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MediciNova, Inc. (MNOV)

USD1.40 +0.03 (+2.19%)
US NASDAQ Healthcare Biotechnology
Address 4275 Executive Square 92037
La Jolla, CA, US
CEO Yuichi Iwaki
IPO 2006-12-08
CIK 1226616 ISIN US58468P2065

Explore sections of this company profile

Also trades on NASDAQ Global Market · MNOV (USD) Tokyo Stock Exchange · 4875.T (JPY)
Description

MediciNova, Inc. is a biopharmaceutical firm dedicated to discovering and advancing innovative small molecule therapies for severe illnesses where current treatments are insufficient within the United States. Its robust development pipeline features MN-166 (ibudilast), an oral agent with both anti-inflammatory and neuroprotective properties, currently being investigated for a range of neurological conditions. These include primary and secondary progressive multiple sclerosis, amyotrophic lateral sclerosis, chemotherapy-induced peripheral neuropathy, degenerative cervical myelopathy, glioblastoma, and various forms of substance dependence and addiction. The company's portfolio also comprises MN-221 (bedoradrine), a selective beta-2-adrenergic receptor agonist aimed at treating acute asthma attacks; MN-001 (tipelukast), an orally available small molecule designed for fibrotic disorders like nonalcoholic steatohepatitis and idiopathic pulmonary fibrosis; and MN-029 (denibulin), a tubulin binding agent intended for solid tumor oncology. MediciNova has established strategic partnerships with companies such as Kissei Pharmaceutical Co., Ltd., Kyorin Pharmaceutical Co., Ltd., Angiogene Pharmaceuticals Ltd., and Meiji Seika Kaisha Ltd. Established in 2000, the company's headquarters are situated in La Jolla, California.

Market Cap & Enterprise Value
Merger & Acquisition History
Target company Ticker Date Filing
Avigen 4875 2009-09-17 View
Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
USD1.40 +0.03 (+2.19%)
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Volume Profile
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Liquidity & share structure
Average Volume
41.2K
Beta
0.62
Float Shares
42.26M
Free Float %
85.8%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
+2.19% -1.41% -0.71% -5.41% -9.68% +6.87% +2.19% -36.51% -66.35% -77.49% -87.21%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
vs.
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Analyst Consensus (4 ratings, all time) Buy
Price Targets & DCF
Current price
1.40
DCF (Unlevered) 0.61 -56.1%
DCF (Levered) 0.62 -55.6%

DCF figures are point estimates: small changes in growth or discount-rate assumptions move them materially. Read them as a reference, not a precise target.

Ratings Trend (MoM) 100% Bullish
Rating 2026-05 Change
Strong Buy 1 0
Buy 3 0
Hold 0 0
Sell 0 0
Strong Sell 0 0
Quality scores
Altman Z-Score
-13.75
Distress
Piotroski F-Score
2 / 9
Weak
MOAT Score
1 / 10
No MOAT
Composite Rating
B-
Overall Score
2 / 5
Medium
DCF Score
3 / 5
Medium
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
4 / 5
High
P/E Score
1 / 5
Low
P/Book Score
4 / 5
High
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
  • EPS growth Biotechnology: +29.7%
    -4.4% Q1'26: +14.4% (vs Q1'25)
  • FCF margin FCF growth · Biotechnology: +16.2%
    -2,811.6% Q1'26: -1.1% (vs Q1'25)
  • EBIT margin Biotechnology: +0.0%
    -2,927.3% Q1'26: +0.0% (vs Q1'25)
  • ROIC Biotechnology: -16.1%
    -109.3% Q1'26: +0.0% (vs Q1'25)
  • Share dilution Biotechnology: -3.4%
    +0.0% Q1'26: +0.4% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    -0.02×
Valuation Multiples From To
Price Forecast (3Y) From To
Model
Adjust
P/E
Theoretical Return — If Invested Today

* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.

DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (0.63) × ERP
WACC = 100% × Ke + 0% × Kd (4.1%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Intrinsic value (base): 0.61 Current price: 1.40
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2019
actual
Dec 2021
actual
Dec 2023
actual
Dec 2024
actual
Dec 2025
actual
Dec 2026
3 Rev. Ana.
2 EPS Ana.
Dec 2027
2 Rev. Ana.
2 EPS Ana.
Dec 2028
3 Rev. Ana.
3 EPS Ana.
Dec 2029
2 Rev. Ana.
1 EPS Ana.
Dec 2030
1 Rev. Ana.
1 EPS Ana.
Revenue
est: 19.13M (-100.0%)
4.04M
est: 4.01M (+0.6%)
1.00M
est: 1.00M (+0.0%)
est: 134.6K (-100.0%)
409.7K
est: 150.0K (+173.1%)
166.7K
166.7K – 166.7K
+11.1% YoY
700.0K
700.0K – 700.0K
+320.0% YoY
42.69M
42.69M – 42.69M
+5,998.6% YoY
97.61M
97.61M – 97.61M
+128.6% YoY
202.19M
202.19M – 202.19M
+107.1% YoY
EBITDA
-14.01M
est: 3.83M (-466.0%)
-10.19M
est: 802.5K (-1,369.7%)
-9.88M
est: -200.0K (-4,840.0%)
-12.65M
est: -26.9K (-46,908.6%)
-11.97M
est: -30.0K (-39,807.5%)
-33.3K
-33.3K – -33.3K
-11.1% YoY
-140.0K
-140.0K – -140.0K
-320.0% YoY
-8.54M
-8.54M – -8.54M
-5,998.7% YoY
-19.52M
-19.52M – -19.52M
-128.6% YoY
-40.44M
-40.44M – -40.44M
-107.1% YoY
EBIT
-14.03M
est: 3.83M (-466.7%)
-10.22M
est: 802.5K (-1,372.9%)
-9.90M
est: -200.0K (-4,850.2%)
-12.68M
est: -26.9K (-46,986.9%)
-11.99M
est: -30.0K (-39,874.5%)
-33.3K
-33.3K – -33.3K
-11.1% YoY
-140.0K
-140.0K – -140.0K
-320.0% YoY
-8.54M
-8.54M – -8.54M
-5,998.7% YoY
-19.52M
-19.52M – -19.52M
-128.6% YoY
-40.44M
-40.44M – -40.44M
-107.1% YoY
Net Income
-12.94M
est: -17.09M (+24.3%)
-10.13M
est: -12.42M (+18.4%)
-8.57M
est: -8.17M (-4.9%)
-11.05M
est: -10.79M (-2.4%)
-12.00M
est: -18.64M (+35.6%)
-14.96M
-14.96M – -14.96M
+19.7% YoY
-19.63M
-19.63M – -19.63M
-31.1% YoY
-10.66M
-21.59M – 14.23M
+45.7% YoY
32.55M
32.55M – 32.55M
+405.2% YoY
78.50M
78.50M – 78.50M
+141.2% YoY
SGA
7.95M
est: 36.96M (-78.5%)
5.72M
est: 7.75M (-26.3%)
5.24M
est: 4.74M (+10.6%)
5.48M
est: 637.8K (+759.3%)
6.16M
est: 710.8K (+766.5%)
789.8K
789.8K – 789.8K
+11.1% YoY
3.32M
3.32M – 3.32M
+320.0% YoY
202.29M
202.29M – 202.29M
+5,998.6% YoY
462.54M
462.54M – 462.54M
+128.6% YoY
958.09M
958.09M – 958.09M
+107.1% YoY
EPS
-0.30
est: -0.35 (+13.9%)
-0.21
est: -0.25 (+17.1%)
-0.17
est: -0.17 (-2.1%)
-0.23
est: -0.22 (-4.5%)
-0.24
est: -0.38 (+36.8%)
-0.31
-0.31 – -0.31
+19.7% YoY
-0.40
-0.40 – -0.40
-31.1% YoY
-0.11
-0.44 – 0.29
+72.5% YoY
0.66
0.66 – 0.66
+703.0% YoY
1.60
1.60 – 1.60
+141.2% YoY
Recent Grade Changes (3M)
Date Firm Previous New Grade Action
2026-05-04 D. Boral Capital Buy Buy Maintain
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-12 B- 2/5 3/5 1/5 1/5 4/5 1/5 4/5
2026-05-11 B- 2/5 3/5 1/5 1/5 4/5 1/5 4/5
2026-05-08 B- 2/5 3/5 1/5 1/5 4/5 1/5 4/5
2026-05-07 B- 2/5 3/5 1/5 1/5 4/5 1/5 4/5
2026-05-06 B- 2/5 3/5 1/5 1/5 4/5 1/5 4/5
2026-05-05 C+ 2/5 3/5 1/5 1/5 3/5 1/5 4/5
2026-05-04 C+ 2/5 3/5 1/5 1/5 3/5 1/5 4/5
2026-05-01 C+ 2/5 3/5 1/5 1/5 3/5 1/5 4/5
2026-04-30 C+ 2/5 3/5 1/5 1/5 3/5 1/5 4/5
2026-04-29 C+ 2/5 3/5 1/5 1/5 3/5 1/5 4/5
2026-04-28 C+ 2/5 3/5 1/5 1/5 3/5 1/5 4/5
2026-04-27 C+ 2/5 3/5 1/5 1/5 3/5 1/5 4/5
2026-04-24 C+ 2/5 3/5 1/5 1/5 3/5 1/5 4/5
2026-04-23 C+ 2/5 3/5 1/5 1/5 2/5 1/5 4/5
2026-04-22 C+ 2/5 3/5 1/5 1/5 2/5 1/5 4/5
2026-04-21 C+ 2/5 3/5 1/5 1/5 2/5 1/5 4/5
2026-04-20 C+ 2/5 3/5 1/5 1/5 2/5 1/5 4/5
2026-04-17 C+ 2/5 3/5 1/5 1/5 2/5 1/5 4/5
2026-04-16 C+ 2/5 3/5 1/5 1/5 2/5 1/5 4/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
-9.81M
OE per share TTM
-0.20
Owner's Yield
-14.48%
Maintenance CapEx ratio
Maint CapEx / Avg PPE
55.4%

Ownership Overview

Ownership breakdown
At a glance
Institutional holders
10
Total invested
3.31M
Insider transactions (90d)
0
Beneficial owners (>5%)
36
Beneficial owners (>5%)
# Reporting person Amount owned % of class Sole voting Shared voting Sole dispositive Shared dispositive Type Citizenship Filing date SEC filing
1 Essex Woodlands Health Ventures Fund VI, L.P. 11.70M 11.84% PN : 2006-02-13
2 Essex Woodlands Health Ventures VI, L.L.C. 11.70M 11.84% OO : 2006-02-13
3 Essex Woodlands Health Ventures VI, L.P. 11.70M 11.84% OO : 2006-02-13
4 Immanuel Thangaraj 11.70M 11.84% IN : 2006-02-13
5 Mark Pacala 11.70M 11.84% IN : 2006-02-13
6 Martin P. Sutter 11.70M 11.84% IN : 2006-02-13
7 Petri Vainio, MD, Ph.D. 11.70M 11.84% IN : 2006-02-13
8 3D Investment Partners Pte. Ltd. 5.50M 11.30% 5.50M 5.50M IA, OO Singapore 2021-01-21
9 3D Opportunity Master Fund 5.50M 11.30% 5.50M 5.50M OO Cayman Islands 2021-01-21
10 Edward C. Johnson 3d 3.51M 11.73% 3.51M IN Delaware 2015-09-10
11 Hajime Satomi 2.22M 10.00% 2.22M 2.22M IN Japan 2013-05-20
12 Samurai Investments San Diego LLC 1.75M 8.00% 1.75M 1.75M OO Japan 2013-05-20
13 Inc. 1.46M 10.70% 1.46M CO Illinois 2009-12-24
14 N. Lampert 1.46M 10.70% 1.46M IN Illinois 2009-12-24
15 Partners L.P. 1.46M 10.70% 1.46M IA Illinois 2009-12-24
16 (1) BlackRock, Inc. 1.13M 2.30% 1.13M 1.13M HC Delaware 2021-07-12
17 Cummings Bay Capital Management GP, LLC 913.0K 5.60% 913.0K HC, OO Delaware 2012-02-09
18 Cummings Bay Capital Management, L.P. 913.0K 5.60% 913.0K IA, PN Delaware 2012-02-09
19 Highland Capital Management Services, Inc. 913.0K 5.60% 913.0K HC, CO Delaware 2012-02-09
20 James D. Dondero 913.0K 5.60% 913.0K HC, IN United States 2012-02-09
21 Southpaw Credit Opportunity Master Fund LP 873.1K 6.60% 873.1K 873.1K PN Cayman Islands 2011-01-19
22 Pyxis Capital, L.P. (f/k/a Highland Funds Asset Management, L.P.) 843.4K 5.20% 843.4K IA, PN Delaware 2012-02-09
23 Pyxis Long/Short Healthcare Fund (f/k/a Highland Long/Short Healthcare Fund) 843.4K 5.20% 843.4K 843.4K IV, OO Delaware 2012-02-09
24 Strand Advisors XVI, Inc. 843.4K 5.20% 843.4K HC, CO Delaware 2012-02-09
25 Investments, L.L.C. 821.2K 6.30% 821.2K OO Illinois 2009-12-24
26 Yuichi Iwaki 767.7K 6.40% 767.7K 767.7K IN Japan 2008-02-11
27 JAFCO G-9(A) Venture Capital Investment Limited Partnership 415.7K 4.21% 415.7K 415.7K PN Citizenship or Place of Organization 2007-02-14
28 Value Fund, L.P. 325.4K 2.60% 325.4K PN Illinois 2009-12-24
29 JAFCO G-9(B) Venture Capital Investment Limited Partnership 278.0K 2.81% 278.0K 278.0K PN Citizenship or Place of Organization 2007-02-14
30 Value Fund II, L.P. 224.9K 1.80% 224.9K PN Illinois 2009-12-24
31 10, L.L.C. 84.1K 1.00% 84.1K OO Illinois 2009-12-24
32 Howard Golden 0.00% IN : 2012-01-23
33 Kevin Wyman 0.00% IN : 2012-01-23
34 Southpaw Asset Management LP 0.00% PN : 2012-01-23
35 Southpaw Credit Opportunity Master Fund L.P. 0.00% PN : 2012-01-23
36 Southpaw Holdings LLC 0.00% OO : 2012-01-23

Institutional Activity (13F)

Institutional ownership trend From To
13F snapshot — 2026 Q1
Investors holding
10
-23 vs prev Q
New positions
3
Closed positions
26
Increased
3
Reduced
5
Put/Call ratio
0.00
Calls held
Puts held
Top institutional holders
# Investor Shares / Δ Mkt value / Δ Own% / Δ Weight% / Δ Avg px / Perf. Hold / Status
1 ESSEX WOODLANDS MANAGEMENT, INC. 1.11M +— (+0.0%) 1.45M +44.2K (+3.1%) 2.25% +0.000 pp 0.46% -0.002 pp USD2.64 -50.4% 51 qtrs
2 VANGUARD GROUP INC 705.6K +5.2K (+0.7%) 924.4K +41.9K (+4.7%) 1.44% +0.011 pp 0.00% +0.000 pp USD5.66 -76.9% 64 qtrs
3 BLACKROCK, INC. 705.0K +6.0K (+0.9%) 923.5K +35.8K (+4.0%) 1.44% +0.012 pp 0.00% +0.000 pp USD2.09 -37.3% 6 qtrs
4 CITIGROUP INC 635.7K +41.7K (+7.0%) 832.8K +84.3K (+11.3%) 1.30% +0.085 pp 0.00% +0.000 pp USD3.97 -67.0% 40 qtrs
5 DRW SECURITIES, LLC 3.8K +3.8K (+100.0%) 820.8K +820.8K (+100.0%) 0.01% +0.008 pp 0.02% +0.022 pp USD1.31 +0.0% 1 qtrs NEW
6 GEODE CAPITAL MANAGEMENT, LLC 529.6K -119.0 (0.0%) 693.9K +26.3K (+3.9%) 1.08% 0.000 pp 0.00% +0.000 pp USD5.56 -76.4% 59 qtrs
7 UBS GROUP AG 225.7K +3.4K (+1.5%) 295.6K +13.3K (+4.7%) 0.46% +0.007 pp 0.00% +0.000 pp USD2.09 -37.3% 8 qtrs
8 RENAISSANCE TECHNOLOGIES LLC 196.8K +4.3K (+2.2%) 257.8K +13.3K (+5.5%) 0.40% +0.009 pp 0.00% +0.000 pp USD2.81 -53.4% 25 qtrs
9 STATE STREET CORP 193.7K +19.1K (+10.9%) 253.7K +33.8K (+15.3%) 0.39% +0.039 pp 0.00% +0.000 pp USD6.11 -78.6% 40 qtrs
10 JANE STREET GROUP, LLC 163.1K +163.1K (+100.0%) 213.7K +213.7K (+100.0%) 0.33% +0.333 pp 0.00% +0.000 pp USD1.31 +0.0% 1 qtrs NEW
11 NORTHERN TRUST CORP 133.2K -1.6K (-1.2%) 174.4K +3.3K (+1.9%) 0.27% -0.003 pp 0.00% +0.000 pp USD6.92 -81.1% 51 qtrs
12 BANK OF NEW YORK MELLON CORP 96.2K +— (+0.0%) 126.0K +3.8K (+3.1%) 0.20% +0.000 pp 0.00% +0.000 pp USD7.01 -81.3% 40 qtrs
13 BRIDGEWAY CAPITAL MANAGEMENT, LLC 76.0K +— (+0.0%) 99.6K +3.8K (+4.0%) 0.16% +0.000 pp 0.00% +0.000 pp USD4.05 -67.7% 20 qtrs
14 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 71.5K +— (+0.0%) 93.7K +3.6K (+4.0%) 0.15% +0.000 pp 0.00% +0.000 pp USD1.44 -9.0% 39 qtrs
15 DIMENSIONAL FUND ADVISORS LP 65.0K -1.2K (-1.8%) 85.2K +1.7K (+2.1%) 0.13% -0.002 pp 0.00% +0.000 pp USD2.67 -50.9% 24 qtrs
16 SBI SECURITIES CO., LTD. 45.2K -305.0 (-0.7%) 59.3K +1.4K (+2.5%) 0.09% -0.001 pp 0.00% +0.000 pp USD2.04 -35.8% 5 qtrs
17 TWO SIGMA INVESTMENTS, LP 39.7K +39.7K (+100.0%) 52.1K +52.1K (+100.0%) 0.08% +0.081 pp 0.00% +0.000 pp USD1.31 +0.0% 1 qtrs NEW
18 BARCLAYS PLC 39.4K -43.4K (-52.4%) 51.6K -122.3K (-70.3%) 0.08% -0.089 pp 0.00% +0.000 pp USD3.25 -59.7% 38 qtrs
19 SCHONFELD STRATEGIC ADVISORS LLC 36.0K +1.4K (+4.0%) 47.2K +3.2K (+7.3%) 0.07% +0.003 pp 0.00% +0.000 pp USD2.61 -49.8% 17 qtrs
20 BANK OF AMERICA CORP /DE/ 30.0K -61.5K (-67.2%) 39.3K -76.9K (-66.2%) 0.06% -0.125 pp 0.00% +0.000 pp USD2.41 -45.6% 51 qtrs
21 LANTERN WEALTH ADVISORS, LLC 30.0K +30.0K (+100.0%) 39.3K +39.3K (+100.0%) 0.06% +0.061 pp 0.02% +0.021 pp USD1.31 +0.0% 1 qtrs NEW
22 CITADEL ADVISORS LLC 28.7K -44.2K (-60.6%) 37.6K -54.2K (-59.0%) 0.06% -0.090 pp 0.00% +0.000 pp USD1.27 +3.1% 2 qtrs
23 GOLDMAN SACHS GROUP INC 26.5K +26.5K (+100.0%) 34.7K +34.7K (+100.0%) 0.05% +0.054 pp 0.00% +0.000 pp USD1.31 +0.0% 1 qtrs NEW
24 SUSQUEHANNA INTERNATIONAL GROUP, LLP 22.8K -100.1K (-81.5%) 29.8K -125.0K (-80.7%) 0.05% -0.204 pp 0.00% +0.000 pp USD2.07 -36.7% 29 qtrs
25 STONEX GROUP INC. 19.2K +19.2K (+100.0%) 25.2K +25.2K (+100.0%) 0.04% +0.039 pp 0.00% +0.001 pp USD1.31 +0.0% 1 qtrs NEW
26 TWO SIGMA ADVISERS, LP 13.5K +13.5K (+100.0%) 17.7K +17.7K (+100.0%) 0.03% +0.028 pp 0.00% +0.000 pp USD1.31 +0.0% 1 qtrs NEW
27 BUCKINGHAM STRATEGIC PARTNERS 10.0K +10.0K (+100.0%) 13.1K +13.1K (+100.0%) 0.02% +0.020 pp 0.00% +0.000 pp USD1.31 +0.0% 1 qtrs NEW
28 HANTZ FINANCIAL SERVICES, INC. 4.3K +— (+0.0%) 6.0K +1.0K (+20.0%) 0.01% +0.000 pp 0.00% +0.000 pp USD1.85 -29.2% 9 qtrs
29 MORGAN STANLEY 2.0K +— (+0.0%) 2.6K +80.0 (+3.1%) 0.00% +0.000 pp 0.00% +0.000 pp USD1.27 +3.1% 4 qtrs
30 TOWER RESEARCH CAPITAL LLC (TRC) 1.8K -363.0 (-16.4%) 2.4K -387.0 (-13.8%) 0.00% -0.001 pp 0.00% +0.000 pp USD1.96 -33.2% 23 qtrs
31 JPMORGAN CHASE & CO 576.00 +500.0 (+657.9%) 755.00 +659.0 (+686.5%) 0.00% +0.001 pp 0.00% +0.000 pp USD1.37 -4.4% 34 qtrs
32 NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO 305.00 +— (+0.0%) 400.00 +13.0 (+3.4%) 0.00% +0.000 pp 0.00% +0.000 pp USD5.05 -74.1% 20 qtrs
33 ADVISOR GROUP HOLDINGS, INC. 66.00 +66.0 (+100.0%) 86.00 +86.0 (+100.0%) 0.00% +0.000 pp 0.00% +0.000 pp USD1.30 +0.8% 1 qtrs NEW
34 FMR LLC -50.0 (-100.0%) -63.0 (-100.0%) 0.00% 0.000 pp 0.00% +0.000 pp USD 2 qtrs SOLD
Ownership breakdown by holder

ETF Ownership

Top ETFs holding this stock Held by 2 ETFs in our universe
# ETF Weight Est. AUM exposure TER
1 iShares Micro-Cap ETF IWC 0.01% 221.0K 0.60%
2 Vanguard Extended Market ETF VXF 0.00% 809.6K 0.05%

Insider Activity

Insider Activity — Latest Quarter
Ratio by transactions
0.00
Bearish
Buys
7
Sells
0
Shares acquired
973.5K
Shares disposed
Cash buys
Cash sales
Net activity
+973,500
Insider buys vs sells (history) From To
Recent insider transactions From To
Date Person Role Transaction A/D Security Shares Price Value Owned after D/I Filing
2026-01-16 Matsuda Kazuko Officer A-Award A Employee Stock Option (Right to Buy) 350,000 2.10 735.0K 350,000 D
2026-01-16 IWAKI YUICHI Officer A-Award A Employee Stock Option (Right to Buy) 450,000 2.10 945.0K 450,000 D
2025-06-17 Nagao Hideki Director A-Award A Stock Option (Right to Buy) 20,000 1.26 25.2K 20,000 D
2025-06-17 Lemerond Nicole Director A-Award A Stock Option (Right to Buy) 20,000 1.26 25.2K 20,000 D
2025-06-17 BEAVER CAROLYN Director A-Award A Stock Option (Right to Buy) 20,000 1.26 25.2K 20,000 D
2025-02-12 Nagao Hideki Director A-Award A Stock Option (Right to Buy) 24,500 1.84 45.1K 24,500 D
2025-02-12 Matsuda Kazuko Director / Officer A-Award A Employee Stock Option (Right to Buy) 100,000 1.84 184.0K 100,000 D
2025-02-12 Lemerond Nicole Director A-Award A Stock Option (Right to Buy) 24,500 1.84 45.1K 24,500 D
2025-02-12 IWAKI YUICHI Director / Officer A-Award A Employee Stock Option (Right to Buy) 100,000 1.84 184.0K 100,000 D
2025-02-12 BEAVER CAROLYN Director A-Award A Stock Option (Right to Buy) 24,500 1.84 45.1K 24,500 D
2025-01-07 Matsuda Kazuko Director / Officer A-Award A Employee Stock Option (Right to Buy) 300,000 1.52 456.0K 300,000 D
2025-01-07 IWAKI YUICHI Director / Officer A-Award A Employee Stock Option (Right to Buy) 400,000 1.52 608.0K 400,000 D
2024-06-11 Nagao Hideki Director A-Award A Stock Option (Right to Buy) 20,000 1.34 26.8K 20,000
2024-06-11 Lemerond Nicole Director A-Award A Stock Option (Right to Buy) 20,000 1.34 26.8K 20,000
2024-06-11 BEAVER CAROLYN Director A-Award A Stock Option (Right to Buy) 20,000 1.34 26.8K 20,000
2024-01-09 OBrien Geoffrey Officer A-Award A Employee Stock Option (Right to Buy) 84,000 2.40 201.6K 84,000
2024-01-09 Matsuda Kazuko Director / Officer A-Award A Employee Stock Option (Right to Buy) 157,500 2.40 378.0K 157,500
2024-01-09 IWAKI YUICHI Director / Officer A-Award A Employee Stock Option (Right to Buy) 210,000 2.40 504.0K 210,000
2023-08-04 Lemerond Nicole Director A-Award A Stock Option (Right to Buy) 18,333 2.47 45.3K 18,333
2023-06-13 Nagao Hideki Director A-Award A Stock Option (Right to Buy) 20,000 2.23 44.6K 20,000
2023-06-13 BEAVER CAROLYN Director A-Award A Stock Option (Right to Buy) 20,000 2.23 44.6K 20,000
2023-01-23 OBrien Geoffrey Officer A-Award A Employee Stock Option (Right to Buy) 76,950 0.00 76,950
2023-01-23 Matsuda Kazuko Officer A-Award A Employee Stock Option (Right to Buy) 149,625 0.00 149,625
2023-01-23 IWAKI YUICHI Officer A-Award A Employee Stock Option (Right to Buy) 235,125 0.00 235,125
2022-11-28 Nagao Hideki Director S-Sale D Common Stock 6,754 2.25 15.2K 0
2022-11-22 Nagao Hideki Director S-Sale D Common Stock 218 2.13 464.34 6,754
2022-11-21 Nagao Hideki Director S-Sale D Common Stock 5,365 2.18 11.7K 6,972
2022-11-17 Nagao Hideki Director S-Sale D Common Stock 309 2.18 673.62 12,337
2022-06-16 Nagao Hideki Director A-Award A Stock Option (Right to Buy) 20,000 0.00 20,000
2022-06-16 Kruger Jason J Officer 0 0.00 0
2022-06-16 BEAVER CAROLYN Director A-Award A Stock Option (Right to Buy) 20,000 2.51 50.2K 20,000
2022-01-27 OBrien Geoffrey Officer A-Award A Employee Stock Option (Right to Buy) 99,000 5.92 586.1K 99,000
2022-01-27 Matsuda Kazuko Director / Officer A-Award A Employee Stock Option (Right to Buy) 192,500 5.92 1.14M 192,500
2022-01-27 IWAKI YUICHI Director / Officer A-Award A Employee Stock Option (Right to Buy) 302,500 5.92 1.79M 302,500
2021-08-23 Matsuda Kazuko Director / Officer M-Exempt A Common Stock 60,000 2.30 138.0K 322,996
2021-08-01 Paulin Douglas Officer 0 0.00 0
2021-07-09 IWAKI YUICHI Director / Officer M-Exempt D Employee Stock option (Right to Buy) 39,583 2.54 100.5K 0
2021-06-24 Matsuda Kazuko Director / Officer M-Exempt A Common Stock 56,250 2.46 138.4K 262,996
2021-06-16 Nagao Hideki Director A-Award A Stock Option (Right to Buy) 20,000 3.95 79.0K 20,000
2021-06-16 BEAVER CAROLYN Director A-Award A Stock Option (Right to Buy) 20,000 3.95 79.0K 20,000
2021-05-19 OBrien Geoffrey Officer M-Exempt A Common Stock 11,318 2.46 27.8K 48,318
2021-04-22 Gaeta Federico C.A. Officer D Employee Stock Option (Right to Buy) 20,000 5.42 108.4K 0
2021-03-11 Nagao Hideki Director S-Sale D Common Stock 2,354 7.40 17.4K 12,646
2021-02-25 IWAKI YUICHI Director / Officer M-Exempt A Common Stock 86,250 2.46 212.2K 927,350
2021-02-02 OBrien Geoffrey Officer A-Award A Employee Stock Option (Right to Buy) 99,000 6.89 682.1K 99,000
2021-02-02 Matsuda Kazuko Director / Officer A-Award A Employee Stock Option (Right to Buy) 325,000 6.89 2.24M 325,000
2021-02-02 IWAKI YUICHI Director / Officer A-Award A Employee Stock Option (Right to Buy) 495,000 6.89 3.41M 495,000
2021-01-11 3D Investment Partners Pte. Ltd. 10% Owner I Common Stock 0 0.00 5,502,047
2020-10-20 BEAVER CAROLYN Director A-Award A Stock Option (Right to Buy) 15,000 5.40 81.0K 15,000
2020-09-15 Nagao Hideki Director S-Sale D Common Stock 1,000 5.78 5.8K 15,000
2020-08-06 Nagao Hideki Director M-Exempt A Common Stock 15,000 2.58 38.7K 16,000
2020-06-19 Stepanow Edward C Jr. Officer 0 0.00 0
2020-06-16 Nagao Hideki Director A-Award A Stock Option (Right to Buy) 20,000 5.70 114.0K 20,000
2020-06-16 Kobayashi Yutaka Director A-Award A Stock Option (Right to Buy) 20,000 5.70 114.0K 20,000
2020-06-12 Matsuda Kazuko Director / Officer M-Exempt D Employee Stock Option (Right to Buy) 20,000 5.13 102.6K 0
2020-04-08 Matsuda Kazuko Director / Officer M-Exempt A Common Stock 28,446 2.54 72.3K 140,192
2020-04-08 IWAKI YUICHI Director / Officer M-Exempt A Common Stock 60,417 2.54 153.5K 841,100
2020-03-13 Matsuda Kazuko Director / Officer P-Purchase A Common Stock 2,000 3.62 7.2K 111,746
2020-03-12 IWAKI YUICHI Director / Officer P-Purchase A Common Stock 20,000 3.10 62.0K 780,683
2020-01-09 OBrien Geoffrey Officer A-Award A Employee Stock Option (Right to Buy) 165,000 9.67 1.60M 165,000
2020-01-09 Matsuda Kazuko Director / Officer A-Award A Employee Stock Option (Right to Buy) 243,750 9.67 2.36M 243,750
2020-01-09 IWAKI YUICHI Director / Officer A-Award A Employee Stock Option (Right to Buy) 412,500 9.67 3.99M 412,500
2019-06-12 Matsuda Kazuko Officer M-Exempt A Common Stock 37,000 4.80 177.6K 109,457
2019-06-10 Nagao Hideki Director A-Award A Stock Option (Right to Buy) 20,000 9.58 191.6K 20,000
2019-06-10 Kobayashi Yutaka Director A-Award A Stock Option (Right to Buy) 20,000 9.58 191.6K 20,000
2019-06-10 Ishizaka Yoshio Director A-Award A Stock Option (Right to Buy) 20,000 9.58 191.6K 20,000
2019-05-13 Nagao Hideki Director M-Exempt D Employee Stock Option (Right to Buy) 1,000 2.77 2.8K 0
2019-02-28 Okajima Masatsune Officer M-Exempt D Employee Stock Option (Right to Buy) 35,700 7.34 262.0K 0
2019-01-15 Okajima Masatsune Officer A-Award A Employee Stock Option (Right to Buy) 105,000 7.00 735.0K 105,000
2019-01-15 OBrien Geoffrey Officer A-Award A Employee Stock Option (Right to Buy) 205,000 7.00 1.44M 205,000
2019-01-15 Matsuda Kazuko Officer A-Award A Employee Stock Option (Right to Buy) 295,000 7.00 2.07M 295,000
2019-01-15 IWAKI YUICHI Director / Officer A-Award A Employee Stock Option (Right to Buy) 470,000 7.00 3.29M 470,000
2019-01-09 Okajima Masatsune Officer M-Exempt A Common Stock 41,250 2.20 90.8K 153,580
2019-01-03 IWAKI YUICHI Director / Officer M-Exempt A Common Stock 18,572 2.20 40.9K 759,392
2018-06-07 Nagao Hideki Director A-Award A Stock Option (Right to Buy) 20,000 9.34 186.8K 20,000
2018-06-07 Kobayashi Yutaka Director A-Award A Stock Option (Right to Buy) 20,000 9.34 186.8K 20,000
2018-06-07 Ishizaka Yoshio Director A-Award A Stock Option (Right to Buy) 20,000 9.34 186.8K 20,000
2018-06-01 Reyes Carla Officer 0 0.00 0
2018-03-05 IWAKI YUICHI Director / Officer M-Exempt A Common Stock 50,003 2.20 110.0K 740,594
2018-01-06 Okajima Masatsune Officer A-Award A Employee Stock Option (Right to Buy) 100,000 6.10 610.0K 100,000
2018-01-06 OBrien Geoffrey Officer A-Award A Employee Stock Option (Right to Buy) 200,000 6.10 1.22M 200,000
2018-01-06 Matsuda Kazuko Officer A-Award A Employee Stock Option (Right to Buy) 280,000 6.10 1.71M 280,000
2018-01-06 IWAKI YUICHI Director / Officer A-Award A Employee Stock Option (Right to Buy) 450,000 6.10 2.75M 450,000
2018-01-03 IWAKI YUICHI Director / Officer M-Exempt A Common Stock 53,363 4.42 235.9K 690,591
2017-12-12 Okajima Masatsune Officer M-Exempt A Common Stock 48,000 4.42 212.2K 108,941
2017-11-09 Nagao Hideki Director A-Award A Stock Option (Right to Buy) 20,000 6.51 130.2K 20,000
2017-11-02 IWAKI YUICHI Director / Officer M-Exempt A Common Stock 21,067 4.42 93.1K 637,228
2017-08-21 Ishizaka Yoshio Director P-Purchase A Common Stock 5,000 5.17 25.9K 10,000
2017-06-08 Kobayashi Yutaka Director A-Award A Stock Option (Right to Buy) 20,000 5.65 113.0K 20,000
2017-06-08 Ishizaka Yoshio Director A-Award A Stock Option (Right to Buy) 20,000 5.65 113.0K 20,000
2017-05-15 Kobayashi Yutaka Director P-Purchase A Common Stock 1,000 5.60 5.6K 25,000
2017-05-12 Kobayashi Yutaka Director P-Purchase A Common Stock 24,000 5.62 134.9K 24,000
2017-01-18 Okajima Masatsune Officer A-Award A Employee Stock Option (Right to Buy) 120,000 3.91 469.2K 120,000
2017-01-18 OBrien Geoffrey Officer A-Award A Employee Stock Option (Right to Buy) 115,000 3.91 449.7K 115,000
2017-01-18 Matsuda Kazuko Officer A-Award A Employee Stock Option (Right to Buy) 170,000 3.91 664.7K 170,000
2017-01-18 IWAKI YUICHI Director / Officer A-Award A Employee Stock Option (Right to Buy) 320,000 3.91 1.25M 320,000
2016-09-15 Kobayashi Yutaka Director P-Purchase A Common Stock 11,800 6.44 76.0K 81,800
2016-09-09 Kobayashi Yutaka Director P-Purchase A Common Stock 10,000 6.67 66.7K 70,000
2016-07-05 OBrien Geoffrey Officer M-Exempt A Common Stock 3,300 4.80 15.8K 8,300
2016-06-09 Kobayashi Yutaka Director A-Award A Stock Option (Right to Buy) 20,000 6.64 132.8K 20,000
2016-06-09 Ishizaka Yoshio Director A-Award A Stock Option (Right to Buy) 20,000 6.64 132.8K 20,000
2016-03-31 Selhorn Ryan J Officer 0 0.00 0
2016-03-14 Okajima Masatsune Officer X-InTheMoney A Common Stock 8,400 3.56 29.9K 51,138
2016-03-14 Matsuda Kazuko Officer X-InTheMoney A Common Stock 800 3.56 2.8K 62,003
2016-01-20 Okajima Masatsune Officer P-Purchase A Warrants (Right to Buy) 8,400 3.56 29.9K 8,400
2016-01-20 Matsuda Kazuko Officer S-Sale D Warrants (Right to Buy) 8,400 3.56 29.9K 800
2016-01-07 Okajima Masatsune Officer A-Award A Employee Stock Option (Right to Buy) 105,000 3.09 324.5K 105,000
2016-01-07 OBrien Geoffrey Officer A-Award A Employee Stock Option (Right to Buy) 105,000 3.09 324.5K 105,000
2016-01-07 Matsuda Kazuko Officer A-Award A Employee Stock Option (Right to Buy) 125,000 3.09 386.3K 125,000
2016-01-07 IWAKI YUICHI Director / Officer A-Award A Employee Stock Option (Right to Buy) 120,000 3.89 466.8K 120,000
2015-07-09 Kobayashi Yutaka Director A-Award A Stock Option (Right to Buy) 20,000 3.96 79.2K 20,000
2015-07-09 Ishizaka Yoshio Director A-Award A Stock Option (Right to Buy) 20,000 3.96 79.2K 20,000
2014-12-10 Kobayashi Yutaka Director P-Purchase A Common Stock 12,000 3.54 42.5K 60,000
2014-12-04 Okajima Masatsune Officer A-Award A Employee Stock option (right to buy) 15,000 3.24 48.6K 15,000
2014-12-04 OBrien Geoffrey Officer A-Award A Employee Stock option (right to buy) 15,000 3.24 48.6K 15,000
2014-12-04 Matsuda Kazuko Officer A-Award A Employee Stock option (right to buy) 105,000 2.64 277.2K 105,000
2014-12-04 IWAKI YUICHI Director / Officer A-Award A Employee Stock option (right to buy) 200,000 2.64 528.0K 200,000
2014-11-26 Kobayashi Yutaka Director P-Purchase A Common Stock 10,000 3.07 30.7K 48,000
2014-11-20 Kobayashi Yutaka Director P-Purchase A Common Stock 13,000 3.19 41.5K 38,000
2014-11-19 Ishizaka Yoshio Director P-Purchase A Common Stock 5,000 2.86 14.3K 5,000
2014-09-11 Kobayashi Yutaka Director P-Purchase A Common Stock 10,000 2.95 29.5K 25,000
2014-09-03 Kobayashi Yutaka Director P-Purchase A Common Stock 9,900 2.67 26.4K 15,000
2014-08-07 van den Boom Esther Officer A-Award A Stock Option (Right to Buy) 10,000 2.00 20.0K 10,000
2014-04-08 van den Boom Esther Officer 0 0.00 0
2014-04-08 Ishizaka Yoshio Director A-Award A Stock Option (Right to Buy) 15,000 2.05 30.8K 15,000
2013-12-12 Izumi Tatsuo Director S-Sale D Common Stock 70,300 2.10 147.8K 600,970
2013-12-02 Okajima Masatsune Officer A-Award A Employee Stock Option (right to buy) 80,000 4.10 328.0K 80,000
2013-12-02 OBrien Geoffrey Officer A-Award A Employee Stock Option (right to buy) 55,000 4.10 225.5K 55,000
2013-12-02 Matsuda Kazuko Officer A-Award A Employee Stock Option (right to buy) 80,000 4.10 328.0K 80,000
2013-12-02 IWAKI YUICHI Director / Officer A-Award A Employee Stock Option (right to buy) 145,000 4.10 594.5K 145,000
2013-11-18 Izumi Tatsuo Director P-Purchase A Common Stock 300 2.23 668.70 670,300
2013-10-15 OBrien Geoffrey Officer D Employee Stock Option (right to buy) 25,000 4.80 120.0K 0
2013-10-15 Nagao Hideki Director D Stock Option (right to buy) 15,000 2.58 38.7K 0
2013-10-15 Kobayashi Yutaka Director A-Award A Stock Option (right to buy) 15,000 2.58 38.7K 15,000
2013-05-21 Morris Arlene Director M-Exempt D Stock Option (Right to Buy) 7,800 2.40 18.7K 36,200
2013-05-13 Satomi Hajime 10% Owner I Common Stock 0 0.00 1,000,000
2013-05-13 Okajima Masatsune Officer A-Award A Stock Option (Right to Buy) 42,500 4.10 174.3K 42,500
2013-05-13 Matsuda Kazuko Officer A-Award A Stock Option (Right to Buy) 42,500 4.10 174.3K 42,500
2013-05-13 Johnson Kirk William Officer A-Award A Stock Option (Right to Buy) 42,500 4.10 174.3K 42,500
2013-05-13 Izumi Tatsuo Director P-Purchase A Warrant to Purchase Common Stock 119,047 3.15 375.0K 119,047
2013-05-13 IWAKI YUICHI Officer A-Award A Stock Option (Right to Buy) 62,500 4.10 256.3K 62,500
2013-05-13 COFFEE MICHAEL DENIS Officer A-Award A Stock Option (Right to Buy) 42,500 4.10 174.3K 42,500
2012-06-14 Okajima Masatsune Officer A-Award A Stock Option (Right to Buy) 63,750 2.46 156.8K 63,750
2012-06-14 OBrien Geoffrey Officer D Employee Stock Option (right to buy) 26,250 2.46 64.6K 0
2012-06-14 Matsuda Kazuko Officer A-Award A Stock Option (Right to Buy) 56,250 2.46 138.4K 56,250
2012-06-14 Johnson Kirk William Officer A-Award A Stock Option (Right to Buy) 63,750 2.46 156.8K 63,750
2012-06-14 IWAKI YUICHI Officer A-Award A Stock Option (Right to Buy) 86,250 2.46 212.2K 86,250
2012-06-14 COFFEE MICHAEL DENIS Officer A-Award A Stock Option (Right to Buy) 63,750 2.46 156.8K 63,750
2012-05-31 Izumi Tatsuo Director P-Purchase A Common Stock 5,200 1.81 9.4K 56,800
2012-05-29 O'Toole David D Director P-Purchase A Common Stock 5,000 1.78 8.9K 5,000
2012-05-29 Izumi Tatsuo Director P-Purchase A Common Stock 6,600 1.98 13.1K 51,600
2012-05-28 Izumi Tatsuo Director P-Purchase A Common Stock 30,000 1.94 58.2K 45,000
2012-05-10 Shigeta Hiroaki Director M-Exempt D Stock Option (Right to Buy) 1,000 2.28 2.3K 0
2012-04-10 O'Toole David D Director A-Award A Stock Option (Right to Buy) 15,000 2.59 38.9K 15,000
2012-04-04 Izumi Tatsuo Director M-Exempt A Common Stock 15,000 1.99 29.9K 15,000
2011-11-29 Nakata Kousuke Director I Common Stock, $0.001 par value 0 0.00 800,000
2011-10-13 Kissei Pharmaceutical Co., Ltd. 10% Owner D Common Stock ($0.001 par value) 0 0.00 800,000
2011-09-25 Izumi Tatsuo Director D Common Stock 0 0.00 613,200
2011-09-01 Matsuda Kazuko Officer D Options to Purchase Common Stock (Right to Buy) 20,000 5.13 102.6K 0
2011-09-01 Gennaro Michael J Officer 0 0.00 0
2011-07-18 Shigeta Hiroaki Director A-Award A Stock Option (Right to Buy) 14,000 2.40 33.6K 14,000
2011-07-18 PRENDERGAST JOHN K A Director A-Award A Stock Option (Right to Buy) 14,000 2.40 33.6K 14,000
2011-07-18 Morris Arlene Director A-Award A Stock Option (Right to Buy) 30,000 2.40 72.0K 30,000
2011-07-13 IWAKI YUICHI Director / Officer A-Award A Employee Stock option (Right to Buy) 100,000 2.54 254.0K 100,000
2011-06-14 Shigeta Hiroaki Director A-Award A Stock Option (Right to Buy) 1,000 2.28 2.3K 1,000
2011-06-14 PRENDERGAST JOHN K A Director A-Award A Stock Option (Right to Buy) 1,000 2.28 2.3K 1,000
2011-06-14 Morris Arlene Director A-Award A Stock Option (Right to Buy) 1,000 2.28 2.3K 1,000
2011-06-14 Himawan Jeff Director A-Award A Stock Option (Right to Buy) 1,000 2.28 2.3K 1,000
2011-03-29 OBrien Geoffrey Officer D Warrant (right to buy) 5,000 3.56 17.8K 0
2011-03-29 Matsuda Kazuko Officer D Common Stock Warrant (Right to Buy) 9,200 3.56 32.8K 0
2011-03-29 Johnson Kirk William Officer P-Purchase A Common Stock Warrants (Right to Buy) 2,200 3.56 7.8K 2,200
2011-03-29 IWAKI YUICHI Director / Officer P-Purchase A Common Stock Warrants (Right to Buy) 50,000 3.56 178.0K 50,000
2011-03-29 COFFEE MICHAEL DENIS Officer P-Purchase A Common Stock Warrants (Right to Buy) 4,000 3.56 14.2K 4,000
2010-06-14 COFFEE MICHAEL DENIS Officer A-Award A Stock Option (right to buy) 100,000 5.13 513.0K 100,000
2010-06-11 Shigeta Hiroaki Director A-Award A Stock Option (right to buy) 1,000 5.13 5.1K 1,000
2010-06-11 PRENDERGAST JOHN K A Director A-Award A Stock Option (right to buy) 1,000 5.13 5.1K 1,000
2010-06-11 Morris Arlene Director A-Award A Stock Option (right to buy) 1,000 5.13 5.1K 1,000
2010-06-11 Himawan Jeff Director A-Award A Stock Option (right to buy) 1,000 5.13 5.1K 1,000
2010-06-11 DUNTON ALAN W Director A-Award A Stock Option (right to buy) 1,000 5.13 5.1K 1,000
2010-02-01 Johnson Kirk William Officer A-Award A Stock Option (right to buy) 100,000 7.34 734.0K 100,000
2010-01-29 Okajima Masatsune Officer A-Award A Stock Option (right to buy) 35,700 7.34 262.0K 35,700
2010-01-29 IWAKI YUICHI Director / Officer A-Award A Stock Option (right to buy) 58,600 7.34 430.1K 58,600
2010-01-29 Asako Shintaro Officer A-Award A Stock Option (right to buy) 35,700 7.34 262.0K 35,700
2009-12-18 BVF PARTNERS L P/IL 10% Owner I Secured Convertible Note 821,233 6.80 5.58M 0
2009-12-12 Nagao Hideki Director D Stock Option (right to buy) 1,000 2.77 2.8K 0
2009-09-14 Shigeta Hiroaki Director A-Award A Stock Option (right to buy) 1,000 6.18 6.2K 1,000
2009-07-28 Kalafer Michael E Officer P-Purchase A Common Stock 19,586 4.42 86.6K 31,744
2009-06-12 PRENDERGAST JOHN K A Director A-Award A Stock Option (right to buy) 1,000 2.77 2.8K 1,000
2009-06-12 Nagao Hideki Director A-Award A Stock Option (right to buy) 1,000 2.77 2.8K 1,000
2009-06-12 Morris Arlene Director A-Award A Stock Option (right to buy) 1,000 2.77 2.8K 1,000
2009-06-12 Himawan Jeff Director A-Award A Stock Option (right to buy) 1,000 2.77 2.8K 1,000
2009-06-12 DUNTON ALAN W Director A-Award A Stock Option (right to buy) 1,000 2.77 2.8K 1,000
2009-02-02 IWAKI YUICHI Director / Officer P-Purchase A Common Stock, par value $0.001 1,800 2.25 4.1K 643,972
2009-01-30 Okajima Masatsune Officer A-Award A Stock Option (right to buy) 41,250 2.20 90.8K 41,250
2009-01-30 Kalafer Michael E Officer A-Award A Stock Option (right to buy) 41,250 2.20 90.8K 41,250
2009-01-30 IWAKI YUICHI Director / Officer A-Award A Stock Option (right to buy) 97,500 2.20 214.5K 97,500
2009-01-30 GAMMANS RICHARD E SR Officer A-Award A Stock Option (right to buy) 60,000 2.20 132.0K 60,000
2009-01-30 Asako Shintaro Officer A-Award A Stock Option (right to buy) 60,000 2.20 132.0K 60,000
2009-01-27 IWAKI YUICHI Director / Officer P-Purchase A Common Stock, par vlaue $0.001 1,200 2.19 2.6K 642,172
2009-01-26 IWAKI YUICHI Director / Officer P-Purchase A Common Stock, par value $0.001 1,650 2.15 3.5K 640,972

Executive team

Top executives
EBIT / Employee
-9.2K
Shares Outstanding
49.22M

Executive compensation

Executive compensation (annual)
# Year Executive Salary Bonus Stock award Option award Incentive Other Total % Stock-
based
Filing
1 2025 Yuichi Iwaki, M.D., Ph.D. President and Chief Executive Officer 657.4K 729.6K 328.7K 21.0K 1.74M 42.01%
2 2025 Kazuko Matsuda, M.D., Ph.D., MPH Senior Vice President, Chief Medical Officer 514.4K 589.9K 205.8K 21.0K 1.33M 44.32%
3 2025 David H. Crean, Ph.D. Chief Business Officer 120.0K 120.0K 0.00%
4 2024 Yuichi Iwaki, M.D., Ph.D. President and Chief Executive Officer 657.4K 401.5K 328.7K 20.7K 1.41M 28.51%
5 2024 Kazuko Matsuda, M.D., Ph.D., MPH Senior Vice President, Chief Medical Officer 505.4K 301.1K 176.9K 20.7K 1.00M 29.99%
6 2024 Kazuko Matsuda, M.D., Ph.D., MPH Chief Medical Officer 505.4K 301.1K 176.9K 20.7K 1.00M 29.99%
7 2024 Geoffrey O’Brien, J.D./M.B.A. Former Vice President 155.8K 14.9K 170.7K 0.00%
8 2024 David H. Crean, Ph.D. Chief Business Officer 99.0K 99.0K 0.00%
9 2023 Yuichi Iwaki, M.D., Ph.D. President and Chief Executive Officer 657.4K 481.1K 230.1K 19.8K 1.39M 34.65%
10 2023 Kazuko Matsuda, M.D., Ph.D. Chief Medical Officer 505.4K 360.8K 123.8K 19.8K 1.01M 35.73%
11 2023 Kazuko Matsuda, M.D., Ph.D., MPH Chief Medical Officer 505.4K 360.8K 123.8K 19.8K 1.01M 35.73%
12 2023 Geoffrey O’Brien, J.D./M.B.A. Former Vice President 378.6K 192.4K 92.7K 19.8K 683.5K 28.15%
13 2023 Geoffrey O’Brien, J.D./M.B.A. Vice President 378.6K 192.4K 92.7K 19.8K 683.5K 28.15%
14 2022 Yuichi Iwaki, M.D., Ph.D. President and Chief Executive Officer 620.2K 359.6K 294.6K 18.3K 1.29M 27.82%
15 2022 Kazuko Matsuda, M.D., Ph.D. Chief Medical Officer 476.8K 228.8K 158.5K 18.3K 882.5K 25.93%
16 2022 Geoffrey O’Brien, J.D./M.B.A. Vice President 357.2K 117.7K 118.8K 18.3K 611.9K 19.23%
17 2021 Yuichi Iwaki, M.D., Ph.D. President and Chief Executive Officer 596.3K 1.98M 164.0K 17.4K 2.76M 71.80%
18 2021 Kazuko Matsuda, M.D., Ph.D. Chief Medical Officer 458.5K 1.26M 88.3K 17.4K 1.82M 69.08%
19 2021 Geoffrey O’Brien, J.D./M.B.A. Vice President 343.4K 648.1K 66.1K 17.4K 1.08M 60.29%
20 2020 Yuichi Iwaki, M.D., Ph.D. President and Chief Executive Officer 586.9K 2.10M 264.1K 17.1K 2.97M 70.73%
21 2020 Kazuko Matsuda, M.D., Ph.D. Chief Medical Officer 451.3K 1.24M 157.9K 17.1K 1.87M 66.44%
22 2020 Geoffrey O’Brien, J.D./M.B.A. Vice President 338.0K 839.2K 53.2K 17.1K 1.25M 67.27%
23 2019 Yuichi Iwaki, M.D., Ph.D. President and Chief and Executive Officer 572.1K 2.96M 214.5K 16.8K 3.76M 78.64%
24 2019 Yuichi Iwaki, M.D., Ph.D. President and Chief Executive Officer 572.1K 2.96M 214.5K 16.8K 3.76M 78.64%
25 2019 Kazuko Matsuda, M.D., Ph.D. Chief Medical Officer 439.8K 1.75M 131.9K 16.8K 2.34M 74.81%
26 2019 Geoffrey O’Brien, J.D./M.B.A. Vice President 329.4K 1.18M 98.8K 16.8K 1.63M 72.67%
27 2018 Yuichi Iwaki, M.D., Ph.D. President and Chief Executive Officer 551.1K 1.91M 372.0K 16.5K 2.85M 67.07%
28 2018 Yuichi Iwaki, M.D., Ph.D. President and Chief and Executive Officer 551.1K 1.91M 372.0K 16.5K 2.85M 67.07%
29 2018 Kazuko Matsuda, M.D., Ph.D. Chief Medical Officer 394.8K 1.20M 213.2K 16.5K 1.83M 65.79%
30 2018 Geoffrey O’Brien, J.D./M.B.A. Vice President 307.7K 834.7K 166.2K 16.5K 1.33M 62.99%
31 2017 Yuichi Iwaki, M.D., Ph.D. President and Chief and Executive Officer 533.5K 1.74M 266.8K 16.2K 1.94M 89.91%
32 2017 Kazuko Matsuda, M.D., Ph.D. Chief Medical Officer 382.2K 1.08M 172.0K 8.3K 1.65M 65.82%
33 2017 Geoffrey O’Brien, J.D./M.B.A. Vice President 297.9K 773.7K 128.1K 16.2K 1.22M 63.63%
34 2017 Masatsune Okajima Vice President and Head of Japanese Office 310.3K 386.9K 77.6K 14.7K 789.4K 49.01%
35 2017 Ryan Selhorn, CPA Chief Financial Officer 132.3K 132.3K 0.00%
36 2016 Yuichi Iwaki, M.D., Ph.D. President and Chief and Executive Officer 523.0K 1.14M 261.5K 15.9K 1.94M 58.66%
37 2016 Kazuko Matsuda, M.D., Ph.D. Chief Medical Officer 347.5K 697.8K 121.6K 8.5K 1.18M 59.37%
38 2016 Masatsune Okajima Vice President and Head of Japanese Office 304.2K 386.9K 106.5K 18.4K 815.9K 47.42%
39 2016 Geoffrey O’Brien, J.D./M.B.A. Vice President 259.1K 374.0K 90.7K 15.9K 739.6K 50.57%
40 2016 Ryan Selhorn, CPA Chief Financial Officer 58.8K 58.8K 0.00%
41 2016 Esther van den Boom, CPA Former Chief Financial Officer 37.0K 37.0K 0.00%
42 2015 Yuichi Iwaki, M.D., Ph.D. President and Chief and Executive Officer 518.9K 510.9K 259.4K 15.9K 1.31M 39.14%
43 2015 Kazuko Matsuda, M.D., Ph.D. Chief Medical Officer 344.7K 255.4K 120.6K 9.1K 729.9K 35.00%
44 2015 Masatsune Okajima Vice President and Head of Japanese Office 301.8K 214.6K 105.6K 15.9K 637.8K 33.64%
45 2015 Geoffrey O’Brien, J.D./M.B.A. Vice President 257.0K 214.6K 90.0K 15.9K 577.4K 37.16%
46 2015 Esther van den Boom, CPA Former Chief Financial Officer 95.1K 95.1K 0.00%
47 2014 Yuichi Iwaki, M.D., Ph.D. President and Chief and Executive Officer 504.8K 252.4K 12.0K 769.1K 0.00%
48 2014 Yuichi Iwaki, M.D., Ph.D. President and Chief and Executive Officer 504.8K 252.4K 12.0K 769.1K 0.00%
49 2014 Kazuko Matsuda, M.D., Ph.D. Chief Medical Officer 293.6K 102.7K 15.6K 682.8K 0.00%
50 2014 Kazuko Matsuda, M.D., Ph.D. Chief Medical Officer 293.6K 270.9K 102.7K 15.6K 682.8K 39.68%
51 2014 Masatsune Okajima Vice President and Head of Japanese Office 293.6K 102.7K 17.5K 447.7K 0.00%
52 2014 Masatsune Okajima Vice President and Head of Japanese Office 293.6K 33.9K 102.7K 17.5K 447.7K 7.56%
53 2013 Yuichi Iwaki, M.D., Ph.D. President and Chief and Executive Officer 504.8K 957.1K 138.8K 14.7K 1.62M 59.25%
54 2013 Yuichi Iwaki, M.D., Ph.D. President and Chief and Executive Officer 504.8K 138.8K 14.7K 1.62M 0.00%
55 2013 Kazuko Matsuda, M.D., Ph.D. Chief Medical Officer 293.6K 56.5K 23.8K 915.0K 0.00%
56 2013 Kazuko Matsuda, M.D., Ph.D. Chief Medical Officer 293.6K 541.2K 56.5K 23.8K 915.0K 59.14%
57 2013 Masatsune Okajima Vice President and Head of Japanese Office 293.6K 541.2K 56.5K 18.4K 909.6K 59.49%
58 2013 Masatsune Okajima Vice President and Head of Japanese Office 293.6K 56.5K 18.4K 909.6K 0.00%
59 2012 Yuichi Iwaki, M.D., Ph.D. President and Chief and Executive Officer 504.8K 189.3K 14.7K 907.4K 0.00%
60 2012 Michael Coffee Chief Business Officer 309.0K 132.5K 81.1K 76.1K 598.7K 22.13%
61 2012 Michael Gennaro Chief Financial Officer 594.9K 594.9K 0.00%
62 2012 Kirk Johnson, Ph.D. Chief Scientific Officer 293.6K 132.5K 77.1K 61.0K 564.0K 23.48%
63 2012 Masatsune Okajima Vice President and Head of Japanese Office 293.6K 77.1K 21.4K 524.4K 0.00%
64 2012 Kazuko Matsuda, M.D., Ph.D. Chief Medical Officer 293.6K 67.4K 22.7K 516.1K 0.00%
65 2011 Yuichi Iwaki, M.D., Ph.D. President and Chief Executive Officer 490.1K 203.4K 14.7K 1.04M 0.00%
66 2011 Yuichi Iwaki, M.D., Ph.D. President and Chief and Executive Officer 490.1K 332.0K 80.9K 14.7K 917.6K 36.18%
67 2011 Kazuko Matsuda, M.D., Ph.D., MPH Chief Medical Officer 255.0K 85.9K 12.1K 666.7K 0.00%
68 2011 Michael Coffee Chief Business Officer 300.0K 262.0K 34.7K 67.5K 664.2K 39.45%
69 2011 Kirk Johnson, Ph.D. Chief Scientific Officer 285.0K 262.0K 32.9K 59.2K 639.1K 41.00%
70 2011 Kazuko Matsuda, M.D., Ph.D. Chief Medical Officer 255.0K 313.7K 36.0K 12.1K 606.8K 51.69%
71 2011 Masatsune Okajima Vice President and Head of Japanese Office 285.0K 262.0K 32.9K 17.8K 597.7K 43.84%
72 2011 Shintaro Asako, CPA Former Chief Financial Officer 23.8K 237.5K 261.3K 0.00%
73 2011 Michael Gennaro Chief Financial Officer 215.9K 215.9K 0.00%
74 2011 Michael Gennaro Chief Financial Officer 215.7K 215.7K 0.00%
75 2010 Kirk Johnson, Ph.D. Chief Scientific Officer 261.3K 68.6K 763.8K 0.00%
76 2010 Kirk Johnson, Ph.D. Chief Scientific Officer 261.3K 68.6K 763.8K 0.00%
77 2010 Yuichi Iwaki, M.D., Ph.D. . President and Chief Executive Officer 490.1K 14.7K 759.1K 0.00%
78 2010 Yuichi Iwaki, M.D., Ph.D. President and Chief Executive Officer 490.1K 14.7K 759.1K 0.00%
79 2010 Michael Coffee Chief Business Officer 164.3K 28.8K 494.5K 0.00%
80 2010 Michael Coffee Chief Business Officer 164.3K 28.8K 494.5K 0.00%
81 2010 Masatsune Okajima Vice President and Head of Japanese Office 285.0K 16.7K 456.6K 0.00%
82 2010 Shintaro Asako, CPA Former Chief Financial Officer 285.0K 14.7K 454.6K 0.00%
83 2009 Yuichi Iwaki, M.D., Ph.D. . President and Chief Executive Officer 473.5K 236.7K 14.7K 838.0K 0.00%
84 2009 Yuichi Iwaki, M.D., Ph.D. President and Chief Executive Officer 473.5K 236.7K 14.7K 838.0K 0.00%
85 2009 Richard Gammans, Ph.D. Former Chief Development Officer 177.1K 409.8K 656.5K 0.00%
86 2009 Shintaro Asako, CPA Former Chief Financial Officer 243.3K 100.0K 14.7K 427.6K 0.00%
87 2009 Shintaro Asako, CPA Chief Financial Officer 243.3K 100.0K 14.7K 427.6K 0.00%
88 2009 Masatsune Okajima Vice President and Head of Japanese Office 248.6K 100.0K 16.7K 413.1K 0.00%
89 2009 Michael Kalafer, M.D. Former Chief Medical Officer 121.7K 240.6K 410.1K 0.00%
90 2008 Yuichi Iwaki, M.D., Ph.D. . President and Chief Executive Officer 464.2K 139.3K 13.8K 926.7K 0.00%
91 2008 Yuichi Iwaki, M.D., Ph.D. President and Chief Executive Officer 464.2K 139.3K 13.8K 926.7K 0.00%
92 2008 Richard Gammans, Ph.D. Former Chief Development Officer 382.0K 80.8K 13.8K 705.1K 0.00%
93 2008 Richard Gammans, Ph.D. Chief Development Officer 382.0K 80.8K 13.8K 705.1K 0.00%
94 2008 Michael Kalafer, M.D. Former Chief Medical Officer 260.0K 51.8K 13.8K 494.1K 0.00%
95 2008 Michael Kalafer, M.D. Former Chief Medical Officer 260.0K 51.8K 13.8K 494.1K 0.00%
96 2008 Shintaro Asako, CPA Former Chief Financial Officer 236.2K 50.2K 13.8K 476.4K 0.00%
97 2008 Shintaro Asako, CPA Chief Financial Officer 236.2K 50.2K 13.8K 476.4K 0.00%
98 2008 Masatsune Okajima Vice President and Head of Japanese Office 241.3K 45.8K 17.0K 418.4K 0.00%
99 2007 Yuichi Iwaki, M.D., Ph.D. President and Chief Executive Officer 452.0K 90.4K 54.5K 596.9K 0.00%
100 2007 Yuichi Iwaki, M.D., Ph.D. . President and Chief Executive Officer 452.0K 90.4K 54.5K 596.9K 0.00%
101 2007 Richard Gammans, Ph.D. Chief Development Officer 297.0K 52.1K 113.4K 462.7K 0.00%
102 2007 Richard Gammans, Ph.D. Former Chief Development Officer 297.0K 52.1K 113.4K 462.7K 0.00%
103 2007 Richard Gammans, Ph.D. Chief Business Officer 297.0K 52.1K 113.6K 462.7K 0.00%
104 2007 Kenneth Locke, Ph.D. Chief Scientific Officer 260.0K 36.4K 36.7K 333.1K 0.00%
105 2007 Shintaro Asako, CPA Chief Financial Officer 230.0K 40.3K 32.9K 303.2K 0.00%
106 2007 Masatsune Okajima Vice President and Head of Japanese Office 235.0K 32.9K 19.7K 287.6K 0.00%
107 2006 Yuichi Iwaki, M.D., Ph.D. President and Chief Executive Officer 350.0K 150.0K 3.09M 0.00%
108 2006 Richard Gammans, Ph.D. Chief Business Officer 280.0K 84.0K 102.1K 1.83M 0.00%
109 2006 Richard Gammans, Ph.D. Chief Development Officer 280.0K 84.0K 102.1K 1.83M 0.00%
110 2006 Kenneth Locke, Ph.D. Chief Scientific Officer 245.0K 73.0K 31.4K 1.52M 0.00%
111 2006 Masatsune Okajima Vice President and Head of Japanese Office 73.3K 60.0K 5.0K 1.21M 0.00%
112 2006 Shintaro Asako, CPA Chief Financial Officer 173.3K 73.0K 31.8K 1.19M 0.00%
113 2005 Shintaro Asako, CPA Vice President, Accounting and Administration 68.6K 30.0K 15.3K 113.9K 0.00%
114 2004 Brian Anderson Chief Business Officer
115 2004 Richard E. Gammans, Ph.D. Chief Development Officer
116 2004 Mark Lotz Vice President, Regulatory Affairs
117 2004 Joji Suzuki, M.D., Ph.D. Vice President, Finance
CEO compensation breakdown

Proxy statements

Proxy statements (DEF 14A)
Filing date Form type Filing
2026-04-29 DEFA14A
2026-04-29 DEF 14A
2026-04-17 PRE 14A
2025-04-28 DEFA14A
2025-04-28 DEF 14A
2024-04-26 DEFA14A
2024-04-26 DEF 14A
2023-04-26 DEFA14A
2023-04-26 DEF 14A
2022-04-26 DEFA14A
2022-04-26 DEF 14A

Recent SEC filings

Recent SEC filings
Filing date Form type Filing
2026-04-29 DEFA14A
2026-04-29 DEF 14A
2026-04-29 ARS
2026-04-20 PRER14A
2026-04-17 PRE 14A
2026-03-10 10-K
2026-02-20 8-K
2026-01-20 4
2026-01-20 4
2025-12-30 8-K

Executive team

NameTitleCompensationGender
Yuichi Iwaki Co-Founder, President, Chief Executive Officer & Chairman 1M
Kazuko Matsuda Senior VP, Chief Medical Officer & Director 741.2K
David H. Crean Chief Business Officer 120.0K
Jason J. Kruger Chief Financial Officer & Principal Financial Officer male
ESG Rating
B
BIOTECHNOLOGY
Rank: 40 out of 710
2022
E (Environmental)
61.8 / 56.3
Company / Sector avg.
S (Social)
66.1 / 62.4
Company / Sector avg.
G (Governance)
66.9 / 60.9
Company / Sector avg.
ESG Total
64.9 / 59.9
Company / Sector avg.
ESG Score History BIOTECHNOLOGY
Benchmark vs Sector
Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend history

Earnings history

Earnings reports

Stock splits