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Werewolf Therapeutics, Inc. (HOWL)

USD0.34 0.00 (-1.34%)
US NASDAQ Healthcare Biotechnology
Address 1030 Massachusetts Avenue 2138
Watertown, MA, US
CEO Daniel J. Hicklin
IPO 2021-04-30
CIK 1785530 ISIN US95075A1079

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Description

Werewolf Therapeutics, Inc. is a biopharmaceutical firm dedicated to developing novel therapies that activate the body's immune system to combat cancer. Leveraging its exclusive PREDATOR platform, the company crafts conditionally activated molecules designed to stimulate both adaptive and innate immunity. This strategic approach aims to circumvent the shortcomings often associated with traditional proinflammatory immune treatments. Key among its product pipeline are WTX-124, a conditionally activated Interleukin-2 INDUKINE molecule targeting advanced solid tumors, and WTX-330, an Interleukin-12 INDUKINE molecule also designed for conditional activation, intended for advanced or metastatic solid tumors or lymphomas that have relapsed or are refractory. Furthermore, Werewolf Therapeutics is progressing WTX-613, a conditionally activated interferon alpha INDUKINE molecule, for addressing solid tumors and hematologic malignancies. The company was founded in 2017 and operates from its headquarters in Cambridge, Massachusetts.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
USD0.34 0.00 (-1.34%)
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Volume Profile
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Liquidity & share structure
Average Volume
640.1K
Beta
0.30
Float Shares
40.64M
Free Float %
83.6%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
-4.31% -5.25% -25.56% -4.10% -42.02% -0.24% -36.80% -78.50% -95.10% -96.07% -96.07%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
vs.
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Analyst Consensus (9 ratings, all time) Buy
Price Targets & DCF
Current price
0.34
Low 1.00 +194.6%
Consensus 1.00 +194.6%
Median 1.00 +194.6%
High 1.00 +194.6%
DCF (Unlevered) 1.02 +201.2%
DCF (Levered) 1.04 +205.3%

DCF figures are point estimates: small changes in growth or discount-rate assumptions move them materially. Read them as a reference, not a precise target.

Ratings Trend (MoM) 100% Bullish
Rating 2026-05 Change
Strong Buy 0 0
Buy 3 -1
Hold 0 0
Sell 0 0
Strong Sell 0 0
Price Target Summary
Period # Analysts Avg Target
Last Month
Last Quarter
Last Year 1
1.00
+194.6%
All Time 2
6.50
+1,814.6%
Quality scores
Altman Z-Score
-13.92
Distress
Piotroski F-Score
2 / 9
Weak
MOAT Score
2 / 10
No MOAT
Composite Rating
C+
Overall Score
2 / 5
Medium
DCF Score
4 / 5
High
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
1 / 5
Low
P/E Score
1 / 5
Low
P/Book Score
4 / 5
High
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
    -100.0%
  • EPS growth Biotechnology: +29.7%
    +18.4% Q1'26: +30.0% (vs Q1'25)
  • FCF margin FCF growth · Biotechnology: +16.2%
  • EBIT margin Biotechnology: +0.0%
  • ROIC Biotechnology: -16.1%
    Q1'26: -1,053.9% (vs Q1'25)
  • Share dilution Biotechnology: -3.4%
    +6.7% Q1'26: +10.2% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    -0.16× Q1'26: -1.10× (vs Q1'25)
Valuation Multiples From To
Price Forecast (3Y) From To
Model
Adjust
P/E
Theoretical Return — If Invested Today

* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.

DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (0.41) × ERP
WACC = 76% × Ke + 24% × Kd (55.9%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Intrinsic value (base): 1.02 Current price: 0.34
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2022
actual
Dec 2023
actual
Dec 2024
actual
Dec 2025
actual
Dec 2026
2 Rev. Ana.
2 EPS Ana.
Dec 2027
2 Rev. Ana.
1 EPS Ana.
Dec 2028
2 Rev. Ana.
2 EPS Ana.
Dec 2029
1 Rev. Ana.
1 EPS Ana.
Revenue
16.40M
est: 11.86M (+38.3%)
19.94M
est: 9.28M (+114.8%)
1.89M
est: 1.88M (+0.1%)
est: 2.52M (-100.0%)
8.33M
8.33M – 8.33M
+230.4% YoY
3.10M
3.10M – 3.10M
-62.8% YoY
50.0K
50.0K – 50.0K
-98.4% YoY
18.00M
18.00M – 18.00M
+35,900.0% YoY
EBITDA
-51.30M
est: -2.37M (-2,062.5%)
-32.47M
est: -1.86M (-1,648.6%)
-64.05M
est: -376.5K (-16,911.3%)
-59.04M
est: -504.5K (-11,603.6%)
-1.67M
-1.67M – -1.67M
-230.4% YoY
-620.0K
-620.0K – -620.0K
+62.8% YoY
-10.0K
-10.0K – -10.0K
+98.4% YoY
-3.60M
-3.60M – -3.60M
-35,903.6% YoY
EBIT
-53.81M
est: -2.37M (-2,168.3%)
-34.23M
est: -1.86M (-1,743.6%)
-65.86M
est: -376.5K (-17,393.2%)
-60.68M
est: -504.5K (-11,927.5%)
-1.67M
-1.67M – -1.67M
-230.4% YoY
-620.0K
-620.0K – -620.0K
+62.8% YoY
-10.0K
-10.0K – -10.0K
+98.4% YoY
-3.60M
-3.60M – -3.60M
-35,903.6% YoY
Net Income
-53.81M
est: -91.14M (+41.0%)
-37.37M
est: -63.93M (+41.5%)
-70.52M
est: -73.14M (+3.6%)
-60.82M
est: -70.21M (+13.4%)
-41.98M
-55.23M – -28.74M
+40.2% YoY
-74.43M
-102.66M – -46.20M
-77.3% YoY
-68.81M
-95.96M – -41.66M
+7.5% YoY
-46.11M
-46.11M – -46.11M
+33.0% YoY
SGA
21.50M
est: 34.04M (-36.8%)
18.67M
est: 26.64M (-29.9%)
19.05M
est: 5.40M (+252.5%)
15.85M
est: 7.24M (+118.9%)
23.92M
23.92M – 23.92M
+230.4% YoY
8.90M
8.90M – 8.90M
-62.8% YoY
143.5K
143.5K – 143.5K
-98.4% YoY
51.66M
51.66M – 51.66M
+35,900.2% YoY
EPS
-1.86
est: -2.08 (+10.5%)
-1.05
est: -1.37 (+23.1%)
-1.63
est: -1.50 (-8.9%)
-1.32
est: -1.51 (+12.3%)
-0.89
-1.18 – -0.61
+40.9% YoY
-1.60
-2.19 – -0.99
-79.2% YoY
-1.47
-2.05 – -0.89
+7.8% YoY
-0.99
-0.99 – -0.99
+33.0% YoY
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-12 C 2/5 4/5 1/5 1/5 1/5 1/5 2/5
2026-05-11 C 2/5 4/5 1/5 1/5 1/5 1/5 2/5
2026-05-08 C 2/5 4/5 1/5 1/5 1/5 1/5 2/5
2026-05-07 C+ 2/5 4/5 1/5 1/5 1/5 1/5 4/5
2026-05-06 C+ 2/5 4/5 1/5 1/5 1/5 1/5 4/5
2026-05-05 C+ 2/5 4/5 1/5 1/5 1/5 1/5 4/5
2026-05-04 C+ 2/5 4/5 1/5 1/5 1/5 1/5 4/5
2026-05-01 C+ 2/5 4/5 1/5 1/5 1/5 1/5 4/5
2026-04-30 C+ 2/5 4/5 1/5 1/5 1/5 1/5 4/5
2026-04-29 C+ 2/5 4/5 1/5 1/5 1/5 1/5 4/5
2026-04-28 C+ 2/5 4/5 1/5 1/5 1/5 1/5 4/5
2026-04-27 C+ 2/5 4/5 1/5 1/5 1/5 1/5 4/5
2026-04-24 C+ 2/5 4/5 1/5 1/5 1/5 1/5 4/5
2026-04-23 C+ 2/5 4/5 1/5 1/5 1/5 1/5 4/5
2026-04-22 C+ 2/5 4/5 1/5 1/5 1/5 1/5 4/5
2026-04-21 C+ 2/5 4/5 1/5 1/5 1/5 1/5 4/5
2026-04-20 C+ 2/5 4/5 1/5 1/5 1/5 1/5 4/5
2026-04-17 C+ 2/5 4/5 1/5 1/5 1/5 1/5 4/5
2026-04-16 C+ 2/5 4/5 1/5 1/5 1/5 1/5 4/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
-64.10M
OE per share TTM
-1.41
Owner's Yield
-214.23%
Maintenance CapEx ratio
Maint CapEx / Avg PPE
202.0%

Ownership Overview

Ownership breakdown
At a glance
Institutional holders
50
Total invested
9.34M
Insider transactions (90d)
6
Beneficial owners (>5%)
34
Beneficial owners (>5%)
# Reporting person Amount owned % of class Sole voting Shared voting Sole dispositive Shared dispositive Type Citizenship Filing date SEC filing
1 Ansbert Gadicke 6.73M 24.40% 6.73M 6.73M IN 2021-05-14
2 Luke Evnin 4.32M 15.70% 4.32M 4.32M IN 2021-05-14
3 Peter Kolchinsky 4.30M 14.57% 4.30M 10.00 HC, IN United States 2022-08-12
4 RA Capital Management, L.P. 4.30M 14.57% 4.30M 10.00 IA, PN Delaware 2022-08-12
5 Rajeev Shah 4.30M 14.57% 4.30M 10.00 HC, IN United States 2022-08-12
6 RA Capital Healthcare Fund, L.P. 3.86M 13.07% 3.86M 10.00 PN United States 2022-08-12
7 MPM BioVentures 2014 LLC 3.21M 11.70% 3.21M 3.21M OO 2021-05-14
8 Todd Foley 3.21M 11.70% 3.21M 3.21M IN 2021-05-14
9 MPM BioVentures 2014 GP LLC 3.11M 11.30% 3.11M 3.11M OO 2021-05-14
10 Adage Capital Management, L.P. 3.03M 8.38% 3.03M IA, PN Delaware 2023-12-21
11 Adage Capital Partners GP, L.L.C. 3.03M 8.38% 3.03M OO Delaware 2023-12-21
12 Adage Capital Partners, L.P. 3.03M 8.38% 3.03M PN Delaware 2023-12-21
13 Phillip Gross 3.03M 8.38% 3.03M IN United States 2023-12-21
14 Robert Atchinson 3.03M 8.38% 3.03M IN United States 2023-12-21
15 MPM Oncology Impact Management GP LLC 2.41M 8.80% 2.41M 2.41M OO 2021-05-14
16 MPM Oncology Impact Management LP 2.41M 8.80% 2.41M 2.41M PN 2021-05-14
17 Oncology Impact Fund (Cayman) Management LP 2.41M 8.80% 2.41M 2.41M PN 2021-05-14
18 UBS Oncology Impact Fund, L.P. 2.41M 8.80% 2.41M 2.41M PN 2021-05-14
19 BANK OF AMERICA CORPORATION56-0906609 2.10M 5.80% 2.08M 2.10M HC 2024-02-13
20 Taiho Ventures LLC 2.07M 7.51% 2.07M 2.07M CO 2021-05-13
21 David Rosen 1.84M 5.97% 1.84M IN United States of America 2023-02-10
22 LP 1.84M 5.97% 1.84M IA, PN State of Delaware 2023-02-10
23 Longwood Fund III GP, LLC 1.68M 6.10% 1.68M 1.68M OO Delaware 2021-05-14
24 Longwood Fund III, L.P. 1.68M 6.10% 1.68M 1.68M PN Delaware 2021-05-14
25 Company, L.P. 958.1K 3.47% 958.1K PN Delaware 2022-02-11
26 Deerfield Mgmt, L.P. 958.1K 3.47% 958.1K PN Delaware 2022-02-11
27 Deerfield Partners, L.P. 958.1K 3.47% 958.1K PN Delaware 2022-02-11
28 James E. Flynn 958.1K 3.47% 958.1K IN Delaware 2022-02-11
29 MPM Oncology Innovations Fund GP LLC 640.1K 2.30% 640.1K 640.1K OO 2021-05-14
30 MPM Oncology Innovations Fund, L.P. 640.1K 2.30% 640.1K 640.1K PN 2021-05-14
31 Stephen Curtis 640.1K 2.30% 640.1K 640.1K IN 2021-05-14
32 MPM Asset Management LLC 461.4K 1.70% 461.4K 461.4K OO 2021-05-14
33 MPM BioVentures 2014 (B), L.P. 194.7K 0.70% 194.7K 194.7K PN 2021-05-14
34 MPM Asset Management Investors BV2014 LLC 100.5K 0.40% 100.5K 100.5K OO 2021-05-14

Institutional Activity (13F)

Institutional ownership trend From To
13F snapshot — 2025 Q4
Investors holding
50
-12 vs prev Q
New positions
7
Closed positions
19
Increased
21
Reduced
16
Put/Call ratio
0.00
Calls held
Puts held
Top institutional holders
# Investor Shares / Δ Mkt value / Δ Own% / Δ Weight% / Δ Avg px / Perf. Hold / Status
1 RA CAPITAL MANAGEMENT, L.P. 6.68M +— (+0.0%) 4.23M -8.9M (-67.8%) 14.69% -0.160 pp 0.04% -0.119 pp USD12.01 -94.8% 19 qtrs
2 VANGUARD GROUP INC 1.41M +— (+0.0%) 892.7K -1.9M (-67.8%) 3.10% -0.034 pp 0.00% +0.000 pp USD5.89 -89.3% 19 qtrs
3 BIOIMPACT CAPITAL LLC 1.39M -1.0M (-42.1%) 883.5K -3.9M (-81.4%) 3.06% -2.291 pp 0.10% -0.676 pp USD17.30 -96.4% 19 qtrs
4 BANK OF AMERICA CORP /DE/ 737.6K -1.1M (-59.7%) 466.9K -3.1M (-87.1%) 1.62% -2.447 pp 0.00% 0.000 pp USD2.49 -74.7% 19 qtrs
5 RENAISSANCE TECHNOLOGIES LLC 677.8K +221.8K (+48.6%) 429.4K -469.0K (-52.2%) 1.49% +0.477 pp 0.00% -0.001 pp USD1.27 -50.4% 15 qtrs
6 LYNX1 CAPITAL MANAGEMENT LP 655.9K +655.9K (+100.0%) 415.5K +415.5K (+100.0%) 1.44% +1.443 pp 0.08% +0.084 pp USD0.63 +0.0% 1 qtrs NEW
7 SPHERA FUNDS MANAGEMENT LTD. 626.8K +— (+0.0%) 397.1K -837.7K (-67.8%) 1.38% -0.015 pp 0.08% -0.184 pp USD16.55 -96.2% 19 qtrs
8 DC FUNDS, LP 589.1K +— (+0.0%) 373.2K -787.3K (-67.8%) 1.30% -0.014 pp 25.69% -11.630 pp USD17.26 -96.3% 19 qtrs
9 GEODE CAPITAL MANAGEMENT, LLC 335.9K +5.1K (+1.5%) 212.8K -439.0K (-67.3%) 0.74% +0.003 pp 0.00% +0.000 pp USD3.91 -83.9% 19 qtrs
10 MILLENNIUM MANAGEMENT LLC 240.1K -76.9K (-24.3%) 152.1K -472.5K (-75.6%) 0.53% -0.177 pp 0.00% 0.000 pp USD2.50 -74.8% 16 qtrs
11 ALYESKA INVESTMENT GROUP, L.P. 235.7K +— (+0.0%) 149.3K -315.0K (-67.8%) 0.52% -0.006 pp 0.00% -0.001 pp USD9.73 -93.5% 19 qtrs
12 JANE STREET GROUP, LLC 157.3K -111.3K (-41.4%) 99.7K -429.4K (-81.2%) 0.35% -0.251 pp 0.00% 0.000 pp USD1.09 -42.2% 9 qtrs
13 STATE STREET CORP 119.2K +— (+0.0%) 75.5K -159.3K (-67.8%) 0.26% -0.003 pp 0.00% +0.000 pp USD2.77 -77.3% 19 qtrs
14 BLACKROCK, INC. 101.6K +320.0 (+0.3%) 64.4K -135.2K (-67.7%) 0.22% -0.002 pp 0.00% +0.000 pp USD2.09 -69.9% 6 qtrs
15 SUSQUEHANNA INTERNATIONAL GROUP, LLP 99.8K +6.8K (+7.3%) 63.2K -120.0K (-65.5%) 0.22% +0.013 pp 0.00% +0.000 pp USD1.29 -51.2% 5 qtrs
16 NORTHERN TRUST CORP 86.9K +21.0K (+31.9%) 55.0K -74.7K (-57.6%) 0.19% +0.045 pp 0.00% +0.000 pp USD2.32 -72.8% 19 qtrs
17 BRIDGEWAY CAPITAL MANAGEMENT, LLC 77.0K -25.0K (-24.5%) 48.8K -152.2K (-75.7%) 0.17% -0.057 pp 0.00% -0.003 pp USD1.65 -61.8% 15 qtrs
18 UBS GROUP AG 60.7K +47.9K (+375.2%) 38.4K +13.3K (+52.7%) 0.13% +0.105 pp 0.00% +0.000 pp USD0.91 -30.8% 19 qtrs
19 VONTOBEL HOLDING LTD. 60.0K +24.0K (+66.7%) 38.0K -32.9K (-46.4%) 0.13% +0.052 pp 0.00% 0.000 pp USD0.85 -25.9% 4 qtrs
20 REGAL INVESTMENT ADVISORS LLC 52.6K +25.4K (+93.3%) 33.3K -20.3K (-37.8%) 0.12% +0.055 pp 0.00% -0.002 pp USD1.25 -49.6% 6 qtrs
21 EDGEWOOD MANAGEMENT LLC 50.0K +— (+0.0%) 31.7K -66.8K (-67.8%) 0.11% -0.001 pp 0.00% 0.000 pp USD2.60 -75.8% 12 qtrs
22 MORGAN STANLEY 46.0K +26.8K (+138.9%) 29.1K -8.8K (-23.2%) 0.10% +0.058 pp 0.00% +0.000 pp USD1.51 -58.3% 19 qtrs
23 GOLDMAN SACHS GROUP INC 34.1K -26.3K (-43.5%) 21.6K -97.3K (-81.8%) 0.07% -0.059 pp 0.00% +0.000 pp USD2.31 -72.7% 8 qtrs
24 SIMPLEX TRADING, LLC 24.1K +8.4K (+53.8%) 15.3K -14.8K (-49.2%) 0.05% +0.018 pp 0.00% +0.000 pp USD1.31 -51.9% 11 qtrs
25 CERTUITY, LLC 15.0K +— (+0.0%) 9.5K -20.0K (-67.8%) 0.03% 0.000 pp 0.00% -0.001 pp USD3.28 -80.8% 9 qtrs
26 DELTA INVESTMENT MANAGEMENT, LLC 14.9K +14.9K (+100.0%) 9.5K +9.5K (+100.0%) 0.03% +0.033 pp 0.00% +0.002 pp USD0.63 +0.0% 1 qtrs NEW
27 POINT72 ASSET MANAGEMENT, L.P. 14.5K +14.5K (+100.0%) 9.2K +9.2K (+100.0%) 0.03% +0.032 pp 0.00% +0.000 pp USD0.63 +0.0% 1 qtrs NEW
28 BARCLAYS PLC 13.2K -41.6K (-75.9%) 8.4K -107.8K (-92.8%) 0.03% -0.093 pp 0.00% +0.000 pp USD2.05 -69.3% 8 qtrs
29 LARSON FINANCIAL GROUP LLC 13.1K +3.1K (+30.5%) 8.3K -11.4K (-58.0%) 0.03% +0.007 pp 0.00% 0.000 pp USD1.28 -50.8% 5 qtrs
30 HBK SORCE ADVISORY LLC 13.2K +— (+0.0%) 8.1K -15.2K (-65.2%) 0.03% 0.000 pp 0.00% 0.000 pp USD2.46 -74.4% 12 qtrs
31 ENGINEERS GATE MANAGER LP 12.2K +12.2K (+100.0%) 7.7K +7.7K (+100.0%) 0.03% +0.027 pp 0.00% +0.000 pp USD0.63 +0.0% 1 qtrs NEW
32 HIGHLINE WEALTH PARTNERS LLC 12.0K +7.0K (+140.0%) 7.6K -2.2K (-22.8%) 0.03% +0.015 pp 0.00% -0.001 pp USD0.82 -23.2% 3 qtrs
33 RANCH CAPITAL ADVISORS INC. 12.0K +12.0K (+100.0%) 7.6K +7.6K (+100.0%) 0.03% +0.026 pp 0.00% +0.003 pp USD0.63 +0.0% 1 qtrs NEW
34 STONEX GROUP INC. 10.5K +10.5K (+100.0%) 6.7K +6.7K (+100.0%) 0.02% +0.023 pp 0.00% +0.000 pp USD0.63 +0.0% 1 qtrs NEW
35 TWO SIGMA ADVISERS, LP 10.3K -24.3K (-70.2%) 6.5K -61.6K (-90.4%) 0.02% -0.054 pp 0.00% 0.000 pp USD4.41 -85.7% 9 qtrs
36 CETERA INVESTMENT ADVISERS 10.2K +— (+0.0%) 6.5K -13.6K (-67.8%) 0.02% 0.000 pp 0.00% +0.000 pp USD1.97 -68.0% 2 qtrs
37 ADVISOR GROUP HOLDINGS, INC. 8.6K -1.0K (-10.4%) 5.4K -7.9K (-59.1%) 0.02% -0.002 pp 0.00% +0.000 pp USD1.42 -55.6% 5 qtrs
38 FINANCIAL PERSPECTIVES, INC 6.8K +— (+0.0%) 4.3K -9.0K (-67.8%) 0.01% 0.000 pp 0.00% -0.003 pp USD3.54 -82.2% 19 qtrs
39 TFC FINANCIAL MANAGEMENT, INC. 4.5K +2.0K (+80.0%) 2.9K -2.1K (-42.1%) 0.01% +0.004 pp 0.00% 0.000 pp USD1.39 -54.7% 7 qtrs
40 FEDERATED HERMES, INC. 4.4K +— (+0.0%) 2.8K -5.9K (-67.8%) 0.01% 0.000 pp 0.00% +0.000 pp USD1.01 -37.6% 5 qtrs
41 FMR LLC 3.6K -7.7K (-67.8%) 2.3K -19.9K (-89.7%) 0.01% -0.017 pp 0.00% +0.000 pp USD1.21 -47.9% 7 qtrs
42 JPMORGAN CHASE & CO 2.1K +949.0 (+84.5%) 1.3K -899.0 (-40.6%) 0.00% +0.002 pp 0.00% +0.000 pp USD1.65 -61.8% 19 qtrs
43 GROUP ONE TRADING, L.P. 1.9K -800.0 (-30.0%) 1.2K -4.1K (-77.5%) 0.00% -0.002 pp 0.00% +0.000 pp USD1.97 -68.0% 2 qtrs
44 BNP PARIBAS ARBITRAGE, SNC 792.00 -1.0 (-0.1%) 502.00 -1.1K (-67.9%) 0.00% +0.000 pp 0.00% +0.000 pp USD1.45 -56.6% 5 qtrs
45 NISA INVESTMENT ADVISORS, LLC 345.00 -1.0K (-74.9%) 219.00 -2.5K (-91.9%) 0.00% -0.002 pp 0.00% +0.000 pp USD1.09 -42.2% 6 qtrs
46 SRS CAPITAL ADVISORS, INC. 39.00 -29.0 (-42.6%) 25.00 -108.0 (-81.2%) 0.00% 0.000 pp 0.00% +0.000 pp USD1.95 -67.7% 2 qtrs
47 SBI SECURITIES CO., LTD. 40.00 -1.0 (-2.4%) 25.00 -56.0 (-69.1%) 0.00% +0.000 pp 0.00% +0.000 pp USD1.45 -56.6% 5 qtrs
48 OPTIVER HOLDING B.V. 22.00 +— (+0.0%) 14.00 -29.0 (-67.4%) 0.00% +0.000 pp 0.00% +0.000 pp USD1.95 -67.7% 2 qtrs
49 NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO 4.00 +4.0 (+100.0%) 3.00 +3.0 (+100.0%) 0.00% +0.000 pp 0.00% +0.000 pp USD0.50 +26.0% 1 qtrs NEW
50 CITIGROUP INC 1.00 -8.7K (-100.0%) 1.00 -17.1K (-100.0%) 0.00% -0.019 pp 0.00% +0.000 pp USD2.00 -68.5% 8 qtrs
51 ACADIAN ASSET MANAGEMENT LLC -34.3K (-100.0%) -67.0K (-100.0%) 0.00% -0.076 pp 0.00% 0.000 pp USD 13 qtrs SOLD
52 CITADEL ADVISORS LLC -154.5K (-100.0%) -304.4K (-100.0%) 0.00% -0.344 pp 0.00% +0.000 pp USD 2 qtrs SOLD
53 PFM HEALTH SCIENCES, LP -401.1K (-100.0%) -790.2K (-100.0%) 0.00% -0.892 pp 0.00% -0.061 pp USD 19 qtrs SOLD
54 PLANTE MORAN FINANCIAL ADVISORS, LLC -50.0 (-100.0%) -99.0 (-100.0%) 0.00% 0.000 pp 0.00% +0.000 pp USD 3 qtrs SOLD
55 EVERSOURCE WEALTH ADVISORS, LLC -35.0 (-100.0%) -69.0 (-100.0%) 0.00% 0.000 pp 0.00% +0.000 pp USD 5 qtrs SOLD
56 QUBE RESEARCH & TECHNOLOGIES LTD -29.3K (-100.0%) -57.6K (-100.0%) 0.00% -0.065 pp 0.00% 0.000 pp USD 3 qtrs SOLD
57 AQR CAPITAL MANAGEMENT LLC -17.8K (-100.0%) -35.1K (-100.0%) 0.00% -0.040 pp 0.00% +0.000 pp USD 4 qtrs SOLD
58 TOWER RESEARCH CAPITAL LLC (TRC) -6.0K (-100.0%) -11.8K (-100.0%) 0.00% -0.013 pp 0.00% 0.000 pp USD 19 qtrs SOLD
59 CWM, LLC -1.6K (-100.0%) -3.0K (-100.0%) 0.00% -0.004 pp 0.00% +0.000 pp USD 4 qtrs SOLD
60 TWO SIGMA INVESTMENTS, LP -20.1K (-100.0%) -39.7K (-100.0%) 0.00% -0.045 pp 0.00% 0.000 pp USD 13 qtrs SOLD
61 ADVISORY SERVICES NETWORK, LLC -157.0 (-100.0%) -309.0 (-100.0%) 0.00% 0.000 pp 0.00% +0.000 pp USD 2 qtrs SOLD
62 HRT FINANCIAL LP -39.9K (-100.0%) -78.0K (-100.0%) 0.00% -0.089 pp 0.00% 0.000 pp USD 3 qtrs SOLD
63 VIRTU FINANCIAL LLC -12.2K (-100.0%) -24.0K (-100.0%) 0.00% -0.027 pp 0.00% -0.001 pp USD 2 qtrs SOLD
64 RAYMOND JAMES FINANCIAL INC -14.4K (-100.0%) -28.4K (-100.0%) 0.00% -0.032 pp 0.00% +0.000 pp USD 3 qtrs SOLD
65 ROSSBY FINANCIAL, LCC -860.0 (-100.0%) -1.7K (-100.0%) 0.00% -0.002 pp 0.00% -0.001 pp USD 4 qtrs SOLD
66 ROYAL BANK OF CANADA -806.0 (-100.0%) -1.0K (-100.0%) 0.00% -0.002 pp 0.00% +0.000 pp USD 7 qtrs SOLD
Ownership breakdown by holder

ETF Ownership

Top ETFs holding this stock Held by 11 ETFs in our universe
# ETF Weight Est. AUM exposure TER
1 Vanguard Extended Market ETF VXF 0.00% 151.4K 0.05%
2 Vanguard U.S. Total Market Shares Index ETF VTS.AX 0.00% 833.17 0.03%
3 Vanguard U.S. Total Market Index ETF VUN.TO 0.00% 2.3K 0.17%
4 Vanguard U.S. Total Market Index ETF (CAD-hedged) VUS.TO 0.00% 168.97 0.17%
5 Vanguard Total Stock Market ETF VTI 0.00% 391.0K 0.03%
6 Vanguard All-Equity ETF Portfolio VEQT.TO 0.00% 857.28 0.22%
7 Vanguard Growth ETF Portfolio VGRO.TO 0.00% 466.73 0.22%
8 Vanguard Balanced ETF Portfolio VBAL.TO 0.00% 188.37 0.22%
9 Vanguard Conservative ETF Portfolio VCNS.TO 0.00% 20.79 0.22%
10 Vanguard Conservative Income ETF Portfolio VCIP.TO 0.00% 2.93 0.22%

Insider Activity

Insider Activity — Latest Quarter
Ratio by transactions
0.00
Bearish
Ratio by volume
0.00
Bearish
Buys
0
Sells
6
Shares acquired
Shares disposed
480.5K
Cash buys
Cash sales
6.00
Net activity
-480,530
Insider buys vs sells (history) From To
Recent insider transactions From To
Date Person Role Transaction A/D Security Shares Price Value Owned after D/I Filing
2026-05-04 EVNIN LUKE Director S-Sale D Common Stock 47,963 0.72 34.5K 1,679,330 I
2026-05-01 EVNIN LUKE Director S-Sale D Common Stock 58,394 0.73 42.6K 1,727,293 I
2026-04-30 EVNIN LUKE Director S-Sale D Common Stock 168,262 0.72 121.1K 1,785,687 I
2026-04-29 EVNIN LUKE Director S-Sale D Common Stock 56,559 0.69 39.0K 1,953,949 I
2026-04-28 EVNIN LUKE Director S-Sale D Common Stock 95,412 0.73 69.7K 2,010,508 I
2026-04-27 EVNIN LUKE Director S-Sale D Common Stock 53,940 0.85 45.8K 2,105,920 I
2026-02-13 Urban Michael J. Officer Stock Option (right to buy) 10,000 1.57 15.7K 0 D
2026-01-16 EVNIN LUKE Director S-Sale D Common Stock 38,782 0.54 20.9K 2,159,860 I
2026-01-15 EVNIN LUKE Director S-Sale D Common Stock 37,413 0.55 20.6K 2,198,642 I
2026-01-14 EVNIN LUKE Director S-Sale D Common Stock 30,616 0.57 17.5K 2,236,055 I
2026-01-13 EVNIN LUKE Director S-Sale D Common Stock 43,198 0.55 23.8K 2,266,671 I
2026-01-12 EVNIN LUKE Director S-Sale D Common Stock 58,980 0.57 33.6K 2,309,869 I
2026-01-09 EVNIN LUKE Director S-Sale D Common Stock 24,678 0.61 15.1K 2,368,849 I
2026-01-08 EVNIN LUKE Director S-Sale D Common Stock 7,716 0.63 4.9K 2,393,527 I
2026-01-07 EVNIN LUKE Director S-Sale D Common Stock 11,915 0.64 7.6K 2,401,243 I
2026-01-06 EVNIN LUKE Director S-Sale D Common Stock 40,761 0.65 26.5K 2,413,158 I
2026-01-05 EVNIN LUKE Director S-Sale D Common Stock 18,378 0.64 11.8K 2,453,919 I
2026-01-02 EVNIN LUKE Director S-Sale D Common Stock 18,568 0.63 11.7K 2,472,297 I
2025-12-31 EVNIN LUKE Director S-Sale D Common Stock 24,962 0.62 15.5K 2,490,865 I
2025-12-30 EVNIN LUKE Director S-Sale D Common Stock 34,847 0.61 21.3K 2,515,827 I
2025-12-29 EVNIN LUKE Director S-Sale D Common Stock 108,606 0.61 66.2K 2,550,674 I
2025-12-26 EVNIN LUKE Director S-Sale D Common Stock 35,632 0.63 22.4K 2,659,280 I
2025-12-24 EVNIN LUKE Director S-Sale D Common Stock 16,310 0.65 10.6K 2,694,912 I
2025-12-23 EVNIN LUKE Director S-Sale D Common Stock 71,428 0.63 45.0K 2,711,222 I
2025-12-22 EVNIN LUKE Director S-Sale D Common Stock 59,307 0.69 40.9K 2,782,650 I
2025-12-17 EVNIN LUKE Director S-Sale D Common Stock 9,983 1.14 11.4K 2,841,957 I
2025-12-16 EVNIN LUKE Director S-Sale D Common Stock 14,548 1.05 15.3K 2,851,940 I
2025-12-15 EVNIN LUKE Director S-Sale D Common Stock 23,640 1.07 25.3K 2,866,488 I
2025-12-12 EVNIN LUKE Director S-Sale D Common Stock 17,858 1.08 19.3K 2,890,128 I
2025-12-11 EVNIN LUKE Director S-Sale D Common Stock 28,009 1.07 30.0K 2,907,986 I
2025-12-10 EVNIN LUKE Director S-Sale D Common Stock 37,104 1.06 39.3K 2,935,995 I
2025-12-09 EVNIN LUKE Director S-Sale D Common Stock 44,570 1.01 45.0K 2,973,099 I
2025-12-08 EVNIN LUKE Director S-Sale D Common Stock 34,041 0.99 33.7K 3,017,669 I
2025-12-05 EVNIN LUKE Director S-Sale D Common Stock 16,568 0.97 16.1K 3,051,710 I
2025-12-04 MPM BioVentures 2014, L.P. 10% Owner S-Sale D Common Stock 83,230 0.97 80.7K 4,784,111 I
2025-12-04 GADICKE ANSBERT 10% Owner S-Sale D Common Stock 83,230 0.97 80.7K 4,784,111 I
2025-12-04 EVNIN LUKE Director S-Sale D Common Stock 53,416 0.97 51.8K 3,068,278 I
2025-12-03 MPM BioVentures 2014, L.P. 10% Owner S-Sale D Common Stock 57,225 0.87 49.8K 4,867,341 I
2025-12-03 GADICKE ANSBERT 10% Owner S-Sale D Common Stock 57,225 0.87 49.8K 4,867,341 I
2025-12-03 EVNIN LUKE Director S-Sale D Common Stock 36,726 0.87 32.0K 3,121,694 I
2025-12-02 MPM BioVentures 2014, L.P. 10% Owner S-Sale D Common Stock 59,277 0.89 52.8K 4,924,566 I
2025-12-02 GADICKE ANSBERT 10% Owner S-Sale D Common Stock 59,277 0.89 52.8K 4,924,566 I
2025-12-02 EVNIN LUKE Director S-Sale D Common Stock 38,043 0.89 33.9K 3,158,420 I
2025-12-01 MPM BioVentures 2014, L.P. 10% Owner S-Sale D Common Stock 60,917 0.94 57.3K 4,983,843 I
2025-12-01 GADICKE ANSBERT 10% Owner S-Sale D Common Stock 60,917 0.94 57.3K 4,983,843 I
2025-12-01 EVNIN LUKE Director S-Sale D Common Stock 39,096 0.94 36.8K 3,196,463 I
2025-11-28 MPM BioVentures 2014, L.P. 10% Owner S-Sale D Common Stock 20,277 0.99 20.1K 5,044,760 I
2025-11-28 GADICKE ANSBERT 10% Owner S-Sale D Common Stock 20,277 0.99 20.1K 5,044,760 I
2025-11-28 EVNIN LUKE Director S-Sale D Common Stock 13,014 0.99 12.9K 3,235,559 I
2025-11-26 MPM BioVentures 2014, L.P. 10% Owner S-Sale D Common Stock 60,733 0.98 59.5K 5,065,037 I
2025-11-26 GADICKE ANSBERT 10% Owner S-Sale D Common Stock 60,733 0.98 59.5K 5,065,037 I
2025-11-26 EVNIN LUKE Director S-Sale D Common Stock 38,978 0.98 38.2K 3,248,573 I
2025-11-25 MPM BioVentures 2014, L.P. 10% Owner S-Sale D Common Stock 42,533 0.92 39.1K 5,125,770 I
2025-11-25 GADICKE ANSBERT 10% Owner S-Sale D Common Stock 42,533 0.92 39.1K 5,125,770 I
2025-11-25 EVNIN LUKE Director S-Sale D Common Stock 27,297 0.92 25.1K 3,287,551 I
2025-11-24 MPM BioVentures 2014, L.P. 10% Owner S-Sale D Common Stock 88,802 0.98 87.0K 5,168,303 I
2025-11-24 GADICKE ANSBERT 10% Owner S-Sale D Common Stock 88,802 0.98 87.0K 5,168,303 I
2025-11-24 EVNIN LUKE Director S-Sale D Common Stock 56,992 0.98 55.9K 3,314,848 I
2025-11-21 MPM BioVentures 2014, L.P. 10% Owner S-Sale D Common Stock 64,331 0.83 53.4K 5,257,105 I
2025-11-21 GADICKE ANSBERT 10% Owner S-Sale D Common Stock 64,331 0.83 53.4K 5,257,105 I
2025-11-21 EVNIN LUKE Director S-Sale D Common Stock 41,287 0.83 34.3K 3,371,840 I
2025-11-20 MPM BioVentures 2014, L.P. 10% Owner S-Sale D Common Stock 41,152 0.89 36.6K 5,321,436 I
2025-11-20 GADICKE ANSBERT 10% Owner S-Sale D Common Stock 41,152 0.89 36.6K 5,321,436 I
2025-11-20 EVNIN LUKE Director S-Sale D Common Stock 26,411 0.89 23.5K 3,413,127 I
2025-11-19 MPM BioVentures 2014, L.P. 10% Owner S-Sale D Common Stock 66,324 0.94 62.3K 5,362,588 I
2025-11-19 GADICKE ANSBERT 10% Owner S-Sale D Common Stock 66,324 0.94 62.3K 5,362,588 I
2025-11-19 EVNIN LUKE Director S-Sale D Common Stock 42,566 0.94 40.0K 3,439,538 I
2025-11-18 MPM BioVentures 2014, L.P. 10% Owner S-Sale D Common Stock 52,627 0.93 48.9K 5,428,912 I
2025-11-18 GADICKE ANSBERT 10% Owner S-Sale D Common Stock 52,627 0.93 48.9K 5,428,912 I
2025-11-18 EVNIN LUKE Director S-Sale D Common Stock 33,776 0.93 31.4K 3,482,104 I
2025-11-17 MPM BioVentures 2014, L.P. 10% Owner S-Sale D Common Stock 57,061 0.95 54.2K 5,481,539 I
2025-11-17 GADICKE ANSBERT 10% Owner S-Sale D Common Stock 57,061 0.95 54.2K 5,481,539 I
2025-11-17 EVNIN LUKE Director S-Sale D Common Stock 36,621 0.95 34.8K 3,515,880 I
2025-11-14 MPM BioVentures 2014, L.P. 10% Owner S-Sale D Common Stock 61,640 0.93 57.3K 5,538,600 I
2025-11-14 GADICKE ANSBERT 10% Owner S-Sale D Common Stock 61,640 0.93 57.3K 5,538,600 I
2025-11-14 EVNIN LUKE Director S-Sale D Common Stock 39,560 0.93 36.8K 3,552,501 I
2025-11-13 MPM BioVentures 2014, L.P. 10% Owner S-Sale D Common Stock 90,951 0.98 89.1K 5,600,240 I
2025-11-13 GADICKE ANSBERT 10% Owner S-Sale D Common Stock 90,951 0.98 89.1K 5,600,240 I
2025-11-13 EVNIN LUKE Director S-Sale D Common Stock 58,372 0.98 57.2K 3,592,061 I
2025-11-12 MPM BioVentures 2014, L.P. 10% Owner S-Sale D Common Stock 40,669 1.09 44.3K 5,691,191 I
2025-11-12 GADICKE ANSBERT 10% Owner S-Sale D Common Stock 40,669 1.09 44.3K 5,691,191 I
2025-11-12 EVNIN LUKE Director S-Sale D Common Stock 26,101 1.09 28.5K 3,650,433 I
2025-11-11 MPM BioVentures 2014, L.P. 10% Owner S-Sale D Common Stock 55,810 1.14 63.6K 5,731,860 I
2025-11-11 GADICKE ANSBERT 10% Owner S-Sale D Common Stock 55,810 1.14 63.6K 5,731,860 I
2025-11-11 EVNIN LUKE Director S-Sale D Common Stock 35,818 1.14 40.8K 3,676,534 I
2025-11-10 MPM BioVentures 2014, L.P. 10% Owner S-Sale D Common Stock 48,570 1.18 57.3K 5,787,670 I
2025-11-10 GADICKE ANSBERT 10% Owner S-Sale D Common Stock 48,570 1.18 57.3K 5,787,670 I
2025-11-10 EVNIN LUKE Director S-Sale D Common Stock 31,172 1.18 36.8K 3,712,352 I
2025-11-07 MPM BioVentures 2014, L.P. 10% Owner S-Sale D Common Stock 68,480 1.11 76.0K 5,836,240 I
2025-11-07 GADICKE ANSBERT 10% Owner S-Sale D Common Stock 68,480 1.11 76.0K 5,836,240 I
2025-11-07 EVNIN LUKE Director S-Sale D Common Stock 43,950 1.11 48.8K 3,743,524 I
2025-11-06 MPM BioVentures 2014, L.P. 10% Owner S-Sale D Common Stock 54,452 1.21 65.9K 5,904,720 I
2025-11-06 GADICKE ANSBERT 10% Owner S-Sale D Common Stock 54,452 1.21 65.9K 5,904,720 I
2025-11-06 EVNIN LUKE Director S-Sale D Common Stock 34,947 1.21 42.3K 3,787,474 I
2025-11-05 MPM BioVentures 2014, L.P. 10% Owner S-Sale D Common Stock 47,950 1.22 58.5K 5,959,172 I
2025-11-05 GADICKE ANSBERT 10% Owner S-Sale D Common Stock 47,950 1.22 58.5K 5,959,172 I
2025-11-05 EVNIN LUKE Director S-Sale D Common Stock 30,774 1.22 37.5K 3,822,421 I
2025-11-04 MPM BioVentures 2014, L.P. 10% Owner S-Sale D Common Stock 140,488 1.22 171.4K 6,007,122 I
2025-11-04 GADICKE ANSBERT 10% Owner S-Sale D Common Stock 140,488 1.22 171.4K 6,007,122 I
2025-11-04 EVNIN LUKE Director S-Sale D Common Stock 90,164 1.22 110.0K 3,853,195 I
2025-11-03 MPM BioVentures 2014, L.P. 10% Owner S-Sale D Common Stock 94,063 1.29 121.3K 6,147,610 I
2025-11-03 GADICKE ANSBERT 10% Owner S-Sale D Common Stock 94,063 1.29 121.3K 6,147,610 I
2025-11-03 EVNIN LUKE Director S-Sale D Common Stock 60,369 1.29 77.9K 3,943,359 I
2025-10-31 MPM BioVentures 2014, L.P. 10% Owner S-Sale D Common Stock 114,044 1.28 146.0K 6,241,673 I
2025-10-31 GADICKE ANSBERT 10% Owner S-Sale D Common Stock 114,044 1.28 146.0K 6,241,673 I
2025-10-31 EVNIN LUKE Director S-Sale D Common Stock 73,192 1.28 93.7K 4,003,728 I
2025-10-30 MPM BioVentures 2014, L.P. 10% Owner S-Sale D Common Stock 86,936 1.43 124.3K 6,355,717 I
2025-10-30 GADICKE ANSBERT 10% Owner S-Sale D Common Stock 86,936 1.43 124.3K 6,355,717 I
2025-10-30 EVNIN LUKE Director S-Sale D Common Stock 55,795 1.43 79.8K 4,076,920 I
2025-10-29 MPM BioVentures 2014, L.P. 10% Owner S-Sale D Common Stock 134,240 1.55 208.1K 6,442,653 I
2025-10-29 GADICKE ANSBERT 10% Owner S-Sale D Common Stock 134,240 1.55 208.1K 6,442,653 I
2025-10-29 EVNIN LUKE Director S-Sale D Common Stock 86,154 1.55 133.5K 4,132,715 I
2025-10-28 MPM BioVentures 2014, L.P. 10% Owner S-Sale D Common Stock 69,068 1.64 113.3K 6,576,893 I
2025-10-28 GADICKE ANSBERT 10% Owner S-Sale D Common Stock 69,068 1.64 113.3K 6,576,893 I
2025-10-28 EVNIN LUKE Director S-Sale D Common Stock 44,327 1.64 72.7K 4,218,869 I
2025-10-27 MPM BioVentures 2014, L.P. 10% Owner S-Sale D Common Stock 72,709 1.72 125.1K 6,645,961 I
2025-10-27 GADICKE ANSBERT 10% Owner S-Sale D Common Stock 72,709 1.72 125.1K 6,645,961 I
2025-10-27 EVNIN LUKE Director S-Sale D Common Stock 46,664 1.72 80.3K 4,263,196 I
2025-06-12 Singhal Anil K. Director A-Award A Stock Option (right to buy) 8,358 1.29 10.8K 8,358 D
2025-06-12 Sherman Michael A. Director A-Award A Stock Option (right to buy) 27,000 1.29 34.8K 27,000 D
2025-06-12 Morrison Briggs Director A-Award A Stock Option (right to buy) 27,000 1.29 34.8K 27,000 D
2025-06-12 Lazarus Alon Director A-Award A Stock Option (right to buy) 27,000 1.29 34.8K 27,000 D
2025-06-12 EVNIN LUKE Director A-Award A Stock Option (right to buy) 27,000 1.29 34.8K 27,000 D
2025-06-12 Chatterjee Meeta Director A-Award A Stock Option (right to buy) 27,000 1.29 34.8K 27,000 D
2025-06-12 Atkins Michael B. Director A-Award A Stock Option (right to buy) 27,000 1.29 34.8K 27,000 D
2025-06-11 Singhal Anil K. Director A-Award A Stock Option (right to buy) 9,000 1.23 11.1K 9,000 D
2025-05-14 RA CAPITAL MANAGEMENT, L.P. Director / 10% Owner P-Purchase A Common Stock 162,539 0.98 159.3K 6,237,482 I
2025-05-13 RA CAPITAL MANAGEMENT, L.P. Director / 10% Owner P-Purchase A Common Stock 52,974 0.98 51.9K 6,074,943 I
2025-05-12 RA CAPITAL MANAGEMENT, L.P. Director / 10% Owner P-Purchase A Common Stock 320,913 0.86 276.0K 6,021,969 I
2025-05-01 Bloom Steven H. Officer A-Award A Stock Option (right to buy) 201,720 0.87 175.5K 201,720 D
2025-04-16 Bloom Steven H. 0 0.00 0
2025-03-27 MPM BioVentures 2014, L.P. 10% Owner X-InTheMoney D Warrant (Right to Buy) 18,743 0.09 1.7K 0 I
2025-03-27 GADICKE ANSBERT 10% Owner X-InTheMoney D Warrant (Right to Buy) 42,842 0.09 3.9K 0 I
2025-03-27 EVNIN LUKE Director / 10% Owner X-InTheMoney D Warrant (Right to Buy) 24,098 0.09 2.2K 0 I
2025-02-19 Singhal Anil K. Director A-Award A Stock Option (right to buy) 45,000 1.40 63.0K 45,000 D
2025-01-02 Trost Timothy W. Officer A-Award A Stock Option (right to buy) 60,358 1.56 94.2K 60,358 D
2025-01-02 Lubman Ellen Officer A-Award A Stock Option (right to buy) 131,900 1.56 205.8K 131,900 D
2025-01-02 Karunatilake Chulani Officer A-Award A Stock Option (right to buy) 150,000 1.56 234.0K 150,000 D
2025-01-02 Isaacs Randi Officer A-Award A Stock Option (right to buy) 68,151 1.56 106.3K 68,151 D
2025-01-02 HICKLIN DANIEL J Director / Officer A-Award A Stock Option (right to buy) 592,690 1.56 924.6K 592,690 D
2024-05-24 Sherman Michael A. Director A-Award A Stock Option (right to buy) 17,500 4.88 85.4K 17,500
2024-05-24 RA CAPITAL MANAGEMENT, L.P. Director / 10% Owner A-Award A Stock Option (right to buy) 17,500 4.88 85.4K 17,500
2024-05-24 Morrison Briggs Director A-Award A Stock Option (right to buy) 17,500 4.88 85.4K 17,500
2024-05-24 Lazarus Alon Director A-Award A Stock Option (right to buy) 17,500 4.88 85.4K 17,500
2024-05-24 EVNIN LUKE Director A-Award A Stock Option (right to buy) 17,500 4.88 85.4K 17,500
2024-05-24 DiRocco Derek Director A-Award A Stock Option (right to buy) 17,500 4.88 85.4K 17,500
2024-05-24 Chatterjee Meeta Director A-Award A Stock Option (right to buy) 17,500 4.88 85.4K 17,500
2024-05-24 Atkins Michael B. Director A-Award A Stock Option (right to buy) 6,723 4.88 32.8K 6,723
2024-01-04 Atkins Michael B. Director A-Award A Stock Option (right to buy) 35,000 5.25 183.8K 35,000
2024-01-02 Trost Timothy W. Officer A-Award A Stock Option (right to buy) 150,000 4.64 696.0K 150,000
2024-01-02 Seidel-Dugan Cynthia Officer A-Award A Stock Option (right to buy) 150,000 4.64 696.0K 150,000
2024-01-02 Lubman Ellen Officer A-Award A Stock Option (right to buy) 131,900 4.64 612.0K 131,900
2024-01-02 Karunatilake Chulani Officer A-Award A Stock Option (right to buy) 150,000 4.64 696.0K 150,000
2024-01-02 Isaacs Randi Officer A-Award A Stock Option (right to buy) 200,000 4.64 928.0K 200,000
2024-01-02 HICKLIN DANIEL J Director / Officer A-Award A Stock Option (right to buy) 435,000 4.64 2.02M 435,000
2023-06-21 Sherman Michael A. Director A-Award A Stock Option (right to buy) 13,200 2.81 37.1K 13,200
2023-06-21 RA CAPITAL MANAGEMENT, L.P. Director / 10% Owner A-Award D Stock Option (Right to Buy) 13,200 2.81 37.1K 13,200
2023-06-21 Morrison Briggs Director A-Award A Stock Option (right to buy) 13,200 2.81 37.1K 13,200
2023-06-21 Lazarus Alon Director A-Award A Stock Option (right to buy) 13,200 2.81 37.1K 13,200
2023-06-21 EVNIN LUKE Director A-Award A Stock Option (right to buy) 13,200 2.81 37.1K 13,200
2023-06-21 DiRocco Derek Director A-Award A Stock Option (right to buy) 13,200 2.81 37.1K 13,200
2023-06-21 Chatterjee Meeta Director A-Award A Stock Option (right to buy) 13,200 2.81 37.1K 13,200
2023-01-06 RA CAPITAL MANAGEMENT, L.P. Director P-Purchase A Common Stock 1,853,000 2.21 4.10M 5,701,056
2023-01-03 Trost Timothy W. Officer A-Award A Stock Option (right to buy) 102,800 0.00 102,800
2023-01-03 Seidel-Dugan Cynthia Officer A-Award A Stock Option (right to buy) 115,900 0.00 115,900
2023-01-03 Lubman Ellen Officer A-Award A Stock Option (right to buy) 86,200 0.00 86,200
2023-01-03 Leonard Reid Officer A-Award A Stock Option (right to buy) 93,600 0.00 93,600
2023-01-03 Karunatilake Chulani Officer A-Award A Stock Option (right to buy) 103,600 0.00 103,600
2023-01-03 Isaacs Randi Officer A-Award A Stock Option (right to buy) 103,300 0.00 103,300
2023-01-03 HICKLIN DANIEL J Officer A-Award A Stock Option (right to buy) 295,500 0.00 295,500
2022-06-01 Sherman Michael A. Director A-Award A Stock Option (right to buy) 11,600 3.43 39.8K 11,600
2022-06-01 Shah Rajeev M. Director A-Award A Stock Option (Right to Buy) 11,600 0.00 11,600
2022-06-01 RA CAPITAL MANAGEMENT, L.P. Director / 10% Owner A-Award A Stock Option (Right to Buy) 11,600 3.43 39.8K 11,600
2022-06-01 Morrison Briggs Director A-Award A Stock Option (right to buy) 11,600 3.43 39.8K 11,600
2022-06-01 Lazarus Alon Director A-Award A Stock Option (right to buy) 11,600 0.00 11,600
2022-06-01 Karunatilake Chulani Officer A-Award A Stock Option (right to buy) 136,000 0.00 136,000
2022-06-01 EVNIN LUKE Director A-Award A Stock Option (right to buy) 11,600 0.00 11,600
2022-06-01 DiRocco Derek Director A-Award A Stock Option (right to buy) 11,600 3.43 39.8K 11,600
2022-06-01 Chatterjee Meeta Director A-Award A Stock Option (right to buy) 7,733 3.43 26.5K 7,733
2022-01-12 Seidel-Dugan Cynthia Officer M-Exempt D Stock Option (right to buy) 15,532 4.77 74.1K 83,631
2022-01-06 Trost Timothy W. Officer A-Award A Stock Option (right to buy) 65,960 11.55 761.8K 65,960
2022-01-06 Seidel-Dugan Cynthia Officer A-Award A Stock Option (right to buy) 79,516 11.55 918.4K 79,516
2022-01-06 Lubman Ellen Officer A-Award A Stock Option (right to buy) 51,088 11.55 590.1K 51,088
2022-01-06 Leonard Reid Officer A-Award A Stock Option (Right to Buy) 70,967 11.55 819.7K 70,967
2022-01-06 Karunatilake Chulani Officer A-Award A Stock Option (right to buy) 34,258 11.55 395.7K 34,258
2022-01-06 Isaacs Randi Officer A-Award A Stock Option (right to buy) 79,516 11.55 918.4K 79,516
2022-01-06 HICKLIN DANIEL J Director / Officer A-Award A Stock Option (right to buy) 215,888 11.55 2.49M 215,888
2021-12-30 Leonard Reid Officer M-Exempt D Stock Option (Right to Buy) 14,102 1.56 22.0K 47,034
2021-12-15 Leonard Reid Officer S-Sale D Common Stock 135 13.97 1.9K 122,157
2021-10-28 Chatterjee Meeta Director A-Award A Stock Option (right to buy) 23,200 15.97 370.5K 23,200
2021-07-01 Karunatilake Chulani Officer A-Award A Stock Option (right to buy) 272,000 19.23 5.23M 272,000
2021-06-16 RA CAPITAL MANAGEMENT, L.P. Director / 10% Owner P-Purchase A Common Stock 9,285 13.37 124.1K 4,291,881
2021-06-15 RA CAPITAL MANAGEMENT, L.P. Director / 10% Owner P-Purchase A Common Stock 7,958 12.95 103.1K 4,282,596
2021-06-14 RA CAPITAL MANAGEMENT, L.P. Director / 10% Owner P-Purchase A Common Stock 306,055 12.75 3.90M 4,274,638
2021-06-14 Karunatilake Chulani Officer 0 0.00 0
2021-05-27 Sherman Michael A. Director A-Award A Stock Option (right to buy) 23,200 14.63 339.4K 23,200
2021-05-04 UPMC 10% Owner C-Conversion A Common Stock 273,811 0.00 1,097,756
2021-05-04 Taiho Ventures LLC 10% Owner P-Purchase A Common Stock 312,500 16.00 5.00M 2,068,909
2021-05-04 Sphera Global Healthcare Management LP 10% Owner P-Purchase A Common Stock 475,000 16.00 7.60M 787,997
2021-05-04 RA CAPITAL MANAGEMENT, L.P. Director / 10% Owner C-Conversion D Series B Preferred Stock 2,930,482 0.00 0

Executive team

Top executives
Shares Outstanding
48.60M

Executive compensation

Executive compensation (annual)
# Year Executive Salary Bonus Stock award Option award Incentive Other Total % Stock-
based
Filing
1 2024 Daniel J. Hicklin, Ph.D. President and Chief Executive Officer 608.2K 364.6K 1.56M 12.9K 2.55M 61.28%
2 2024 Randi Isaacs, M.D. Chief Medical Officer 494.1K 215.8K 717.2K 12.9K 1.44M 49.80%
3 2024 Timothy W. Trost Chief Financial Officer and Treasurer 466.0K 199.8K 537.9K 12.9K 1.22M 44.21%
4 2023 Daniel J. Hicklin, Ph.D. President and Chief Executive Officer 583.4K 332.6K 438.6K 12.3K 1.37M 32.09%
5 2023 Randi Isaacs, M.D. Chief Medical Officer 474.0K 216.1K 153.3K 12.3K 855.8K 17.92%
6 2023 Timothy W. Trost Chief Financial Officer and Treasurer 447.0K 203.8K 152.6K 12.2K 815.6K 18.71%
7 2022 Daniel J. Hicklin, Ph.D. President and Chief Executive Officer 530.4K 275.3K 1.66M 11.6K 2.47M 66.98%
8 2022 Randi Isaacs, M.D. Chief Medical Officer 442.0K 183.5K 581.7K 11.6K 1.22M 47.72%
9 2022 Cynthia Seidel-Dugan, Ph.D. Chief Scientific Officer 416.0K 172.7K 610.5K 11.6K 1.21M 50.42%
10 2022 Timothy W. Trost Chief Financial Officer and Treasurer 399.0K 165.7K 506.4K 11.6K 1.08M 46.77%
11 2021 Chulani Karunatilake, Ph.D. Chief Technology Officer 214.2K 128.0K 3.52M 1.2K 3.86M 91.11%
12 2021 Daniel J. Hicklin, Ph.D. President and Chief Executive Officer 498.5K 263.0K 1.70M 1.4K 2.46M 69.02%
13 2021 Timothy W. Trost Chief Financial Officer 337.8K 142.0K 1.61M 1.3K 2.09M 76.98%
14 2021 Randi Isaacs, M.D. Chief Medical Officer 411.8K 276.0K 621.0K 1.4K 1.31M 47.40%
15 2021 Cynthia Seidel-Dugan, Ph.D. Chief Scientific Officer 387.0K 165.0K 633.3K 1.4K 1.19M 53.37%
16 2020 Daniel J. Hicklin, Ph.D. President and Chief Executive Officer 425.0K 193.9K 2.37M 2.99M 79.30%
CEO compensation breakdown

Proxy statements

Proxy statements (DEF 14A)
Filing date Form type Filing
2025-04-28 DEFA14A
2025-04-28 DEF 14A

Recent SEC filings

Recent SEC filings
Filing date Form type Filing
2026-05-05 SC 13D/A
2026-05-04 4
2026-04-29 4
2026-03-27 8-K
2026-03-27 10-K
2026-03-13 3
2026-02-24 8-K
2026-02-13 8-K
2026-02-11 SC 13G/A
2026-02-06 8-K

Executive team

NameTitleCompensationGender
Daniel J. Hicklin Founder, Chief Executive Officer, President, Secretary & Director 645.6K
Michael Urban VP of Finance, Corporate Controller, Principal Financial Officer & Principal Accounting Officer male
Steven H. Bloom Chief Business Officer male
ESG Rating
B
BIOTECHNOLOGY
2025
E (Environmental)
58.7 / 56.3
Company / Sector avg.
S (Social)
65.1 / 62.4
Company / Sector avg.
G (Governance)
63.2 / 60.9
Company / Sector avg.
ESG Total
62.3 / 59.9
Company / Sector avg.
ESG Score History BIOTECHNOLOGY
Benchmark vs Sector
Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend history

Earnings history

Earnings reports

Stock splits