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OnKure Therapeutics, Inc. (OKUR)

USD4.21 -0.01 (-0.24%)
US NASDAQ Healthcare Biotechnology
Address 6707 Winchester Circle 80301
Boulder, CO, US
CEO Nicholas A. Saccomano
IPO 2021-04-08
CIK 1637715 ISIN US68277Q1058

Explore sections of this company profile

Description

OnKure, Inc., established in 2011 and based in Boulder, Colorado, operates as a biopharmaceutical company primarily engaged in the creation and advancement of precise therapeutic agents for cancer. A core area of their research centers on developing highly selective inhibitors for histone deacetylases. Their current pipeline features OKI-179, an inhibitor specifically engineered to combat a wide spectrum of malignancies, including both blood-related cancers and solid tumor formations.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
USD4.21 -0.01 (-0.24%)
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Volume Profile
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Liquidity & share structure
Average Volume
304.1K
Beta
0.28
Float Shares
8.20M
Free Float %
60.0%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
-1.45% -15.25% -21.16% +40.66% +10.06% +16.90% +73.85% -95.83% -96.96% -97.74% -97.74%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
vs.
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Analyst Consensus (2 ratings, all time) Buy
Price Targets & DCF
Current price
4.21
Low 35.00 +731.4%
Consensus 35.00 +731.4%
Median 35.00 +731.4%
High 35.00 +731.4%
DCF (Unlevered) 4.23 +0.4%
DCF (Levered) 4.33 +2.8%

DCF figures are point estimates: small changes in growth or discount-rate assumptions move them materially. Read them as a reference, not a precise target.

Ratings Trend (MoM) 100% Bullish
Rating 2026-05 Change
Strong Buy 0 0
Buy 6 0
Hold 0 0
Sell 0 0
Strong Sell 0 0
Price Target Summary
Period # Analysts Avg Target
Last Month
Last Quarter
Last Year
All Time 1
35.00
+731.4%
Quality scores
Altman Z-Score
0.50
Distress
Piotroski F-Score
2 / 9
Weak
MOAT Score
3 / 10
No MOAT
Composite Rating
B
Overall Score
3 / 5
Medium
DCF Score
4 / 5
High
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
4 / 5
High
P/E Score
1 / 5
Low
P/Book Score
5 / 5
High
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
  • EPS growth Biotechnology: +29.7%
    -11.4% Q1'26: +6.7% (vs Q1'25)
  • FCF margin FCF growth · Biotechnology: +16.2%
  • EBIT margin Biotechnology: +0.0%
  • ROIC Biotechnology: -16.1%
    Q1'26: +850.5% (vs Q1'25)
  • Share dilution Biotechnology: -3.4%
    +1.3% Q1'26: +1.9% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    -0.01× Q1'26: -0.01× (vs Q1'25)
Valuation Multiples From To
Price Forecast (3Y) From To
Model
Adjust
P/E
Theoretical Return — If Invested Today

* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.

DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (0.36) × ERP
WACC = 99% × Ke + 1% × Kd (4.1%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Intrinsic value (base): 4.23 Current price: 4.21
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2024
actual
Dec 2025
actual
Dec 2026
2 Rev. Ana.
2 EPS Ana.
Dec 2027
2 Rev. Ana.
2 EPS Ana.
Dec 2028
2 Rev. Ana.
3 EPS Ana.
Dec 2029
1 EPS Ana.
Revenue
est: 666.7K (-100.0%)
500.0K
500.0K – 500.0K
-25.0% YoY
666.7K
666.7K – 666.7K
+33.3% YoY
1.00M
1.00M – 1.00M
+50.0% YoY
— – —
-100.0% YoY
EBITDA
-51.71M
-62.12M
— – —
— – —
— – —
— – —
EBIT
-52.37M
-62.95M
— – —
— – —
— – —
— – —
Net Income
-52.67M
est: -37.79M (-39.4%)
-59.52M
est: -61.43M (+3.1%)
-35.48M
-48.64M – -22.33M
+42.2% YoY
-28.72M
-31.35M – -26.10M
+19.0% YoY
-28.89M
-30.60M – -27.19M
-0.6% YoY
-21.36M
-21.36M – -21.36M
+26.1% YoY
SGA
10.59M
14.69M
— – —
— – —
— – —
— – —
EPS
-3.95
est: -2.83 (-39.4%)
-4.40
est: -4.56 (+3.5%)
-2.79
-3.60 – -1.65
+38.8% YoY
-2.13
-2.32 – -1.93
+23.7% YoY
-2.18
-2.26 – -2.01
-2.2% YoY
-1.58
-1.58 – -1.58
+27.4% YoY
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-11 B 3/5 4/5 1/5 1/5 4/5 1/5 5/5
2026-05-08 B 3/5 4/5 1/5 1/5 4/5 1/5 5/5
2026-05-07 B 3/5 4/5 1/5 1/5 4/5 1/5 5/5
2026-05-06 B 3/5 4/5 1/5 1/5 4/5 1/5 5/5
2026-05-05 B- 3/5 4/5 1/5 1/5 3/5 1/5 5/5
2026-05-04 B- 3/5 4/5 1/5 1/5 3/5 1/5 5/5
2026-05-01 B- 3/5 4/5 1/5 1/5 3/5 1/5 5/5
2026-04-30 B- 3/5 4/5 1/5 1/5 3/5 1/5 5/5
2026-04-29 B- 3/5 4/5 1/5 1/5 3/5 1/5 5/5
2026-04-28 B- 3/5 4/5 1/5 1/5 3/5 1/5 5/5
2026-04-27 B- 3/5 4/5 1/5 1/5 3/5 1/5 5/5
2026-04-24 B- 2/5 4/5 1/5 1/5 3/5 1/5 4/5
2026-04-23 C+ 2/5 4/5 1/5 1/5 2/5 1/5 4/5
2026-04-22 C+ 2/5 4/5 1/5 1/5 2/5 1/5 4/5
2026-04-21 C+ 2/5 4/5 1/5 1/5 2/5 1/5 4/5
2026-04-20 C+ 2/5 4/5 1/5 1/5 2/5 1/5 4/5
2026-04-17 C+ 2/5 4/5 1/5 1/5 2/5 1/5 4/5
2026-04-16 C+ 2/5 4/5 1/5 1/5 2/5 1/5 4/5

Owner Earnings

Owner's Earnings (history)

Owner's Earnings history not available.

Owner alignment
Owner's Earnings TTM
OE per share TTM
Owner's Yield
Maintenance CapEx ratio
Maint CapEx / Avg PPE

Ownership Overview

Ownership breakdown
At a glance
Institutional holders
1
Total invested
563.00
Insider transactions (90d)
0
Beneficial owners (>5%)
0
Beneficial owners (>5%)

No beneficial ownership filings recorded.

Institutional Activity (13F)

Institutional ownership trend From To
13F snapshot — 2026 Q1
Investors holding
1
-41 vs prev Q
New positions
0
Closed positions
41
Increased
0
Reduced
0
Put/Call ratio
0.00
Calls held
Puts held
Top institutional holders
# Investor Shares / Δ Mkt value / Δ Own% / Δ Weight% / Δ Avg px / Perf. Hold / Status
1 ACORN CAPITAL ADVISORS, LLC 2.84M +— (+0.0%) 8.24M +426.0K (+5.5%) 21.02% +0.000 pp 2.79% -1.174 pp USD5.54 -47.7% 5 qtrs
2 ADAR1 CAPITAL MANAGEMENT, LLC 1.01M +1.0M (+100.0%) 2.94M +2.9M (+100.0%) 7.51% +7.507 pp 0.22% +0.216 pp USD2.90 +0.0% 4 qtrs
3 PROSIGHT MANAGEMENT, LP 816.9K +549.0K (+204.9%) 2.37M +1.6M (+221.5%) 6.05% +4.064 pp 0.49% +0.318 pp USD3.44 -15.7% 5 qtrs
4 SHAY CAPITAL LLC 780.9K -137.1K (-14.9%) 2.26M -259.8K (-10.3%) 5.78% -1.015 pp 0.23% +0.015 pp USD2.83 +2.5% 5 qtrs
5 ROSALIND ADVISORS, INC. 730.5K +730.5K (+100.0%) 2.12M +2.1M (+100.0%) 5.41% +5.407 pp 0.74% +0.745 pp USD2.90 +0.0% 1 qtrs NEW
6 VESTAL POINT CAPITAL, LP 635.0K +— (+0.0%) 1.84M +95.3K (+5.5%) 4.70% +0.000 pp 0.06% -0.016 pp USD8.60 -66.3% 5 qtrs
7 VANGUARD GROUP INC 626.6K -51.6K (-7.6%) 1.82M -48.0K (-2.6%) 4.64% -0.382 pp 0.00% +0.000 pp USD8.60 -66.3% 5 qtrs
8 HIGHBRIDGE CAPITAL MANAGEMENT LLC 542.4K -107.9K (-16.6%) 1.57M -215.3K (-12.0%) 4.01% -0.798 pp 0.05% -0.028 pp USD6.24 -53.5% 5 qtrs
9 NEA MANAGEMENT COMPANY, LLC 478.5K +— (+0.0%) 1.39M +71.8K (+5.5%) 3.54% +0.000 pp 0.07% -0.002 pp USD8.60 -66.3% 5 qtrs
10 STEPSTONE GROUP LP 491.9K +— (+0.0%) 1.35M +— (+0.0%) 3.64% +0.000 pp 0.72% +0.088 pp USD8.60 -66.3% 5 qtrs
11 CANTOR FITZGERALD, L. P. 445.1K -46.8K (-9.5%) 1.29M -61.9K (-4.6%) 3.29% -0.346 pp 0.02% +0.006 pp USD2.99 -3.0% 5 qtrs
12 CARLYLE GROUP INC. 269.9K +— (+0.0%) 771.9K +29.7K (+4.0%) 2.00% +0.000 pp 0.01% -0.011 pp USD8.60 -66.3% 5 qtrs
13 RENAISSANCE TECHNOLOGIES LLC 247.4K +71.6K (+40.7%) 717.3K +234.0K (+48.4%) 1.83% +0.530 pp 0.00% +0.001 pp USD3.67 -21.0% 5 qtrs
14 CITADEL ADVISORS LLC 223.1K -793.5K (-78.1%) 647.1K -2.1M (-76.9%) 1.65% -5.874 pp 0.00% 0.000 pp USD8.48 -65.8% 5 qtrs
15 KOTLER KEVIN 197.7K +197.7K (+100.0%) 573.3K +573.3K (+100.0%) 1.46% +1.463 pp 0.13% +0.134 pp USD2.90 +0.0% 1 qtrs NEW
16 RANGELEY CAPITAL, LLC 145.0K -10.5K (-6.7%) 420.5K -7.1K (-1.7%) 1.07% -0.078 pp 0.35% -0.021 pp USD2.68 +8.2% 3 qtrs
17 AISLING CAPITAL MANAGEMENT LP 88.6K +— (+0.0%) 257.0K +13.3K (+5.5%) 0.66% +0.000 pp 0.05% +0.000 pp USD8.60 -66.3% 5 qtrs
18 GEODE CAPITAL MANAGEMENT, LLC 77.5K -7.4K (-8.7%) 224.7K -8.8K (-3.8%) 0.57% -0.055 pp 0.00% +0.000 pp USD8.12 -64.3% 5 qtrs
19 SPHERA FUNDS MANAGEMENT LTD. 60.5K +— (+0.0%) 175.3K +9.1K (+5.5%) 0.45% +0.000 pp 0.03% -0.001 pp USD8.60 -66.3% 5 qtrs
20 BLACKROCK, INC. 52.7K -512.2K (-90.7%) 152.8K -1.4M (-90.2%) 0.39% -3.791 pp 0.00% +0.000 pp USD3.37 -13.9% 5 qtrs
21 GSA CAPITAL PARTNERS LLP 45.9K -13.3K (-22.4%) 133.0K -30.0K (-18.4%) 0.34% -0.098 pp 0.01% -0.002 pp USD2.62 +10.7% 3 qtrs
22 ALDEBARAN CAPITAL, LLC 41.3K -2.7K (-6.2%) 119.7K -1.3K (-1.0%) 0.31% -0.020 pp 0.11% -0.004 pp USD8.60 -66.3% 5 qtrs
23 BARCLAYS PLC 27.2K +26.6K (+4,286.8%) 79.0K +77.3K (+4,525.4%) 0.20% +0.197 pp 0.00% +0.000 pp USD3.03 -4.3% 5 qtrs
24 TWO SIGMA ADVISERS, LP 26.6K +— (+0.0%) 77.2K +4.0K (+5.5%) 0.20% +0.000 pp 0.00% +0.000 pp USD6.51 -55.5% 5 qtrs
25 MORGAN STANLEY 25.0K +7.7K (+45.0%) 72.4K +25.1K (+52.9%) 0.18% +0.057 pp 0.00% +0.000 pp USD2.86 +1.4% 5 qtrs
26 HSBC HOLDINGS PLC 20.0K +20.0K (+100.0%) 57.7K +57.7K (+100.0%) 0.15% +0.148 pp 0.00% +0.000 pp USD2.90 +0.0% 1 qtrs NEW
27 NORTHERN TRUST CORP 19.9K -2.6K (-11.6%) 57.7K -4.2K (-6.8%) 0.15% -0.019 pp 0.00% +0.000 pp USD7.68 -62.2% 5 qtrs
28 BRIDGEWAY CAPITAL MANAGEMENT, LLC 19.5K +— (+0.0%) 56.6K +2.9K (+5.5%) 0.14% +0.000 pp 0.00% +0.000 pp USD4.30 -32.6% 4 qtrs
29 JANE STREET GROUP, LLC 19.4K +19.4K (+100.0%) 56.3K +56.3K (+100.0%) 0.14% +0.144 pp 0.00% +0.000 pp USD2.90 +0.0% 1 qtrs NEW
30 XTX TOPCO LTD 17.8K +17.8K (+100.0%) 51.6K +51.6K (+100.0%) 0.13% +0.132 pp 0.00% +0.001 pp USD2.90 +0.0% 5 qtrs
31 TWO SIGMA INVESTMENTS, LP 11.3K -14.1K (-55.5%) 32.8K -37.1K (-53.1%) 0.08% -0.105 pp 0.00% 0.000 pp USD4.30 -32.6% 4 qtrs
32 WELLS FARGO & COMPANY/MN 11.0K +1.5K (+15.8%) 31.9K +5.8K (+22.1%) 0.08% +0.011 pp 0.00% +0.000 pp USD3.78 -23.3% 5 qtrs
33 CITIGROUP INC 3.7K +405.0 (+12.2%) 10.8K +1.7K (+18.3%) 0.03% +0.003 pp 0.00% +0.000 pp USD2.96 -2.0% 5 qtrs
34 UBS GROUP AG 1.2K +1.0K (+489.3%) 3.5K +2.9K (+521.3%) 0.01% +0.007 pp 0.00% +0.000 pp USD3.75 -22.7% 5 qtrs
35 JPMORGAN CHASE & CO 545.00 +122.0 (+28.8%) 1.6K +418.0 (+35.9%) 0.00% +0.001 pp 0.00% +0.000 pp USD4.43 -34.5% 5 qtrs
36 FMR LLC 400.00 +350.0 (+700.0%) 1.2K +1.0K (+740.6%) 0.00% +0.003 pp 0.00% +0.000 pp USD2.88 +0.7% 2 qtrs
37 BNP PARIBAS ARBITRAGE, SNC 281.00 -83.0 (-22.8%) 815.00 -186.0 (-18.6%) 0.00% -0.001 pp 0.00% +0.000 pp USD6.76 -57.1% 5 qtrs
38 BANK OF AMERICA CORP /DE/ 141.00 -755.0 (-84.3%) 409.00 -2.1K (-83.4%) 0.00% -0.006 pp 0.00% +0.000 pp USD3.94 -26.4% 5 qtrs
39 TRUST CO OF TOLEDO NA /OH/ 136.00 +— (+0.0%) 394.00 +20.0 (+5.3%) 0.00% +0.000 pp 0.00% +0.000 pp USD2.39 +21.3% 3 qtrs
40 ADVISOR GROUP HOLDINGS, INC. 109.00 +9.0 (+9.0%) 316.00 +41.0 (+14.9%) 0.00% +0.000 pp 0.00% +0.000 pp USD2.43 +19.3% 5 qtrs
41 GROUP ONE TRADING, L.P. 56.00 +— (+0.0%) 162.00 +8.0 (+5.2%) 0.00% +0.000 pp 0.00% +0.000 pp USD8.59 -66.2% 5 qtrs
42 NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO 2.00 +2.0 (+100.0%) 6.00 +6.0 (+100.0%) 0.00% +0.000 pp 0.00% +0.000 pp USD2.50 +16.0% 1 qtrs NEW
43 MAI CAPITAL MANAGEMENT -6.0 (-100.0%) -17.0 (-100.0%) 0.00% +0.000 pp 0.00% +0.000 pp USD 5 qtrs SOLD
44 ROYAL BANK OF CANADA -190.0 (-100.0%) -1.0K (-100.0%) 0.00% -0.001 pp 0.00% +0.000 pp USD 3 qtrs SOLD
45 CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD. -2.3K (-100.0%) -6.2K (-100.0%) 0.00% -0.017 pp 0.00% -0.001 pp USD 5 qtrs SOLD
46 TANG CAPITAL MANAGEMENT LLC -116.4K (-100.0%) -320.1K (-100.0%) 0.00% -0.862 pp 0.00% -0.012 pp USD 5 qtrs SOLD
47 TOWER RESEARCH CAPITAL LLC (TRC) -1.9K (-100.0%) -5.3K (-100.0%) 0.00% -0.014 pp 0.00% 0.000 pp USD 5 qtrs SOLD
48 MIRAE ASSET GLOBAL INVESTMENTS CO., LTD. -497.0 (-100.0%) -1.4K (-100.0%) 0.00% -0.004 pp 0.00% +0.000 pp USD 5 qtrs SOLD
49 GF FUND MANAGEMENT CO. LTD. -271.0 (-100.0%) -745.0 (-100.0%) 0.00% -0.002 pp 0.00% +0.000 pp USD 5 qtrs SOLD
Ownership breakdown by holder

ETF Ownership

Top ETFs holding this stock Held by 38 ETFs in our universe
# ETF Weight Est. AUM exposure TER
1 iShares Micro-Cap ETF IWC 0.03% 374.7K 0.60%
2 iShares Russell 2000 Value ETF IWN 0.01% 963.9K 0.24%
3 Xtrackers Russell 2000 UCITS ETF 1C XRSU.L 0.00% 107.0K 0.30%
4 Global X - Russell 2000 ETF RSSL 0.00% 52.5K 0.08%
5 Invesco Russell 2000 UCITS ETF RTYS.L 0.00% 11.3K 0.25%
6 Avantis U.S. Small Cap Equity ETF AVSC 0.00% 99.0K 0.25%
7 iShares Russell 2000 BuyWrite ETF IWMW 0.00% 1.7K 0.39%
8 iShares Russell 2000 ETF IWM 0.00% 2.48M 0.19%
9 iShares U.S. Small Cap Index ETF (CAD-Hedged) XSU.TO 0.00% 16.2K 0.36%
10 ProShares - Ultra Russell2000 UWM 0.00% 4.4K 1.07%

Insider Activity

Insider Activity — Latest Quarter
Ratio by transactions
0.00
Bearish
Buys
4
Sells
0
Shares acquired
660.0K
Shares disposed
Cash buys
Cash sales
Net activity
+660,000
Insider buys vs sells (history) From To
Recent insider transactions From To
Date Person Role Transaction A/D Security Shares Price Value Owned after D/I Filing
2026-04-01 Saccomano Nicholas A Director / Officer A-Award A Employee Stock Option (right to buy) 330,000 4.07 1.34M 330,000 D
2026-04-01 Leverone Jason A. Officer A-Award A Employee Stock Option (right to buy) 110,000 4.07 447.7K 110,000 D
2026-04-01 Hartley Dylan Officer A-Award A Employee Stock Option (right to buy) 110,000 4.07 447.7K 110,000 D
2026-04-01 Agresta Samuel Officer A-Award A Employee Stock Option (right to buy) 110,000 4.07 447.7K 110,000 D
2026-03-31 Ratcliffe Liam Director A-Award A Stock Option (right to buy) 15,300 4.14 63.3K 15,300 D
2026-03-31 AI Biotechnology LLC 10% Owner Class A Common Stock 0 0.00 3,998,332 D
2026-03-23 Saccomano Nicholas A Director / Officer S-Sale D Class A Common Stock 86 4.16 357.46 7,333 D
2026-03-23 Leverone Jason A. Officer S-Sale D Class A Common Stock 301 4.16 1.3K 16,000 D
2025-12-31 Mathers Edward T Director A-Award A Class A Common Stock 3,911 0.00 15,310 D
2025-12-31 Manke Isaac Director A-Award A Class A Common Stock 5,258 0.00 20,583 D
2025-12-22 Saccomano Nicholas A Director / Officer S-Sale D Class A Common Stock 87 2.97 258.19 7,419 D
2025-12-22 Leverone Jason A. Officer S-Sale D Class A Common Stock 302 2.97 896.25 16,301 D
2025-09-30 Mathers Edward T Director A-Award A Class A Common Stock 4,125 0.00 11,399 D
2025-09-30 Manke Isaac Director A-Award A Class A Common Stock 5,545 0.00 15,325 D
2025-09-22 Saccomano Nicholas A Director / Officer S-Sale D Class A Common Stock 88 2.62 230.87 3,506 D
2025-09-22 Leverone Jason A. Officer S-Sale D Class A Common Stock 303 2.62 794.92 12,603 D
2025-06-30 Mathers Edward T Director A-Award A Class A Common Stock 4,694 0.00 7,274 D
2025-06-30 Manke Isaac Director A-Award A Class A Common Stock 6,311 0.00 9,780 D
2025-06-23 Saccomano Nicholas A Director / Officer S-Sale D Class A Common Stock 88 2.38 209.81 3,594 D
2025-06-23 Leverone Jason A. Officer S-Sale D Class A Common Stock 303 2.38 722.41 12,906 D
2025-05-28 Phillips Andrew John Director A-Award A Stock Option (right to buy) 7,650 2.44 18.7K 7,650 D
2025-05-28 Mathers Edward T Director A-Award A Stock Option (right to buy) 7,650 2.44 18.7K 7,650 D
2025-05-28 Manke Isaac Director A-Award A Stock Option (right to buy) 7,650 2.44 18.7K 7,650 D
2025-05-28 Jansen Valerie Malyvanh Director A-Award A Stock Option (right to buy) 7,650 2.44 18.7K 7,650 D
2025-05-28 GREY MICHAEL G Director A-Award A Stock Option (right to buy) 7,650 2.44 18.7K 7,650 D
2025-05-28 Carruthers R Michael Director A-Award A Stock Option (right to buy) 7,650 2.44 18.7K 7,650 D
2025-05-15 Cormorant Asset Management, LP 10% Owner S-Sale D Class A Common Stock 1,813,439 1.85 3.36M 0 I
2025-05-15 ACORN BIOVENTURES, L.P. 10% Owner P-Purchase A Common Stock 270,270 1.85 500.0K 1,709,944 D
2025-05-15 ACORN BIOVENTURES 2, L.P. 10% Owner Common Stock 0 0.00 1,129,730 D
2025-05-12 Cormorant Asset Management, LP 10% Owner S-Sale D Class A Common Stock 24,300 1.99 48.2K 1,813,439 I
2025-04-07 Saccomano Nicholas A Director / Officer S-Sale D Class A Common Stock 516 2.67 1.4K 3,682 D
2025-04-07 Leverone Jason A. Officer S-Sale D Class A Common Stock 1,844 2.67 4.9K 13,209 D
2025-04-04 Saccomano Nicholas A Director / Officer S-Sale D Class A Common Stock 358 3.33 1.2K 4,198 D
2025-04-04 Leverone Jason A. Officer S-Sale D Class A Common Stock 1,278 3.33 4.3K 15,053 D
2025-03-31 Mathers Edward T Director A-Award A Class A Common Stock 2,580 0.00 2,580 D
2025-03-31 Manke Isaac Director A-Award A Class A Common Stock 3,469 0.00 3,469 D
2025-01-27 Saccomano Nicholas A Director / Officer A-Award A Employee Stock Option (right to buy) 130,000 5.19 674.7K 130,000 D
2025-01-27 Leverone Jason A. Officer A-Award A Employee Stock Option (right to buy) 65,000 5.19 337.4K 65,000 D
2025-01-27 Hartley Dylan Officer A-Award A Employee Stock Option (right to buy) 45,000 5.19 233.6K 45,000 D
2025-01-27 Agresta Samuel Officer A-Award A Employee Stock Option (right to buy) 45,000 5.19 233.6K 45,000 D
2024-10-07 Leonard Braden Michael 10% Owner J-Other A Common Stock 345,739 0.00 345,739 I
2024-10-04 Saccomano Nicholas A 0 0.00 0
2024-10-04 Phillips Andrew John 0 0.00 0
2024-10-04 Mathers Edward T Director A-Award A Stock Option (right to buy) 15,300 18.20 278.5K 15,300 D
2024-10-04 Manke Isaac 0 0.00 0
2024-10-04 Leverone Jason A. 0 0.00 0
2024-10-04 Jansen Valerie Malyvanh 0 0.00 0
2024-10-04 Hartley Dylan Officer A-Award A Employee Stock Option (right to buy) 137,603 18.20 2.50M 137,603 D
2024-10-04 GREY MICHAEL G Director A-Award A Stock Option (right to buy) 15,300 18.20 278.5K 15,300 D
2024-10-04 Cormorant Asset Management, LP 10% Owner Class A Common Stock 0 0.00 1,837,739 I
2024-10-04 Carruthers R Michael 0 0.00 0
2024-10-04 Agresta Samuel Officer A-Award A Employee Stock Option (right to buy) 131,396 18.20 2.39M 131,396 D
2024-10-04 ACORN BIOVENTURES, L.P. 10% Owner Class A Common Stock 0 0.00 1,439,674 D

Executive team

Top executives
Shares Outstanding
13.67M

Executive compensation

Executive compensation (annual)

Executive compensation not available.

CEO compensation breakdown

No CEO compensation history available.

Proxy statements

Proxy statements (DEF 14A)
Filing date Form type Filing
2026-04-21 DEFA14A
2026-04-21 DEF 14A
2025-04-16 DEFA14A
2025-04-16 DEF 14A

Recent SEC filings

Recent SEC filings
Filing date Form type Filing
2026-05-05 8-K
2026-05-05 10-Q
2026-05-04 EFFECT
2026-04-24 S-3
2026-04-21 DEFA14A
2026-04-21 DEF 14A
2026-04-21 ARS
2026-04-07 SC 13G
2026-04-07 SC 13G
2026-04-07 SC 13G

Executive team

NameTitleCompensationGender
Nicholas A. Saccomano President, Chief Executive Officer & Director 858.0K
Samuel Agresta Chief Medical Officer 640.6K
Jason A. Leverone Chief Financial Officer 591.2K male
Isaac Manke Senior VP of Business Development & Director 60.5K
Roberta Alton Senior Vice President of Clinical Operations female
Rogan Nunn General Counsel & Secretary male
Mark L. Boys Senior Vice President of Discovery Chemistry
James Blake Senior Vice President of Computational Drug Discovery
Kevin S. Litwiler Senior Vice President of DMPK & Clinical Pharmacology
Dylan Hartley Chief Scientific Officer
ESG Rating
B
BIOTECHNOLOGY
2026
E (Environmental)
55.7 / 56.3
Company / Sector avg.
S (Social)
57.2 / 62.4
Company / Sector avg.
G (Governance)
62.5 / 60.9
Company / Sector avg.
ESG Total
58.5 / 59.9
Company / Sector avg.
ESG Score History BIOTECHNOLOGY
Benchmark vs Sector
Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend history

Earnings history

Earnings reports

Stock splits