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MBX Biosciences, Inc. Common Stock (MBX)

USD60.04 -1.01 (-1.65%)
US NASDAQ Healthcare Biotechnology
Address 11711 N. Meridian Street 46032
Carmel, IN, US
CEO Peter Kent Hawryluk
Website mbxbio.com
IPO 2000-01-14
CIK 1776111 ISIN US55287L1017

Explore sections of this company profile

Description

MBX Biosciences, Inc. is a biopharmaceutical company in its clinical development phase, dedicated to pioneering precise peptide-based therapies for endocrine and metabolic conditions. Its most advanced drug candidate, MBX 2109, is a parathyroid hormone peptide prodrug currently in Phase 2 clinical trials. This medication is being evaluated as a long-duration hormone replacement treatment for individuals suffering from chronic hypoparathyroidism. The company is also progressing with MBX 1416, a prolonged-action glucagon-like peptide-1 (GLP-1) receptor antagonist, which is undergoing Phase 1 clinical assessment. The aim of this therapy is to address post-bariatric hypoglycemia, a persistent complication often seen after weight-loss surgery. Furthermore, MBX Biosciences is developing MBX 4291, a key candidate for obesity treatment. This highly potent and long-acting prodrug functions as a co-agonist for both GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) receptors. It is currently in investigational new drug (IND)-enabling studies, with the intention of treating obesity and its associated health issues. Founded in 2018, the company's operations are headquartered in Carmel, Indiana.

News Sentiment (7d)
41 Neutral

Based on only 1 article — low confidence

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
USD60.04 -1.01 (-1.65%)
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Volume Profile
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Liquidity & share structure
Average Volume
761.9K
Beta
0.16
Float Shares
14.61M
Free Float %
43.5%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
-7.73% +15.56% +19.29% -2.68% +50.33% +17.25% +231.96% +56.36% +56.36% +56.36% +56.36%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
vs.
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Analyst Consensus (5 ratings, all time) Buy
Price Targets & DCF
Current price
60.04
Low 18.00 -70.0%
Consensus 60.33 +0.5%
Median 65.00 +8.3%
High 88.00 +46.6%
DCF (Unlevered) 2.02 -96.6%
DCF (Levered) 2.05 -96.6%

DCF figures are point estimates: small changes in growth or discount-rate assumptions move them materially. Read them as a reference, not a precise target.

Ratings Trend (MoM) 92% Bullish
Rating 2026-05 Change
Strong Buy 2 0
Buy 9 0
Hold 0 0
Sell 1 0
Strong Sell 0 0
Price Target Summary
Period # Analysts Avg Target
Last Month
Last Quarter 1
50.00
-16.7%
Last Year 7
52.86
-12.0%
All Time 8
51.75
-13.8%
Quality scores
Altman Z-Score
53.33
Safe zone
Piotroski F-Score
2 / 9
Weak
MOAT Score
3 / 10
No MOAT
Composite Rating
C
Overall Score
2 / 5
Medium
DCF Score
2 / 5
Medium
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
4 / 5
High
P/E Score
1 / 5
Low
P/Book Score
2 / 5
Medium
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
  • EPS growth Biotechnology: +29.7%
    -28.7% Q1'26: +29.6% (vs Q1'25)
  • FCF margin FCF growth · Biotechnology: +16.2%
  • EBIT margin Biotechnology: +0.0%
  • ROIC Biotechnology: -16.1%
    Q1'26: +6,546.2% (vs Q1'25)
  • Share dilution Biotechnology: -3.4%
    +9.3% Q1'26: +39.4% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    -0.01× Q1'26: -0.01× (vs Q1'25)
Valuation Multiples From To
DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (0.78) × ERP
WACC = 100% × Ke + 0% × Kd (4.0%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Intrinsic value (base): 2.02 Current price: 60.04
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2024
actual
Dec 2025
actual
Dec 2026
8 EPS Ana.
Dec 2027
7 EPS Ana.
Dec 2028
6 Rev. Ana.
7 EPS Ana.
Dec 2029
5 Rev. Ana.
2 EPS Ana.
Dec 2030
3 Rev. Ana.
5 EPS Ana.
Revenue
— – —
— – —
23.57M
23.57M – 23.57M
130.30M
130.30M – 130.30M
+452.8% YoY
272.01M
272.01M – 272.01M
+108.8% YoY
EBITDA
-67.95M
-98.06M
— – —
— – —
— – —
— – —
— – —
EBIT
-68.19M
-98.06M
— – —
— – —
— – —
— – —
— – —
Net Income
-61.92M
est: -486.68M (+87.3%)
-86.97M
est: -86.61M (-0.4%)
-103.22M
-111.51M – -94.92M
-19.2% YoY
-140.56M
-148.26M – -132.87M
-36.2% YoY
-128.79M
-194.36M – -63.21M
+8.4% YoY
-112.26M
-112.26M – -112.26M
+12.8% YoY
-56.89M
-56.89M – -56.89M
+49.3% YoY
SGA
10.78M
18.90M
— – —
— – —
— – —
— – —
— – —
EPS
-1.85
est: -11.52 (+83.9%)
-2.38
est: -2.47 (+3.5%)
-2.80
-3.05 – -2.60
-13.7% YoY
-3.87
-4.06 – -3.64
-37.9% YoY
-4.16
-5.32 – -1.73
-7.6% YoY
-3.08
-3.08 – -3.08
+26.0% YoY
-1.56
-1.56 – -1.56
+49.3% YoY
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-08 C 2/5 2/5 1/5 1/5 4/5 1/5 2/5
2026-05-07 C 2/5 2/5 1/5 1/5 4/5 1/5 2/5
2026-05-06 C 2/5 2/5 1/5 1/5 4/5 1/5 2/5
2026-05-05 C 2/5 2/5 1/5 1/5 4/5 1/5 2/5
2026-05-04 C 2/5 2/5 1/5 1/5 4/5 1/5 2/5
2026-05-01 C 2/5 2/5 1/5 1/5 3/5 1/5 2/5
2026-04-30 C 2/5 2/5 1/5 1/5 3/5 1/5 2/5
2026-04-29 C 2/5 2/5 1/5 1/5 3/5 1/5 2/5
2026-04-28 C 2/5 2/5 1/5 1/5 3/5 1/5 2/5
2026-04-27 C 2/5 2/5 1/5 1/5 3/5 1/5 2/5
2026-04-24 C 2/5 3/5 1/5 1/5 3/5 1/5 2/5
2026-04-23 C 2/5 3/5 1/5 1/5 2/5 1/5 2/5
2026-04-22 C 2/5 3/5 1/5 1/5 2/5 1/5 2/5
2026-04-21 C 2/5 3/5 1/5 1/5 2/5 1/5 2/5
2026-04-20 C 2/5 3/5 1/5 1/5 2/5 1/5 2/5
2026-04-17 C 2/5 3/5 1/5 1/5 2/5 1/5 2/5
2026-04-16 C 2/5 3/5 1/5 1/5 2/5 1/5 2/5
2026-04-15 C 2/5 3/5 1/5 1/5 2/5 1/5 2/5

Owner Earnings

Owner's Earnings (history)

Owner's Earnings history not available.

Owner alignment
Owner's Earnings TTM
OE per share TTM
Owner's Yield
Maintenance CapEx ratio
Maint CapEx / Avg PPE

Ownership Overview

Ownership breakdown
At a glance
Institutional holders
28
Total invested
67.00M
Insider transactions (90d)
3
Beneficial owners (>5%)
47
Beneficial owners (>5%)
# Reporting person Amount owned % of class Sole voting Shared voting Sole dispositive Shared dispositive Type Citizenship Filing date SEC filing
1 James N. Topper 5.99M 18.80% 5.99M 5.99M IN 2024-09-23
2 Patrick J. Heron 5.99M 18.80% 5.99M 5.99M IN 2024-09-23
3 FHMLS X, L.L.C. 4.55M 14.30% 4.55M 4.55M OO 2024-09-23
4 FHMLS X, L.P. 4.55M 14.30% 4.55M 4.55M PN 2024-09-23
5 Frazier Life Sciences X, L.P. 4.55M 14.30% 4.55M 4.55M PN 2024-09-23
6 OrbiMed Advisors LLC 3.81M 12.00% 3.81M 10.00 IA Delaware 2024-09-23
7 Ali Behbahani 3.61M 11.40% 3.61M 3.61M IN States 2024-09-23
8 Anthony A. Florence, Jr. 3.61M 11.40% 3.61M 3.61M IN States 2024-09-23
9 Baskett 3.61M 11.40% 3.61M 3.61M IN States 2024-09-23
10 Carmen Chang 3.61M 11.40% 3.61M 3.61M IN States 2024-09-23
11 D. Sandell 3.61M 11.40% 3.61M 3.61M IN States 2024-09-23
12 Edward T. Mathers 3.61M 11.40% 3.61M 3.61M IN States 2024-09-23
13 Mohamad H. Makhzoumi 3.61M 11.40% 3.61M 3.61M IN States 2024-09-23
14 NEA 17 GP, LLC 3.61M 11.40% 3.61M 3.61M OO Delaware 2024-09-23
15 NEA Partners 17, L.P. 3.61M 11.40% 3.61M 3.61M PN Delaware 2024-09-23
16 New Enterprise Associates 17, L.P. 3.61M 11.40% 3.61M 3.61M PN Delaware 2024-09-23
17 Paul Walker 3.61M 11.40% 3.61M 3.61M IN States 2024-09-23
18 Rick Yang 3.61M 11.40% 3.61M 3.61M IN States 2024-09-23
19 OrbiMed Capital GP VII LLC 3.16M 9.90% 3.16M 10.00 OO Delaware 2024-09-23
20 David Kroin 3.02M 9.48% 3.02M HC, IN Delaware 2024-09-23
21 Deep Track Biotechnology Master Fund, Ltd. 3.02M 9.48% 3.02M CO Delaware 2024-09-23
22 Deep Track Capital, LP 3.02M 9.48% 3.02M IA, OO Delaware 2024-09-23
23 Wellington Group Holdings LLP 2.94M 9.22% 2.79M HC Massachusetts 2024-11-08
24 Wellington Investment Advisors Holdings LLP 2.94M 9.22% 2.79M HC Massachusetts 2024-11-08
25 Wellington Management Group LLP 2.94M 9.22% 2.79M HC Massachusetts 2024-11-08
26 Wellington Management Company LLP 2.92M 9.17% 2.79M IA Massachusetts 2024-11-08
27 Genesis VC Partners XVI, LLC 2.14M 6.40% 2.14M 10.00 OO Delaware 2024-09-23
28 Jeffrey Crowe 2.14M 6.40% 2.14M 10.00 IN United States 2024-09-23
29 Jon E. Kossow 2.14M 6.40% 2.14M 10.00 IN United States 2024-09-23
30 NVP Associates, LLC 2.14M 6.40% 2.14M 10.00 OO Delaware 2024-09-23
31 Norwest Venture Partners XVI, LP 2.14M 6.40% 2.14M 10.00 PN Delaware 2024-09-23
32 Tiba Aynechi 2.14M 6.40% 2.14M 10.00 IN United States 2024-09-23
33 P. Kent Hawryluk 1.91M 5.55% 1.91M 1.91M IN United States of America 2024-11-01
34 Wellington Biomedical Innovation Master Investors (Cayman) II, L.P. 1.79M 5.62% 1.79M PN 2024-09-20
35 Albert Cha 1.43M 4.50% 1.43M 1.43M IN 2024-09-23
36 James Brush 1.43M 4.50% 1.43M 1.43M IN 2024-09-23
37 FHMLSP, L.L.C. 1.10M 3.50% 1.10M 1.10M OO 2024-09-23
38 FHMLSP, L.P. 1.10M 3.50% 1.10M 1.10M PN 2024-09-23
39 Frazier Life Sciences Public Fund, L.P. 1.10M 3.50% 1.10M 1.10M PN 2024-09-23
40 OrbiMed Genesis GP LLC 653.8K 2.10% 653.8K 10.00 OO Delaware 2024-09-23
41 FHMLSP Overage, L.L.C. 325.7K 1.00% 325.7K 325.7K OO 2024-09-23
42 FHMLSP Overage, L.P. 325.7K 1.00% 325.7K 325.7K PN 2024-09-23
43 Frazier Life Sciences Public Overage Fund, L.P. 325.7K 1.00% 325.7K 325.7K PN 2024-09-23
44 Daniel Estes 3.0K 0.00% 3.0K 3.0K IN 2024-09-23
45 FHMLS XI, L.L.C. 3.0K 0.00% 3.0K 3.0K OO 2024-09-23
46 FHMLS XI, L.P. 3.0K 0.00% 3.0K 3.0K PN 2024-09-23
47 Frazier Life Sciences XI, L.P. 3.0K 0.00% 3.0K 3.0K PN 2024-09-23

Institutional Activity (13F)

Institutional ownership trend From To
13F snapshot — 2026 Q1
Investors holding
28
-116 vs prev Q
New positions
7
Closed positions
118
Increased
14
Reduced
7
Put/Call ratio
0.00
Calls held
Puts held
Top institutional holders
# Investor Shares / Δ Mkt value / Δ Own% / Δ Weight% / Δ Avg px / Perf. Hold / Status
1 315.2K +315.2K (+100.0%) 9.94B +9.9B (+100.0%) 0.92% +0.922 pp 2.46% +2.456 pp USD31.54 +0.0% 1 qtrs NEW
2 FRAZIER LIFE SCIENCES MANAGEMENT, L.P. 6.65M +— (+0.0%) 209.80M +93.4M (+80.2%) 19.45% +0.000 pp 5.64% +2.147 pp USD25.13 +25.5% 6 qtrs
3 ORBIMED ADVISORS LLC 3.94M -67.7K (-1.7%) 124.12M +54.1M (+77.2%) 11.51% -0.198 pp 2.54% +0.893 pp USD25.09 +25.7% 6 qtrs
4 NEA MANAGEMENT COMPANY, LLC 3.61M +— (+0.0%) 114.00M +50.7M (+80.2%) 10.57% +0.000 pp 5.81% +2.342 pp USD25.98 +21.4% 6 qtrs
5 WELLINGTON MANAGEMENT GROUP LLP 3.35M -1.5M (-30.5%) 105.66M +21.2M (+25.2%) 9.80% -4.308 pp 0.02% +0.004 pp USD21.49 +46.8% 6 qtrs
6 DEEP TRACK CAPITAL, LP 3.25M +99.8K (+3.2%) 102.50M +47.4M (+85.9%) 9.50% +0.292 pp 1.83% +0.289 pp USD23.64 +33.4% 6 qtrs
7 BLACKROCK, INC. 2.92M +962.3K (+49.2%) 92.09M +57.8M (+168.8%) 8.54% +2.814 pp 0.00% +0.001 pp USD21.69 +45.4% 5 qtrs
8 NVP ASSOCIATES, LLC 2.14M +— (+0.0%) 67.38M +30.0M (+80.2%) 6.25% +0.000 pp 26.40% +3.887 pp USD25.98 +21.4% 6 qtrs
9 ECOR1 CAPITAL, LLC 2.12M +— (+0.0%) 66.98M +29.8M (+80.2%) 6.21% +0.000 pp 3.04% +1.256 pp USD21.82 +44.5% 6 qtrs
10 VANGUARD GROUP INC 1.82M +140.4K (+8.4%) 57.33M +28.0M (+95.3%) 5.32% +0.411 pp 0.00% +0.000 pp USD17.86 +76.6% 6 qtrs
11 DRIEHAUS CAPITAL MANAGEMENT LLC 1.41M -131.5K (-8.5%) 44.41M +17.5M (+64.8%) 4.12% -0.385 pp 0.30% +0.109 pp USD23.11 +36.5% 6 qtrs
12 CORMORANT ASSET MANAGEMENT, LP 1.12M -105.0K (-8.6%) 35.32M +13.9M (+64.8%) 3.28% -0.307 pp 1.63% +0.154 pp USD22.35 +41.1% 6 qtrs
13 BRAIDWELL LP 1.02M +1.0M (+100.0%) 32.13M +32.1M (+100.0%) 2.98% +2.979 pp 1.03% +1.027 pp USD31.54 +0.0% 1 qtrs NEW
14 WOODLINE PARTNERS LP 1.00M -201.1K (-16.7%) 31.54M +10.5M (+50.1%) 2.92% -0.588 pp 0.12% +0.023 pp USD18.85 +67.3% 6 qtrs
15 KYNAM CAPITAL MANAGEMENT, LP 934.8K -1.1M (-53.3%) 29.48M -5.5M (-15.8%) 2.73% -3.115 pp 1.88% -0.723 pp USD17.50 +80.2% 2 qtrs
16 EVENTIDE ASSET MANAGEMENT, LLC 890.0K +890.0K (+100.0%) 28.07M +28.1M (+100.0%) 2.60% +2.602 pp 0.44% +0.439 pp USD31.54 +0.0% 1 qtrs NEW
17 PARKMAN HEALTHCARE PARTNERS LLC 885.6K +112.3K (+14.5%) 27.93M +14.4M (+106.4%) 2.59% +0.329 pp 2.66% +1.248 pp USD14.52 +117.2% 5 qtrs
18 PRICE T ROWE ASSOCIATES INC /MD/ 840.5K -114.2K (-12.0%) 26.51M +9.8M (+58.7%) 2.46% -0.334 pp 0.00% +0.001 pp USD23.32 +35.2% 6 qtrs
19 CITADEL ADVISORS LLC 809.9K -186.2K (-18.7%) 25.54M +8.1M (+46.5%) 2.37% -0.545 pp 0.00% +0.001 pp USD17.50 +80.2% 2 qtrs
20 POINT72 ASSET MANAGEMENT, L.P. 680.6K +52.9K (+8.4%) 21.47M +10.5M (+95.4%) 1.99% +0.155 pp 0.02% +0.006 pp USD12.55 +151.3% 6 qtrs
21 STATE STREET CORP 672.7K +353.5K (+110.7%) 21.22M +15.6M (+279.8%) 1.97% +1.034 pp 0.00% +0.001 pp USD23.76 +32.7% 5 qtrs
22 D. E. SHAW & CO., INC. 671.8K +671.8K (+100.0%) 21.19M +21.2M (+100.0%) 1.96% +1.965 pp 0.01% +0.012 pp USD31.54 +0.0% 1 qtrs NEW
23 TCG CROSSOVER MANAGEMENT, LLC 650.0K +— (+0.0%) 20.50M +9.1M (+80.2%) 1.90% +0.000 pp 0.68% +0.119 pp USD25.98 +21.4% 6 qtrs
24 GEODE CAPITAL MANAGEMENT, LLC 649.4K +175.5K (+37.0%) 20.49M +12.2M (+146.9%) 1.90% +0.513 pp 0.00% +0.001 pp USD21.10 +49.5% 6 qtrs
25 MILLENNIUM MANAGEMENT LLC 462.0K -193.4K (-29.5%) 14.57M +3.1M (+27.1%) 1.35% -0.565 pp 0.01% +0.001 pp USD14.65 +115.3% 6 qtrs
26 SOLEUS CAPITAL MANAGEMENT, L.P. 408.9K +133.9K (+48.7%) 12.90M +8.1M (+168.0%) 1.20% +0.392 pp 0.48% +0.234 pp USD22.10 +42.7% 2 qtrs
27 GOLDMAN SACHS GROUP INC 331.9K -26.2K (-7.3%) 10.47M +4.2M (+67.1%) 0.97% -0.077 pp 0.00% +0.001 pp USD17.50 +80.2% 6 qtrs
28 ROCK SPRINGS CAPITAL MANAGEMENT LP 282.6K +— (+0.0%) 8.91M +4.0M (+80.2%) 0.83% +0.000 pp 0.46% +0.168 pp USD17.50 +80.2% 2 qtrs
29 UBS GROUP AG 281.2K +220.5K (+363.1%) 8.87M +7.8M (+734.6%) 0.82% +0.645 pp 0.00% +0.001 pp USD28.52 +10.6% 5 qtrs
30 OPALEYE MANAGEMENT INC. 260.0K +7.0K (+2.8%) 8.20M +3.8M (+85.2%) 0.76% +0.021 pp 1.08% +0.456 pp USD8.56 +268.5% 4 qtrs
31 AFFINITY ASSET ADVISORS, LLC 250.0K +85.0K (+51.5%) 7.89M +5.0M (+173.1%) 0.73% +0.249 pp 0.45% +0.198 pp USD22.27 +41.6% 4 qtrs
32 SUSQUEHANNA INTERNATIONAL GROUP, LLP 228.0K -258.8K (-53.2%) 7.19M -1.3M (-15.6%) 0.67% -0.757 pp 0.00% 0.000 pp USD16.79 +87.8% 3 qtrs
33 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 222.2K +52.2K (+30.7%) 7.01M +4.0M (+135.5%) 0.65% +0.153 pp 0.00% +0.001 pp USD20.78 +51.8% 5 qtrs
34 GOELZER INVESTMENT MANAGEMENT, INC. 221.7K +221.7K (+100.0%) 6.99M +7.0M (+100.0%) 0.65% +0.648 pp 0.32% +0.324 pp USD31.54 +0.0% 1 qtrs NEW
35 NORTHERN TRUST CORP 190.9K +57.6K (+43.2%) 6.02M +3.7M (+158.1%) 0.56% +0.169 pp 0.00% +0.001 pp USD21.26 +48.4% 5 qtrs
36 SCHONFELD STRATEGIC ADVISORS LLC 167.1K -115.6K (-40.9%) 5.27M +324.3K (+6.6%) 0.49% -0.338 pp 0.02% -0.005 pp USD11.38 +177.2% 5 qtrs
37 DAFNA CAPITAL MANAGEMENT LLC 165.3K +80.3K (+94.4%) 5.21M +3.7M (+250.4%) 0.48% +0.235 pp 1.21% +0.843 pp USD24.32 +29.7% 2 qtrs
38 683 CAPITAL MANAGEMENT, LLC 158.8K -125.0K (-44.0%) 5.01M +42.1K (+0.8%) 0.46% -0.366 pp 0.22% -0.042 pp USD17.50 +80.2% 2 qtrs
39 TFG ASSET MANAGEMENT GP LTD 143.3K -34.5K (-19.4%) 4.52M +1.4M (+45.3%) 0.42% -0.101 pp 0.95% +0.537 pp USD17.50 +80.2% 2 qtrs
40 TWO SIGMA INVESTMENTS, LP 138.6K +125.0K (+919.9%) 4.37M +4.1M (+1,738.1%) 0.41% +0.366 pp 0.01% +0.006 pp USD30.16 +4.6% 4 qtrs
41 BALYASNY ASSET MANAGEMENT L.P. 119.7K +94.1K (+366.9%) 3.78M +3.3M (+741.5%) 0.35% +0.275 pp 0.00% +0.004 pp USD28.53 +10.6% 2 qtrs
42 TD ASSET MANAGEMENT INC 101.5K -17.3K (-14.6%) 3.20M +1.1M (+53.9%) 0.30% -0.051 pp 0.00% +0.001 pp USD11.82 +166.8% 6 qtrs
43 BURKEHILL GLOBAL MANAGEMENT, LP 100.0K +— (+0.0%) 3.15M +1.4M (+80.2%) 0.29% +0.000 pp 0.21% +0.108 pp USD17.50 +80.2% 2 qtrs
44 JANE STREET GROUP, LLC 86.6K +86.6K (+100.0%) 2.73M +2.7M (+100.0%) 0.25% +0.253 pp 0.00% +0.000 pp USD31.54 +0.0% 1 qtrs NEW
45 PFM HEALTH SCIENCES, LP 79.3K -142.2K (-64.2%) 2.50M -1.4M (-35.5%) 0.23% -0.416 pp 0.25% -0.049 pp USD17.50 +80.2% 2 qtrs
46 STEMPOINT CAPITAL LP 78.6K +3.6K (+4.7%) 2.48M +1.2M (+88.8%) 0.23% +0.010 pp 0.42% +0.162 pp USD9.68 +225.8% 6 qtrs
47 ADVISOR GROUP HOLDINGS, INC. 77.6K +77.6K (+100.0%) 2.45M +2.4M (+100.0%) 0.23% +0.227 pp 0.00% +0.004 pp USD31.54 +0.0% 1 qtrs NEW
48 NUVEEN, LLC 75.6K +53.4K (+241.3%) 2.38M +2.0M (+515.0%) 0.22% +0.156 pp 0.00% +0.001 pp USD24.87 +26.8% 4 qtrs
49 BANK OF NEW YORK MELLON CORP 75.3K +27.5K (+57.7%) 2.37M +1.5M (+184.2%) 0.22% +0.081 pp 0.00% +0.000 pp USD21.79 +44.7% 5 qtrs
50 SCHRODER INVESTMENT MANAGEMENT GROUP 73.7K -10.0K (-12.0%) 2.28M +775.7K (+51.6%) 0.22% -0.029 pp 0.00% +0.001 pp USD17.50 +80.2% 2 qtrs
51 AARON WEALTH ADVISORS LLC 70.0K +20.0K (+40.0%) 2.21M +1.3M (+152.3%) 0.20% +0.059 pp 0.12% +0.069 pp USD14.28 +120.9% 4 qtrs
52 MANUFACTURERS LIFE INSURANCE COMPANY, THE 69.6K +1.2K (+1.7%) 2.15M +958.2K (+80.1%) 0.20% +0.003 pp 0.00% +0.001 pp USD19.60 +60.9% 6 qtrs
53 MORGAN STANLEY 59.0K +14.2K (+31.6%) 1.86M +1.1M (+137.1%) 0.17% +0.041 pp 0.00% +0.000 pp USD17.69 +78.3% 5 qtrs
54 VERITION FUND MANAGEMENT LLC 57.6K +57.6K (+100.0%) 1.82M +1.8M (+100.0%) 0.17% +0.168 pp 0.01% +0.007 pp USD31.54 +0.0% 1 qtrs NEW
55 EXODUSPOINT CAPITAL MANAGEMENT, LP 57.0K -43.0K (-43.0%) 1.80M +47.9K (+2.7%) 0.17% -0.126 pp 0.01% -0.004 pp USD17.50 +80.2% 2 qtrs
56 BARCLAYS PLC 52.7K +36.3K (+221.3%) 1.66M +1.2M (+290.0%) 0.15% +0.105 pp 0.00% +0.000 pp USD26.16 +20.6% 6 qtrs
57 ACADIAN ASSET MANAGEMENT LLC 48.6K +43.6K (+870.5%) 1.53M +1.4M (+1,679.1%) 0.14% +0.128 pp 0.00% +0.002 pp USD30.09 +4.8% 2 qtrs
58 SQUAREPOINT OPS LLC 46.7K +46.7K (+100.0%) 1.47M +1.5M (+100.0%) 0.14% +0.137 pp 0.00% +0.002 pp USD31.54 +0.0% 1 qtrs NEW
59 PLATINUM INVESTMENT MANAGEMENT LTD 43.6K -25.8K (-37.2%) 1.38M +160.1K (+13.2%) 0.13% -0.076 pp 0.32% +0.239 pp USD23.10 +36.5% 6 qtrs
60 BANK OF AMERICA CORP /DE/ 37.9K +11.3K (+42.4%) 1.20M +729.4K (+156.6%) 0.11% +0.031 pp 0.00% +0.000 pp USD18.47 +70.8% 5 qtrs
61 ALPS ADVISORS INC 36.9K +20.0K (+119.0%) 1.16M +868.2K (+294.6%) 0.11% +0.059 pp 0.01% +0.005 pp USD25.55 +23.4% 5 qtrs
62 CREATIVE PLANNING 33.7K +4.9K (+17.1%) 1.06M +558.5K (+111.1%) 0.10% +0.014 pp 0.00% +0.000 pp USD19.55 +61.3% 2 qtrs
63 RHUMBLINE ADVISERS 33.4K +11.6K (+53.2%) 1.05M +672.2K (+176.0%) 0.10% +0.034 pp 0.00% +0.001 pp USD20.08 +57.1% 5 qtrs
64 RENAISSANCE TECHNOLOGIES LLC 32.6K +32.6K (+100.0%) 1.03M +1.0M (+100.0%) 0.10% +0.096 pp 0.00% +0.002 pp USD31.54 +0.0% 1 qtrs NEW
65 WELLS FARGO & COMPANY/MN 31.9K +20.2K (+171.6%) 1.01M +801.4K (+389.6%) 0.09% +0.059 pp 0.00% +0.000 pp USD25.55 +23.4% 5 qtrs
66 AQR CAPITAL MANAGEMENT LLC 31.4K +15.6K (+99.2%) 990.6K +714.8K (+259.1%) 0.09% +0.046 pp 0.00% +0.000 pp USD21.44 +47.1% 3 qtrs
67 ALLIANCEBERNSTEIN L.P. 27.9K +17.4K (+165.7%) 880.0K +696.2K (+378.9%) 0.08% +0.051 pp 0.00% +0.000 pp USD23.96 +31.6% 3 qtrs
68 BREVAN HOWARD CAPITAL MANAGEMENT LP 25.7K +25.7K (+100.0%) 809.4K +809.4K (+100.0%) 0.08% +0.075 pp 0.01% +0.009 pp USD31.54 +0.0% 1 qtrs NEW
69 CAPTION MANAGEMENT, LLC 25.1K -49.9K (-66.5%) 791.7K -520.8K (-39.7%) 0.07% -0.146 pp 0.01% -0.005 pp USD17.50 +80.2% 2 qtrs
70 TREXQUANT INVESTMENT LP 24.3K +24.3K (+100.0%) 765.4K +765.4K (+100.0%) 0.07% +0.071 pp 0.01% +0.007 pp USD31.54 +0.0% 1 qtrs NEW
71 FOX RUN MANAGEMENT, L.L.C. 23.8K +23.8K (+100.0%) 751.3K +751.3K (+100.0%) 0.07% +0.070 pp 0.12% +0.116 pp USD31.54 +0.0% 1 qtrs NEW
72 QUBE RESEARCH & TECHNOLOGIES LTD 23.2K +23.2K (+100.0%) 732.1K +732.1K (+100.0%) 0.07% +0.068 pp 0.00% +0.001 pp USD31.54 +0.0% 1 qtrs NEW
73 CERITY PARTNERS LLC 21.3K +21.3K (+100.0%) 672.5K +672.5K (+100.0%) 0.06% +0.062 pp 0.00% +0.001 pp USD31.54 +0.0% 1 qtrs NEW
74 INVESCO LTD. 21.2K +9.4K (+79.9%) 668.7K +462.5K (+224.2%) 0.06% +0.028 pp 0.00% +0.000 pp USD23.73 +32.9% 2 qtrs
75 XTX TOPCO LTD 20.1K -18.2K (-47.5%) 635.2K -36.4K (-5.4%) 0.06% -0.053 pp 0.02% -0.018 pp USD15.62 +101.9% 3 qtrs
76 DEUTSCHE BANK AG\ 20.0K +9.1K (+83.3%) 631.7K +440.5K (+230.4%) 0.06% +0.027 pp 0.00% +0.000 pp USD21.85 +44.3% 5 qtrs
77 GSA CAPITAL PARTNERS LLP 19.3K +19.3K (+100.0%) 609.0K +609.0K (+100.0%) 0.06% +0.056 pp 0.05% +0.053 pp USD31.54 +0.0% 1 qtrs NEW
78 KOA WEALTH MANAGEMENT, LLC 18.4K -8.3K (-31.1%) 580.7K +113.3K (+24.2%) 0.05% -0.024 pp 0.40% +0.052 pp USD8.95 +252.4% 4 qtrs
79 CITIGROUP INC 16.4K +16.2K (+9,108.4%) 517.0K +513.9K (+16,490.9%) 0.05% +0.047 pp 0.00% +0.000 pp USD31.29 +0.8% 5 qtrs
80 METLIFE INVESTMENT MANAGEMENT, LLC 16.0K +5.0K (+45.4%) 505.2K +312.4K (+162.0%) 0.05% +0.015 pp 0.00% +0.002 pp USD17.69 +78.3% 5 qtrs
81 FMR LLC 15.7K -53.2K (-77.2%) 496.6K -710.5K (-58.9%) 0.05% -0.156 pp 0.00% +0.000 pp USD13.44 +134.7% 5 qtrs
82 CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD. 15.3K +10.3K (+206.3%) 483.1K +395.6K (+452.1%) 0.04% +0.030 pp 0.04% +0.030 pp USD26.96 +17.0% 2 qtrs
83 JPMORGAN CHASE & CO 14.6K +8.5K (+137.2%) 461.9K +353.8K (+327.4%) 0.04% +0.024 pp 0.00% +0.000 pp USD21.56 +46.3% 5 qtrs
84 MIRAE ASSET GLOBAL ETFS HOLDINGS LTD. 13.3K +6.1K (+86.2%) 418.2K +293.6K (+235.6%) 0.04% +0.018 pp 0.00% +0.000 pp USD23.22 +35.8% 5 qtrs
85 AMERICAN CENTURY COMPANIES INC 12.2K +12.2K (+100.0%) 385.9K +385.9K (+100.0%) 0.04% +0.036 pp 0.00% +0.000 pp USD31.54 +0.0% 1 qtrs NEW
86 CANADA PENSION PLAN INVESTMENT BOARD 11.6K +11.6K (+100.0%) 365.9K +365.9K (+100.0%) 0.03% +0.034 pp 0.00% +0.000 pp USD31.54 +0.0% 1 qtrs NEW
87 GRAHAM CAPITAL MANAGEMENT, L.P. 11.3K +11.3K (+100.0%) 355.0K +355.0K (+100.0%) 0.03% +0.033 pp 0.01% +0.009 pp USD31.54 +0.0% 1 qtrs NEW
88 BRIDGEWAY CAPITAL MANAGEMENT, LLC 10.0K -4.2K (-29.6%) 315.4K +66.9K (+26.9%) 0.03% -0.012 pp 0.01% +0.001 pp USD11.41 +176.4% 3 qtrs
89 GROUP ONE TRADING, L.P. 9.4K +9.4K (+100.0%) 297.4K +297.4K (+100.0%) 0.03% +0.028 pp 0.00% +0.001 pp USD31.54 +0.0% 1 qtrs NEW
90 PROFUND ADVISORS LLC 9.2K +9.2K (+100.0%) 290.6K +290.6K (+100.0%) 0.03% +0.027 pp 0.01% +0.009 pp USD31.54 +0.0% 1 qtrs NEW
91 SIMPLEX TRADING, LLC 8.9K +8.9K (+100.0%) 281.5K +281.5K (+100.0%) 0.03% +0.026 pp 0.00% +0.000 pp USD31.54 +0.0% 3 qtrs
92 VIRTUS INVESTMENT ADVISERS, INC. 8.9K -1.7K (-16.1%) 281.0K +95.3K (+51.3%) 0.03% -0.005 pp 0.08% +0.023 pp USD9.43 +234.5% 4 qtrs
93 LOS ANGELES CAPITAL MANAGEMENT LLC 10.4K +10.4K (+100.0%) 225.7K +225.7K (+100.0%) 0.03% +0.030 pp 0.00% +0.001 pp USD31.54 +0.0% 1 qtrs NEW
Ownership breakdown by holder

Insider Activity

Insider Activity — Latest Quarter
Ratio by transactions
1.00
Neutral
Ratio by volume
3.00
Bullish
Buys
2
Sells
2
Shares acquired
86.2K
Shares disposed
838.00
Cash buys
Cash sales
2.00
Net activity
+85,349
Insider buys vs sells (history) From To
Recent insider transactions From To
Date Person Role Transaction A/D Security Shares Price Value Owned after D/I Filing
2026-05-06 Hawryluk P. Kent Director / Officer S-Sale D Common Stock 607 29.54 17.9K 727,667 D
2026-05-06 Azoulay Salomon Officer S-Sale D Common Stock 231 29.54 6.8K 14,769 D
2026-05-01 Hoerter Steven L. Director A-Award A Stock option (right to buy) 74,249 29.78 2.21M 74,249 D
2026-03-16 Smither John W 0 0.00 0
2026-03-13 Hawryluk P. Kent Director / Officer P-Purchase A Common Stock 18,500 28.41 525.7K 486,777 I
2026-02-26 Hawryluk P. Kent Director / Officer M-Exempt A Common Stock 28,768 16.00 460.3K 728,274 D
2026-02-02 Hawryluk P. Kent Director / Officer A-Award A Common Stock 35,250 0.00 699,506 D
2026-02-02 Bartram Richard Officer A-Award A Stock option (right to buy) 70,000 39.07 2.73M 70,000 D
2026-02-02 Azoulay Salomon Officer A-Award A Stock option (right to buy) 70,000 39.07 2.73M 70,000 D
2026-01-20 Stelzer Laurie Director A-Award A Stock option (right to buy) 32,000 43.14 1.38M 32,000 D
2025-11-22 Hoerter Steven L. Director A-Award A Stock option (right to buy) 8,000 27.08 216.6K 8,000 D
2025-11-06 Hoerter Steven L. Director A-Award A Stock option (right to buy) 100,000 24.74 2.47M 100,000 D
2025-10-24 Hawryluk P. Kent Director / Officer M-Exempt A Common Stock 182,859 3.25 594.3K 664,256 D
2025-10-20 Hawryluk P. Kent Director / Officer P-Purchase A Common Stock 20,000 13.64 272.8K 468,277 I
2025-10-17 Hoerter Steven L. Director P-Purchase A Common Stock 20,000 13.25 265.0K 20,000 I
2025-09-26 Heron Patrick J Director / 10% Owner P-Purchase A Common Stock 666,666 18.00 12.00M 5,219,440 I
2025-06-05 Ryder Steven Director A-Award A Stock option (right to buy) 16,000 11.86 189.8K 16,000 D
2025-06-05 Pescovitz Ora H. Director A-Award A Stock option (right to buy) 16,000 11.86 189.8K 16,000 D
2025-06-05 Mathers Edward T Director / 10% Owner A-Award A Stock option (right to buy) 16,000 11.86 189.8K 16,000 D
2025-06-05 Hoerter Steven L. Director A-Award A Stock option (right to buy) 16,000 11.86 189.8K 16,000 D
2025-06-05 Heron Patrick J Director / 10% Owner A-Award A Stock option (right to buy) 16,000 11.86 189.8K 16,000 D
2025-06-05 CORNELIUS JAMES M Director A-Award A Stock option (right to buy) 16,000 11.86 189.8K 16,000 D
2025-06-05 Aynechi Tiba Director A-Award A Stock option (right to buy) 16,000 11.86 189.8K 16,000 D
2025-04-08 Pescovitz Ora H. Director P-Purchase A Common Stock 7,693 5.89 45.3K 24,329 D
2025-04-07 Hoerter Steven L. Director A-Award A Stock option (right to buy) 32,000 6.00 192.0K 32,000 D

Executive team

Top executives
Shares Outstanding
33.59M

Executive compensation

Executive compensation (annual)
# Year Executive Salary Bonus Stock award Option award Incentive Other Total % Stock-
based
Filing
1 2025 P. Kent Hawryluk President and Chief Executive Officer 625.0K 2.00M 359.4K 8.4K 2.99M 66.81%
2 2025 Richard Bartram Former Chief Financial Officer 484.0K 781.1K 222.6K 8.5K 1.50M 52.21%
3 2025 Salomon Azoulay, M.D. Chief Medical Officer 488.5K 740.0K 235.9K 10.5K 1.47M 50.17%
4 2024 Salomon Azoulay, M.D. Chief Medical Officer 234.4K 25.0K 2.74M 93.8K 3.10M 88.59%
5 2024 Salomon Azoulay, M.D. Chief Medical Officer 234.4K 25.0K 2.74M 93.8K 3.10M 88.59%
6 2024 P. Kent Hawryluk President and Chief Executive Officer 483.3K 1.45M 305.0K 2.24M 64.73%
7 2024 P. Kent Hawryluk President and Chief Executive Officer 483.3K 1.45M 305.0K 2.24M 64.73%
8 2024 Richard Bartram Former Chief Financial Officer 442.0K 511.6K 200.0K 1.15M 44.35%
9 2024 Richard Bartram Chief Financial Officer 442.0K 511.6K 200.0K 1.15M 44.35%
10 2023 P. Kent Hawryluk President and Chief Executive Officer 420.0K 4.29M 151.2K 4.86M 88.25%
11 2023 Richard Bartram Chief Financial Officer 425.0K 473.1K 153.0K 1.05M 45.01%
CEO compensation breakdown

Proxy statements

Proxy statements (DEF 14A)
Filing date Form type Filing
2026-05-08 DEFA14A
2026-04-22 DEFA14A
2026-04-22 DEF 14A
2025-04-23 DEFA14A
2025-04-23 DEF 14A

Recent SEC filings

Recent SEC filings
Filing date Form type Filing
2026-05-08 DEFA14A
2026-05-08 4
2026-05-08 4
2026-05-07 8-K
2026-05-07 10-Q
2026-05-06 SC 13G
2026-05-04 4
2026-04-27 SC 13G/A
2026-04-22 DEFA14A
2026-04-22 DEF 14A

Executive team

NameTitleCompensationGender
Peter Kent Hawryluk Chief Executive Officer, President & Director 992.8K male
Salomon Azoulay Chief Medical Officer 734.9K
Richard Bartram Chief Financial Officer 642.0K male
Steven L. Hoerter Executive Chairperson 40.5K male
Mark Hope Senior Vice President of Regulatory & Quality male
Michael A. Dorato DABT Sr. Vice President of Discovery & Non-Clinical Development
Andreas Moraitis Senior Vice President of Clinical Development
Pete De Spain Senior Vice President of Investor Relations & Corporate Communications male
Michelle Graham Chief Human Resources Officer female
Chatan Charan Senior Vice President of Pharmaceutical Development & Chemistry, Manufacturing and Controls
John W. Smither Interim Chief Financial Officer male
Karen Basbaum Chief Business Officer female
ESG Rating
B
BIOTECHNOLOGY
2026
E (Environmental)
59.8 / 56.3
Company / Sector avg.
S (Social)
73.4 / 62.4
Company / Sector avg.
G (Governance)
74.0 / 60.9
Company / Sector avg.
ESG Total
69.0 / 59.9
Company / Sector avg.
ESG Score History BIOTECHNOLOGY
Benchmark vs Sector
Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend history

Earnings history

Earnings reports

Stock splits