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MeiraGTx Holdings plc (MGTX)

USD12.41 +0.07 (+0.57%)
US NASDAQ Healthcare Biotechnology
Address 430 East 29th Street 10016
New York City, NY, US
CEO Alexandria Forbes
IPO 2018-06-08
CIK 1735438 ISIN KYG596651029

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Description

MeiraGTx Holdings plc operates as a clinical-stage gene therapy company, dedicated to pioneering therapeutic solutions for individuals afflicted by serious illnesses. Its development efforts span a broad spectrum of conditions, encompassing ocular diseases like inherited forms of blindness, as well as xerostomia (dry mouth) that often follows radiation treatment for head and neck cancers. The company also targets various degenerative and neurodegenerative disorders, notably amyotrophic lateral sclerosis (ALS) and Parkinson's disease. Currently, several of its programs are in active clinical development, including Phase 1/2 trials for Achromatopsia, X-Linked Retinitis Pigmentosa, RPE65-deficiency, radiation-induced Xerostomia, and Parkinson's. MeiraGTx is also preparing to commence a clinical program for xerostomia linked to Sjogren's syndrome and maintains preclinical initiatives for other neurodegenerative conditions. A key collaboration exists with Janssen Pharmaceuticals, Inc. to advance regulatable gene therapy treatments, leveraging MeiraGTx's proprietary riboswitch technology. Established in 2015, MeiraGTx Holdings plc is headquartered in New York, New York.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
USD12.41 +0.07 (+0.57%)
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Volume Profile
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Liquidity & share structure
Average Volume
979.6K
Beta
1.26
Float Shares
66.63M
Free Float %
72.0%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
-5.53% -4.47% -7.11% +24.01% +19.29% +18.24% +82.52% +22.08% -28.84% -37.33% -37.33%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
vs.
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Analyst Consensus (6 ratings, all time) Buy
Price Targets & DCF
Current price
12.41
Low 20.00 +61.2%
Consensus 23.33 +88.0%
Median 24.00 +93.4%
High 26.00 +109.5%
Ratings Trend (MoM) 100% Bullish
Rating 2026-05 Change
Strong Buy 2 0
Buy 6 0
Hold 0 0
Sell 0 0
Strong Sell 0 0
Price Target Summary
Period # Analysts Avg Target
Last Month 1
24.00
+93.4%
Last Quarter 2
25.00
+101.5%
Last Year 4
21.50
+73.2%
All Time 5
19.00
+53.1%
Quality scores
Altman Z-Score
-4.70
Distress
Piotroski F-Score
4 / 9
Average
MOAT Score
0 / 10
No MOAT
Composite Rating
C
Overall Score
2 / 5
Medium
DCF Score
1 / 5
Low
ROE Score
5 / 5
High
ROA Score
1 / 5
Low
D/E Score
1 / 5
Low
P/E Score
1 / 5
Low
P/Book Score
1 / 5
Low
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
    +144.6% Q1'26: -84.8% (vs Q1'25)
  • EPS growth Biotechnology: +29.7%
    +33.0% Q1'26: -11.8% (vs Q1'25)
  • FCF margin FCF growth · Biotechnology: +16.2%
    -110.7% Q1'26: +5,393.2% (vs Q1'25)
  • EBIT margin Biotechnology: +0.0%
    -130.2% Q1'26: -13,930.7% (vs Q1'25)
  • ROIC Biotechnology: -16.1%
    -624.7% Q1'26: +387.5% (vs Q1'25)
  • Share dilution Biotechnology: -3.4%
    +15.2% Q1'26: +2.9% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    -0.84× Q1'26: -0.58× (vs Q1'25)
Valuation Multiples From To
Price Forecast (3Y) From To
Model
Adjust
P/E
Theoretical Return — If Invested Today

* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.

DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (1.24) × ERP
WACC = 90% × Ke + 10% × Kd (13.8%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Current price: 12.41
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2019
actual
Dec 2020
actual
Dec 2021
actual
Dec 2022
actual
Dec 2023
actual
Dec 2024
actual
Dec 2025
actual
Dec 2026
5 Rev. Ana.
5 EPS Ana.
Dec 2027
5 Rev. Ana.
5 EPS Ana.
Dec 2028
3 Rev. Ana.
3 EPS Ana.
Dec 2029
2 Rev. Ana.
1 EPS Ana.
Dec 2030
1 Rev. Ana.
1 EPS Ana.
Revenue
13.29M
est: 6.50M (+104.5%)
15.56M
est: 17.16M (-9.3%)
37.70M
est: 22.77M (+65.5%)
15.92M
est: 32.75M (-51.4%)
14.02M
est: 8.12M (+72.6%)
33.28M
est: 16.51M (+101.5%)
81.39M
est: 24.51M (+232.1%)
49.47M
365.5K – 183.50M
+101.9% YoY
97.33M
7.99M – 213.38M
+96.8% YoY
100.20M
6.46M – 257.34M
+2.9% YoY
265.59M
17.13M – 682.10M
+165.1% YoY
557.77M
35.98M – 1.43B
+110.0% YoY
EBITDA
-52.46M
est: -6.50M (-707.1%)
-53.68M
est: -17.16M (-212.9%)
-71.40M
est: -22.77M (-213.5%)
-116.07M
est: -32.75M (-254.4%)
-57.05M
est: -8.12M (-602.4%)
-121.69M
est: -16.51M (-636.9%)
-105.97M
est: -24.51M (-332.4%)
-49.47M
-183.50M – -365.5K
-101.9% YoY
-97.33M
-213.38M – -7.99M
-96.8% YoY
-100.20M
-257.34M – -6.46M
-2.9% YoY
-265.59M
-682.10M – -17.13M
-165.1% YoY
-557.77M
-1.43B – -35.98M
-110.0% YoY
EBIT
-54.70M
est: -6.50M (-741.5%)
-57.85M
est: -17.16M (-237.2%)
-79.27M
est: -22.77M (-248.1%)
-124.67M
est: -32.75M (-280.7%)
-70.78M
est: -8.12M (-771.5%)
-134.52M
est: -16.51M (-714.6%)
-105.97M
est: -24.51M (-332.4%)
-49.47M
-183.50M – -365.5K
-101.9% YoY
-97.33M
-213.38M – -7.99M
-96.8% YoY
-100.20M
-257.34M – -6.46M
-2.9% YoY
-265.59M
-682.10M – -17.13M
-165.1% YoY
-557.77M
-1.43B – -35.98M
-110.0% YoY
Net Income
-54.75M
est: -141.51M (+61.3%)
-57.99M
est: -110.42M (+47.5%)
-79.56M
est: -143.83M (+44.7%)
-129.62M
est: -124.54M (-4.1%)
-84.03M
est: -93.14M (+9.8%)
-147.79M
est: -157.51M (+6.2%)
-114.20M
est: -120.53M (+5.3%)
-171.95M
-206.89M – -51.51M
-42.7% YoY
-82.32M
-188.15M – 23.52M
+52.1% YoY
-139.12M
-173.29M – -104.95M
-69.0% YoY
-45.04M
-136.87M – 9.74M
+67.6% YoY
86.86M
-18.77M – 263.96M
+292.9% YoY
SGA
46.68M
est: 15.51M (+201.1%)
44.21M
est: 40.93M (+8.0%)
43.77M
est: 54.33M (-19.4%)
46.55M
est: 78.12M (-40.4%)
47.29M
est: 15.82M (+199.0%)
54.22M
est: 32.16M (+68.6%)
52.90M
est: 47.73M (+10.8%)
96.34M
711.8K – 357.38M
+101.9% YoY
189.56M
15.57M – 415.57M
+96.8% YoY
195.15M
12.59M – 501.19M
+2.9% YoY
517.25M
33.37M – 1.33B
+165.1% YoY
1.09B
70.08M – 2.79B
+110.0% YoY
EPS
-1.58
est: -2.03 (+22.0%)
-1.43
est: -1.58 (+9.6%)
-1.80
est: -2.06 (+12.6%)
-2.87
est: -2.69 (-6.8%)
-1.49
est: -1.49 (-0.1%)
-2.12
est: -1.95 (-8.7%)
-1.42
est: -1.70 (+16.3%)
-1.78
-2.57 – -0.64
-4.9% YoY
-1.59
-2.34 – 0.29
+10.7% YoY
-1.75
-2.15 – -1.30
-10.3% YoY
-0.56
-1.70 – 0.12
+68.1% YoY
1.08
-0.23 – 3.28
+292.9% YoY
Recent Grade Changes (3M)
Date Firm Previous New Grade Action
2026-04-22 Piper Sandler Overweight Overweight Maintain
2026-04-17 RBC Capital Outperform Outperform Maintain
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-11 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-05-08 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-05-07 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-05-06 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-05-05 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-05-04 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-05-01 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-04-30 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-04-29 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-04-28 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-04-27 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-04-24 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-04-23 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-04-22 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-04-21 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-04-20 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-04-17 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-04-16 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-04-15 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
138.17M
OE per share TTM
1.69
Owner's Yield
17.21%
Maintenance CapEx ratio
1,403.93%
Maint CapEx / Avg PPE
405.0%

Ownership Overview

Ownership breakdown
At a glance
Institutional holders
41
Total invested
122.46M
Insider transactions (90d)
2
Beneficial owners (>5%)
25
Beneficial owners (>5%)
# Reporting person Amount owned % of class Sole voting Shared voting Sole dispositive Shared dispositive Type Citizenship Filing date SEC filing
1 EIN: 22-1024240 6.64M 13.70% 6.64M 6.64M CO New Jersey 2022-11-14
2 Joseph Edelman 6.02M 18.10% 6.02M 10.00 IN United States of America 2019-03-05
3 Perceptive Advisors LLC 6.02M 18.10% 6.02M 10.00 IA Delaware 2019-03-05
4 Perceptive Life Sciences Master Fund, Ltd. 6.02M 18.10% 6.02M 10.00 CO Cayman Islands 2019-03-05
5 SANOFI 4.70M 7.40% 4.70M 4.70M CO The Republic of France 2023-11-06
6 W. Lawrence Hawkins 4.08M 6.90% 2.0K 4.08M 2.0K 4.08M HC, IN Delaware 2023-05-15
7 Prosight Management, LP 4.08M 6.90% 4.08M 4.08M IA Delaware 2023-05-15
8 Prosight Partners, LLC 4.08M 6.90% 4.08M 4.08M OO Delaware 2023-05-15
9 OrbiMed Capital LLC 3.59M 8.10% 3.59M 3.59M IA Delaware 2022-02-11
10 Kadmon Corporation, LLC 3.53M 12.90% 3.53M 3.53M CO Delaware 2019-02-08
11 Kadmon Holdings, Inc. 3.53M 12.90% 3.53M CO Delaware 2019-02-08
12 EIN:  22-1024240 2.90M 8.70% 2.90M CO New Jersey 2019-03-04
13 Adage Capital Advisors, L.L.C. 2.86M 6.44% 2.86M OO Delaware 2022-02-10
14 Adage Capital Partners GP, L.L.C. 2.86M 6.44% 2.86M OO Delaware 2022-02-10
15 Adage Capital Partners, L.P. 2.86M 6.44% 2.86M PN Delaware 2022-02-10
16 Phillip Gross 2.86M 6.44% 2.86M IN Delaware 2022-02-10
17 Robert Atchinson 2.86M 6.44% 2.86M IN Delaware 2022-02-10
18 Adena Estate Inc. 2.09M 5.70% 2.09M 2.09M CO NUMBER OF 2020-03-02
19 Inc. 1.98M 5.40% 1.98M 1.98M CO Maryland 2020-02-14
20 Alexandria Real Estate Equities, Inc. 1.98M 4.50% 1.98M CO Maryland 2022-02-11
21 Alexandria Venture Investments, LLC 1.98M 4.50% 1.98M OO Delaware 2022-02-11
22 Prosight Plus Fund, LP 1.05M 1.80% 1.05M 1.05M PN Delaware 2023-05-15
23 Prosight Fund, LP 401.4K 0.70% 401.4K 401.4K PN Delaware 2023-05-15
24 OrbiMed Advisors LLC 133.5K 0.30% 133.5K IA Delaware 2022-02-11
25 Advisors LLC 4.2K 0.01% 4.2K IA Delaware 2020-02-14

Institutional Activity (13F)

Institutional ownership trend From To
13F snapshot — 2026 Q1
Investors holding
41
-89 vs prev Q
New positions
5
Closed positions
93
Increased
21
Reduced
10
Put/Call ratio
0.00
Calls held
Puts held
Top institutional holders
# Investor Shares / Δ Mkt value / Δ Own% / Δ Weight% / Δ Avg px / Perf. Hold / Status
1 32.9K +32.9K (+100.0%) 261.91M +261.9M (+100.0%) 0.04% +0.041 pp 0.10% +0.103 pp USD7.95 +0.0% 1 qtrs NEW
2 SANOFI 12.20M +— (+0.0%) 96.97M -3.4M (-3.4%) 15.07% -0.068 pp 31.24% -7.318 pp USD6.09 +30.5% 5 qtrs
3 PERCEPTIVE ADVISORS LLC 10.33M -2.3M (-18.2%) 82.09M -21.7M (-20.9%) 12.76% -2.911 pp 1.46% -1.534 pp USD9.99 -20.4% 31 qtrs
4 JOHNSON & JOHNSON 6.64M +— (+0.0%) 52.80M -1.9M (-3.4%) 8.20% -0.037 pp 9.51% -1.278 pp USD9.43 -15.7% 18 qtrs
5 RUBRIC CAPITAL MANAGEMENT LP 6.18M +2.4M (+65.7%) 49.09M +18.4M (+60.1%) 7.63% +3.005 pp 0.59% +0.241 pp USD7.16 +11.0% 4 qtrs
6 ADAGE CAPITAL PARTNERS GP, L.L.C. 4.00M -184.6K (-4.4%) 31.80M -2.6M (-7.7%) 4.94% -0.251 pp 0.05% -0.006 pp USD11.75 -32.3% 28 qtrs
7 PROSIGHT MANAGEMENT, LP 3.21M -879.7K (-21.5%) 25.52M -8.1M (-24.2%) 3.97% -1.110 pp 5.27% -2.576 pp USD6.80 +16.9% 30 qtrs
8 MILLENNIUM MANAGEMENT LLC 3.18M +615.4K (+24.0%) 25.25M +4.2M (+19.8%) 3.92% +0.746 pp 0.01% +0.002 pp USD7.75 +2.6% 16 qtrs
9 BLACKROCK, INC. 3.07M +295.6K (+10.7%) 24.41M +1.6M (+6.9%) 3.79% +0.350 pp 0.00% +0.000 pp USD4.81 +65.3% 6 qtrs
10 683 CAPITAL MANAGEMENT, LLC 2.56M -65.9K (-2.5%) 20.34M -1.3M (-5.8%) 3.16% -0.096 pp 0.89% -0.244 pp USD10.90 -27.1% 30 qtrs
11 MORGAN STANLEY 1.83M +587.3K (+47.3%) 14.54M +4.3M (+42.3%) 2.26% +0.719 pp 0.00% +0.000 pp USD7.81 +1.8% 31 qtrs
12 KNOLL CAPITAL MANAGEMENT, LLC 1.25M +— (+0.0%) 9.94M -350.0K (-3.4%) 1.54% -0.007 pp 4.56% -0.955 pp USD4.17 +90.6% 6 qtrs
13 ERSTE ASSET MANAGEMENT GMBH 789.7K +80.0K (+11.3%) 6.28M +420.3K (+7.2%) 0.98% +0.095 pp 0.05% -0.004 pp USD10.24 -22.4% 17 qtrs
14 STATE STREET CORP 729.4K +48.4K (+7.1%) 5.80M +194.2K (+3.5%) 0.90% +0.056 pp 0.00% +0.000 pp USD14.45 -45.0% 29 qtrs
15 22NW, LP 586.5K +— (+0.0%) 4.66M -164.2K (-3.4%) 0.72% -0.003 pp 1.96% -0.312 pp USD6.52 +21.9% 3 qtrs
16 GEODE CAPITAL MANAGEMENT, LLC 573.8K +18.5K (+3.3%) 4.56M -8.7K (-0.2%) 0.71% +0.020 pp 0.00% +0.000 pp USD10.75 -26.0% 30 qtrs
17 LONG FOCUS CAPITAL MANAGEMENT, LLC 524.7K +— (+0.0%) 4.17M -146.9K (-3.4%) 0.65% -0.003 pp 0.11% -0.033 pp USD6.39 +24.4% 5 qtrs
18 VANGUARD GROUP INC 494.8K +30.8K (+6.6%) 3.93M +115.1K (+3.0%) 0.61% +0.036 pp 0.00% +0.000 pp USD11.01 -27.8% 29 qtrs
19 GOLDMAN SACHS GROUP INC 456.7K +196.5K (+75.5%) 3.63M +1.5M (+69.6%) 0.56% +0.241 pp 0.00% +0.000 pp USD7.48 +6.3% 28 qtrs
20 OPALEYE MANAGEMENT INC. 390.8K +390.8K (+100.0%) 3.11M +3.1M (+100.0%) 0.48% +0.483 pp 0.41% +0.410 pp USD7.95 +0.0% 1 qtrs NEW
21 D. E. SHAW & CO., INC. 381.8K +208.6K (+120.4%) 3.04M +1.6M (+112.9%) 0.47% +0.257 pp 0.00% +0.001 pp USD8.08 -1.6% 9 qtrs
22 J. GOLDMAN & CO LP 319.7K -1.5M (-82.2%) 2.54M -12.3M (-82.9%) 0.39% -1.840 pp 0.07% -0.306 pp USD6.03 +31.8% 8 qtrs
23 HENNION & WALSH ASSET MANAGEMENT, INC. 308.5K +199.5K (+183.1%) 2.45M +1.6M (+173.5%) 0.38% +0.246 pp 0.08% +0.052 pp USD7.69 +3.4% 3 qtrs
24 WOODLINE PARTNERS LP 300.3K +100.0K (+49.9%) 2.39M +738.9K (+44.8%) 0.37% +0.122 pp 0.01% +0.002 pp USD8.14 -2.3% 5 qtrs
25 JEFFERIES FINANCIAL GROUP INC. 298.2K +298.2K (+100.0%) 2.37M +2.4M (+100.0%) 0.37% +0.368 pp 0.01% +0.012 pp USD7.95 +0.0% 1 qtrs NEW
26 STEMPOINT CAPITAL LP 287.7K +205.8K (+251.4%) 2.29M +1.6M (+239.5%) 0.36% +0.254 pp 0.39% +0.257 pp USD8.03 -1.0% 2 qtrs
27 NORTHERN TRUST CORP 258.2K -12.7K (-4.7%) 2.05M -176.7K (-7.9%) 0.32% -0.017 pp 0.00% +0.000 pp USD12.23 -35.0% 30 qtrs
28 UBS GROUP AG 222.0K +140.4K (+172.1%) 1.77M +1.1M (+162.8%) 0.27% +0.173 pp 0.00% +0.000 pp USD7.46 +6.6% 31 qtrs
29 BANK OF AMERICA CORP /DE/ 208.5K +10.2K (+5.2%) 1.66M +26.0K (+1.6%) 0.26% +0.012 pp 0.00% +0.000 pp USD6.50 +22.3% 31 qtrs
30 PRIVIUM FUND MANAGEMENT B.V. 200.0K +37.0K (+22.7%) 1.59M +248.5K (+18.5%) 0.25% +0.045 pp 0.29% +0.052 pp USD5.96 +33.4% 8 qtrs
31 ROYCE & ASSOCIATES LP 176.1K +176.1K (+100.0%) 1.40M +1.4M (+100.0%) 0.22% +0.218 pp 0.01% +0.014 pp USD7.95 +0.0% 22 qtrs
32 CITADEL ADVISORS LLC 143.4K -61.4K (-30.0%) 1.14M -545.7K (-32.4%) 0.18% -0.077 pp 0.00% 0.000 pp USD6.33 +25.6% 26 qtrs
33 NUVEEN, LLC 131.1K +— (+0.0%) 1.04M -36.7K (-3.4%) 0.16% -0.001 pp 0.00% +0.000 pp USD6.78 +17.3% 4 qtrs
34 WELLINGTON MANAGEMENT GROUP LLP 130.6K -11.1K (-7.8%) 1.04M -128.1K (-11.0%) 0.16% -0.015 pp 0.00% +0.000 pp USD6.68 +19.0% 9 qtrs
35 BNP PARIBAS ARBITRAGE, SNC 128.0K +119.1K (+1,332.2%) 1.02M +944.0K (+1,283.5%) 0.16% +0.147 pp 0.00% +0.000 pp USD7.88 +0.9% 29 qtrs
36 BLAIR WILLIAM & CO/IL 125.4K -7.1K (-5.4%) 996.9K -93.8K (-8.6%) 0.15% -0.010 pp 0.00% 0.000 pp USD23.69 -66.4% 17 qtrs
37 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 111.4K +7.4K (+7.1%) 885.8K +29.4K (+3.4%) 0.14% +0.009 pp 0.00% +0.000 pp USD11.96 -33.5% 28 qtrs
38 AQR CAPITAL MANAGEMENT LLC 108.0K +230.0 (+0.2%) 858.7K -28.4K (-3.2%) 0.13% 0.000 pp 0.00% 0.000 pp USD6.74 +18.0% 4 qtrs
39 BANK OF NEW YORK MELLON CORP 101.1K -4.7K (-4.5%) 803.7K -67.1K (-7.7%) 0.12% -0.006 pp 0.00% +0.000 pp USD12.48 -36.3% 28 qtrs
40 JANE STREET GROUP, LLC 98.2K -6.3K (-6.0%) 781.0K -79.0K (-9.2%) 0.12% -0.008 pp 0.00% +0.000 pp USD8.23 -3.4% 2 qtrs
41 BARCLAYS PLC 95.7K -52.1K (-35.2%) 761.1K +144.6K (+23.5%) 0.12% -0.065 pp 0.00% +0.000 pp USD7.15 +11.2% 30 qtrs
42 RUSSELL INVESTMENTS GROUP, LTD. 95.7K +12.9K (+15.5%) 761.0K +79.2K (+11.6%) 0.12% +0.015 pp 0.00% +0.000 pp USD6.04 +31.6% 17 qtrs
43 PLATINUM INVESTMENT MANAGEMENT LTD 93.9K -33.6K (-26.4%) 746.7K -302.9K (-28.9%) 0.12% -0.042 pp 0.17% +0.105 pp USD4.17 +90.6% 6 qtrs
44 INVESCO LTD. 90.9K +21.4K (+30.8%) 722.5K +150.5K (+26.3%) 0.11% +0.026 pp 0.00% +0.000 pp USD7.45 +6.7% 19 qtrs
45 EXODUSPOINT CAPITAL MANAGEMENT, LP 86.9K +44.0K (+102.3%) 691.1K +337.4K (+95.4%) 0.11% +0.054 pp 0.01% +0.002 pp USD8.09 -1.7% 2 qtrs
46 SUSQUEHANNA INTERNATIONAL GROUP, LLP 76.9K +38.3K (+99.1%) 611.4K +293.5K (+92.3%) 0.10% +0.047 pp 0.00% +0.000 pp USD7.01 +13.4% 6 qtrs
47 KENNEDY CAPITAL MANAGEMENT LLC 70.7K +1.5K (+2.2%) 562.4K -7.5K (-1.3%) 0.09% +0.002 pp 0.01% -0.001 pp USD6.81 +16.7% 8 qtrs
48 DAVENPORT & CO LLC 69.2K +14.0K (+25.4%) 550.1K +95.8K (+21.1%) 0.09% +0.017 pp 0.00% +0.001 pp USD10.68 -25.6% 17 qtrs
49 TREXQUANT INVESTMENT LP 67.5K +67.5K (+100.0%) 536.9K +536.9K (+100.0%) 0.08% +0.083 pp 0.00% +0.005 pp USD7.95 +0.0% 1 qtrs NEW
50 TOCQUEVILLE ASSET MANAGEMENT L.P. 66.4K +7.2K (+12.2%) 527.9K +40.7K (+8.3%) 0.08% +0.009 pp 0.01% +0.001 pp USD10.72 -25.8% 17 qtrs
51 FORT SHERIDAN ADVISORS LLC 65.6K -64.0 (-0.1%) 521.3K -18.9K (-3.5%) 0.08% 0.000 pp 0.07% -0.004 pp USD14.16 -43.9% 28 qtrs
52 Y-INTERCEPT (HONG KONG) LTD 65.6K +65.6K (+100.0%) 521.2K +521.2K (+100.0%) 0.08% +0.081 pp 0.01% +0.012 pp USD7.95 +0.0% 1 qtrs NEW
53 QUANTINNO CAPITAL MANAGEMENT LP 60.8K +3.5K (+6.2%) 483.0K +12.0K (+2.5%) 0.08% +0.004 pp 0.00% 0.000 pp USD6.84 +16.2% 3 qtrs
54 RAYMOND JAMES FINANCIAL INC 57.2K +57.2K (+100.0%) 455.0K +455.0K (+100.0%) 0.07% +0.071 pp 0.00% +0.000 pp USD7.95 +0.0% 3 qtrs
55 JACOBS LEVY EQUITY MANAGEMENT, INC 56.2K +56.2K (+100.0%) 447.1K +447.1K (+100.0%) 0.07% +0.070 pp 0.00% +0.002 pp USD7.95 +0.0% 1 qtrs NEW
56 RHUMBLINE ADVISERS 56.2K -4.5K (-7.4%) 446.8K -52.5K (-10.5%) 0.07% -0.006 pp 0.00% +0.000 pp USD11.40 -30.3% 28 qtrs
57 ALLIANCEBERNSTEIN L.P. 54.6K +— (+0.0%) 434.0K -15.3K (-3.4%) 0.07% 0.000 pp 0.00% +0.000 pp USD13.22 -39.9% 27 qtrs
58 BROWN ADVISORY INC 50.0K +— (+0.0%) 397.5K -14.0K (-3.4%) 0.06% 0.000 pp 0.00% +0.000 pp USD6.52 +21.9% 3 qtrs
59 WELLS FARGO & COMPANY/MN 49.8K +22.5K (+82.3%) 395.8K +171.1K (+76.1%) 0.06% +0.028 pp 0.00% +0.000 pp USD6.99 +13.7% 12 qtrs
60 STATE OF WISCONSIN INVESTMENT BOARD 42.6K +— (+0.0%) 339.0K -11.9K (-3.4%) 0.05% 0.000 pp 0.00% +0.000 pp USD8.02 -0.9% 27 qtrs
61 DEUTSCHE BANK AG\ 40.7K +7.4K (+22.2%) 323.7K +49.4K (+18.0%) 0.05% +0.009 pp 0.00% +0.000 pp USD9.18 -13.4% 30 qtrs
62 XTX TOPCO LTD 38.0K +3.8K (+11.0%) 302.3K +20.3K (+7.2%) 0.05% +0.005 pp 0.01% -0.007 pp USD8.20 -3.0% 2 qtrs
63 JUMP FINANCIAL, LLC 37.0K -33.6K (-47.6%) 294.2K -286.9K (-49.4%) 0.05% -0.042 pp 0.00% -0.003 pp USD8.23 -3.4% 4 qtrs
64 LETKO, BROSSEAU & ASSOCIATES INC 32.0K +— (+0.0%) 254.4K -9.0K (-3.4%) 0.04% 0.000 pp 0.00% 0.000 pp USD5.15 +54.4% 10 qtrs
65 VIRTUS INVESTMENT ADVISERS, INC. 29.8K +29.8K (+100.0%) 237.1K +237.1K (+100.0%) 0.04% +0.037 pp 0.06% +0.064 pp USD7.95 +0.0% 1 qtrs NEW
66 ALPHACENTRIC ADVISORS LLC 28.5K +28.5K (+100.0%) 226.5K +226.5K (+100.0%) 0.04% +0.035 pp 0.23% +0.226 pp USD7.95 +0.0% 1 qtrs NEW
67 ENGINEERS GATE MANAGER LP 26.8K +26.8K (+100.0%) 213.4K +213.4K (+100.0%) 0.03% +0.033 pp 0.00% +0.003 pp USD7.95 +0.0% 1 qtrs NEW
68 CREATIVEONE WEALTH, LLC 26.4K -5.2K (-16.3%) 210.1K -49.8K (-19.2%) 0.03% -0.007 pp 0.01% -0.001 pp USD5.17 +53.8% 12 qtrs
69 SKYVIEW INVESTMENT ADVISORS, LLC 24.0K +— (+0.0%) 191.0K -7.0K (-3.5%) 0.03% 0.000 pp 0.02% -0.001 pp USD4.10 +93.9% 7 qtrs
70 JPMORGAN CHASE & CO 23.9K -36.4K (-60.4%) 190.4K -306.7K (-61.7%) 0.03% -0.045 pp 0.00% +0.000 pp USD7.68 +3.5% 30 qtrs
71 HSBC HOLDINGS PLC 23.8K +4.6K (+24.3%) 188.7K +30.6K (+19.3%) 0.03% +0.006 pp 0.00% +0.000 pp USD6.49 +22.5% 8 qtrs
72 PRICE T ROWE ASSOCIATES INC /MD/ 22.8K +— (+0.0%) 182.0K -6.0K (-3.2%) 0.03% 0.000 pp 0.00% +0.000 pp USD5.11 +55.6% 7 qtrs
73 FOX RUN MANAGEMENT, L.L.C. 22.5K -479.0 (-2.1%) 178.8K -10.2K (-5.4%) 0.03% -0.001 pp 0.03% -0.002 pp USD8.23 -3.4% 2 qtrs
74 SG AMERICAS SECURITIES, LLC 22.4K -7.6K (-25.5%) 178.0K -69.0K (-27.9%) 0.03% -0.010 pp 0.00% -0.001 pp USD8.23 -3.4% 6 qtrs
75 MITSUBISHI UFJ KOKUSAI ASSET MANAGEMENT CO., LTD. 22.6K +22.6K (+100.0%) 176.3K +176.3K (+100.0%) 0.03% +0.028 pp 0.00% +0.000 pp USD7.95 +0.0% 1 qtrs NEW
76 MIRAE ASSET GLOBAL ETFS HOLDINGS LTD. 21.0K +2.0K (+10.3%) 167.0K +10.3K (+6.6%) 0.03% +0.002 pp 0.00% +0.000 pp USD4.90 +62.2% 7 qtrs
77 BEACON POINTE ADVISORS, LLC 20.8K +— (+0.0%) 165.1K -5.8K (-3.4%) 0.03% 0.000 pp 0.00% 0.000 pp USD8.23 -3.4% 2 qtrs
78 METLIFE INVESTMENT MANAGEMENT, LLC 20.0K -4.2K (-17.2%) 159.3K -39.9K (-20.0%) 0.02% -0.005 pp 0.00% 0.000 pp USD7.30 +8.9% 28 qtrs
79 VOLEON CAPITAL MANAGEMENT LP 16.6K +16.6K (+100.0%) 131.9K +131.9K (+100.0%) 0.02% +0.021 pp 0.00% +0.003 pp USD7.95 +0.0% 1 qtrs NEW
80 INTECH INVESTMENT MANAGEMENT LLC 16.0K +— (+0.0%) 127.3K -4.5K (-3.4%) 0.02% 0.000 pp 0.00% +0.000 pp USD6.43 +23.6% 5 qtrs
81 CITIGROUP INC 15.6K +2.1K (+15.9%) 123.6K +13.2K (+12.0%) 0.02% +0.003 pp 0.00% +0.000 pp USD6.04 +31.6% 30 qtrs
82 CREATIVE PLANNING 15.4K -1.1K (-6.9%) 122.8K -13.7K (-10.0%) 0.02% -0.002 pp 0.00% +0.000 pp USD7.11 +11.8% 4 qtrs
83 PERIGON WEALTH MANAGEMENT, LLC 15.0K +15.0K (+100.0%) 119.3K +119.3K (+100.0%) 0.02% +0.019 pp 0.00% +0.002 pp USD7.95 +0.0% 1 qtrs NEW
84 CIBC PRIVATE WEALTH GROUP, LLC 15.0K +— (+0.0%) 119.3K -4.2K (-3.4%) 0.02% 0.000 pp 0.00% +0.000 pp USD4.91 +61.9% 10 qtrs
85 MANUFACTURERS LIFE INSURANCE COMPANY, THE 14.9K -577.0 (-3.7%) 118.4K -8.9K (-7.0%) 0.02% -0.001 pp 0.00% +0.000 pp USD12.78 -37.8% 27 qtrs
86 FMR LLC 13.8K +8.3K (+150.3%) 109.9K +64.4K (+141.8%) 0.02% +0.010 pp 0.00% +0.000 pp USD7.16 +11.0% 16 qtrs
87 CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD. 13.1K -985.0 (-7.0%) 104.3K -11.8K (-10.1%) 0.02% -0.001 pp 0.01% -0.002 pp USD5.42 +46.7% 14 qtrs
88 ABEL HALL, LLC 12.3K +12.3K (+100.0%) 97.7K +97.7K (+100.0%) 0.02% +0.015 pp 0.02% +0.023 pp USD7.95 +0.0% 1 qtrs NEW
89 STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 12.2K +— (+0.0%) 97.3K -3.4K (-3.4%) 0.02% 0.000 pp 0.00% +0.000 pp USD15.30 -48.0% 19 qtrs
90 HOBBS GROUP ADVISORS, LLC 12.0K -2.3K (-15.9%) 95.0K -21.9K (-18.8%) 0.01% -0.003 pp 0.03% -0.008 pp USD6.52 +21.9% 3 qtrs
91 PROSHARE ADVISORS LLC 11.8K +11.8K (+100.0%) 93.7K +93.7K (+100.0%) 0.01% +0.015 pp 0.00% +0.000 pp USD7.95 +0.0% 8 qtrs
92 POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY 11.7K +— (+0.0%) 92.7K -3.3K (-3.4%) 0.01% 0.000 pp 0.00% +0.000 pp USD6.09 +30.5% 5 qtrs
93 ROYAL BANK OF CANADA 10.9K -289.5K (-96.4%) 87.0K -2.4M (-96.5%) 0.01% -0.359 pp 0.00% 0.000 pp USD6.50 +22.3% 27 qtrs
94 LEVIN CAPITAL STRATEGIES, L.P. 10.0K -15.0K (-60.0%) 79.5K -126.3K (-61.4%) 0.01% -0.019 pp 0.01% -0.012 pp USD6.52 +21.9% 3 qtrs
95 CWM, LLC 7.8K -67.0 (-0.9%) 62.0K -3.0K (-4.6%) 0.01% 0.000 pp 0.00% +0.000 pp USD6.70 +18.7% 6 qtrs
96 NEW YORK STATE COMMON RETIREMENT FUND 7.3K +— (+0.0%) 57.7K -2.0K (-3.4%) 0.01% +0.000 pp 0.00% +0.000 pp USD21.57 -63.1% 29 qtrs
97 ROCKEFELLER CAPITAL MANAGEMENT L.P. 6.1K +630.0 (+11.5%) 48.7K +3.5K (+7.7%) 0.01% +0.001 pp 0.00% +0.000 pp USD8.20 -3.0% 2 qtrs
98 LEGAL & GENERAL GROUP PLC 4.3K -139.0 (-3.1%) 34.0K -2.3K (-6.4%) 0.01% 0.000 pp 0.00% +0.000 pp USD10.65 -25.4% 30 qtrs
99 STATE OF ALASKA, DEPARTMENT OF REVENUE 4.0K +— (+0.0%) 32.0K -1.0K (-3.0%) 0.01% +0.000 pp 0.00% +0.000 pp USD8.23 -3.4% 2 qtrs
Ownership breakdown by holder

Insider Activity

Insider Activity — Latest Quarter
Ratio by transactions
0.50
Neutral
Ratio by volume
3.00
Bullish
Buys
1
Sells
2
Shares acquired
555.6K
Shares disposed
83.7K
Cash buys
Cash sales
2.00
Net activity
+471,894
Insider buys vs sells (history) From To
Recent insider transactions From To
Date Person Role Transaction A/D Security Shares Price Value Owned after D/I Filing
2026-04-21 Giroux Richard Officer S-Sale D Ordinary Shares 56,000 10.22 572.3K 971,530 D
2026-04-17 PERCEPTIVE ADVISORS LLC Director / 10% Owner A-Award A Ordinary Shares 555,555 9.00 5.00M 10,786,658 I
2026-04-07 Naylor Stuart Officer S-Sale D Ordinary Shares 27,661 9.36 258.9K 668,505 D
2026-03-25 PERCEPTIVE ADVISORS LLC Director / 10% Owner A-Award A Warrant (Right to Buy) 400,000 8.00 3.20M 400,000 I
2026-03-24 Forbes Alexandria Director / Officer S-Sale D Ordinary Shares 62,000 7.41 459.4K 1,449,695 D
2026-02-21 Zeldin Robert K Officer M-Exempt D Restricted Share Units 7,500 0.00 7,500 D
2026-02-21 Wollin Robert J Officer M-Exempt D Restricted Share Units 11,250 0.00 11,250 D
2026-02-21 Naylor Stuart Officer F-InKind D Ordinary Shares 11,750 7.45 87.5K 696,166 D
2026-02-21 Giroux Richard Officer M-Exempt D Restricted Share Units 60,000 0.00 60,000 D
2026-02-21 Forbes Alexandria Director / Officer M-Exempt A Ordinary Shares 62,500 0.00 1,544,743 D
2026-01-17 Zeldin Robert K Officer M-Exempt D Restricted Share Units 35,000 0.00 35,000 D
2026-01-17 Wollin Robert J Officer M-Exempt D Restricted Share Units 50,000 0.00 50,000 D
2026-01-17 Naylor Stuart Officer F-InKind D Ordinary Shares 35,250 7.42 261.6K 682,916 D
2026-01-17 Giroux Richard Officer M-Exempt D Restricted Share Units 310,000 0.00 310,000 D
2026-01-17 Forbes Alexandria Director / Officer M-Exempt D Restricted Share Units 310,000 0.00 310,000 D
2026-01-07 Zeldin Robert K Officer F-InKind D Ordinary Shares 7,814 7.73 60.4K 146,204 D
2026-01-07 Wollin Robert J Officer M-Exempt D Restricted Share Units 7,500 0.00 0 D
2026-01-07 Naylor Stuart Officer M-Exempt A Ordinary Shares 37,500 0.00 660,791 D
2026-01-07 Giroux Richard Officer M-Exempt D Restricted Share Units 52,500 0.00 0 D
2026-01-07 Forbes Alexandria Director / Officer M-Exempt A Ordinary Shares 62,500 0.00 1,370,233 D
2025-12-31 PERCEPTIVE ADVISORS LLC Director / 10% Owner D-Return D Ordinary Shares 2,300,000 7.91 18.19M 10,231,103 I
2025-12-23 Forbes Alexandria Director / Officer G-Gift D Ordinary Shares 6,250 0.00 1,307,733 D
2025-11-20 Wollin Robert J Officer G-Gift D Ordinary Shares 5,000 0.00 26,146 D
2025-10-21 Giroux Richard Officer S-Sale D Ordinary Shares 24,000 8.87 212.9K 829,494 D
2025-10-07 Forbes Alexandria Director / Officer S-Sale D Ordinary Shares 47,500 8.39 398.5K 1,313,983 D
2025-07-22 Giroux Richard Officer S-Sale D Ordinary Shares 24,000 8.52 204.5K 853,494 D
2025-07-08 Forbes Alexandria Director / Officer S-Sale D Ordinary Shares 47,500 7.97 378.6K 1,361,483 D
2025-06-30 Giroux Richard Officer G-Gift D Ordinary Shares 5,000 0.00 877,494 D
2025-06-12 Yu Debra Director A-Award A Restricted Share Units 45,000 0.00 45,000 D
2025-06-12 Seligman Nicole Director A-Award A Restricted Share Units 45,000 0.00 45,000 D
2025-06-12 SHENK THOMAS E Director A-Award A Restricted Share Units 45,000 0.00 45,000 D
2025-06-12 PERCEPTIVE ADVISORS LLC Director / 10% Owner A-Award A Restricted Share Units 45,000 0.00 45,000 I
2025-06-12 Mendoza Neil Director A-Award A Restricted Share Units 45,000 0.00 45,000 D
2025-06-12 Hukkelhoven Ellen Director A-Award A Restricted Share Units 45,000 0.00 45,000 D
2025-06-12 Harris Keith R. Director A-Award A Restricted Share Units 75,000 0.00 75,000 D
2025-06-06 Harris Keith R. Director M-Exempt D Restricted Share Units 75,000 0.00 0 D
2025-04-22 Giroux Richard Officer S-Sale D Ordinary Shares 24,000 6.00 144.0K 882,494 D
2025-04-08 Forbes Alexandria Director / Officer S-Sale D Ordinary Shares 47,500 5.34 253.7K 1,408,983 D
2025-04-03 Zeldin Robert K Officer A-Award A Restricted Share Units 90,000 0.00 90,000 D
2025-04-03 Wollin Robert J Officer A-Award A Restricted Share Units 100,000 0.00 100,000 D
2025-04-03 Naylor Stuart Officer A-Award A Restricted Share Units 100,000 0.00 100,000 D
2025-04-03 Giroux Richard Officer A-Award A Restricted Share Units 950,000 0.00 950,000 D
2025-04-03 Forbes Alexandria Director / Officer A-Award A Restricted Share Units 950,000 0.00 950,000 D
2025-02-21 Zeldin Robert K Officer M-Exempt D Restricted Share Units 15,000 0.00 15,000 D
2025-02-21 Wollin Robert J Officer M-Exempt D Restricted Share Units 22,500 0.00 22,500 D
2025-02-21 Naylor Stuart Officer F-InKind D Ordinary Shares 23,500 7.30 171.6K 623,291 D
2025-02-21 Giroux Richard Officer M-Exempt D Restricted Share Units 120,000 0.00 120,000 D
2025-02-21 Forbes Alexandria Director / Officer M-Exempt D Restricted Share Units 125,000 0.00 125,000 D
2025-01-21 Giroux Richard Officer S-Sale D Ordinary Shares 24,000 6.29 151.0K 849,947 D
2025-01-14 Zeldin Robert K Officer M-Exempt D Restricted Share Units 37,500 0.00 0 D
2025-01-14 Wollin Robert J Officer M-Exempt D Restricted Share Units 5,000 0.00 0 D
2025-01-14 Naylor Stuart Officer M-Exempt A Ordinary Shares 23,750 0.00 607,954 D
2025-01-14 Giroux Richard Officer M-Exempt D Restricted Share Units 25,000 0.00 0 D
2025-01-14 Forbes Alexandria Director / Officer M-Exempt A Ordinary Shares 30,000 0.00 1,413,441 D
2025-01-08 Forbes Alexandria Director / Officer S-Sale D Ordinary Shares 11,661 6.30 73.5K 1,383,441 D
2025-01-07 Zeldin Robert K Officer M-Exempt A Ordinary Shares 17,500 0.00 111,958 D
2025-01-07 Wollin Robert J Officer M-Exempt D Restricted Share Units 7,500 0.00 7,500 D
2025-01-07 Naylor Stuart Officer M-Exempt D Restricted Share Units 37,500 0.00 37,500 D
2025-01-07 Giroux Richard Officer M-Exempt D Restricted Share Units 52,500 0.00 52,500 D
2025-01-07 Forbes Alexandria Director / Officer M-Exempt D Restricted Share Units 62,500 0.00 62,500 D
2024-08-12 Sanofi 10% Owner I Ordinary Shares ($0.00003881 par value per share) 0 0.00 11,500,000
2024-08-12 PERCEPTIVE ADVISORS LLC Director / 10% Owner P-Purchase A Ordinary Shares 1,250,000 4.00 5.00M 12,531,103
2024-06-06 Yu Debra Director A-Award A Restricted Share Units 45,000 0.00 45,000
2024-06-06 Seligman Nicole Director A-Award A Restricted Share Units 45,000 0.00 45,000
2024-06-06 SHENK THOMAS E Director A-Award A Restricted Share Units 45,000 0.00 45,000
2024-06-06 PERCEPTIVE ADVISORS LLC Director / 10% Owner A-Award A Restricted Share Units 45,000 0.00 45,000
2024-06-06 Mendoza Neil Director A-Award A Restricted Share Units 45,000 0.00 45,000
2024-06-06 Indyk Martin Director A-Award A Restricted Share Units 45,000 0.00 45,000
2024-06-06 Hukkelhoven Ellen Director A-Award A Restricted Share Units 45,000 0.00 45,000
2024-06-06 Harris Keith R. Director A-Award A Restricted Share Units 75,000 0.00 75,000
2024-06-05 Indyk Martin Director M-Exempt A Ordinary Shares 20,000 0.00 35,000
2024-06-05 Harris Keith R. Director M-Exempt A Ordinary Shares 30,000 0.00 50,000
2024-05-28 Giroux Richard Officer G-Gift D Ordinary Shares 3,000 0.00 837,426
2024-04-05 Forbes Alexandria Director / Officer G-Gift D Ordinary Shares 1,000 0.00 1,372,504
2024-03-12 Forbes Alexandria Director / Officer G-Gift D Ordinary Shares 2,000 0.00 1,373,504
2024-02-29 Giroux Richard Officer G-Gift D Ordinary Shares 13,500 0.00 840,426
2024-01-17 Zeldin Robert K Officer A-Award A Restricted Share Units 70,000 0.00 70,000
2024-01-17 Wollin Robert J Officer A-Award A Restricted Share Units 100,000 0.00 100,000
2024-01-17 Naylor Stuart Officer A-Award A Restricted Share Units 150,000 0.00 150,000
2024-01-17 Giroux Richard Officer A-Award A Restricted Share Units 620,000 0.00 620,000
2024-01-17 Forbes Alexandria Director / Officer A-Award A Restricted Share Units 620,000 0.00 620,000
2024-01-14 Zeldin Robert K Officer M-Exempt A Ordinary Shares 37,500 0.00 104,480
2024-01-14 Wollin Robert J Officer M-Exempt D Restricted Share Units 5,000 0.00 5,000
2024-01-14 Naylor Stuart Officer M-Exempt D Restricted Share Units 23,750 0.00 23,750
2024-01-14 Giroux Richard Officer M-Exempt D Restricted Share Units 25,000 0.00 25,000
2024-01-14 Forbes Alexandria Director / Officer M-Exempt D Restricted Share Units 30,000 0.00 30,000
2024-01-08 Naylor Stuart Officer F-InKind D Ordinary Shares 18,800 6.63 124.6K 551,742
2024-01-08 Giroux Richard Officer F-InKind D Ordinary Shares 19,829 6.63 131.5K 842,145
2024-01-08 Forbes Alexandria Director / Officer M-Exempt D Restricted Share Units 48,750 0.00 0
2024-01-07 Zeldin Robert K Officer M-Exempt D Restricted Share Units 35,000 0.00 35,000
2024-01-07 Wollin Robert J Officer M-Exempt D Restricted Share Units 15,000 0.00 15,000
2024-01-07 Naylor Stuart Officer F-InKind D Ordinary Shares 35,250 6.30 222.1K 530,542
2024-01-07 Giroux Richard Officer M-Exempt D Restricted Share Units 105,000 0.00 105,000
2024-01-07 Forbes Alexandria Director / Officer M-Exempt A Ordinary Shares 125,000 0.00 1,404,489
2023-09-15 Johnson & Johnson Innovation - JJDC, Inc. 10% Owner D Ordinary Shares 0 0.00 6,641,064
2023-06-08 Yu Debra Director A-Award A Stock Option (right to buy) 20,000 8.04 160.8K 20,000
2023-06-08 Seligman Nicole Director A-Award A Restricted Share Units 22,500 0.00 22,500
2023-06-08 SHENK THOMAS E Director A-Award A Restricted Share Units 20,000 0.00 20,000
2023-06-08 PERCEPTIVE ADVISORS LLC Director / 10% Owner A-Award A Stock Option (right to buy) 20,000 8.04 160.8K 20,000
2023-06-08 Mendoza Neil Director A-Award A Stock Option (right to buy) 20,000 8.04 160.8K 20,000
2023-06-08 Indyk Martin Director A-Award A Restricted Share Units 20,000 0.00 20,000
2023-06-08 Hukkelhoven Ellen Director A-Award A Stock Option (right to buy) 20,000 8.04 160.8K 20,000
2023-06-08 Harris Keith R. Director A-Award A Restricted Share Units 30,000 0.00 30,000
2023-06-07 Indyk Martin Director M-Exempt A Ordinary Shares 15,000 0.00 15,000
2023-06-07 Harris Keith R. Director M-Exempt A Ordinary Shares 20,000 0.00 20,000
2023-05-05 PERCEPTIVE ADVISORS LLC Director / 10% Owner P-Purchase A Ordinary Shares 4,347,826 5.75 25.00M 11,281,103
2023-02-21 Zeldin Robert K Officer A-Award A Stock Option (Right to Buy) 30,000 8.60 258.0K 30,000
2023-02-21 Wollin Robert J Officer A-Award A Stock Option (Right to Buy) 45,000 8.60 387.0K 45,000
2023-02-21 Naylor Stuart Officer A-Award A Restricted Share Units 100,000 0.00 100,000
2023-02-21 Giroux Richard Officer A-Award A Stock Option (Right to Buy) 135,000 8.60 1.16M 135,000
2023-02-21 Forbes Alexandria Director / Officer A-Award A Stock Option (Right to Buy) 225,000 8.60 1.94M 225,000
2023-01-14 Zeldin Robert K Director / Officer M-Exempt A Ordinary Shares 75,000 0.00 80,000
2023-01-14 Wollin Robert J Director M-Exempt A Ordinary Shares 10,000 0.00 11,000
2023-01-14 Naylor Stuart Director / Officer M-Exempt A Ordinary Shares 47,500 0.00 513,117
2023-01-14 Giroux Richard Director F-InKind D Ordinary Shares 26,438 6.99 184.8K 774,994
2023-01-14 Forbes Alexandria Director M-Exempt A Ordinary Shares 60,000 0.00 1,138,176
2023-01-08 Naylor Stuart Director / Officer M-Exempt D Restricted Share Units 40,000 0.00 40,000
2023-01-08 Giroux Richard Director F-InKind D Ordinary Shares 19,829 6.60 130.9K 751,432
2023-01-08 Forbes Alexandria Director M-Exempt D Restricted Share Units 48,750 0.00 48,750
2022-12-31 Forbes Alexandria Director / Officer I Ordinary Shares 0 0.00 175,000
2022-11-09 JOHNSON & JOHNSON Director I Ordinary Shares 0 0.00 6,641,064
2022-08-02 PERCEPTIVE ADVISORS LLC Director / 10% Owner A-Award A Warrant (Right to Buy) 400,000 15.00 6.00M 400,000 I
2022-06-07 Seligman Nicole Director A-Award A Stock Option (right to buy) 15,000 0.00 15,000
2022-06-07 SHENK THOMAS E Director A-Award A Stock Option (right to buy) 15,000 8.25 123.8K 15,000
2022-06-07 PERCEPTIVE ADVISORS LLC Director / 10% Owner A-Award A Restricted Share Units 15,000 0.00 15,000
2022-06-07 Mendoza Neil Director A-Award A Stock Option (right to buy) 15,000 0.00 15,000
2022-06-07 MARCUS JOEL S Director A-Award A Stock Option (right to buy) 15,000 0.00 15,000
2022-06-07 LEVINE ARNOLD J Director A-Award A Stock Option (right to buy) 15,000 0.00 15,000
2022-06-07 Indyk Martin Director A-Award A Stock Option (right to buy) 15,000 8.25 123.8K 15,000
2022-06-07 Hukkelhoven Ellen Director A-Award A Stock Option (right to buy) 15,000 0.00 15,000
2022-06-07 Harris Keith R. Director A-Award A Stock Option (right to buy) 20,000 8.25 165.0K 20,000
2022-06-07 EDELMAN JOSEPH Director A-Award A Restricted Share Units 15,000 0.00 15,000
2022-06-03 Zeldin Robert K Director / Officer P-Purchase A Ordinary Shares 6 7.89 47.34 5,000
2022-05-25 Wollin Robert J Director P-Purchase A Ordinary Shares 1,000 7.94 7.9K 1,000
2022-04-25 Yu Debra 0 0.00 0
2022-01-08 Naylor Stuart Officer M-Exempt D Restricted Share Units 80,000 0.00 80,000
2022-01-08 Giroux Richard Officer M-Exempt D Restricted Share Units 75,000 0.00 75,000
2022-01-08 Forbes Alexandria Director / Officer M-Exempt D Restricted Share Units 97,500 0.00 97,500
2022-01-07 Zeldin Robert K Officer A-Award A Stock Option (Right to Buy) 30,000 21.53 645.9K 30,000
2022-01-07 Wollin Robert J Officer A-Award A Stock Option (Right to Buy) 30,000 21.53 645.9K 30,000
2022-01-07 Naylor Stuart Officer A-Award A Restricted Share Units 150,000 0.00 150,000
2022-01-07 Giroux Richard Officer A-Award A Restricted Share Units 210,000 0.00 210,000
2022-01-07 Forbes Alexandria Director / Officer A-Award A Restricted Share Units 250,000 0.00 250,000
2021-12-31 Giroux Richard Officer I Ordinary Shares 0 0.00 5,152
2021-12-31 Forbes Alexandria Director / Officer I Ordinary Shares 0 0.00 150,000
2021-11-17 Forbes Alexandria Director / Officer S-Sale D Ordinary Shares 15,000 19.86 297.9K 1,080,781
2021-11-16 Forbes Alexandria Director / Officer S-Sale D Ordinary Shares 11,800 19.82 233.9K 1,098,981
2021-10-20 Giroux Richard Officer S-Sale D Ordinary Shares 13,744 20.93 287.7K 826,174
2021-10-19 Giroux Richard Officer S-Sale D Ordinary Shares 1,300 20.07 26.1K 839,918
2021-10-18 Naylor Stuart Officer S-Sale D Ordinary Shares 12,000 17.95 215.4K 402,017
2021-10-18 Forbes Alexandria Director / Officer S-Sale D Ordinary Shares 23,821 17.21 410.0K 1,116,960
2021-07-20 Naylor Stuart Officer S-Sale D Ordinary Shares 9,390 15.06 141.4K 414,017
2021-07-13 Naylor Stuart Officer S-Sale D Ordinary Shares 2,610 15.04 39.3K 423,407
2021-06-10 Seligman Nicole Director A-Award A Stock Option (right to buy) 15,000 14.88 223.2K 15,000
2021-06-10 SHENK THOMAS E Director A-Award A Restricted Share Units 15,000 0.00 15,000
2021-06-10 PERCEPTIVE ADVISORS LLC Director / 10% Owner A-Award A Stock Option (right to buy) 15,000 14.88 223.2K 15,000
2021-06-10 Mendoza Neil Director A-Award A Stock Option (right to buy) 15,000 14.88 223.2K 15,000
2021-06-10 MARCUS JOEL S Director A-Award A Restricted Share Units 15,000 0.00 15,000
2021-06-10 LEVINE ARNOLD J Director A-Award A Stock Option (right to buy) 15,000 14.88 223.2K 15,000
2021-06-10 Indyk Martin Director A-Award A Stock Option (right to buy) 15,000 14.88 223.2K 15,000
2021-06-10 Hukkelhoven Ellen Director A-Award A Stock Option (right to buy) 15,000 14.88 223.2K 15,000
2021-06-10 Harris Keith R. Director A-Award A Stock Option (right to buy) 20,000 14.88 297.6K 20,000
2021-06-09 Forbes Alexandria Director / Officer S-Sale D Ordinary Shares 4,153 15.04 62.5K 1,290,781
2021-06-08 Naylor Stuart Officer S-Sale D Ordinary Shares 5,040 15.01 75.7K 426,017
2021-06-08 Forbes Alexandria Director / Officer S-Sale D Ordinary Shares 20,180 15.02 303.1K 1,294,934
2021-06-07 Naylor Stuart Officer S-Sale D Ordinary Shares 1,042 15.02 15.7K 431,057
2021-06-07 Forbes Alexandria Director / Officer S-Sale D Ordinary Shares 5,667 15.03 85.2K 1,315,114
2021-04-30 Naylor Stuart Officer S-Sale D Ordinary Shares 741 15.01 11.1K 432,099 D
2021-04-29 Naylor Stuart Officer S-Sale D Ordinary Shares 1,405 15.02 21.1K 432,840 D
2021-04-28 Naylor Stuart Officer S-Sale D Ordinary Shares 3,772 15.14 57.1K 434,245 D
2021-03-15 MARCUS JOEL S Director M-Exempt A Ordinary Shares 12,882 7.72 99.4K 12,882
2021-03-05 Forbes Alexandria Director / Officer G-Gift D Orindary Shares 1,000 0.00 1,320,781
2021-02-17 Forbes Alexandria Director / Officer S-Sale D Ordinary Shares 15,000 15.57 233.6K 1,321,781
2021-02-16 Forbes Alexandria Director / Officer S-Sale D Ordinary Shares 15,000 15.60 234.0K 1,336,781
2021-01-14 Zeldin Robert K Officer A-Award A Stock Option (Right to Buy) 40,000 16.43 657.2K 40,000
2021-01-14 Wollin Robert J Officer A-Award A Restricted Share Units 20,000 0.00 20,000
2021-01-14 Naylor Stuart Officer A-Award A Stock Option (Right to Buy) 35,000 16.43 575.1K 35,000
2021-01-14 Giroux Richard Officer A-Award A Restricted Share Units 100,000 0.00 100,000
2021-01-14 Forbes Alexandria Director / Officer A-Award A Stock Option (Right to Buy) 65,000 16.43 1.07M 65,000
2021-01-05 Naylor Stuart Officer S-Sale D Ordinary Shares 6,000 15.34 92.0K 438,017
2021-01-04 Naylor Stuart Officer S-Sale D Ordinary Shares 6,000 15.40 92.4K 444,017
2020-12-31 Giroux Richard Officer I Orindary Shares 0 0.00 85,000
2020-12-31 Forbes Alexandria Director / Officer 0 0.00 0
2020-12-17 Giroux Richard Officer S-Sale D Ordinary Shares 18,000 16.00 288.0K 846,518
2020-12-17 Forbes Alexandria Director / Officer S-Sale D Ordinary Shares 13,390 15.00 200.9K 1,355,781
2020-11-23 PERCEPTIVE ADVISORS LLC Director / 10% Owner P-Purchase A Ordinary Shares 500,000 12.85 6.43M 6,933,277
2020-11-18 Forbes Alexandria Director / Officer S-Sale D Ordinary Shares 1,610 15.05 24.2K 1,369,171
2020-11-17 Forbes Alexandria Director / Officer S-Sale D Ordinary Shares 15,000 15.17 227.6K 1,370,781
2020-11-12 Forbes Alexandria Director / Officer S-Sale D Ordinary Shares 7,851 15.01 117.8K 1,388,748
2020-11-11 Forbes Alexandria Director / Officer S-Sale D Ordinary Shares 2,698 15.02 40.5K 1,394,672
2020-11-10 Naylor Stuart Officer S-Sale D Ordinary Shares 3,739 15.00 56.1K 451,129
2020-11-10 Forbes Alexandria Director / Officer S-Sale D Ordinary Shares 12,703 15.05 191.2K 1,399,097
2020-11-09 Naylor Stuart Officer S-Sale D Ordinary Shares 512 15.00 7.7K 454,868
2020-11-05 Naylor Stuart Officer S-Sale D Ordinary Shares 8,282 15.02 124.4K 455,380
2020-11-05 Forbes Alexandria Director / Officer S-Sale D Ordinary Shares 3,981 15.03 59.8K 1,411,800
2020-10-05 Naylor Stuart Officer S-Sale D Ordinary Shares 301 15.00 4.5K 463,662
2020-08-12 MARCUS JOEL S Director S-Sale D Ordinary Shares 7,959 14.15 112.6K 0
2020-08-11 MARCUS JOEL S Director S-Sale D Ordinary Shares 7,500 13.86 104.0K 7,959
2020-08-10 MARCUS JOEL S Director M-Exempt A Ordinary Shares 15,459 5.63 87.0K 15,459
2020-08-03 Zeldin Robert K Officer 0 0.00 0

Executive team

Top executives
EBIT / Employee
-282.6K
Shares Outstanding
92.56M

Executive compensation

Executive compensation (annual)
# Year Executive Salary Bonus Stock award Option award Incentive Other Total % Stock-
based
Filing
1 2025 Alexandria Forbes, Ph.D. President and Chief Executive Officer 840.0K 1.65M 5.82M 21.0K 8.33M 69.91%
2 2025 Richard Giroux Chief Financial Officer and Chief Operating Officer 714.0K 1.59M 5.82M 21.0K 8.15M 71.47%
3 2025 Robert K. Zeldin, M.D. Chief Medical Officer 543.4K 500.0K 551.7K 21.0K 1.62M 34.14%
4 2024 Alexandria Forbes, Ph.D. President and Chief Executive Officer 840.0K 2.20M 3.82M 20.7K 6.88M 55.55%
5 2024 Alexandria Forbes, Ph.D. President and Chief Executive Officer 840.0K 2.20M 3.82M 20.7K 6.88M 55.55%
6 2024 Richard Giroux Chief Financial Officer and Chief Operating Officer 714.0K 2.14M 3.82M 20.7K 6.69M 57.05%
7 2024 Richard Giroux Chief Financial Officer and Chief Operating Officer 714.0K 2.14M 3.82M 20.7K 6.69M 57.05%
8 2024 Stuart Naylor, Ph.D. Chief Development Officer 501.2K 600.0K 924.0K 2.03M 45.63%
9 2023 Alexandria Forbes, Ph.D. President and Chief Executive Officer 648.0K 2.20M 2.15M 1.30M 36.4K 6.34M 54.42%
10 2023 Richard Giroux Chief Financial Officer and Chief Operating Officer 544.0K 1.58M 2.06M 779.0K 19.8K 4.98M 57.07%
11 2023 Stuart Naylor, Ph.D. Chief Development Officer 462.1K 600.0K 860.0K 577.0K 2.50M 57.50%
12 2022 Alexandria Forbes, Ph.D. President and Chief Executive Officer 580.0K 1.72M 5.38M 37.7K 7.72M 69.77%
13 2022 Richard Giroux Chief Financial Officer and Chief Operating Officer 495.0K 1.32M 4.52M 18.3K 6.35M 71.19%
14 2022 Stuart Naylor, Ph.D. Chief Development Officer 442.9K 560.0K 3.23M 4.23M 76.30%
15 2021 Alexandria Forbes, Ph.D. President and Chief Executive Officer 580.0K 2.45M 1.97M 788.5K 31.9K 5.82M 47.41%
16 2021 Richard Giroux Chief Financial Officer and Chief Operating Officer 495.0K 1.88M 1.64M 485.2K 17.4K 4.52M 47.08%
17 2021 Robert K. Zeldin, M.D. 480.0K 600.0K 2.46M 485.2K 17.4K 4.05M 72.88%
18 2021 Stuart Naylor, Ph.D. Chief Development Officer 453.8K 800.0K 1.56M 424.6K 45.4K 3.28M 60.45%
19 2020 Alexandria Forbes, Ph.D. President and Chief Executive Officer 602.3K 1.86M 3.96M 1.84M 8.26M 47.94%
20 2020 Richard Giroux Chief Financial Officer and Chief Operating Officer 514.0K 1.44M 3.05M 1.84M 6.84M 44.55%
21 2020 Stuart Naylor, Ph.D. Chief Development Officer 424.9K 720.0K 3.25M 42.5K 4.44M 73.23%
22 2019 Alexandria Forbes, Ph.D. President and Chief Executive Officer 580.0K 3.16M 4.74M 8.48M 0.00%
23 2019 Richard Giroux Chief Financial Officer and Chief Operating Officer 495.0K 2.25M 4.73M 7.47M 0.00%
24 2019 Bruce Gottlieb 341.0K 450.0K 2.62M 3.41M 76.78%
25 2019 Stuart Naylor, Ph.D. Chief Development Officer 408.4K 640.0K 40.8K 1.09M 0.00%
26 2018 Alexandria Forbes, Ph.D. President and Chief Executive Officer 555.0K 3.03M 11.35M 1.38M 6.69M 23.00M 55.34%
27 2018 Richard Giroux Chief Operating Officer 476.7K 2.43M 11.35M 1.17M 6.67M 22.10M 56.64%
28 2018 Richard Giroux Chief Financial Officer and Chief Operating Officer 476.7K 2.43M 11.35M 1.17M 6.67M 22.10M 56.64%
29 2018 Stuart Naylor, Ph.D. Chief Development Officer 352.0K 750.0K 1.11M 35.2K 2.25M 49.36%
30 2017 Alexandria Forbes, Ph.D. President and Chief Executive Officer 450.0K 490.0K 166.0K 16.2K 1.12M 14.79%
31 2017 Richard Giroux Chief Financial Officer and Chief Operating Officer 400.0K 440.0K 153.2K 993.2K 15.43%
32 2017 Richard Giroux Chief Operating Officer 400.0K 440.0K 153.2K 993.2K 15.43%
33 2017 Stuart Naylor, Ph.D. Chief Development Officer 257.8K 528.9K 25.5K 25.8K 838.0K 3.05%
CEO compensation breakdown

Proxy statements

Proxy statements (DEF 14A)
Filing date Form type Filing
2026-04-30 DEFA14A
2026-04-30 DEF 14A
2025-04-30 DEFA14A
2025-04-30 DEF 14A

Recent SEC filings

Recent SEC filings
Filing date Form type Filing
2026-04-30 DEFA14A
2026-04-30 DEF 14A
2026-04-30 ARS
2026-04-28 4/A
2026-04-24 SC 13D/A
2026-04-24 8-K
2026-04-23 4
2026-04-21 4
2026-04-16 8-K
2026-04-16 8-K

Executive team

NameTitleCompensationGender
Alexandria Forbes Chief Executive Officer, President & Director 3M
Richard Brian Giroux Chief Operating Officer & Chief Financial Officer 2M male
Stuart Naylor Chief Development Officer 1M
Robert K. Zeldin Chief Medical Officer 1M
Christine Elise Sheehy Senior Vice President of Global Integration female
David Rubinstein Senior Vice President of Business Development
Tim Randall Senior Vice President of Risk & Internal Controls male
Robert J. Wollin General Counsel & Secretary male
Michel Michaelides Head of Clinical Ophthalmology
ESG Rating
B-
BIOTECHNOLOGY
Rank: 665 out of 710
2025
E (Environmental)
60.8 / 56.3
Company / Sector avg.
S (Social)
71.0 / 62.4
Company / Sector avg.
G (Governance)
40.2 / 60.9
Company / Sector avg.
ESG Total
57.4 / 59.9
Company / Sector avg.
ESG Score History BIOTECHNOLOGY
Benchmark vs Sector
Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend history

Earnings history

Earnings reports

Stock splits