6.7% YoY
245.30M
237.07M – 251.16M
+6.2% YoY
EPS
-0.41
est: -0.32 (-30.2%)
-0.06
est: -0.07 (+12.1%)
-0.05
est: -0.08 (+34.2%)
-0.55
est: -0.26 (-110.5%)
-0.27
est: -0.23 (-19.1%)
-0.53
est: -0.44 (-21.8%)
0.05
est: 0.03 (+83.5%)
-0.05
est: 0.04 (-203.4%)
-0.46
est: -0.44 (-4.2%)
-0.25
est: -0.33 (+25.2%)
-0.08
est: -0.18 (+57.4%)
-0.30
est: -0.35 (+13.6%)
-0.31
-0.37 – -0.26
+11.9% YoY
-0.26
-0.34 – -0.18
+13.5% YoY
-0.09
-0.19 – 0.00
+65.9% YoY
-0.10
-0.10 – -0.10
-11.1% YoY
-0.08
-0.08 – -0.08
+20.0% YoY
Recent Grade Changes (3M)
Date Firm Previous New Grade Action
2026-04-29 Barrington Research Outperform Market Perform Downgrade
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-28 C 2/5 1/5 1/5 1/5 2/5 1/5 4/5
2026-05-27 C 2/5 1/5 1/5 1/5 2/5 1/5 4/5
2026-05-26 C 2/5 1/5 1/5 1/5 2/5 1/5 4/5
2026-05-22 C 2/5 1/5 1/5 1/5 2/5 1/5 4/5
2026-05-21 C 2/5 1/5 1/5 1/5 2/5 1/5 4/5
2026-05-20 C 2/5 1/5 1/5 1/5 2/5 1/5 4/5
2026-05-19 C 2/5 1/5 1/5 1/5 2/5 1/5 4/5
2026-05-18 C 2/5 1/5 1/5 1/5 2/5 1/5 4/5
2026-05-15 C 2/5 1/5 1/5 1/5 2/5 1/5 4/5
2026-05-14 C 2/5 1/5 1/5 1/5 2/5 1/5 4/5
2026-05-13 C 2/5 1/5 1/5 1/5 2/5 1/5 5/5
2026-05-12 C 2/5 1/5 1/5 1/5 2/5 1/5 5/5
2026-05-11 C 2/5 1/5 1/5 1/5 2/5 1/5 5/5
2026-05-08 C 2/5 1/5 1/5 1/5 2/5 1/5 5/5
2026-05-07 C 2/5 1/5 1/5 1/5 2/5 1/5 5/5
2026-05-06 C 2/5 1/5 1/5 1/5 2/5 1/5 5/5
2026-05-05 C 2/5 1/5 1/5 1/5 2/5 1/5 5/5
2026-05-04 C 2/5 1/5 1/5 1/5 2/5 1/5 5/5
2026-05-01 C 2/5 1/5 1/5 1/5 2/5 1/5 5/5
2026-04-30 C 2/5 1/5 1/5 1/5 2/5 1/5 5/5
2026-04-29 C 2/5 1/5 1/5 1/5 2/5 1/5 5/5
2026-04-28 C 2/5 1/5 1/5 1/5 2/5 1/5 5/5
2026-04-27 C- 1/5 1/5 1/5 1/5 1/5 1/5 4/5
2026-04-24 C- 1/5 1/5 1/5 1/5 1/5 1/5 4/5
2026-04-23 C- 1/5 1/5 1/5 1/5 1/5 1/5 4/5
2026-04-22 C- 1/5 1/5 1/5 1/5 1/5 1/5 4/5
2026-04-21 C- 1/5 1/5 1/5 1/5 1/5 1/5 4/5
2026-04-20 C- 1/5 1/5 1/5 1/5 1/5 1/5 4/5
2026-04-17 C- 1/5 1/5 1/5 1/5 1/5 1/5 4/5
2026-04-16 C- 1/5 1/5 1/5 1/5 1/5 1/5 4/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
-188.74M
OE per share TTM
-0.24
Owner's Yield
-17.03%
Maintenance CapEx ratio
Maint CapEx / Avg PPE
13.4%

Ownership Overview

Ownership breakdown
At a glance
Institutional holders
235
Total invested
228.97M
Insider transactions (90d)
0
Beneficial owners (>5%)
26
Beneficial owners (>5%)
# Reporting person Amount owned % of class Sole voting Shared voting Sole dispositive Shared dispositive Type Citizenship Filing date SEC filing
1 David Rosen 48.71M 6.98% 48.71M IN United States of America 2024-11-13
2 Rubric Capital Management LP 48.71M 6.98% 48.71M IA, PN United States of America 2024-11-13
3 Bruce C. Holbrook 39.78M 5.80% 226.1K 39.56M 226.1K 39.56M IN 2022-06-29
4 Coe M. Magruder 39.72M 5.80% 39.72M 39.72M IN 2022-06-29
5 (1)Names of reporting persons. BlackRock, Inc. 36.12M 5.40% 34.97M 36.12M HC Delaware 2020-02-07
6 The Vanguard Group - 23-1945930 35.73M 5.24% 337.8K 35.02M 710.4K IA Pennsylvania For 2022-02-10
7 Jane Hsiao, Ph.D. 35.01M 5.20% 35.01M 35.01M IN 2020-03-20
8 (1) BlackRock, Inc. 33.97M 4.98% 32.54M 33.97M HC Delaware 2022-03-09
9 Gary J. Nabel, M.D., Ph.D. 20.01M 2.90% 155.5K 19.86M 155.5K 19.86M IN 2022-06-29
10 Elizabeth G. Nabel, M.D. 19.97M 2.90% 113.2K 19.86M 113.2K 19.86M IN 2022-06-29
11 Elias A. Zerhouni, M.D. 19.87M 2.90% 89.6K 19.78M 89.6K 19.78M IN 2022-06-29
12 EGN 2021 Trust 19.86M 2.90% 19.86M 19.86M OO 2022-06-29
13 GJN 2021 Trust 19.86M 2.90% 19.86M 19.86M OO 2022-06-29
14 EAZ Zeraz Trust 19.78M 2.90% 19.78M 19.78M OO 2022-06-29
15 Zerhouni Irrevocable Trust 19.78M 2.90% 19.78M 19.78M OO 2022-06-29
16 Inc. Fed. Id. 75-2402409 19.44M 51.90% 19.44M 10.00 CO Delaware 2007-02-16
17 Hsu Gamma Investment, L.P. 5.13M 0.80% 5.13M 5.13M PN 2020-03-20
18 75-2402409 5.06M 9.90% 5.06M 5.06M CO Delaware 2018-02-14
19 NEW VALLEY LLC 2.26M 6.20% CO : 2007-02-13
20 OPKO Health, Inc. 2.17M 8.06% CO 2024-09-18
21 4.99% (2) 488.1K 4.99% 488.1K 488.1K CO Delaware 2019-05-09
22 4.99% (1) 487.9K 4.99% 487.9K 487.9K IN Delaware 2019-05-09
23 (2) 446.4K 5.11% 446.4K 446.4K CO Delaware 2017-01-12
24 Nabel Family Investments LLC 80.0K 0.01% 80.0K 80.0K OO 2022-06-29
25 Marsh & McLennan Companies, Inc. 0.00% 2.26M 2.26M HC Delaware 2016-08-22
26 VECTOR GROUP LTD. 0.00% HC, CO : 2007-02-13

Institutional Activity (13F)

Institutional ownership trend From To
13F snapshot — 2026 Q1
Investors holding
235
+10 vs prev Q
New positions
45
Closed positions
32
Increased
104
Reduced
59
Put/Call ratio
0.40
Calls held
151.0K
Puts held
60.4K
Top institutional holders
# Investor Shares / Δ Mkt value / Δ Own% / Δ Weight% / Δ Avg px / Perf. Hold / Status
1 RUBRIC CAPITAL MANAGEMENT LP 47.79M +— (+0.0%) 60.22M -13.9M (-18.7%) 6.15% -0.967 pp 0.72% -0.116 pp USD1.26 +0.0% 8 qtrs
2 BLACKROCK, INC. 34.85M +1.7M (+5.1%) 43.91M -7.5M (-14.6%) 4.48% -0.455 pp 0.00% 0.000 pp USD1.46 -13.7% 6 qtrs
3 VANGUARD GROUP INC 32.46M -5.1M (-13.5%) 40.90M -17.3M (-29.7%) 4.18% -1.413 pp 0.00% 0.000 pp USD4.21 -70.1% 74 qtrs
4 GEODE CAPITAL MANAGEMENT, LLC 11.06M +68.0K (+0.6%) 13.94M -3.1M (-18.2%) 1.42% -0.214 pp 0.00% 0.000 pp USD3.56 -64.6% 66 qtrs
5 STATE STREET CORP 8.95M -46.2K (-0.5%) 11.28M -2.7M (-19.1%) 1.15% -0.188 pp 0.00% 0.000 pp USD3.10 -59.4% 51 qtrs
6 GOLDMAN SACHS GROUP INC 5.99M +3.6M (+150.9%) 7.54M +3.8M (+103.9%) 0.77% +0.415 pp 0.00% +0.001 pp USD1.70 -25.9% 61 qtrs
7 UBS GROUP AG 5.35M +577.2K (+12.1%) 6.74M -657.6K (-8.9%) 0.69% -0.022 pp 0.00% 0.000 pp USD1.39 -9.4% 45 qtrs
8 WHITEFORT CAPITAL MANAGEMENT, LP 4.25M -646.7K (-13.2%) 5.36M -2.2M (-29.4%) 0.55% -0.182 pp 1.37% -0.875 pp USD1.47 -14.3% 7 qtrs
9 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 3.69M -76.3K (-2.0%) 4.65M -1.2M (-20.4%) 0.48% -0.086 pp 0.00% 0.000 pp USD3.07 -59.0% 64 qtrs
10 NORTHERN TRUST CORP 3.44M -219.5K (-6.0%) 4.33M -1.3M (-23.6%) 0.44% -0.102 pp 0.00% 0.000 pp USD3.66 -65.6% 51 qtrs
11 CITADEL ADVISORS LLC 2.86M +2.6M (+921.0%) 3.60M +3.2M (+729.9%) 0.37% +0.326 pp 0.00% +0.001 pp USD1.29 -2.3% 52 qtrs
12 AWM INVESTMENT COMPANY, INC. 2.10M -100.0K (-4.5%) 2.65M -764.0K (-22.4%) 0.27% -0.057 pp 0.26% -0.064 pp USD2.19 -42.5% 45 qtrs
13 AQR CAPITAL MANAGEMENT LLC 2.03M -846.5K (-29.5%) 2.55M -1.9M (-42.7%) 0.26% -0.167 pp 0.00% -0.002 pp USD1.58 -20.3% 22 qtrs
14 JANE STREET GROUP, LLC 1.78M +1.5M (+575.4%) 2.24M +1.8M (+449.1%) 0.23% +0.189 pp 0.00% +0.000 pp USD1.28 -1.6% 48 qtrs
15 DIMENSIONAL FUND ADVISORS LP 1.61M -56.1K (-3.4%) 2.03M -550.8K (-21.3%) 0.21% -0.041 pp 0.00% 0.000 pp USD3.50 -64.0% 51 qtrs
16 WASHINGTON GROWTH STRATEGIES LLC 1.36M +— (+0.0%) 1.71M -393.3K (-18.7%) 0.17% -0.027 pp 1.10% -0.394 pp USD1.32 -4.5% 4 qtrs
17 Y.D. MORE INVESTMENTS LTD 1.31M -192.7K (-12.9%) 1.67M -564.6K (-25.3%) 0.17% -0.055 pp 0.08% -0.046 pp USD1.35 -6.7% 7 qtrs
18 PFG INVESTMENTS, LLC 1.32M -17.0K (-1.3%) 1.66M -409.2K (-19.7%) 0.17% -0.029 pp 0.08% -0.029 pp USD1.36 -7.4% 8 qtrs
19 BANK OF NEW YORK MELLON CORP 1.31M +33.2K (+2.6%) 1.65M -328.4K (-16.6%) 0.17% -0.022 pp 0.00% 0.000 pp USD4.43 -71.6% 66 qtrs
20 VOYA INVESTMENT MANAGEMENT LLC 1.10M -115.8K (-9.5%) 1.39M -499.2K (-26.4%) 0.14% -0.040 pp 0.00% -0.001 pp USD1.61 -21.7% 51 qtrs
21 MORGAN STANLEY 917.4K +79.8K (+9.5%) 1.16M -142.4K (-11.0%) 0.12% -0.007 pp 0.00% +0.000 pp USD1.70 -25.9% 51 qtrs
22 CLEARSTEAD ADVISORS, LLC 882.4K +882.4K (+100.0%) 1.11M +1.1M (+100.0%) 0.11% +0.114 pp 0.01% +0.014 pp USD1.26 +0.0% 7 qtrs
23 TEJARA CAPITAL LTD 877.9K +— (+0.0%) 1.11M -254.6K (-18.7%) 0.11% -0.018 pp 0.26% -0.450 pp USD1.30 -3.1% 7 qtrs
24 SWISS NATIONAL BANK 845.8K +— (+0.0%) 1.07M -245.3K (-18.7%) 0.11% -0.017 pp 0.00% 0.000 pp USD4.19 -69.9% 51 qtrs
25 NUVEEN, LLC 841.8K +— (+0.0%) 1.06M -244.1K (-18.7%) 0.11% -0.017 pp 0.00% 0.000 pp USD1.66 -24.1% 4 qtrs
26 INVESCO LTD. 781.7K -235.9K (-23.2%) 984.9K -592.3K (-37.6%) 0.10% -0.051 pp 0.00% 0.000 pp USD1.37 -8.0% 56 qtrs
27 TWO SIGMA INVESTMENTS, LP 734.7K -520.9K (-41.5%) 925.8K -1.0M (-52.4%) 0.09% -0.092 pp 0.00% -0.002 pp USD1.59 -20.8% 15 qtrs
28 HRT FINANCIAL LP 675.5K +675.5K (+100.0%) 851.0K +851.0K (+100.0%) 0.09% +0.087 pp 0.00% +0.003 pp USD1.26 +0.0% 1 qtrs NEW
29 UBS ASSET MANAGEMENT AMERICAS INC 673.6K +— (+0.0%) 848.7K -195.3K (-18.7%) 0.09% -0.014 pp 0.00% +0.000 pp USD2.14 -41.1% 52 qtrs
30 BARCLAYS PLC 663.2K +119.9K (+22.1%) 835.7K +26.1K (+3.2%) 0.09% +0.004 pp 0.00% +0.000 pp USD1.39 -9.4% 51 qtrs
31 ASSENAGON ASSET MANAGEMENT S.A. 652.1K -38.1K (-5.5%) 834.7K -195.3K (-19.0%) 0.08% -0.019 pp 0.00% 0.000 pp USD1.46 -13.7% 12 qtrs
32 COMMONWEALTH EQUITY SERVICES, LLC 641.5K +49.1K (+8.3%) 808.2K -109.8K (-12.0%) 0.08% -0.006 pp 0.00% 0.000 pp USD1.35 -6.7% 8 qtrs
33 GSA CAPITAL PARTNERS LLP 621.3K +621.3K (+100.0%) 783.0K +783.0K (+100.0%) 0.08% +0.080 pp 0.07% +0.068 pp USD1.26 +0.0% 1 qtrs NEW
34 BANK OF AMERICA CORP /DE/ 618.3K -695.6K (-52.9%) 779.0K -1.3M (-61.7%) 0.08% -0.116 pp 0.00% 0.000 pp USD1.64 -23.2% 52 qtrs
35 JPMORGAN CHASE & CO 579.8K +52.4K (+9.9%) 730.5K -87.0K (-10.6%) 0.07% -0.004 pp 0.00% +0.000 pp USD2.13 -40.8% 42 qtrs
36 RHUMBLINE ADVISERS 511.5K -43.9K (-7.9%) 644.5K -216.4K (-25.1%) 0.07% -0.017 pp 0.00% 0.000 pp USD4.18 -69.9% 51 qtrs
37 WELLS FARGO & COMPANY/MN 468.5K +126.0K (+36.8%) 590.3K +59.5K (+11.2%) 0.06% +0.009 pp 0.00% +0.000 pp USD1.71 -26.3% 57 qtrs
38 LEGAL & GENERAL GROUP PLC 453.3K +66.4K (+17.2%) 571.1K -27.1K (-4.5%) 0.06% +0.001 pp 0.00% +0.000 pp USD3.05 -58.7% 46 qtrs
39 ALLIANCEBERNSTEIN L.P. 448.2K -27.0K (-5.7%) 564.7K -171.8K (-23.3%) 0.06% -0.013 pp 0.00% 0.000 pp USD3.13 -59.7% 61 qtrs
40 SUSQUEHANNA INTERNATIONAL GROUP, LLP 437.3K +139.5K (+46.8%) 551.0K +89.3K (+19.4%) 0.06% +0.012 pp 0.00% +0.000 pp USD1.54 -18.2% 51 qtrs
41 CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD. 430.6K +37.9K (+9.6%) 542.6K -66.2K (-10.9%) 0.06% -0.003 pp 0.00% -0.001 pp USD1.46 -13.7% 5 qtrs
42 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 417.1K +1.7K (+0.4%) 525.5K -118.3K (-18.4%) 0.05% -0.008 pp 0.00% 0.000 pp USD5.70 -77.9% 52 qtrs
43 TWO SIGMA SECURITIES, LLC 374.5K +253.4K (+209.2%) 471.8K +284.1K (+151.4%) 0.05% +0.030 pp 0.06% +0.037 pp USD1.35 -6.7% 13 qtrs
44 PRICE T ROWE ASSOCIATES INC /MD/ 367.2K +23.9K (+7.0%) 463.0K -70.0K (-13.1%) 0.05% -0.004 pp 0.00% +0.000 pp USD2.49 -49.4% 69 qtrs
45 XTX TOPCO LTD 342.8K +342.8K (+100.0%) 431.9K +431.9K (+100.0%) 0.04% +0.044 pp 0.01% +0.011 pp USD1.26 +0.0% 11 qtrs
46 DEUTSCHE BANK AG\ 325.9K +50.7K (+18.4%) 410.6K -15.9K (-3.7%) 0.04% +0.001 pp 0.00% +0.000 pp USD1.54 -18.2% 50 qtrs
47 ENTRYPOINT CAPITAL, LLC 309.0K +270.2K (+695.9%) 389.4K +329.2K (+547.0%) 0.04% +0.034 pp 0.15% +0.129 pp USD1.30 -3.1% 2 qtrs
48 CAPTION MANAGEMENT, LLC 306.8K +— (+0.0%) 386.6K -89.0K (-18.7%) 0.04% -0.006 pp 0.00% -0.001 pp USD1.47 -14.3% 6 qtrs
49 MILLENNIUM MANAGEMENT LLC 265.3K +265.3K (+100.0%) 334.2K +334.2K (+100.0%) 0.03% +0.034 pp 0.00% +0.000 pp USD1.26 +0.0% 29 qtrs
50 ROYAL BANK OF CANADA 261.0K -11.8K (-4.3%) 329.0K -94.0K (-22.2%) 0.03% -0.007 pp 0.00% +0.000 pp USD2.43 -48.1% 51 qtrs
51 TUDOR INVESTMENT CORP ET AL 244.8K +— (+0.0%) 308.5K -71.0K (-18.7%) 0.03% -0.005 pp 0.00% 0.000 pp USD2.00 -37.0% 16 qtrs
52 MANUFACTURERS LIFE INSURANCE COMPANY, THE 229.6K -7.1K (-3.0%) 289.3K -77.6K (-21.2%) 0.03% -0.006 pp 0.00% 0.000 pp USD2.51 -49.8% 51 qtrs
53 JANUS HENDERSON GROUP PLC 206.3K +— (+0.0%) 258.9K -59.8K (-18.8%) 0.03% -0.004 pp 0.00% +0.000 pp USD2.61 -51.7% 18 qtrs
54 BALYASNY ASSET MANAGEMENT L.P. 198.8K +198.8K (+100.0%) 250.5K +250.5K (+100.0%) 0.03% +0.026 pp 0.00% +0.000 pp USD1.26 +0.0% 1 qtrs NEW
55 MIRABELLA FINANCIAL SERVICES LLP 193.7K +193.7K (+100.0%) 244.1K +244.1K (+100.0%) 0.02% +0.025 pp 0.02% +0.023 pp USD1.26 +0.0% 1 qtrs NEW
56 TWO SIGMA ADVISERS, LP 191.2K -152.9K (-44.4%) 240.9K -292.4K (-54.8%) 0.02% -0.027 pp 0.00% -0.001 pp USD2.00 -37.0% 20 qtrs
57 MIRAE ASSET GLOBAL ETFS HOLDINGS LTD. 191.1K -82.0 (0.0%) 240.8K -55.5K (-18.7%) 0.02% -0.004 pp 0.00% 0.000 pp USD1.25 +0.8% 7 qtrs
58 STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 176.3K +— (+0.0%) 222.1K -51.1K (-18.7%) 0.02% -0.004 pp 0.00% 0.000 pp USD4.78 -73.6% 51 qtrs
59 METLIFE INVESTMENT MANAGEMENT, LLC 175.7K -31.5K (-15.2%) 221.4K -99.8K (-31.1%) 0.02% -0.008 pp 0.00% -0.001 pp USD2.22 -43.2% 31 qtrs
60 GAMCO INVESTORS, INC. ET AL 175.0K +— (+0.0%) 220.5K -50.8K (-18.7%) 0.02% -0.004 pp 0.00% -0.001 pp USD3.07 -59.0% 64 qtrs
61 GABELLI FUNDS LLC 170.0K +— (+0.0%) 214.2K -49.3K (-18.7%) 0.02% -0.003 pp 0.00% 0.000 pp USD4.98 -74.7% 64 qtrs
62 INTECH INVESTMENT MANAGEMENT LLC 159.7K +16.3K (+11.4%) 201.2K -21.0K (-9.4%) 0.02% -0.001 pp 0.00% 0.000 pp USD1.46 -13.7% 6 qtrs
63 IEQ CAPITAL, LLC 157.8K -119.8K (-43.2%) 198.8K -231.5K (-53.8%) 0.02% -0.021 pp 0.00% -0.001 pp USD1.58 -20.3% 5 qtrs
64 PROSHARE ADVISORS LLC 156.4K +86.0K (+122.2%) 197.0K +87.9K (+80.6%) 0.02% +0.010 pp 0.00% +0.000 pp USD1.92 -34.4% 63 qtrs
65 ZAZOVE ASSOCIATES LLC 150.0K -57.6K (-27.7%) 189.0K -132.8K (-41.3%) 0.02% -0.012 pp 0.02% -0.013 pp USD1.66 -24.1% 5 qtrs
66 140.0K -2.0K (-1.4%) 176.4K -43.7K (-19.9%) 0.02% -0.003 pp 0.12% -0.013 pp USD1.55 -18.7% 2 qtrs
67 VAN ECK ASSOCIATES CORP 137.0K +25.2K (+22.5%) 173.0K +— (+0.0%) 0.02% +0.001 pp 0.00% +0.000 pp USD2.11 -40.3% 15 qtrs
68 QUANTBOT TECHNOLOGIES LP 122.7K +122.7K (+100.0%) 154.7K +154.7K (+100.0%) 0.02% +0.016 pp 0.01% +0.005 pp USD1.26 +0.0% 1 qtrs NEW
69 COMERICA BANK 120.0K +8.0K (+7.1%) 151.2K -22.4K (-12.9%) 0.02% -0.001 pp 0.00% +0.000 pp USD1.44 -12.5% 10 qtrs
70 GRAHAM CAPITAL MANAGEMENT, L.P. 119.7K +21.3K (+21.6%) 150.8K -1.7K (-1.1%) 0.02% +0.001 pp 0.00% +0.001 pp USD1.57 -19.7% 4 qtrs
71 HIGHLINE WEALTH PARTNERS LLC 116.7K +— (+0.0%) 147.0K -33.8K (-18.7%) 0.02% -0.002 pp 0.04% -0.007 pp USD1.91 -34.0% 14 qtrs
72 VIRTU FINANCIAL LLC 115.3K +115.3K (+100.0%) 145.0K +145.0K (+100.0%) 0.01% +0.015 pp 0.01% +0.006 pp USD1.26 +0.0% 1 qtrs NEW
73 NEW YORK STATE COMMON RETIREMENT FUND 114.3K -16.6K (-12.7%) 144.0K -58.9K (-29.0%) 0.01% -0.005 pp 0.00% 0.000 pp USD4.43 -71.6% 47 qtrs
74 ARIZONA STATE RETIREMENT SYSTEM 113.8K -14.8K (-11.5%) 143.4K -55.9K (-28.0%) 0.01% -0.005 pp 0.00% 0.000 pp USD1.85 -31.9% 24 qtrs
75 GLENMEDE TRUST CO NA 113.5K +113.5K (+100.0%) 143.0K +143.0K (+100.0%) 0.01% +0.015 pp 0.00% +0.001 pp USD1.26 +0.0% 1 qtrs NEW
76 Y-INTERCEPT (HONG KONG) LTD 112.9K +112.9K (+100.0%) 142.3K +142.3K (+100.0%) 0.01% +0.015 pp 0.00% +0.003 pp USD1.26 +0.0% 1 qtrs NEW
77 SIH PARTNERS, LLLP 104.3K -45.8K (-30.5%) 131.5K -101.2K (-43.5%) 0.01% -0.009 pp 0.00% -0.004 pp USD1.44 -12.5% 3 qtrs
78 QUBE RESEARCH & TECHNOLOGIES LTD 102.8K +102.8K (+100.0%) 129.5K +129.5K (+100.0%) 0.01% +0.013 pp 0.00% +0.000 pp USD1.26 +0.0% 1 qtrs NEW
79 POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY 102.4K +— (+0.0%) 129.0K -29.7K (-18.7%) 0.01% -0.002 pp 0.00% 0.000 pp USD1.49 -15.4% 5 qtrs
80 RPG FAMILY WEALTH ADVISORY, LLC 99.0K +— (+0.0%) 124.7K -28.7K (-18.7%) 0.01% -0.002 pp 0.03% -0.006 pp USD1.55 -18.7% 2 qtrs
81 AMERIPRISE FINANCIAL INC 96.2K +1.0K (+1.1%) 121.3K -26.4K (-17.9%) 0.01% -0.002 pp 0.00% +0.000 pp USD1.82 -30.8% 55 qtrs
82 SIMPLEX TRADING, LLC 93.9K -56.7K (-37.6%) 118.3K -114.7K (-49.2%) 0.01% -0.010 pp 0.00% 0.000 pp USD1.55 -18.7% 2 qtrs
83 SQUAREPOINT OPS LLC 92.5K +— (+0.0%) 116.6K -26.8K (-18.7%) 0.01% -0.002 pp 0.00% +0.000 pp USD1.47 -14.3% 5 qtrs
84 QUADRATURE CAPITAL LTD 91.7K +91.7K (+100.0%) 115.5K +115.5K (+100.0%) 0.01% +0.012 pp 0.00% +0.001 pp USD1.26 +0.0% 1 qtrs NEW
85 KLP KAPITALFORVALTNING AS 90.7K +16.7K (+22.6%) 114.3K -418.0 (-0.4%) 0.01% +0.001 pp 0.00% +0.000 pp USD1.43 -11.9% 5 qtrs
86 BNP PARIBAS ARBITRAGE, SNC 90.4K -27.9K (-23.6%) 113.9K -69.4K (-37.9%) 0.01% -0.006 pp 0.00% +0.000 pp USD1.65 -23.6% 51 qtrs
87 CAMBRIDGE INVESTMENT RESEARCH ADVISORS, INC. 89.7K -6.8K (-7.0%) 113.0K -37.0K (-24.7%) 0.01% -0.003 pp 0.00% 0.000 pp USD7.76 -83.8% 51 qtrs
88 HEADLANDS TECHNOLOGIES LLC 89.0K +43.7K (+96.6%) 112.1K +42.0K (+59.9%) 0.01% +0.005 pp 0.01% +0.004 pp USD1.45 -13.1% 8 qtrs
89 360 FINANCIAL, INC. 87.3K -4.0K (-4.4%) 110.0K -31.5K (-22.3%) 0.01% -0.002 pp 0.03% -0.017 pp USD1.82 -30.8% 25 qtrs
90 BREVAN HOWARD CAPITAL MANAGEMENT LP 85.3K +85.3K (+100.0%) 107.5K +107.5K (+100.0%) 0.01% +0.011 pp 0.00% +0.001 pp USD1.26 +0.0% 1 qtrs NEW
91 ADVISOR GROUP HOLDINGS, INC. 75.3K -11.5K (-13.2%) 94.9K -28.7K (-23.2%) 0.01% -0.003 pp 0.00% +0.000 pp USD1.57 -19.7% 24 qtrs
92 CWM, LLC 69.1K -55.6K (-44.6%) 87.0K -106.0K (-54.9%) 0.01% -0.010 pp 0.00% 0.000 pp USD1.57 -19.7% 6 qtrs
93 PENSIONMARK FINANCIAL GROUP, LLC 66.5K +25.9K (+63.8%) 83.8K +20.9K (+33.1%) 0.01% +0.003 pp 0.00% +0.000 pp USD1.40 -10.0% 6 qtrs
94 CASCADE FINANCIAL PARTNERS, LLC 66.5K +— (+0.0%) 83.8K -19.3K (-18.7%) 0.01% -0.001 pp 0.01% -0.003 pp USD1.31 -3.8% 8 qtrs
95 PICTET ASSET MANAGEMENT HOLDING SA 65.5K +— (+0.0%) 82.5K -19.0K (-18.7%) 0.01% -0.001 pp 0.00% +0.000 pp USD1.60 -21.3% 10 qtrs
96 PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO 61.5K +— (+0.0%) 77.0K -18.0K (-18.9%) 0.01% -0.001 pp 0.00% 0.000 pp USD13.21 -90.5% 43 qtrs
97 CETERA INVESTMENT ADVISERS 59.2K +112.0 (+0.2%) 74.5K -17.0K (-18.6%) 0.01% -0.001 pp 0.00% +0.000 pp USD1.77 -28.8% 21 qtrs
98 CAPITAL ADVISORS INC/OK 370.0K +— (+0.0%) 25.3K -11.4K (-31.0%) 0.05% -0.008 pp 0.00% 0.000 pp USD1.56 -19.2% 5 qtrs
Ownership breakdown by holder

ETF Ownership

Top ETFs holding this stock Held by 78 ETFs in our universe
# ETF Weight Est. AUM exposure TER
1 Invesco NASDAQ Future Gen 200 ETF QQQS 0.46% 101.4K 0.20%
2 VanEck Israel ETF ISRA 0.39% 592.2K 0.59%
3 State Street SPDR S&P Health Care Services ETF XHS 0.36% 723.0K 0.35%
4 iShares U.S. Healthcare Providers ETF IHF 0.09% 1.05M 0.38%
5 iShares MSCI USA Small-Cap Min Vol Factor ETF SMMV 0.08% 224.3K 0.20%
6 iShares Ageing Population UCITS ETF AGED.L 0.06% 555.5K 0.40%
7 Goldman Sachs ActiveBeta U.S. Small Cap Equity ETF GSSC 0.06% 608.7K 0.20%
8 iShares Biotechnology ETF IBB 0.04% 3.66M 0.44%
9 Vanguard Russell 2000 Value ETF VTWV 0.04% 481.0K 0.06%
10 iShares Russell 2000 Value ETF IWN 0.04% 5.11M 0.24%

Insider Activity

Insider Activity — Latest Quarter
Ratio by transactions
0.00
Bearish
Buys
2
Sells
0
Shares acquired
60.0K
Shares disposed
Cash buys
1.00
Cash sales
Net activity
+60,000
Insider buys vs sells (history) From To
Recent insider transactions

No recent insider transactions.

Executive team

Top executives
EBIT / Employee
-73.1K
Shares Outstanding
755.09M

Executive compensation

Executive compensation (annual)
# Year Executive Salary Bonus Stock award Option award Incentive Other Total % Stock-
based
Filing
1 2025 Phillip Frost, M.D. Chief Executive Officer 960.0K 480.0K 400.0K 14.0K 1.85M 21.57%
2 2025 Elias A. Zerhouni, M.D. President 900.0K 450.0K 400.0K 14.0K 1.76M 22.68%
3 2025 Jane H. Hsiao, Ph.D. Chief Technical Officer 900.0K 450.0K 400.0K 14.0K 1.76M 22.68%
4 2025 Steven D. Rubin Executive Vice President- Administration 810.0K 400.0K 350.0K 14.0K 1.57M 22.24%
5 2025 Adam Logal Senior Vice President and Chief Financial Officer 700.0K 475.0K 350.0K 14.0K 1.54M 22.74%
6 2024 Phillip Frost, M.D. Chief Executive Officer 960.0K 480.0K 710.0K 13.8K 2.16M 32.81%
7 2024 Jane H. Hsiao, Ph.D. Chief Technical Officer 900.0K 450.0K 710.0K 13.8K 2.07M 34.24%
8 2024 Elias A. Zerhouni, M.D. President 900.0K 450.0K 710.0K 13.8K 2.07M 34.24%
9 2024 Steven D. Rubin Executive Vice President- Administration 810.0K 400.0K 621.3K 13.8K 1.85M 33.67%
10 2024 Adam Logal Senior Vice President and Chief Financial Officer 700.0K 475.0K 621.3K 13.8K 1.81M 34.32%
11 2023 Phillip Frost, M.D. Chief Executive Officer 960.0K 480.0K 824.0K 13.2K 2.28M 36.18%
12 2023 Elias A. Zerhouni, M.D. President 900.0K 450.0K 824.0K 13.2K 2.19M 37.67%
13 2023 Jane H. Hsiao, Ph.D. Chief Technical Officer 900.0K 450.0K 824.0K 13.2K 2.19M 37.67%
14 2023 Steven D. Rubin Executive Vice President- Administration 810.0K 400.0K 721.0K 13.2K 1.94M 37.08%
15 2023 Adam Logal Senior Vice President and Chief Financial Officer 700.0K 375.0K 721.0K 13.2K 1.81M 39.85%
16 2022 Jon R. Cohen, M.D. Former Senior Vice President OPKO Health, Inc.; Former Executive Chairman-BioReference Health, LLC 600.0K 1.01M 1.61M 0.00%
17 2022 Phillip Frost, M.D. Chief Executive Officer 960.0K 12.2K 972.2K 0.00%
18 2022 Elias A. Zerhouni, M.D. President 900.0K 44.0K 12.2K 956.2K 4.60%
19 2022 Jane H. Hsiao, Ph.D. Chief Technical Officer 900.0K 12.2K 912.2K 0.00%
20 2022 Steven D. Rubin Executive Vice President- Administration 810.0K 12.2K 822.2K 0.00%
21 2022 Adam Logal Senior Vice President and Chief Financial Officer 700.0K 12.2K 712.2K 0.00%
22 2021 Jon R. Cohen, M.D. Senior Vice President-OPKO OPKO Health, Inc.; Executive Chairman-BioReference Health, LLC 575.0K 1.15M 1.70M 11.6K 3.43M 49.44%
23 2021 Jon R. Cohen, M.D. Former Senior Vice President OPKO Health, Inc.; Former Executive Chairman-BioReference Health, LLC 575.0K 1.15M 1.70M 11.6K 3.43M 49.44%
24 2021 Phillip Frost, M.D. Chief Executive Officer 960.0K 1.13M 11.6K 2.10M 53.81%
25 2021 Jane H. Hsiao, Ph.D. Chief Technical Officer 900.0K 1.13M 11.6K 2.04M 55.39%
26 2021 Adam Logal Senior Vice President and Chief Financial Officer 700.0K 200.0K 990.5K 11.6K 1.90M 52.07%
27 2021 Steven D. Rubin Executive Vice President- Administration 810.0K 990.5K 11.6K 1.81M 54.66%
28 2020 Jon R. Cohen, M.D. Senior Vice President-OPKO OPKO Health, Inc.; Executive Chairman-BioReference Health, LLC 575.0K 1.15M 1.76M 11.2K 3.49M 50.27%
29 2020 Jon R. Cohen, M.D. Former Senior Vice President OPKO Health, Inc.; Former Executive Chairman-BioReference Health, LLC 575.0K 1.15M 1.76M 11.2K 3.49M 50.27%
30 2020 Jon R. Cohen, M.D. Senior Vice President-OPKO OPKO Health, Inc.; Executive Chairman-BioReference Laboratories, Inc. 575.0K 1.15M 1.76M 11.2K 3.49M 50.27%
31 2020 Adam Logal Senior Vice President and Chief Financial Officer 600.0K 500.0K 441.0K 11.2K 1.55M 28.41%
32 2020 Phillip Frost, M.D. Chief Executive Officer 960.0K 567.0K 11.2K 1.54M 36.86%
33 2020 Jane H. Hsiao, Ph.D. Chief Technical Officer 900.0K 567.0K 11.2K 1.48M 38.36%
34 2020 Steven D. Rubin Executive Vice President- Administration 810.0K 441.0K 11.2K 1.26M 34.94%
35 2019 Jon R. Cohen, M.D. Senior Vice President-OPKO OPKO Health, Inc.; Executive Chairman-BioReference Health, LLC 575.0K 750.0K 961.0K 11.2K 2.30M 41.83%
36 2019 Jon R. Cohen, M.D. Senior Vice President-OPKO OPKO Health, Inc.; Executive Chairman-BioReference Laboratories, Inc. 575.0K 750.0K 961.0K 11.2K 2.30M 41.83%
37 2019 Phillip Frost, M.D. Chief Executive Officer 960.0K 434.0K 11.2K 1.41M 30.89%
38 2019 Jane H. Hsiao, Ph.D. Chief Technical Officer 900.0K 434.0K 11.2K 1.35M 32.26%
39 2019 Steven D. Rubin Executive Vice President- Administration 810.0K 310.0K 11.2K 1.13M 27.40%
40 2019 Adam Logal Senior Vice President and Chief Financial Officer 600.0K 310.0K 11.2K 921.2K 33.65%
41 2018 Phillip Frost, M.D. Chief Executive Officer 960.0K 1.07M 11.0K 2.04M 52.31%
42 2018 Jane H. Hsiao, Ph.D. Chief Technical Officer 900.0K 1.07M 11.0K 1.98M 53.90%
43 2018 Steven D. Rubin Executive Vice President- Administration 810.0K 639.0K 11.0K 1.46M 43.77%
44 2018 Adam Logal Senior Vice President and Chief Financial Officer 600.0K 639.0K 11.0K 1.25M 51.12%
45 2017 Phillip Frost, M.D. Chief Executive Officer 960.0K 10.8K 970.8K 0.00%
46 2017 Jane H. Hsiao, Ph.D. Chief Technical Officer 900.0K 15.8K 915.8K 0.00%
47 2017 Steven D. Rubin Executive Vice President- Administration 810.0K 10.8K 820.8K 0.00%
48 2017 Adam Logal Senior Vice President and Chief Financial Officer 600.0K 10.8K 610.8K 0.00%
49 2016 Phillip Frost, M.D. Chief Executive Officer 960.0K 2.09M 10.6K 3.06M 68.29%
50 2016 Jane H. Hsiao, Ph.D. Chief Technical Officer 900.0K 1.88M 70.6K 2.85M 65.96%
51 2016 Steven D. Rubin Executive Vice President-Administration 810.0K 1.88M 10.6K 2.70M 69.63%
52 2016 Steven D. Rubin Executive Vice President- Administration 810.0K 1.88M 10.6K 2.70M 69.63%
53 2016 Adam Logal Senior Vice President and Chief Financial Officer 600.0K 1.05M 10.6K 1.66M 63.12%
54 2015 Phillip Frost, M.D. Chief Executive Officer 525.0K 200.0K 3.10M 10.6K 3.84M 80.82%
55 2015 Jane H. Hsiao, Ph.D. Chief Technical Officer 515.0K 175.0K 2.79M 70.6K 3.55M 78.58%
56 2015 Steven D. Rubin Executive Vice President- Administration 504.0K 150.0K 2.79M 10.6K 3.45M 80.76%
57 2015 Steven D. Rubin Executive Vice President-Administration 504.0K 150.0K 2.79M 10.6K 3.45M 80.76%
58 2015 Adam Logal Senior Vice President and Chief Financial Officer 350.0K 100.0K 1.55M 10.6K 2.01M 77.09%
59 2014 Phillip Frost, M.D. Chief Executive Officer 500.0K 1.82M 290.4K 2.61M 69.77%
60 2014 Jane H. Hsiao, Ph.D. Chief Technical Officer 490.0K 1.60M 70.4K 2.16M 74.01%
61 2014 Steven D. Rubin Executive Vice President- Administration 480.0K 1.60M 10.4K 2.09M 76.48%
62 2014 Steven D. Rubin Executive Vice President-Administration 480.0K 1.60M 10.4K 2.09M 76.48%
63 2014 Adam Logal Senior Vice President and Chief Financial Officer 300.0K 1.14M 10.4K 1.45M 78.60%
64 2014 Juan F. Rodriguez Former Senior Vice President and Chief Financial Officer 74.0K 102.6K 176.6K 0.00%
65 2013 Jane H. Hsiao, Ph.D. Chief Technical Officer 482.3K 1.77M 240.2K 2.50M 71.05%
66 2013 Phillip Frost, M.D. Chief Executive Officer 492.3K 1.97M 10.2K 2.47M 79.68%
67 2013 Steven D. Rubin Executive Vice President- Administration 455.0K 1.77M 10.2K 2.24M 79.22%
68 2013 Steven D. Rubin Executive Vice President-Administration 455.0K 1.77M 10.2K 2.24M 79.22%
69 2013 Juan F. Rodriguez Former Senior Vice President and Chief Financial Officer 275.0K 10.2K 285.2K 0.00%
70 2012 Juan F. Rodriguez Former Senior Vice President and Chief Financial Officer 127.0K 711.0K 4.6K 842.6K 84.38%
71 2012 Phillip Frost, M.D. Chief Executive Officer 460.0K 9.8K 469.8K 0.00%
72 2012 Jane H. Hsiao, Ph.D. Chief Technical Officer 450.0K 9.8K 459.8K 0.00%
73 2012 Steven D. Rubin Executive Vice President- Administration 350.0K 9.8K 359.8K 0.00%
74 2012 Steven D. Rubin Executive Vice President-Administration 350.0K 9.8K 359.8K 0.00%
75 2011 Phillip Frost, M.D. Chief Executive Officer 460.0K 9.8K 469.8K 0.00%
76 2011 Jane H. Hsiao, Ph.D. Chief Technical Officer 450.0K 9.8K 459.8K 0.00%
77 2011 Steven D. Rubin Executive Vice President- Administration 350.0K 9.8K 359.8K 0.00%
78 2011 Steven D. Rubin Executive Vice President-Administration 350.0K 9.8K 359.8K 0.00%
79 2011 Rao Uppaluri, Ph.D. Senior Vice President and Chief Financial Officer 310.0K 9.8K 319.8K 0.00%
80 2010 Phillip Frost, M.D. Chief Executive Officer 439.2K 642.5K 9.8K 1.09M 58.86%
81 2010 Jane H. Hsiao, Ph.D. Chief Technical Officer 426.9K 642.5K 9.8K 1.08M 59.53%
82 2010 Steven D. Rubin Executive Vice President- Administration 342.3K 378.4K 9.8K 730.5K 51.80%
83 2010 Rao Uppaluri, Ph.D. Senior Vice President and Chief Financial Officer 304.6K 335.5K 9.8K 649.9K 51.62%
84 2009 Phillip Frost, M.D. Chief Executive Officer 337.5K 236.6K 54.8K 628.9K 37.62%
85 2009 Jane H. Hsiao, Ph.D. Chief Technical Officer 311.5K 202.8K 9.8K 524.2K 38.70%
86 2009 Steven D. Rubin Executive Vice President- Administration 311.5K 169.0K 9.8K 490.4K 34.47%
87 2009 Rao Uppaluri, Ph.D. Senior Vice President and Chief Financial Officer 285.6K 152.1K 9.8K 447.5K 33.99%
88 2008 Steven D. Rubin Executive Vice President-Administration 300.0K 414.1K 9.2K 723.3K 57.25%
89 2008 Phillip Frost, M.D. Chief Executive Officer 325.0K 291.3K 9.2K 625.5K 46.57%
90 2008 Jane H. Hsiao, Ph.D. Chief Technical Officer 300.0K 242.8K 9.2K 552.0K 43.98%
91 2008 Steven D. Rubin Executive Vice President- Administration 300.0K 194.2K 9.2K 503.4K 38.58%
92 2008 Rao Uppaluri, Ph.D. Senior Vice President and Chief Financial Officer 275.0K 169.9K 9.2K 454.1K 37.42%
93 2008 Naveed Shams, M.D., Ph.D. Senior Vice President- Research & Development and Chief Medical Officer 259.1K 71.4K 25.8K 356.4K 20.04%
94 2007 Phillip Frost, M.D. Chief Executive Officer 208.3K 3.02M 133.3K 3.36M 89.84%
95 2007 Dale R. Pfost Former President 134.8K 40.0K 2.12M 2.30M 0.00%
96 2007 Jane H. Hsiao, Ph.D. Chief Technical Officer 192.3K 1.96M 7.7K 2.16M 90.76%
97 2007 Steven D. Rubin Executive Vice President- Administration 192.3K 1.51M 7.7K 1.71M 88.31%
98 2007 Rao Uppaluri, Ph.D. Senior Vice President and Chief Financial Officer 176.3K 1.21M 7.1K 1.39M 86.83%
99 2007 Steven D. Rubin Executive Vice President-Administration 192.3K 251.8K 7.7K 451.3K 55.79%
100 2007 Adam Logal Executive Director of Finance, Chief Accounting Officer and Treasurer 106.6K 6.0K 185.4K 298.0K 62.22%
101 2007 John A. Paganelli Interim Chief Executive Officer 96.5K 59.8K 2.5K 158.8K 98.43%
102 2006 John A. Paganelli Interim Chief Executive Officer 25.0K 810.00 75.0K 100.0K 0.81%
103 2005 David E. Riggs CEO, Former President, CFO and Secretary 244.0K 244.0K 0.00%
104 2005 John A. Paganelli, Interim CEO 12.5K 20.0K 75.0K 107.5K 18.60%
105 2005 Dr. David Hostelley, CFO 15.0K 15.0K 0.00%
106 2004 David E. Riggs Former President, CFO 235.0K 75.0K 310.0K 24.19%
107 2004 David E. Riggs CEO, Former President, CFO and Secretary 235.0K 75.0K 310.0K 24.19%
108 2004 Ronald L. Goode, Ph.D. Former President, CEO 95.8K 95.8K 0.00%
109 2004 John A. Paganelli, Interim CEO 20.0K 75.0K 95.0K 21.05%
110 2003 Ronald L. Goode, Ph.D. former President, CEO 405.0K 105.0K 12.0K 522.0K 0.00%
111 2003 Ronald L. Goode, Ph.D. Former President, CEO 405.0K 105.0K 12.0K 522.0K 0.00%
112 2003 Ronald L. Goode, Ph.D former President, CEO 405.0K 105.0K 1.00 510.0K 0.00%
113 2003 David E. Riggs Vice President, Chief Business Officer, Chief Financial Officer & Secretary 190.6K 225.0K 415.6K 54.14%
114 2003 David E. Riggs CEO, Former President, CFO and Secretary 190.6K 225.0K 415.6K 54.14%
115 2003 David E. Riggs Former President, CFO 190.6K 225.0K 415.6K 54.14%
116 2002 Ronald L. Goode, Ph.D. former President, CEO 373.3K 105.0K 300.0K 12.0K 790.3K 37.96%
117 2002 Ronald L. Goode, Ph.D former President, CEO 373.3K 105.0K 300.0K 1.00 778.3K 38.54%
118 2001 Ronald L. Goode, Ph.D. former President, CEO 275.5K 400.0K 81.3K 756.8K 52.85%
CEO compensation breakdown

Proxy statements

Proxy statements (DEF 14A)
Filing date Form type Filing
2026-05-15 DEFA14A
2026-04-30 DEFA14A
2026-04-30 DEF 14A
2025-03-14 DEFA14A
2025-03-14 DEF 14A

Recent SEC filings

Recent SEC filings
Filing date Form type Filing
2026-05-15 DEFA14A
2026-04-30 DEFA14A
2026-04-30 DEF 14A
2026-04-30 ARS
2026-04-28 8-K
2026-04-28 10-Q
2026-03-20 4
2026-03-20 4
2026-03-20 3
2026-03-19 8-K

Executive team

NameTitleCompensationGender
Phillip Frost Chairman of the Board & CEO 1M
Elias Adam Zerhouni President & Vice Chairman of the Board 1M
Jane H. Hsiao Vice Chairman of the Board & Chief Technical Officer 1M
Steven D. Rubin Executive Vice President of Administration & Director 1M male
Adam E. Logal Senior Vice President, Chief Financial Officer, Chief Accounting Officer & Treasurer 1M male
Damien Burke Chief Executive Officer of EirGen Pharma male
Craig Allen Chief Executive Officer of Bioreference Health male
Gary J. Nabel Chief Information Officer & Director
Giovanni Abbadessa Chief Medical Officer of ModeX male
Hans Berner President of OPKO Health Iberoamerica male
Charles W. Bishop Chief Executive Officer of OPKO Renal
John R. Mascola Chief Scientific Officer of ModeX
ESG Rating
B
MEDICAL - DIAGNOSTICS & RESEARCH
2020
E (Environmental)
63.1 / 61.3
Company / Sector avg.
S (Social)
66.6 / 65.4
Company / Sector avg.
G (Governance)
70.6 / 64.9
Company / Sector avg.
ESG Total
66.8 / 63.8
Company / Sector avg.
ESG Score History MEDICAL - DIAGNOSTICS & RESEARCH
Benchmark vs Sector
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Market share among peers
Peer comparison — filtered group (TTM)
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Dividend history

Earnings history

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