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Kaleido Biosciences, Inc. (KLDO)

USD0.00 +0.00 (+0.00%)
US OTC Healthcare Biotechnology
Address 65 Hayden Avenue 2421
Lexington, MA, US
CEO Mark A. Wingertzahn
IPO 2019-02-28
CIK 1751299 ISIN US4833471000

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Description

Kaleido Biosciences, Inc. is a clinical-stage healthcare firm dedicated to pioneering microbiome metabolic therapies. Its pipeline includes specific drug candidates such as KB195 for urea cycle disorders, KB295 targeting ulcerative colitis, KB174 aimed at hepatic encephalopathy, and KB109 for COVID-19. The company is also advancing programs in other significant therapeutic areas, including multi-drug resistant infections, chronic kidney disease, atherosclerotic cardiovascular disease, cardio-metabolic syndrome, immuno-oncology, and various inflammatory bowel conditions. Kaleido maintains strategic collaborations with Institute Gustave Roussy, Washington University, and Janssen. Established in 2015, its headquarters are situated in Lexington, Massachusetts.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
USD0.00 +0.00 (+0.00%)
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Volume Profile
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Liquidity & share structure
Average Volume
1.8K
Beta
-1.17
Float Shares
42.45M
Free Float %
99.6%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
+0.00% +0.00% +0.00% +9,900.00% +0.00% +0.00% +0.00% -50.00% -100.00% -100.00% -100.00%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
vs.
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Analyst Consensus (7 ratings, all time) Buy
Price Targets & DCF
Current price
0.00
DCF (Unlevered) 0.48 +479,915.2%
DCF (Levered) 0.35 +349,398.0%

DCF figures are point estimates: small changes in growth or discount-rate assumptions move them materially. Read them as a reference, not a precise target.

Ratings Trend (MoM) 0% Bullish
Rating 2024-11 Change
Strong Buy 0 0
Buy 0 0
Hold 0 0
Sell 1 0
Strong Sell 0 0
Quality scores
Altman Z-Score
-15.62
Distress
Piotroski F-Score
3 / 9
Average
MOAT Score
1 / 10
No MOAT
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
    +13.2% Q4'21: +102.5% (vs Q4'20)
  • EPS growth Biotechnology: +29.7%
    +11.5% Q4'21: +99.9% (vs Q4'20)
  • FCF margin FCF growth · Biotechnology: +16.2%
    -8,090.8% Q4'21: -3,576.4% (vs Q4'20)
  • EBIT margin Biotechnology: +0.0%
    -7,921.2% Q4'21: -3,975.0% (vs Q4'20)
  • ROIC Biotechnology: -16.1%
    Q4'21: +1,267.3% (vs Q4'20)
  • Share dilution Biotechnology: -3.4%
    +25.1% Q4'21: +16.3% (vs Q4'20)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    -0.25× Q4'21: -0.29× (vs Q4'20)
Valuation Multiples From To
Price Forecast (3Y) From To
Model
Adjust
P/E
Theoretical Return — If Invested Today

* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.

DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (-1.17) × ERP
WACC = 0% × Ke + 100% × Kd (13.1%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Intrinsic value (base): 0.48 Current price: 0.00
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2019
actual
Dec 2020
actual
Dec 2021
actual
Dec 2022
actual
Dec 2023
actual
Dec 2024
actual
Dec 2025
actual
Revenue
est: 13.75M (-100.0%)
975.0K
est: 12.20M (-92.0%)
1.10M
est: 1.67M (-33.9%)
1.00M
est.
30.00M
est.
97.98M
est.
150.47M
est.
EBITDA
-84.04M
est: 2.75M (-3,155.9%)
-77.00M
est: 2.44M (-3,255.7%)
-85.09M
est: 334.1K (-25,566.5%)
200.0K
est.
6.00M
est.
19.60M
est.
30.09M
est.
EBIT
-85.35M
est: 2.75M (-3,203.8%)
-78.82M
est: 2.44M (-3,330.4%)
-87.45M
est: 334.1K (-26,272.2%)
200.0K
est.
6.00M
est.
19.60M
est.
30.09M
est.
Net Income
-85.01M
est: -104.96M (+19.0%)
-81.62M
est: -96.28M (+15.2%)
-90.29M
est: -94.67M (+4.6%)
-48.56M
est.
-35.58M
est.
-8.79M
est.
25.95M
est.
SGA
22.43M
est: 127.84M (-82.5%)
23.88M
est: 113.42M (-78.9%)
20.97M
est: 15.53M (+35.0%)
9.30M
est.
278.92M
est.
910.93M
est.
1.40B
est.
EPS
-3.31
est: -2.51 (-32.0%)
-2.44
est: -2.30 (-6.1%)
-2.16
est: -2.26 (+4.5%)
-1.16
est.
-0.85
est.
-0.21
est.
0.62
est.

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
-79.86M
OE per share TTM
-1.92
Owner's Yield
-1,907,675.35%
Maintenance CapEx ratio
Maint CapEx / Avg PPE
1,349.0%

Ownership Overview

Ownership breakdown

Ownership breakdown not available.

At a glance
Institutional holders
Total invested
Insider transactions (90d)
0
Beneficial owners (>5%)
3
Beneficial owners (>5%)
# Reporting person Amount owned % of class Sole voting Shared voting Sole dispositive Shared dispositive Type Citizenship Filing date SEC filing
1 Abigail P. Johnson 2.09M 6.94% 2.09M IN United States of America 2020-02-07
2 FMR LLC 2.09M 6.94% 784.9K 2.09M HC Delaware 2020-02-07
3 1,833,832 1.83M 12.00% 1.83M 1.83M OO 2021-02-16

Institutional Activity (13F)

Institutional ownership trend

Institutional history not available.

Top institutional holders

Top holders not available.

ETF Ownership

Top ETFs holding this stock Held by 1 ETFs in our universe
# ETF Weight Est. AUM exposure TER
1 Xtrackers Russell 2000 UCITS ETF 1C XRSU.L 0.00% 0.86 0.30%

Insider Activity

Insider Activity — Latest Quarter
Ratio by transactions
4.50
Bullish
Ratio by volume
3.00
Bullish
Buys
9
Sells
2
Shares acquired
1.31M
Shares disposed
4.1K
Cash buys
Cash sales
Net activity
+1,303,097
Insider buys vs sells (history) From To
Recent insider transactions From To
Date Person Role Transaction A/D Security Shares Price Value Owned after D/I Filing
2022-02-28 van Hylckama Vlieg Johan Officer F-InKind D Restricted Stock Units 2,087 1.49 3.1K 4,620
2022-02-28 Korn Jerald Officer F-InKind D Restricted Stock Units 2,046 1.49 3.0K 4,517
2022-01-14 van Hylckama Vlieg Johan Officer A-Award A Restricted Stock Units 350,000 0.00 350,000
2022-01-14 Menichella Daniel L Director / Officer A-Award A Restricted Stock Units 250,000 0.00 250,000
2022-01-14 Long Alison S Officer A-Award A Restricted Stock Units 125,000 0.00 125,000
2022-01-14 Korn Jerald Officer A-Award A Restricted Stock Units 250,000 0.00 250,000
2022-01-14 Duke William E. Officer A-Award A Restricted Stock Units 125,000 0.00 125,000
2021-12-15 Long Alison S Officer A-Award A Stock Option (Right to Buy) 300,000 3.08 924.0K 300,000
2021-09-01 van Hylckama Vlieg Johan Officer A-Award A Stock Option (Right to Buy) 40,000 6.29 251.6K 40,000
2021-09-01 Menichella Daniel L Director / Officer A-Award A Stock Option (Right to Buy) 110,000 6.29 691.9K 110,000
2021-09-01 Korn Jerald Officer A-Award A Stock Option (Right to Buy) 100,000 6.29 629.0K 100,000
2021-09-01 Duke William E. Officer A-Award A Stock Option (Right to Buy) 60,000 6.29 377.4K 60,000
2021-06-30 von Maltzahn Geoffrey Director A-Award A Stock Option (Right to Buy) 15,000 7.44 111.6K 15,000
2021-06-30 Quinn Anthony G. Director A-Award A Stock Option (Right to Buy) 15,000 7.44 111.6K 15,000
2021-06-30 Prener Anne Director A-Award A Stock Option (Right to Buy) 15,000 7.44 111.6K 15,000
2021-06-30 Mixer Jean K Director A-Award A Stock Option (Right to Buy) 15,000 7.44 111.6K 15,000
2021-06-30 MELAS KYRIAZI THEO Director A-Award A Stock Option (Right to Buy) 15,000 7.44 111.6K 15,000
2021-06-30 Burnett Grady Director A-Award A Stock Option (Right to Buy) 15,000 7.44 111.6K 15,000
2021-06-30 Bassler Bonnie L Director A-Award A Stock Option (Right to Buy) 15,000 7.44 111.6K 15,000
2021-06-30 BONNEY MICHAEL W Director A-Award A Stock Option (Right to Buy) 15,000 7.44 111.6K 15,000
2021-05-05 van Hylckama Vlieg Johan Officer D Stock Option (Right to Buy) 125,000 7.67 958.8K 0
2021-03-01 Menichella Daniel L Director / Officer A-Award A Stock Option (Right to Buy) 90,000 9.81 882.9K 90,000
2021-03-01 Korn Jerald Officer A-Award A Stock Option (Right to Buy) 60,000 9.81 588.6K 60,000
2021-03-01 Duke William E. Officer A-Award A Stock Option (Right to Buy) 60,000 9.81 588.6K 60,000
2021-02-08 Menichella Daniel L Director / Officer P-Purchase A Common Stock 20,000 11.50 230.0K 20,000
2021-02-08 Flagship Ventures Fund IV General Partner LLC 10% Owner P-Purchase A Common Stock 71,667 11.50 824.2K 2,982,639
2020-10-15 Menichella Daniel L Director / Officer A-Award A Stock Option (Right to Buy) 600,000 8.69 5.21M 600,000
2020-10-15 Korn Jerald Officer A-Award A Stock Option (Right to Buy) 45,000 8.69 391.1K 45,000
2020-10-15 Knobil Katharine Officer A-Award A Stock Option (Right to Buy) 67,500 8.69 586.6K 67,500
2020-10-15 Duke William E. Officer A-Award A Stock Option (Right to Buy) 50,000 8.69 434.5K 50,000
2020-10-13 Menichella Daniel L Director / Officer 0 0.00 0
2020-06-30 von Maltzahn Geoffrey Director A-Award A Stock Option (Right to Buy) 15,000 7.43 111.5K 15,000
2020-06-30 Quinn Anthony G. Director A-Award A Stock Option (Right to Buy) 15,000 7.43 111.5K 15,000
2020-06-30 Prener Anne Director A-Award A Stock Option (Right to Buy) 15,000 7.43 111.5K 15,000
2020-06-30 Mixer Jean K Director A-Award A Stock Option (Right to Buy) 15,000 7.43 111.5K 15,000
2020-06-30 MELAS KYRIAZI THEO Director A-Award A Stock Option (Right to Buy) 15,000 7.43 111.5K 15,000
2020-06-30 Burnett Grady Director A-Award A Stock Option (Right to Buy) 15,000 7.43 111.5K 15,000
2020-06-30 Bassler Bonnie L Director A-Award A Stock Option (Right to Buy) 15,000 7.43 111.5K 15,000
2020-06-30 BONNEY MICHAEL W Director A-Award A Stock Option (Right to Buy) 15,000 7.42 111.3K 15,000
2020-06-04 Nutritional Health LTP Fund General Partner LLC 10% Owner I Common Stock 0 0.00 666,666
2020-06-04 MELAS KYRIAZI THEO Director P-Purchase A Common Stock 33,333 7.50 250.0K 33,333
2020-06-04 Flagship Ventures Fund IV General Partner LLC 10% Owner P-Purchase A Common Stock 666,667 7.50 5.00M 2,910,972
2020-04-15 Lawton Alison Frances Director / Officer A-Award A Stock Option (Right to Buy) 118,500 6.00 711.0K 118,500
2020-04-15 Korn Jerald Officer A-Award A Stock Option (Right to Buy) 45,000 6.00 270.0K 45,000
2020-04-15 Knobil Katharine Officer A-Award A Stock Option (Right to Buy) 67,500 6.00 405.0K 67,500
2020-04-15 Duke William E. Officer A-Award A Stock Option (Right to Buy) 50,000 6.00 300.0K 50,000
2020-04-01 Prener Anne Director A-Award A Stock Option (Right to Buy) 30,000 5.21 156.3K 30,000
2020-02-28 Lawton Alison Frances Director / Officer A-Award A Restricted Stock Units 46,325 0.00 46,325
2020-02-28 Korn Jerald Officer A-Award A Restricted Stock Units 6,563 0.00 6,563
2020-02-28 Knobil Katharine Officer A-Award A Restricted Stock Units 15,843 0.00 15,843
2019-11-29 Duke William E. Officer A-Award A Stock Option (Right to Buy) 270,000 8.71 2.35M 270,000
2019-11-22 Duke William E. Officer 0 0.00 0
2019-11-15 Lawton Alison Frances Director / Officer A-Award D Stock Option (Right to Buy) 150,000 6.56 984.0K 150,000
2019-11-15 Korn Jerald Officer A-Award A Stock Option (Right to Buy) 75,000 6.56 492.0K 75,000
2019-11-15 Knobil Katharine Officer A-Award A Stock Option (Right to Buy) 125,000 6.56 820.0K 125,000
2019-10-11 Scalzo Richard William Officer D Stock Option (Right to Buy) 37,500 10.28 385.5K 0
2019-09-30 Mixer Jean K Director A-Award A Stock Option (Right to Buy) 97,626 7.53 735.1K 97,626
2019-07-31 MELAS KYRIAZI THEO Director A-Award A Stock Option (Right to Buy) 93,531 7.67 717.4K 93,531
2019-07-31 Korn Jerald Officer A-Award A Stock Option (Right to Buy) 180,000 7.67 1.38M 180,000
2019-07-22 Korn Jerald Officer 0 0.00 0
2019-07-11 MELAS KYRIAZI THEO Director 0 0.00 0
2019-03-04 von Maltzahn Geoffrey Director C-Conversion A Common Stock 342,466 0.00 342.47 342,466
2019-03-04 Quinn Anthony G. Director C-Conversion A Common Stock 12,853 0.00 12.85 31,603
2019-03-04 Lawton Alison Frances Director / Officer A-Award A Stock Option (Right to Buy) 150,000 15.00 2.25M 150,000
2019-03-04 Flagship Ventures Fund V General Partner LLC Director / 10% Owner C-Conversion D Series B Preferred Stock 2,570,694 0.00 0
2019-03-04 Flagship Ventures Fund IV General Partner LLC Director / 10% Owner C-Conversion A Common Stock 665,908 0.00 665.91 665,908
2019-03-04 Brumm Joshua T Officer A-Award A Stock Option (Right to Buy) 80,000 15.00 1.20M 80,000
2019-03-04 BONNEY MICHAEL W Director / Officer C-Conversion D Series B Preferred Stock 450,000 0.00 0
2019-02-28 BONNEY MICHAEL W Director / Officer P-Purchase A Common Stock 68,965 13.95 962.1K 1,005,968
2019-02-27 von Maltzahn Geoffrey Director D Series A Preferred Stock 342,466 0.00 0
2019-02-27 SCULLEY JOHN Director D Stock Option (Right to Buy) 50,000 15.20 760.0K 0
2019-02-27 Quinn Anthony G. Director D Stock Option (Right to Buy) 31,250 0.30 9.4K 0
2019-02-27 McIntyre Jonathan Director D Stock Option (Right to Buy) 5,000 2.18 10.9K 0
2019-02-27 Lawton Alison Frances Director / Officer D Stock Option (Right to Buy) 162,500 2.22 360.8K 0
2019-02-27 Knobil Katharine Officer D Stock Option (Right to Buy) 461,000 17.40 8.02M 0
2019-02-27 Flagship Ventures Fund V General Partner LLC Director / 10% Owner I Series A Preferred Stock 4,637,555 0.00 0
2019-02-27 Flagship Ventures Fund IV General Partner LLC Director / 10% Owner I Series A-1 Preferred Stock 281,203 0.00 0
2019-02-27 Burnett Grady Director D Stock Option (Right to Buy) 50,000 11.78 589.0K 0
2019-02-27 Brumm Joshua T Officer D Stock Option (Right to Buy) 124,089 10.28 1.28M 0
2019-02-27 Bassler Bonnie L Director D Stock Option (Right to Buy) 50,000 17.40 870.0K 0
2019-02-27 BONNEY MICHAEL W Director / Officer D Common Stock 0 0.00 937,003

Executive team

Top executives
EBIT / Employee
-11.5K
Shares Outstanding
42.62M

Executive compensation

Executive compensation (annual)
# Year Executive Salary Bonus Stock award Option award Incentive Other Total % Stock-
based
Filing
1 2020 Daniel Menichella President and Chief Executive Officer (principal executive officer) 118.7K 3.78M 49.0K 1.7K 3.95M 95.71%
2 2020 Katharine Knobil, M.D. Former CMO Head of RD 450.0K 75.7K 805.8K 157.6K 12.5K 1.50M 53.66%
3 2020 William Duke, Jr. Chief Financial Officer (principal financial officer) 420.0K 100.0K 527.1K 142.8K 10.1K 1.20M 43.92%
4 2020 Alison Lawton Former President and Chief Executive Officer (former principal executive officer) 515.0K 351.7K 257.5K 11.3K 1.14M 30.98%
5 2019 Alison Lawton Former President and Chief Executive Officer (former principal executive officer) 500.0K 250.0K 2.10M 276.6K 11.2K 3.14M 66.94%
6 2019 Alison Lawton President and Chief Executive Officer (principal executive officer) 500.0K 2.10M 276.6K 11.2K 2.89M 72.73%
7 2019 William Duke, Jr. Chief Financial Officer (principal financial officer) 44.7K 1.68M 277.00 1.72M 97.39%
8 2019 Jerald Korn 170.0K 50.0K 1.21M 70.5K 4.2K 1.51M 80.42%
9 2019 Katharine Knobil, M.D. Former CMO Head of RD 450.0K 200.0K 583.7K 170.3K 47.8K 1.45M 40.21%
10 2019 Katharine Knobil, M.D. Chief Medical Officer and Head of Research Development 450.0K 583.7K 170.3K 47.8K 1.25M 46.63%
11 2019 Joshua Brumm Chief Operating Officer and Chief Financial Officer (former principal financial officer) 349.9K 747.2K 764.00 1.10M 68.06%
12 2019 Daniel Menichella President and Chief Executive Officer (principal executive officer)
13 2018 Alison Lawton President and Chief Executive Officer (principal executive officer) 437.5K 5.95M 250.0K 9.5K 6.64M 89.51%
14 2018 Katharine Knobil, M.D. Chief Medical Officer and Head of Research Development 37.5K 3.90M 200.4K 4.14M 94.25%
15 2018 Joshua Brumm Chief Operating Officer and Chief Financial Officer (former principal financial officer) 296.9K 2.11M 126.1K 320.6K 2.85M 73.92%
CEO compensation breakdown

Proxy statements

Proxy statements (DEF 14A)
Filing date Form type Filing
2021-05-05 DEFA14A
2021-05-05 DEF 14A

Recent SEC filings

Recent SEC filings
Filing date Form type Filing
2022-05-10 SC 13G/A
2022-05-06 15-12B
2022-05-02 EFFECT
2022-04-25 S-8 POS
2022-04-25 S-8 POS
2022-04-25 S-8 POS
2022-04-25 POS AM
2022-04-18 25
2022-04-08 8-K
2022-04-01 NT 10-K

Executive team

NameTitleCompensationGender
Mark A. Wingertzahn Senior Vice President of R&D and Head of Development
ESG Rating
B
BIOTECHNOLOGY
2021
E (Environmental)
54.2 / 56.3
Company / Sector avg.
S (Social)
66.2 / 62.4
Company / Sector avg.
G (Governance)
63.9 / 60.9
Company / Sector avg.
ESG Total
61.4 / 59.9
Company / Sector avg.
ESG Score History BIOTECHNOLOGY
Benchmark vs Sector
Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend history

Earnings history

Earnings reports

Stock splits