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Public Joint-Stock Company "Human Stem Cells Institute" (ISKJ.ME)

RUB36.64 -1.06 (-2.81%)
RU MCX Healthcare Biotechnology
Address 18/1 Olimpiysky prospect 129110
Moscow, RU
CEO Artur Alexandrovich Isaev
Website hsci.ru
IPO 2010-03-03
ISIN RU000A0JNAB6

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Description

Public Joint-Stock Company "Human Stem Cells Institute," identified by the symbol ISKJ.ME, operates primarily as a biotechnology enterprise within Russia. The company focuses on pharmaceutical innovation, encompassing research, development, and the commercialization of its proprietary offerings in various therapeutic areas. These include regenerative medicine, bio-insurance, medical genetics (with a specific emphasis on reproductive applications), gene therapy, and biopharmaceutics. The institute manages Gemabank, a prominent family cord blood stem cell repository serving Russia and the Commonwealth of Independent States (CIS), and Reprobank, a facility for the personal cryopreservation of reproductive cells and tissues, which also facilitates sperm and oocyte donations. Among its key products is Neovasculgen, a gene-therapy medication for treating peripheral arterial disease, including critical limb ischemia. It also offers SPRS-therapy, a customized diagnostic and treatment approach designed for repairing skin damage. Furthermore, the company operates GENETICO, a specialized medical genetics center and molecular diagnostic laboratory. GENETICO delivers extensive genetic analysis and counseling services aimed at the early identification, prediction, and preventative management of genetic disorders, particularly those affecting the reproductive system. Its services extend to preimplantation genetic diagnostics and screening, involving the examination of developing embryos for hereditary monogenic conditions and chromosomal irregularities during in vitro fertilization cycles. The company additionally provides non-invasive prenatal testing to detect fetal chromosome abnormalities and is actively developing Gemacell, an investigational cell-based therapy targeting myocardial infarction. Beyond these, the firm supplies diagnostic services to uncover genetic predispositions to oncological diseases and distributes specialized equipment for cell processing. Established in Moscow, Russia, in 2003, Public Joint-Stock Company "Human Stem Cells Institute" functions as a subsidiary of PJSC International Medical Center Processings and Kriokhraneniya of Biomaterialy.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Indicator 1D1W2W3W1M
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Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
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Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
RUB36.64 -1.06 (-2.81%)
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Volume Profile
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Liquidity & share structure
Average Volume
1M
Beta
0.30
Float Shares
4.67M
Free Float %
5.7%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
-1.55% -17.08% -18.46% -30.25% -32.66% -30.76% -40.81% -55.44% +25.17% +102.15% +279.03%
Rolling Volatility
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Relative Strength
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Monthly Returns Heatmap
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Daily Returns Distribution
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Financial Statements

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Market Data

Price Targets & DCF
Current price
36.64
DCF (Unlevered) 27.15 -25.9%
DCF (Levered) 164.87 +350.0%

DCF figures are point estimates: small changes in growth or discount-rate assumptions move them materially. Read them as a reference, not a precise target.

Ratings Trend (MoM)
Rating 2024-06 Change
Strong Buy 0 0
Buy 0 0
Hold 0 0
Sell 0 0
Strong Sell 0 0
Quality scores
Altman Z-Score
2.63
Grey zone
Piotroski F-Score
5 / 9
Average
MOAT Score
4 / 10
Developing
Composite Rating
B
Overall Score
3 / 5
Medium
DCF Score
5 / 5
High
ROE Score
5 / 5
High
ROA Score
4 / 5
High
D/E Score
1 / 5
Low
P/E Score
1 / 5
Low
P/Book Score
1 / 5
Low
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
    +12.8% Q4'25: +126.0% (vs Q3'24)
  • EPS growth Biotechnology: +29.7%
    -44.4% Q4'25: -128.1% (vs Q3'24)
  • FCF margin FCF growth · Biotechnology: +16.2%
    -4.0% Q4'25: +1.1% (vs Q3'24)
  • EBIT margin Biotechnology: +0.0%
    +7.0% Q4'25: +0.8% (vs Q3'24)
  • ROIC Biotechnology: -16.1%
    +8.7% Q4'25: +1.4% (vs Q3'24)
  • Share dilution Biotechnology: -3.4%
    -18.9% Q4'25: +0.2% (vs Q3'24)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    3.68× Q4'25: 2.85× (vs Q3'24)
Valuation Multiples From To
Price Forecast (3Y) From To
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P/E
Theoretical Return — If Invested Today

* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.

DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (0.29) × ERP
WACC = 79% × Ke + 21% × Kd (10.5%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Intrinsic value (base): 27.15 Current price: 36.64
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-30 B 3/5 5/5 5/5 4/5 1/5 1/5 1/5
2026-05-29 B 3/5 5/5 5/5 4/5 1/5 1/5 1/5
2026-05-28 B 3/5 5/5 5/5 4/5 1/5 1/5 1/5
2026-05-27 B 3/5 5/5 5/5 4/5 1/5 1/5 1/5
2026-05-26 B 3/5 5/5 5/5 4/5 1/5 1/5 1/5
2026-05-25 B 3/5 5/5 5/5 4/5 1/5 1/5 1/5
2026-05-24 B 3/5 5/5 5/5 4/5 1/5 1/5 1/5
2026-05-23 B 3/5 5/5 5/5 4/5 1/5 1/5 1/5
2026-05-22 B 3/5 5/5 5/5 4/5 1/5 1/5 1/5
2026-05-21 B 3/5 5/5 5/5 4/5 1/5 1/5 1/5
2026-05-20 B 3/5 5/5 4/5 4/5 1/5 1/5 1/5
2026-05-19 B 3/5 5/5 4/5 4/5 1/5 1/5 1/5
2026-05-18 B 3/5 5/5 4/5 4/5 1/5 1/5 1/5
2026-05-17 B 3/5 5/5 4/5 4/5 1/5 1/5 1/5
2026-05-16 B 3/5 5/5 4/5 4/5 1/5 1/5 1/5
2026-05-15 A- 4/5 5/5 3/5 4/5 3/5 1/5 4/5
2026-05-14 A- 4/5 5/5 3/5 4/5 3/5 1/5 4/5
2026-05-13 A- 4/5 5/5 3/5 4/5 3/5 1/5 4/5
2026-05-12 A- 4/5 5/5 3/5 4/5 3/5 1/5 4/5
2026-05-11 A- 4/5 5/5 3/5 4/5 3/5 1/5 4/5
2026-05-08 B+ 3/5 5/5 2/5 4/5 3/5 1/5 4/5
2026-05-07 B+ 3/5 5/5 2/5 4/5 3/5 1/5 4/5
2026-05-06 B+ 3/5 5/5 2/5 4/5 3/5 1/5 4/5
2026-05-05 B+ 3/5 5/5 2/5 4/5 3/5 1/5 4/5
2026-05-04 B+ 3/5 5/5 2/5 4/5 3/5 1/5 4/5
2026-05-03 B+ 3/5 5/5 2/5 4/5 3/5 1/5 4/5
2026-05-02 B+ 3/5 5/5 2/5 4/5 3/5 1/5 4/5
2026-04-30 B+ 3/5 5/5 2/5 4/5 3/5 1/5 4/5
2026-04-29 B+ 3/5 5/5 2/5 4/5 3/5 1/5 4/5
2026-04-28 B+ 3/5 5/5 2/5 4/5 3/5 1/5 4/5
2026-04-27 B+ 3/5 5/5 2/5 4/5 3/5 1/5 4/5
2026-04-26 B+ 3/5 5/5 2/5 4/5 3/5 1/5 4/5
2026-04-25 B+ 3/5 5/5 2/5 4/5 2/5 1/5 4/5
2026-04-24 B+ 3/5 5/5 2/5 4/5 2/5 1/5 4/5
2026-04-23 B+ 3/5 5/5 2/5 4/5 2/5 1/5 4/5
2026-04-22 B+ 3/5 5/5 2/5 4/5 2/5 1/5 4/5
2026-04-21 B+ 3/5 5/5 2/5 5/5 2/5 1/5 4/5
2026-04-20 B+ 3/5 5/5 2/5 5/5 2/5 1/5 4/5
2026-04-19 B+ 3/5 5/5 2/5 5/5 2/5 1/5 4/5
2026-04-18 B+ 3/5 5/5 2/5 5/5 2/5 1/5 4/5
2026-04-17 B+ 3/5 5/5 2/5 5/5 2/5 1/5 4/5
2026-04-16 B+ 3/5 5/5 2/5 5/5 2/5 1/5 4/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
402.21M
OE per share TTM
5.18
Owner's Yield
11.58%
Maintenance CapEx ratio
Maint CapEx / Avg PPE
26.5%

Ownership Overview

Ownership breakdown

Ownership breakdown not available.

At a glance
Institutional holders
Total invested
Insider transactions (90d)
0
Beneficial owners (>5%)
0
Beneficial owners (>5%)

No beneficial ownership filings recorded.

Institutional Activity (13F)

Institutional ownership trend

Institutional history not available.

Top institutional holders

Top holders not available.

ETF Ownership

Top ETFs holding this stock

This company is not held by any ETF in our universe.

Insider Activity

Insider Activity — Latest Quarter

No insider activity available.

Insider buys vs sells (history)

Insider history not available.

Recent insider transactions

No recent insider transactions.

Executive team

Top executives
EBIT / Employee
599.7K
Shares Outstanding
81.61M

Executive compensation

Executive compensation (annual)

Executive compensation not available.

CEO compensation breakdown

No CEO compensation history available.

Proxy statements

Proxy statements (DEF 14A)

No proxy statements available for this company yet.

Recent SEC filings

Recent SEC filings

No SEC filings available for this company yet.

Executive team

NameTitleCompensationGender
Artur Alexandrovich Isaev Founder, Chairman & Member of Scientific Advisory Board
Blokhina Svetlana Viktorovna Head of Corporate Department & Chairman of Audit Commission female
Bulanova Galina Igorevna Financial Director
Deev Roman Vadimovich Chief Scientific Officer, Director & Member of Scientific Advisory Board male
Dmitry Krasotkin Investment Director
Oksana Peterson Deputy Chief Accountant & Member of Audit Commission
Romanova Elena Anatolyevna Director of Public Relations female
Sergey Vladimirovich Masyuk General Director male
Zorin Vadim Leonidovich Head of Regenerative Medicine Department & Member of Scientific Advisory Board male
ESG Score History

No data available for this company.

Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend yield history

Dividend history

Earnings history

Earnings reports

Stock splits