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Metagenomi, Inc. Common Stock (MGX)

USD1.29 -0.03 (-2.27%)
US NASDAQ Healthcare Biotechnology
Address 5959 Horton Street 94608
Emeryville, US
CEO Jian Irish
IPO 2006-04-06
CIK 1785279 ISIN US59102M1045

Explore sections of this company profile

Description

Metagenomi, Inc. operates as a biotechnology company focused on gene editing, committed to developing therapeutic solutions for patients. The company utilizes a distinctive genome editing toolkit, sourced from metagenomics, for its development efforts within the United States. This advanced toolkit comprises programmable nucleases, base editors, and sophisticated RNA and DNA-mediated integration systems, notably prime editing and CRISPR-associated transposases. Metagenomi has established several key collaborations: a strategic alliance with ModernaTX, Inc. to explore new genome editing systems for in vivo human therapeutic applications; a development and licensing agreement with Affini-T Therapeutics, Inc. to create and commercialize gene-edited T-cell receptor therapies for human cancer; and a partnership with Ionis Pharmaceuticals, Inc. to research, develop, and market investigational medicines leveraging genome editing technologies. Founded in 2016, the company is based in Emeryville, California.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
USD1.29 -0.03 (-2.27%)
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Volume Profile
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Liquidity & share structure
Average Volume
166.7K
Beta
0.65
Float Shares
27.33M
Free Float %
72.6%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
-4.26% -3.57% -2.17% -6.90% -27.42% -16.67% -12.90% -86.91% -86.91% -86.91% -86.91%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
vs.
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Analyst Consensus (5 ratings, all time) Buy
Price Targets & DCF
Current price
1.29
Low 7.00 +442.6%
Consensus 14.50 +1,024.0%
Median 14.50 +1,024.0%
High 22.00 +1,605.4%
Ratings Trend (MoM) 80% Bullish
Rating 2026-05 Change
Strong Buy 0 0
Buy 4 0
Hold 1 0
Sell 0 0
Strong Sell 0 0
Price Target Summary
Period # Analysts Avg Target
Last Month
Last Quarter
Last Year
All Time 2
14.50
+1,024.0%
Quality scores
Altman Z-Score
-2.52
Distress
Piotroski F-Score
1 / 9
Weak
MOAT Score
0 / 10
No MOAT
Composite Rating
C
Overall Score
2 / 5
Medium
DCF Score
1 / 5
Low
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
2 / 5
Medium
P/E Score
1 / 5
Low
P/Book Score
5 / 5
High
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
    -51.8% Q1'26: -69.8% (vs Q1'25)
  • EPS growth Biotechnology: +29.7%
    -12.9% Q1'26: +10.3% (vs Q1'25)
  • FCF margin FCF growth · Biotechnology: +16.2%
    -449.5% Q1'26: -1,698.7% (vs Q1'25)
  • EBIT margin Biotechnology: +0.0%
    -380.9% Q1'26: +0.0% (vs Q1'25)
  • ROIC Biotechnology: -16.1%
    -249.7% Q1'26: +0.0% (vs Q1'25)
  • Share dilution Biotechnology: -3.4%
    -0.5% Q1'26: +1.5% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    -0.45× Q1'26: -0.40× (vs Q1'25)
Valuation Multiples From To
Price Forecast (3Y) From To
Model
Adjust
P/E
Theoretical Return — If Invested Today

* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.

DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (0.65) × ERP
WACC = 55% × Ke + 45% × Kd (4.1%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Current price: 1.29
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2023
actual
Dec 2024
actual
Dec 2025
actual
Dec 2026
4 Rev. Ana.
3 EPS Ana.
Dec 2027
4 Rev. Ana.
4 EPS Ana.
Dec 2028
2 Rev. Ana.
2 EPS Ana.
Dec 2029
1 Rev. Ana.
1 EPS Ana.
Dec 2030
1 Rev. Ana.
1 EPS Ana.
Revenue
44.76M
est: 47.26M (-5.3%)
52.30M
est: 51.81M (+0.9%)
25.21M
est: 28.63M (-11.9%)
14.81M
13.49M – 16.13M
-48.3% YoY
15.19M
14.92M – 15.45M
+2.5% YoY
20.00M
16.12M – 29.98M
+31.7% YoY
20.00M
16.12M – 29.98M
+0.0% YoY
20.00M
16.12M – 29.98M
+0.0% YoY
EBITDA
-74.29M
est: -47.26M (-57.2%)
-83.49M
est: -51.81M (-61.2%)
-90.70M
est: -28.63M (-216.8%)
-14.81M
-16.13M – -13.49M
+48.3% YoY
-15.19M
-15.45M – -14.92M
-2.5% YoY
-20.00M
-29.98M – -16.12M
-31.7% YoY
-20.00M
-29.98M – -16.12M
+0.0% YoY
-20.00M
-29.98M – -16.12M
+0.0% YoY
EBIT
-78.49M
est: -47.26M (-66.1%)
-88.90M
est: -51.81M (-71.6%)
-96.01M
est: -28.63M (-235.4%)
-14.81M
-16.13M – -13.49M
+48.3% YoY
-15.19M
-15.45M – -14.92M
-2.5% YoY
-20.00M
-29.98M – -16.12M
-31.7% YoY
-20.00M
-29.98M – -16.12M
+0.0% YoY
-20.00M
-29.98M – -16.12M
+0.0% YoY
Net Income
-68.26M
est: -440.12M (+84.5%)
-78.06M
est: -90.46M (+13.7%)
-87.87M
est: -87.87M (+0.0%)
-82.42M
-87.39M – -77.46M
+6.2% YoY
-60.41M
-83.67M – -37.14M
+26.7% YoY
-81.10M
-99.74M – -62.47M
-34.3% YoY
-72.64M
-119.78M – -54.33M
+10.4% YoY
-67.05M
-110.56M – -50.15M
+7.7% YoY
SGA
28.85M
est: 409.95M (-93.0%)
32.02M
est: 449.43M (-92.9%)
26.79M
est: 248.33M (-89.2%)
128.48M
117.03M – 139.93M
-48.3% YoY
131.73M
129.42M – 134.05M
+2.5% YoY
173.50M
139.86M – 260.10M
+31.7% YoY
173.50M
139.86M – 260.10M
+0.0% YoY
173.50M
139.86M – 260.10M
+0.0% YoY
EPS
-1.82
est: -9.86 (+81.5%)
-2.09
est: -2.48 (+15.7%)
-2.36
est: -2.36 (0.0%)
-2.20
-2.35 – -2.08
+6.9% YoY
-1.68
-2.25 – -1.00
+23.7% YoY
-2.18
-2.68 – -1.68
-29.9% YoY
-1.95
-3.22 – -1.46
+10.4% YoY
-1.80
-2.97 – -1.35
+7.7% YoY
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-11 C 2/5 1/5 1/5 1/5 2/5 1/5 5/5
2026-05-08 C 2/5 1/5 1/5 1/5 2/5 1/5 5/5
2026-05-07 C 2/5 1/5 1/5 1/5 2/5 1/5 5/5
2026-05-06 C 2/5 1/5 1/5 1/5 2/5 1/5 5/5
2026-05-05 C 2/5 1/5 1/5 1/5 2/5 1/5 5/5
2026-05-04 C 2/5 1/5 1/5 1/5 2/5 1/5 5/5
2026-05-01 C 2/5 1/5 1/5 1/5 2/5 1/5 5/5
2026-04-30 C 2/5 1/5 1/5 1/5 2/5 1/5 5/5
2026-04-29 C 2/5 1/5 1/5 1/5 2/5 1/5 5/5
2026-04-28 C 2/5 1/5 1/5 1/5 2/5 1/5 5/5
2026-04-27 C 2/5 1/5 1/5 1/5 2/5 1/5 5/5
2026-04-24 C 2/5 1/5 1/5 1/5 2/5 1/5 5/5
2026-04-23 C 2/5 1/5 1/5 1/5 1/5 1/5 5/5
2026-04-22 C 2/5 1/5 1/5 1/5 1/5 1/5 5/5
2026-04-21 C 2/5 1/5 1/5 1/5 1/5 1/5 5/5
2026-04-20 C 2/5 1/5 1/5 1/5 1/5 1/5 5/5
2026-04-17 C 2/5 1/5 1/5 1/5 1/5 1/5 5/5
2026-04-16 C 2/5 1/5 1/5 1/5 1/5 1/5 5/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
-124.46M
OE per share TTM
-3.32
Owner's Yield
-245.31%
Maintenance CapEx ratio
Maint CapEx / Avg PPE
161.0%

Ownership Overview

Ownership breakdown
At a glance
Institutional holders
13
Total invested
2.61M
Insider transactions (90d)
0
Beneficial owners (>5%)
5
Beneficial owners (>5%)
# Reporting person Amount owned % of class Sole voting Shared voting Sole dispositive Shared dispositive Type Citizenship Filing date SEC filing
1 Bayer Aktiengesellschaft 4.05M 10.80% 4.05M HC, CO Citizenship or Place of Organization 2024-11-06
2 Bayer HealthCare LLC 4.05M 10.80% 4.05M CO Citizenship or Place of Organization 2024-11-06
3 Bayer US Holding LP 4.05M 10.80% 4.05M PN Citizenship or Place of Organization 2024-11-06
4 Bayer World Investments B.V. 4.05M 10.80% 4.05M CO Citizenship or Place of Organization 2024-11-06
5 S 600.5K 1.60% 600.5K 600.5K 600.5K 600.5K PN Cayman Islands 2024-05-10

Institutional Activity (13F)

Institutional ownership trend From To
13F snapshot — 2026 Q1
Investors holding
13
-41 vs prev Q
New positions
3
Closed positions
44
Increased
5
Reduced
4
Put/Call ratio
0.00
Calls held
Puts held
Top institutional holders
# Investor Shares / Δ Mkt value / Δ Own% / Δ Weight% / Δ Avg px / Perf. Hold / Status
1 12.5K +12.5K (+100.0%) 20.25M +20.3M (+100.0%) 0.03% +0.034 pp 0.01% +0.006 pp USD1.62 +0.0% 1 qtrs NEW
2 VANGUARD GROUP INC 1.27M +28.7K (+2.3%) 2.06M -884.6K (-30.1%) 3.40% +0.060 pp 0.00% +0.000 pp USD4.02 -59.7% 8 qtrs
3 RENAISSANCE TECHNOLOGIES LLC 628.4K +461.4K (+276.3%) 1.02M +622.2K (+157.2%) 1.68% +1.233 pp 0.00% +0.001 pp USD1.76 -8.0% 6 qtrs
4 CATALIO CAPITAL MANAGEMENT, LP 529.0K +— (+0.0%) 857.0K -396.7K (-31.6%) 1.42% -0.007 pp 0.15% -0.080 pp USD3.61 -55.1% 5 qtrs
5 PEAPOD LANE CAPITAL LLC 497.7K -16.2K (-3.1%) 806.2K -412.2K (-33.8%) 1.33% -0.050 pp 0.69% -0.404 pp USD2.95 -45.1% 5 qtrs
6 TWO SIGMA INVESTMENTS, LP 441.4K +233.9K (+112.7%) 715.0K +223.2K (+45.4%) 1.18% +0.623 pp 0.00% +0.000 pp USD1.99 -18.6% 8 qtrs
7 JANE STREET GROUP, LLC 433.9K +335.6K (+341.6%) 702.9K +470.0K (+201.8%) 1.16% +0.897 pp 0.00% +0.000 pp USD1.59 +1.9% 5 qtrs
8 BRIDGEWAY CAPITAL MANAGEMENT, LLC 395.8K +200.0K (+102.1%) 641.2K +177.2K (+38.2%) 1.06% +0.533 pp 0.01% +0.004 pp USD1.93 -16.1% 6 qtrs
9 GEODE CAPITAL MANAGEMENT, LLC 305.9K +14.0K (+4.8%) 495.8K -196.3K (-28.4%) 0.82% +0.034 pp 0.00% +0.000 pp USD4.08 -60.3% 8 qtrs
10 PURA VIDA INVESTMENTS, LLC 264.4K +— (+0.0%) 428.3K -198.3K (-31.6%) 0.71% -0.004 pp 1.60% -2.217 pp USD4.07 -60.2% 8 qtrs
11 MILLENNIUM MANAGEMENT LLC 235.2K -75.5K (-24.3%) 381.0K -355.3K (-48.3%) 0.63% -0.207 pp 0.00% 0.000 pp USD1.70 -4.7% 8 qtrs
12 BLACKROCK, INC. 224.1K +690.0 (+0.3%) 363.1K -166.5K (-31.4%) 0.60% -0.001 pp 0.00% +0.000 pp USD3.05 -46.9% 6 qtrs
13 TWO SIGMA ADVISERS, LP 201.3K +150.9K (+299.4%) 326.1K +206.7K (+173.0%) 0.54% +0.403 pp 0.00% +0.000 pp USD1.81 -10.5% 2 qtrs
14 CITADEL ADVISORS LLC 178.2K +178.2K (+100.0%) 288.6K +288.6K (+100.0%) 0.48% +0.477 pp 0.00% +0.000 pp USD1.62 +0.0% 8 qtrs
15 STATE STREET CORP 120.4K -1.1K (-0.9%) 195.1K -93.0K (-32.3%) 0.32% -0.005 pp 0.00% +0.000 pp USD3.11 -47.9% 7 qtrs
16 WELLS FARGO & COMPANY/MN 118.4K +16.4K (+16.1%) 191.8K -49.9K (-20.7%) 0.32% +0.043 pp 0.00% +0.000 pp USD4.03 -59.8% 8 qtrs
17 RESOLUTE ADVISORS LLC 89.9K +— (+0.0%) 145.7K -67.5K (-31.6%) 0.24% -0.001 pp 0.05% -0.007 pp USD4.56 -64.5% 8 qtrs
18 MARSHALL WACE, LLP 79.1K -12.2K (-13.3%) 128.2K -88.2K (-40.8%) 0.21% -0.034 pp 0.00% 0.000 pp USD1.48 +9.5% 8 qtrs
19 NORTHERN TRUST CORP 75.2K +35.2K (+88.1%) 121.8K +27.0K (+28.5%) 0.20% +0.094 pp 0.00% +0.000 pp USD2.68 -39.6% 8 qtrs
20 XTX TOPCO LTD 69.0K +53.8K (+353.4%) 111.8K +75.7K (+209.9%) 0.18% +0.144 pp 0.00% +0.001 pp USD1.79 -9.5% 2 qtrs
21 ACADIAN ASSET MANAGEMENT LLC 64.9K +64.9K (+100.0%) 105.0K +105.0K (+100.0%) 0.17% +0.174 pp 0.00% +0.000 pp USD1.62 +0.0% 1 qtrs NEW
22 RBF CAPITAL, LLC 64.0K -6.8K (-9.5%) 103.7K -64.0K (-38.2%) 0.17% -0.019 pp 0.00% -0.003 pp USD1.48 +9.5% 3 qtrs
23 MORGAN STANLEY 59.7K -181.7K (-75.3%) 96.7K -475.3K (-83.1%) 0.16% -0.490 pp 0.00% +0.000 pp USD3.20 -49.4% 8 qtrs
24 MAN GROUP PLC 56.5K +3.6K (+6.8%) 91.5K -33.8K (-27.0%) 0.15% +0.009 pp 0.00% 0.000 pp USD2.32 -30.2% 2 qtrs
25 BBR PARTNERS, LLC 53.4K +— (+0.0%) 86.5K -40.1K (-31.6%) 0.14% -0.001 pp 0.00% -0.003 pp USD3.61 -55.1% 5 qtrs
26 FORTITUDE ADVISORY GROUP L.L.C. 38.7K +— (+0.0%) 62.8K -29.1K (-31.6%) 0.10% -0.001 pp 0.03% -0.023 pp USD3.51 -53.8% 5 qtrs
27 QUADRATURE CAPITAL LTD 33.9K +33.9K (+100.0%) 54.9K +54.9K (+100.0%) 0.09% +0.091 pp 0.00% +0.001 pp USD1.62 +0.0% 1 qtrs NEW
28 PANAGORA ASSET MANAGEMENT INC 32.6K +32.6K (+100.0%) 52.8K +52.8K (+100.0%) 0.09% +0.087 pp 0.00% +0.000 pp USD1.62 +0.0% 1 qtrs NEW
29 POINT72 ASSET MANAGEMENT, L.P. 26.6K +26.6K (+100.0%) 43.1K +43.1K (+100.0%) 0.07% +0.071 pp 0.00% +0.000 pp USD1.62 +0.0% 1 qtrs NEW
30 UBS GROUP AG 25.1K +1.6K (+6.9%) 40.7K -15.0K (-27.0%) 0.07% +0.004 pp 0.00% +0.000 pp USD2.14 -24.3% 8 qtrs
31 DYNAMIC TECHNOLOGY LAB PRIVATE LTD 23.8K -3.4K (-12.6%) 38.0K -26.0K (-40.6%) 0.06% -0.010 pp 0.01% -0.002 pp USD2.37 -31.6% 2 qtrs
32 VANGUARD PERSONALIZED INDEXING MANAGEMENT, LLC 16.3K -5.2K (-24.3%) 26.4K -24.6K (-48.2%) 0.04% -0.014 pp 0.00% 0.000 pp USD2.61 -37.9% 5 qtrs
33 DIMENSIONAL FUND ADVISORS LP 13.8K +13.8K (+100.0%) 22.3K +22.3K (+100.0%) 0.04% +0.037 pp 0.00% +0.000 pp USD1.62 +0.0% 1 qtrs NEW
34 TWO SIGMA SECURITIES, LLC 11.7K -489.0 (-4.0%) 19.0K -9.9K (-34.4%) 0.03% -0.002 pp 0.00% -0.002 pp USD2.37 -31.6% 2 qtrs
35 LPL FINANCIAL LLC 11.3K +11.3K (+100.0%) 18.3K +18.3K (+100.0%) 0.03% +0.030 pp 0.00% +0.000 pp USD1.62 +0.0% 1 qtrs NEW
36 SQUAREPOINT OPS LLC 10.6K +10.6K (+100.0%) 17.2K +17.2K (+100.0%) 0.03% +0.028 pp 0.00% +0.000 pp USD1.62 +0.0% 3 qtrs
37 HRT FINANCIAL LP 11.1K -3.0K (-21.3%) 17.0K -16.0K (-48.5%) 0.03% -0.008 pp 0.00% 0.000 pp USD1.48 +9.5% 3 qtrs
38 TOWER RESEARCH CAPITAL LLC (TRC) 9.3K +9.3K (+100.0%) 15.1K +15.1K (+100.0%) 0.02% +0.025 pp 0.00% +0.000 pp USD1.62 +0.0% 8 qtrs
39 RUSSELL INVESTMENTS GROUP, LTD. 7.1K +— (+0.0%) 11.6K -5.4K (-31.6%) 0.02% 0.000 pp 0.00% +0.000 pp USD2.00 -19.0% 5 qtrs
40 FMR LLC 6.8K -3.4K (-33.2%) 11.0K -13.1K (-54.4%) 0.02% -0.009 pp 0.00% +0.000 pp USD2.30 -29.6% 6 qtrs
41 MEEDER ASSET MANAGEMENT INC 5.5K +— (+0.0%) 8.9K -4.1K (-31.6%) 0.01% 0.000 pp 0.00% 0.000 pp USD1.37 +18.2% 4 qtrs
42 US BANCORP \DE\ 4.5K +— (+0.0%) 7.3K -3.4K (-31.6%) 0.01% 0.000 pp 0.00% +0.000 pp USD10.82 -85.0% 8 qtrs
43 ADVISOR GROUP HOLDINGS, INC. 2.9K -250.0 (-8.0%) 4.7K -1.6K (-25.5%) 0.01% -0.001 pp 0.00% +0.000 pp USD1.73 -6.4% 6 qtrs
44 JPMORGAN CHASE & CO 1.6K -61.0K (-97.4%) 2.6K -145.7K (-98.3%) 0.00% -0.164 pp 0.00% +0.000 pp USD2.40 -32.5% 8 qtrs
45 MASSMUTUAL TRUST CO FSB/ADV 593.00 +— (+0.0%) 961.00 -444.0 (-31.6%) 0.00% +0.000 pp 0.00% +0.000 pp USD1.48 +9.5% 3 qtrs
46 NISA INVESTMENT ADVISORS, LLC 511.00 +— (+0.0%) 828.00 -383.0 (-31.6%) 0.00% +0.000 pp 0.00% +0.000 pp USD3.26 -50.3% 6 qtrs
47 JONES FINANCIAL COMPANIES LLLP 500.00 +— (+0.0%) 810.00 -335.0 (-29.3%) 0.00% +0.000 pp 0.00% +0.000 pp USD1.36 +19.1% 4 qtrs
48 ALLWORTH FINANCIAL LP 500.00 +500.0 (+100.0%) 810.00 +810.0 (+100.0%) 0.00% +0.001 pp 0.00% +0.000 pp USD1.62 +0.0% 1 qtrs NEW
49 BNP PARIBAS ARBITRAGE, SNC 307.00 -14.9K (-98.0%) 497.00 -35.5K (-98.6%) 0.00% -0.040 pp 0.00% +0.000 pp USD2.41 -32.8% 7 qtrs
50 LARSON FINANCIAL GROUP LLC 50.00 +— (+0.0%) 81.00 -38.0 (-31.9%) 0.00% +0.000 pp 0.00% +0.000 pp USD5.10 -68.2% 8 qtrs
51 BANK OF AMERICA CORP /DE/ 42.00 -18.7K (-99.8%) 68.00 -44.4K (-99.8%) 0.00% -0.050 pp 0.00% +0.000 pp USD2.60 -37.7% 8 qtrs
52 OPTIVER HOLDING B.V. 18.00 +— (+0.0%) 29.00 -14.0 (-32.6%) 0.00% +0.000 pp 0.00% +0.000 pp USD2.33 -30.5% 2 qtrs
53 SRS CAPITAL ADVISORS, INC. 11.00 -19.0 (-63.3%) 18.00 -53.0 (-74.6%) 0.00% 0.000 pp 0.00% +0.000 pp USD2.36 -31.4% 2 qtrs
54 BARCLAYS PLC 3.00 -8.7K (-100.0%) 5.00 -18.9K (-100.0%) 0.00% -0.023 pp 0.00% +0.000 pp USD2.33 -30.5% 7 qtrs
55 GREEN ALPHA ADVISORS, LLC -14.3K (-100.0%) -33.8K (-100.0%) 0.00% -0.038 pp 0.00% -0.033 pp USD 6 qtrs SOLD
56 CITIGROUP INC -3.3K (-100.0%) -7.9K (-100.0%) 0.00% -0.009 pp 0.00% +0.000 pp USD 8 qtrs SOLD
57 ROYAL BANK OF CANADA -615.0 (-100.0%) -1.0K (-100.0%) 0.00% -0.002 pp 0.00% +0.000 pp USD 7 qtrs SOLD
58 RIALTO WEALTH MANAGEMENT, LLC -305.0 (-100.0%) -723.0 (-100.0%) 0.00% -0.001 pp 0.00% 0.000 pp USD 3 qtrs SOLD
59 WALLEYE CAPITAL LLC -71.3K (-100.0%) -168.9K (-100.0%) 0.00% -0.192 pp 0.00% -0.001 pp USD 2 qtrs SOLD
60 MAREX GROUP PLC -15.0K (-100.0%) -34.5K (-100.0%) 0.00% -0.040 pp 0.00% 0.000 pp USD 3 qtrs SOLD
61 PRINCIPAL SECURITIES, INC. -544.0 (-100.0%) -1.3K (-100.0%) 0.00% -0.002 pp 0.00% +0.000 pp USD 8 qtrs SOLD
62 TANG CAPITAL MANAGEMENT LLC -28.0K (-100.0%) -66.4K (-100.0%) 0.00% -0.075 pp 0.00% -0.003 pp USD 4 qtrs SOLD
63 PHYSICIAN WEALTH ADVISORS, INC. -610.0 (-100.0%) -1.4K (-100.0%) 0.00% -0.002 pp 0.00% 0.000 pp USD 4 qtrs SOLD
64 JACOBS LEVY EQUITY MANAGEMENT, INC -34.2K (-100.0%) -81.0K (-100.0%) 0.00% -0.092 pp 0.00% 0.000 pp USD 7 qtrs SOLD
Ownership breakdown by holder

ETF Ownership

Top ETFs holding this stock Held by 12 ETFs in our universe
# ETF Weight Est. AUM exposure TER
1 iShares Micro-Cap ETF IWC 0.01% 121.3K 0.60%
2 Vanguard Extended Market ETF VXF 0.00% 419.3K 0.05%
3 Vanguard U.S. Total Market Shares Index ETF VTS.AX 0.00% 2.1K 0.03%
4 Vanguard U.S. Total Market Index ETF VUN.TO 0.00% 5.9K 0.17%
5 Vanguard U.S. Total Market Index ETF (CAD-hedged) VUS.TO 0.00% 433.38 0.17%
6 Vanguard Total Stock Market ETF VTI 0.00% 1.00M 0.03%
7 Vanguard All-Equity ETF Portfolio VEQT.TO 0.00% 2.2K 0.22%
8 Vanguard Growth ETF Portfolio VGRO.TO 0.00% 1.2K 0.22%
9 Vanguard Balanced ETF Portfolio VBAL.TO 0.00% 483.12 0.22%
10 Vanguard Conservative ETF Portfolio VCNS.TO 0.00% 53.23 0.22%

Insider Activity

Insider Activity — Latest Quarter
Ratio by transactions
0.00
Bearish
Buys
6
Sells
0
Shares acquired
569.0K
Shares disposed
Cash buys
Cash sales
Net activity
+569,000
Insider buys vs sells (history) From To
Recent insider transactions From To
Date Person Role Transaction A/D Security Shares Price Value Owned after D/I Filing
2026-04-01 Wein Matthew Officer A-Award A Common Stock 11,000 0.00 125,549 D
2026-04-01 Wapnick Pamela Officer A-Award A Common Stock 24,000 0.00 211,375 D
2026-04-01 Irish Jian Director / Officer A-Award A Common Stock 46,000 0.00 379,770 D
2026-03-05 Wein Matthew Officer S-Sale D Common Stock 482 1.60 771.20 114,549 D
2026-03-05 Wapnick Pamela Officer S-Sale D Common Stock 1,581 1.60 2.5K 187,375 D
2026-03-05 Irish Jian Director / Officer S-Sale D Common Stock 1,607 1.60 2.6K 333,770 D
2025-12-05 Wein Matthew Officer S-Sale D Common Stock 199 1.77 352.61 115,031 D
2025-12-05 Wapnick Pamela Officer S-Sale D Common Stock 1,576 1.77 2.8K 188,956 D
2025-12-05 Thomas Brian C. Director S-Sale D Common Stock 3,830 1.77 6.8K 2,510,960 D
2025-12-05 Irish Jian Director / Officer S-Sale D Common Stock 1,602 1.77 2.8K 563,839 D
2025-12-01 Wein Matthew Officer A-Award A Common Stock 96,000 1.60 153.6K 115,230 D
2025-12-01 Wapnick Pamela Officer A-Award A Common Stock 120,000 1.60 192.0K 190,532 D
2025-12-01 Irish Jian Director / Officer A-Award A Common Stock 211,000 1.60 337.6K 565,441 D
2025-09-05 Wein Matthew Officer S-Sale D Common Stock 199 1.81 360.19 19,230 D
2025-09-05 Wapnick Pamela Officer S-Sale D Common Stock 1,576 1.81 2.9K 70,532 D
2025-09-05 Thomas Brian C. Director S-Sale D Common Stock 2,701 1.81 4.9K 2,514,790 D
2025-09-05 Irish Jian Director / Officer S-Sale D Common Stock 1,602 1.81 2.9K 316,941 D
2025-09-02 Reid Laurence Director A-Award A Stock Option (Right to Buy) 42,000 1.82 76.4K 42,000 D
2025-08-11 Reid Laurence 0 0.00 0
2025-06-10 Eckhardt Juergen Director A-Award A Stock Option (Right to Buy) 21,000 1.57 33.0K 21,000 D
2025-06-10 Dere Willard H Director A-Award A Stock Option (Right to Buy) 21,000 1.57 33.0K 21,000 D
2025-06-10 BJERKHOLT ERIC Director A-Award A Stock Option (Right to Buy) 8,572 1.57 13.5K 8,572 D
2025-06-06 Wein Matthew Officer S-Sale D Common Stock 199 1.75 348.25 16,693 D
2025-06-06 Wapnick Pamela Officer S-Sale D Common Stock 1,576 1.75 2.8K 72,108 D
2025-06-06 Thomas Brian C. Director / Officer S-Sale D Common Stock 10,785 1.75 18.9K 2,517,491 D
2025-06-06 Noonberg Sarah B. Officer S-Sale D Common Stock 5,239 1.75 9.2K 109,135 D
2025-06-06 Irish Jian Director / Officer S-Sale D Common Stock 6,390 1.75 11.2K 315,543 D
2025-04-01 Wein Matthew Officer A-Award A Stock Option (Right to Buy) 22,725 1.32 30.0K 22,725 D
2025-04-01 Wapnick Pamela Officer A-Award A Common Stock 14,000 0.00 73,684 D
2025-04-01 Thomas Brian C. Director / Officer A-Award A Stock Option (Right to Buy) 196,000 1.32 258.7K 196,000 D
2025-04-01 Noonberg Sarah B. Officer A-Award A Common Stock 14,000 0.00 114,374 D
2025-04-01 Irish Jian Director / Officer A-Award A Stock Option (Right to Buy) 140,000 1.32 184.8K 140,000 D
2024-02-08 Novo Holdings A/S 10% Owner D SERIES B PREFERRED STOCK 147,415 0.00 0
2024-02-08 Noonberg Sarah B. Officer D Common Stock 0 0.00 42,611
2024-02-08 Borges Luis 0 0.00 0

Executive team

Top executives
EBIT / Employee
-4.8K
Shares Outstanding
37.62M

Executive compensation

Executive compensation (annual)
# Year Executive Salary Bonus Stock award Option award Incentive Other Total % Stock-
based
Filing
1 2025 Jian Irish, Ph.D., M.B.A. President and Chief Executive Officer 570.7K 428.0K 402.8K 252.6K 13.9K 1.67M 49.81%
2 2025 Brian C. Thomas, Ph.D. Former Chief Executive Officer 563.0K 42.2K 191.1K 599.7K 1.40M 16.71%
3 2025 Pamela Wapnick, M.B.A. Chief Financial Officer 464.0K 210.5K 81.9K 161.1K 17.5K 935.0K 31.27%
4 2025 Matthew L. Wein, J.D. General Counsel, Compliance Officer, Head of BD&L and Corporate Secretary 407.2K 163.4K 43.5K 124.9K 17.5K 756.4K 27.35%
5 2024 Brian C. Thomas, Ph.D. Former Chief Executive Officer 628.3K 1.29M 3.86M 265.2K 19.8K 6.06M 84.93%
6 2024 Brian C. Thomas, Ph.D. Chief Executive Officer 628.3K 1.29M 3.86M 265.2K 19.8K 6.06M 84.93%
7 2024 Jian Irish, Ph.D., M.B.A. President and Chief Executive Officer 536.3K 762.5K 2.29M 187.0K 11.3K 3.78M 80.58%
8 2024 Jian Irish, Ph.D., M.B.A. President and Chief Operating Officer 536.3K 762.5K 2.29M 187.0K 11.3K 3.78M 80.58%
9 2024 Pamela Wapnick, M.B.A. Chief Financial Officer 445.0K 750.0K 2.25M 122.4K 14.4K 3.58M 83.75%
10 2023 Brian C. Thomas, Ph.D. Chief Executive Officer 516.7K 20.0K 6.97M 288.6K 34.1K 7.83M 89.02%
11 2023 Jian Irish, Ph.D., M.B.A. President and Chief Operating Officer 465.0K 15.0K 1.78M 231.4K 18.4K 2.51M 70.96%
CEO compensation breakdown

Proxy statements

Proxy statements (DEF 14A)
Filing date Form type Filing
2026-04-27 DEFA14A
2026-04-27 DEF 14A
2025-04-28 DEFA14A
2025-04-28 DEF 14A

Recent SEC filings

Recent SEC filings
Filing date Form type Filing
2026-05-11 8-K
2026-05-11 10-Q
2026-04-27 DEFA14A
2026-04-27 DEF 14A
2026-04-27 ARS
2026-04-03 4
2026-04-03 4
2026-04-03 4
2026-03-09 4
2026-03-09 4

Executive team

NameTitleCompensationGender
Brian Charles Thomas Co-Founder & Director 1M
Jian Irish CEO, President & Director 837.2K
Pamela Wapnick Chief Financial Officer 642.6K female
Matthew L. Wein Gen­er­al Coun­sel, Com­pli­ance Offi­cer, Head of BD&L and Cor­po­rate Secretary 549.5K male
Katalin Kauser Senior Vice Pres­i­dent of Trans­la­tion­al Biol­o­gy female
Joseph Knowles Co-Founder & Member of Scientific Advisory Board
Alan Brooks Senior Vice President of Research
Mark Leonard Senior Vice Pres­i­dent of Tech­ni­cal Devel­op­ment & Oper­a­tions male
ESG Rating
B
BIOTECHNOLOGY
Rank: 226 out of 710
2026
E (Environmental)
61.6 / 56.3
Company / Sector avg.
S (Social)
63.2 / 62.4
Company / Sector avg.
G (Governance)
57.5 / 60.9
Company / Sector avg.
ESG Total
60.8 / 59.9
Company / Sector avg.
ESG Score History BIOTECHNOLOGY
Benchmark vs Sector
Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend history

Earnings history

Earnings reports

Stock splits