MeiraGTx Holdings plc (MGTX)
New York City, NY, US
MeiraGTx Holdings plc operates as a clinical-stage gene therapy company, dedicated to pioneering therapeutic solutions for individuals afflicted by serious illnesses. Its development efforts span a broad spectrum of conditions, encompassing ocular diseases like inherited forms of blindness, as well as xerostomia (dry mouth) that often follows radiation treatment for head and neck cancers. The company also targets various degenerative and neurodegenerative disorders, notably amyotrophic lateral sclerosis (ALS) and Parkinson's disease. Currently, several of its programs are in active clinical development, including Phase 1/2 trials for Achromatopsia, X-Linked Retinitis Pigmentosa, RPE65-deficiency, radiation-induced Xerostomia, and Parkinson's. MeiraGTx is also preparing to commence a clinical program for xerostomia linked to Sjogren's syndrome and maintains preclinical initiatives for other neurodegenerative conditions. A key collaboration exists with Janssen Pharmaceuticals, Inc. to advance regulatable gene therapy treatments, leveraging MeiraGTx's proprietary riboswitch technology. Established in 2015, MeiraGTx Holdings plc is headquartered in New York, New York.
Based on only 2 articles — low confidence
No mergers or acquisitions recorded for this company.
| Indicator | 1D | 1W | 2W | 3W | 1M |
|---|
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
| 1D | 5D | 1M | 3M | 6M | YTD | 1Y | 3Y | 5Y | 10Y | Max |
|---|---|---|---|---|---|---|---|---|---|---|
| -5.53% | -4.47% | -7.11% | +24.01% | +19.29% | +18.24% | +82.52% | +22.08% | -28.84% | -37.33% | -37.33% |
Revenue flow
Revenue by geography
Revenue by segment
Revenue composition
By product
By geography
Income Statement
Balance Sheet
Cash Flow Statement
Key Metrics
Financial Ratios
Employees
Financial Growth (CAGR)
Market Data
| Rating | 2026-05 | Change |
|---|---|---|
| Strong Buy | 2 | 0 |
| Buy | 6 | 0 |
| Hold | 0 | 0 |
| Sell | 0 | 0 |
| Strong Sell | 0 | 0 |
| Period | # Analysts | Avg Target |
|---|---|---|
| Last Month | 1 |
24.00
+93.4%
|
| Last Quarter | 2 |
25.00
+101.5%
|
| Last Year | 4 |
21.50
+73.2%
|
| All Time | 5 |
19.00
+53.1%
|
-
Revenue growth Biotechnology: +1.6%+144.6% ★ Q1'26: -84.8% (vs Q1'25)
-
EPS growth Biotechnology: +29.7%+33.0% ★ Q1'26: -11.8% (vs Q1'25)
-
FCF margin FCF growth · Biotechnology: +16.2%-110.7% Q1'26: +5,393.2% (vs Q1'25)
-
EBIT margin Biotechnology: +0.0%-130.2% Q1'26: -13,930.7% (vs Q1'25)
-
ROIC Biotechnology: -16.1%-624.7% Q1'26: +387.5% (vs Q1'25)
-
Share dilution Biotechnology: -3.4%+15.2% Q1'26: +2.9% (vs Q1'25)
-
Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×-0.84× Q1'26: -0.58× (vs Q1'25)
* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.
| Metric |
Dec 2019 actual |
Dec 2020 actual |
Dec 2021 actual |
Dec 2022 actual |
Dec 2023 actual |
Dec 2024 actual |
Dec 2025 actual |
Dec 2026 5 Rev. Ana. 5 EPS Ana. |
Dec 2027 5 Rev. Ana. 5 EPS Ana. |
Dec 2028 3 Rev. Ana. 3 EPS Ana. |
Dec 2029 2 Rev. Ana. 1 EPS Ana. |
Dec 2030 1 Rev. Ana. 1 EPS Ana. |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue |
13.29M
est: 6.50M (+104.5%)
|
15.56M
est: 17.16M (-9.3%)
|
37.70M
est: 22.77M (+65.5%)
|
15.92M
est: 32.75M (-51.4%)
|
14.02M
est: 8.12M (+72.6%)
|
33.28M
est: 16.51M (+101.5%)
|
81.39M
est: 24.51M (+232.1%)
|
49.47M
365.5K – 183.50M
+101.9% YoY
|
97.33M
7.99M – 213.38M
+96.8% YoY
|
100.20M
6.46M – 257.34M
+2.9% YoY
|
265.59M
17.13M – 682.10M
+165.1% YoY
|
557.77M
35.98M – 1.43B
+110.0% YoY
|
| EBITDA |
-52.46M
est: -6.50M (-707.1%)
|
-53.68M
est: -17.16M (-212.9%)
|
-71.40M
est: -22.77M (-213.5%)
|
-116.07M
est: -32.75M (-254.4%)
|
-57.05M
est: -8.12M (-602.4%)
|
-121.69M
est: -16.51M (-636.9%)
|
-105.97M
est: -24.51M (-332.4%)
|
-49.47M
-183.50M – -365.5K
-101.9% YoY
|
-97.33M
-213.38M – -7.99M
-96.8% YoY
|
-100.20M
-257.34M – -6.46M
-2.9% YoY
|
-265.59M
-682.10M – -17.13M
-165.1% YoY
|
-557.77M
-1.43B – -35.98M
-110.0% YoY
|
| EBIT |
-54.70M
est: -6.50M (-741.5%)
|
-57.85M
est: -17.16M (-237.2%)
|
-79.27M
est: -22.77M (-248.1%)
|
-124.67M
est: -32.75M (-280.7%)
|
-70.78M
est: -8.12M (-771.5%)
|
-134.52M
est: -16.51M (-714.6%)
|
-105.97M
est: -24.51M (-332.4%)
|
-49.47M
-183.50M – -365.5K
-101.9% YoY
|
-97.33M
-213.38M – -7.99M
-96.8% YoY
|
-100.20M
-257.34M – -6.46M
-2.9% YoY
|
-265.59M
-682.10M – -17.13M
-165.1% YoY
|
-557.77M
-1.43B – -35.98M
-110.0% YoY
|
| Net Income |
-54.75M
est: -141.51M (+61.3%)
|
-57.99M
est: -110.42M (+47.5%)
|
-79.56M
est: -143.83M (+44.7%)
|
-129.62M
est: -124.54M (-4.1%)
|
-84.03M
est: -93.14M (+9.8%)
|
-147.79M
est: -157.51M (+6.2%)
|
-114.20M
est: -120.53M (+5.3%)
|
-171.95M
-206.89M – -51.51M
-42.7% YoY
|
-82.32M
-188.15M – 23.52M
+52.1% YoY
|
-139.12M
-173.29M – -104.95M
-69.0% YoY
|
-45.04M
-136.87M – 9.74M
+67.6% YoY
|
86.86M
-18.77M – 263.96M
+292.9% YoY
|
| SGA |
46.68M
est: 15.51M (+201.1%)
|
44.21M
est: 40.93M (+8.0%)
|
43.77M
est: 54.33M (-19.4%)
|
46.55M
est: 78.12M (-40.4%)
|
47.29M
est: 15.82M (+199.0%)
|
54.22M
est: 32.16M (+68.6%)
|
52.90M
est: 47.73M (+10.8%)
|
96.34M
711.8K – 357.38M
+101.9% YoY
|
189.56M
15.57M – 415.57M
+96.8% YoY
|
195.15M
12.59M – 501.19M
+2.9% YoY
|
517.25M
33.37M – 1.33B
+165.1% YoY
|
1.09B
70.08M – 2.79B
+110.0% YoY
|
| EPS |
-1.58
est: -2.03 (+22.0%)
|
-1.43
est: -1.58 (+9.6%)
|
-1.80
est: -2.06 (+12.6%)
|
-2.87
est: -2.69 (-6.8%)
|
-1.49
est: -1.49 (-0.1%)
|
-2.12
est: -1.95 (-8.7%)
|
-1.42
est: -1.70 (+16.3%)
|
-1.78
-2.57 – -0.64
-4.9% YoY
|
-1.59
-2.34 – 0.29
+10.7% YoY
|
-1.75
-2.15 – -1.30
-10.3% YoY
|
-0.56
-1.70 – 0.12
+68.1% YoY
|
1.08
-0.23 – 3.28
+292.9% YoY
|
| Date | Firm | Previous | New Grade | Action |
|---|---|---|---|---|
| 2026-04-22 | Piper Sandler | Overweight | Overweight | Maintain |
| 2026-04-17 | RBC Capital | Outperform | Outperform | Maintain |
| Date | Rating | Overall | DCF | ROE | ROA | D/E | P/E | P/B |
|---|---|---|---|---|---|---|---|---|
| 2026-05-11 | C | 2/5 | 1/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 |
| 2026-05-08 | C | 2/5 | 1/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 |
| 2026-05-07 | C | 2/5 | 1/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 |
| 2026-05-06 | C | 2/5 | 1/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 |
| 2026-05-05 | C | 2/5 | 1/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 |
| 2026-05-04 | C | 2/5 | 1/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 |
| 2026-05-01 | C | 2/5 | 1/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 |
| 2026-04-30 | C | 2/5 | 1/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 |
| 2026-04-29 | C | 2/5 | 1/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 |
| 2026-04-28 | C | 2/5 | 1/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 |
| 2026-04-27 | C | 2/5 | 1/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 |
| 2026-04-24 | C | 2/5 | 1/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 |
| 2026-04-23 | C | 2/5 | 1/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 |
| 2026-04-22 | C | 2/5 | 1/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 |
| 2026-04-21 | C | 2/5 | 1/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 |
| 2026-04-20 | C | 2/5 | 1/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 |
| 2026-04-17 | C | 2/5 | 1/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 |
| 2026-04-16 | C | 2/5 | 1/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 |
| 2026-04-15 | C | 2/5 | 1/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 |
Owner Earnings
Ownership Overview
| # | Reporting person | Amount owned | % of class | Sole voting | Shared voting | Sole dispositive | Shared dispositive | Type | Citizenship | Filing date | SEC filing |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | EIN: 22-1024240 | 6.64M | 13.70% | — | 6.64M | — | 6.64M | CO | New Jersey | 2022-11-14 | ↗ |
| 2 | Joseph Edelman | 6.02M | 18.10% | — | 6.02M | — | 10.00 | IN | United States of America | 2019-03-05 | ↗ |
| 3 | Perceptive Advisors LLC | 6.02M | 18.10% | — | 6.02M | — | 10.00 | IA | Delaware | 2019-03-05 | ↗ |
| 4 | Perceptive Life Sciences Master Fund, Ltd. | 6.02M | 18.10% | — | 6.02M | — | 10.00 | CO | Cayman Islands | 2019-03-05 | ↗ |
| 5 | SANOFI | 4.70M | 7.40% | 4.70M | — | 4.70M | — | CO | The Republic of France | 2023-11-06 | ↗ |
| 6 | W. Lawrence Hawkins | 4.08M | 6.90% | 2.0K | 4.08M | 2.0K | 4.08M | HC, IN | Delaware | 2023-05-15 | ↗ |
| 7 | Prosight Management, LP | 4.08M | 6.90% | — | 4.08M | — | 4.08M | IA | Delaware | 2023-05-15 | ↗ |
| 8 | Prosight Partners, LLC | 4.08M | 6.90% | — | 4.08M | — | 4.08M | OO | Delaware | 2023-05-15 | ↗ |
| 9 | OrbiMed Capital LLC | 3.59M | 8.10% | 3.59M | — | 3.59M | — | IA | Delaware | 2022-02-11 | ↗ |
| 10 | Kadmon Corporation, LLC | 3.53M | 12.90% | 3.53M | — | 3.53M | — | CO | Delaware | 2019-02-08 | ↗ |
| 11 | Kadmon Holdings, Inc. | 3.53M | 12.90% | — | 3.53M | — | — | CO | Delaware | 2019-02-08 | ↗ |
| 12 | EIN: 22-1024240 | 2.90M | 8.70% | — | 2.90M | — | — | CO | New Jersey | 2019-03-04 | ↗ |
| 13 | Adage Capital Advisors, L.L.C. | 2.86M | 6.44% | — | 2.86M | — | — | OO | Delaware | 2022-02-10 | ↗ |
| 14 | Adage Capital Partners GP, L.L.C. | 2.86M | 6.44% | — | 2.86M | — | — | OO | Delaware | 2022-02-10 | ↗ |
| 15 | Adage Capital Partners, L.P. | 2.86M | 6.44% | — | 2.86M | — | — | PN | Delaware | 2022-02-10 | ↗ |
| 16 | Phillip Gross | 2.86M | 6.44% | — | 2.86M | — | — | IN | Delaware | 2022-02-10 | ↗ |
| 17 | Robert Atchinson | 2.86M | 6.44% | — | 2.86M | — | — | IN | Delaware | 2022-02-10 | ↗ |
| 18 | Adena Estate Inc. | 2.09M | 5.70% | 2.09M | — | 2.09M | — | CO | NUMBER OF | 2020-03-02 | ↗ |
| 19 | Inc. | 1.98M | 5.40% | — | 1.98M | — | 1.98M | CO | Maryland | 2020-02-14 | ↗ |
| 20 | Alexandria Real Estate Equities, Inc. | 1.98M | 4.50% | — | 1.98M | — | — | CO | Maryland | 2022-02-11 | ↗ |
| 21 | Alexandria Venture Investments, LLC | 1.98M | 4.50% | — | 1.98M | — | — | OO | Delaware | 2022-02-11 | ↗ |
| 22 | Prosight Plus Fund, LP | 1.05M | 1.80% | — | 1.05M | — | 1.05M | PN | Delaware | 2023-05-15 | ↗ |
| 23 | Prosight Fund, LP | 401.4K | 0.70% | — | 401.4K | — | 401.4K | PN | Delaware | 2023-05-15 | ↗ |
| 24 | OrbiMed Advisors LLC | 133.5K | 0.30% | — | 133.5K | — | — | IA | Delaware | 2022-02-11 | ↗ |
| 25 | Advisors LLC | 4.2K | 0.01% | — | 4.2K | — | — | IA | Delaware | 2020-02-14 | ↗ |
Institutional Activity (13F)
| # | Investor | Shares / Δ | Mkt value / Δ | Own% / Δ | Weight% / Δ | Avg px / Perf. | Hold / Status |
|---|---|---|---|---|---|---|---|
| 1 | — | 32.9K +32.9K (+100.0%) | 261.91M +261.9M (+100.0%) | 0.04% +0.041 pp | 0.10% +0.103 pp | USD7.95 +0.0% | 1 qtrs NEW |
| 2 | SANOFI | 12.20M +— (+0.0%) | 96.97M -3.4M (-3.4%) | 15.07% -0.068 pp | 31.24% -7.318 pp | USD6.09 +30.5% | 5 qtrs — |
| 3 | PERCEPTIVE ADVISORS LLC | 10.33M -2.3M (-18.2%) | 82.09M -21.7M (-20.9%) | 12.76% -2.911 pp | 1.46% -1.534 pp | USD9.99 -20.4% | 31 qtrs — |
| 4 | JOHNSON & JOHNSON | 6.64M +— (+0.0%) | 52.80M -1.9M (-3.4%) | 8.20% -0.037 pp | 9.51% -1.278 pp | USD9.43 -15.7% | 18 qtrs — |
| 5 | RUBRIC CAPITAL MANAGEMENT LP | 6.18M +2.4M (+65.7%) | 49.09M +18.4M (+60.1%) | 7.63% +3.005 pp | 0.59% +0.241 pp | USD7.16 +11.0% | 4 qtrs — |
| 6 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 4.00M -184.6K (-4.4%) | 31.80M -2.6M (-7.7%) | 4.94% -0.251 pp | 0.05% -0.006 pp | USD11.75 -32.3% | 28 qtrs — |
| 7 | PROSIGHT MANAGEMENT, LP | 3.21M -879.7K (-21.5%) | 25.52M -8.1M (-24.2%) | 3.97% -1.110 pp | 5.27% -2.576 pp | USD6.80 +16.9% | 30 qtrs — |
| 8 | MILLENNIUM MANAGEMENT LLC | 3.18M +615.4K (+24.0%) | 25.25M +4.2M (+19.8%) | 3.92% +0.746 pp | 0.01% +0.002 pp | USD7.75 +2.6% | 16 qtrs — |
| 9 | BLACKROCK, INC. | 3.07M +295.6K (+10.7%) | 24.41M +1.6M (+6.9%) | 3.79% +0.350 pp | 0.00% +0.000 pp | USD4.81 +65.3% | 6 qtrs — |
| 10 | 683 CAPITAL MANAGEMENT, LLC | 2.56M -65.9K (-2.5%) | 20.34M -1.3M (-5.8%) | 3.16% -0.096 pp | 0.89% -0.244 pp | USD10.90 -27.1% | 30 qtrs — |
| 11 | MORGAN STANLEY | 1.83M +587.3K (+47.3%) | 14.54M +4.3M (+42.3%) | 2.26% +0.719 pp | 0.00% +0.000 pp | USD7.81 +1.8% | 31 qtrs — |
| 12 | KNOLL CAPITAL MANAGEMENT, LLC | 1.25M +— (+0.0%) | 9.94M -350.0K (-3.4%) | 1.54% -0.007 pp | 4.56% -0.955 pp | USD4.17 +90.6% | 6 qtrs — |
| 13 | ERSTE ASSET MANAGEMENT GMBH | 789.7K +80.0K (+11.3%) | 6.28M +420.3K (+7.2%) | 0.98% +0.095 pp | 0.05% -0.004 pp | USD10.24 -22.4% | 17 qtrs — |
| 14 | STATE STREET CORP | 729.4K +48.4K (+7.1%) | 5.80M +194.2K (+3.5%) | 0.90% +0.056 pp | 0.00% +0.000 pp | USD14.45 -45.0% | 29 qtrs — |
| 15 | 22NW, LP | 586.5K +— (+0.0%) | 4.66M -164.2K (-3.4%) | 0.72% -0.003 pp | 1.96% -0.312 pp | USD6.52 +21.9% | 3 qtrs — |
| 16 | GEODE CAPITAL MANAGEMENT, LLC | 573.8K +18.5K (+3.3%) | 4.56M -8.7K (-0.2%) | 0.71% +0.020 pp | 0.00% +0.000 pp | USD10.75 -26.0% | 30 qtrs — |
| 17 | LONG FOCUS CAPITAL MANAGEMENT, LLC | 524.7K +— (+0.0%) | 4.17M -146.9K (-3.4%) | 0.65% -0.003 pp | 0.11% -0.033 pp | USD6.39 +24.4% | 5 qtrs — |
| 18 | VANGUARD GROUP INC | 494.8K +30.8K (+6.6%) | 3.93M +115.1K (+3.0%) | 0.61% +0.036 pp | 0.00% +0.000 pp | USD11.01 -27.8% | 29 qtrs — |
| 19 | GOLDMAN SACHS GROUP INC | 456.7K +196.5K (+75.5%) | 3.63M +1.5M (+69.6%) | 0.56% +0.241 pp | 0.00% +0.000 pp | USD7.48 +6.3% | 28 qtrs — |
| 20 | OPALEYE MANAGEMENT INC. | 390.8K +390.8K (+100.0%) | 3.11M +3.1M (+100.0%) | 0.48% +0.483 pp | 0.41% +0.410 pp | USD7.95 +0.0% | 1 qtrs NEW |
| 21 | D. E. SHAW & CO., INC. | 381.8K +208.6K (+120.4%) | 3.04M +1.6M (+112.9%) | 0.47% +0.257 pp | 0.00% +0.001 pp | USD8.08 -1.6% | 9 qtrs — |
| 22 | J. GOLDMAN & CO LP | 319.7K -1.5M (-82.2%) | 2.54M -12.3M (-82.9%) | 0.39% -1.840 pp | 0.07% -0.306 pp | USD6.03 +31.8% | 8 qtrs — |
| 23 | HENNION & WALSH ASSET MANAGEMENT, INC. | 308.5K +199.5K (+183.1%) | 2.45M +1.6M (+173.5%) | 0.38% +0.246 pp | 0.08% +0.052 pp | USD7.69 +3.4% | 3 qtrs — |
| 24 | WOODLINE PARTNERS LP | 300.3K +100.0K (+49.9%) | 2.39M +738.9K (+44.8%) | 0.37% +0.122 pp | 0.01% +0.002 pp | USD8.14 -2.3% | 5 qtrs — |
| 25 | JEFFERIES FINANCIAL GROUP INC. | 298.2K +298.2K (+100.0%) | 2.37M +2.4M (+100.0%) | 0.37% +0.368 pp | 0.01% +0.012 pp | USD7.95 +0.0% | 1 qtrs NEW |
| 26 | STEMPOINT CAPITAL LP | 287.7K +205.8K (+251.4%) | 2.29M +1.6M (+239.5%) | 0.36% +0.254 pp | 0.39% +0.257 pp | USD8.03 -1.0% | 2 qtrs — |
| 27 | NORTHERN TRUST CORP | 258.2K -12.7K (-4.7%) | 2.05M -176.7K (-7.9%) | 0.32% -0.017 pp | 0.00% +0.000 pp | USD12.23 -35.0% | 30 qtrs — |
| 28 | UBS GROUP AG | 222.0K +140.4K (+172.1%) | 1.77M +1.1M (+162.8%) | 0.27% +0.173 pp | 0.00% +0.000 pp | USD7.46 +6.6% | 31 qtrs — |
| 29 | BANK OF AMERICA CORP /DE/ | 208.5K +10.2K (+5.2%) | 1.66M +26.0K (+1.6%) | 0.26% +0.012 pp | 0.00% +0.000 pp | USD6.50 +22.3% | 31 qtrs — |
| 30 | PRIVIUM FUND MANAGEMENT B.V. | 200.0K +37.0K (+22.7%) | 1.59M +248.5K (+18.5%) | 0.25% +0.045 pp | 0.29% +0.052 pp | USD5.96 +33.4% | 8 qtrs — |
| 31 | ROYCE & ASSOCIATES LP | 176.1K +176.1K (+100.0%) | 1.40M +1.4M (+100.0%) | 0.22% +0.218 pp | 0.01% +0.014 pp | USD7.95 +0.0% | 22 qtrs — |
| 32 | CITADEL ADVISORS LLC | 143.4K -61.4K (-30.0%) | 1.14M -545.7K (-32.4%) | 0.18% -0.077 pp | 0.00% 0.000 pp | USD6.33 +25.6% | 26 qtrs — |
| 33 | NUVEEN, LLC | 131.1K +— (+0.0%) | 1.04M -36.7K (-3.4%) | 0.16% -0.001 pp | 0.00% +0.000 pp | USD6.78 +17.3% | 4 qtrs — |
| 34 | WELLINGTON MANAGEMENT GROUP LLP | 130.6K -11.1K (-7.8%) | 1.04M -128.1K (-11.0%) | 0.16% -0.015 pp | 0.00% +0.000 pp | USD6.68 +19.0% | 9 qtrs — |
| 35 | BNP PARIBAS ARBITRAGE, SNC | 128.0K +119.1K (+1,332.2%) | 1.02M +944.0K (+1,283.5%) | 0.16% +0.147 pp | 0.00% +0.000 pp | USD7.88 +0.9% | 29 qtrs — |
| 36 | BLAIR WILLIAM & CO/IL | 125.4K -7.1K (-5.4%) | 996.9K -93.8K (-8.6%) | 0.15% -0.010 pp | 0.00% 0.000 pp | USD23.69 -66.4% | 17 qtrs — |
| 37 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 111.4K +7.4K (+7.1%) | 885.8K +29.4K (+3.4%) | 0.14% +0.009 pp | 0.00% +0.000 pp | USD11.96 -33.5% | 28 qtrs — |
| 38 | AQR CAPITAL MANAGEMENT LLC | 108.0K +230.0 (+0.2%) | 858.7K -28.4K (-3.2%) | 0.13% 0.000 pp | 0.00% 0.000 pp | USD6.74 +18.0% | 4 qtrs — |
| 39 | BANK OF NEW YORK MELLON CORP | 101.1K -4.7K (-4.5%) | 803.7K -67.1K (-7.7%) | 0.12% -0.006 pp | 0.00% +0.000 pp | USD12.48 -36.3% | 28 qtrs — |
| 40 | JANE STREET GROUP, LLC | 98.2K -6.3K (-6.0%) | 781.0K -79.0K (-9.2%) | 0.12% -0.008 pp | 0.00% +0.000 pp | USD8.23 -3.4% | 2 qtrs — |
| 41 | BARCLAYS PLC | 95.7K -52.1K (-35.2%) | 761.1K +144.6K (+23.5%) | 0.12% -0.065 pp | 0.00% +0.000 pp | USD7.15 +11.2% | 30 qtrs — |
| 42 | RUSSELL INVESTMENTS GROUP, LTD. | 95.7K +12.9K (+15.5%) | 761.0K +79.2K (+11.6%) | 0.12% +0.015 pp | 0.00% +0.000 pp | USD6.04 +31.6% | 17 qtrs — |
| 43 | PLATINUM INVESTMENT MANAGEMENT LTD | 93.9K -33.6K (-26.4%) | 746.7K -302.9K (-28.9%) | 0.12% -0.042 pp | 0.17% +0.105 pp | USD4.17 +90.6% | 6 qtrs — |
| 44 | INVESCO LTD. | 90.9K +21.4K (+30.8%) | 722.5K +150.5K (+26.3%) | 0.11% +0.026 pp | 0.00% +0.000 pp | USD7.45 +6.7% | 19 qtrs — |
| 45 | EXODUSPOINT CAPITAL MANAGEMENT, LP | 86.9K +44.0K (+102.3%) | 691.1K +337.4K (+95.4%) | 0.11% +0.054 pp | 0.01% +0.002 pp | USD8.09 -1.7% | 2 qtrs — |
| 46 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 76.9K +38.3K (+99.1%) | 611.4K +293.5K (+92.3%) | 0.10% +0.047 pp | 0.00% +0.000 pp | USD7.01 +13.4% | 6 qtrs — |
| 47 | KENNEDY CAPITAL MANAGEMENT LLC | 70.7K +1.5K (+2.2%) | 562.4K -7.5K (-1.3%) | 0.09% +0.002 pp | 0.01% -0.001 pp | USD6.81 +16.7% | 8 qtrs — |
| 48 | DAVENPORT & CO LLC | 69.2K +14.0K (+25.4%) | 550.1K +95.8K (+21.1%) | 0.09% +0.017 pp | 0.00% +0.001 pp | USD10.68 -25.6% | 17 qtrs — |
| 49 | TREXQUANT INVESTMENT LP | 67.5K +67.5K (+100.0%) | 536.9K +536.9K (+100.0%) | 0.08% +0.083 pp | 0.00% +0.005 pp | USD7.95 +0.0% | 1 qtrs NEW |
| 50 | TOCQUEVILLE ASSET MANAGEMENT L.P. | 66.4K +7.2K (+12.2%) | 527.9K +40.7K (+8.3%) | 0.08% +0.009 pp | 0.01% +0.001 pp | USD10.72 -25.8% | 17 qtrs — |
| 51 | FORT SHERIDAN ADVISORS LLC | 65.6K -64.0 (-0.1%) | 521.3K -18.9K (-3.5%) | 0.08% 0.000 pp | 0.07% -0.004 pp | USD14.16 -43.9% | 28 qtrs — |
| 52 | Y-INTERCEPT (HONG KONG) LTD | 65.6K +65.6K (+100.0%) | 521.2K +521.2K (+100.0%) | 0.08% +0.081 pp | 0.01% +0.012 pp | USD7.95 +0.0% | 1 qtrs NEW |
| 53 | QUANTINNO CAPITAL MANAGEMENT LP | 60.8K +3.5K (+6.2%) | 483.0K +12.0K (+2.5%) | 0.08% +0.004 pp | 0.00% 0.000 pp | USD6.84 +16.2% | 3 qtrs — |
| 54 | RAYMOND JAMES FINANCIAL INC | 57.2K +57.2K (+100.0%) | 455.0K +455.0K (+100.0%) | 0.07% +0.071 pp | 0.00% +0.000 pp | USD7.95 +0.0% | 3 qtrs — |
| 55 | JACOBS LEVY EQUITY MANAGEMENT, INC | 56.2K +56.2K (+100.0%) | 447.1K +447.1K (+100.0%) | 0.07% +0.070 pp | 0.00% +0.002 pp | USD7.95 +0.0% | 1 qtrs NEW |
| 56 | RHUMBLINE ADVISERS | 56.2K -4.5K (-7.4%) | 446.8K -52.5K (-10.5%) | 0.07% -0.006 pp | 0.00% +0.000 pp | USD11.40 -30.3% | 28 qtrs — |
| 57 | ALLIANCEBERNSTEIN L.P. | 54.6K +— (+0.0%) | 434.0K -15.3K (-3.4%) | 0.07% 0.000 pp | 0.00% +0.000 pp | USD13.22 -39.9% | 27 qtrs — |
| 58 | BROWN ADVISORY INC | 50.0K +— (+0.0%) | 397.5K -14.0K (-3.4%) | 0.06% 0.000 pp | 0.00% +0.000 pp | USD6.52 +21.9% | 3 qtrs — |
| 59 | WELLS FARGO & COMPANY/MN | 49.8K +22.5K (+82.3%) | 395.8K +171.1K (+76.1%) | 0.06% +0.028 pp | 0.00% +0.000 pp | USD6.99 +13.7% | 12 qtrs — |
| 60 | STATE OF WISCONSIN INVESTMENT BOARD | 42.6K +— (+0.0%) | 339.0K -11.9K (-3.4%) | 0.05% 0.000 pp | 0.00% +0.000 pp | USD8.02 -0.9% | 27 qtrs — |
| 61 | DEUTSCHE BANK AG\ | 40.7K +7.4K (+22.2%) | 323.7K +49.4K (+18.0%) | 0.05% +0.009 pp | 0.00% +0.000 pp | USD9.18 -13.4% | 30 qtrs — |
| 62 | XTX TOPCO LTD | 38.0K +3.8K (+11.0%) | 302.3K +20.3K (+7.2%) | 0.05% +0.005 pp | 0.01% -0.007 pp | USD8.20 -3.0% | 2 qtrs — |
| 63 | JUMP FINANCIAL, LLC | 37.0K -33.6K (-47.6%) | 294.2K -286.9K (-49.4%) | 0.05% -0.042 pp | 0.00% -0.003 pp | USD8.23 -3.4% | 4 qtrs — |
| 64 | LETKO, BROSSEAU & ASSOCIATES INC | 32.0K +— (+0.0%) | 254.4K -9.0K (-3.4%) | 0.04% 0.000 pp | 0.00% 0.000 pp | USD5.15 +54.4% | 10 qtrs — |
| 65 | VIRTUS INVESTMENT ADVISERS, INC. | 29.8K +29.8K (+100.0%) | 237.1K +237.1K (+100.0%) | 0.04% +0.037 pp | 0.06% +0.064 pp | USD7.95 +0.0% | 1 qtrs NEW |
| 66 | ALPHACENTRIC ADVISORS LLC | 28.5K +28.5K (+100.0%) | 226.5K +226.5K (+100.0%) | 0.04% +0.035 pp | 0.23% +0.226 pp | USD7.95 +0.0% | 1 qtrs NEW |
| 67 | ENGINEERS GATE MANAGER LP | 26.8K +26.8K (+100.0%) | 213.4K +213.4K (+100.0%) | 0.03% +0.033 pp | 0.00% +0.003 pp | USD7.95 +0.0% | 1 qtrs NEW |
| 68 | CREATIVEONE WEALTH, LLC | 26.4K -5.2K (-16.3%) | 210.1K -49.8K (-19.2%) | 0.03% -0.007 pp | 0.01% -0.001 pp | USD5.17 +53.8% | 12 qtrs — |
| 69 | SKYVIEW INVESTMENT ADVISORS, LLC | 24.0K +— (+0.0%) | 191.0K -7.0K (-3.5%) | 0.03% 0.000 pp | 0.02% -0.001 pp | USD4.10 +93.9% | 7 qtrs — |
| 70 | JPMORGAN CHASE & CO | 23.9K -36.4K (-60.4%) | 190.4K -306.7K (-61.7%) | 0.03% -0.045 pp | 0.00% +0.000 pp | USD7.68 +3.5% | 30 qtrs — |
| 71 | HSBC HOLDINGS PLC | 23.8K +4.6K (+24.3%) | 188.7K +30.6K (+19.3%) | 0.03% +0.006 pp | 0.00% +0.000 pp | USD6.49 +22.5% | 8 qtrs — |
| 72 | PRICE T ROWE ASSOCIATES INC /MD/ | 22.8K +— (+0.0%) | 182.0K -6.0K (-3.2%) | 0.03% 0.000 pp | 0.00% +0.000 pp | USD5.11 +55.6% | 7 qtrs — |
| 73 | FOX RUN MANAGEMENT, L.L.C. | 22.5K -479.0 (-2.1%) | 178.8K -10.2K (-5.4%) | 0.03% -0.001 pp | 0.03% -0.002 pp | USD8.23 -3.4% | 2 qtrs — |
| 74 | SG AMERICAS SECURITIES, LLC | 22.4K -7.6K (-25.5%) | 178.0K -69.0K (-27.9%) | 0.03% -0.010 pp | 0.00% -0.001 pp | USD8.23 -3.4% | 6 qtrs — |
| 75 | MITSUBISHI UFJ KOKUSAI ASSET MANAGEMENT CO., LTD. | 22.6K +22.6K (+100.0%) | 176.3K +176.3K (+100.0%) | 0.03% +0.028 pp | 0.00% +0.000 pp | USD7.95 +0.0% | 1 qtrs NEW |
| 76 | MIRAE ASSET GLOBAL ETFS HOLDINGS LTD. | 21.0K +2.0K (+10.3%) | 167.0K +10.3K (+6.6%) | 0.03% +0.002 pp | 0.00% +0.000 pp | USD4.90 +62.2% | 7 qtrs — |
| 77 | BEACON POINTE ADVISORS, LLC | 20.8K +— (+0.0%) | 165.1K -5.8K (-3.4%) | 0.03% 0.000 pp | 0.00% 0.000 pp | USD8.23 -3.4% | 2 qtrs — |
| 78 | METLIFE INVESTMENT MANAGEMENT, LLC | 20.0K -4.2K (-17.2%) | 159.3K -39.9K (-20.0%) | 0.02% -0.005 pp | 0.00% 0.000 pp | USD7.30 +8.9% | 28 qtrs — |
| 79 | VOLEON CAPITAL MANAGEMENT LP | 16.6K +16.6K (+100.0%) | 131.9K +131.9K (+100.0%) | 0.02% +0.021 pp | 0.00% +0.003 pp | USD7.95 +0.0% | 1 qtrs NEW |
| 80 | INTECH INVESTMENT MANAGEMENT LLC | 16.0K +— (+0.0%) | 127.3K -4.5K (-3.4%) | 0.02% 0.000 pp | 0.00% +0.000 pp | USD6.43 +23.6% | 5 qtrs — |
| 81 | CITIGROUP INC | 15.6K +2.1K (+15.9%) | 123.6K +13.2K (+12.0%) | 0.02% +0.003 pp | 0.00% +0.000 pp | USD6.04 +31.6% | 30 qtrs — |
| 82 | CREATIVE PLANNING | 15.4K -1.1K (-6.9%) | 122.8K -13.7K (-10.0%) | 0.02% -0.002 pp | 0.00% +0.000 pp | USD7.11 +11.8% | 4 qtrs — |
| 83 | PERIGON WEALTH MANAGEMENT, LLC | 15.0K +15.0K (+100.0%) | 119.3K +119.3K (+100.0%) | 0.02% +0.019 pp | 0.00% +0.002 pp | USD7.95 +0.0% | 1 qtrs NEW |
| 84 | CIBC PRIVATE WEALTH GROUP, LLC | 15.0K +— (+0.0%) | 119.3K -4.2K (-3.4%) | 0.02% 0.000 pp | 0.00% +0.000 pp | USD4.91 +61.9% | 10 qtrs — |
| 85 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 14.9K -577.0 (-3.7%) | 118.4K -8.9K (-7.0%) | 0.02% -0.001 pp | 0.00% +0.000 pp | USD12.78 -37.8% | 27 qtrs — |
| 86 | FMR LLC | 13.8K +8.3K (+150.3%) | 109.9K +64.4K (+141.8%) | 0.02% +0.010 pp | 0.00% +0.000 pp | USD7.16 +11.0% | 16 qtrs — |
| 87 | CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD. | 13.1K -985.0 (-7.0%) | 104.3K -11.8K (-10.1%) | 0.02% -0.001 pp | 0.01% -0.002 pp | USD5.42 +46.7% | 14 qtrs — |
| 88 | ABEL HALL, LLC | 12.3K +12.3K (+100.0%) | 97.7K +97.7K (+100.0%) | 0.02% +0.015 pp | 0.02% +0.023 pp | USD7.95 +0.0% | 1 qtrs NEW |
| 89 | STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 12.2K +— (+0.0%) | 97.3K -3.4K (-3.4%) | 0.02% 0.000 pp | 0.00% +0.000 pp | USD15.30 -48.0% | 19 qtrs — |
| 90 | HOBBS GROUP ADVISORS, LLC | 12.0K -2.3K (-15.9%) | 95.0K -21.9K (-18.8%) | 0.01% -0.003 pp | 0.03% -0.008 pp | USD6.52 +21.9% | 3 qtrs — |
| 91 | PROSHARE ADVISORS LLC | 11.8K +11.8K (+100.0%) | 93.7K +93.7K (+100.0%) | 0.01% +0.015 pp | 0.00% +0.000 pp | USD7.95 +0.0% | 8 qtrs — |
| 92 | POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY | 11.7K +— (+0.0%) | 92.7K -3.3K (-3.4%) | 0.01% 0.000 pp | 0.00% +0.000 pp | USD6.09 +30.5% | 5 qtrs — |
| 93 | ROYAL BANK OF CANADA | 10.9K -289.5K (-96.4%) | 87.0K -2.4M (-96.5%) | 0.01% -0.359 pp | 0.00% 0.000 pp | USD6.50 +22.3% | 27 qtrs — |
| 94 | LEVIN CAPITAL STRATEGIES, L.P. | 10.0K -15.0K (-60.0%) | 79.5K -126.3K (-61.4%) | 0.01% -0.019 pp | 0.01% -0.012 pp | USD6.52 +21.9% | 3 qtrs — |
| 95 | CWM, LLC | 7.8K -67.0 (-0.9%) | 62.0K -3.0K (-4.6%) | 0.01% 0.000 pp | 0.00% +0.000 pp | USD6.70 +18.7% | 6 qtrs — |
| 96 | NEW YORK STATE COMMON RETIREMENT FUND | 7.3K +— (+0.0%) | 57.7K -2.0K (-3.4%) | 0.01% +0.000 pp | 0.00% +0.000 pp | USD21.57 -63.1% | 29 qtrs — |
| 97 | ROCKEFELLER CAPITAL MANAGEMENT L.P. | 6.1K +630.0 (+11.5%) | 48.7K +3.5K (+7.7%) | 0.01% +0.001 pp | 0.00% +0.000 pp | USD8.20 -3.0% | 2 qtrs — |
| 98 | LEGAL & GENERAL GROUP PLC | 4.3K -139.0 (-3.1%) | 34.0K -2.3K (-6.4%) | 0.01% 0.000 pp | 0.00% +0.000 pp | USD10.65 -25.4% | 30 qtrs — |
| 99 | STATE OF ALASKA, DEPARTMENT OF REVENUE | 4.0K +— (+0.0%) | 32.0K -1.0K (-3.0%) | 0.01% +0.000 pp | 0.00% +0.000 pp | USD8.23 -3.4% | 2 qtrs — |
Insider Activity
| Date | Person | Role | Transaction | A/D | Security | Shares | Price | Value | Owned after | D/I | Filing |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026-04-21 | Giroux Richard | Officer | S-Sale | D | Ordinary Shares | 56,000 | 10.22 | 572.3K | 971,530 | D | ↗ |
| 2026-04-17 | PERCEPTIVE ADVISORS LLC | Director / 10% Owner | A-Award | A | Ordinary Shares | 555,555 | 9.00 | 5.00M | 10,786,658 | I | ↗ |
| 2026-04-07 | Naylor Stuart | Officer | S-Sale | D | Ordinary Shares | 27,661 | 9.36 | 258.9K | 668,505 | D | ↗ |
| 2026-03-25 | PERCEPTIVE ADVISORS LLC | Director / 10% Owner | A-Award | A | Warrant (Right to Buy) | 400,000 | 8.00 | 3.20M | 400,000 | I | ↗ |
| 2026-03-24 | Forbes Alexandria | Director / Officer | S-Sale | D | Ordinary Shares | 62,000 | 7.41 | 459.4K | 1,449,695 | D | ↗ |
| 2026-02-21 | Zeldin Robert K | Officer | M-Exempt | D | Restricted Share Units | 7,500 | 0.00 | — | 7,500 | D | ↗ |
| 2026-02-21 | Wollin Robert J | Officer | M-Exempt | D | Restricted Share Units | 11,250 | 0.00 | — | 11,250 | D | ↗ |
| 2026-02-21 | Naylor Stuart | Officer | F-InKind | D | Ordinary Shares | 11,750 | 7.45 | 87.5K | 696,166 | D | ↗ |
| 2026-02-21 | Giroux Richard | Officer | M-Exempt | D | Restricted Share Units | 60,000 | 0.00 | — | 60,000 | D | ↗ |
| 2026-02-21 | Forbes Alexandria | Director / Officer | M-Exempt | A | Ordinary Shares | 62,500 | 0.00 | — | 1,544,743 | D | ↗ |
| 2026-01-17 | Zeldin Robert K | Officer | M-Exempt | D | Restricted Share Units | 35,000 | 0.00 | — | 35,000 | D | ↗ |
| 2026-01-17 | Wollin Robert J | Officer | M-Exempt | D | Restricted Share Units | 50,000 | 0.00 | — | 50,000 | D | ↗ |
| 2026-01-17 | Naylor Stuart | Officer | F-InKind | D | Ordinary Shares | 35,250 | 7.42 | 261.6K | 682,916 | D | ↗ |
| 2026-01-17 | Giroux Richard | Officer | M-Exempt | D | Restricted Share Units | 310,000 | 0.00 | — | 310,000 | D | ↗ |
| 2026-01-17 | Forbes Alexandria | Director / Officer | M-Exempt | D | Restricted Share Units | 310,000 | 0.00 | — | 310,000 | D | ↗ |
| 2026-01-07 | Zeldin Robert K | Officer | F-InKind | D | Ordinary Shares | 7,814 | 7.73 | 60.4K | 146,204 | D | ↗ |
| 2026-01-07 | Wollin Robert J | Officer | M-Exempt | D | Restricted Share Units | 7,500 | 0.00 | — | 0 | D | ↗ |
| 2026-01-07 | Naylor Stuart | Officer | M-Exempt | A | Ordinary Shares | 37,500 | 0.00 | — | 660,791 | D | ↗ |
| 2026-01-07 | Giroux Richard | Officer | M-Exempt | D | Restricted Share Units | 52,500 | 0.00 | — | 0 | D | ↗ |
| 2026-01-07 | Forbes Alexandria | Director / Officer | M-Exempt | A | Ordinary Shares | 62,500 | 0.00 | — | 1,370,233 | D | ↗ |
| 2025-12-31 | PERCEPTIVE ADVISORS LLC | Director / 10% Owner | D-Return | D | Ordinary Shares | 2,300,000 | 7.91 | 18.19M | 10,231,103 | I | ↗ |
| 2025-12-23 | Forbes Alexandria | Director / Officer | G-Gift | D | Ordinary Shares | 6,250 | 0.00 | — | 1,307,733 | D | ↗ |
| 2025-11-20 | Wollin Robert J | Officer | G-Gift | D | Ordinary Shares | 5,000 | 0.00 | — | 26,146 | D | ↗ |
| 2025-10-21 | Giroux Richard | Officer | S-Sale | D | Ordinary Shares | 24,000 | 8.87 | 212.9K | 829,494 | D | ↗ |
| 2025-10-07 | Forbes Alexandria | Director / Officer | S-Sale | D | Ordinary Shares | 47,500 | 8.39 | 398.5K | 1,313,983 | D | ↗ |
| 2025-07-22 | Giroux Richard | Officer | S-Sale | D | Ordinary Shares | 24,000 | 8.52 | 204.5K | 853,494 | D | ↗ |
| 2025-07-08 | Forbes Alexandria | Director / Officer | S-Sale | D | Ordinary Shares | 47,500 | 7.97 | 378.6K | 1,361,483 | D | ↗ |
| 2025-06-30 | Giroux Richard | Officer | G-Gift | D | Ordinary Shares | 5,000 | 0.00 | — | 877,494 | D | ↗ |
| 2025-06-12 | Yu Debra | Director | A-Award | A | Restricted Share Units | 45,000 | 0.00 | — | 45,000 | D | ↗ |
| 2025-06-12 | Seligman Nicole | Director | A-Award | A | Restricted Share Units | 45,000 | 0.00 | — | 45,000 | D | ↗ |
| 2025-06-12 | SHENK THOMAS E | Director | A-Award | A | Restricted Share Units | 45,000 | 0.00 | — | 45,000 | D | ↗ |
| 2025-06-12 | PERCEPTIVE ADVISORS LLC | Director / 10% Owner | A-Award | A | Restricted Share Units | 45,000 | 0.00 | — | 45,000 | I | ↗ |
| 2025-06-12 | Mendoza Neil | Director | A-Award | A | Restricted Share Units | 45,000 | 0.00 | — | 45,000 | D | ↗ |
| 2025-06-12 | Hukkelhoven Ellen | Director | A-Award | A | Restricted Share Units | 45,000 | 0.00 | — | 45,000 | D | ↗ |
| 2025-06-12 | Harris Keith R. | Director | A-Award | A | Restricted Share Units | 75,000 | 0.00 | — | 75,000 | D | ↗ |
| 2025-06-06 | Harris Keith R. | Director | M-Exempt | D | Restricted Share Units | 75,000 | 0.00 | — | 0 | D | ↗ |
| 2025-04-22 | Giroux Richard | Officer | S-Sale | D | Ordinary Shares | 24,000 | 6.00 | 144.0K | 882,494 | D | ↗ |
| 2025-04-08 | Forbes Alexandria | Director / Officer | S-Sale | D | Ordinary Shares | 47,500 | 5.34 | 253.7K | 1,408,983 | D | ↗ |
| 2025-04-03 | Zeldin Robert K | Officer | A-Award | A | Restricted Share Units | 90,000 | 0.00 | — | 90,000 | D | ↗ |
| 2025-04-03 | Wollin Robert J | Officer | A-Award | A | Restricted Share Units | 100,000 | 0.00 | — | 100,000 | D | ↗ |
| 2025-04-03 | Naylor Stuart | Officer | A-Award | A | Restricted Share Units | 100,000 | 0.00 | — | 100,000 | D | ↗ |
| 2025-04-03 | Giroux Richard | Officer | A-Award | A | Restricted Share Units | 950,000 | 0.00 | — | 950,000 | D | ↗ |
| 2025-04-03 | Forbes Alexandria | Director / Officer | A-Award | A | Restricted Share Units | 950,000 | 0.00 | — | 950,000 | D | ↗ |
| 2025-02-21 | Zeldin Robert K | Officer | M-Exempt | D | Restricted Share Units | 15,000 | 0.00 | — | 15,000 | D | ↗ |
| 2025-02-21 | Wollin Robert J | Officer | M-Exempt | D | Restricted Share Units | 22,500 | 0.00 | — | 22,500 | D | ↗ |
| 2025-02-21 | Naylor Stuart | Officer | F-InKind | D | Ordinary Shares | 23,500 | 7.30 | 171.6K | 623,291 | D | ↗ |
| 2025-02-21 | Giroux Richard | Officer | M-Exempt | D | Restricted Share Units | 120,000 | 0.00 | — | 120,000 | D | ↗ |
| 2025-02-21 | Forbes Alexandria | Director / Officer | M-Exempt | D | Restricted Share Units | 125,000 | 0.00 | — | 125,000 | D | ↗ |
| 2025-01-21 | Giroux Richard | Officer | S-Sale | D | Ordinary Shares | 24,000 | 6.29 | 151.0K | 849,947 | D | ↗ |
| 2025-01-14 | Zeldin Robert K | Officer | M-Exempt | D | Restricted Share Units | 37,500 | 0.00 | — | 0 | D | ↗ |
| 2025-01-14 | Wollin Robert J | Officer | M-Exempt | D | Restricted Share Units | 5,000 | 0.00 | — | 0 | D | ↗ |
| 2025-01-14 | Naylor Stuart | Officer | M-Exempt | A | Ordinary Shares | 23,750 | 0.00 | — | 607,954 | D | ↗ |
| 2025-01-14 | Giroux Richard | Officer | M-Exempt | D | Restricted Share Units | 25,000 | 0.00 | — | 0 | D | ↗ |
| 2025-01-14 | Forbes Alexandria | Director / Officer | M-Exempt | A | Ordinary Shares | 30,000 | 0.00 | — | 1,413,441 | D | ↗ |
| 2025-01-08 | Forbes Alexandria | Director / Officer | S-Sale | D | Ordinary Shares | 11,661 | 6.30 | 73.5K | 1,383,441 | D | ↗ |
| 2025-01-07 | Zeldin Robert K | Officer | M-Exempt | A | Ordinary Shares | 17,500 | 0.00 | — | 111,958 | D | ↗ |
| 2025-01-07 | Wollin Robert J | Officer | M-Exempt | D | Restricted Share Units | 7,500 | 0.00 | — | 7,500 | D | ↗ |
| 2025-01-07 | Naylor Stuart | Officer | M-Exempt | D | Restricted Share Units | 37,500 | 0.00 | — | 37,500 | D | ↗ |
| 2025-01-07 | Giroux Richard | Officer | M-Exempt | D | Restricted Share Units | 52,500 | 0.00 | — | 52,500 | D | ↗ |
| 2025-01-07 | Forbes Alexandria | Director / Officer | M-Exempt | D | Restricted Share Units | 62,500 | 0.00 | — | 62,500 | D | ↗ |
| 2024-08-12 | Sanofi | 10% Owner | — | I | Ordinary Shares ($0.00003881 par value per share) | 0 | 0.00 | — | 11,500,000 | — | ↗ |
| 2024-08-12 | PERCEPTIVE ADVISORS LLC | Director / 10% Owner | P-Purchase | A | Ordinary Shares | 1,250,000 | 4.00 | 5.00M | 12,531,103 | — | ↗ |
| 2024-06-06 | Yu Debra | Director | A-Award | A | Restricted Share Units | 45,000 | 0.00 | — | 45,000 | — | ↗ |
| 2024-06-06 | Seligman Nicole | Director | A-Award | A | Restricted Share Units | 45,000 | 0.00 | — | 45,000 | — | ↗ |
| 2024-06-06 | SHENK THOMAS E | Director | A-Award | A | Restricted Share Units | 45,000 | 0.00 | — | 45,000 | — | ↗ |
| 2024-06-06 | PERCEPTIVE ADVISORS LLC | Director / 10% Owner | A-Award | A | Restricted Share Units | 45,000 | 0.00 | — | 45,000 | — | ↗ |
| 2024-06-06 | Mendoza Neil | Director | A-Award | A | Restricted Share Units | 45,000 | 0.00 | — | 45,000 | — | ↗ |
| 2024-06-06 | Indyk Martin | Director | A-Award | A | Restricted Share Units | 45,000 | 0.00 | — | 45,000 | — | ↗ |
| 2024-06-06 | Hukkelhoven Ellen | Director | A-Award | A | Restricted Share Units | 45,000 | 0.00 | — | 45,000 | — | ↗ |
| 2024-06-06 | Harris Keith R. | Director | A-Award | A | Restricted Share Units | 75,000 | 0.00 | — | 75,000 | — | ↗ |
| 2024-06-05 | Indyk Martin | Director | M-Exempt | A | Ordinary Shares | 20,000 | 0.00 | — | 35,000 | — | ↗ |
| 2024-06-05 | Harris Keith R. | Director | M-Exempt | A | Ordinary Shares | 30,000 | 0.00 | — | 50,000 | — | ↗ |
| 2024-05-28 | Giroux Richard | Officer | G-Gift | D | Ordinary Shares | 3,000 | 0.00 | — | 837,426 | — | ↗ |
| 2024-04-05 | Forbes Alexandria | Director / Officer | G-Gift | D | Ordinary Shares | 1,000 | 0.00 | — | 1,372,504 | — | ↗ |
| 2024-03-12 | Forbes Alexandria | Director / Officer | G-Gift | D | Ordinary Shares | 2,000 | 0.00 | — | 1,373,504 | — | ↗ |
| 2024-02-29 | Giroux Richard | Officer | G-Gift | D | Ordinary Shares | 13,500 | 0.00 | — | 840,426 | — | ↗ |
| 2024-01-17 | Zeldin Robert K | Officer | A-Award | A | Restricted Share Units | 70,000 | 0.00 | — | 70,000 | — | ↗ |
| 2024-01-17 | Wollin Robert J | Officer | A-Award | A | Restricted Share Units | 100,000 | 0.00 | — | 100,000 | — | ↗ |
| 2024-01-17 | Naylor Stuart | Officer | A-Award | A | Restricted Share Units | 150,000 | 0.00 | — | 150,000 | — | ↗ |
| 2024-01-17 | Giroux Richard | Officer | A-Award | A | Restricted Share Units | 620,000 | 0.00 | — | 620,000 | — | ↗ |
| 2024-01-17 | Forbes Alexandria | Director / Officer | A-Award | A | Restricted Share Units | 620,000 | 0.00 | — | 620,000 | — | ↗ |
| 2024-01-14 | Zeldin Robert K | Officer | M-Exempt | A | Ordinary Shares | 37,500 | 0.00 | — | 104,480 | — | ↗ |
| 2024-01-14 | Wollin Robert J | Officer | M-Exempt | D | Restricted Share Units | 5,000 | 0.00 | — | 5,000 | — | ↗ |
| 2024-01-14 | Naylor Stuart | Officer | M-Exempt | D | Restricted Share Units | 23,750 | 0.00 | — | 23,750 | — | ↗ |
| 2024-01-14 | Giroux Richard | Officer | M-Exempt | D | Restricted Share Units | 25,000 | 0.00 | — | 25,000 | — | ↗ |
| 2024-01-14 | Forbes Alexandria | Director / Officer | M-Exempt | D | Restricted Share Units | 30,000 | 0.00 | — | 30,000 | — | ↗ |
| 2024-01-08 | Naylor Stuart | Officer | F-InKind | D | Ordinary Shares | 18,800 | 6.63 | 124.6K | 551,742 | — | ↗ |
| 2024-01-08 | Giroux Richard | Officer | F-InKind | D | Ordinary Shares | 19,829 | 6.63 | 131.5K | 842,145 | — | ↗ |
| 2024-01-08 | Forbes Alexandria | Director / Officer | M-Exempt | D | Restricted Share Units | 48,750 | 0.00 | — | 0 | — | ↗ |
| 2024-01-07 | Zeldin Robert K | Officer | M-Exempt | D | Restricted Share Units | 35,000 | 0.00 | — | 35,000 | — | ↗ |
| 2024-01-07 | Wollin Robert J | Officer | M-Exempt | D | Restricted Share Units | 15,000 | 0.00 | — | 15,000 | — | ↗ |
| 2024-01-07 | Naylor Stuart | Officer | F-InKind | D | Ordinary Shares | 35,250 | 6.30 | 222.1K | 530,542 | — | ↗ |
| 2024-01-07 | Giroux Richard | Officer | M-Exempt | D | Restricted Share Units | 105,000 | 0.00 | — | 105,000 | — | ↗ |
| 2024-01-07 | Forbes Alexandria | Director / Officer | M-Exempt | A | Ordinary Shares | 125,000 | 0.00 | — | 1,404,489 | — | ↗ |
| 2023-09-15 | Johnson & Johnson Innovation - JJDC, Inc. | 10% Owner | — | D | Ordinary Shares | 0 | 0.00 | — | 6,641,064 | — | ↗ |
| 2023-06-08 | Yu Debra | Director | A-Award | A | Stock Option (right to buy) | 20,000 | 8.04 | 160.8K | 20,000 | — | ↗ |
| 2023-06-08 | Seligman Nicole | Director | A-Award | A | Restricted Share Units | 22,500 | 0.00 | — | 22,500 | — | ↗ |
| 2023-06-08 | SHENK THOMAS E | Director | A-Award | A | Restricted Share Units | 20,000 | 0.00 | — | 20,000 | — | ↗ |
| 2023-06-08 | PERCEPTIVE ADVISORS LLC | Director / 10% Owner | A-Award | A | Stock Option (right to buy) | 20,000 | 8.04 | 160.8K | 20,000 | — | ↗ |
| 2023-06-08 | Mendoza Neil | Director | A-Award | A | Stock Option (right to buy) | 20,000 | 8.04 | 160.8K | 20,000 | — | ↗ |
| 2023-06-08 | Indyk Martin | Director | A-Award | A | Restricted Share Units | 20,000 | 0.00 | — | 20,000 | — | ↗ |
| 2023-06-08 | Hukkelhoven Ellen | Director | A-Award | A | Stock Option (right to buy) | 20,000 | 8.04 | 160.8K | 20,000 | — | ↗ |
| 2023-06-08 | Harris Keith R. | Director | A-Award | A | Restricted Share Units | 30,000 | 0.00 | — | 30,000 | — | ↗ |
| 2023-06-07 | Indyk Martin | Director | M-Exempt | A | Ordinary Shares | 15,000 | 0.00 | — | 15,000 | — | ↗ |
| 2023-06-07 | Harris Keith R. | Director | M-Exempt | A | Ordinary Shares | 20,000 | 0.00 | — | 20,000 | — | ↗ |
| 2023-05-05 | PERCEPTIVE ADVISORS LLC | Director / 10% Owner | P-Purchase | A | Ordinary Shares | 4,347,826 | 5.75 | 25.00M | 11,281,103 | — | ↗ |
| 2023-02-21 | Zeldin Robert K | Officer | A-Award | A | Stock Option (Right to Buy) | 30,000 | 8.60 | 258.0K | 30,000 | — | ↗ |
| 2023-02-21 | Wollin Robert J | Officer | A-Award | A | Stock Option (Right to Buy) | 45,000 | 8.60 | 387.0K | 45,000 | — | ↗ |
| 2023-02-21 | Naylor Stuart | Officer | A-Award | A | Restricted Share Units | 100,000 | 0.00 | — | 100,000 | — | ↗ |
| 2023-02-21 | Giroux Richard | Officer | A-Award | A | Stock Option (Right to Buy) | 135,000 | 8.60 | 1.16M | 135,000 | — | ↗ |
| 2023-02-21 | Forbes Alexandria | Director / Officer | A-Award | A | Stock Option (Right to Buy) | 225,000 | 8.60 | 1.94M | 225,000 | — | ↗ |
| 2023-01-14 | Zeldin Robert K | Director / Officer | M-Exempt | A | Ordinary Shares | 75,000 | 0.00 | — | 80,000 | — | ↗ |
| 2023-01-14 | Wollin Robert J | Director | M-Exempt | A | Ordinary Shares | 10,000 | 0.00 | — | 11,000 | — | ↗ |
| 2023-01-14 | Naylor Stuart | Director / Officer | M-Exempt | A | Ordinary Shares | 47,500 | 0.00 | — | 513,117 | — | ↗ |
| 2023-01-14 | Giroux Richard | Director | F-InKind | D | Ordinary Shares | 26,438 | 6.99 | 184.8K | 774,994 | — | ↗ |
| 2023-01-14 | Forbes Alexandria | Director | M-Exempt | A | Ordinary Shares | 60,000 | 0.00 | — | 1,138,176 | — | ↗ |
| 2023-01-08 | Naylor Stuart | Director / Officer | M-Exempt | D | Restricted Share Units | 40,000 | 0.00 | — | 40,000 | — | ↗ |
| 2023-01-08 | Giroux Richard | Director | F-InKind | D | Ordinary Shares | 19,829 | 6.60 | 130.9K | 751,432 | — | ↗ |
| 2023-01-08 | Forbes Alexandria | Director | M-Exempt | D | Restricted Share Units | 48,750 | 0.00 | — | 48,750 | — | ↗ |
| 2022-12-31 | Forbes Alexandria | Director / Officer | — | I | Ordinary Shares | 0 | 0.00 | — | 175,000 | — | ↗ |
| 2022-11-09 | JOHNSON & JOHNSON | Director | — | I | Ordinary Shares | 0 | 0.00 | — | 6,641,064 | — | ↗ |
| 2022-08-02 | PERCEPTIVE ADVISORS LLC | Director / 10% Owner | A-Award | A | Warrant (Right to Buy) | 400,000 | 15.00 | 6.00M | 400,000 | I | ↗ |
| 2022-06-07 | Seligman Nicole | Director | A-Award | A | Stock Option (right to buy) | 15,000 | 0.00 | — | 15,000 | — | ↗ |
| 2022-06-07 | SHENK THOMAS E | Director | A-Award | A | Stock Option (right to buy) | 15,000 | 8.25 | 123.8K | 15,000 | — | ↗ |
| 2022-06-07 | PERCEPTIVE ADVISORS LLC | Director / 10% Owner | A-Award | A | Restricted Share Units | 15,000 | 0.00 | — | 15,000 | — | ↗ |
| 2022-06-07 | Mendoza Neil | Director | A-Award | A | Stock Option (right to buy) | 15,000 | 0.00 | — | 15,000 | — | ↗ |
| 2022-06-07 | MARCUS JOEL S | Director | A-Award | A | Stock Option (right to buy) | 15,000 | 0.00 | — | 15,000 | — | ↗ |
| 2022-06-07 | LEVINE ARNOLD J | Director | A-Award | A | Stock Option (right to buy) | 15,000 | 0.00 | — | 15,000 | — | ↗ |
| 2022-06-07 | Indyk Martin | Director | A-Award | A | Stock Option (right to buy) | 15,000 | 8.25 | 123.8K | 15,000 | — | ↗ |
| 2022-06-07 | Hukkelhoven Ellen | Director | A-Award | A | Stock Option (right to buy) | 15,000 | 0.00 | — | 15,000 | — | ↗ |
| 2022-06-07 | Harris Keith R. | Director | A-Award | A | Stock Option (right to buy) | 20,000 | 8.25 | 165.0K | 20,000 | — | ↗ |
| 2022-06-07 | EDELMAN JOSEPH | Director | A-Award | A | Restricted Share Units | 15,000 | 0.00 | — | 15,000 | — | ↗ |
| 2022-06-03 | Zeldin Robert K | Director / Officer | P-Purchase | A | Ordinary Shares | 6 | 7.89 | 47.34 | 5,000 | — | ↗ |
| 2022-05-25 | Wollin Robert J | Director | P-Purchase | A | Ordinary Shares | 1,000 | 7.94 | 7.9K | 1,000 | — | ↗ |
| 2022-04-25 | Yu Debra | — | — | — | — | 0 | 0.00 | — | 0 | — | ↗ |
| 2022-01-08 | Naylor Stuart | Officer | M-Exempt | D | Restricted Share Units | 80,000 | 0.00 | — | 80,000 | — | ↗ |
| 2022-01-08 | Giroux Richard | Officer | M-Exempt | D | Restricted Share Units | 75,000 | 0.00 | — | 75,000 | — | ↗ |
| 2022-01-08 | Forbes Alexandria | Director / Officer | M-Exempt | D | Restricted Share Units | 97,500 | 0.00 | — | 97,500 | — | ↗ |
| 2022-01-07 | Zeldin Robert K | Officer | A-Award | A | Stock Option (Right to Buy) | 30,000 | 21.53 | 645.9K | 30,000 | — | ↗ |
| 2022-01-07 | Wollin Robert J | Officer | A-Award | A | Stock Option (Right to Buy) | 30,000 | 21.53 | 645.9K | 30,000 | — | ↗ |
| 2022-01-07 | Naylor Stuart | Officer | A-Award | A | Restricted Share Units | 150,000 | 0.00 | — | 150,000 | — | ↗ |
| 2022-01-07 | Giroux Richard | Officer | A-Award | A | Restricted Share Units | 210,000 | 0.00 | — | 210,000 | — | ↗ |
| 2022-01-07 | Forbes Alexandria | Director / Officer | A-Award | A | Restricted Share Units | 250,000 | 0.00 | — | 250,000 | — | ↗ |
| 2021-12-31 | Giroux Richard | Officer | — | I | Ordinary Shares | 0 | 0.00 | — | 5,152 | — | ↗ |
| 2021-12-31 | Forbes Alexandria | Director / Officer | — | I | Ordinary Shares | 0 | 0.00 | — | 150,000 | — | ↗ |
| 2021-11-17 | Forbes Alexandria | Director / Officer | S-Sale | D | Ordinary Shares | 15,000 | 19.86 | 297.9K | 1,080,781 | — | ↗ |
| 2021-11-16 | Forbes Alexandria | Director / Officer | S-Sale | D | Ordinary Shares | 11,800 | 19.82 | 233.9K | 1,098,981 | — | ↗ |
| 2021-10-20 | Giroux Richard | Officer | S-Sale | D | Ordinary Shares | 13,744 | 20.93 | 287.7K | 826,174 | — | ↗ |
| 2021-10-19 | Giroux Richard | Officer | S-Sale | D | Ordinary Shares | 1,300 | 20.07 | 26.1K | 839,918 | — | ↗ |
| 2021-10-18 | Naylor Stuart | Officer | S-Sale | D | Ordinary Shares | 12,000 | 17.95 | 215.4K | 402,017 | — | ↗ |
| 2021-10-18 | Forbes Alexandria | Director / Officer | S-Sale | D | Ordinary Shares | 23,821 | 17.21 | 410.0K | 1,116,960 | — | ↗ |
| 2021-07-20 | Naylor Stuart | Officer | S-Sale | D | Ordinary Shares | 9,390 | 15.06 | 141.4K | 414,017 | — | ↗ |
| 2021-07-13 | Naylor Stuart | Officer | S-Sale | D | Ordinary Shares | 2,610 | 15.04 | 39.3K | 423,407 | — | ↗ |
| 2021-06-10 | Seligman Nicole | Director | A-Award | A | Stock Option (right to buy) | 15,000 | 14.88 | 223.2K | 15,000 | — | ↗ |
| 2021-06-10 | SHENK THOMAS E | Director | A-Award | A | Restricted Share Units | 15,000 | 0.00 | — | 15,000 | — | ↗ |
| 2021-06-10 | PERCEPTIVE ADVISORS LLC | Director / 10% Owner | A-Award | A | Stock Option (right to buy) | 15,000 | 14.88 | 223.2K | 15,000 | — | ↗ |
| 2021-06-10 | Mendoza Neil | Director | A-Award | A | Stock Option (right to buy) | 15,000 | 14.88 | 223.2K | 15,000 | — | ↗ |
| 2021-06-10 | MARCUS JOEL S | Director | A-Award | A | Restricted Share Units | 15,000 | 0.00 | — | 15,000 | — | ↗ |
| 2021-06-10 | LEVINE ARNOLD J | Director | A-Award | A | Stock Option (right to buy) | 15,000 | 14.88 | 223.2K | 15,000 | — | ↗ |
| 2021-06-10 | Indyk Martin | Director | A-Award | A | Stock Option (right to buy) | 15,000 | 14.88 | 223.2K | 15,000 | — | ↗ |
| 2021-06-10 | Hukkelhoven Ellen | Director | A-Award | A | Stock Option (right to buy) | 15,000 | 14.88 | 223.2K | 15,000 | — | ↗ |
| 2021-06-10 | Harris Keith R. | Director | A-Award | A | Stock Option (right to buy) | 20,000 | 14.88 | 297.6K | 20,000 | — | ↗ |
| 2021-06-09 | Forbes Alexandria | Director / Officer | S-Sale | D | Ordinary Shares | 4,153 | 15.04 | 62.5K | 1,290,781 | — | ↗ |
| 2021-06-08 | Naylor Stuart | Officer | S-Sale | D | Ordinary Shares | 5,040 | 15.01 | 75.7K | 426,017 | — | ↗ |
| 2021-06-08 | Forbes Alexandria | Director / Officer | S-Sale | D | Ordinary Shares | 20,180 | 15.02 | 303.1K | 1,294,934 | — | ↗ |
| 2021-06-07 | Naylor Stuart | Officer | S-Sale | D | Ordinary Shares | 1,042 | 15.02 | 15.7K | 431,057 | — | ↗ |
| 2021-06-07 | Forbes Alexandria | Director / Officer | S-Sale | D | Ordinary Shares | 5,667 | 15.03 | 85.2K | 1,315,114 | — | ↗ |
| 2021-04-30 | Naylor Stuart | Officer | S-Sale | D | Ordinary Shares | 741 | 15.01 | 11.1K | 432,099 | D | ↗ |
| 2021-04-29 | Naylor Stuart | Officer | S-Sale | D | Ordinary Shares | 1,405 | 15.02 | 21.1K | 432,840 | D | ↗ |
| 2021-04-28 | Naylor Stuart | Officer | S-Sale | D | Ordinary Shares | 3,772 | 15.14 | 57.1K | 434,245 | D | ↗ |
| 2021-03-15 | MARCUS JOEL S | Director | M-Exempt | A | Ordinary Shares | 12,882 | 7.72 | 99.4K | 12,882 | — | ↗ |
| 2021-03-05 | Forbes Alexandria | Director / Officer | G-Gift | D | Orindary Shares | 1,000 | 0.00 | — | 1,320,781 | — | ↗ |
| 2021-02-17 | Forbes Alexandria | Director / Officer | S-Sale | D | Ordinary Shares | 15,000 | 15.57 | 233.6K | 1,321,781 | — | ↗ |
| 2021-02-16 | Forbes Alexandria | Director / Officer | S-Sale | D | Ordinary Shares | 15,000 | 15.60 | 234.0K | 1,336,781 | — | ↗ |
| 2021-01-14 | Zeldin Robert K | Officer | A-Award | A | Stock Option (Right to Buy) | 40,000 | 16.43 | 657.2K | 40,000 | — | ↗ |
| 2021-01-14 | Wollin Robert J | Officer | A-Award | A | Restricted Share Units | 20,000 | 0.00 | — | 20,000 | — | ↗ |
| 2021-01-14 | Naylor Stuart | Officer | A-Award | A | Stock Option (Right to Buy) | 35,000 | 16.43 | 575.1K | 35,000 | — | ↗ |
| 2021-01-14 | Giroux Richard | Officer | A-Award | A | Restricted Share Units | 100,000 | 0.00 | — | 100,000 | — | ↗ |
| 2021-01-14 | Forbes Alexandria | Director / Officer | A-Award | A | Stock Option (Right to Buy) | 65,000 | 16.43 | 1.07M | 65,000 | — | ↗ |
| 2021-01-05 | Naylor Stuart | Officer | S-Sale | D | Ordinary Shares | 6,000 | 15.34 | 92.0K | 438,017 | — | ↗ |
| 2021-01-04 | Naylor Stuart | Officer | S-Sale | D | Ordinary Shares | 6,000 | 15.40 | 92.4K | 444,017 | — | ↗ |
| 2020-12-31 | Giroux Richard | Officer | — | I | Orindary Shares | 0 | 0.00 | — | 85,000 | — | ↗ |
| 2020-12-31 | Forbes Alexandria | Director / Officer | — | — | — | 0 | 0.00 | — | 0 | — | ↗ |
| 2020-12-17 | Giroux Richard | Officer | S-Sale | D | Ordinary Shares | 18,000 | 16.00 | 288.0K | 846,518 | — | ↗ |
| 2020-12-17 | Forbes Alexandria | Director / Officer | S-Sale | D | Ordinary Shares | 13,390 | 15.00 | 200.9K | 1,355,781 | — | ↗ |
| 2020-11-23 | PERCEPTIVE ADVISORS LLC | Director / 10% Owner | P-Purchase | A | Ordinary Shares | 500,000 | 12.85 | 6.43M | 6,933,277 | — | ↗ |
| 2020-11-18 | Forbes Alexandria | Director / Officer | S-Sale | D | Ordinary Shares | 1,610 | 15.05 | 24.2K | 1,369,171 | — | ↗ |
| 2020-11-17 | Forbes Alexandria | Director / Officer | S-Sale | D | Ordinary Shares | 15,000 | 15.17 | 227.6K | 1,370,781 | — | ↗ |
| 2020-11-12 | Forbes Alexandria | Director / Officer | S-Sale | D | Ordinary Shares | 7,851 | 15.01 | 117.8K | 1,388,748 | — | ↗ |
| 2020-11-11 | Forbes Alexandria | Director / Officer | S-Sale | D | Ordinary Shares | 2,698 | 15.02 | 40.5K | 1,394,672 | — | ↗ |
| 2020-11-10 | Naylor Stuart | Officer | S-Sale | D | Ordinary Shares | 3,739 | 15.00 | 56.1K | 451,129 | — | ↗ |
| 2020-11-10 | Forbes Alexandria | Director / Officer | S-Sale | D | Ordinary Shares | 12,703 | 15.05 | 191.2K | 1,399,097 | — | ↗ |
| 2020-11-09 | Naylor Stuart | Officer | S-Sale | D | Ordinary Shares | 512 | 15.00 | 7.7K | 454,868 | — | ↗ |
| 2020-11-05 | Naylor Stuart | Officer | S-Sale | D | Ordinary Shares | 8,282 | 15.02 | 124.4K | 455,380 | — | ↗ |
| 2020-11-05 | Forbes Alexandria | Director / Officer | S-Sale | D | Ordinary Shares | 3,981 | 15.03 | 59.8K | 1,411,800 | — | ↗ |
| 2020-10-05 | Naylor Stuart | Officer | S-Sale | D | Ordinary Shares | 301 | 15.00 | 4.5K | 463,662 | — | ↗ |
| 2020-08-12 | MARCUS JOEL S | Director | S-Sale | D | Ordinary Shares | 7,959 | 14.15 | 112.6K | 0 | — | ↗ |
| 2020-08-11 | MARCUS JOEL S | Director | S-Sale | D | Ordinary Shares | 7,500 | 13.86 | 104.0K | 7,959 | — | ↗ |
| 2020-08-10 | MARCUS JOEL S | Director | M-Exempt | A | Ordinary Shares | 15,459 | 5.63 | 87.0K | 15,459 | — | ↗ |
| 2020-08-03 | Zeldin Robert K | Officer | — | — | — | 0 | 0.00 | — | 0 | — | ↗ |
Executive team
Executive compensation
| # | Year | Executive | Salary | Bonus | Stock award | Option award | Incentive | Other | Total | % Stock- based |
Filing |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 2025 | Alexandria Forbes, Ph.D. President and Chief Executive Officer | 840.0K | 1.65M | 5.82M | — | — | 21.0K | 8.33M | 69.91% | ↗ |
| 2 | 2025 | Richard Giroux Chief Financial Officer and Chief Operating Officer | 714.0K | 1.59M | 5.82M | — | — | 21.0K | 8.15M | 71.47% | ↗ |
| 3 | 2025 | Robert K. Zeldin, M.D. Chief Medical Officer | 543.4K | 500.0K | 551.7K | — | — | 21.0K | 1.62M | 34.14% | ↗ |
| 4 | 2024 | Alexandria Forbes, Ph.D. President and Chief Executive Officer | 840.0K | 2.20M | 3.82M | — | — | 20.7K | 6.88M | 55.55% | ↗ |
| 5 | 2024 | Alexandria Forbes, Ph.D. President and Chief Executive Officer | 840.0K | 2.20M | 3.82M | — | — | 20.7K | 6.88M | 55.55% | ↗ |
| 6 | 2024 | Richard Giroux Chief Financial Officer and Chief Operating Officer | 714.0K | 2.14M | 3.82M | — | — | 20.7K | 6.69M | 57.05% | ↗ |
| 7 | 2024 | Richard Giroux Chief Financial Officer and Chief Operating Officer | 714.0K | 2.14M | 3.82M | — | — | 20.7K | 6.69M | 57.05% | ↗ |
| 8 | 2024 | Stuart Naylor, Ph.D. Chief Development Officer | 501.2K | 600.0K | 924.0K | — | — | — | 2.03M | 45.63% | ↗ |
| 9 | 2023 | Alexandria Forbes, Ph.D. President and Chief Executive Officer | 648.0K | 2.20M | 2.15M | 1.30M | — | 36.4K | 6.34M | 54.42% | ↗ |
| 10 | 2023 | Richard Giroux Chief Financial Officer and Chief Operating Officer | 544.0K | 1.58M | 2.06M | 779.0K | — | 19.8K | 4.98M | 57.07% | ↗ |
| 11 | 2023 | Stuart Naylor, Ph.D. Chief Development Officer | 462.1K | 600.0K | 860.0K | 577.0K | — | — | 2.50M | 57.50% | ↗ |
| 12 | 2022 | Alexandria Forbes, Ph.D. President and Chief Executive Officer | 580.0K | 1.72M | 5.38M | — | — | 37.7K | 7.72M | 69.77% | ↗ |
| 13 | 2022 | Richard Giroux Chief Financial Officer and Chief Operating Officer | 495.0K | 1.32M | 4.52M | — | — | 18.3K | 6.35M | 71.19% | ↗ |
| 14 | 2022 | Stuart Naylor, Ph.D. Chief Development Officer | 442.9K | 560.0K | 3.23M | — | — | — | 4.23M | 76.30% | ↗ |
| 15 | 2021 | Alexandria Forbes, Ph.D. President and Chief Executive Officer | 580.0K | 2.45M | 1.97M | 788.5K | — | 31.9K | 5.82M | 47.41% | ↗ |
| 16 | 2021 | Richard Giroux Chief Financial Officer and Chief Operating Officer | 495.0K | 1.88M | 1.64M | 485.2K | — | 17.4K | 4.52M | 47.08% | ↗ |
| 17 | 2021 | Robert K. Zeldin, M.D. | 480.0K | 600.0K | 2.46M | 485.2K | — | 17.4K | 4.05M | 72.88% | ↗ |
| 18 | 2021 | Stuart Naylor, Ph.D. Chief Development Officer | 453.8K | 800.0K | 1.56M | 424.6K | — | 45.4K | 3.28M | 60.45% | ↗ |
| 19 | 2020 | Alexandria Forbes, Ph.D. President and Chief Executive Officer | 602.3K | 1.86M | 3.96M | — | — | 1.84M | 8.26M | 47.94% | ↗ |
| 20 | 2020 | Richard Giroux Chief Financial Officer and Chief Operating Officer | 514.0K | 1.44M | 3.05M | — | — | 1.84M | 6.84M | 44.55% | ↗ |
| 21 | 2020 | Stuart Naylor, Ph.D. Chief Development Officer | 424.9K | 720.0K | 3.25M | — | — | 42.5K | 4.44M | 73.23% | ↗ |
| 22 | 2019 | Alexandria Forbes, Ph.D. President and Chief Executive Officer | 580.0K | 3.16M | — | — | — | 4.74M | 8.48M | 0.00% | ↗ |
| 23 | 2019 | Richard Giroux Chief Financial Officer and Chief Operating Officer | 495.0K | 2.25M | — | — | — | 4.73M | 7.47M | 0.00% | ↗ |
| 24 | 2019 | Bruce Gottlieb | 341.0K | 450.0K | — | 2.62M | — | — | 3.41M | 76.78% | ↗ |
| 25 | 2019 | Stuart Naylor, Ph.D. Chief Development Officer | 408.4K | 640.0K | — | — | — | 40.8K | 1.09M | 0.00% | ↗ |
| 26 | 2018 | Alexandria Forbes, Ph.D. President and Chief Executive Officer | 555.0K | 3.03M | 11.35M | 1.38M | — | 6.69M | 23.00M | 55.34% | ↗ |
| 27 | 2018 | Richard Giroux Chief Operating Officer | 476.7K | 2.43M | 11.35M | 1.17M | — | 6.67M | 22.10M | 56.64% | ↗ |
| 28 | 2018 | Richard Giroux Chief Financial Officer and Chief Operating Officer | 476.7K | 2.43M | 11.35M | 1.17M | — | 6.67M | 22.10M | 56.64% | ↗ |
| 29 | 2018 | Stuart Naylor, Ph.D. Chief Development Officer | 352.0K | 750.0K | — | 1.11M | — | 35.2K | 2.25M | 49.36% | ↗ |
| 30 | 2017 | Alexandria Forbes, Ph.D. President and Chief Executive Officer | 450.0K | 490.0K | — | 166.0K | — | 16.2K | 1.12M | 14.79% | ↗ |
| 31 | 2017 | Richard Giroux Chief Financial Officer and Chief Operating Officer | 400.0K | 440.0K | — | 153.2K | — | — | 993.2K | 15.43% | ↗ |
| 32 | 2017 | Richard Giroux Chief Operating Officer | 400.0K | 440.0K | — | 153.2K | — | — | 993.2K | 15.43% | ↗ |
| 33 | 2017 | Stuart Naylor, Ph.D. Chief Development Officer | 257.8K | 528.9K | — | 25.5K | — | 25.8K | 838.0K | 3.05% | ↗ |
Proxy statements
Recent SEC filings
Executive team
| Name | Title | Compensation | Gender |
|---|---|---|---|
| Alexandria Forbes | Chief Executive Officer, President & Director | 3M | — |
| Richard Brian Giroux | Chief Operating Officer & Chief Financial Officer | 2M | male |
| Stuart Naylor | Chief Development Officer | 1M | — |
| Robert K. Zeldin | Chief Medical Officer | 1M | — |
| Christine Elise Sheehy | Senior Vice President of Global Integration | — | female |
| David Rubinstein | Senior Vice President of Business Development | — | — |
| Tim Randall | Senior Vice President of Risk & Internal Controls | — | male |
| Robert J. Wollin | General Counsel & Secretary | — | male |
| Michel Michaelides | Head of Clinical Ophthalmology | — | — |
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Community Opinion for MGTX
Short-term intention
Target Price Distribution
These are community opinions and do not constitute buy or sell advice to act on. The results shown are based on aggregated opinions and are not an investment recommendation, nor do they intend to influence any investment decision.

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